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view orthologs/hmmbuild.py @ 0:5b9a38ec4a39 draft default tip
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author | osiris_phylogenetics <ucsb_phylogenetics@lifesci.ucsb.edu> |
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date | Tue, 11 Mar 2014 12:19:13 -0700 |
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import os import optparse import subprocess from multiprocessing import Pool directory = "./data" results = "results.data" extension = ".afa" model_extension = ".hmm" inputFile = "" index_of_name_in_hmm = 6 def unescape(string): mapped_chars = { '>': '__gt__', '<': '__lt__', "'": '__sq__', '"': '__dq__', '[': '__ob__', ']': '__cb__', '{': '__oc__', '}': '__cc__', '@': '__at__', '\n': '__cn__', '\r': '__cr__', '\t': '__tc__', '#': '__pd__' } for key, value in mapped_chars.iteritems(): string = string.replace(value, key) return string def toData(text): lis = text.split() name = lis[index_of_name_in_hmm] text = name + "\t" + text.replace("\n", "\\n") return text def hmmbuild(input): file_name = directory + os.sep + input # print file_name # return subprocess.Popen(['hmmbuild', "--informat", "afa", file_name + ".hmm", file_name], stdout=subprocess.PIPE).communicate()[0] # ./muscle pop = subprocess.Popen(['hmmbuild', "--informat", "afa", file_name + ".hmm", file_name]) pop.wait() class Sequence: def __init__(self, string): lis = string.split('\t') # print lis self.species = lis[0] self.family = lis[1] self.name = lis[2] self.header = ' '.join(lis[:-1]) self.sequence = lis[-1] self.string = string def printFASTA(self): return '> ' + self.header + '\n' + self.sequence + '\n' def main(): usage = """%prog [options] options (listed below) default to 'None' if omitted """ parser = optparse.OptionParser(usage=usage) parser.add_option( '-i', '--in', dest='input', action='store', type='string', metavar="FILE", help='Name of input data.') options, args = parser.parse_args() global inputFile, directory inputFile = unescape(options.input) os.mkdir(directory) with open(inputFile) as f: for line in f: seq = Sequence(line) with open(directory + os.sep + seq.family + extension, "a") as p: p.write(seq.printFASTA()) pool = Pool() list_of_files = [file for file in os.listdir(directory) if file.lower().endswith(extension)] pool.map(hmmbuild, list_of_files) result = [file for file in os.listdir(directory) if file.lower().endswith(model_extension)] with open(directory + os.sep + results, "a") as f: for file in result: with open(directory + os.sep + file, "r") as r: f.write(toData(r.read()) + "\n") if __name__ == '__main__': main()