Mercurial > repos > rnateam > cofold
diff rna_turner1999.par @ 0:76d9140e8fa5 draft
Imported from capsule None
| author | bjoern-gruening |
|---|---|
| date | Fri, 13 Feb 2015 05:33:32 -0500 |
| parents | |
| children |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/rna_turner1999.par Fri Feb 13 05:33:32 2015 -0500 @@ -0,0 +1,9899 @@ +## RNAfold parameter file v2.0 + +# stack +/* CG GC GU UG AU UA @ */ + -240 -330 -210 -140 -210 -210 0 + -330 -340 -250 -150 -220 -240 0 + -210 -250 130 DEF -140 -130 0 + -140 -150 DEF 30 -60 -100 0 + -210 -220 -140 -60 -110 -90 0 + -210 -240 -130 -100 -90 -130 0 + 0 0 0 0 0 0 0 + +# stack_enthalpies +/* CG GC GU UG AU UA @ */ + -1060 -1340 -1210 -560 -1050 -1040 0 + -1340 -1490 -1260 -830 -1140 -1240 0 + -1210 -1260 -1460 -1350 -880 -1280 0 + -560 -830 -1350 -930 -320 -700 0 + -1050 -1140 -880 -320 -940 -680 0 + -1040 -1240 -1280 -700 -680 -770 0 + 0 0 0 0 0 0 0 + +# mismatch_hairpin + 0 0 0 0 0 + -90 -150 -150 -140 -180 + -90 -100 -90 -290 -80 + -90 -220 -200 -160 -110 + -90 -170 -140 -180 -200 + 0 0 0 0 0 + -70 -110 -150 -130 -210 + -70 -110 -70 -240 DEF + -70 -240 -290 -140 -120 + -70 -190 -100 -220 -150 + 0 0 0 0 0 + 0 20 DEF -30 -30 + 0 -10 -20 -150 -20 + 0 -90 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550 290 250 240 480 + 550 180 140 120 480 + 550 480 480 480 480 +/* UA.C..GC */ + 550 550 550 550 550 + 550 310 300 480 300 + 550 300 330 480 300 + 550 480 480 480 480 + 550 330 270 480 300 +/* UA.G..GC */ + 550 550 550 550 550 + 550 250 480 160 480 + 550 480 480 480 480 + 550 160 480 300 480 + 550 480 480 480 480 +/* UA.U..GC */ + 550 550 550 550 550 + 550 480 480 480 480 + 550 480 300 480 210 + 550 480 480 480 480 + 550 480 250 480 200 +/* UA.@..GU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* UA.A..GU */ + 550 550 550 550 550 + 550 390 370 310 550 + 550 360 320 310 550 + 550 250 210 190 550 + 550 550 550 550 550 +/* UA.C..GU */ + 550 550 550 550 550 + 550 380 370 550 370 + 550 370 400 550 370 + 550 550 550 550 550 + 550 400 340 550 370 +/* UA.G..GU */ + 550 550 550 550 550 + 550 320 550 230 550 + 550 550 550 550 550 + 550 230 550 370 550 + 550 550 550 550 550 +/* UA.U..GU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 370 550 280 + 550 550 550 550 550 + 550 550 320 550 270 +/* UA.@..UG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* UA.A..UG */ + 550 550 550 550 550 + 550 390 370 310 550 + 550 360 320 310 550 + 550 250 210 190 550 + 550 550 550 550 550 +/* UA.C..UG */ + 550 550 550 550 550 + 550 380 370 550 370 + 550 370 400 550 370 + 550 550 550 550 550 + 550 400 340 550 370 +/* UA.G..UG */ + 550 550 550 550 550 + 550 320 550 230 550 + 550 550 550 550 550 + 550 230 550 370 550 + 550 550 550 550 550 +/* UA.U..UG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 370 550 280 + 550 550 550 550 550 + 550 550 320 550 270 +/* UA.@..AU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* UA.A..AU */ + 550 550 550 550 550 + 550 390 370 310 550 + 550 360 320 310 550 + 550 250 210 190 550 + 550 550 550 550 550 +/* UA.C..AU */ + 550 550 550 550 550 + 550 380 370 550 370 + 550 370 400 550 370 + 550 550 550 550 550 + 550 400 340 550 370 +/* UA.G..AU */ + 550 550 550 550 550 + 550 320 550 230 550 + 550 550 550 550 550 + 550 230 550 370 550 + 550 550 550 550 550 +/* UA.U..AU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 370 550 280 + 550 550 550 550 550 + 550 550 320 550 270 +/* UA.@..UA */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* UA.A..UA */ + 550 550 550 550 550 + 550 390 370 310 550 + 550 360 320 310 550 + 550 250 210 190 550 + 550 550 550 550 550 +/* UA.C..UA */ + 550 550 550 550 550 + 550 380 370 550 370 + 550 370 400 550 370 + 550 550 550 550 550 + 550 400 340 550 370 +/* UA.G..UA */ + 550 550 550 550 550 + 550 320 550 230 550 + 550 550 550 550 550 + 550 230 550 370 550 + 550 550 550 550 550 +/* UA.U..UA */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 370 550 280 + 550 550 550 550 550 + 550 550 320 550 270 +/* UA.@.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* UA.A.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* UA.C.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* UA.G.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* UA.U.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.@..CG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.A..CG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.C..CG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.G..CG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.U..CG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.@..GC */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.A..GC */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.C..GC */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.G..GC */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.U..GC */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.@..GU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.A..GU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.C..GU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.G..GU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.U..GU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.@..UG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.A..UG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.C..UG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.G..UG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.U..UG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.@..AU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.A..AU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.C..AU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.G..AU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.U..AU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.@..UA */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.A..UA */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.C..UA */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.G..UA */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.U..UA */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.@.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.A.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.C.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.G.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.U.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + +# int21_enthalpies +/* CG.@..CG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A..CG */ + DEF -1029 -949 -1029 -1029 + -1079 -2058 -1978 -2058 -2058 + -569 -1548 -1468 -1548 -1548 + -989 -1968 -1888 -1968 -1968 + -859 -1838 -1758 -1838 -1838 +/* CG.C..CG */ + DEF -519 -449 -519 -669 + -999 -1468 -1398 -1468 -1618 + -499 -968 -898 -968 -1118 + -989 -1458 -1388 -1458 -1608 + -789 -1258 -1188 -1258 -1408 +/* CG.G..CG */ + DEF -939 -939 -939 -939 + -1079 -1968 -1968 -1968 -1968 + -569 -1458 -1458 -1458 -1458 + -989 -1878 -1878 -1878 -1878 + -859 -1748 -1748 -1748 -1748 +/* CG.U..CG */ + DEF -809 -739 -809 -859 + -1079 -1838 -1768 -1838 -1888 + -719 -1478 -1408 -1478 -1528 + -989 -1748 -1678 -1748 -1798 + -909 -1668 -1598 -1668 -1718 +/* CG.@..GC */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A..GC */ + DEF -1029 -949 -1029 -1029 + -569 -1548 -1468 -1548 -1548 + -769 -1748 -1668 -1748 -1748 + -759 -1738 -1658 -1738 -1738 + -549 -1528 -1448 -1528 -1528 +/* CG.C..GC */ + DEF -519 -449 -519 -669 + -929 -1398 -1328 -1398 -1548 + -359 -828 -758 -828 -978 + -789 -1258 -1188 -1258 -1408 + -549 -1018 -948 -1018 -1168 +/* CG.G..GC */ + DEF -939 -939 -939 -939 + -609 -1498 -1498 -1498 -1498 + -359 -1248 -1248 -1248 -1248 + -669 -1558 -1558 -1558 -1558 + -549 -1438 -1438 -1438 -1438 +/* CG.U..GC */ + DEF -809 -739 -809 -859 + -929 -1688 -1618 -1688 -1738 + -439 -1198 -1128 -1198 -1248 + -789 -1548 -1478 -1548 -1598 + -619 -1378 -1308 -1378 -1428 +/* CG.@..GU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A..GU */ + DEF -1029 -949 -1029 -1029 + -479 -1458 -1378 -1458 -1458 + -309 -1288 -1208 -1288 -1288 + -389 -1368 -1288 -1368 -1368 + -379 -1358 -1278 -1358 -1358 +/* CG.C..GU */ + DEF -519 -449 -519 -669 + -649 -1118 -1048 -1118 -1268 + -289 -758 -688 -758 -908 + -739 -1208 -1138 -1208 -1358 + -379 -848 -778 -848 -998 +/* CG.G..GU */ + DEF -939 -939 -939 -939 + -649 -1538 -1538 -1538 -1538 + -289 -1178 -1178 -1178 -1178 + -739 -1628 -1628 -1628 -1628 + -379 -1268 -1268 -1268 -1268 +/* CG.U..GU */ + DEF -809 -739 -809 -859 + -649 -1408 -1338 -1408 -1458 + -289 -1048 -978 -1048 -1098 + -739 -1498 -1428 -1498 -1548 + -379 -1138 -1068 -1138 -1188 +/* CG.@..UG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A..UG */ + DEF -1029 -949 -1029 -1029 + -769 -1748 -1668 -1748 -1748 + -529 -1508 -1428 -1508 -1508 + -709 -1688 -1608 -1688 -1688 + -599 -1578 -1498 -1578 -1578 +/* CG.C..UG */ + DEF -519 -449 -519 -669 + -839 -1308 -1238 -1308 -1458 + -529 -998 -928 -998 -1148 + -859 -1328 -1258 -1328 -1478 + -489 -958 -888 -958 -1108 +/* CG.G..UG */ + DEF -939 -939 -939 -939 + -1009 -1898 -1898 -1898 -1898 + -409 -1298 -1298 -1298 -1298 + -969 -1858 -1858 -1858 -1858 + -599 -1488 -1488 -1488 -1488 +/* CG.U..UG */ + DEF -809 -739 -809 -859 + -859 -1618 -1548 -1618 -1668 + -529 -1288 -1218 -1288 -1338 + -859 -1618 -1548 -1618 -1668 + -409 -1168 -1098 -1168 -1218 +/* CG.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A..AU */ + DEF -1029 -949 -1029 -1029 + -479 -1458 -1378 -1458 -1458 + -309 -1288 -1208 -1288 -1288 + -389 -1368 -1288 -1368 -1368 + -379 -1358 -1278 -1358 -1358 +/* CG.C..AU */ + DEF -519 -449 -519 -669 + -649 -1118 -1048 -1118 -1268 + -289 -758 -688 -758 -908 + -739 -1208 -1138 -1208 -1358 + -379 -848 -778 -848 -998 +/* CG.G..AU */ + DEF -939 -939 -939 -939 + -649 -1538 -1538 -1538 -1538 + -289 -1178 -1178 -1178 -1178 + -739 -1628 -1628 -1628 -1628 + -379 -1268 -1268 -1268 -1268 +/* CG.U..AU */ + DEF -809 -739 -809 -859 + -649 -1408 -1338 -1408 -1458 + -289 -1048 -978 -1048 -1098 + -739 -1498 -1428 -1498 -1548 + -379 -1138 -1068 -1138 -1188 +/* CG.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A..UA */ + DEF -1029 -949 -1029 -1029 + -449 -1428 -1348 -1428 -1428 + -479 -1458 -1378 -1458 -1458 + -429 -1408 -1328 -1408 -1408 + -329 -1308 -1228 -1308 -1308 +/* CG.C..UA */ + DEF -519 -449 -519 -669 + -679 -1148 -1078 -1148 -1298 + -559 -1028 -958 -1028 -1178 + -729 -1198 -1128 -1198 -1348 + -189 -658 -588 -658 -808 +/* CG.G..UA */ + DEF -939 -939 -939 -939 + -939 -1828 -1828 -1828 -1828 + -249 -1138 -1138 -1138 -1138 + -939 -1828 -1828 -1828 -1828 + -329 -1218 -1218 -1218 -1218 +/* CG.U..UA */ + DEF -809 -739 -809 -859 + -639 -1398 -1328 -1398 -1448 + -229 -988 -918 -988 -1038 + -729 -1488 -1418 -1488 -1538 + -190 -949 -879 -949 -999 +/* CG.@.. @ */ + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A.. @ */ + -100 -1079 -999 -1079 -1079 + -100 -1079 -999 -1079 -1079 + -100 -1079 -999 -1079 -1079 + -100 -1079 -999 -1079 -1079 + -100 -1079 -999 -1079 -1079 +/* CG.C.. @ */ + -100 -569 -499 -569 -719 + -100 -569 -499 -569 -719 + -100 -569 -499 -569 -719 + -100 -569 -499 -569 -719 + -100 -569 -499 -569 -719 +/* CG.G.. @ */ + -100 -989 -989 -989 -989 + -100 -989 -989 -989 -989 + -100 -989 -989 -989 -989 + -100 -989 -989 -989 -989 + -100 -989 -989 -989 -989 +/* CG.U.. @ */ + -100 -859 -789 -859 -909 + -100 -859 -789 -859 -909 + -100 -859 -789 -859 -909 + -100 -859 -789 -859 -909 + -100 -859 -789 -859 -909 +/* GC.@..CG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A..CG */ + DEF -519 -879 -559 -879 + -1079 -1548 -1908 -1588 -1908 + -569 -1038 -1398 -1078 -1398 + -989 -1458 -1818 -1498 -1818 + -859 -1328 -1688 -1368 -1688 +/* GC.C..CG */ + DEF -719 -309 -309 -389 + -999 -1668 -1258 -1258 -1338 + -499 -1168 -758 -758 -838 + -989 -1658 -1248 -1248 -1328 + -789 -1458 -1048 -1048 -1128 +/* GC.G..CG */ + DEF -709 -739 -619 -739 + -1079 -1738 -1768 -1648 -1768 + -569 -1228 -1258 -1138 -1258 + -989 -1648 -1678 -1558 -1678 + -859 -1518 -1548 -1428 -1548 +/* GC.U..CG */ + DEF -499 -499 -499 -569 + -1079 -1528 -1528 -1528 -1598 + -719 -1168 -1168 -1168 -1238 + -989 -1438 -1438 -1438 -1508 + -909 -1358 -1358 -1358 -1428 +/* GC.@..GC */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A..GC */ + DEF -519 -879 -559 -879 + -569 -1038 -1398 -1078 -1398 + -769 -1238 -1598 -1278 -1598 + -759 -1228 -1588 -1268 -1588 + -549 -1018 -1378 -1058 -1378 +/* GC.C..GC */ + DEF -719 -309 -309 -389 + -929 -1598 -1188 -1188 -1268 + -359 -1028 -618 -618 -698 + -789 -1458 -1048 -1048 -1128 + -549 -1218 -808 -808 -888 +/* GC.G..GC */ + DEF -709 -739 -619 -739 + -609 -1268 -1298 -1178 -1298 + -359 -1018 -1048 -928 -1048 + -669 -1328 -1358 -1238 -1358 + -549 -1208 -1238 -1118 -1238 +/* GC.U..GC */ + DEF -499 -499 -499 -569 + -929 -1378 -1378 -1378 -1448 + -439 -888 -888 -888 -958 + -789 -1238 -1238 -1238 -1308 + -619 -1068 -1068 -1068 -1138 +/* GC.@..GU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A..GU */ + DEF -519 -879 -559 -879 + -479 -948 -1308 -988 -1308 + -309 -778 -1138 -818 -1138 + -389 -858 -1218 -898 -1218 + -379 -848 -1208 -888 -1208 +/* GC.C..GU */ + DEF -719 -309 -309 -389 + -649 -1318 -908 -908 -988 + -289 -958 -548 -548 -628 + -739 -1408 -998 -998 -1078 + -379 -1048 -638 -638 -718 +/* GC.G..GU */ + DEF -709 -739 -619 -739 + -649 -1308 -1338 -1218 -1338 + -289 -948 -978 -858 -978 + -739 -1398 -1428 -1308 -1428 + -379 -1038 -1068 -948 -1068 +/* GC.U..GU */ + DEF -499 -499 -499 -569 + -649 -1098 -1098 -1098 -1168 + -289 -738 -738 -738 -808 + -739 -1188 -1188 -1188 -1258 + -379 -828 -828 -828 -898 +/* GC.@..UG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A..UG */ + DEF -519 -879 -559 -879 + -769 -1238 -1598 -1278 -1598 + -529 -998 -1358 -1038 -1358 + -709 -1178 -1538 -1218 -1538 + -599 -1068 -1428 -1108 -1428 +/* GC.C..UG */ + DEF -719 -309 -309 -389 + -839 -1508 -1098 -1098 -1178 + -529 -1198 -788 -788 -868 + -859 -1528 -1118 -1118 -1198 + -489 -1158 -748 -748 -828 +/* GC.G..UG */ + DEF -709 -739 -619 -739 + -1009 -1668 -1698 -1578 -1698 + -409 -1068 -1098 -978 -1098 + -969 -1628 -1658 -1538 -1658 + -599 -1258 -1288 -1168 -1288 +/* GC.U..UG */ + DEF -499 -499 -499 -569 + -859 -1308 -1308 -1308 -1378 + -529 -978 -978 -978 -1048 + -859 -1308 -1308 -1308 -1378 + -409 -858 -858 -858 -928 +/* GC.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A..AU */ + DEF -519 -879 -559 -879 + -479 -948 -1308 -988 -1308 + -309 -778 -1138 -818 -1138 + -389 -858 -1218 -898 -1218 + -379 -848 -1208 -888 -1208 +/* GC.C..AU */ + DEF -719 -309 -309 -389 + -649 -1318 -908 -908 -988 + -289 -958 -548 -548 -628 + -739 -1408 -998 -998 -1078 + -379 -1048 -638 -638 -718 +/* GC.G..AU */ + DEF -709 -739 -619 -739 + -649 -1308 -1338 -1218 -1338 + -289 -948 -978 -858 -978 + -739 -1398 -1428 -1308 -1428 + -379 -1038 -1068 -948 -1068 +/* GC.U..AU */ + DEF -499 -499 -499 -569 + -649 -1098 -1098 -1098 -1168 + -289 -738 -738 -738 -808 + -739 -1188 -1188 -1188 -1258 + -379 -828 -828 -828 -898 +/* GC.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A..UA */ + DEF -519 -879 -559 -879 + -449 -918 -1278 -958 -1278 + -479 -948 -1308 -988 -1308 + -429 -898 -1258 -938 -1258 + -329 -798 -1158 -838 -1158 +/* GC.C..UA */ + DEF -719 -309 -309 -389 + -679 -1348 -938 -938 -1018 + -559 -1228 -818 -818 -898 + -729 -1398 -988 -988 -1068 + -189 -858 -448 -448 -528 +/* GC.G..UA */ + DEF -709 -739 -619 -739 + -939 -1598 -1628 -1508 -1628 + -249 -908 -938 -818 -938 + -939 -1598 -1628 -1508 -1628 + -329 -988 -1018 -898 -1018 +/* GC.U..UA */ + DEF -499 -499 -499 -569 + -639 -1088 -1088 -1088 -1158 + -229 -678 -678 -678 -748 + -729 -1178 -1178 -1178 -1248 + -190 -639 -639 -639 -709 +/* GC.@.. @ */ + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A.. @ */ + -100 -569 -929 -609 -929 + -100 -569 -929 -609 -929 + -100 -569 -929 -609 -929 + -100 -569 -929 -609 -929 + -100 -569 -929 -609 -929 +/* GC.C.. @ */ + -100 -769 -359 -359 -439 + -100 -769 -359 -359 -439 + -100 -769 -359 -359 -439 + -100 -769 -359 -359 -439 + -100 -769 -359 -359 -439 +/* GC.G.. @ */ + -100 -759 -789 -669 -789 + -100 -759 -789 -669 -789 + -100 -759 -789 -669 -789 + -100 -759 -789 -669 -789 + -100 -759 -789 -669 -789 +/* GC.U.. @ */ + -100 -549 -549 -549 -619 + -100 -549 -549 -549 -619 + -100 -549 -549 -549 -619 + -100 -549 -549 -549 -619 + -100 -549 -549 -549 -619 +/* GU.@..CG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A..CG */ + DEF -429 -599 -599 -599 + -1079 -1458 -1628 -1628 -1628 + -569 -948 -1118 -1118 -1118 + -989 -1368 -1538 -1538 -1538 + -859 -1238 -1408 -1408 -1408 +/* GU.C..CG */ + DEF -259 -239 -239 -239 + -999 -1208 -1188 -1188 -1188 + -499 -708 -688 -688 -688 + -989 -1198 -1178 -1178 -1178 + -789 -998 -978 -978 -978 +/* GU.G..CG */ + DEF -339 -689 -689 -689 + -1079 -1368 -1718 -1718 -1718 + -569 -858 -1208 -1208 -1208 + -989 -1278 -1628 -1628 -1628 + -859 -1148 -1498 -1498 -1498 +/* GU.U..CG */ + DEF -329 -329 -329 -329 + -1079 -1358 -1358 -1358 -1358 + -719 -998 -998 -998 -998 + -989 -1268 -1268 -1268 -1268 + -909 -1188 -1188 -1188 -1188 +/* GU.@..GC */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A..GC */ + DEF -429 -599 -599 -599 + -569 -948 -1118 -1118 -1118 + -769 -1148 -1318 -1318 -1318 + -759 -1138 -1308 -1308 -1308 + -549 -928 -1098 -1098 -1098 +/* GU.C..GC */ + DEF -259 -239 -239 -239 + -929 -1138 -1118 -1118 -1118 + -359 -568 -548 -548 -548 + -789 -998 -978 -978 -978 + -549 -758 -738 -738 -738 +/* GU.G..GC */ + DEF -339 -689 -689 -689 + -609 -898 -1248 -1248 -1248 + -359 -648 -998 -998 -998 + -669 -958 -1308 -1308 -1308 + -549 -838 -1188 -1188 -1188 +/* GU.U..GC */ + DEF -329 -329 -329 -329 + -929 -1208 -1208 -1208 -1208 + -439 -718 -718 -718 -718 + -789 -1068 -1068 -1068 -1068 + -619 -898 -898 -898 -898 +/* GU.@..GU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A..GU */ + DEF -429 -599 -599 -599 + -479 -858 -1028 -1028 -1028 + -309 -688 -858 -858 -858 + -389 -768 -938 -938 -938 + -379 -758 -928 -928 -928 +/* GU.C..GU */ + DEF -259 -239 -239 -239 + -649 -858 -838 -838 -838 + -289 -498 -478 -478 -478 + -739 -948 -928 -928 -928 + -379 -588 -568 -568 -568 +/* GU.G..GU */ + DEF -339 -689 -689 -689 + -649 -938 -1288 -1288 -1288 + -289 -578 -928 -928 -928 + -739 -1028 -1378 -1378 -1378 + -379 -668 -1018 -1018 -1018 +/* GU.U..GU */ + DEF -329 -329 -329 -329 + -649 -928 -928 -928 -928 + -289 -568 -568 -568 -568 + -739 -1018 -1018 -1018 -1018 + -379 -658 -658 -658 -658 +/* GU.@..UG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A..UG */ + DEF -429 -599 -599 -599 + -769 -1148 -1318 -1318 -1318 + -529 -908 -1078 -1078 -1078 + -709 -1088 -1258 -1258 -1258 + -599 -978 -1148 -1148 -1148 +/* GU.C..UG */ + DEF -259 -239 -239 -239 + -839 -1048 -1028 -1028 -1028 + -529 -738 -718 -718 -718 + -859 -1068 -1048 -1048 -1048 + -489 -698 -678 -678 -678 +/* GU.G..UG */ + DEF -339 -689 -689 -689 + -1009 -1298 -1648 -1648 -1648 + -409 -698 -1048 -1048 -1048 + -969 -1258 -1608 -1608 -1608 + -599 -888 -1238 -1238 -1238 +/* GU.U..UG */ + DEF -329 -329 -329 -329 + -859 -1138 -1138 -1138 -1138 + -529 -808 -808 -808 -808 + -859 -1138 -1138 -1138 -1138 + -409 -688 -688 -688 -688 +/* GU.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A..AU */ + DEF -429 -599 -599 -599 + -479 -858 -1028 -1028 -1028 + -309 -688 -858 -858 -858 + -389 -768 -938 -938 -938 + -379 -758 -928 -928 -928 +/* GU.C..AU */ + DEF -259 -239 -239 -239 + -649 -858 -838 -838 -838 + -289 -498 -478 -478 -478 + -739 -948 -928 -928 -928 + -379 -588 -568 -568 -568 +/* GU.G..AU */ + DEF -339 -689 -689 -689 + -649 -938 -1288 -1288 -1288 + -289 -578 -928 -928 -928 + -739 -1028 -1378 -1378 -1378 + -379 -668 -1018 -1018 -1018 +/* GU.U..AU */ + DEF -329 -329 -329 -329 + -649 -928 -928 -928 -928 + -289 -568 -568 -568 -568 + -739 -1018 -1018 -1018 -1018 + -379 -658 -658 -658 -658 +/* GU.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A..UA */ + DEF -429 -599 -599 -599 + -449 -828 -998 -998 -998 + -479 -858 -1028 -1028 -1028 + -429 -808 -978 -978 -978 + -329 -708 -878 -878 -878 +/* GU.C..UA */ + DEF -259 -239 -239 -239 + -679 -888 -868 -868 -868 + -559 -768 -748 -748 -748 + -729 -938 -918 -918 -918 + -189 -398 -378 -378 -378 +/* GU.G..UA */ + DEF -339 -689 -689 -689 + -939 -1228 -1578 -1578 -1578 + -249 -538 -888 -888 -888 + -939 -1228 -1578 -1578 -1578 + -329 -618 -968 -968 -968 +/* GU.U..UA */ + DEF -329 -329 -329 -329 + -639 -918 -918 -918 -918 + -229 -508 -508 -508 -508 + -729 -1008 -1008 -1008 -1008 + -190 -469 -469 -469 -469 +/* GU.@.. @ */ + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A.. @ */ + -100 -479 -649 -649 -649 + -100 -479 -649 -649 -649 + -100 -479 -649 -649 -649 + -100 -479 -649 -649 -649 + -100 -479 -649 -649 -649 +/* GU.C.. @ */ + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 +/* GU.G.. @ */ + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 +/* GU.U.. @ */ + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 +/* UG.@..CG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A..CG */ + DEF -719 -789 -959 -809 + -1079 -1748 -1818 -1988 -1838 + -569 -1238 -1308 -1478 -1328 + -989 -1658 -1728 -1898 -1748 + -859 -1528 -1598 -1768 -1618 +/* UG.C..CG */ + DEF -479 -479 -359 -479 + -999 -1428 -1428 -1308 -1428 + -499 -928 -928 -808 -928 + -989 -1418 -1418 -1298 -1418 + -789 -1218 -1218 -1098 -1218 +/* UG.G..CG */ + DEF -659 -809 -919 -809 + -1079 -1688 -1838 -1948 -1838 + -569 -1178 -1328 -1438 -1328 + -989 -1598 -1748 -1858 -1748 + -859 -1468 -1618 -1728 -1618 +/* UG.U..CG */ + DEF -549 -439 -549 -359 + -1079 -1578 -1468 -1578 -1388 + -719 -1218 -1108 -1218 -1028 + -989 -1488 -1378 -1488 -1298 + -909 -1408 -1298 -1408 -1218 +/* UG.@..GC */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A..GC */ + DEF -719 -789 -959 -809 + -569 -1238 -1308 -1478 -1328 + -769 -1438 -1508 -1678 -1528 + -759 -1428 -1498 -1668 -1518 + -549 -1218 -1288 -1458 -1308 +/* UG.C..GC */ + DEF -479 -479 -359 -479 + -929 -1358 -1358 -1238 -1358 + -359 -788 -788 -668 -788 + -789 -1218 -1218 -1098 -1218 + -549 -978 -978 -858 -978 +/* UG.G..GC */ + DEF -659 -809 -919 -809 + -609 -1218 -1368 -1478 -1368 + -359 -968 -1118 -1228 -1118 + -669 -1278 -1428 -1538 -1428 + -549 -1158 -1308 -1418 -1308 +/* UG.U..GC */ + DEF -549 -439 -549 -359 + -929 -1428 -1318 -1428 -1238 + -439 -938 -828 -938 -748 + -789 -1288 -1178 -1288 -1098 + -619 -1118 -1008 -1118 -928 +/* UG.@..GU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A..GU */ + DEF -719 -789 -959 -809 + -479 -1148 -1218 -1388 -1238 + -309 -978 -1048 -1218 -1068 + -389 -1058 -1128 -1298 -1148 + -379 -1048 -1118 -1288 -1138 +/* UG.C..GU */ + DEF -479 -479 -359 -479 + -649 -1078 -1078 -958 -1078 + -289 -718 -718 -598 -718 + -739 -1168 -1168 -1048 -1168 + -379 -808 -808 -688 -808 +/* UG.G..GU */ + DEF -659 -809 -919 -809 + -649 -1258 -1408 -1518 -1408 + -289 -898 -1048 -1158 -1048 + -739 -1348 -1498 -1608 -1498 + -379 -988 -1138 -1248 -1138 +/* UG.U..GU */ + DEF -549 -439 -549 -359 + -649 -1148 -1038 -1148 -958 + -289 -788 -678 -788 -598 + -739 -1238 -1128 -1238 -1048 + -379 -878 -768 -878 -688 +/* UG.@..UG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A..UG */ + DEF -719 -789 -959 -809 + -769 -1438 -1508 -1678 -1528 + -529 -1198 -1268 -1438 -1288 + -709 -1378 -1448 -1618 -1468 + -599 -1268 -1338 -1508 -1358 +/* UG.C..UG */ + DEF -479 -479 -359 -479 + -839 -1268 -1268 -1148 -1268 + -529 -958 -958 -838 -958 + -859 -1288 -1288 -1168 -1288 + -489 -918 -918 -798 -918 +/* UG.G..UG */ + DEF -659 -809 -919 -809 + -1009 -1618 -1768 -1878 -1768 + -409 -1018 -1168 -1278 -1168 + -969 -1578 -1728 -1838 -1728 + -599 -1208 -1358 -1468 -1358 +/* UG.U..UG */ + DEF -549 -439 -549 -359 + -859 -1358 -1248 -1358 -1168 + -529 -1028 -918 -1028 -838 + -859 -1358 -1248 -1358 -1168 + -409 -908 -798 -908 -718 +/* UG.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A..AU */ + DEF -719 -789 -959 -809 + -479 -1148 -1218 -1388 -1238 + -309 -978 -1048 -1218 -1068 + -389 -1058 -1128 -1298 -1148 + -379 -1048 -1118 -1288 -1138 +/* UG.C..AU */ + DEF -479 -479 -359 -479 + -649 -1078 -1078 -958 -1078 + -289 -718 -718 -598 -718 + -739 -1168 -1168 -1048 -1168 + -379 -808 -808 -688 -808 +/* UG.G..AU */ + DEF -659 -809 -919 -809 + -649 -1258 -1408 -1518 -1408 + -289 -898 -1048 -1158 -1048 + -739 -1348 -1498 -1608 -1498 + -379 -988 -1138 -1248 -1138 +/* UG.U..AU */ + DEF -549 -439 -549 -359 + -649 -1148 -1038 -1148 -958 + -289 -788 -678 -788 -598 + -739 -1238 -1128 -1238 -1048 + -379 -878 -768 -878 -688 +/* UG.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A..UA */ + DEF -719 -789 -959 -809 + -449 -1118 -1188 -1358 -1208 + -479 -1148 -1218 -1388 -1238 + -429 -1098 -1168 -1338 -1188 + -329 -998 -1068 -1238 -1088 +/* UG.C..UA */ + DEF -479 -479 -359 -479 + -679 -1108 -1108 -988 -1108 + -559 -988 -988 -868 -988 + -729 -1158 -1158 -1038 -1158 + -189 -618 -618 -498 -618 +/* UG.G..UA */ + DEF -659 -809 -919 -809 + -939 -1548 -1698 -1808 -1698 + -249 -858 -1008 -1118 -1008 + -939 -1548 -1698 -1808 -1698 + -329 -938 -1088 -1198 -1088 +/* UG.U..UA */ + DEF -549 -439 -549 -359 + -639 -1138 -1028 -1138 -948 + -229 -728 -618 -728 -538 + -729 -1228 -1118 -1228 -1038 + -190 -689 -579 -689 -499 +/* UG.@.. @ */ + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A.. @ */ + -100 -769 -839 -1009 -859 + -100 -769 -839 -1009 -859 + -100 -769 -839 -1009 -859 + -100 -769 -839 -1009 -859 + -100 -769 -839 -1009 -859 +/* UG.C.. @ */ + -100 -529 -529 -409 -529 + -100 -529 -529 -409 -529 + -100 -529 -529 -409 -529 + -100 -529 -529 -409 -529 + -100 -529 -529 -409 -529 +/* UG.G.. @ */ + -100 -709 -859 -969 -859 + -100 -709 -859 -969 -859 + -100 -709 -859 -969 -859 + -100 -709 -859 -969 -859 + -100 -709 -859 -969 -859 +/* UG.U.. @ */ + -100 -599 -489 -599 -409 + -100 -599 -489 -599 -409 + -100 -599 -489 -599 -409 + -100 -599 -489 -599 -409 + -100 -599 -489 -599 -409 +/* AU.@..CG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..CG */ + DEF -429 -599 -599 -599 + -1079 -1458 -1628 -1628 -1628 + -569 -948 -1118 -1118 -1118 + -989 -1368 -1538 -1538 -1538 + -859 -1238 -1408 -1408 -1408 +/* AU.C..CG */ + DEF -259 -239 -239 -239 + -999 -1208 -1188 -1188 -1188 + -499 -708 -688 -688 -688 + -989 -1198 -1178 -1178 -1178 + -789 -998 -978 -978 -978 +/* AU.G..CG */ + DEF -339 -689 -689 -689 + -1079 -1368 -1718 -1718 -1718 + -569 -858 -1208 -1208 -1208 + -989 -1278 -1628 -1628 -1628 + -859 -1148 -1498 -1498 -1498 +/* AU.U..CG */ + DEF -329 -329 -329 -329 + -1079 -1358 -1358 -1358 -1358 + -719 -998 -998 -998 -998 + -989 -1268 -1268 -1268 -1268 + -909 -1188 -1188 -1188 -1188 +/* AU.@..GC */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..GC */ + DEF -429 -599 -599 -599 + -569 -948 -1118 -1118 -1118 + -769 -1148 -1318 -1318 -1318 + -759 -1138 -1308 -1308 -1308 + -549 -928 -1098 -1098 -1098 +/* AU.C..GC */ + DEF -259 -239 -239 -239 + -929 -1138 -1118 -1118 -1118 + -359 -568 -548 -548 -548 + -789 -998 -978 -978 -978 + -549 -758 -738 -738 -738 +/* AU.G..GC */ + DEF -339 -689 -689 -689 + -609 -898 -1248 -1248 -1248 + -359 -648 -998 -998 -998 + -669 -958 -1308 -1308 -1308 + -549 -838 -1188 -1188 -1188 +/* AU.U..GC */ + DEF -329 -329 -329 -329 + -929 -1208 -1208 -1208 -1208 + -439 -718 -718 -718 -718 + -789 -1068 -1068 -1068 -1068 + -619 -898 -898 -898 -898 +/* AU.@..GU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..GU */ + DEF -429 -599 -599 -599 + -479 -858 -1028 -1028 -1028 + -309 -688 -858 -858 -858 + -389 -768 -938 -938 -938 + -379 -758 -928 -928 -928 +/* AU.C..GU */ + DEF -259 -239 -239 -239 + -649 -858 -838 -838 -838 + -289 -498 -478 -478 -478 + -739 -948 -928 -928 -928 + -379 -588 -568 -568 -568 +/* AU.G..GU */ + DEF -339 -689 -689 -689 + -649 -938 -1288 -1288 -1288 + -289 -578 -928 -928 -928 + -739 -1028 -1378 -1378 -1378 + -379 -668 -1018 -1018 -1018 +/* AU.U..GU */ + DEF -329 -329 -329 -329 + -649 -928 -928 -928 -928 + -289 -568 -568 -568 -568 + -739 -1018 -1018 -1018 -1018 + -379 -658 -658 -658 -658 +/* AU.@..UG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..UG */ + DEF -429 -599 -599 -599 + -769 -1148 -1318 -1318 -1318 + -529 -908 -1078 -1078 -1078 + -709 -1088 -1258 -1258 -1258 + -599 -978 -1148 -1148 -1148 +/* AU.C..UG */ + DEF -259 -239 -239 -239 + -839 -1048 -1028 -1028 -1028 + -529 -738 -718 -718 -718 + -859 -1068 -1048 -1048 -1048 + -489 -698 -678 -678 -678 +/* AU.G..UG */ + DEF -339 -689 -689 -689 + -1009 -1298 -1648 -1648 -1648 + -409 -698 -1048 -1048 -1048 + -969 -1258 -1608 -1608 -1608 + -599 -888 -1238 -1238 -1238 +/* AU.U..UG */ + DEF -329 -329 -329 -329 + -859 -1138 -1138 -1138 -1138 + -529 -808 -808 -808 -808 + -859 -1138 -1138 -1138 -1138 + -409 -688 -688 -688 -688 +/* AU.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..AU */ + DEF -429 -599 -599 -599 + -479 -858 -1028 -1028 -1028 + -309 -688 -858 -858 -858 + -389 -768 -938 -938 -938 + -379 -758 -928 -928 -928 +/* AU.C..AU */ + DEF -259 -239 -239 -239 + -649 -858 -838 -838 -838 + -289 -498 -478 -478 -478 + -739 -948 -928 -928 -928 + -379 -588 -568 -568 -568 +/* AU.G..AU */ + DEF -339 -689 -689 -689 + -649 -938 -1288 -1288 -1288 + -289 -578 -928 -928 -928 + -739 -1028 -1378 -1378 -1378 + -379 -668 -1018 -1018 -1018 +/* AU.U..AU */ + DEF -329 -329 -329 -329 + -649 -928 -928 -928 -928 + -289 -568 -568 -568 -568 + -739 -1018 -1018 -1018 -1018 + -379 -658 -658 -658 -658 +/* AU.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..UA */ + DEF -429 -599 -599 -599 + -449 -828 -998 -998 -998 + -479 -858 -1028 -1028 -1028 + -429 -808 -978 -978 -978 + -329 -708 -878 -878 -878 +/* AU.C..UA */ + DEF -259 -239 -239 -239 + -679 -888 -868 -868 -868 + -559 -768 -748 -748 -748 + -729 -938 -918 -918 -918 + -189 -398 -378 -378 -378 +/* AU.G..UA */ + DEF -339 -689 -689 -689 + -939 -1228 -1578 -1578 -1578 + -249 -538 -888 -888 -888 + -939 -1228 -1578 -1578 -1578 + -329 -618 -968 -968 -968 +/* AU.U..UA */ + DEF -329 -329 -329 -329 + -639 -918 -918 -918 -918 + -229 -508 -508 -508 -508 + -729 -1008 -1008 -1008 -1008 + -190 -469 -469 -469 -469 +/* AU.@.. @ */ + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A.. @ */ + -100 -479 -649 -649 -649 + -100 -479 -649 -649 -649 + -100 -479 -649 -649 -649 + -100 -479 -649 -649 -649 + -100 -479 -649 -649 -649 +/* AU.C.. @ */ + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 +/* AU.G.. @ */ + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 +/* AU.U.. @ */ + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 +/* UA.@..CG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..CG */ + DEF -399 -629 -889 -589 + -1079 -1428 -1658 -1918 -1618 + -569 -918 -1148 -1408 -1108 + -989 -1338 -1568 -1828 -1528 + -859 -1208 -1438 -1698 -1398 +/* UA.C..CG */ + DEF -429 -509 -199 -179 + -999 -1378 -1458 -1148 -1128 + -499 -878 -958 -648 -628 + -989 -1368 -1448 -1138 -1118 + -789 -1168 -1248 -938 -918 +/* UA.G..CG */ + DEF -379 -679 -889 -679 + -1079 -1408 -1708 -1918 -1708 + -569 -898 -1198 -1408 -1198 + -989 -1318 -1618 -1828 -1618 + -859 -1188 -1488 -1698 -1488 +/* UA.U..CG */ + DEF -279 -139 -279 -140 + -1079 -1308 -1168 -1308 -1169 + -719 -948 -808 -948 -809 + -989 -1218 -1078 -1218 -1079 + -909 -1138 -998 -1138 -999 +/* UA.@..GC */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..GC */ + DEF -399 -629 -889 -589 + -569 -918 -1148 -1408 -1108 + -769 -1118 -1348 -1608 -1308 + -759 -1108 -1338 -1598 -1298 + -549 -898 -1128 -1388 -1088 +/* UA.C..GC */ + DEF -429 -509 -199 -179 + -929 -1308 -1388 -1078 -1058 + -359 -738 -818 -508 -488 + -789 -1168 -1248 -938 -918 + -549 -928 -1008 -698 -678 +/* UA.G..GC */ + DEF -379 -679 -889 -679 + -609 -938 -1238 -1448 -1238 + -359 -688 -988 -1198 -988 + -669 -998 -1298 -1508 -1298 + -549 -878 -1178 -1388 -1178 +/* UA.U..GC */ + DEF -279 -139 -279 -140 + -929 -1158 -1018 -1158 -1019 + -439 -668 -528 -668 -529 + -789 -1018 -878 -1018 -879 + -619 -848 -708 -848 -709 +/* UA.@..GU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..GU */ + DEF -399 -629 -889 -589 + -479 -828 -1058 -1318 -1018 + -309 -658 -888 -1148 -848 + -389 -738 -968 -1228 -928 + -379 -728 -958 -1218 -918 +/* UA.C..GU */ + DEF -429 -509 -199 -179 + -649 -1028 -1108 -798 -778 + -289 -668 -748 -438 -418 + -739 -1118 -1198 -888 -868 + -379 -758 -838 -528 -508 +/* UA.G..GU */ + DEF -379 -679 -889 -679 + -649 -978 -1278 -1488 -1278 + -289 -618 -918 -1128 -918 + -739 -1068 -1368 -1578 -1368 + -379 -708 -1008 -1218 -1008 +/* UA.U..GU */ + DEF -279 -139 -279 -140 + -649 -878 -738 -878 -739 + -289 -518 -378 -518 -379 + -739 -968 -828 -968 -829 + -379 -608 -468 -608 -469 +/* UA.@..UG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..UG */ + DEF -399 -629 -889 -589 + -769 -1118 -1348 -1608 -1308 + -529 -878 -1108 -1368 -1068 + -709 -1058 -1288 -1548 -1248 + -599 -948 -1178 -1438 -1138 +/* UA.C..UG */ + DEF -429 -509 -199 -179 + -839 -1218 -1298 -988 -968 + -529 -908 -988 -678 -658 + -859 -1238 -1318 -1008 -988 + -489 -868 -948 -638 -618 +/* UA.G..UG */ + DEF -379 -679 -889 -679 + -1009 -1338 -1638 -1848 -1638 + -409 -738 -1038 -1248 -1038 + -969 -1298 -1598 -1808 -1598 + -599 -928 -1228 -1438 -1228 +/* UA.U..UG */ + DEF -279 -139 -279 -140 + -859 -1088 -948 -1088 -949 + -529 -758 -618 -758 -619 + -859 -1088 -948 -1088 -949 + -409 -638 -498 -638 -499 +/* UA.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..AU */ + DEF -399 -629 -889 -589 + -479 -828 -1058 -1318 -1018 + -309 -658 -888 -1148 -848 + -389 -738 -968 -1228 -928 + -379 -728 -958 -1218 -918 +/* UA.C..AU */ + DEF -429 -509 -199 -179 + -649 -1028 -1108 -798 -778 + -289 -668 -748 -438 -418 + -739 -1118 -1198 -888 -868 + -379 -758 -838 -528 -508 +/* UA.G..AU */ + DEF -379 -679 -889 -679 + -649 -978 -1278 -1488 -1278 + -289 -618 -918 -1128 -918 + -739 -1068 -1368 -1578 -1368 + -379 -708 -1008 -1218 -1008 +/* UA.U..AU */ + DEF -279 -139 -279 -140 + -649 -878 -738 -878 -739 + -289 -518 -378 -518 -379 + -739 -968 -828 -968 -829 + -379 -608 -468 -608 -469 +/* UA.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..UA */ + DEF -399 -629 -889 -589 + -449 -798 -1028 -1288 -988 + -479 -828 -1058 -1318 -1018 + -429 -778 -1008 -1268 -968 + -329 -678 -908 -1168 -868 +/* UA.C..UA */ + DEF -429 -509 -199 -179 + -679 -1058 -1138 -828 -808 + -559 -938 -1018 -708 -688 + -729 -1108 -1188 -878 -858 + -189 -568 -648 -338 -318 +/* UA.G..UA */ + DEF -379 -679 -889 -679 + -939 -1268 -1568 -1778 -1568 + -249 -578 -878 -1088 -878 + -939 -1268 -1568 -1778 -1568 + -329 -658 -958 -1168 -958 +/* UA.U..UA */ + DEF -279 -139 -279 -140 + -639 -868 -728 -868 -729 + -229 -458 -318 -458 -319 + -729 -958 -818 -958 -819 + -190 -419 -279 -419 -280 +/* UA.@.. @ */ + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A.. @ */ + -100 -449 -679 -939 -639 + -100 -449 -679 -939 -639 + -100 -449 -679 -939 -639 + -100 -449 -679 -939 -639 + -100 -449 -679 -939 -639 +/* UA.C.. @ */ + -100 -479 -559 -249 -229 + -100 -479 -559 -249 -229 + -100 -479 -559 -249 -229 + -100 -479 -559 -249 -229 + -100 -479 -559 -249 -229 +/* UA.G.. @ */ + -100 -429 -729 -939 -729 + -100 -429 -729 -939 -729 + -100 -429 -729 -939 -729 + -100 -429 -729 -939 -729 + -100 -429 -729 -939 -729 +/* UA.U.. @ */ + -100 -329 -189 -329 -190 + -100 -329 -189 -329 -190 + -100 -329 -189 -329 -190 + -100 -329 -189 -329 -190 + -100 -329 -189 -329 -190 +/* @.@..CG */ + DEF DEF DEF DEF DEF + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 +/* @.A..CG */ + DEF DEF DEF DEF DEF + -1079 -1079 -1079 -1079 -1079 + -569 -569 -569 -569 -569 + -989 -989 -989 -989 -989 + -859 -859 -859 -859 -859 +/* @.C..CG */ + DEF DEF DEF DEF DEF + -999 -999 -999 -999 -999 + -499 -499 -499 -499 -499 + -989 -989 -989 -989 -989 + -789 -789 -789 -789 -789 +/* @.G..CG */ + DEF DEF DEF DEF DEF + -1079 -1079 -1079 -1079 -1079 + -569 -569 -569 -569 -569 + -989 -989 -989 -989 -989 + -859 -859 -859 -859 -859 +/* @.U..CG */ + DEF DEF DEF DEF DEF + -1079 -1079 -1079 -1079 -1079 + -719 -719 -719 -719 -719 + -989 -989 -989 -989 -989 + -909 -909 -909 -909 -909 +/* @.@..GC */ + DEF DEF DEF DEF DEF + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 +/* @.A..GC */ + DEF DEF DEF DEF DEF + -569 -569 -569 -569 -569 + -769 -769 -769 -769 -769 + -759 -759 -759 -759 -759 + -549 -549 -549 -549 -549 +/* @.C..GC */ + DEF DEF DEF DEF DEF + -929 -929 -929 -929 -929 + -359 -359 -359 -359 -359 + -789 -789 -789 -789 -789 + -549 -549 -549 -549 -549 +/* @.G..GC */ + DEF DEF DEF DEF DEF + -609 -609 -609 -609 -609 + -359 -359 -359 -359 -359 + -669 -669 -669 -669 -669 + -549 -549 -549 -549 -549 +/* @.U..GC */ + DEF DEF DEF DEF DEF + -929 -929 -929 -929 -929 + -439 -439 -439 -439 -439 + -789 -789 -789 -789 -789 + -619 -619 -619 -619 -619 +/* @.@..GU */ + DEF DEF DEF DEF DEF + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 +/* @.A..GU */ + DEF DEF DEF DEF DEF + -479 -479 -479 -479 -479 + -309 -309 -309 -309 -309 + -389 -389 -389 -389 -389 + -379 -379 -379 -379 -379 +/* @.C..GU */ + DEF DEF DEF DEF DEF + -649 -649 -649 -649 -649 + -289 -289 -289 -289 -289 + -739 -739 -739 -739 -739 + -379 -379 -379 -379 -379 +/* @.G..GU */ + DEF DEF DEF DEF DEF + -649 -649 -649 -649 -649 + -289 -289 -289 -289 -289 + -739 -739 -739 -739 -739 + -379 -379 -379 -379 -379 +/* @.U..GU */ + DEF DEF DEF DEF DEF + -649 -649 -649 -649 -649 + -289 -289 -289 -289 -289 + -739 -739 -739 -739 -739 + -379 -379 -379 -379 -379 +/* @.@..UG */ + DEF DEF DEF DEF DEF + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 +/* @.A..UG */ + DEF DEF DEF DEF DEF + -769 -769 -769 -769 -769 + -529 -529 -529 -529 -529 + -709 -709 -709 -709 -709 + -599 -599 -599 -599 -599 +/* @.C..UG */ + DEF DEF DEF DEF DEF + -839 -839 -839 -839 -839 + -529 -529 -529 -529 -529 + -859 -859 -859 -859 -859 + -489 -489 -489 -489 -489 +/* @.G..UG */ + DEF DEF DEF DEF DEF + -1009 -1009 -1009 -1009 -1009 + -409 -409 -409 -409 -409 + -969 -969 -969 -969 -969 + -599 -599 -599 -599 -599 +/* @.U..UG */ + DEF DEF DEF DEF DEF + -859 -859 -859 -859 -859 + -529 -529 -529 -529 -529 + -859 -859 -859 -859 -859 + -409 -409 -409 -409 -409 +/* @.@..AU */ + DEF DEF DEF DEF DEF + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 +/* @.A..AU */ + DEF DEF DEF DEF DEF + -479 -479 -479 -479 -479 + -309 -309 -309 -309 -309 + -389 -389 -389 -389 -389 + -379 -379 -379 -379 -379 +/* @.C..AU */ + DEF DEF DEF DEF DEF + -649 -649 -649 -649 -649 + -289 -289 -289 -289 -289 + -739 -739 -739 -739 -739 + -379 -379 -379 -379 -379 +/* @.G..AU */ + DEF DEF DEF DEF DEF + -649 -649 -649 -649 -649 + -289 -289 -289 -289 -289 + -739 -739 -739 -739 -739 + -379 -379 -379 -379 -379 +/* @.U..AU */ + DEF DEF DEF DEF DEF + -649 -649 -649 -649 -649 + -289 -289 -289 -289 -289 + -739 -739 -739 -739 -739 + -379 -379 -379 -379 -379 +/* @.@..UA */ + DEF DEF DEF DEF DEF + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 +/* @.A..UA */ + DEF DEF DEF DEF DEF + -449 -449 -449 -449 -449 + -479 -479 -479 -479 -479 + -429 -429 -429 -429 -429 + -329 -329 -329 -329 -329 +/* @.C..UA */ + DEF DEF DEF DEF DEF + -679 -679 -679 -679 -679 + -559 -559 -559 -559 -559 + -729 -729 -729 -729 -729 + -189 -189 -189 -189 -189 +/* @.G..UA */ + DEF DEF DEF DEF DEF + -939 -939 -939 -939 -939 + -249 -249 -249 -249 -249 + -939 -939 -939 -939 -939 + -329 -329 -329 -329 -329 +/* @.U..UA */ + DEF DEF DEF DEF DEF + -639 -639 -639 -639 -639 + -229 -229 -229 -229 -229 + -729 -729 -729 -729 -729 + -190 -190 -190 -190 -190 +/* @.@.. @ */ + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 +/* @.A.. @ */ + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 +/* @.C.. @ */ + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 +/* @.G.. @ */ + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 +/* @.U.. @ */ + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + +# int22 +/* CG.AA..CG */ + 130 160 30 200 + 120 150 20 200 + 30 60 -70 200 + 200 200 200 200 +/* CG.AC..CG */ + 160 200 60 200 + 210 180 150 200 + 200 200 200 200 + 190 170 130 200 +/* CG.AG..CG */ + 30 60 -70 200 + 200 200 200 200 + 100 140 0 200 + -40 -110 -60 200 +/* CG.AU..CG */ + 200 200 200 200 + 190 170 130 200 + 110 40 90 200 + 140 80 130 200 +/* CG.CA..CG */ + 120 210 200 190 + 110 140 200 120 + 20 150 200 130 + 200 200 200 200 +/* CG.CC..CG */ + 150 180 200 170 + 140 170 200 150 + 200 200 200 200 + 120 150 200 140 +/* CG.CG..CG */ + 20 150 200 130 + 200 200 200 200 + 90 180 200 170 + -150 -20 200 -40 +/* CG.CU..CG */ + 200 200 200 200 + 120 150 200 140 + 0 130 200 110 + 30 60 200 50 +/* CG.GA..CG */ + 30 200 100 110 + 20 200 90 0 + -70 200 0 90 + 200 200 200 200 +/* CG.GC..CG */ + 60 200 140 40 + 150 200 180 130 + 200 200 200 200 + 130 200 170 110 +/* CG.GG..CG */ + -70 200 0 90 + 200 200 200 200 + 0 200 80 90 + -60 200 -70 -260 +/* CG.GU..CG */ + 200 200 200 200 + 130 200 170 110 + 90 200 90 -110 + 130 200 120 110 +/* CG.UA..CG */ + 200 190 -40 140 + 200 120 -150 30 + 200 130 -60 130 + 200 200 200 200 +/* CG.UC..CG */ + 200 170 -110 80 + 200 150 -20 60 + 200 200 200 200 + 200 140 -40 50 +/* CG.UG..CG */ + 200 130 -60 130 + 200 200 200 200 + 200 170 -70 120 + 200 -40 -420 DEF +/* CG.UU..CG */ + 200 200 200 200 + 200 140 -40 50 + 200 110 -260 110 + 200 50 DEF -40 +/* CG.AA..GC */ + 50 60 0 200 + 110 150 -70 200 + -30 10 -160 200 + 200 200 200 200 +/* CG.AC..GC */ + 110 110 -100 200 + 170 150 -60 200 + 200 200 200 200 + 70 50 20 200 +/* CG.AG..GC */ + 40 50 -70 200 + 200 200 200 200 + 100 140 0 200 + 10 -70 -80 200 +/* CG.AU..GC */ + 200 200 200 200 + 180 150 120 200 + DEF -60 -60 200 + 150 0 90 200 +/* CG.CA..GC */ + 130 220 200 200 + 100 130 200 120 + -70 70 200 40 + 200 200 200 200 +/* CG.CC..GC */ + 100 190 200 110 + 100 130 200 120 + 200 200 200 200 + 0 30 200 170 +/* CG.CG..GC */ + 70 70 200 100 + 200 200 200 200 + 90 180 200 170 + -190 -30 200 -70 +/* CG.CU..GC */ + 200 200 200 200 + 110 140 200 120 + -150 -20 200 -30 + -20 -10 200 20 +/* CG.GA..GC */ + -20 200 110 90 + -40 200 90 0 + -170 200 -90 30 + 200 200 200 200 +/* CG.GC..GC */ + 70 200 80 -10 + 110 200 150 100 + 200 200 200 200 + 20 200 50 0 +/* CG.GG..GC */ + DEF 200 -20 60 + 200 200 200 200 + 0 200 80 90 + -90 200 -100 -300 +/* CG.GU..GC */ + 200 200 200 200 + 120 200 150 100 + -130 200 -60 -240 + 90 200 110 60 +/* CG.UA..GC */ + 200 200 -10 140 + 200 120 -160 30 + 200 40 -160 50 + 200 200 200 200 +/* CG.UC..GC */ + 200 110 -160 30 + 200 120 -60 30 + 200 200 200 200 + 200 20 -160 10 +/* CG.UG..GC */ + 200 50 -60 140 + 200 200 200 200 + 200 170 -70 120 + 200 -70 -440 -100 +/* CG.UU..GC */ + 200 200 200 200 + 200 120 DEF 30 + 200 -10 -410 10 + 200 40 -100 60 +/* CG.AA..GU */ + 200 240 100 200 + 180 210 80 200 + 80 110 -20 200 + 200 200 200 200 +/* CG.AC..GU */ + 190 220 90 200 + 230 210 170 200 + 200 200 200 200 + 230 210 170 200 +/* CG.AG..GU */ + 80 110 -20 200 + 200 200 200 200 + 130 170 30 200 + 60 0 40 200 +/* CG.AU..GU */ + 200 200 200 200 + 230 210 170 200 + 160 90 140 200 + 190 130 180 200 +/* CG.CA..GU */ + 190 280 200 270 + 170 200 200 180 + 70 200 200 180 + 200 200 200 200 +/* CG.CC..GU */ + 180 210 200 190 + 160 190 200 180 + 200 200 200 200 + 160 190 200 180 +/* CG.CG..GU */ + 70 200 200 180 + 200 200 200 200 + 120 210 200 200 + DEF 80 200 70 +/* CG.CU..GU */ + 200 200 200 200 + 160 190 200 180 + 50 180 200 160 + 80 110 200 100 +/* CG.GA..GU */ + 100 200 180 180 + 80 200 150 60 + -20 200 50 140 + 200 200 200 200 +/* CG.GC..GU */ + 90 200 160 70 + 170 200 210 150 + 200 200 200 200 + 170 200 210 150 +/* CG.GG..GU */ + -20 200 50 140 + 200 200 200 200 + 30 200 110 110 + 40 200 40 -160 +/* CG.GU..GU */ + 200 200 200 200 + 170 200 210 150 + 140 200 130 -60 + 180 200 170 160 +/* CG.UA..GU */ + 200 270 30 220 + 200 180 -90 90 + 200 180 -10 180 + 200 200 200 200 +/* CG.UC..GU */ + 200 190 -80 100 + 200 180 0 90 + 200 200 200 200 + 200 180 0 90 +/* CG.UG..GU */ + 200 180 -10 180 + 200 200 200 200 + 200 200 -40 150 + 200 70 -310 60 +/* CG.UU..GU */ + 200 200 200 200 + 200 180 0 90 + 200 160 -210 160 + 200 100 0 10 +/* CG.AA..UG */ + 200 240 100 200 + 160 190 60 200 + 100 130 0 200 + 200 200 200 200 +/* CG.AC..UG */ + 200 240 100 200 + 260 240 200 200 + 200 200 200 200 + 260 240 200 200 +/* CG.AG..UG */ + 100 130 0 200 + 200 200 200 200 + 140 170 40 200 + 20 -40 0 200 +/* CG.AU..UG */ + 200 200 200 200 + 230 210 170 200 + 150 80 130 200 + 220 150 200 200 +/* CG.CA..UG */ + 190 280 200 270 + 150 180 200 160 + 90 220 200 200 + 200 200 200 200 +/* CG.CC..UG */ + 190 220 200 210 + 190 220 200 210 + 200 200 200 200 + 190 220 200 210 +/* CG.CG..UG */ + 90 220 200 200 + 200 200 200 200 + 130 220 200 200 + -90 40 200 30 +/* CG.CU..UG */ + 200 200 200 200 + 160 190 200 180 + 40 170 200 150 + 110 140 200 120 +/* CG.GA..UG */ + 100 200 180 180 + 60 200 130 40 + 0 200 70 160 + 200 200 200 200 +/* CG.GC..UG */ + 100 200 180 80 + 200 200 240 180 + 200 200 200 200 + 200 200 240 180 +/* CG.GG..UG */ + 0 200 70 160 + 200 200 200 200 + 40 200 110 120 + 0 200 0 -200 +/* CG.GU..UG */ + 200 200 200 200 + 170 200 210 150 + 130 200 120 -70 + 200 200 190 180 +/* CG.UA..UG */ + 200 270 30 220 + 200 160 -110 70 + 200 200 10 190 + 200 200 200 200 +/* CG.UC..UG */ + 200 210 -70 120 + 200 210 30 120 + 200 200 200 200 + 200 210 30 120 +/* CG.UG..UG */ + 200 200 10 190 + 200 200 200 200 + 200 200 -30 150 + 200 30 -350 20 +/* CG.UU..UG */ + 200 200 200 200 + 200 180 0 90 + 200 150 -220 150 + 200 120 30 30 +/* CG.AA..AU */ + 200 240 100 200 + 180 210 80 200 + 80 110 -20 200 + 200 200 200 200 +/* CG.AC..AU */ + 190 220 90 200 + 230 210 170 200 + 200 200 200 200 + 230 210 170 200 +/* CG.AG..AU */ + 80 110 -20 200 + 200 200 200 200 + 130 170 30 200 + 60 0 40 200 +/* CG.AU..AU */ + 200 200 200 200 + 230 210 170 200 + 160 90 140 200 + 190 130 180 200 +/* CG.CA..AU */ + 190 280 200 270 + 170 200 200 180 + 70 200 200 180 + 200 200 200 200 +/* CG.CC..AU */ + 180 210 200 190 + 160 190 200 180 + 200 200 200 200 + 160 190 200 180 +/* CG.CG..AU */ + 70 200 200 180 + 200 200 200 200 + 120 210 200 200 + DEF 80 200 70 +/* CG.CU..AU */ + 200 200 200 200 + 160 190 200 180 + 50 180 200 160 + 80 110 200 100 +/* CG.GA..AU */ + 100 200 180 180 + 80 200 150 60 + -20 200 50 140 + 200 200 200 200 +/* CG.GC..AU */ + 90 200 160 70 + 170 200 210 150 + 200 200 200 200 + 170 200 210 150 +/* CG.GG..AU */ + -20 200 50 140 + 200 200 200 200 + 30 200 110 110 + 40 200 40 -160 +/* CG.GU..AU */ + 200 200 200 200 + 170 200 210 150 + 140 200 130 -60 + 180 200 170 160 +/* CG.UA..AU */ + 200 270 30 220 + 200 180 -90 90 + 200 180 -10 180 + 200 200 200 200 +/* CG.UC..AU */ + 200 190 -80 100 + 200 180 0 90 + 200 200 200 200 + 200 180 0 90 +/* CG.UG..AU */ + 200 180 -10 180 + 200 200 200 200 + 200 200 -40 150 + 200 70 -310 60 +/* CG.UU..AU */ + 200 200 200 200 + 200 180 0 90 + 200 160 -210 160 + 200 100 0 10 +/* CG.AA..UA */ + 200 240 100 200 + 160 190 60 200 + 100 130 0 200 + 200 200 200 200 +/* CG.AC..UA */ + 200 240 100 200 + 260 240 200 200 + 200 200 200 200 + 260 240 200 200 +/* CG.AG..UA */ + 100 130 0 200 + 200 200 200 200 + 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CG.AC..UG */ + -1818 -1738 -1818 -1818 + -1508 -1428 -1508 -1508 + -1838 -1758 -1838 -1838 + -1468 -1388 -1468 -1468 +/* CG.AG..UG */ + -1988 -1908 -1988 -1988 + -1388 -1308 -1388 -1388 + -1948 -1868 -1948 -1948 + -1578 -1498 -1578 -1578 +/* CG.AU..UG */ + -1838 -1758 -1838 -1838 + -1508 -1428 -1508 -1508 + -1838 -1758 -1838 -1838 + -1388 -1308 -1388 -1388 +/* CG.CA..UG */ + -1238 -1168 -1238 -1388 + -998 -928 -998 -1148 + -1178 -1108 -1178 -1328 + -1068 -998 -1068 -1218 +/* CG.CC..UG */ + -1308 -1238 -1308 -1458 + -998 -928 -998 -1148 + -1328 -1258 -1328 -1478 + -958 -888 -958 -1108 +/* CG.CG..UG */ + -1478 -1408 -1478 -1628 + -878 -808 -878 -1028 + -1438 -1368 -1438 -1588 + -1068 -998 -1068 -1218 +/* CG.CU..UG */ + -1328 -1258 -1328 -1478 + -998 -928 -998 -1148 + -1328 -1258 -1328 -1478 + -878 -808 -878 -1028 +/* CG.GA..UG */ + -1658 -1658 -1658 -1658 + -1418 -1418 -1418 -1418 + -1598 -1598 -1598 -1598 + -1488 -1488 -1488 -1488 +/* CG.GC..UG */ + -1728 -1728 -1728 -1728 + -1418 -1418 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GC.AC..UA */ + -1148 -1508 -1188 -1508 + -1028 -1388 -1068 -1388 + -1198 -1558 -1238 -1558 + -658 -1018 -698 -1018 +/* GC.AG..UA */ + -1408 -1768 -1448 -1768 + -718 -1078 -758 -1078 + -1408 -1768 -1448 -1768 + -798 -1158 -838 -1158 +/* GC.AU..UA */ + -1108 -1468 -1148 -1468 + -698 -1058 -738 -1058 + -1198 -1558 -1238 -1558 + -659 -1019 -699 -1019 +/* GC.CA..UA */ + -1118 -708 -708 -788 + -1148 -738 -738 -818 + -1098 -688 -688 -768 + -998 -588 -588 -668 +/* GC.CC..UA */ + -1348 -938 -938 -1018 + -1228 -818 -818 -898 + -1398 -988 -988 -1068 + -858 -448 -448 -528 +/* GC.CG..UA */ + -1608 -1198 -1198 -1278 + -918 -508 -508 -588 + -1608 -1198 -1198 -1278 + -998 -588 -588 -668 +/* GC.CU..UA */ + -1308 -898 -898 -978 + -898 -488 -488 -568 + -1398 -988 -988 -1068 + -859 -449 -449 -529 +/* GC.GA..UA */ + -1108 -1138 -1018 -1138 + -1138 -1168 -1048 -1168 + -1088 -1118 -998 -1118 + -988 -1018 -898 -1018 +/* GC.GC..UA */ + -1338 -1368 -1248 -1368 + -1218 -1248 -1128 -1248 + -1388 -1418 -1298 -1418 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-1308 -1478 -1478 -1478 + -818 -988 -988 -988 + -1168 -1338 -1338 -1338 + -998 -1168 -1168 -1168 +/* AU.CA..GC */ + -778 -758 -758 -758 + -978 -958 -958 -958 + -968 -948 -948 -948 + -758 -738 -738 -738 +/* AU.CC..GC */ + -1138 -1118 -1118 -1118 + -568 -548 -548 -548 + -998 -978 -978 -978 + -758 -738 -738 -738 +/* AU.CG..GC */ + -818 -798 -798 -798 + -568 -548 -548 -548 + -878 -858 -858 -858 + -758 -738 -738 -738 +/* AU.CU..GC */ + -1138 -1118 -1118 -1118 + -648 -628 -628 -628 + -998 -978 -978 -978 + -828 -808 -808 -808 +/* AU.GA..GC */ + -858 -1208 -1208 -1208 + -1058 -1408 -1408 -1408 + -1048 -1398 -1398 -1398 + -838 -1188 -1188 -1188 +/* AU.GC..GC */ + -1218 -1568 -1568 -1568 + -648 -998 -998 -998 + -1078 -1428 -1428 -1428 + -838 -1188 -1188 -1188 +/* AU.GG..GC */ + -898 -1248 -1248 -1248 + -648 -998 -998 -998 + -958 -1308 -1308 -1308 + -838 -1188 -1188 -1188 +/* AU.GU..GC */ + -1218 -1568 -1568 -1568 + -728 -1078 -1078 -1078 + -1078 -1428 -1428 -1428 + -908 -1258 -1258 -1258 +/* AU.UA..GC */ + -848 -848 -848 -848 + -1048 -1048 -1048 -1048 + -1038 -1038 -1038 -1038 + -828 -828 -828 -828 +/* AU.UC..GC */ + -1208 -1208 -1208 -1208 + -638 -638 -638 -638 + -1068 -1068 -1068 -1068 + -828 -828 -828 -828 +/* AU.UG..GC */ + -888 -888 -888 -888 + -638 -638 -638 -638 + -948 -948 -948 -948 + -828 -828 -828 -828 +/* AU.UU..GC */ + -1208 -1208 -1208 -1208 + -718 -718 -718 -718 + -1068 -1068 -1068 -1068 + -898 -898 -898 -898 +/* AU.AA..GU */ + -858 -1028 -1028 -1028 + -688 -858 -858 -858 + -768 -938 -938 -938 + -758 -928 -928 -928 +/* AU.AC..GU */ + -1028 -1198 -1198 -1198 + -668 -838 -838 -838 + -1118 -1288 -1288 -1288 + -758 -928 -928 -928 +/* AU.AG..GU */ + -1028 -1198 -1198 -1198 + -668 -838 -838 -838 + -1118 -1288 -1288 -1288 + -758 -928 -928 -928 +/* AU.AU..GU */ + -1028 -1198 -1198 -1198 + -668 -838 -838 -838 + -1118 -1288 -1288 -1288 + -758 -928 -928 -928 +/* AU.CA..GU */ + -688 -668 -668 -668 + -518 -498 -498 -498 + -598 -578 -578 -578 + -588 -568 -568 -568 +/* AU.CC..GU */ + -858 -838 -838 -838 + -498 -478 -478 -478 + -948 -928 -928 -928 + -588 -568 -568 -568 +/* AU.CG..GU */ + -858 -838 -838 -838 + -498 -478 -478 -478 + -948 -928 -928 -928 + -588 -568 -568 -568 +/* AU.CU..GU */ + -858 -838 -838 -838 + -498 -478 -478 -478 + -948 -928 -928 -928 + -588 -568 -568 -568 +/* AU.GA..GU */ + -768 -1118 -1118 -1118 + -598 -948 -948 -948 + -678 -1028 -1028 -1028 + -668 -1018 -1018 -1018 +/* AU.GC..GU */ + -938 -1288 -1288 -1288 + -578 -928 -928 -928 + -1028 -1378 -1378 -1378 + -668 -1018 -1018 -1018 +/* AU.GG..GU */ + -938 -1288 -1288 -1288 + -578 -928 -928 -928 + -1028 -1378 -1378 -1378 + -668 -1018 -1018 -1018 +/* AU.GU..GU */ + -938 -1288 -1288 -1288 + -578 -928 -928 -928 + -1028 -1378 -1378 -1378 + -668 -1018 -1018 -1018 +/* AU.UA..GU */ + -758 -758 -758 -758 + -588 -588 -588 -588 + -668 -668 -668 -668 + -658 -658 -658 -658 +/* AU.UC..GU */ + -928 -928 -928 -928 + -568 -568 -568 -568 + -1018 -1018 -1018 -1018 + -658 -658 -658 -658 +/* AU.UG..GU */ 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-668 -1018 -1018 -1018 +/* AU.GC..AU */ + -938 -1288 -1288 -1288 + -578 -928 -928 -928 + -1028 -1378 -1378 -1378 + -668 -1018 -1018 -1018 +/* AU.GG..AU */ + -938 -1288 -1288 -1288 + -578 -928 -928 -928 + -1028 -1378 -1378 -1378 + -668 -1018 -1018 -1018 +/* AU.GU..AU */ + -938 -1288 -1288 -1288 + -578 -928 -928 -928 + -1028 -1378 -1378 -1378 + -668 -1018 -1018 -1018 +/* AU.UA..AU */ + -758 -758 -758 -758 + -588 -588 -588 -588 + -668 -668 -668 -668 + -658 -658 -658 -658 +/* AU.UC..AU */ + -928 -928 -928 -928 + -568 -568 -568 -568 + -1018 -1018 -1018 -1018 + -658 -658 -658 -658 +/* AU.UG..AU */ + -928 -928 -928 -928 + -568 -568 -568 -568 + -1018 -1018 -1018 -1018 + -658 -658 -658 -658 +/* AU.UU..AU */ + -928 -928 -928 -928 + -568 -568 -568 -568 + -1018 -1018 -1018 -1018 + -658 -658 -658 -658 +/* AU.AA..UA */ + -828 -998 -998 -998 + -858 -1028 -1028 -1028 + -808 -978 -978 -978 + -708 -878 -878 -878 +/* AU.AC..UA */ + -1058 -1228 -1228 -1228 + -938 -1108 -1108 -1108 + -1108 -1278 -1278 -1278 + -568 -738 -738 -738 +/* AU.AG..UA */ + -1318 -1488 -1488 -1488 + -628 -798 -798 -798 + -1318 -1488 -1488 -1488 + -708 -878 -878 -878 +/* AU.AU..UA */ + -1018 -1188 -1188 -1188 + -608 -778 -778 -778 + -1108 -1278 -1278 -1278 + -569 -739 -739 -739 +/* AU.CA..UA */ + -658 -638 -638 -638 + -688 -668 -668 -668 + -638 -618 -618 -618 + -538 -518 -518 -518 +/* AU.CC..UA */ + -888 -868 -868 -868 + -768 -748 -748 -748 + -938 -918 -918 -918 + -398 -378 -378 -378 +/* AU.CG..UA */ + -1148 -1128 -1128 -1128 + -458 -438 -438 -438 + -1148 -1128 -1128 -1128 + -538 -518 -518 -518 +/* AU.CU..UA */ + -848 -828 -828 -828 + -438 -418 -418 -418 + -938 -918 -918 -918 + -399 -379 -379 -379 +/* AU.GA..UA */ + -738 -1088 -1088 -1088 + -768 -1118 -1118 -1118 + -718 -1068 -1068 -1068 + -618 -968 -968 -968 +/* AU.GC..UA */ + -968 -1318 -1318 -1318 + -848 -1198 -1198 -1198 + -1018 -1368 -1368 -1368 + -478 -828 -828 -828 +/* AU.GG..UA */ + -1228 -1578 -1578 -1578 + -538 -888 -888 -888 + -1228 -1578 -1578 -1578 + -618 -968 -968 -968 +/* AU.GU..UA */ + -928 -1278 -1278 -1278 + -518 -868 -868 -868 + -1018 -1368 -1368 -1368 + -479 -829 -829 -829 +/* AU.UA..UA */ + -728 -728 -728 -728 + -758 -758 -758 -758 + -708 -708 -708 -708 + -608 -608 -608 -608 +/* AU.UC..UA */ + -958 -958 -958 -958 + -838 -838 -838 -838 + -1008 -1008 -1008 -1008 + -468 -468 -468 -468 +/* AU.UG..UA */ + -1218 -1218 -1218 -1218 + -528 -528 -528 -528 + -1218 -1218 -1218 -1218 + -608 -608 -608 -608 +/* AU.UU..UA */ + -918 -918 -918 -918 + -508 -508 -508 -508 + -1008 -1008 -1008 -1008 + -469 -469 -469 -469 +/* UA.AA..CG */ + -1428 -1658 -1918 -1618 + -918 -1148 -1408 -1108 + -1338 -1568 -1828 -1528 + -1208 -1438 -1698 -1398 +/* UA.AC..CG */ + -1348 -1578 -1838 -1538 + -848 -1078 -1338 -1038 + -1338 -1568 -1828 -1528 + -1138 -1368 -1628 -1328 +/* UA.AG..CG */ + -1428 -1658 -1918 -1618 + -918 -1148 -1408 -1108 + -1338 -1568 -1828 -1528 + -1208 -1438 -1698 -1398 +/* UA.AU..CG */ + -1428 -1658 -1918 -1618 + -1068 -1298 -1558 -1258 + -1338 -1568 -1828 -1528 + -1258 -1488 -1748 -1448 +/* UA.CA..CG */ + -1458 -1538 -1228 -1208 + -948 -1028 -718 -698 + -1368 -1448 -1138 -1118 + -1238 -1318 -1008 -988 +/* UA.CC..CG */ + -1378 -1458 -1148 -1128 + -878 -958 -648 -628 + -1368 -1448 -1138 -1118 + -1168 -1248 -938 -918 +/* UA.CG..CG */ + -1458 -1538 -1228 -1208 + -948 -1028 -718 -698 + -1368 -1448 -1138 -1118 + -1238 -1318 -1008 -988 +/* UA.CU..CG */ + -1458 -1538 -1228 -1208 + -1098 -1178 -868 -848 + -1368 -1448 -1138 -1118 + -1288 -1368 -1058 -1038 +/* UA.GA..CG */ + -1408 -1708 -1918 -1708 + -898 -1198 -1408 -1198 + -1318 -1618 -1828 -1618 + -1188 -1488 -1698 -1488 +/* UA.GC..CG */ + -1328 -1628 -1838 -1628 + -828 -1128 -1338 -1128 + -1318 -1618 -1828 -1618 + -1118 -1418 -1628 -1418 +/* UA.GG..CG */ + -1408 -1708 -1918 -1708 + -898 -1198 -1408 -1198 + -1318 -1618 -1828 -1618 + -1188 -1488 -1698 -1488 +/* UA.GU..CG */ + -1408 -1708 -1918 -1708 + -1048 -1348 -1558 -1348 + -1318 -1618 -1828 -1618 + -1238 -1538 -1748 -1538 +/* UA.UA..CG */ + -1308 -1168 -1308 -1169 + -798 -658 -798 -659 + -1218 -1078 -1218 -1079 + -1088 -948 -1088 -949 +/* UA.UC..CG */ + -1228 -1088 -1228 -1089 + -728 -588 -728 -589 + -1218 -1078 -1218 -1079 + -1018 -878 -1018 -879 +/* UA.UG..CG */ + -1308 -1168 -1308 -1169 + -798 -658 -798 -659 + -1218 -1078 -1218 -1079 + -1088 -948 -1088 -949 +/* UA.UU..CG */ + -1308 -1168 -1308 -1169 + -948 -808 -948 -809 + -1218 -1078 -1218 -1079 + -1138 -998 -1138 -999 +/* UA.AA..GC */ + -918 -1148 -1408 -1108 + -1118 -1348 -1608 -1308 + -1108 -1338 -1598 -1298 + -898 -1128 -1388 -1088 +/* UA.AC..GC */ + -1278 -1508 -1768 -1468 + -708 -938 -1198 -898 + -1138 -1368 -1628 -1328 + -898 -1128 -1388 -1088 +/* UA.AG..GC */ + -958 -1188 -1448 -1148 + -708 -938 -1198 -898 + -1018 -1248 -1508 -1208 + -898 -1128 -1388 -1088 +/* UA.AU..GC */ + -1278 -1508 -1768 -1468 + -788 -1018 -1278 -978 + -1138 -1368 -1628 -1328 + -968 -1198 -1458 -1158 +/* UA.CA..GC */ + -948 -1028 -718 -698 + -1148 -1228 -918 -898 + -1138 -1218 -908 -888 + -928 -1008 -698 -678 +/* UA.CC..GC */ + -1308 -1388 -1078 -1058 + -738 -818 -508 -488 + -1168 -1248 -938 -918 + -928 -1008 -698 -678 +/* UA.CG..GC */ + -988 -1068 -758 -738 + -738 -818 -508 -488 + -1048 -1128 -818 -798 + -928 -1008 -698 -678 +/* UA.CU..GC */ + -1308 -1388 -1078 -1058 + -818 -898 -588 -568 + -1168 -1248 -938 -918 + -998 -1078 -768 -748 +/* UA.GA..GC */ + -898 -1198 -1408 -1198 + -1098 -1398 -1608 -1398 + -1088 -1388 -1598 -1388 + -878 -1178 -1388 -1178 +/* UA.GC..GC */ + -1258 -1558 -1768 -1558 + -688 -988 -1198 -988 + -1118 -1418 -1628 -1418 + -878 -1178 -1388 -1178 +/* UA.GG..GC */ + -938 -1238 -1448 -1238 + -688 -988 -1198 -988 + -998 -1298 -1508 -1298 + -878 -1178 -1388 -1178 +/* UA.GU..GC */ + -1258 -1558 -1768 -1558 + -768 -1068 -1278 -1068 + -1118 -1418 -1628 -1418 + -948 -1248 -1458 -1248 +/* UA.UA..GC */ + -798 -658 -798 -659 + -998 -858 -998 -859 + -988 -848 -988 -849 + -778 -638 -778 -639 +/* UA.UC..GC */ + -1158 -1018 -1158 -1019 + -588 -448 -588 -449 + -1018 -878 -1018 -879 + -778 -638 -778 -639 +/* UA.UG..GC */ + -838 -698 -838 -699 + -588 -448 -588 -449 + -898 -758 -898 -759 + -778 -638 -778 -639 +/* UA.UU..GC */ + -1158 -1018 -1158 -1019 + -668 -528 -668 -529 + -1018 -878 -1018 -879 + -848 -708 -848 -709 +/* UA.AA..GU */ + -828 -1058 -1318 -1018 + -658 -888 -1148 -848 + -738 -968 -1228 -928 + -728 -958 -1218 -918 +/* UA.AC..GU */ + -998 -1228 -1488 -1188 + -638 -868 -1128 -828 + -1088 -1318 -1578 -1278 + -728 -958 -1218 -918 +/* UA.AG..GU */ + -998 -1228 -1488 -1188 + -638 -868 -1128 -828 + -1088 -1318 -1578 -1278 + -728 -958 -1218 -918 +/* UA.AU..GU */ + -998 -1228 -1488 -1188 + -638 -868 -1128 -828 + -1088 -1318 -1578 -1278 + -728 -958 -1218 -918 +/* UA.CA..GU */ + -858 -938 -628 -608 + -688 -768 -458 -438 + -768 -848 -538 -518 + -758 -838 -528 -508 +/* UA.CC..GU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.CG..GU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.CU..GU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.GA..GU */ + -808 -1108 -1318 -1108 + -638 -938 -1148 -938 + -718 -1018 -1228 -1018 + -708 -1008 -1218 -1008 +/* UA.GC..GU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.GG..GU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.GU..GU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.UA..GU */ + -708 -568 -708 -569 + -538 -398 -538 -399 + -618 -478 -618 -479 + -608 -468 -608 -469 +/* UA.UC..GU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.UG..GU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.UU..GU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.AA..UG */ + -1118 -1348 -1608 -1308 + -878 -1108 -1368 -1068 + -1058 -1288 -1548 -1248 + -948 -1178 -1438 -1138 +/* UA.AC..UG */ + -1188 -1418 -1678 -1378 + -878 -1108 -1368 -1068 + -1208 -1438 -1698 -1398 + -838 -1068 -1328 -1028 +/* UA.AG..UG */ + -1358 -1588 -1848 -1548 + -758 -988 -1248 -948 + -1318 -1548 -1808 -1508 + -948 -1178 -1438 -1138 +/* UA.AU..UG */ + -1208 -1438 -1698 -1398 + -878 -1108 -1368 -1068 + -1208 -1438 -1698 -1398 + -758 -988 -1248 -948 +/* UA.CA..UG */ + -1148 -1228 -918 -898 + -908 -988 -678 -658 + -1088 -1168 -858 -838 + -978 -1058 -748 -728 +/* UA.CC..UG */ + -1218 -1298 -988 -968 + -908 -988 -678 -658 + -1238 -1318 -1008 -988 + -868 -948 -638 -618 +/* UA.CG..UG */ + -1388 -1468 -1158 -1138 + -788 -868 -558 -538 + -1348 -1428 -1118 -1098 + -978 -1058 -748 -728 +/* UA.CU..UG */ + -1238 -1318 -1008 -988 + -908 -988 -678 -658 + -1238 -1318 -1008 -988 + -788 -868 -558 -538 +/* UA.GA..UG */ + -1098 -1398 -1608 -1398 + -858 -1158 -1368 -1158 + -1038 -1338 -1548 -1338 + -928 -1228 -1438 -1228 +/* UA.GC..UG */ + -1168 -1468 -1678 -1468 + -858 -1158 -1368 -1158 + -1188 -1488 -1698 -1488 + -818 -1118 -1328 -1118 +/* UA.GG..UG */ + -1338 -1638 -1848 -1638 + -738 -1038 -1248 -1038 + -1298 -1598 -1808 -1598 + -928 -1228 -1438 -1228 +/* UA.GU..UG */ + -1188 -1488 -1698 -1488 + -858 -1158 -1368 -1158 + -1188 -1488 -1698 -1488 + -738 -1038 -1248 -1038 +/* UA.UA..UG */ + -998 -858 -998 -859 + -758 -618 -758 -619 + -938 -798 -938 -799 + -828 -688 -828 -689 +/* UA.UC..UG */ + -1068 -928 -1068 -929 + -758 -618 -758 -619 + -1088 -948 -1088 -949 + -718 -578 -718 -579 +/* UA.UG..UG */ + -1238 -1098 -1238 -1099 + -638 -498 -638 -499 + -1198 -1058 -1198 -1059 + -828 -688 -828 -689 +/* UA.UU..UG */ + -1088 -948 -1088 -949 + -758 -618 -758 -619 + -1088 -948 -1088 -949 + -638 -498 -638 -499 +/* UA.AA..AU */ + -828 -1058 -1318 -1018 + -658 -888 -1148 -848 + -738 -968 -1228 -928 + -728 -958 -1218 -918 +/* UA.AC..AU */ + -998 -1228 -1488 -1188 + -638 -868 -1128 -828 + -1088 -1318 -1578 -1278 + -728 -958 -1218 -918 +/* UA.AG..AU */ + -998 -1228 -1488 -1188 + -638 -868 -1128 -828 + -1088 -1318 -1578 -1278 + -728 -958 -1218 -918 +/* UA.AU..AU */ + -998 -1228 -1488 -1188 + -638 -868 -1128 -828 + -1088 -1318 -1578 -1278 + -728 -958 -1218 -918 +/* UA.CA..AU */ + -858 -938 -628 -608 + -688 -768 -458 -438 + -768 -848 -538 -518 + -758 -838 -528 -508 +/* UA.CC..AU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.CG..AU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.CU..AU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.GA..AU */ + -808 -1108 -1318 -1108 + -638 -938 -1148 -938 + -718 -1018 -1228 -1018 + -708 -1008 -1218 -1008 +/* UA.GC..AU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.GG..AU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.GU..AU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.UA..AU */ + -708 -568 -708 -569 + -538 -398 -538 -399 + -618 -478 -618 -479 + -608 -468 -608 -469 +/* UA.UC..AU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.UG..AU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.UU..AU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.AA..UA */ + -798 -1028 -1288 -988 + -828 -1058 -1318 -1018 + -778 -1008 -1268 -968 + -678 -908 -1168 -868 +/* UA.AC..UA */ + -1028 -1258 -1518 -1218 + -908 -1138 -1398 -1098 + -1078 -1308 -1568 -1268 + -538 -768 -1028 -728 +/* UA.AG..UA */ + -1288 -1518 -1778 -1478 + -598 -828 -1088 -788 + -1288 -1518 -1778 -1478 + -678 -908 -1168 -868 +/* UA.AU..UA */ + -988 -1218 -1478 -1178 + -578 -808 -1068 -768 + -1078 -1308 -1568 -1268 + -539 -769 -1029 -729 +/* UA.CA..UA */ + -828 -908 -598 -578 + -858 -938 -628 -608 + -808 -888 -578 -558 + -708 -788 -478 -458 +/* UA.CC..UA */ + -1058 -1138 -828 -808 + -938 -1018 -708 -688 + -1108 -1188 -878 -858 + -568 -648 -338 -318 +/* UA.CG..UA */ + -1318 -1398 -1088 -1068 + -628 -708 -398 -378 + -1318 -1398 -1088 -1068 + -708 -788 -478 -458 +/* UA.CU..UA */ + -1018 -1098 -788 -768 + -608 -688 -378 -358 + -1108 -1188 -878 -858 + -569 -649 -339 -319 +/* UA.GA..UA */ + -778 -1078 -1288 -1078 + -808 -1108 -1318 -1108 + -758 -1058 -1268 -1058 + -658 -958 -1168 -958 +/* UA.GC..UA */ + -1008 -1308 -1518 -1308 + -888 -1188 -1398 -1188 + -1058 -1358 -1568 -1358 + -518 -818 -1028 -818 +/* UA.GG..UA */ + -1268 -1568 -1778 -1568 + -578 -878 -1088 -878 + -1268 -1568 -1778 -1568 + -658 -958 -1168 -958 +/* UA.GU..UA */ + -968 -1268 -1478 -1268 + -558 -858 -1068 -858 + -1058 -1358 -1568 -1358 + -519 -819 -1029 -819 +/* UA.UA..UA */ + -678 -538 -678 -539 + -708 -568 -708 -569 + -658 -518 -658 -519 + -558 -418 -558 -419 +/* UA.UC..UA */ + -908 -768 -908 -769 + -788 -648 -788 -649 + -958 -818 -958 -819 + -418 -278 -418 -279 +/* UA.UG..UA */ + -1168 -1028 -1168 -1029 + -478 -338 -478 -339 + -1168 -1028 -1168 -1029 + -558 -418 -558 -419 +/* UA.UU..UA */ + -868 -728 -868 -729 + -458 -318 -458 -319 + -958 -818 -958 -819 + -419 -279 -419 -280 + +# hairpin + INF INF INF 570 560 560 540 590 560 640 + 650 660 670 678 686 694 701 707 713 719 + 725 730 735 740 744 749 753 757 761 765 + 769 + +# hairpin_enthalpies + INF INF INF 0 0 0 0 0 0 0 + 0 0 0 0 0 0 0 0 0 0 + 0 0 0 0 0 0 0 0 0 0 + 0 + +# bulge + INF 380 280 320 360 400 440 459 470 480 + 490 500 510 519 527 534 541 548 554 560 + 565 571 576 580 585 589 594 598 602 605 + 609 + +# bulge_enthalpies + INF 0 0 0 0 0 0 0 0 0 + 0 0 0 0 0 0 0 0 0 0 + 0 0 0 0 0 0 0 0 0 0 + 0 + +# interior + INF INF 410 510 170 180 200 220 230 240 + 250 260 270 278 286 294 301 307 313 319 + 325 330 335 340 345 349 353 357 361 365 + 369 + +# interior_enthalpies + INF INF INF INF 0 0 0 0 0 0 + 0 0 0 0 0 0 0 0 0 0 + 0 0 0 0 0 0 0 0 0 0 + 0 + +# NINIO +/* Ninio = MIN(max, m*|n1-n2| */ +/* m m_dH max */ + 50 0 300 + +# ML_params +/* F = cu*n_unpaired + cc + ci*loop_degree (+TermAU) */ +/* cu cu_dH cc cc_dH ci ci_dH */ + 0 0 340 0 40 0 + +# Misc +/* all parameters are pairs of 'energy enthalpy' */ +/* DuplexInit TerminalAU LXC */ + 410 0 50 0 107.856000 0 + +# Triloops + +# Tetraloops + GGGGAC 20 -1110 + GGUGAC 20 -1110 + CGAAAG 40 -1340 + GGAGAC 20 -1110 + CGCAAG 40 -1340 + GGAAAC 20 -1110 + CGGAAG 40 -1340 + CUUCGG 80 -1210 + CGUGAG 40 -1340 + CGAAGG 150 -1340 + CUACGG 130 -1210 + GGCAAC 70 -1110 + CGCGAG 90 -1340 + UGAGAG 230 -1060 + CGAGAG 140 -1340 + AGAAAU 250 -740 + CGUAAG 140 -1340 + CUAACG 220 -1140 + UGAAAG 280 -1060 + GGAAGC 270 -1020 + GGGAAC 170 -1110 + UGAAAA 270 -780 + AGCAAU 300 -740 + AGUAAU 300 -740 + CGGGAG 190 -1340 + AGUGAU 300 -740 + GGCGAC 170 -1110 + GGGAGC 270 -1020 + GUGAAC 220 -900 + UGGAAA 270 -780 + +# Hexaloops + + +# END