diff models/README.md @ 0:6e75a84e9338 draft

planemo upload commit e96b43f96afce6a7b7dfd4499933aad7d05c955e-dirty
author thondeboer
date Tue, 15 May 2018 02:39:53 -0400
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+# models
+Used by genReads.py for simulating various characteristics of NGS datasets.
+
+
+## mutation models
+
+* Used via '-m' parameter
+
+**MutModel_NA12878.p** - Mimic mutations via statistics derived from NA12878 germline variant calls.
+(Note that due to filesize restrictions, this one will need to be unzipped first)
+**MutModel_BRCA_US_ICGC.p** - Aggregate breast cancer mutation statistics from deidentified ICGC data.
+**MutModel_CLLE-ES_ICGC.p** - Aggregate leukemia mutation statistics from deidentified ICGC data.
+**MutModel_SKCM-US_ICGC.p** - Aggregate melanoma mutation statistics from deidentified ICGC data.
+
+
+## sequencing error models
+
+* Used via '-e' parameter
+
+**errorModel_toy.p** - Sequencing error statistics derived from in-house NGS data.
+
+
+## paired-end fragment length distribution model
+
+* Used via '--pe-model' parameter
+
+**fraglenModel_toy.p** - Fragment length statistics derived from in-house NGS data.
+
+
+## GC% coverage bias model
+
+* Used via '--gc-model' parameter
+
+**gcBias_toy.p** - GC% coverage bias statistics derived from in-house NGS data.