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view java-genomics-toolkit/src/edu/unc/genomics/nucleosomes/Phasogram.java @ 0:1daf3026d231
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author | timpalpant |
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date | Mon, 13 Feb 2012 21:55:55 -0500 |
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package edu.unc.genomics.nucleosomes; import java.io.BufferedWriter; import java.io.IOException; import java.nio.charset.Charset; import java.nio.file.Files; import java.nio.file.Path; import org.apache.log4j.Logger; import com.beust.jcommander.Parameter; import edu.unc.genomics.CommandLineTool; import edu.unc.genomics.CommandLineToolException; import edu.unc.genomics.io.WigFile; import edu.unc.genomics.io.WigFileException; public class Phasogram extends CommandLineTool { private static final Logger log = Logger.getLogger(Phasogram.class); @Parameter(names = {"-i", "--input"}, description = "Input wig file (read counts)", required = true) public WigFile inputFile; @Parameter(names = {"-m", "--max"}, description = "Maximum phase shift", required = true) public int maxPhase; @Parameter(names = {"-o", "--output"}, description = "Output file (histogram)", required = true) public Path outputFile; public void run() throws IOException { long[] phaseCounts = new long[maxPhase+1]; // Process each chromosome in the assembly for (String chr : inputFile.chromosomes()) { log.debug("Processing chromosome " + chr); int start = inputFile.getChrStart(chr); while (start < inputFile.getChrStop(chr)) { int stop = start + DEFAULT_CHUNK_SIZE - 1; try { float[] data = WigFile.flattenData(inputFile.query(chr, start, stop), start, stop); for (int i = 0; i < data.length-maxPhase; i++) { for (int j = 0; j <= maxPhase; j++) { phaseCounts[j] += data[i]; } } } catch (WigFileException e) { log.fatal("Error querying data from Wig file!"); e.printStackTrace(); throw new CommandLineToolException("Error querying data from Wig file!"); } // Process the next chunk start = stop - maxPhase + 1; } } log.debug("Writing output to disk"); try (BufferedWriter writer = Files.newBufferedWriter(outputFile, Charset.defaultCharset())) { for (int i = 0; i < phaseCounts.length; i++) { writer.write(i+"\t"+phaseCounts[i]); writer.newLine(); } } } public static void main(String[] args) { new Phasogram().instanceMain(args); } }