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author | rdaveau |
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date | Fri, 29 Jun 2012 10:20:55 -0400 |
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## What is gfap ? The Genomic and Functional Annotation Pipeline (gfap) consists in a set of perl and R tools that aim at annotating human genetic SNVs/InDels identified by 2nd-generation sequencing technologies. ## How does it work ? gfap starts with a samtools-formatted VCF-file i.e. the DP4-tag from the INFO field is mandatory. gfap performs its annotation in a 4-steps linear procedure i.e.: 1> SAMVCF.data.parser 2> Known.variants.finder 3> Map.to.genomic.features 4> Map.to.dbNSFP.features ## Pre-requisites In gfap_r1.0_samvcf_data_parser.pl LINE 13 the $rbin assumes that your R binary is set to /usr/bin/R So, you will have to properly edit and reset this $rbin if R is installed elsewhere on your system.