Mercurial > repos > testtool > geo_data
diff getGEO/getGEO.R @ 10:cbc8174bd361 draft
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author | testtool |
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date | Mon, 20 Mar 2017 06:54:27 -0400 |
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children | fc93085430a8 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/getGEO/getGEO.R Mon Mar 20 06:54:27 2017 -0400 @@ -0,0 +1,54 @@ +require("BiocGenerics", quietly = TRUE) +require("data.table", quietly = TRUE) +require("GEOquery", quietly = TRUE) +require("rtracklayer", quietly = TRUE) +require("FDb.InfiniumMethylation.hg19", quietly = TRUE) + +options("download.file.method.GEOquery"="wget") +options(warn = -1) + +args <- commandArgs(trailingOnly = TRUE) +GSMTable = args[1] +protocol = args[2] +platform = args[3] +Data_Table = args[4] + +TAB = fread(GSMTable) + +if (is.null(TAB)) { + stop("Must specify input files") +} else { + GEODataTable <- getGEO(TAB$ID[1], getGPL = FALSE) + IlmnIDTable <- Table(GEODataTable) + MetaData <- data.frame(Meta(GEODataTable)) + + + write.table(MetaData, protocol, row.names = FALSE, sep = "\t") +} + +hm450.hg19 <- getPlatform() + +IlmnInfo <- + data.table( + IlmnID = names(hm450.hg19), + CHR = as.data.frame(hm450.hg19@seqnames)$value, + BP = as.numeric(hm450.hg19@elementMetadata$probeStart) + ) + + +write.table(IlmnInfo, platform, row.names = FALSE, sep = "\t") + + +if (length(TAB$ID) > 1) { + mysamples <- + do.call("data.table", lapply(TAB$ID[-1], function(x) + Table(getGEO(x, getGPL = FALSE))[, -1])) + + gmSet <- data.table(IlmnIDTable[, -1], mysamples) + +} else { + gmSet <- Table(getGEO(TAB$ID, getGPL = FALSE)) +} + +write.table(gmSet, Data_Table, row.names = FALSE,quote=FALSE,sep="\t") +