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1 #!/usr/local/bin/python
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2 # hack to run and process a linkage format file into
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3 # the format used by Marchini's SNPTEST imputed case control association
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4 # expects args as
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5 # rgGTOOL.py $i $o $discrete $logf $outdir
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6 # ross lazarus
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7
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8 import sys,math,shutil,subprocess,os,time
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9 from os.path import abspath
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10 imagedir = '/static/rg' # if needed for images
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11 myversion = 'V000.1 August 2007'
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12
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13 def timenow():
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14 """return current time as a string
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15 """
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16 return time.strftime('%d/%m/%Y %H:%M:%S', time.localtime(time.time()))
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17
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18
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19
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20 if __name__ == "__main__":
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21 if len(sys.argv) < 6:
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22 s = 'rgGTOOL.py needs 5 params - got %s \n' % (sys.argv)
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23 sys.stderr.write(s) # print >>,s would probably also work?
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24 sys.exit(0)
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25 print 'Rgenetics %s http://rgenetics.org SNPTEST Tools, rgGTOOL.py starting at %s' % (myversion,timenow())
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26 pname = sys.argv[1]
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27 lpedname = pname.split('.ped')[0] # get file name part
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28 outname = sys.argv[2]
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29 discrete = sys.argv[3]
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30 logf = sys.argv[4]
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31 outdir = sys.argv[5]
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32 cdir = os.getcwd()
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33 me = sys.argv[0]
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34 mypath = abspath(os.path.join(cdir,me)) # get abs path to this python script
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35 shpath = abspath(os.path.sep.join(mypath.split(os.path.sep)[:-1]))
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36 alogf = abspath(os.path.join(cdir,logf)) # absolute paths
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37 apedf = abspath(os.path.join(cdir,'%s.ped' % lpedname)) # absolute paths
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38 amapf = abspath(os.path.join(cdir,'%s.map' % lpedname)) # absolute paths
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39 outg = abspath(os.path.join(outdir,'%s.gen' % outname)) # absolute paths
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40 outs = abspath(os.path.join(outdir,'%s.sample' % outname)) # absolute paths
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41 workdir = abspath(os.path.sep.join(mypath.split(os.path.sep)[:-1])) # trim end off './database/files/foo.dat'
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42 os.chdir(workdir)
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43 tlogname = '%s.logtemp' % outname
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44 sto = file(tlogname,'w')
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45 sto.write('rgGTOOL.py: called with %s\n' % (sys.argv))
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46 exme = 'gtool'
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47 vcl = [exme,'-P','--ped',apedf,'--map',amapf,'--discrete_phenotype',discrete,'--og',outg,'--os',outs]
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48 #'/usr/local/bin/plink','/usr/local/bin/plink',pc1,pc2,pc3)
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49 #os.spawnv(os.P_WAIT,plink,vcl)
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50 p=subprocess.Popen(' '.join(vcl),shell=True,stdout=sto)
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51 retval = p.wait()
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52 sto.write('rgGTOOL.py after calling %s: vcl=%s\n' % (exme,vcl))
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53 sto.close()
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54 shutil.move(tlogname,alogf)
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55 os.chdir(cdir)
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56
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57
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58
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