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1 Wrapper for clusterProfiler Enrichment Analysis Tool
2 ====================================================
3
4 **Authors**
5
6 clusterProfiler R package reference :
7 G Yu, LG Wang, Y Han, QY He. clusterProfiler: an R package for comparing biological themes among gene clusters.
8 OMICS: A Journal of Integrative Biology 2012, 16(5):284-287.
9 doi:[10.1089/omi.2011.0118](http://dx.doi.org/10.1089/omi.2011.0118)
10
11
12 **Galaxy integration**
13
14 T.P. Lien Nguyen, Florence Combes, Yves Vandenbrouck CEA, INSERM, CNRS, Grenoble-Alpes University, BIG Institute, FR
15
16 Sandra Dérozier, Olivier Rué, Christophe Caron, Valentin Loux INRA, Paris-Saclay University, MAIAGE Unit, Migale Bioinformatics platform
17
18 This work has been partially funded through the French National Agency for Research (ANR) IFB project.
19
20 Contact support@proteore.org for any questions or concerns about the Galaxy implementation of this tool.
21
22
23 ===================
24
25 **Galaxy component based on R package clusterProfiler (see ref below)**
26
27 This component allows to perform GO enrichment-analyses.
28 Given a list of IDs, the tool either
29 (i) performs gene classification based on GO distribution at a specific level, or
30 (ii) calculates GO categories enrichment (over- or under-representation) for the IDs of the input list,
31 compared to a background (whole organism or user-defined list).
32
33 **Input required**
34
35 This component works with Gene ids (e.g : 4151, 7412) or Uniprot accession number (e.g. P31946).
36 You can copy/paste these identifiers or supply a tabular file (.csv, .tsv, .txt, .tab) where there are contained.
37
38
39 **Output**
40
41 Text (tables) and graphics representing the repartition and/or enrichment of GO categories.
42
43 **User manual / Documentation** of the clusterProfiler R package (functions and parameters):
44 https://bioconductor.org/packages/3.7/bioc/vignettes/clusterProfiler/inst/doc/clusterProfiler.html
45 (Very well explained)