comparison tools/maf/maf_to_fasta_concat.py @ 0:9071e359b9a3

Uploaded
author xuebing
date Fri, 09 Mar 2012 19:37:19 -0500
parents
children
comparison
equal deleted inserted replaced
-1:000000000000 0:9071e359b9a3
1 #!/usr/bin/env python
2
3 """
4 Read a maf and output a single block fasta file, concatenating blocks
5
6 usage %prog species1,species2 maf_file out_file
7 """
8 #Dan Blankenberg
9 import sys
10 from galaxy import eggs
11 import pkg_resources; pkg_resources.require( "bx-python" )
12 from bx.align import maf
13 from galaxy.tools.util import maf_utilities
14
15 assert sys.version_info[:2] >= ( 2, 4 )
16
17 def __main__():
18 try:
19 species = maf_utilities.parse_species_option( sys.argv[1] )
20 except Exception, e:
21 maf_utilities.tool_fail( "Error determining species value: %s" % e )
22 try:
23 input_filename = sys.argv[2]
24 except Exception, e:
25 maf_utilities.tool_fail( "Error reading MAF filename: %s" % e )
26 try:
27 file_out = open( sys.argv[3], 'w' )
28 except Exception, e:
29 maf_utilities.tool_fail( "Error opening file for output: %s" % e )
30
31 if species:
32 print "Restricted to species: %s" % ', '.join( species )
33 else:
34 print "Not restricted to species."
35
36 if not species:
37 try:
38 species = maf_utilities.get_species_in_maf( input_filename )
39 except Exception, e:
40 maf_utilities.tool_fail( "Error determining species in input MAF: %s" % e )
41
42 for spec in species:
43 file_out.write( ">" + spec + "\n" )
44 try:
45 for start_block in maf.Reader( open( input_filename, 'r' ) ):
46 for block in maf_utilities.iter_blocks_split_by_species( start_block ):
47 block.remove_all_gap_columns() #remove extra gaps
48 component = block.get_component_by_src_start( spec ) #blocks only have one occurrence of a particular species, so this is safe
49 if component:
50 file_out.write( component.text )
51 else:
52 file_out.write( "-" * block.text_size )
53 except Exception, e:
54 maf_utilities.tool_fail( "Your MAF file appears to be malformed: %s" % e )
55 file_out.write( "\n" )
56 file_out.close()
57
58
59 if __name__ == "__main__": __main__()