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view commons/core/sql/TableSeqAdaptator.py @ 6:769e306b7933
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author | yufei-luo |
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date | Fri, 18 Jan 2013 04:54:14 -0500 |
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# Copyright INRA (Institut National de la Recherche Agronomique) # http://www.inra.fr # http://urgi.versailles.inra.fr # # This software is governed by the CeCILL license under French law and # abiding by the rules of distribution of free software. You can use, # modify and/ or redistribute the software under the terms of the CeCILL # license as circulated by CEA, CNRS and INRIA at the following URL # "http://www.cecill.info". # # As a counterpart to the access to the source code and rights to copy, # modify and redistribute granted by the license, users are provided only # with a limited warranty and the software's author, the holder of the # economic rights, and the successive licensors have only limited # liability. # # In this respect, the user's attention is drawn to the risks associated # with loading, using, modifying and/or developing or reproducing the # software by the user in light of its specific status of free software, # that may mean that it is complicated to manipulate, and that also # therefore means that it is reserved for developers and experienced # professionals having in-depth computer knowledge. Users are therefore # encouraged to load and test the software's suitability as regards their # requirements in conditions enabling the security of their systems and/or # data to be ensured and, more generally, to use and operate it in the # same conditions as regards security. # # The fact that you are presently reading this means that you have had # knowledge of the CeCILL license and that you accept its terms. import sys from commons.core.sql.TableAdaptator import TableAdaptator from commons.core.sql.ITableSeqAdaptator import ITableSeqAdaptator from commons.core.coord.SetUtils import SetUtils from commons.core.seq.Bioseq import Bioseq ## Adaptator for a Seq table # class TableSeqAdaptator( TableAdaptator, ITableSeqAdaptator ): ## Retrieve all the distinct accession names in a list. # # @return lAccessions list of accessions # def getAccessionsList( self ): sqlCmd = "SELECT DISTINCT accession FROM %s;" % ( self._table ) lAccessions = self._getStringListWithSQLCmd(sqlCmd) return lAccessions ## Save sequences in a fasta file from a list of accession names. # # @param lAccessions list of accessions # @param outFileName string Fasta file # def saveAccessionsListInFastaFile( self, lAccessions, outFileName ): outFile = open( outFileName, "w" ) for ac in lAccessions: bs = self.getBioseqFromHeader( ac ) bs.write(outFile) outFile.close() ## Get a bioseq instance given its header # # @param header string name of the sequence ('accession' field in the 'seq' table) # @return bioseq instance # def getBioseqFromHeader( self, header ): sqlCmd = "SELECT * FROM %s WHERE accession='%s';" % ( self._table, header ) self._iDb.execute( sqlCmd ) res = self._iDb.fetchall() return Bioseq( res[0][0], res[0][1] ) ## Retrieve the length of a sequence given its name. # # @param accession name of the sequence # @return seqLength integer length of the sequence # def getSeqLengthFromAccession( self, accession ): sqlCmd = 'SELECT length FROM %s WHERE accession="%s"' % ( self._table, accession ) seqLength = self._iDb.getIntegerWithSQLCmd(sqlCmd) return seqLength ## Retrieve the length of a sequence given its description. # # @param description of the sequence # @return seqLength integer length of the sequence # def getSeqLengthFromDescription( self, description ): sqlCmd = 'SELECT length FROM %s WHERE description="%s"' % ( self._table, description ) seqLength = self._iDb.getIntegerWithSQLCmd(sqlCmd) return seqLength ## Retrieve all the accessions with length in a list of tuples # # @return lAccessionLengthTuples list of tuples # def getAccessionAndLengthList(self): sqlCmd = 'SELECT accession, length FROM %s' % self._table self._iDb.execute(sqlCmd) res = self._iDb.fetchall() lAccessionLengthTuples = [] for i in res: lAccessionLengthTuples.append(i) return lAccessionLengthTuples ## get subsequence according to given parameters # # @param accession # @param start integer # @param end integer # @return bioseq.sequence string # def getSubSequence( self, accession, start, end ): bs = Bioseq() if start <= 0 or end <= 0: print "ERROR with coordinates start=%i or end=%i" % ( start, end ) sys.exit(1) if accession not in self.getAccessionsList(): print "ERROR: accession '%s' absent from table '%s'" % ( accession, self._table ) sys.exit(1) lengthAccession = self.getSeqLengthFromAccession( accession ) if start > lengthAccession or end > lengthAccession: print "ERROR: coordinates start=%i end=%i out of sequence '%s' range (%i bp)" % ( start, end, accession, lengthAccession ) sys.exit(1) sqlCmd = "SELECT SUBSTRING(sequence,%i,%i) FROM %s WHERE accession='%s'" % ( min(start,end), abs(end-start)+ 1, self._table, accession ) self._iDb.execute( sqlCmd ) res = self._iDb.fetchall() bs.setSequence( res[0][0] ) if start > end: bs.reverseComplement() return bs.sequence ## get bioseq from given set list # # @param lSets set list of sets # @return bioseq instance # def getBioseqFromSetList( self, lSets ): header = "%s::%i %s " % ( lSets[0].name, lSets[0].id, lSets[0].seqname ) sequence = "" lSortedSets = SetUtils.getSetListSortedByIncreasingMinThenMax( lSets ) if not lSets[0].isOnDirectStrand(): lSortedSets.reverse() for iSet in lSortedSets: header += "%i..%i," % ( iSet.getStart(), iSet.getEnd() ) sequence += self.getSubSequence( iSet.seqname, iSet.getStart(), iSet.getEnd() ) return Bioseq( header[:-1], sequence ) ## Return True if the given accession is present in the table # def isAccessionInTable( self, name ): sqlCmd = "SELECT accession FROM %s WHERE accession='%s'" % ( self._table, name ) self._iDb.execute( sqlCmd ) res = self._iDb.fetchall() return bool(res) ## Retrieve all the distinct accession names in a fasta file. # # @param outFileName string Fasta file # def exportInFastaFile(self, outFileName ): lAccessions = self.getAccessionsList() self.saveAccessionsListInFastaFile( lAccessions, outFileName ) def _getStringListWithSQLCmd( self, sqlCmd ): self._iDb.execute(sqlCmd) res = self._iDb.fetchall() lString = [] for i in res: lString.append(i[0]) return lString def _getTypeAndAttr2Insert(self, bs): type2Insert = ( "'%s'", "'%s'", "'%s'", "'%i'" ) attr2Insert = (bs.header.split()[0], bs.sequence, bs.header, bs.getLength()) return type2Insert, attr2Insert def _escapeAntislash(self, obj): pass