# HG changeset patch # User trinity_ctat # Date 1531842678 14400 # Node ID 1a7ec343001c98bebddb12e91f18961a5d7b693a Upload ctat tools. diff -r 000000000000 -r 1a7ec343001c ctat_fusion_inspector.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/ctat_fusion_inspector.xml Tue Jul 17 11:51:18 2018 -0400 @@ -0,0 +1,181 @@ + + In silico Validation of Fusion Transcript Predictions + + fusion-inspector + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + trinity_status['trinity'] == "true" + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +.. class:: infomark + +FusionInspector is a component of the Trinity Cancer Transcriptome Analysis Toolkit (CTAT). FusionInspector assists in fusion transcript discovery by performing a supervised analysis of fusion predictions, attempting to recover and re-score evidence for such predictions. Please read more here_. + +.. _here: https://github.com/FusionInspector/FusionInspector/wiki + +**To Visualize Output** + +After completion, results can be visualized in galaxy. Click on the output json file name in the history (on the right). A more detailed view of that file will be shown. Click on the button in the middle that looks like a bar chart. The visualization should now open for you to explore results. + +**There are several output files for the CTAT Fusion Inspector Pipeline. Files of interest include:** + +1. **fidx**: Finspector_fasta index file (required for visualization). + +2. **cytoBand**: Cytogenetic information for hg19. + +3. **finspector_fasta**: The candidate fusion-gene contigs. + +4. **finspector_bed**: The reference gene structure annotations for fusion partners. + +5. **FusionJuncSpan**: Tabular details on junction reads and spanning reads. + +6. **junction_bed**: Alignments of the breakpoint-junction supporting reads. + +7. **junction_bam**: Alignments of the breakpoint-junction supporting reads. + +8. **spanning_bam**: Alignments of the breakpoint-spanning paired-end reads. + +9. **spanning_bed**: Alignments of the breakpoint-spanning paired-end reads. + +10. **trinity_bed**: Fusion-guided Trinity assembly. + +11. **fusion_predictions.final**: All fusion evidence described. + +12. **fusion_predictions_abridged**: encompasses all information in fusion_predictions.final excluding the names of the reads. + +13. **fusion_json**: A logistical file that enables the visualization. + + + + + diff -r 000000000000 -r 1a7ec343001c test-data/FusionInspector/fusion_targets.A.txt --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/FusionInspector/fusion_targets.A.txt Tue Jul 17 11:51:18 2018 -0400 @@ -0,0 +1,24 @@ +ACACA--STAC2 +AHCTF1--NAAA +CTD-2328D6.1--MT-CO1 +DIDO1--TTI1 +FITM2--UQCC1 +GLB1--CMTM7 +LAMP1--MCF2L +MED1--ACSF2 +MED1--STXBP4 +MT-ND5--MT-RNR2 +PIP4K2B--RAD51C +RAB22A--MYO9B +RP11-96H19.1--RP11-446N19.1 +RPS6KB1--SNF8 +STARD3--DOK5 +STX16--RAE1 +STX16-NPEPL1--RAE1 +THRA--AC090627.1 +TOB1--SYNRG +TRIM37--MYO19 +TRPC4AP--MRPL45 +TULP4--RP11-732M18.3 +VAPB--IKZF3 +ZMYND8--CEP250 diff -r 000000000000 -r 1a7ec343001c test-data/FusionInspector/fusion_targets.B.txt --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/FusionInspector/fusion_targets.B.txt Tue Jul 17 11:51:18 2018 -0400 @@ -0,0 +1,22 @@ +ACACA--STAC2 +AHCTF1--NAAA +ASTN2--RP11-281A20.1 +CPNE1--PI3 +CTD-2319I12.2--HEATR6 +CTD-2328D6.1--MT-CO1 +DIDO1--TTI1 +FITM2--UQCC1 +GLB1--CMTM7 +RAB22A--MYO9B +RP11-96H19.1--RP11-446N19.1 +RPS6KB1--SNF8 +STARD3--DOK5 +STX16--RAE1 +STX16-NPEPL1--RAE1 +THRA--AC090627.1 +TOB1--SYNRG +TRIM37--MYO19 +TRPC4AP--MRPL45 +TULP4--RP11-732M18.3 +VAPB--IKZF3 +ZMYND8--CEP250 diff -r 000000000000 -r 1a7ec343001c test-data/FusionInspector/fusion_targets.C.txt --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/FusionInspector/fusion_targets.C.txt Tue Jul 17 11:51:18 2018 -0400 @@ -0,0 +1,24 @@ +ACACA--STAC2 +AHCTF1--NAAA +ASTN2--RP11-281A20.1 +CPNE1--PI3 +CTD-2319I12.2--HEATR6 +CTD-2328D6.1--MT-CO1 +DIDO1--TTI1 +FITM2--UQCC1 +GLB1--CMTM7 +LAMP1--MCF2L +MED1--ACSF2 +MED1--STXBP4 +MT-ND5--MT-RNR2 +PIP4K2B--RAD51C +RAB22A--MYO9B +RP11-96H19.1--RP11-446N19.1 +RPS6KB1--SNF8 +STARD3--DOK5 +STX16--RAE1 +STX16-NPEPL1--RAE1 +THRA--AC090627.1 +TOB1--SYNRG +TRIM37--MYO19 +ZMYND8--CEP250 diff -r 000000000000 -r 1a7ec343001c test-data/FusionInspector/test.reads_1.fastq.gz Binary file test-data/FusionInspector/test.reads_1.fastq.gz has changed diff -r 000000000000 -r 1a7ec343001c test-data/FusionInspector/test.reads_2.fastq.gz Binary file test-data/FusionInspector/test.reads_2.fastq.gz has changed diff -r 000000000000 -r 1a7ec343001c tool-data/ctat_genome_resource_libs.loc.sample --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool-data/ctat_genome_resource_libs.loc.sample Tue Jul 17 11:51:18 2018 -0400 @@ -0,0 +1,15 @@ +# This file lists the locations of CTAT Genome Resource Libraries +# Usually there will only be one library, but it is concievable +# that there could be multiple libraries. +# This file format is as follows +# (white space characters are TAB characters): +# +# +# value is a unique id +# name is the display name +# path is the directory where the genome resource lib files are stored +# +#ctat_genome_resource_libs.loc could look like: +# +#GRCh38_v27_CTAT_lib_Feb092018 CTAT_GenomeResourceLib_GRCh38_v27_CTAT_lib_Feb092018 /path/to/ctat/genome/resource/lib/directory +# diff -r 000000000000 -r 1a7ec343001c tool_data_table_conf.xml.sample --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool_data_table_conf.xml.sample Tue Jul 17 11:51:18 2018 -0400 @@ -0,0 +1,14 @@ + + + value, name, path + +
+ + value, name, path + +
+ + value, name, path + +
+