Mercurial > repos > thondeboer > neat_genreads
diff models/README.md @ 0:6e75a84e9338 draft
planemo upload commit e96b43f96afce6a7b7dfd4499933aad7d05c955e-dirty
| author | thondeboer |
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| date | Tue, 15 May 2018 02:39:53 -0400 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/models/README.md Tue May 15 02:39:53 2018 -0400 @@ -0,0 +1,34 @@ +# models +Used by genReads.py for simulating various characteristics of NGS datasets. + + +## mutation models + +* Used via '-m' parameter + +**MutModel_NA12878.p** - Mimic mutations via statistics derived from NA12878 germline variant calls. +(Note that due to filesize restrictions, this one will need to be unzipped first) +**MutModel_BRCA_US_ICGC.p** - Aggregate breast cancer mutation statistics from deidentified ICGC data. +**MutModel_CLLE-ES_ICGC.p** - Aggregate leukemia mutation statistics from deidentified ICGC data. +**MutModel_SKCM-US_ICGC.p** - Aggregate melanoma mutation statistics from deidentified ICGC data. + + +## sequencing error models + +* Used via '-e' parameter + +**errorModel_toy.p** - Sequencing error statistics derived from in-house NGS data. + + +## paired-end fragment length distribution model + +* Used via '--pe-model' parameter + +**fraglenModel_toy.p** - Fragment length statistics derived from in-house NGS data. + + +## GC% coverage bias model + +* Used via '--gc-model' parameter + +**gcBias_toy.p** - GC% coverage bias statistics derived from in-house NGS data.
