# HG changeset patch
# User pavlo-lutsik
# Date 1366199044 14400
# Node ID d1d0d07a8af4f3a43dc17539ab71748c95080020

First commit

diff -r 000000000000 -r d1d0d07a8af4 RnBeadsGalaxy.R
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/RnBeadsGalaxy.R	Wed Apr 17 07:44:04 2013 -0400
@@ -0,0 +1,154 @@
+library(RnBeads)
+library(getopt)
+
+
+
+#all.opts<-names(rnb.options())
+opt.class<-RnBeads:::OPTION.TYPES[-28]
+all.opts<-names(opt.class)
+#all.opts<-paste("--", all.opts, sep="")
+#all.opts<-gsub("\\.([a-z])", "\\U\\1", all.opts, perl=TRUE)
+all.opts<-gsub("\\.","-", all.opts)
+#opt.class<-sapply(rnb.options(), class)
+
+rnb.opt.spec<-data.frame(
+		Long=all.opts, 
+		Short=as.character(1:length(all.opts)), 
+		Mask=c(1,2)[as.integer((opt.class=="logical"))+1], 
+		Type=opt.class)
+
+### automated xml file preparation
+#xml.strings<-apply(rnb.opt.spec,1, function(row){
+#			
+#			opt.lab<-gsub("-", ".", row[1])
+#			opt.def.val<-rnb.getOption(opt.lab)
+#			opt.name<-gsub("-([0-9a-z])", "\\U\\1", row[1], perl=TRUE)
+#			tf.opt<-"\t\t\t<option value=\"True\">True</option>\n\t\t\t<option value=\"False\">False</option>"
+#			opt.lab<-paste(opt.lab, gsub("\\."," ", row[4]), sep=", ")
+#			if(row[4]=="logical"){
+#				opt.type<-'select'
+#				if(!is.null(opt.def.val) && opt.def.val)
+#					opt.def.val<-"1" else
+#					opt.def.val<-"0"
+#				string<-sprintf("\t\t<param name=\"%s\" type=\"%s\" label=\"%s\" value=\"%s\">\n%s\n\t\t</param>\n", opt.name, opt.type, opt.lab, opt.def.val, tf.opt)
+#			}else{
+#				opt.type<-'text'
+#				if(!is.null(opt.def.val) && opt.def.val!="")
+#					opt.def.val<-paste(opt.def.val, collapse=",") else
+#					opt.def.val<-""
+#				string<-sprintf("\t\t<param name=\"%s\" type=\"%s\"  label=\"%s\" value=\"%s\"/>\n", opt.name, opt.type, opt.lab, opt.def.val)
+#			}
+#			string
+#		})
+#
+#cat(xml.strings, sep="", file="C:\\Users\\User\\workspace\\RnBeads\\Supplement\\galaxy\\automated.settings.xml.txt")
+#
+#opt.def.strings<-apply(rnb.opt.spec,1, function(row){
+#			
+#			opt.name<-gsub("-([0-9a-z])", "\\U\\1", row[1], perl=TRUE)
+#			opt.long<-row[1]
+#			opt.short<-row[2]
+#			
+#			if(row[4]=="logical"){
+#				def.string<-sprintf("#if str( $options.%s ) == \"True\"\n\t--%s\n#end if\n", opt.name, opt.long)		
+#			}else{
+#				def.string<-sprintf("#if str( $options.%s ) != \"\"\n\t--%s = \"$options.%s\" \n#end if\n", opt.name, opt.long, opt.name)
+#			}
+#			def.string
+#			
+#		})
+#cat(opt.def.strings, sep="", file="C:\\Users\\User\\workspace\\RnBeads\\Supplement\\galaxy\\automated.option.assignments.txt")
+
+
+rnb.opt.spec$Type<-gsub("\\.vector", "", rnb.opt.spec$Type)
+rnb.opt.spec$Type<-gsub("numeric", "double", rnb.opt.spec$Type)
+rnb.opt.spec<-rbind(data.frame(
+				Long=c("data-type", "pheno", "idat-dir","idat-files","bed-files", "gs-report", "geo-series", "betas", "pvals","report-dir"),
+				Short=c("d","s","a","i","f","g","e","b","p","r"),
+				Mask=c(1,2,2,2,2,2,2,2,2,1),
+				Type=c("character","character","character","character","character","character","character","character","character","character")),
+				rnb.opt.spec)
+		
+opts<-getopt(as.matrix(rnb.opt.spec))
+#opts<-getopt(as.matrix(rnb.opt.spec), opt=list("--data-type=idats","--report-dir=dir", "--idats=file1\tfile2"))
+print(opts)
+
+if(opts[["data-type"]]=="idatDir"){
+   
+	data.source<-list()
+	data.type<-"idat.dir"
+	data.source[["idat.dir"]]<-opts[["idat-dir"]]
+	data.source[["sample.sheet"]]<-opts[["pheno"]]
+   
+}else if(opts[["data-type"]]=="idatFiles"){
+	
+	data.type<-"idat.dir"
+	files<-strsplit(opts[["idat-files"]], "\t")[[1]]
+	idat.dir<-mkdir(file.path(opts[["report-dir"]], "idats"))
+	file.copy(as.list(files), idat.dir)
+	data.source<-list()
+	data.source[["idat.dir"]]<-idat.dir
+	data.source[["sample.sheet"]]<-opts[["pheno"]]
+	
+	
+}else if(opts[["data-type"]]=="GS.report"){
+
+	data.type<-"GS.report"
+	data.source<-opts[["gs-report"]]
+	
+}else if(opts[["data-type"]]=="GEO"){
+	
+	data.type<-"GEO"
+	data.source<-opts[["geo-series"]]
+	
+
+}else if(opts[["data-type"]]=="data.files"){
+	
+	data.type<-"GEO"
+	data.source<-opts[["geo-series"]]
+	
+}else if(opts[["data-type"]]=="data.files"){
+	
+	data.type<-"data.files"
+	data.source<-c(opts[["pheno"]], opts[["betas"]])
+	if(!is.null(opts[["pvals"]]))
+		data.source<-c(data.source, opts[["pvals"]])
+		
+}else if(opts[["data-type"]]=="beds"){
+
+	data.type<-"idat.dir"
+	files<-strsplit(opts[["bed-files"]], "\t")[[1]]
+	bed.dir<-mkdir(file.path(opts[["report-dir"]], "beds"))
+	file.copy(as.list(files), bed.dir)
+	data.source<-list()
+	data.source[["bed.dir"]]<-bed.dir
+	data.source[["sample.sheet"]]<-opts[["pheno"]]
+
+}
+
+dump<-sapply(names(opt.class), function(on){
+	getopname<-gsub("\\.","-",on)
+	if(getoptname %in% names(opts)){
+		if(opt.class[on]=="logical"){
+			rnb.options(on=TRUE)
+		}else if(opt.class %in% c("character","character.vector")){
+			ov<-opts[[getoptname]]
+			ov<-gsub("\"", "", ov)
+			if(opt.class=="character.vector"){
+				ov<-as.character(strsplit(ov,","))
+			}
+			rnb.options(on=ov)
+		}else if(opt.class %in% c("integer","numeric","integer.vector","numeric.vector")){
+			ov<-opts[[getoptname]]
+			ov<-gsub("\"", "", ov)
+			if(opt.class %in% c("integer.vector","numeric.vector")){
+				ov<-as.character(strsplit(ov,","))
+			}
+			rnb.options(on=ov)
+		}
+	}
+})
+
+
+rnb.run.analysis(data.source=data.source, dir.report=opts[["report-dir"]], data.type=data.type)
+
diff -r 000000000000 -r d1d0d07a8af4 install.rnbeads.R
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/install.rnbeads.R	Wed Apr 17 07:44:04 2013 -0400
@@ -0,0 +1,1 @@
+source("http://rnbeads.mpi-inf.mpg.de/install.R")
\ No newline at end of file
diff -r 000000000000 -r d1d0d07a8af4 rnbeads.xml
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/rnbeads.xml	Wed Apr 17 07:44:04 2013 -0400
@@ -0,0 +1,495 @@
+<?xml version="0.9"?>
+<tool id="rnbeads" name="RnBeads" version="0.9">
+  <description>Performs RnBeads analysis for the selected set of </description>
+  <requirements>
+    <requirement type="set_environment" version="0.9">R_SCRIPTS_PATH</requirement>
+    <requirement type="package" version="3.0.0">R</requirement>
+  </requirements>
+  <command interpreter="bash">rnbeads_galaxy_wrapper.sh  
+      #if str( $inputDataSelector.dataType ) == "idat"  
+      	--data-type="idat.dir"
+      	--pheno="$inputDataSelector.sampleAnnotations"
+      	#if str( $idatSelector.idatSelector.idatSource ) == "history"
+      	--idat-files =="
+      		#for $input_files in $inputDataSelector.input_series:
+    			${input_files.input_files}\t				
+    		#end for
+    	"
+      	#else:
+      		--idat-files == "$idatRepo"
+      	#end if
+      #end if
+      #if str( $inputDataSelector.dataType ) == "gsreport"
+      	--data-type="GS.report"
+      	--gs-report="$inputDataSelector.gsReportFile"
+      #end if
+      #if str( $inputDataSelector.dataType ) == "geo"
+      	--data-type="GEO"
+      	--geo-series=$inputDataSelector.geoSeries
+      #end if
+      #if str( $inputDataSelector.dataType ) == "tables"
+        --data-type="data.files"
+        --pheno="$inputDataSelector.sampleAnnotations"
+      #end if
+      #if str( $inputDataSelector.dataType ) == "tables"
+      	--data-type="data.files"
+      	--pheno="$inputDataSelector.sampleAnnotations"
+      	--betas="$inputDataSelector.betaTable"
+      	--pvals="$inputDataSelector.pvalTable"
+      #end if
+      #if str( $inputDataSelector.dataType ) == "bed"
+        --data-type="bed.dir"
+      	--pheno="$inputDataSelector.sampleAnnotations"
+        --beds =="
+      	#for $input_files in $inputDataSelector.input_series:
+    			${input_files.input_files}\t				
+    		#end for
+      #end if
+      	--report-dir="$html_file.files_path"
+      #if str( $options.optionSet ) == "full"
+				#if str( $options.analysisName ) != ""
+					--analysis-name = "$options.analysisName" 
+				#end if
+				#if str( $options.logging ) == "True"
+					--logging
+				#end if
+				#if str( $options.email ) != ""
+					--email = "$options.email" 
+				#end if
+				#if str( $options.assembly ) != ""
+					--assembly = "$options.assembly" 
+				#end if
+				#if str( $options.analyzeSites ) == "True"
+					--analyze-sites
+				#end if
+				#if str( $options.regionTypes ) != ""
+					--region-types = "$options.regionTypes" 
+				#end if
+				#if str( $options.identifiersColumn ) != ""
+					--identifiers-column = "$options.identifiersColumn" 
+				#end if
+				#if str( $options.pointsCategory ) != ""
+					--points-category = "$options.pointsCategory" 
+				#end if
+				#if str( $options.colorsCategory ) != ""
+					--colors-category = "$options.colorsCategory" 
+				#end if
+				#if str( $options.colorsGradient ) != ""
+					--colors-gradient = "$options.colorsGradient" 
+				#end if
+				#if str( $options.minGroupSize ) != ""
+					--min-group-size = "$options.minGroupSize" 
+				#end if
+				#if str( $options.maxGroupCount ) != ""
+					--max-group-count = "$options.maxGroupCount" 
+				#end if
+				#if str( $options.gzLargeFiles ) == "True"
+					--gz-large-files
+				#end if
+				#if str( $options.strandSpecific ) == "True"
+					--strand-specific
+				#end if
+				#if str( $options.replicateIdColumn ) != ""
+					--replicate-id-column = "$options.replicateIdColumn" 
+				#end if
+				#if str( $options.loadingNormalization ) == "True"
+					--loading-normalization
+				#end if
+				#if str( $options.loadingDefaultDataType ) != ""
+					--loading-default-data-type = "$options.loadingDefaultDataType" 
+				#end if
+				#if str( $options.loadingTableSeparator ) != ""
+					--loading-table-separator = "$options.loadingTableSeparator" 
+				#end if
+				#if str( $options.loadingBedStyle ) != ""
+					--loading-bed-style = "$options.loadingBedStyle" 
+				#end if
+				#if str( $options.loadingBedColumns ) != ""
+					--loading-bed-columns = "$options.loadingBedColumns" 
+				#end if
+				#if str( $options.loadingBedFrameShift ) != ""
+					--loading-bed-frame-shift = "$options.loadingBedFrameShift" 
+				#end if
+				#if str( $options.normalizationMethod ) != ""
+					--normalization-method = "$options.normalizationMethod" 
+				#end if
+				#if str( $options.qc ) == "True"
+					--qc
+				#end if
+				#if str( $options.qcBoxplots ) == "True"
+					--qc-boxplots
+				#end if
+				#if str( $options.qcBarplots ) == "True"
+					--qc-barplots
+				#end if
+				#if str( $options.qcNegativeBoxplot ) == "True"
+					--qc-negative-boxplot
+				#end if
+				#if str( $options.qcSnpHeatmap ) == "True"
+					--qc-snp-heatmap
+				#end if
+				#if str( $options.qcSnpBoxplot ) == "True"
+					--qc-snp-boxplot
+				#end if
+				#if str( $options.qcSnpBarplot ) == "True"
+					--qc-snp-barplot
+				#end if
+				#if str( $options.qcSampleBatchSize ) != ""
+					--qc-sample-batch-size = "$options.qcSampleBatchSize" 
+				#end if
+				#if str( $options.filteringContextRemoval ) != ""
+					--filtering-context-removal = "$options.filteringContextRemoval" 
+				#end if
+				#if str( $options.filteringSnp ) == "True"
+					--filtering-snp
+				#end if
+				#if str( $options.filteringSnpFrequency ) != ""
+					--filtering-snp-frequency = "$options.filteringSnpFrequency" 
+				#end if
+				#if str( $options.filteringSnpAccepted ) != ""
+					--filtering-snp-accepted = "$options.filteringSnpAccepted" 
+				#end if
+				#if str( $options.filteringSexChromosomesRemoval ) == "True"
+					--filtering-sex-chromosomes-removal
+				#end if
+				#if str( $options.filteringMissingValueQuantile ) != ""
+					--filtering-missing-value-quantile = "$options.filteringMissingValueQuantile" 
+				#end if
+				#if str( $options.filteringCoverageThreshold ) != ""
+					--filtering-coverage-threshold = "$options.filteringCoverageThreshold" 
+				#end if
+				#if str( $options.filteringLowCoverageMasking ) == "True"
+					--filtering-low-coverage-masking
+				#end if
+				#if str( $options.filteringHighCoverageOutliers ) == "True"
+					--filtering-high-coverage-outliers
+				#end if
+				#if str( $options.filteringGreedycut ) == "True"
+					--filtering-greedycut
+				#end if
+				#if str( $options.filteringGreedycutPvalueThreshold ) != ""
+					--filtering-greedycut-pvalue-threshold = "$options.filteringGreedycutPvalueThreshold" 
+				#end if
+				#if str( $options.filteringGreedycutRcTies ) != ""
+					--filtering-greedycut-rc-ties = "$options.filteringGreedycutRcTies" 
+				#end if
+				#if str( $options.filteringDeviationThreshold ) != ""
+					--filtering-deviation-threshold = "$options.filteringDeviationThreshold" 
+				#end if
+				#if str( $options.batch ) == "True"
+					--batch
+				#end if
+				#if str( $options.batchDreductionColumns ) != ""
+					--batch-dreduction-columns = "$options.batchDreductionColumns" 
+				#end if
+				#if str( $options.batchPrincipalComponents ) != ""
+					--batch-principal-components = "$options.batchPrincipalComponents" 
+				#end if
+				#if str( $options.batchCorrelationColumns ) != ""
+					--batch-correlation-columns = "$options.batchCorrelationColumns" 
+				#end if
+				#if str( $options.batchCorrelationPvalueThreshold ) != ""
+					--batch-correlation-pvalue-threshold = "$options.batchCorrelationPvalueThreshold" 
+				#end if
+				#if str( $options.batchCorrelationPermutations ) != ""
+					--batch-correlation-permutations = "$options.batchCorrelationPermutations" 
+				#end if
+				#if str( $options.batchCorrelationQc ) == "True"
+					--batch-correlation-qc
+				#end if
+				#if str( $options.profiles ) == "True"
+					--profiles
+				#end if
+				#if str( $options.profilesBetaDistribution ) == "True"
+					--profiles-beta-distribution
+				#end if
+				#if str( $options.profilesIntersample ) == "True"
+					--profiles-intersample
+				#end if
+				#if str( $options.profilesDeviationPlots ) == "True"
+					--profiles-deviation-plots
+				#end if
+				#if str( $options.profilesColumns ) != ""
+					--profiles-columns = "$options.profilesColumns" 
+				#end if
+				#if str( $options.profilesClustering ) == "True"
+					--profiles-clustering
+				#end if
+				#if str( $options.profilesClusteringTopProbes ) != ""
+					--profiles-clustering-top-probes = "$options.profilesClusteringTopProbes" 
+				#end if
+				#if str( $options.regionProfilesTypes ) != ""
+					--region-profiles-types = "$options.regionProfilesTypes" 
+				#end if
+				#if str( $options.differential ) == "True"
+					--differential
+				#end if
+				#if str( $options.differentialPermutations ) != ""
+					--differential-permutations = "$options.differentialPermutations" 
+				#end if
+				#if str( $options.differentialComparisonColumns ) != ""
+					--differential-comparison-columns = "$options.differentialComparisonColumns" 
+				#end if
+				#if str( $options.differentialEnrichment ) == "True"
+					--differential-enrichment
+				#end if
+				#if str( $options.exportToUcsc ) != ""
+					--export-to-ucsc = "$options.exportToUcsc" 
+				#end if
+				#if str( $options.exportToBed ) == "True"
+					--export-to-bed
+				#end if
+				#if str( $options.exportToCsv ) == "True"
+					--export-to-csv
+				#end if
+				#if str( $options.exportTypes ) != ""
+					--export-types = "$options.exportTypes" 
+				#end if
+				#if str( $options.colors3Gradient ) != ""
+					--colors-3-gradient = "$options.colors3Gradient" 
+				#end if
+				#if str( $options.loggingMemory ) == "True"
+					--logging-memory
+				#end if
+				#if str( $options.usePstoimg ) == "True"
+					--use-pstoimg
+				#end if
+      #end if
+  </command>
+  <inputs>
+    <conditional name="inputDataSelector">
+    	<param name="dataType" type="select" label="Data Type">
+    		<option value="tables">Tabular data</option>
+    		<option value="idats">IDAT files</option>
+    		<option value="gsreport">GenomeStudio report</option>
+    		<option value="geo">Gene Expression Omnibus series</option>		
+    		<option value="bed">BED files</option>
+    	</param>
+    	<when value="tables">
+    		<param name="sampleAnnotations" type="data" format="tabular" label="Sample Annotation File"/>
+    		<param name="betaTable" type="data" format="tabular" label="Table with beta-values"/> 	
+    		<param name="pvalTable" type="data" format="tabular" label="Table with detection p\-values"/>
+    	</when>
+    	<when value="idats">
+    		<param name="sampleAnnotations" type="data" format="tabular" label="Sample Annotation File"/>
+    		<conditional name="idatSelector">
+    			<param name="idatSource" type="select" label="IDAT source">
+    				<option value="history">Select from history</option>
+    				<option value="repo">Repository on the server</option>
+    			</param>
+    			<when value="repo">
+    				<param name="idatRepo" type="select" label="Select an IDAT repository">
+    					<options from_data_table="rnbeads_repos">
+            				<filter type="sort_by" column="2" />
+            				<validator type="no_options" message="No repositories are available" />
+          				</options>
+          			</param>
+    			</when>
+    			<when value="history">
+    				<repeat min="1" name="idatSeries" title="Input IDAT file">
+    					<param name="idatFiles" type="data" format="idat" label="IDAT file"/>
+    				</repeat>
+    			</when>
+    		</conditional>
+    	</when>
+    	<when value="gsreport">
+    		<param name="gsReportFile" type="data" format="tabular" label="GenomeStudio report" />
+    	</when>
+    	<when value="geo">
+    		<param name="geoSeries" type="text" label="GEO series" />
+    	</when>
+    	<when value="bed">
+    		<param name="sampleAnnotations" type="data" format="tabular" label="Sample Annotation File" />
+   				<repeat min="1" name="bedSeries" title="Input BED file">
+    					<param name="idatFiles" type="data" format="idat"/>
+    		    </repeat>    	
+        </when>
+    </conditional>
+    <conditional name="options">
+    	<param name="optionSet" type="select" label="Options Set">
+    		<option value="default">Default options</option>
+    		<option value="full">Full option set</option>
+    	</param>
+    	<when value="default" />
+    	<when value="full">
+    			<label>See package documentation for detailed description of each option</label>
+				<param name="analysisName" type="text"  label="analysis.name, character" value=""/>
+				<param name="logging" type="select" label="logging, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="email" type="text"  label="email, character" value=""/>
+				<param name="assembly" type="text"  label="assembly, character" value="hg19"/>
+				<param name="analyzeSites" type="select" label="analyze.sites, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="regionTypes" type="text"  label="region.types, character vector" value="tiling,genes,promoters,cpgislands"/>
+				<param name="identifiersColumn" type="text"  label="identifiers.column, character" value=""/>
+				<param name="pointsCategory" type="text"  label="points.category, integer vector" value="16,17,3,15,4,7,8"/>
+				<param name="colorsCategory" type="text"  label="colors.category, character vector" value="#1B9E77,#D95F02,#7570B3,#E7298A,#66A61E,#E6AB02,#A6761D,#666666"/>
+				<param name="colorsGradient" type="text"  label="colors.gradient, character vector" value="#132B43,#56B1F7"/>
+				<param name="minGroupSize" type="text"  label="min.group.size, integer" value="2"/>
+				<param name="maxGroupCount" type="text"  label="max.group.count, integer" value="8"/>
+				<param name="gzLargeFiles" type="select" label="gz.large.files, logical" value="0">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="strandSpecific" type="select" label="strand.specific, logical" value="0">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="replicateIdColumn" type="text"  label="replicate.id.column, character" value=""/>
+				<param name="loadingNormalization" type="select" label="loading.normalization, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="loadingDefaultDataType" type="text"  label="loading.default.data.type, character" value="idat.dir"/>
+				<param name="loadingTableSeparator" type="text"  label="loading.table.separator, character" value=","/>
+				<param name="loadingBedStyle" type="text"  label="loading.bed.style, character" value="BisSNP"/>
+				<param name="loadingBedColumns" type="text"  label="loading.bed.columns, integer vector" value="1,2,3,6,4,5"/>
+				<param name="loadingBedFrameShift" type="text"  label="loading.bed.frame.shift, integer" value="1"/>
+				<param name="normalizationMethod" type="text"  label="normalization.method, character" value="illumina"/>
+				<param name="qc" type="select" label="qc, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="qcBoxplots" type="select" label="qc.boxplots, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="qcBarplots" type="select" label="qc.barplots, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="qcNegativeBoxplot" type="select" label="qc.negative.boxplot, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="qcSnpHeatmap" type="select" label="qc.snp.heatmap, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="qcSnpBoxplot" type="select" label="qc.snp.boxplot, logical" value="0">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="qcSnpBarplot" type="select" label="qc.snp.barplot, logical" value="0">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="qcSampleBatchSize" type="text"  label="qc.sample.batch.size, integer" value="50"/>
+				<param name="filteringContextRemoval" type="text"  label="filtering.context.removal, character vector" value="CC,CAG,CAH,CTG,CTH,Other"/>
+				<param name="filteringSnp" type="select" label="filtering.snp, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="filteringSnpFrequency" type="text"  label="filtering.snp.frequency, double" value="0.01"/>
+				<param name="filteringSnpAccepted" type="text"  label="filtering.snp.accepted, integer" value="2"/>
+				<param name="filteringSexChromosomesRemoval" type="select" label="filtering.sex.chromosomes.removal, logical" value="0">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="filteringMissingValueQuantile" type="text"  label="filtering.missing.value.quantile, double" value="1"/>
+				<param name="filteringCoverageThreshold" type="text"  label="filtering.coverage.threshold, integer" value="5"/>
+				<param name="filteringLowCoverageMasking" type="select" label="filtering.low.coverage.masking, logical" value="0">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="filteringHighCoverageOutliers" type="select" label="filtering.high.coverage.outliers, logical" value="0">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="filteringGreedycut" type="select" label="filtering.greedycut, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="filteringGreedycutPvalueThreshold" type="text"  label="filtering.greedycut.pvalue.threshold, double" value="0.05"/>
+				<param name="filteringGreedycutRcTies" type="text"  label="filtering.greedycut.rc.ties, character" value="row"/>
+				<param name="filteringDeviationThreshold" type="text"  label="filtering.deviation.threshold, double" value="0"/>
+				<param name="batch" type="select" label="batch, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="batchDreductionColumns" type="text"  label="batch.dreduction.columns, integer vector" value=""/>
+				<param name="batchPrincipalComponents" type="text"  label="batch.principal.components, integer" value="8"/>
+				<param name="batchCorrelationColumns" type="text"  label="batch.correlation.columns, integer vector" value=""/>
+				<param name="batchCorrelationPvalueThreshold" type="text"  label="batch.correlation.pvalue.threshold, double" value="0.01"/>
+				<param name="batchCorrelationPermutations" type="text"  label="batch.correlation.permutations, integer" value="10000"/>
+				<param name="batchCorrelationQc" type="select" label="batch.correlation.qc, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="profiles" type="select" label="profiles, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="profilesBetaDistribution" type="select" label="profiles.beta.distribution, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="profilesIntersample" type="select" label="profiles.intersample, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="profilesDeviationPlots" type="select" label="profiles.deviation.plots, logical" value="0">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="profilesColumns" type="text"  label="profiles.columns, integer vector" value=""/>
+				<param name="profilesClustering" type="select" label="profiles.clustering, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="profilesClusteringTopProbes" type="text"  label="profiles.clustering.top.probes, integer vector" value="1000"/>
+				<param name="regionProfilesTypes" type="text"  label="region.profiles.types, character vector" value="genes,promoters,cpgislands"/>
+				<param name="differential" type="select" label="differential, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="differentialPermutations" type="text"  label="differential.permutations, integer" value="0"/>
+				<param name="differentialComparisonColumns" type="text"  label="differential.comparison.columns, integer vector" value=""/>
+				<param name="differentialEnrichment" type="select" label="differential.enrichment, logical" value="0">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="exportToUcsc" type="text"  label="export.to.ucsc, character vector" value="bigBed,bigWig"/>
+				<param name="exportToBed" type="select" label="export.to.bed, logical" value="1">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="exportToCsv" type="select" label="export.to.csv, logical" value="0">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="exportTypes" type="text"  label="export.types, character vector" value=""/>
+				<param name="colors3Gradient" type="text"  label="colors.3.gradient, character vector" value="#832424,#FFFFFF,#3A3A98"/>
+				<param name="loggingMemory" type="select" label="logging.memory, logical" value="0">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+				<param name="usePstoimg" type="select" label="use.pstoimg, logical" value="0">
+					<option value="True">True</option>
+					<option value="False">False</option>
+				</param>
+    	</when>
+    </conditional>
+  </inputs>
+  
+  <outputs>
+	<data format="html" name="html_file" label="index.html" />
+  </outputs>
+
+  <!--
+  <tests>
+    <test>
+      <param name="input" value="fa_gc_content_input.fa"/>
+      <output name="out_file1" file="fa_gc_content_output.txt"/>
+    </test>
+  </tests>  -->
+
+  <help>
+	RnBeads is an R-package for comprehensive analysis of Illumina Infinium HumanMethylation450 BeadChip data. It extends previous approaches for this type of data analysis by high throughput capabilities, as well as presenting results in a comprehensive, highly interpretable fashion.
+  </help>
+
+</tool>
\ No newline at end of file
diff -r 000000000000 -r d1d0d07a8af4 rnbeads_galaxy_wrapper.sh
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/rnbeads_galaxy_wrapper.sh	Wed Apr 17 07:44:04 2013 -0400
@@ -0,0 +1,4 @@
+#!/bin/bash
+
+#Rscript  --slave $(dirname $(readlink -f $0))/RnBeadsGalaxy.R $*
+Rscript  --slave \$R_SCRIPTS_PATH/RnBeadsGalaxy.R $*
\ No newline at end of file
diff -r 000000000000 -r d1d0d07a8af4 rnbeads_repos.txt.sample
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/rnbeads_repos.txt.sample	Wed Apr 17 07:44:04 2013 -0400
@@ -0,0 +1,1 @@
+repo1	Repository1	/data/iscan/idats
\ No newline at end of file
diff -r 000000000000 -r d1d0d07a8af4 tool_data_table_conf.xml.sample
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool_data_table_conf.xml.sample	Wed Apr 17 07:44:04 2013 -0400
@@ -0,0 +1,6 @@
+<tables>
+	<table name="rnbeads_repos" comment_char="#">
+       		<columns>id, name, value</columns>
+        	<file path="tool-data/rnbeads_repos.txt" />
+	</table>
+</tables>
\ No newline at end of file
diff -r 000000000000 -r d1d0d07a8af4 tool_dependencies.xml
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool_dependencies.xml	Wed Apr 17 07:44:04 2013 -0400
@@ -0,0 +1,22 @@
+<?xml version="1.0"?>
+<tool_dependency>
+    <set_environment version="0.9">
+        <environment_variable name="R_SCRIPTS_PATH" action="set_to">$REPOSITORY_INSTALL_DIR</environment_variable>
+    </set_environment>
+    <package name="R" version="3.0.0">
+        <install version="0.9">
+            <actions>
+                <action type="download_by_url">http://CRAN.R-project.org/src/base/R-3/R-3.0.0.tar.gz</action>
+                <action type="shell_command">./configure --prefix=$INSTALL_DIR --with-x=no</action>
+                <action type="shell_command">make</action>
+                <action type="set_environment">
+                    <environment_variable name="PATH" action="prepend_to">$INSTALL_DIR/bin</environment_variable>
+                </action>
+                <action type="shell_command">R --no-save &lt;&lt;&lt; "source('http://rnbeads.mpi-inf.mpg.de')"</action>
+            </actions>
+        </install>
+        <readme>
+				You need a FORTRAN compiler or perhaps f2c in addition to a C compiler to build R.
+        </readme>
+    </package>
+</tool_dependency>
\ No newline at end of file