view ezBAMQC/src/htslib/NEWS @ 15:28cebcc7f774

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author cshl-bsr
date Wed, 30 Mar 2016 12:15:18 -0400
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Noteworthy changes in release 1.2.1  (3 February 2015)

* Reinstated hts_file_type() and FT_* macros, which were available until 1.1
  but briefly removed in 1.2.  This function is deprecated and will be removed
  in a future release -- you should use hts_detect_format() etc instead


Noteworthy changes in release 1.2  (2 February 2015)

* HTSlib now has a configure script which checks your build environment
  and allows for selection of optional extras.  See INSTALL for details

* By default, reference sequences are fetched from the EBI CRAM Reference
  Registry and cached in your $HOME cache directory.  This behaviour can
  be controlled by setting REF_PATH and REF_CACHE enviroment variables
  (see the samtools(1) man page for details)

* Numerous CRAM improvements:
  - Support for CRAM v3.0, an upcoming revision to CRAM supporting
    better compression and per-container checksums
  - EOF checking for v2.1 and v3.0 (similar to checking BAM EOF blocks)
  - Non-standard values for PNEXT and TLEN fields are now preserved
  - hts_set_fai_filename() now provides a reference file when encoding
  - Generated read names are now numbered from 1, rather than being
    labelled 'slice:record-in-slice'
  - Multi-threading and speed improvements

* New htsfile command for identifying file formats, and corresponding
  file format detection APIs

* New tabix --regions FILE, --targets FILE options for filtering via BED files

* Optional iRODS file access, disabled by default.  Configure with --with-irods
  to enable accessing iRODS data objects directly via 'irods:DATAOBJ'

* All occurences of 2^29 in the source have been eliminated, so indexing
  and querying against reference sequences larger than 512Mbp works (when
  using CSI indices)

* Support for plain GZIP compression in various places

* VCF header editing speed improvements

* Added seq_nt16_int[] (equivalent to the samtools API's bam_nt16_nt4_table)

* Reinstated faidx_fetch_nseq(), which was accidentally removed from 1.1.
  Now faidx_fetch_nseq() and faidx_nseq() are equivalent; eventually
  faidx_fetch_nseq() will be deprecated and removed [#156]

* Fixed bugs #141, #152, #155, #158, #159, and various memory leaks