annotate tools/protein_analysis/clinod.xml @ 0:b8be455c27d1

Uploaded wrapper v0.0.1 (for clinod v1.3)
author peterjc
date Tue, 02 Aug 2011 06:51:52 -0400
parents
children 221d7dca03a5
Ignore whitespace changes - Everywhere: Within whitespace: At end of lines:
rev   line source
0
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
1 <tool id="clinod" name="Nucleolar localization sequence Detector (NoD)" version="0.0.1">
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
2 <description>Find nucleolar localization signals (NoLSs) in protein sequences</description>
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
3 <command>
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
4 java -jar /opt/clinod/clinod-1.3.jar -in="$fasta_file" -out="$tabular_file" -t=8 -f=MEDIUM_TAB -nonols -clean_sequence
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
5 ##I want the number of threads to be a Galaxy config option...
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
6 ##TODO - Make the -clean_sequece argument a parameter?
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
7 </command>
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
8 <inputs>
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
9 <param name="fasta_file" type="data" format="fasta" label="FASTA file of protein sequences"/>
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
10 </inputs>
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
11 <outputs>
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
12 <data name="tabular_file" format="tabular" label="NoD results" />
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
13 </outputs>
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
14 <requirements>
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
15 <requirement type="binary">java</requirement>
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
16 </requirements>
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
17 <help>
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
18
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
19 **What it does**
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
20
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
21 This calls the command line version of the NoD tool from the Barton Group for
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
22 prediction of nucleolar localization sequences (NoLSs). The NoD tool uses an
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
23 artificial neural network trained on a set of human NoLSs.
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
24
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
25 The nucleolus is a sub-compartmentof the nucleus, thus an NoLS can be regarded
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
26 as a special nuclear localization sequence (NLS).
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
27
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
28 The input is a FASTA file of protein sequences, and the output is tabular with
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
29 four columns (multiple rows per protein):
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
30
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
31 * Sequence identifier
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
32 * Start of NoLS
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
33 * End of NoLS
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
34 * NoLS sequence
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
35
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
36 If a sequence has no predicted NoLS, then there is no line in the output file
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
37 for it.
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
38
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
39 **References**
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
40
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
41 M. S. Scott, F. M. Boisvert, M. D. McDowall, A. I. Lamond and G. J. Barton.
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
42 Characterization and prediction of protein nucleolar localization sequences.
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
43 Nucleic Acids Research 38(21), 7388-7399, 2010.
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
44 http://dx.doi.org/10.1093/nar/gkq653
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
45
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
46 M. S. Scott, P. V. Troshin and G. J. Barton.
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
47 NoD: a Nucleolar localization sequence detector for eukaryotic and viral proteins.
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
48 BMC Bioinformatics, in press, 2011.
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
49
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
50 http://www.compbio.dundee.ac.uk/www-nod/
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
51
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
52 </help>
b8be455c27d1 Uploaded wrapper v0.0.1 (for clinod v1.3)
peterjc
parents:
diff changeset
53 </tool>