comparison tools/maf/maf_to_fasta_multiple_sets.py @ 0:9071e359b9a3

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author xuebing
date Fri, 09 Mar 2012 19:37:19 -0500
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-1:000000000000 0:9071e359b9a3
1 #!/usr/bin/env python
2
3 """
4 Read a maf and output a multiple block fasta file.
5 """
6 #Dan Blankenberg
7 import sys
8 from galaxy import eggs
9 import pkg_resources; pkg_resources.require( "bx-python" )
10 from bx.align import maf
11 from galaxy.tools.util import maf_utilities
12
13 assert sys.version_info[:2] >= ( 2, 4 )
14
15 def __main__():
16 try:
17 maf_reader = maf.Reader( open( sys.argv[1] ) )
18 except Exception, e:
19 maf_utilities.tool_fail( "Error opening input MAF: %s" % e )
20 try:
21 file_out = open( sys.argv[2], 'w' )
22 except Exception, e:
23 maf_utilities.tool_fail( "Error opening file for output: %s" % e )
24 try:
25 species = maf_utilities.parse_species_option( sys.argv[3] )
26 if species:
27 num_species = len( species )
28 else:
29 num_species = 0
30 except Exception, e:
31 maf_utilities.tool_fail( "Error determining species value: %s" % e )
32 try:
33 partial = sys.argv[4]
34 except Exception, e:
35 maf_utilities.tool_fail( "Error determining keep partial value: %s" % e )
36
37 if species:
38 print "Restricted to species: %s" % ', '.join( species )
39 else:
40 print "Not restricted to species."
41
42 for block_num, block in enumerate( maf_reader ):
43 if species:
44 block = block.limit_to_species( species )
45 if len( maf_utilities.get_species_in_block( block ) ) < num_species and partial == "partial_disallowed": continue
46 spec_counts = {}
47 for component in block.components:
48 spec, chrom = maf_utilities.src_split( component.src )
49 if spec not in spec_counts:
50 spec_counts[ spec ] = 0
51 else:
52 spec_counts[ spec ] += 1
53 file_out.write( "%s\n" % maf_utilities.get_fasta_header( component, { 'block_index' : block_num, 'species' : spec, 'sequence_index' : spec_counts[ spec ] }, suffix = "%s_%i_%i" % ( spec, block_num, spec_counts[ spec ] ) ) )
54 file_out.write( "%s\n" % component.text )
55 file_out.write( "\n" )
56 file_out.close()
57
58 if __name__ == "__main__": __main__()