Mercurial > repos > yufei-luo > s_mart
diff commons/core/parsing/BedParser.py @ 36:44d5973c188c
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author | m-zytnicki |
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date | Tue, 30 Apr 2013 15:02:29 -0400 |
parents | 769e306b7933 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/commons/core/parsing/BedParser.py Tue Apr 30 15:02:29 2013 -0400 @@ -0,0 +1,139 @@ +# +# Copyright INRA-URGI 2009-2010 +# +# This software is governed by the CeCILL license under French law and +# abiding by the rules of distribution of free software. You can use, +# modify and/ or redistribute the software under the terms of the CeCILL +# license as circulated by CEA, CNRS and INRIA at the following URL +# "http://www.cecill.info". +# +# As a counterpart to the access to the source code and rights to copy, +# modify and redistribute granted by the license, users are provided only +# with a limited warranty and the software's author, the holder of the +# economic rights, and the successive licensors have only limited +# liability. +# +# In this respect, the user's attention is drawn to the risks associated +# with loading, using, modifying and/or developing or reproducing the +# software by the user in light of its specific status of free software, +# that may mean that it is complicated to manipulate, and that also +# therefore means that it is reserved for developers and experienced +# professionals having in-depth computer knowledge. Users are therefore +# encouraged to load and test the software's suitability as regards their +# requirements in conditions enabling the security of their systems and/or +# data to be ensured and, more generally, to use and operate it in the +# same conditions as regards security. +# +# The fact that you are presently reading this means that you have had +# knowledge of the CeCILL license and that you accept its terms. +# +import re +import sys +from SMART.Java.Python.structure.Interval import Interval +from commons.core.parsing.TranscriptListParser import TranscriptListParser +from SMART.Java.Python.structure.Transcript import Transcript + + +class BedParser(TranscriptListParser): + """A class that parses a BED file and create a transcript list""" + + + def __init__(self, fileName, verbosity = 0): + self.title = None + TranscriptListParser.__init__(self, fileName, verbosity) + + +# def __del__(self): +# super(BedParser, self).__del__() + + + def getFileFormats(): + return ["bed"] + getFileFormats = staticmethod(getFileFormats) + + + def skipFirstLines(self): + mark = self.handle.tell() + line = self.handle.readline() + line = line.strip() + m = re.search(r"^\s*track\s+name\s*=\s*(\S+)\s+", line) + if m != None: + self.title = m.group(1) + self.currentLineNb += 1 + else: + self.handle.seek(mark) + return + + + + + def parseLine(self, line): + m = re.search(r"^\s*(\S+)\t+(\d+)\t+(\d+)\s*$", line) + if m != None: + transcript = Transcript() + transcript.setChromosome(m.group(1)) + transcript.setStart(min(int(m.group(2)), int(m.group(3))-1)) + transcript.setEnd(max(int(m.group(2)), int(m.group(3))-1)) + transcript.setName("Unnamed") + transcript.setDirection(1) + return transcript + + m = re.search(r"^\s*(\S+)\t+(\d+)\t+(\d+)\t+([^\t]+)\s*$", line) + if m != None: + transcript = Transcript() + transcript.setChromosome(m.group(1)) + transcript.setStart(min(int(m.group(2)), int(m.group(3))-1)) + transcript.setEnd(max(int(m.group(2)), int(m.group(3))-1)) + transcript.setName(m.group(4)) + transcript.setDirection(1) + return transcript + + m = re.search(r"^\s*(\S+)\t+(\d+)\t+(\d+)\t+([^\t]+)\t+\d+\.?\d*\s*$", line) + if m != None: + transcript = Transcript() + transcript.setChromosome(m.group(1)) + transcript.setStart(min(int(m.group(2)), int(m.group(3))-1)) + transcript.setEnd(max(int(m.group(2)), int(m.group(3))-1)) + transcript.setName(m.group(4)) + transcript.setDirection(1) + return transcript + + m = re.search(r"^\s*(\S+)\t+(\d+)\t+(\d+)\t+([^\t]+)\t+\d+\t+([+-])\t+\d+\t+\d+\t+0\t+(\d+)\t+(\S+)\t+(\S+)\s*$", line) + if m == None: + raise Exception("\nLine %d '%s' does not has a BED format." % (self.currentLineNb, line)) + transcript = Transcript() + transcript.setChromosome(m.group(1)) + transcript.setStart(min(int(m.group(2)), int(m.group(3))-1)) + transcript.setEnd(max(int(m.group(2)), int(m.group(3))-1)) + transcript.setName(m.group(4)) + transcript.setDirection(m.group(5)) + nbExons = int(m.group(6)) + sizes = m.group(7).split(",") + starts = m.group(8).split(",") + + # check for comment in name + m = re.search(r"^([^\(]*)\((\S+)\)$", transcript.getName()) + if m != None: + transcript.setName(m.group(1)) + transcript.setTagValues(m.group(2), ";", "=") + + # check for nb occurrences in name + m = re.search(r"(.*)-(\d+)$", transcript.getName()) + if m != None: + transcript.setName(m.group(1)) + transcript.setOccurrence(int(m.group(2))) + + for i in range(nbExons): + exon = Interval(transcript) + exon.setStart(int(starts[i])+transcript.getStart()) + exon.setEnd(transcript.getStart()+int(starts[i])+int(sizes[i])-1) + exon.setSize(int(sizes[i])) + transcript.addExon(exon) + + if transcript.exons[0].getStart() != transcript.getStart(): + sys.exit("There is something wrong with the start of transcript line '%s': transcript starts at %d whereas first exon starts at %d" % (line.strip(), transcript.start, transcript.exons[0].start)) + if transcript.exons[-1].getEnd() != transcript.getEnd(): + sys.exit("There is something wrong with the end of transcript line '%s': transcript ends at %d whereas last exon ends at %d" % (line.strip(), transcript.end, transcript.exons[-1].end)) + + return transcript +