Mercurial > repos > xuebing > sharplabtool
view tools/maf/maf_to_interval.py @ 0:9071e359b9a3
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author | xuebing |
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date | Fri, 09 Mar 2012 19:37:19 -0500 |
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#!/usr/bin/env python """ Read a maf and output intervals for specified list of species. """ import sys, os from galaxy import eggs import pkg_resources; pkg_resources.require( "bx-python" ) from bx.align import maf from galaxy.tools.util import maf_utilities assert sys.version_info[:2] >= ( 2, 4 ) def __main__(): input_filename = sys.argv[1] output_filename = sys.argv[2] output_id = sys.argv[3] #where to store files that become additional output database_tmp_dir = sys.argv[4] primary_spec = sys.argv[5] species = sys.argv[6].split( ',' ) all_species = sys.argv[7].split( ',' ) partial = sys.argv[8] keep_gaps = sys.argv[9] out_files = {} if "None" in species: species = [] if primary_spec not in species: species.append( primary_spec ) if primary_spec not in all_species: all_species.append( primary_spec ) all_species.sort() for spec in species: if spec == primary_spec: out_files[ spec ] = open( output_filename, 'wb+' ) else: out_files[ spec ] = open( os.path.join( database_tmp_dir, 'primary_%s_%s_visible_interval_%s' % ( output_id, spec, spec ) ), 'wb+' ) out_files[ spec ].write( '#chrom\tstart\tend\tstrand\tscore\tname\t%s\n' % ( '\t'.join( all_species ) ) ) num_species = len( all_species ) file_in = open( input_filename, 'r' ) maf_reader = maf.Reader( file_in ) for i, m in enumerate( maf_reader ): for j, block in enumerate( maf_utilities.iter_blocks_split_by_species( m ) ): if len( block.components ) < num_species and partial == "partial_disallowed": continue sequences = {} for c in block.components: spec, chrom = maf_utilities.src_split( c.src ) if keep_gaps == 'remove_gaps': sequences[ spec ] = c.text.replace( '-', '' ) else: sequences[ spec ] = c.text sequences = '\t'.join( [ sequences.get( spec, '' ) for spec in all_species ] ) for spec in species: c = block.get_component_by_src_start( spec ) if c is not None: spec2, chrom = maf_utilities.src_split( c.src ) assert spec2 == spec, Exception( 'Species name inconsistancy found in component: %s != %s' % ( spec, spec2 ) ) out_files[ spec ].write( "%s\t%s\t%s\t%s\t%s\t%s\t%s\n" % ( chrom, c.forward_strand_start, c.forward_strand_end, c.strand, m.score, "%s_%s_%s" % (spec, i, j), sequences ) ) file_in.close() for file_out in out_files.values(): file_out.close() if __name__ == "__main__": __main__()