Mercurial > repos > althonos > gecco
annotate CHANGELOG.md @ 5:169849dfb098 draft
"Release v0.8.6"
author | althonos |
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date | Thu, 17 Feb 2022 14:38:28 +0000 |
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1 # Changelog |
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2 All notable changes to this project will be documented in this file. |
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3 |
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4 The format is based on [Keep a Changelog](http://keepachangelog.com/en/1.0.0/) |
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5 and this project adheres to [Semantic Versioning](http://semver.org/spec/v2.0.0.html). |
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6 |
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7 ## [Unreleased] |
5 | 8 [Unreleased]: https://git.embl.de/grp-zeller/GECCO/compare/v0.8.6...master |
9 | |
10 ## [v0.8.6] - 2022-02-17 | |
11 [v0.8.6]: https://git.embl.de/grp-zeller/GECCO/compare/v0.8.5...v0.8.6 | |
12 ### Added | |
13 - CLI flag for enabling region masking for contigs processed by Prodigal. | |
14 - CLI flag for controlling region distance used for edge distance filtering. | |
15 ### Changed | |
16 - `gecco.model.Gene` and `gecco.model.Protein` are now immutable data classes. | |
17 - Bump minimum `pyrodigal` version to `v0.6.4` to use region masking. | |
18 - Implement filtering for extracted clusters based on distance to the contig edge. | |
19 - Store InterPro metadata file uncompressed for version-control integration. | |
20 ### Fixed | |
21 - Mark `BGC0000930` as `Terpene` in the type classifier data. | |
22 - Progress bar messages are now in consistent format. | |
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23 |
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24 ## [v0.8.5] - 2021-11-21 |
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25 [v0.8.5]: https://git.embl.de/grp-zeller/GECCO/compare/v0.8.4...v0.8.5 |
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26 ### Added |
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27 - Minimal compatibility support for running GECCO inside of Galaxy workflows. |
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28 |
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29 ## [v0.8.4] - 2021-09-26 |
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30 [v0.8.4]: https://git.embl.de/grp-zeller/GECCO/compare/v0.8.3-post1...v0.8.4 |
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31 ### Fixed |
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32 - `gecco convert gbk --format bigslice` failing to run because of outdated code ([#5](https://github.com/zellerlab/GECCO/issues/5)). |
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33 - `gecco convert gbk --format bigslice` not creating files with names conforming to BiG-SLiCE expected input. |
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34 ### Changed |
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35 - Bump minimum `pyrodigal` version to `v0.6.2` to use platform-accelerated code if supported. |
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36 |
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37 ## [v0.8.3-post1] - 2021-08-23 |
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38 [v0.8.3-post1]: https://git.embl.de/grp-zeller/GECCO/compare/v0.8.3...v0.8.3-post1 |
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39 ### Fixed |
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40 - Wrong default value for `--threshold` being shown in `gecco run` help message. |
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41 |
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42 ## [v0.8.3] - 2021-08-23 |
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43 [v0.8.3]: https://git.embl.de/grp-zeller/GECCO/compare/v0.8.2...v0.8.3 |
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44 ### Changed |
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45 - Default probability threshold for segmentation to 0.3 (from 0.4). |
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46 |
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47 ## [v0.9.0] - 2021-08-10 - **YANKED** |
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48 [v0.9.0]: https://git.embl.de/grp-zeller/GECCO/compare/v0.8.2...v0.9.0 |
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49 ### Changed |
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50 - Retrain internal model using `--select=0.35` instead of `--select=0.25` like before. |
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51 - Change default *p-value* filter from 1e-9 to 1e-5 to detect more features. |
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52 |
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53 ## [v0.8.2] - 2021-07-31 |
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54 [v0.8.2]: https://git.embl.de/grp-zeller/GECCO/compare/v0.8.1...v0.8.2 |
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55 ### Fixed |
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56 - `gecco run` crashing on Python 3.6 because of missing `contextlib.nullcontext` class. |
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57 ### Changed |
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58 - `gecco run` and `gecco annotate` will not try to count the number of profiles when given an external HMM file with the `--hmm` flag. |
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59 - `PyHMMER.run` now reports the *p-value* of each domain in addition to the *e-value* as a `/note` qualifier. |
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60 |
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61 ## [v0.8.1] - 2021-07-29 |
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62 [v0.8.1]: https://git.embl.de/grp-zeller/GECCO/compare/v0.8.0...v0.8.1 |
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63 ### Changed |
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64 - `gecco run` now filters out unneeded features before annotating, making it easier to analyze the results of a run with a custom `--model`. |
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65 ### Fixed |
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66 - `gecco` reporting about using Pfam `v33.1` while actually using `v34.0` because of an outdated field in `gecco/hmmer/Pfam.ini`. |
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67 ### Added |
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68 - Missing documentation for the `strand` attribute of `gecco.model.Gene`. |
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69 |
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70 ## [v0.8.0] - 2021-07-03 |
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71 [v0.8.0]: https://git.embl.de/grp-zeller/GECCO/compare/v0.7.0...v0.8.0 |
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72 ### Changed |
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73 - Retrain internal model using new sequence embeddings and remove broken/duplicate BGCs from MIBiG 2.0. |
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74 - Bump minimum `pyhmmer` version to `v0.4.0` to improve exception handling. |
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75 - Bump minimum `pyrodigal` version to `v0.5.0` to fix sequence decoding on some platforms. |
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76 - Use p-values instead of e-values to filter domains obtained with HMMER. |
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77 - `gecco cv` and `gecco train` now seed the RNG with a user-defined seed before shuffling rows of training data. |
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78 ### Fixed |
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79 - Extraction of BGC compositions for the type predictor while training. |
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80 - `ClusterCRF.trained` failing to open an external model. |
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81 ### Added |
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82 - `Domain.pvalue` attribute to access the p-value of a domain annotation. |
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83 - Mandatory `pvalue` column to `FeatureTable` objects. |
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84 - Support for loading several feature tables in `gecco train` and `gecco cv`. |
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85 - Warnings to `ClusterCRF.fit` when selecting uninformative features. |
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86 - `--correction` flag to `gecco train` and `gecco cv`, allowing to give a multiple testing correction method when computing p-values with the Fisher Exact Tests. |
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87 ### Removed |
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88 - Outdated `gecco embed` command. |
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89 - Unused `--truncate` flag from the `gecco train` CLI. |
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90 - Tigrfam domains, which is not improving performance on the new training data. |
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91 |
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92 ## [v0.7.0] - 2021-05-31 |
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93 [v0.7.0]: https://git.embl.de/grp-zeller/GECCO/compare/v0.6.3...v0.7.0 |
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94 ### Added |
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95 - Support for writing an AntiSMASH sideload JSON file after a `gecco run` workflow. |
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96 - Code for converting GenBank files in BiG-SLiCE compatible format with the `gecco convert` subcommand. |
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97 - Documentation about using GECCO in combination with AntiSMASH or BiG-SLiCE. |
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98 ### Changed |
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99 - Minimum Biopython version to `v1.73` for compatibility with older bioinformatics tooling. |
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100 - Internal domain composition shipped in the `gecco.types` with newer composition array obtained directly from MIBiG files. |
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101 ### Removed |
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102 - Outdated notice about `-vvv` verbosity level in the help message of the main `gecco` command. |
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103 |
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104 ## [v0.6.3] - 2021-05-10 |
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105 [v0.6.3]: https://git.embl.de/grp-zeller/GECCO/compare/v0.6.2...v0.6.3 |
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106 ### Fixed |
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107 - HMMER annotation not properly handling inputs with multiple contigs. |
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108 - Some progress bar totals displaying as floats in the CLI. |
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109 ### Changed |
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110 - `PyHMMER` now sets the `Z` and `domZ` values from the number of proteins given to the search pipeline. |
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111 - `gecco.cli` delegates imports to make CLI more responsive. |
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112 - `pkg_resources` has been replaced with `importlib.resources` and `importlib.metadata` where applicable. |
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113 - `multiprocessing.cpu_count` has been replaced with `os.cpu_count` where applicable. |
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114 |
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115 ## [v0.6.2] - 2021-05-04 |
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116 [v0.6.2]: https://git.embl.de/grp-zeller/GECCO/compare/v0.6.1...v0.6.2 |
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117 ### Fixed |
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118 - `gecco cv loto` crashing because of outdated code. |
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119 ### Changed |
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120 - Logging-style prompt will only display if GECCO is running with `-vv` flag. |
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121 ### Added |
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122 - GECCO bioRxiv paper reference to `Cluster.to_seq_record` output record. |
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123 |
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124 ## [v0.6.1] - 2021-03-15 |
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125 [v0.6.1]: https://git.embl.de/grp-zeller/GECCO/compare/v0.6.0...v0.6.1 |
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126 ### Fixed |
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127 - Progress bar not being disabled by `-q` flag in CLI. |
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128 - Fallback to using HMM name if accession is not available in `PyHMMER`. |
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129 - Group genes by source contig and process them separately in `PyHMMER` to avoid bogus E-values. |
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130 ### Added |
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131 - `psutil` dependency to get the number of physical CPU cores on the host machine. |
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132 - Support for using an arbitrary mapping of positives to negatives in `gecco embed`. |
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133 ### Removed |
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134 - Unused and outdated `HMMER` and `DomainRow` classes from `gecco.hmmer`. |
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135 |
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136 ## [v0.6.0] - 2021-02-28 |
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137 [v0.6.0]: https://git.embl.de/grp-zeller/GECCO/compare/v0.5.5...v0.6.0 |
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138 ### Changed |
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139 - Updated internal model with a cleaned-up version of the MIBiG-2.0 |
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140 Pfam-33.1/Tigrfam-15.0 embedding. |
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141 - Updated internal InterPro catalog. |
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142 ### Fixed |
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143 - Features not being grouped together in `gecco cv` and `gecco train` |
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144 when provided with a feature table where rows were not sorted by |
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145 protein IDs. |
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146 |
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147 ## [v0.5.5] - 2021-02-28 |
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148 [v0.5.5]: https://git.embl.de/grp-zeller/GECCO/compare/v0.5.4...v0.5.5 |
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149 ### Fixed |
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150 - `gecco cv` bug causing only the last fold to be written. |
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151 |
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152 ## [v0.5.4] - 2021-02-28 |
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153 [v0.5.4]: https://git.embl.de/grp-zeller/GECCO/compare/v0.5.3...v0.5.4 |
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154 ### Changed |
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155 - Replaced `verboselogs`, `coloredlogs` and `better-exceptions` with `rich`. |
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156 ### Removed |
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157 - `tqdm` training dependency. |
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158 ### Added |
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159 - `gecco annotate` command to produce a feature table from a genomic file. |
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160 - `gecco embed` to embed BGCs into non-BGC regions using feature tables. |
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161 |
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162 ## [v0.5.3] - 2021-02-21 |
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163 [v0.5.3]: https://git.embl.de/grp-zeller/GECCO/compare/v0.5.2...v0.5.3 |
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164 ### Fixed |
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165 - Coordinates of genes in output GenBank files. |
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166 - Potential issue with the number of CPUs in `PyHMMER.run`. |
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167 ### Changed |
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168 - Bump required `pyrodigal` version to `v0.4.2` to fix buffer overflow. |
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169 |
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170 ## [v0.5.2] - 2021-01-29 |
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171 [v0.5.2]: https://git.embl.de/grp-zeller/GECCO/compare/v0.5.1...v0.5.2 |
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172 ### Added |
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173 - Support for downloading HMM files directly from GitHub releases assets. |
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174 - Validation of filtered HMMs with MD5 checksum. |
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175 ### Fixed |
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176 - Invalid coordinates of protein domains in GenBank output files. |
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177 - `gecco.interpro` module not being added to wheel distribution. |
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178 ### Changed |
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179 - Bump required `pyhmmer` version to `v0.2.1`. |
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180 |
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181 ## [v0.5.1] - 2021-01-15 |
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182 [v0.5.1]: https://git.embl.de/grp-zeller/GECCO/compare/v0.5.0...v0.5.1 |
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183 ### Fixed |
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184 - `--hmm` flag being ignored in in `gecco run` command. |
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185 - `PyHMMER` using HMM names instead of accessions, causing issues with Pfam HMMs. |
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186 |
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187 ## [v0.5.0] - 2021-01-11 |
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188 [v0.5.0]: https://git.embl.de/grp-zeller/GECCO/compare/v0.4.5...v0.5.0 |
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189 ### Added |
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190 - Explicit support for Python 3.9. |
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191 ### Changed |
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192 - [`pyhmmer`](https://pypi.org/project/pyhmmer) is used to annotate protein sequences instead of HMMER3 binary `hmmsearch`. |
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193 - HMM files are stored in binary format to speedup parsing and reduce storage size. |
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194 - `tqdm` is now a *training*-only dependency. |
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195 - `gecco cv` now requires *training* dependencies. |
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196 |
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197 ## [v0.4.5] - 2020-11-23 |
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198 [v0.4.5]: https://git.embl.de/grp-zeller/GECCO/compare/v0.4.4...v0.4.5 |
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199 ### Added |
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200 - Additional `fold` column to cross-validation table output. |
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201 ### Changed |
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202 - Use sequence ID instead of protein ID to extract type from cluster in `gecco cv`. |
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203 - Install HMM data in pre-pressed format to make `hmmsearch` runs faster on short sequences. |
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204 - `gecco.orf` was rewritten to extract genes from input sequences in parallel. |
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205 |
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206 ## [v0.4.4] - 2020-09-30 |
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207 [v0.4.4]: https://git.embl.de/grp-zeller/GECCO/compare/v0.4.3...v0.4.4 |
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208 ### Added |
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209 - `gecco cv loto` command to run LOTO cross-validation using BGC types |
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210 for stratification. |
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211 - `header` keyword argument to `FeatureTable.dump` and `ClusterTable.dump` |
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212 to write the table without the column header allowing to append to an |
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213 existing table. |
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214 - `__getitem__` implementation for `FeatureTable` and `ClusterTable` |
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215 that returns a single row or a sub-table from a table. |
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216 ### Fixed |
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217 - `gecco cv` command now writes results iteratively instead of holding |
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218 the tables for every fold in memory. |
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219 ### Changed |
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220 - Bumped `pandas` training dependency to `v1.0`. |
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221 |
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222 ## [v0.4.3] - 2020-09-07 |
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223 [v0.4.3]: https://git.embl.de/grp-zeller/GECCO/compare/v0.4.2...v0.4.3 |
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224 ### Fixed |
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225 - GenBank files being written with invalid `/cds` feature type. |
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226 ### Changed |
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227 - Blocked installation of Biopython `v1.78` or newer as it removes `Bio.Alphabet` |
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228 and breaks the current code. |
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229 |
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230 ## [v0.4.2] - 2020-08-07 |
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231 [v0.4.2]: https://git.embl.de/grp-zeller/GECCO/compare/v0.4.1...v0.4.2 |
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232 ### Fixed |
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233 - `TypeClassifier.predict_types` using inverse type probabilities when |
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234 given several clusters to process. |
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235 |
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236 ## [v0.4.1] - 2020-08-07 |
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237 [v0.4.1]: https://git.embl.de/grp-zeller/GECCO/compare/v0.4.0...v0.4.1 |
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238 ### Fixed |
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239 - `gecco run` command crashing on input sequences not containing any genes. |
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240 |
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241 ## [v0.4.0] - 2020-08-06 |
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242 [v0.4.0]: https://git.embl.de/grp-zeller/GECCO/compare/v0.3.0...v0.4.0 |
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243 ### Added |
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244 - `gecco.model.ProductType` enum to model the biosynthetic class of a BGC. |
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245 ### Removed |
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246 - `pandas` interaction from internal data model. |
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247 - `ClusterCRF` code specific to cross-validation. |
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248 ### Changed |
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249 - `pandas`, `fisher` and `statsmodels` dependencies are now optional. |
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250 - `gecco train` command expects a cluster table in addition to the feature |
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251 table to know the types of the input BGCs. |
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252 |
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253 ## [v0.3.0] - 2020-08-03 |
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254 [v0.3.0]: https://git.embl.de/grp-zeller/GECCO/compare/v0.2.2...v0.3.0 |
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255 ### Changed |
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256 - Replaced Nearest-Neighbours classifier with Random Forest to perform type |
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257 prediction for candidate BGCs. |
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258 - `gecco.knn` module was renamed to implementation-agnostic name `gecco.types`. |
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259 ### Fixed |
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260 - Extraction of domain composition taking a long time in `gecco train` command. |
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261 ### Removed |
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262 - `--metric` argument to the `gecco run` CLI command. |
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263 |
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264 ## [v0.2.2] - 2020-07-31 |
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265 [v0.2.2]: https://git.embl.de/grp-zeller/GECCO/compare/v0.2.1...v0.2.2 |
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266 ### Changed |
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267 - `Domain` and `Gene` can now carry qualifiers that are used when they |
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268 are translated to a sequence feature. |
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269 ### Added |
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270 - InterPro names, accessions, and HMMER e-value for each annotated domain |
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271 in GenBank output files. |
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272 |
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273 ## [v0.2.1] - 2020-07-23 |
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274 [v0.2.1]: https://git.embl.de/grp-zeller/GECCO/compare/v0.2.0...v0.2.1 |
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275 ### Fixed |
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276 - Various potential crashes in `ClusterRefiner` code. |
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277 ### Removed |
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278 - Uneeded feature dictionary filtering in `ClusterCRF` for models with |
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279 Fisher Exact Test feature selection. |
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280 |
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281 ## [v0.2.0] - 2020-07-23 |
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282 [v0.2.0]: https://git.embl.de/grp-zeller/GECCO/compare/v0.1.1...v0.2.0 |
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283 ### Fixed |
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284 - `pandas` warning about unsorted columns in `gecco run`. |
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285 ### Removed |
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286 - `Gene.probability` property, replaced by `Gene.maximum_probability` and |
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287 `Gene.average_probability` properties to be explicit. |
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288 ### Changed |
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289 - Internal model now uses `Pfam` and `Tigrfam` with the top 35% features |
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290 selected with Fisher's Exact Test. |
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291 - `ClusterRefiner` now removes genes on `Cluster` edges if they do not |
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292 contain any domain annotation. |
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293 |
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294 ## [v0.1.1] - 2020-07-22 |
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295 [v0.1.1]: https://git.embl.de/grp-zeller/GECCO/compare/v0.1.0...v0.1.1 |
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296 ### Added |
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297 - `ClusterCRF.predict_probabilities` to annotate a list of `Gene`. |
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298 ### Changed |
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299 - BGC probability is now stored at the `Domain` level instead of at the `Gene` |
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300 level, independently of the feature extraction level used by the CRF. |
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301 - `ClusterKNN` will use the model path provided to `gecco run` if any. |
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302 ### Docs |
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303 - Added this changelog file to document changes in the code. |
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304 - Added documentation to `gecco` submodules missing some. |
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305 - Included the `CHANGELOG.md` file to the generated docs. |
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306 |
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307 ## [v0.1.0] - 2020-07-17 |
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308 [v0.1.0]: https://git.embl.de/grp-zeller/GECCO/compare/v0.0.1...v0.1.0 |
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309 Initial release. |
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310 |
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311 ## [v0.0.1] - 2018-08-13 |
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312 [v0.0.1]: https://git.embl.de/grp-zeller/GECCO/compare/37afb97...v0.0.1 |
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313 Proof-of-concept. |