Mercurial > repos > yufei-luo > s_mart
diff SMART/Java/Python/GetIntersection.py @ 38:2c0c0a89fad7
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author | m-zytnicki |
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date | Thu, 02 May 2013 09:56:47 -0400 |
parents | 94ab73e8a190 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/SMART/Java/Python/GetIntersection.py Thu May 02 09:56:47 2013 -0400 @@ -0,0 +1,164 @@ +#! /usr/bin/env python +# +# Copyright INRA-URGI 2009-2011 +# +# This software is governed by the CeCILL license under French law and +# abiding by the rules of distribution of free software. You can use, +# modify and/ or redistribute the software under the terms of the CeCILL +# license as circulated by CEA, CNRS and INRIA at the following URL +# "http://www.cecill.info". +# +# As a counterpart to the access to the source code and rights to copy, +# modify and redistribute granted by the license, users are provided only +# with a limited warranty and the software's author, the holder of the +# economic rights, and the successive licensors have only limited +# liability. +# +# In this respect, the user's attention is drawn to the risks associated +# with loading, using, modifying and/or developing or reproducing the +# software by the user in light of its specific status of free software, +# that may mean that it is complicated to manipulate, and that also +# therefore means that it is reserved for developers and experienced +# professionals having in-depth computer knowledge. Users are therefore +# encouraged to load and test the software's suitability as regards their +# requirements in conditions enabling the security of their systems and/or +# data to be ensured and, more generally, to use and operate it in the +# same conditions as regards security. +# +# The fact that you are presently reading this means that you have had +# knowledge of the CeCILL license and that you accept its terms. +# +from optparse import OptionParser +from commons.core.parsing.ParserChooser import ParserChooser +from commons.core.writer.TranscriptWriter import TranscriptWriter +from SMART.Java.Python.structure.Interval import Interval +from SMART.Java.Python.structure.Transcript import Transcript +from SMART.Java.Python.structure.Mapping import Mapping +from SMART.Java.Python.misc.Progress import Progress +from SMART.Java.Python.misc.UnlimitedProgress import UnlimitedProgress + +MINBIN = 3 +MAXBIN = 7 +REFERENCE = 0 +QUERY = 1 + +def getBin(start, end): + for i in range(MINBIN, MAXBIN + 1): + binLevel = 10 ** i + if int(start / binLevel) == int(end / binLevel): + return int(i * 10 ** (MAXBIN + 1) + int(start / binLevel)) + return int((MAXBIN + 1) * 10 ** (MAXBIN + 1)) + +def getOverlappingBins(start, end): + array = [] + bigBin = int((MAXBIN + 1) * 10 ** (MAXBIN + 1)) + for i in range(MINBIN, MAXBIN + 1): + binLevel = 10 ** i + array.append((int(i * 10 ** (MAXBIN + 1) + int(start / binLevel)), int(i * 10 ** (MAXBIN + 1) + int(end / binLevel)))) + array.append((bigBin, bigBin)) + return array + + +class GetIntersection(object): + + def __init__(self, verbosity): + self.verbosity = verbosity + self.nbQueries = 0 + self.nbRefs = 0 + self.nbWritten = 0 + self.bins = {} + + def setReferenceFile(self, fileName, format): + chooser = ParserChooser(self.verbosity) + chooser.findFormat(format) + self.refParser = chooser.getParser(fileName) + + def setQueryFile(self, fileName, format): + chooser = ParserChooser(self.verbosity) + chooser.findFormat(format) + self.queryParser = chooser.getParser(fileName) + + def setOutputFile(self, fileName): + self.writer = TranscriptWriter(fileName, "gff3", self.verbosity) + + def loadRef(self): + progress = UnlimitedProgress(10000, "Reading references", self.verbosity) + for transcript in self.refParser.getIterator(): + if transcript.__class__.__name__ == "Mapping": + transcript = transcript.getTranscript() + chromosome = transcript.getChromosome() + bin = getBin(transcript.getStart(), transcript.getEnd()) + if chromosome not in self.bins: + self.bins[chromosome] = {} + if bin not in self.bins[chromosome]: + self.bins[chromosome][bin] = [] + self.bins[chromosome][bin].append(transcript) + self.nbRefs += 1 + progress.inc() + progress.done() + + def _compareTranscript(self, queryTranscript): + queryChromosome = queryTranscript.getChromosome() + if queryChromosome not in self.bins: + return None + queryStart = queryTranscript.getStart() + queryEnd = queryTranscript.getEnd() + bins = getOverlappingBins(queryStart, queryEnd) + overlaps = [] + for binRange in bins: + for bin in range(binRange[0], binRange[1]+1): + if bin not in self.bins[queryChromosome]: + continue + for refTranscript in self.bins[queryChromosome][bin]: + newTranscript = queryTranscript.getIntersection(refTranscript) + if newTranscript != None: + overlaps.append(newTranscript) + if not overlaps: + return None + newTranscript = overlaps[0] + for transcript in overlaps[1:]: + newTranscript.merge(transcript) + return newTranscript + + def compare(self): + progress = UnlimitedProgress(10000, "Comparing queries", self.verbosity) + for queryTranscript in self.queryParser.getIterator(): + if queryTranscript.__class__.__name__ == "Mapping": + queryTranscript = queryTranscript.getTranscript() + progress.inc() + self.nbQueries += 1 + newTranscript = self._compareTranscript(queryTranscript) + if newTranscript != None: + self.writer.addTranscript(queryTranscript) + self.nbWritten += 1 + progress.done() + self.writer.close() + + def displayResults(self): + print "# queries: %d" % (self.nbQueries) + print "# refs: %d" % (self.nbRefs) + print "# written: %d" % (self.nbWritten) + + def run(self): + self.loadRef() + self.compare() + self.displayResults() + +if __name__ == "__main__": + + description = "Get Intersection v1.0.0: Shrink the first data set so that all bases covered by the first data set is also covered by the second data set. [Category: Data Comparison]" + + parser = OptionParser(description = description) + parser.add_option("-i", "--input1", dest="inputFileName1", action="store", type="string", help="query input file [compulsory] [format: file in transcript format given by -f]") + parser.add_option("-f", "--format1", dest="format1", action="store", type="string", help="format of previous file [compulsory] [format: transcript file format]") + parser.add_option("-j", "--input2", dest="inputFileName2", action="store", type="string", help="reference input file [compulsory] [format: file in transcript format given by -g]") + parser.add_option("-g", "--format2", dest="format2", action="store", type="string", help="format of previous file [compulsory] [format: transcript file format]") + parser.add_option("-o", "--output", dest="outputFileName", action="store", type="string", help="output file [format: output file in GFF3 format]") + parser.add_option("-v", "--verbosity", dest="verbosity", action="store", default=1, type="int", help="trace level [format: int]") + (options, args) = parser.parse_args() + + gi = GetIntersection(options.verbosity) + gi.setQueryFile(options.inputFileName1, options.format1) + gi.setReferenceFile(options.inputFileName2, options.format2) + gi.setOutputFile(options.outputFileName) + gi.run()