Mercurial > repos > vipints > rdiff
view rDiff/src/tools/detect_overlapping_regions.m @ 0:0f80a5141704
version 0.3 uploaded
author | vipints |
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date | Thu, 14 Feb 2013 23:38:36 -0500 |
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function [new_genes]=detect_overlapping_regions(genes); % this function determines regions in a gene which overlapp with % other genes. Those regons are then saved in the field "non_unique_regions" CHROMOSOMES={}; COUNTER=1; for i=1:size(genes,2) CHROMOSOMES{COUNTER}=genes(i).chr; COUNTER=COUNTER+1; end CHROMOSOMES=unique(CHROMOSOMES); INFO=zeros(size(genes,2),4); for i=1:size(genes,2) CHR_VAL=0; for chr= 1:length(CHROMOSOMES) if strcmp(genes(i).chr,CHROMOSOMES(chr)) CHR_VAL=chr; end end INFO(i,:)=[i,genes(i).start,genes(i).stop, CHR_VAL]; end COUNTER=1; new_genes=genes; for chr= 1:length(CHROMOSOMES) GENES_ON_CHR=INFO(INFO(:,4)==chr,:); [TEMP,POS]=sort(GENES_ON_CHR(:,2)); GENES_ON_CHR=GENES_ON_CHR(POS,:); STARTS=GENES_ON_CHR(:,2); STOPS=GENES_ON_CHR(:,3); for i=1:(size(GENES_ON_CHR,1)) MIN_START=find(STOPS>=STARTS(i),1,'first'); MAX_STOP=find(STARTS<=STOPS(i),1,'last'); if MIN_START==i MIN_START=[]; end if MAX_STOP==i MAX_STOP=[]; end EXONS=[]; if not (isempty(MIN_START)) for CURR=MIN_START:(i-1) if(not(isempty(genes(GENES_ON_CHR(CURR,1)).transcripts))) for tra=1:size(genes(GENES_ON_CHR(CURR,1)).transcripts,2) if(not(isempty(genes(GENES_ON_CHR(CURR,1)).exons))) EXONS=[EXONS;genes(GENES_ON_CHR(CURR,1)).exons{tra}]; else EXONS=[EXONS;genes(GENES_ON_CHR(CURR,1)).start,genes(GENES_ON_CHR(CURR,1)).stop]; end end else EXONS=[EXONS;genes(GENES_ON_CHR(CURR,1)).start,genes(GENES_ON_CHR(CURR,1)).stop]; end end end if not (isempty(MAX_STOP)) for CURR=(i+1):MAX_STOP if(not(isempty(genes(GENES_ON_CHR(CURR,1)).transcripts))) for tra=1:size(genes(GENES_ON_CHR(CURR,1)).transcripts,2) if(not(isempty(genes(GENES_ON_CHR(CURR,1)).exons))) EXONS=[EXONS;genes(GENES_ON_CHR(CURR,1)).exons{tra}]; else EXONS=[EXONS;genes(GENES_ON_CHR(CURR,1)).start,genes(GENES_ON_CHR(CURR,1)).stop]; end end else EXONS=[EXONS;genes(GENES_ON_CHR(CURR,1)).start,genes(GENES_ON_CHR(CURR,1)).stop]; end end end if not (isempty([MAX_STOP,MIN_START])) EXONS=EXONS(EXONS(:,2)>=STARTS(i),:); EXONS=EXONS(EXONS(:,1)<=STOPS(i),:); new_genes(GENES_ON_CHR(i,1)).non_unique_regions=EXONS; else new_genes(GENES_ON_CHR(i,1)).non_unique_regions=[]; end end COUNTER=COUNTER+1; end