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comparison test-data/SAMN11840203-abricate_report_full.tsv @ 4:22247b1a59d5 draft default tip

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"planemo upload for repository https://github.com/public-health-bioinformatics/galaxy_tools/blob/master/tools/screen_abricate_report commit ae10b1f55b2356bea735a994619288f7575430cb"
author public-health-bioinformatics
date Fri, 03 Jan 2020 14:30:22 -0500
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3:2262e531c50b 4:22247b1a59d5
1 #FILE SEQUENCE START END STRAND GENE COVERAGE COVERAGE_MAP GAPS %COVERAGE %IDENTITY DATABASE ACCESSION PRODUCT RESISTANCE
2 SAMN11840203 contig00001 316814 317172 + Klebsiella_pneumoniae_KpnE 5-363/363 ========/====== 2/2 98.62 76.67 card AP006725.1:2483890-2484253 KpnE subunit of KpnEF resembles EbrAB from E. coli. Mutation in KpnEF resulted in increased susceptibility to cefepime ceftriaxon colistin erythromycin rifampin tetracycline and streptomycin as well as enhanced sensitivity toward sodium dodecyl sulfate deoxycholate dyes benzalkonium chloride chlorhexidine and triclosan diaminopyrimidine/bicyclomycin/antibacterial_free_fatty_acids/benzalkonium_chloride/isoniazid/lincosamide/nucleoside/nitroimidazole/rifamycin/penam/macrolide/aminoglycoside/peptide/rhodamine/phenicol/glycylcycline/fosfomycin/oxazolidinone/acridine_dye/tetracycline/fluoroquinolone/cephalosporin
3 SAMN11840203 contig00001 317164 317488 + Klebsiella_pneumoniae_KpnF 6-330/330 =============== 0/0 98.48 75.69 card AP006725.1:2484239-2484569 KpnF subunit of KpnEF resembles EbrAB from E. coli. Mutation in KpnEF resulted in increased susceptibility to cefepime ceftriaxon colistin erythromycin rifampin tetracycline and streptomycin as well as enhanced sensitivity toward sodium dodecyl sulfate deoxycholate dyes benzalkonium chloride chlorhexidine and triclosan. fosfomycin/glycylcycline/phenicol/cephalosporin/fluoroquinolone/acridine_dye/oxazolidinone/tetracycline/aminoglycoside/rhodamine/peptide/rifamycin/nitroimidazole/nucleoside/macrolide/penam/bicyclomycin/antibacterial_free_fatty_acids/diaminopyrimidine/isoniazid/lincosamide/benzalkonium_chloride
4 SAMN11840203 contig00001 355656 356039 - marA 1-384/384 =============== 0/0 100.00 99.48 card AP009048.1:1621288-1621672 In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. antibacterial_free_fatty_acids/penem/diaminopyrimidine/macrolide/penam/rifamycin/cephamycin/aminocoumarin/carbapenem/aminoglycoside/cephalosporin/fluoroquinolone/tetracycline/triclosan/acridine_dye/monobactam/glycylcycline/phenicol
5 SAMN11840203 contig00002 118693 120180 + tolC 1-1488/1488 =============== 0/0 100.00 98.52 card FJ768952:1-1489 TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. rifamycin/triclosan/tetracycline/glycylcycline/cephamycin/carbapenem/aminoglycoside/macrolide/penam/pleuromutilin/nitroimidazole/nucleoside/isoniazid/lincosamide/benzalkonium_chloride/antibacterial_free_fatty_acids/bicyclomycin/penem/diaminopyrimidine/cephalosporin/fluoroquinolone/oxazolidinone/acridine_dye/fosfomycin/monobactam/phenicol/rhodamine/peptide/aminocoumarin
6 SAMN11840203 contig00002 140892 141711 - bacA 1-820/822 =============== 0/0 99.76 96.22 card U00096.3:3203310-3204132 The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. peptide
7 SAMN11840203 contig00002 340230 340892 - acrS 1-663/663 =============== 0/0 100.00 98.94 card U00096:3412803-3413466 AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. glycylcycline/monobactam/phenicol/acridine_dye/triclosan/tetracycline/cephalosporin/fluoroquinolone/carbapenem/aminoglycoside/aminocoumarin/cephamycin/rifamycin/macrolide/penam/diaminopyrimidine/antibacterial_free_fatty_acids
8 SAMN11840203 contig00002 341291 342448 + acrE 1-1158/1158 =============== 0/0 100.00 98.36 card U00096:3413864-3415022 AcrE is a membrane fusion protein similar to AcrA. aminocoumarin/cephamycin/carbapenem/diaminopyrimidine/aminoglycoside/antibacterial_free_fatty_acids/triclosan/tetracycline/acridine_dye/cephalosporin/macrolide/penam/fluoroquinolone/monobactam/glycylcycline/phenicol
9 SAMN11840203 contig00002 342460 345564 + acrF 1-3105/3105 =============== 0/0 100.00 97.78 card U00096:3415033-3418138 AcrF is a inner membrane transporter similar to AcrB. aminoglycoside/carbapenem/diaminopyrimidine/antibacterial_free_fatty_acids/aminocoumarin/cephamycin/phenicol/monobactam/glycylcycline/tetracycline/triclosan/acridine_dye/fluoroquinolone/penam/cephalosporin/macrolide
10 SAMN11840203 contig00003 31686 35279 - evgS 1-3594/3594 =============== 0/0 100.00 96.83 card U00096:2484374-2487968 EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. triclosan/tetracycline/acridine_dye/oxazolidinone/fluoroquinolone/cephalosporin/phenicol/monobactam/glycylcycline/fosfomycin/aminocoumarin/peptide/rhodamine/aminoglycoside/carbapenem/penam/macrolide/nucleoside/nitroimidazole/rifamycin/benzalkonium_chloride/isoniazid/lincosamide/diaminopyrimidine/antibacterial_free_fatty_acids/bicyclomycin
11 SAMN11840203 contig00003 35284 35898 - evgA 1-615/615 =============== 0/0 100.00 99.02 card BA000007.3:3212026-3212641 EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. diaminopyrimidine/antibacterial_free_fatty_acids/bicyclomycin/benzalkonium_chloride/isoniazid/lincosamide/nucleoside/nitroimidazole/rifamycin/penam/macrolide/aminoglycoside/carbapenem/aminocoumarin/peptide/rhodamine/phenicol/monobactam/glycylcycline/fosfomycin/triclosan/tetracycline/oxazolidinone/acridine_dye/fluoroquinolone/cephalosporin
12 SAMN11840203 contig00003 36422 37477 + emrK 1-1056/1056 =============== 0/0 100.00 97.82 card D78168:537-1593 emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. macrolide/penam/rifamycin/nitroimidazole/nucleoside/isoniazid/lincosamide/benzalkonium_chloride/bicyclomycin/antibacterial_free_fatty_acids/diaminopyrimidine/cephalosporin/fluoroquinolone/acridine_dye/oxazolidinone/tetracycline/fosfomycin/glycylcycline/phenicol/rhodamine/peptide
13 SAMN11840203 contig00003 37477 39015 + emrY 1-1539/1539 =============== 0/0 100.00 97.47 card D78168:1592-3131 emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. oxazolidinone/acridine_dye/tetracycline/cephalosporin/fluoroquinolone/glycylcycline/phenicol/fosfomycin/peptide/rhodamine/macrolide/penam/nucleoside/rifamycin/nitroimidazole/lincosamide/isoniazid/benzalkonium_chloride/diaminopyrimidine/bicyclomycin/antibacterial_free_fatty_acids
14 SAMN11840203 contig00003 140616 141584 - pmrF 1-969/969 =============== 0/0 100.00 98.14 card U00096:2367071-2368040 PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. peptide
15 SAMN11840203 contig00003 203080 204723 + yojI 1-1644/1644 =============== 0/0 100.00 97.51 card U00096.3:2306972-2308616 YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. peptide/nitroimidazole/rifamycin/pleuromutilin/penam/fluoroquinolone/cephalosporin/macrolide/tetracycline/acridine_dye
16 SAMN11840203 contig00005 39446 41194 + msbA 1-1749/1749 =============== 0/0 100.00 98.97 card U00096.3:966621-968370 MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. peptide/rifamycin/pleuromutilin/nitroimidazole/tetracycline/acridine_dye/cephalosporin/macrolide/penam/fluoroquinolone
17 SAMN11840203 contig00005 174588 175814 - mdtG 1-1227/1227 =============== 0/0 100.00 98.45 card CP000800.1:1191728-1192955 The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. macrolide/penam/rifamycin/nitroimidazole/nucleoside/isoniazid/lincosamide/benzalkonium_chloride/bicyclomycin/antibacterial_free_fatty_acids/diaminopyrimidine/cephalosporin/fluoroquinolone/acridine_dye/oxazolidinone/tetracycline/fosfomycin/glycylcycline/phenicol/rhodamine/peptide
18 SAMN11840203 contig00005 184445 185653 - mdtH 1-1209/1209 =============== 0/0 100.00 97.85 card U00096:1124118-1125327 Multidrug resistance protein MdtH nitroimidazole/rifamycin/nucleoside/penam/macrolide/antibacterial_free_fatty_acids/bicyclomycin/diaminopyrimidine/benzalkonium_chloride/isoniazid/lincosamide/fosfomycin/phenicol/glycylcycline/fluoroquinolone/cephalosporin/tetracycline/acridine_dye/oxazolidinone/rhodamine/peptide
19 SAMN11840203 contig00006 89461 90927 - mdtP 1-1467/1467 =============== 0/0 100.00 97.48 card AP009048.1:4303043-4304510 Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride benzalkonium_chloride/isoniazid/lincosamide/antibacterial_free_fatty_acids/bicyclomycin/diaminopyrimidine/penam/macrolide/nitroimidazole/rifamycin/nucleoside/rhodamine/peptide/fluoroquinolone/cephalosporin/tetracycline/acridine_dye/oxazolidinone/fosfomycin/phenicol/glycylcycline
20 SAMN11840203 contig00006 90924 92975 - mdtO 1-2052/2052 =============== 0/0 100.00 96.34 card AP009048.1:4304506-4306558 Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride nucleoside/rifamycin/nitroimidazole/macrolide/penam/diaminopyrimidine/bicyclomycin/antibacterial_free_fatty_acids/isoniazid/lincosamide/benzalkonium_chloride/glycylcycline/phenicol/fosfomycin/oxazolidinone/acridine_dye/tetracycline/cephalosporin/fluoroquinolone/peptide/rhodamine
21 SAMN11840203 contig00006 92975 94006 - mdtN 1-1032/1032 =============== 0/0 100.00 96.42 card AP009048.1:4306557-4307589 Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. tetracycline/oxazolidinone/acridine_dye/cephalosporin/fluoroquinolone/glycylcycline/phenicol/fosfomycin/peptide/rhodamine/macrolide/penam/nucleoside/rifamycin/nitroimidazole/isoniazid/lincosamide/benzalkonium_chloride/diaminopyrimidine/antibacterial_free_fatty_acids/bicyclomycin
22 SAMN11840203 contig00006 116674 118317 - eptA 1-1644/1644 =============== 0/0 100.00 98.17 card AP009048:4338625-4340269 PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. peptide
23 SAMN11840203 contig00006 160236 161369 - Escherichia_coli_ampC 1-1134/1134 =============== 0/0 100.00 97.62 card NC_000913.3:4377811-4378945 A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. cephalosporin/penam
24 SAMN11840203 contig00007 24627 25784 + Escherichia_coli_ampH 1-1158/1158 =============== 0/0 100.00 96.89 card AP012030.1:395554-396712 AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. cephalosporin/penam
25 SAMN11840203 contig00008 19475 22588 + acrD 1-3114/3114 =============== 0/0 100.00 98.75 card AP009048.1:2586251-2589365 AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. aminocoumarin/aminoglycoside/carbapenem/diaminopyrimidine/antibacterial_free_fatty_acids/tetracycline/triclosan/acridine_dye/fluoroquinolone/penam/macrolide/phenicol/monobactam/glycylcycline
26 SAMN11840203 contig00008 43295 43769 + mphB 3-477/477 =============== 0/0 99.58 96.63 card AE005174.2:3397371-3397848 The mphB gene encodes for MPH(2')-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2'-OH hydroxyl of desosamine sugar of macrolides. macrolide
27 SAMN11840203 contig00009 22558 22971 - H-NS 1-414/414 =============== 0/0 100.00 99.52 card BA000007.3:1737691-1738105 H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. bicyclomycin/antibacterial_free_fatty_acids/diaminopyrimidine/benzalkonium_chloride/isoniazid/lincosamide/nitroimidazole/rifamycin/nucleoside/penam/macrolide/aminoglycoside/carbapenem/rhodamine/cephamycin/aminocoumarin/peptide/fosfomycin/phenicol/glycylcycline/monobactam/fluoroquinolone/cephalosporin/acridine_dye/oxazolidinone/triclosan/tetracycline
28 SAMN11840203 contig00010 109634 110866 + Escherichia_coli_mdfA 1-1233/1233 =============== 0/0 100.00 96.59 card JQ394987:1-1234 Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. antibacterial_free_fatty_acids/bicyclomycin/diaminopyrimidine/isoniazid/lincosamide/benzalkonium_chloride/rifamycin/nitroimidazole/nucleoside/macrolide/penam/rhodamine/peptide/fosfomycin/glycylcycline/phenicol/cephalosporin/fluoroquinolone/tetracycline/acridine_dye/oxazolidinone
29 SAMN11840203 contig00011 134538 135170 - CRP 1-633/633 =============== 0/0 100.00 99.05 card AP009048.1:4153664-4154297 CRP is a global regulator that represses MdtEF multidrug efflux pump expression. tetracycline/triclosan/acridine_dye/fluoroquinolone/penam/macrolide/phenicol/monobactam/glycylcycline/aminocoumarin/aminoglycoside/carbapenem/diaminopyrimidine/antibacterial_free_fatty_acids
30 SAMN11840203 contig00012 66296 67462 - ugd 1-1167/1167 =============== 0/0 100.00 96.57 card U00096:2098447-2099614 PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin peptide
31 SAMN11840203 contig00012 123856 125103 + mdtA 1-1248/1248 =============== 0/0 100.00 96.88 card U00096:2154016-2155264 MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. antibacterial_free_fatty_acids/aminoglycoside/diaminopyrimidine/carbapenem/aminocoumarin/phenicol/glycylcycline/monobactam/penam/fluoroquinolone/macrolide/acridine_dye/triclosan/tetracycline
32 SAMN11840203 contig00012 125103 128225 + mdtB 1-3123/3123 =============== 0/0 100.00 96.67 card U00096:2155263-2158386 MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. aminocoumarin/aminoglycoside/diaminopyrimidine/carbapenem/antibacterial_free_fatty_acids/acridine_dye/tetracycline/triclosan/penam/fluoroquinolone/macrolide/phenicol/glycylcycline/monobactam
33 SAMN11840203 contig00012 128226 131303 + mdtC 1-3078/3078 =============== 0/0 100.00 96.82 card U00096:2158386-2161464 MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. diaminopyrimidine/carbapenem/aminoglycoside/antibacterial_free_fatty_acids/aminocoumarin/glycylcycline/monobactam/phenicol/acridine_dye/triclosan/tetracycline/macrolide/fluoroquinolone/penam
34 SAMN11840203 contig00012 132716 134119 + baeS 1-1404/1404 =============== 0/0 100.00 97.65 card AP009048:2165013-2166417 BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. aminocoumarin/carbapenem/diaminopyrimidine/aminoglycoside/antibacterial_free_fatty_acids/tetracycline/triclosan/acridine_dye/macrolide/fluoroquinolone/penam/monobactam/glycylcycline/phenicol
35 SAMN11840203 contig00012 134116 134837 + baeR 1-722/723 =============== 0/0 99.86 98.20 card AP009048.1:2166413-2167136 BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. phenicol/monobactam/glycylcycline/tetracycline/triclosan/acridine_dye/penam/fluoroquinolone/macrolide/aminoglycoside/carbapenem/diaminopyrimidine/antibacterial_free_fatty_acids/aminocoumarin
36 SAMN11840203 contig00014 128967 129623 - QnrS1 1-657/657 =============== 0/0 100.00 100.00 card DQ485529.1:1-658 QnrS1 is a plasmid-mediated quinolone resistance protein found in Shigella flexneri fluoroquinolone
37 SAMN11840203 contig00015 102091 103284 + Escherichia_coli_acrA 1-1194/1194 =============== 0/0 100.00 99.25 card U00096.3:484426-485620 AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. rifamycin/macrolide/penam/diaminopyrimidine/antibacterial_free_fatty_acids/glycylcycline/monobactam/phenicol/acridine_dye/tetracycline/triclosan/cephalosporin/fluoroquinolone/carbapenem/aminoglycoside/aminocoumarin
38 SAMN11840203 contig00015 103307 106456 + acrB 1-3150/3150 =============== 0/0 100.00 99.05 card U00096.3:481254-484404 Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. antibacterial_free_fatty_acids/diaminopyrimidine/rifamycin/penam/macrolide/aminoglycoside/carbapenem/aminocoumarin/phenicol/monobactam/glycylcycline/fluoroquinolone/cephalosporin/tetracycline/triclosan/acridine_dye
39 SAMN11840203 contig00018 22463 23836 + cpxA 1-1374/1374 =============== 0/0 100.00 98.62 card BA000007.3:4903689-4905063 CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. acridine_dye/tetracycline/triclosan/macrolide/fluoroquinolone/penam/glycylcycline/monobactam/phenicol/aminocoumarin/diaminopyrimidine/carbapenem/aminoglycoside/antibacterial_free_fatty_acids
40 SAMN11840203 contig00023 327 1559 + mdtM 1-1233/1233 =============== 0/0 100.00 96.51 card U00096.3:4567287-4568520 Multidrug resistance protein MdtM nitroimidazole/rifamycin/nucleoside/penam/macrolide/bicyclomycin/antibacterial_free_fatty_acids/diaminopyrimidine/benzalkonium_chloride/lincosamide/isoniazid/fosfomycin/phenicol/glycylcycline/fluoroquinolone/cephalosporin/oxazolidinone/acridine_dye/tetracycline/rhodamine/peptide
41 SAMN11840203 contig00027 49570 50727 + mdtE 1-1158/1158 =============== 0/0 100.00 98.79 card AP009048.1:3980026-3981184 MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. glycylcycline/monobactam/phenicol/acridine_dye/tetracycline/triclosan/macrolide/fluoroquinolone/penam/diaminopyrimidine/carbapenem/aminoglycoside/antibacterial_free_fatty_acids/aminocoumarin
42 SAMN11840203 contig00027 50752 53865 + mdtF 1-3114/3114 =============== 0/0 100.00 98.49 card U00096:3660414-3663528 MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. triclosan/tetracycline/acridine_dye/macrolide/fluoroquinolone/penam/monobactam/glycylcycline/phenicol/aminocoumarin/carbapenem/diaminopyrimidine/aminoglycoside/antibacterial_free_fatty_acids
43 SAMN11840203 contig00027 54228 54956 - gadW 1-729/729 =============== 0/0 100.00 95.61 card CP015085.1:2551712-2552441 GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. phenicol/monobactam/glycylcycline/penam/fluoroquinolone/macrolide/triclosan/tetracycline/acridine_dye/antibacterial_free_fatty_acids/aminoglycoside/carbapenem/diaminopyrimidine/aminocoumarin
44 SAMN11840203 contig00027 55325 56149 - gadX 1-825/825 =============== 0/0 100.00 94.30 card AP009048.1:3974605-3975430 GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. aminoglycoside/diaminopyrimidine/carbapenem/antibacterial_free_fatty_acids/aminocoumarin/phenicol/glycylcycline/monobactam/acridine_dye/tetracycline/triclosan/penam/fluoroquinolone/macrolide
45 SAMN11840203 contig00031 3563 5101 - emrB 1-1539/1539 =============== 0/0 100.00 97.99 card U00096:2812616-2814155 emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. rhodamine/peptide/fosfomycin/glycylcycline/phenicol/cephalosporin/fluoroquinolone/tetracycline/acridine_dye/oxazolidinone/antibacterial_free_fatty_acids/bicyclomycin/diaminopyrimidine/lincosamide/isoniazid/benzalkonium_chloride/rifamycin/nitroimidazole/nucleoside/macrolide/penam
46 SAMN11840203 contig00031 5118 6290 - emrA 1-1173/1173 =============== 0/0 100.00 97.95 card AP009048:2810083-2811256 EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. benzalkonium_chloride/isoniazid/lincosamide/diaminopyrimidine/bicyclomycin/antibacterial_free_fatty_acids/penam/macrolide/nucleoside/nitroimidazole/rifamycin/peptide/rhodamine/acridine_dye/oxazolidinone/tetracycline/fluoroquinolone/cephalosporin/phenicol/glycylcycline/fosfomycin
47 SAMN11840203 contig00031 6417 6947 - emrR 1-531/531 =============== 0/0 100.00 99.44 card U00096.3:2810770-2811301 EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. rifamycin/nitroimidazole/nucleoside/macrolide/penam/bicyclomycin/antibacterial_free_fatty_acids/diaminopyrimidine/lincosamide/isoniazid/benzalkonium_chloride/fosfomycin/glycylcycline/phenicol/cephalosporin/fluoroquinolone/oxazolidinone/acridine_dye/tetracycline/rhodamine/peptide
48 SAMN11840203 contig00033 25605 26909 + Escherichia_coli_ampC1_beta-lactamase 1-1305/1305 =============== 0/0 100.00 96.02 card FN649414.1:2765051-2766356 An ampC-like beta-lactamase identified from Escherichia coli. cephalosporin/penam
49 SAMN11840203 contig00040 7921 8598 + kdpE 1-678/678 =============== 0/0 100.00 95.43 card U00096.3:721056-721734 kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. aminoglycoside
50 SAMN11840203 contig00041 22681 23033 - Nocardia_rifampin_resistant_beta-subunit_of_RNA_polymerase_(rpoB2) 2980-3332/3489 ......../...=== 6/10 9.97 75.70 card AP006618.1:4835200-4838689 Due to gene duplication the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance. rifamycin
51 SAMN11840203 contig00046 459 1334 - CTX-M-15 1-876/876 =============== 0/0 100.00 100.00 card AY044436:1436-2312 CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family cephalosporin
52 SAMN11840203 contig00057 1194 2033 - sul1 1-840/840 =============== 0/0 100.00 100.00 card JF969163:1054-1894 Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. sulfonamide
53 SAMN11840203 contig00057 3685 4341 - QnrA1 1-657/657 =============== 0/0 100.00 99.85 card DQ831141:8922-9579 QnrA1 is a plasmid-mediated quinolone resistance protein found in Klebsiella pneumoniae fluoroquinolone
54 SAMN11840203 contig00063 3595 4455 - SHV-134 1-861/861 =============== 0/0 100.00 99.88 card HM559945:1-862 SHV-134 is an extended-spectrum beta-lactamase. carbapenem/penam/cephalosporin
55 SAMN11840203 contig00065 1 85 - TEM-101 1-85/861 ==............. 0/0 9.87 100.00 card AF495873:1-862 TEM-101 is an extended-spectrum beta-lactamase found in E. coli. monobactam/penem/cephalosporin/penam
56 SAMN11840203 contig00065 785 1609 - OXA-9 1-825/825 =============== 0/0 100.00 100.00 card M55547:1-826 OXA-9 is a beta-lactamase found in Klebsiella pneumoniae. cephalosporin/penam
57 SAMN11840203 contig00065 1669 2470 - ANT(3'')-IIa 168-972/972 ..======/====== 1/3 82.51 99.25 card X02340.1:223-1195 ANT(3'')-IIa is a aminoglycoside nucleotidyltransferase identified in Acinetobacter spp. via horizontal gene transfer mechanisms. aminoglycoside
58 SAMN11840203 contig00065 2363 3113 - AAC(6')-Ib7 234-980/980 ...=====/====== 2/4 76.22 96.67 card Y11946.1:1-981 AAC(6')-Ib7 is a plasmid-encoded aminoglycoside acetyltransferase in E. cloacae and C. freundii aminoglycoside
59 SAMN11840203 contig00081 26 823 + OXA-48 1-798/798 =============== 0/0 100.00 100.00 card AY236073:2188-2986 OXA-48 is a beta-lactamase found in Klebsiella pneumoniae penam/cephalosporin
60 SAMN11840203 contig00104 1 843 + TEM-1 19-861/861 =============== 0/0 97.91 99.88 card AL513383:161911-162772 TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. penam/cephalosporin/penem/monobactam
61 SAMN11840203 contig00192 1 85 - TEM-1 1-85/861 ==............. 0/0 9.87 100.00 card AL513383:161911-162772 TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. penam/cephalosporin/penem/monobactam