Mercurial > repos > cstrittmatter > test_eurl_vtec_wgs_pt
diff data/amrfinder/changes.txt @ 3:0cbed1c0a762 draft default tip
planemo upload commit 15239f1674081ab51ab8dd75a9a40cf1bfaa93e8
| author | cstrittmatter |
|---|---|
| date | Tue, 28 Jan 2020 10:42:31 -0500 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/data/amrfinder/changes.txt Tue Jan 28 10:42:31 2020 -0500 @@ -0,0 +1,4729 @@ +--------------------------------------------------------------------- +Changes included in 2020-01-06.1 +--------------------------------------------------------------------- + +This update includes backward incompatible changes to the AMRFinderPlus +database format. It is compatible with AMRFinderPlus version 3.6. To use +this database version please update to AMRFinderPlus version 3.6. +See https://github.com/ncbi/amr/wiki/Upgrading for how to upgrade and +https://github.com/evolarjun/amr/wiki/AMRFinderPlus-database for information +on the new database format. + +Some highlights: + +- Database format has changed to allow AMRFinderPlus to detect promoter mutations and small indels + +- Many new point mutations, including Escherichia ampC promoter mutations, Klebsiella, and Enterococcus mutations + +- Small improvements to many product names + +- Improvements in class and subclass phenotype designations + +- Modifications and additions of a few HMMs + +- The usual addition of new alleles submitted to NCBI and others gleaned from the +literature + + + +- Protein and point mutations: + Total in prev: 6443 + Total in release: 6622 + Removed: 0 + Added: 184 + Protein Added: ABV01310.1 ltcA heat-labile_enterotoxin_LT_subunit_A + Protein Added: ADE89421.1 sslE lipoprotein_metalloprotease_SslE + Protein Added: ASK37426.1 aar AggR-activated_transcriptional_regulator_Aar + Protein Added: BAB41547.1 mepA multidrug_efflux_MATE_transporter_MepA + Protein Added: WP_000378442.1 emrR multidrug_efflux_transporter_EmrAB_transcriptional_repressor_EmrR + Protein Added: WP_001132507.1 acrB multidrug_efflux_RND_transporter_permease_subunit_AcrB + Protein Added: WP_002289153.1 liaR response_regulator_transcription_factor_LiaR + Protein Added: WP_002289154.1 liaS sensor_histidine_kinase_LiaS + Protein Added: WP_002289473.1 cls cardiolipin_synthase_Cls + Protein Added: WP_002295408.1 liaF three-component_signaling_pathway_regulator_LiaF + Protein Added: WP_002355137.1 liaR response_regulator_transcription_factor_LiaR + Protein Added: WP_002356022.1 yybT cyclic_dinucleotide_phosphodiesterase_YybT + Protein Added: WP_002365182.1 liaS sensor_histidine_kinase_LiaS + Protein Added: WP_002371880.1 parC DNA_topoisomerase_IV_subunit_A_ParC + Protein Added: WP_002381168.1 liaF three-component_signaling_pathway_regulator_LiaF + Protein Added: WP_002389492.1 gshF bifunctional_glutamate--cysteine_ligase/glutathione_synthetase_GshF + Protein Added: WP_002413481.1 cls cardiolipin_synthase_Cls + Protein Added: WP_002895659.1 pmrA two-component_system_response_regulator_PmrA + Protein Added: WP_002911375.1:47:mgrB_W47R mgrB PhoP/PhoQ_regulator_MgrB + Protein Added: WP_004147969.1 phoQ two-component_system_sensor_histidine_kinase_PhoQ + Protein Added: WP_004150807.1 phoP two-component_system_response_regulator_PhoP + Protein Added: WP_004179093.1 pmrB two-component_system_sensor_histidine_kinase_PmrB + Protein Added: WP_004184324.1 crrB HAMP_domain-containing_histidine_kinase_CrrB + Protein Added: WP_014906821.1 arnC undecaprenyl-phosphate_4-deoxy-4-formamido-L-arabinose_transferase_ArnC + Protein Added: WP_033554192.1 parE DNA_topoisomerase_IV_subunit_B_ParE + Protein Added: WP_033785346.1 gyrA DNA_gyrase_subunit_A_GyrA + Protein Added: WP_048324114.1 blaOKP-B-45 class_A_broad-spectrum_beta-lactamase_OKP-B-45 + Protein Added: WP_049003700.1 blaOKP-B-41 class_A_broad-spectrum_beta-lactamase_OKP-B-41 + Protein Added: WP_057012521.1 blaPFM-2 subclass_B2_metallo-beta-lactamase_PFM-2 + Protein Added: WP_060573544.1 blaACT-77 cephalosporin-hydrolyzing_class_C_beta-lactamase_ACT-77 + Protein Added: WP_060655783.1 blaOKP-B-36 class_A_broad-spectrum_beta-lactamase_OKP-B-36 + Protein Added: WP_064183695.1 blaOKP-B-16 class_A_broad-spectrum_beta-lactamase_OKP-B-16 + Protein Added: WP_080897395.1 blaOKP-D-1 class_A_broad-spectrum_beta-lactamase_OKP-D-1 + Protein Added: WP_086259262.1 acrB multidrug_efflux_RND_transporter_permease_subunit_AcrB + Protein Added: WP_087771722.1 blaOKP-B-34 class_A_broad-spectrum_beta-lactamase_OKP-B-34 + Protein Added: WP_087833272.1 blaOKP-B-21 class_A_broad-spectrum_beta-lactamase_OKP-B-21 + Protein Added: WP_100886243.1 blaOXA-895 OXA-229_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-895 + Protein Added: WP_101982161.1 parC DNA_topoisomerase_IV_subunit_A_ParC + Protein Added: WP_114508147.1 blaOKP-B-40 class_A_broad-spectrum_beta-lactamase_OKP-B-40 + Protein Added: WP_115256011.1 parC DNA_topoisomerase_IV_subunit_A_ParC + Protein Added: WP_117036963.1 gyrA DNA_gyrase_subunit_A_GyrA + Protein Added: WP_122543028.1 blaOKP-B-22 class_A_broad-spectrum_beta-lactamase_OKP-B-22 + Protein Added: WP_125353308.1 qnrB96 quinolone_resistance_pentapeptide_repeat_protein_QnrB96 + Protein Added: WP_130202201.1 blaVIM-69 subclass_B1_metallo-beta-lactamase_VIM-69 + Protein Added: WP_131419583.1 blaTEM-238 class_A_beta-lactamase_TEM-238 + Protein Added: WP_136034107.1 blaOKP-C-1 class_A_broad-spectrum_beta-lactamase_OKP-C-1 + Protein Added: WP_137277832.1 gyrA DNA_gyrase_subunit_A_GyrA + Protein Added: WP_156404644.1 blaADC-221 class_C_beta-lactamase_ADC-221 + Protein Added: WP_156404645.1 blaCMH-6 class_C_beta-lactamase_CMH-6 + Protein Added: WP_156404646.1 blaCMY-168 class_C_beta-lactamase_CMY-168 + Protein Added: WP_156404647.1 blaCMY-169 class_C_beta-lactamase_CMY-169 + Protein Added: WP_156404648.1 blaCMY-170 class_C_beta-lactamase_CMY-170 + Protein Added: WP_156404649.1 blaCTX-M-143 class_A_extended-spectrum_beta-lactamase_CTX-M-143 + Protein Added: WP_156404650.1 blaCTX-M-230 class_A_extended-spectrum_beta-lactamase_CTX-M-230 + Protein Added: WP_156404651.1 blaCTX-M-231 class_A_extended-spectrum_beta-lactamase_CTX-M-231 + Protein Added: WP_156404652.1 blaCTX-M-232 class_A_extended-spectrum_beta-lactamase_CTX-M-232 + Protein Added: WP_156404653.1 blaCTX-M-233 class_A_extended-spectrum_beta-lactamase_CTX-M-233 + Protein Added: WP_156404654.1 blaMOX-14 CMY-1/MOX_family_class_C_beta-lactamase_MOX-14 + Protein Added: WP_156404655.1 blaNDM-26 subclass_B1_metallo-beta-lactamase_NDM-26 + Protein Added: WP_156404656.1 blaNDM-29 subclass_B1_metallo-beta-lactamase_NDM-29 + Protein Added: WP_156404657.1 blaOKP-B-24 class_A_broad-spectrum_beta-lactamase_OKP-B-24 + Protein Added: WP_156404658.1 blaOXA-896 class_D_beta-lactamase_OXA-896 + Protein Added: WP_156404659.1 blaPER-14 class_A_extended-spectrum_beta-lactamase_PER-14 + Protein Added: WP_156404660.1 blaPFM-3 subclass_B2_metallo-beta-lactamase_PFM-3 + Protein Added: WP_156404661.1 blaSHV-115 class_A_extended-spectrum_beta-lactamase_SHV-115 + Protein Added: WP_156404662.1 blaVEB-23 class_A_extended-spectrum_beta-lactamase_VEB-23 + Protein Added: WP_156404663.1 blaVEB-24 class_A_extended-spectrum_beta-lactamase_VEB-24 + +Changes to existing protein and point mutation records: +Changed mepA accesssion: Q7A7N0.1 -> BAB41547.1 + Changed ltcA accession: ABV01314.1 -> ABV01310.1 + Changed aar accession: AVL28824.1 -> ASK37426.1 +Changed reference sequence for Escherichia parE point mutations: WP_000195296.1 -> WP_033554192.1 +Changed reference sequence for Escherichia acrB point mutations: WP_097509477.1 -> WP_086259262.1 + + 16S_A1055G NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_A1408G NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + subclass AMINOGLYCOSIDE -> GENTAMICIN C/NEOMYCIN/PAROMOMYCIN + 16S_A1499G NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_A1519C NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_A1519G NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_A1519T NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_A523C NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_A794G NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_A794T NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_A964G NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_C1054T NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_C1065T NC_003197.2 + genbank_nucleotide_accession -> AE006468.2 + genbank_strand_orientation -> + + 16S_C1066T NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_C1192T NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_C1192T NC_003197.2 + genbank_nucleotide_accession -> AE006468.2 + genbank_strand_orientation -> + + 16S_C528T NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_G1053A NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_G1058C NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_G1064A NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + subclass KANAMYCIN -> SPECTINOMYCIN + 16S_G1064C NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_G1064T NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_G1068A NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_G527T NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_G926A NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_G926C NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_G926T NC_000913.3 + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + 16S_T1406A NC_000913.3 + class AMINOGLYCOSIDE -> AMINGLYCOSIDE + genbank_nucleotide_accession -> U00096.3 + genbank_strand_orientation -> + + subclass G418 -> G418/TOBRAMYCIN + 23S_A2058G NC_004431.1 + genbank_nucleotide_accession -> AE014075.1 + genbank_strand_orientation -> + + subclass MACROLIDE -> AZITHROMYCIN/ERYTHROMYCIN/TELITHROMYCIN + 23S_A2058T NC_004431.1 + genbank_nucleotide_accession -> AE014075.1 + genbank_strand_orientation -> + + subclass MACROLIDE -> AZITHROMYCIN/ERYTHROMYCIN/TELITHROMYCIN + 23S_A2074C NC_002163.1 + genbank_nucleotide_accession -> AL111168.1 + genbank_strand_orientation -> + + 23S_A2074G NC_002163.1 + genbank_nucleotide_accession -> AL111168.1 + genbank_strand_orientation -> + + 23S_A2074T NC_002163.1 + genbank_nucleotide_accession -> AL111168.1 + genbank_strand_orientation -> + + 23S_A2075G NC_002163.1 + genbank_nucleotide_accession -> AL111168.1 + genbank_strand_orientation -> + + 23S_C2611T NC_004431.1 + genbank_nucleotide_accession -> AE014075.1 + genbank_strand_orientation -> + + subclass MACROLIDE -> ERYTHROMYCIN/TELITHROMYCIN + 23S_C2627A NC_002163.1 + genbank_nucleotide_accession -> AL111168.1 + genbank_strand_orientation -> + + 23S_G2032A NC_004431.1 + class MACROLIDE/OXAZOLIDINONE -> LINCOSAMIDE/OXAZOLIDINONE + genbank_nucleotide_accession -> AE014075.1 + genbank_strand_orientation -> + + subclass MACROLIDE/OXAZOLIDINONE -> CLINDAMYCIN/LINEZOLID + 23S_G2032C NC_004431.1 + genbank_nucleotide_accession -> AE014075.1 + genbank_strand_orientation -> + + subclass OXAZOLIDINONE -> LINEZOLID + 23S_G2032T NC_004431.1 + genbank_nucleotide_accession -> AE014075.1 + genbank_strand_orientation -> + + subclass MACROLIDE/OXAZOLIDINONE -> CLARITHROMYCIN/LINEZOLID + 23S_G2057A NC_004431.1 + class MACROLIDE/PHENICOL -> MULTIDRUG + genbank_nucleotide_accession -> AE014075.1 + genbank_strand_orientation -> + + subclass MACROLIDE/CHLORAMPHENICOL -> CHLORAMPHENICOL/ERYTHROMYCIN/TELITHROMYCIN + 23S_G2447T NC_004431.1 + genbank_nucleotide_accession -> AE014075.1 + genbank_strand_orientation -> + + subclass OXAZOLIDINONE -> LINEZOLID + 23S_T754A NC_004431.1 + genbank_nucleotide_accession -> AE014075.1 + genbank_strand_orientation -> + + subclass MACROLIDE -> ERYTHROMYCIN/TELITHROMYCIN + 50S_L22_A103C WP_002851214.1 + genbank_protein_accession -> CAL35796.1 + 50S_L22_A103V WP_002779996.1 + genbank_protein_accession -> AJW59082.1 + 50S_L22_A103V WP_002851214.1 + genbank_protein_accession -> CAL35796.1 + 50S_L22_A84D WP_002779996.1 + genbank_protein_accession -> AJW59082.1 + 50S_L22_A84D WP_002851214.1 + genbank_protein_accession -> CAL35796.1 + 50S_L22_A88E WP_002779996.1 + genbank_protein_accession -> AJW59082.1 + 50S_L22_A88E WP_002851214.1 + genbank_protein_accession -> CAL35796.1 + 50S_L22_G86E WP_002779996.1 + genbank_protein_accession -> AJW59082.1 + 50S_L22_G86E WP_002851214.1 + genbank_protein_accession -> CAL35796.1 + 50S_L22_G86V WP_002779996.1 + genbank_protein_accession -> AJW59082.1 + 50S_L22_G86V WP_002851214.1 + genbank_protein_accession -> CAL35796.1 + astA AAA20885.1 + class VIRULENCE -> + subclass astA -> + arsB AAA21095.1 + blacklisted_taxa Escherichia -> + arsC AAA21096.1 + blacklisted_taxa Escherichia -> + arsB AAA25637.1 + blacklisted_taxa Staphylococcus -> + arsB AAA27588.1 + blacklisted_taxa Staphylococcus -> + arsC AAB09628.1 + blacklisted_taxa Escherichia -> + ehxA AAC24352.1 + product_name enterohemolysin -> enterohemolysin EhxA + astA AAD43578.1 + class VIRULENCE -> + subclass astA -> + astA AAD43579.1 + class VIRULENCE -> + subclass astA -> + astA AAM88299.1 + class VIRULENCE -> + subclass astA -> + ehxA AAZ76497.1 + product_name enterohemolysin -> enterohemolysin EhxA + ehxA ABQ02442.1 + product_name enterohemolysin -> enterohemolysin EhxA + ehxA ABQ02443.1 + product_name enterohemolysin -> enterohemolysin EhxA + ehxA ABQ02445.1 + product_name enterohemolysin -> enterohemolysin EhxA + ehxA ABQ02447.1 + product_name enterohemolysin -> enterohemolysin EhxA + ehxA ABQ02448.1 + product_name enterohemolysin -> enterohemolysin EhxA + emrD3 ABQ18953.1 + blacklisted_taxa Vibrio_cholerae -> + kdeA ABR76310.1 + blacklisted_taxa Klebsiella -> + class -> EFFLUX + subclass -> EFFLUX + ehxA ACL51961.1 + product_name enterohemolysin -> enterohemolysin EhxA + emrD ACN65732.1 + class -> EFFLUX + subclass -> EFFLUX + amvA ACQ82816.1 + class -> EFFLUX + subclass -> EFFLUX + astA ADI59685.1 + class VIRULENCE -> + subclass astA -> + ehxA ADZ45128.1 + product_name enterohemolysin -> enterohemolysin EhxA + asr BAA15331.2 + blacklisted_taxa Escherichia -> + arsB BAA24823.1 + blacklisted_taxa Escherichia -> + arsC BAA24824.1 + blacklisted_taxa Escherichia, Klebsiella -> + ehxA BAA31774.1 + product_name enterohemolysin -> enterohemolysin EhxA + fieF BAB89353.1 + blacklisted_taxa Klebsiella -> + fieF BAE77395.1 + blacklisted_taxa Escherichia, Salmonella -> + emrD BAE77620.1 + blacklisted_taxa Escherichia -> + class -> EFFLUX + subclass -> EFFLUX + arsR BAE77793.1 + blacklisted_taxa Escherichia -> + ehxA CAA63849.1 + product_name enterohemolysin -> enterohemolysin EhxA + emrD EFF04178.1 + class -> EFFLUX + subclass -> EFFLUX + silF KGL71342.1 + product_name Ag(+)/Cu(+) efflux RND transporter periplasmic metallochaperone SilF -> Cu(+)/Ag(+) efflux RND transporter periplasmic metallochaperone SilF + dfrA18 WP_001031075.1 + product_name trimethoprim-resistant dihydrofolate reductase Dfr18 -> trimethoprim-resistant dihydrofolate reductase DfrA18 + mphK WP_003246254.1 + product_name macrolide 2'-phosphotransferase MphJ -> macrolide 2'-phosphotransferase MphK + blaOKP-B-6 WP_004205995.1 + gene_family blaOKP -> blaOKP-B + ampC WP_006178946.1 + product_name CMY2/MIR/ACT/EC family class c beta-lactamase -> CMY2/MIR/ACT/EC family class C beta-lactamase + blaOKP-B-8 WP_017900346.1 + gene_family blaOKP -> blaOKP-B + blaOKP-A-17 WP_023289605.1 + gene_family blaOKP -> blaOKP-A + blaOKP-B-23 WP_023318187.1 + gene_family blaOKP -> blaOKP-B + blaOKP-A-2 WP_032452758.1 + gene_family blaOKP -> blaOKP-A + blaOKP-B-1 WP_032456002.1 + gene_family blaOKP -> blaOKP-B + blaPAC-1 WP_034051940.1 + product_name class C beta-lactamase PAC-1 -> inhibitior-resistant cephalosporin-hydrolyzing class C beta-lactamase PAC-1 + subclass BETA-LACTAM -> CEPHALOSPORIN + blaOKP-A-3 WP_044522859.1 + gene_family blaOKP -> blaOKP-A + blaOKP-A-8 WP_048334865.1 + gene_family blaOKP -> blaOKP-A + blaOKP-B-7 WP_057215100.1 + gene_family blaOKP -> blaOKP-B + ampC WP_057991970.1 + product_name class C beta-lactamase -> MCA family class C beta-lactamase + blaOKP-A-6 WP_060590773.1 + gene_family blaOKP -> blaOKP-A + ampC WP_063406924.1 + product_name CMY2/MIR/ACT/EC family class c beta-lactamase -> CMY2/MIR/ACT/EC family class C beta-lactamase + blaOKP-B WP_063842745.1 + gene_family blaOKP -> blaOKP-B + blaOKP-A-1 WP_063860896.1 + gene_family blaOKP -> blaOKP-A + blaOKP-A-10 WP_063860897.1 + gene_family blaOKP -> blaOKP-A + blaOKP-A-11 WP_063860898.1 + gene_family blaOKP -> blaOKP-A + blaOKP-A-12 WP_063860899.1 + gene_family blaOKP -> blaOKP-A + blaOKP-A-13 WP_063860900.1 + gene_family blaOKP -> blaOKP-A + blaOKP-A-14 WP_063860901.1 + gene_family blaOKP -> blaOKP-A + blaOKP-A-15 WP_063860902.1 + gene_family blaOKP -> blaOKP-A + blaOKP-A-16 WP_063860903.1 + gene_family blaOKP -> blaOKP-A + blaOKP-A-4 WP_063860904.1 + gene_family blaOKP -> blaOKP-A + blaOKP-A-5 WP_063860905.1 + gene_family blaOKP -> blaOKP-A + blaOKP-A-7 WP_063860906.1 + gene_family blaOKP -> blaOKP-A + blaOKP-A-9 WP_063860907.1 + gene_family blaOKP -> blaOKP-A + blaOKP-B-10 WP_063860908.1 + gene_family blaOKP -> blaOKP-B + blaOKP-B-11 WP_063860909.1 + gene_family blaOKP -> blaOKP-B + blaOKP-B-13 WP_063860910.1 + gene_family blaOKP -> blaOKP-B + blaOKP-B-17 WP_063860911.1 + gene_family blaOKP -> blaOKP-B + blaOKP-B-18 WP_063860912.1 + gene_family blaOKP -> blaOKP-B + blaOKP-B-19 WP_063860913.1 + gene_family blaOKP -> blaOKP-B + blaOKP-B-2 WP_063860914.1 + gene_family blaOKP -> blaOKP-B + blaOKP-B-20 WP_063860915.1 + gene_family blaOKP -> blaOKP-B + blaOKP-B-3 WP_063860916.1 + gene_family blaOKP -> blaOKP-B + blaOKP-B-4 WP_063860917.1 + gene_family blaOKP -> blaOKP-B + blaOKP-B-5 WP_063860923.1 + gene_family blaOKP -> blaOKP-B + blaOKP-B-9 WP_063860931.1 + gene_family blaOKP -> blaOKP-B + icr-Mo WP_082741435.1 + class -> COLISTIN + subclass -> COLISTIN + blaPDC-245 WP_100831609.1 + product_name class C beta-lactamase PDC-245 -> inhibitor-resistant class C beta-lactamase PDC-245 + blaPDC-270 WP_109791203.1 + product_name class C beta-lactamase PDC-270 -> inhibitor-resistant class C beta-lactamase PDC-270 + blaPDC-322 WP_138403314.1 + product_name class C beta-lactamase PDC-322 -> inhibitor-resistant class C beta-lactamase PDC-322 + blaKPC-41 WP_148044419.1 + product_name carbapenem-hydrolyzing class A beta-lactamase KPC-41 -> inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-41 + blaPDC-346 WP_148044438.1 + product_name class C beta-lactamase PDC-346 -> inhibitor-resistant class C beta-lactamase PDC-346 + blaPDC-381 WP_148044467.1 + product_name class C beta-lactamase PDC-381 -> inhibitor-resistant class C beta-lactamase PDC-381 + acrR_R45C WP_000101737.1 + genbank_protein_accession -> AAC73566.1 + product_name transcriptional regulator -> transcriptional regulator AcrR + basR_G15R WP_094970923.1 + genbank_protein_accession -> OZX69954.1 + basR_G53A WP_094970923.1 + genbank_protein_accession -> OZX69954.1 + basR_G53C WP_094970923.1 + genbank_protein_accession -> OZX69954.1 + basR_G53E WP_094970923.1 + genbank_protein_accession -> OZX69954.1 + basR_G53R WP_094970923.1 + genbank_protein_accession -> OZX69954.1 + basR_G53S WP_094970923.1 + genbank_protein_accession -> OZX69954.1 + basR_G53V WP_094970923.1 + genbank_protein_accession -> OZX69954.1 + basR_G53W WP_094970923.1 + genbank_protein_accession -> OZX69954.1 + basR_L105P WP_094970923.1 + genbank_protein_accession -> OZX69954.1 + basR_R81L WP_094970923.1 + genbank_protein_accession -> OZX69954.1 + basR_R81S WP_094970923.1 + genbank_protein_accession -> OZX69954.1 + basR_S39I WP_094970923.1 + genbank_protein_accession -> OZX69954.1 + cmeR_G86A WP_002843095.1 + genbank_protein_accession -> EAH9016342.1 + cyaA_S352T WP_000281668.1 + genbank_protein_accession -> CDJ73082.1 + product_name adenylate cyclase -> adenylate cyclase CyaA + fabG_Y151V WP_001718014.1 + genbank_protein_accession -> EMW23334.1 + product_name beta-ketoacyl-ACP reductase -> beta-ketoacyl-ACP reductase FabG + fabI_F203A WP_000506490.1 + genbank_protein_accession -> AAC74370.1 + fabI_F203C WP_000506490.1 + genbank_protein_accession -> AAC74370.1 + fabI_F203L WP_000506490.1 + genbank_protein_accession -> AAC74370.1 + fabI_G93A WP_000506490.1 + genbank_protein_accession -> AAC74370.1 + fabI_G93S WP_000506490.1 + genbank_protein_accession -> AAC74370.1 + fabI_G93V WP_000506490.1 + genbank_protein_accession -> AAC74370.1 + folP_P64A WP_000764731.1 + genbank_protein_accession -> GDV24718.1 + product_name dihydropteroate synthase -> dihydropteroate synthase FolP + folP_P64H WP_000764731.1 + genbank_protein_accession -> GDV24718.1 + product_name dihydropteroate synthase -> dihydropteroate synthase FolP + folP_P64L WP_000764731.1 + genbank_protein_accession -> GDV24718.1 + product_name dihydropteroate synthase -> dihydropteroate synthase FolP + folP_P64R WP_000764731.1 + genbank_protein_accession -> GDV24718.1 + product_name dihydropteroate synthase -> dihydropteroate synthase FolP + folP_P64S WP_000764731.1 + genbank_protein_accession -> GDV24718.1 + product_name dihydropteroate synthase -> dihydropteroate synthase FolP + gyrA_A119E WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_A119S WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_A119V WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_A131G WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_A196E WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_A51V WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_A67P WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_A67S WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_A70T WP_002857904.1 + genbank_protein_accession -> CAL35145.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_A84P WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_A84V WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D72G WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D82G WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D82G WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D82N WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D85Y WP_002857904.1 + genbank_protein_accession -> CAL35145.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D87G WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D87G WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D87H WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D87K WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D87N WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D87N WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D87V WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D87Y WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D87Y WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D90A WP_002857904.1 + genbank_protein_accession -> CAL35145.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D90N WP_002779062.1 + genbank_protein_accession -> AJW58405.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D90N WP_002857904.1 + genbank_protein_accession -> CAL35145.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D90T WP_002857904.1 + genbank_protein_accession -> CAL35145.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D90Y WP_002779062.1 + genbank_protein_accession -> AJW58405.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_D90Y WP_002857904.1 + genbank_protein_accession -> CAL35145.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_E139A WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_G81C WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_G81C WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_G81D WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_G81H WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_G81S WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_H80P WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_L98V WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_N57K WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_P104S WP_002779062.1 + genbank_protein_accession -> AJW58405.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_P104S WP_002857904.1 + genbank_protein_accession -> CAL35145.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_Q106H WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_Q106R WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_S83A WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_S83A WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_S83F WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_S83F WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_S83I WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_S83L WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_S83V WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_S83W WP_001281243.1 + genbank_protein_accession -> AXO84158.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_S83Y WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_S97P WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_T86A WP_002779062.1 + genbank_protein_accession -> AJW58405.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_T86A WP_002857904.1 + genbank_protein_accession -> CAL35145.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_T86I WP_002779062.1 + genbank_protein_accession -> AJW58405.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_T86I WP_002857904.1 + genbank_protein_accession -> CAL35145.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_T86K WP_002779062.1 + genbank_protein_accession -> AJW58405.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_T86K WP_002857904.1 + genbank_protein_accession -> CAL35145.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_T86V WP_002779062.1 + genbank_protein_accession -> AJW58405.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_T86V WP_002857904.1 + genbank_protein_accession -> CAL35145.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrA_V73I WP_001281271.1 + genbank_protein_accession -> EAB4993534.1 + product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA + gyrB_D426N WP_000072067.1 + genbank_protein_accession -> BAE77595.1 + product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB + gyrB_E466D WP_000072047.1 + genbank_protein_accession -> AHP21689.1 + product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB + gyrB_K447E WP_000072067.1 + genbank_protein_accession -> BAE77595.1 + product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB + subclass QUINOLONE -> NALIDIXIC ACID + gyrB_R136C WP_000072067.1 + genbank_protein_accession -> BAE77595.1 + product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB + gyrB_R136E WP_000072067.1 + genbank_protein_accession -> BAE77595.1 + product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB + gyrB_R136G WP_000072067.1 + genbank_protein_accession -> BAE77595.1 + product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB + gyrB_R136H WP_000072067.1 + genbank_protein_accession -> BAE77595.1 + product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB + gyrB_R136I WP_000072067.1 + genbank_protein_accession -> BAE77595.1 + product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB + gyrB_R136L WP_000072067.1 + genbank_protein_accession -> BAE77595.1 + product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB + gyrB_R136S WP_000072067.1 + genbank_protein_accession -> BAE77595.1 + product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB + gyrB_R438L WP_000072047.1 + genbank_protein_accession -> AHP21689.1 + product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB + gyrB_S464F WP_000072047.1 + genbank_protein_accession -> AHP21689.1 + product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB + subclass QUINOLONE -> CIPROFLOXACIN + gyrB_S464Y WP_000072047.1 + genbank_protein_accession -> AHP21689.1 + product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB + subclass QUINOLONE -> CIPROFLOXACIN + gyrB_Y421C WP_000072047.1 + genbank_protein_accession -> AHP21689.1 + product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB + lon_P403L WP_001295325.1 + genbank_protein_accession -> EQY31068.1 + marR_A70T WP_000843414.1 + genbank_protein_accession -> AAC74603.2 + product_name MarR family transcriptional regulator -> transcriptional regulator MarR + marR_E31STOP WP_000843414.1 + genbank_protein_accession -> AAC74603.2 + product_name MarR family transcriptional regulator -> transcriptional regulator MarR + marR_I49S WP_000843414.1 + genbank_protein_accession -> AAC74603.2 + product_name MarR family transcriptional regulator -> transcriptional regulator MarR + marR_L78M WP_000843414.1 + genbank_protein_accession -> AAC74603.2 + product_name MarR family transcriptional regulator -> transcriptional regulator MarR + marR_R73C WP_000843414.1 + genbank_protein_accession -> AAC74603.2 + product_name MarR family transcriptional regulator -> transcriptional regulator MarR + marR_R73S WP_000843414.1 + genbank_protein_accession -> AAC74603.2 + product_name MarR family transcriptional regulator -> transcriptional regulator MarR + marR_R77C WP_000843414.1 + genbank_protein_accession -> AAC74603.2 + product_name MarR family transcriptional regulator -> transcriptional regulator MarR + marR_R77L WP_000843414.1 + genbank_protein_accession -> AAC74603.2 + product_name MarR family transcriptional regulator -> transcriptional regulator MarR + marR_R94H WP_000843414.1 + genbank_protein_accession -> AAC74603.2 + product_name MarR family transcriptional regulator -> transcriptional regulator MarR + marR_R94S WP_000843414.1 + genbank_protein_accession -> AAC74603.2 + product_name MarR family transcriptional regulator -> transcriptional regulator MarR + marR_S3N WP_000843414.1 + genbank_protein_accession -> AAC74603.2 + product_name MarR family transcriptional regulator -> transcriptional regulator MarR + marR_V45E WP_000843414.1 + genbank_protein_accession -> AAC74603.2 + product_name MarR family transcriptional regulator -> transcriptional regulator MarR + marR_V96E WP_000843414.1 + genbank_protein_accession -> AAC74603.2 + product_name MarR family transcriptional regulator -> transcriptional regulator MarR + murA_C115D WP_000357259.1 + genbank_protein_accession -> AIL15701.1 + product_name UDP-N-acetylglucosamine 1-carboxyvinyltransferase -> UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA + murA_C115E WP_000357259.1 + genbank_protein_accession -> AIL15701.1 + product_name UDP-N-acetylglucosamine 1-carboxyvinyltransferase -> UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA + murA_C115S WP_000357259.1 + genbank_protein_accession -> AIL15701.1 + product_name UDP-N-acetylglucosamine 1-carboxyvinyltransferase -> UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA + murA_D396N WP_000357259.1 + genbank_protein_accession -> AIL15701.1 + product_name UDP-N-acetylglucosamine 1-carboxyvinyltransferase -> UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA + murA_L370I WP_000357259.1 + genbank_protein_accession -> AIL15701.1 + product_name UDP-N-acetylglucosamine 1-carboxyvinyltransferase -> UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA + nfsA_G131D WP_089631889.1 + genbank_protein_accession -> OYN67948.1 + subclass NITROFURAN -> NITROFURANTOIN + nfsA_K141STOP WP_089631889.1 + genbank_protein_accession -> OYN67948.1 + subclass NITROFURAN -> NITROFURANTOIN + nfsA_Q44STOP WP_089631889.1 + genbank_protein_accession -> OYN67948.1 + subclass NITROFURAN -> NITROFURANTOIN + nfsA_R133S WP_089631889.1 + genbank_protein_accession -> OYN67948.1 + subclass NITROFURAN -> NITROFURANTOIN + nfsA_R15C WP_089631889.1 + genbank_protein_accession -> OYN67948.1 + subclass NITROFURAN -> NITROFURANTOIN + nfsA_R203C WP_089631889.1 + genbank_protein_accession -> OYN67948.1 + subclass NITROFURAN -> NITROFURANTOIN + nfsA_R203L WP_089631889.1 + genbank_protein_accession -> OYN67948.1 + subclass NITROFURAN -> NITROFURANTOIN + nfsA_S33R WP_089631889.1 + genbank_protein_accession -> OYN67948.1 + subclass NITROFURAN -> NITROFURANTOIN + ompF_G141D WP_000977920.1 + genbank_protein_accession -> AAC74015.1 + product_name outer membrane protein F -> outer membrane protein F OmpF + ompF_G141E WP_000977920.1 + genbank_protein_accession -> AAC74015.1 + product_name outer membrane protein F -> outer membrane protein F OmpF + parC_A108T WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_A108V WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_A56T WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_A85T WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_D111H WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_E84A WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_E84G WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_E84G WP_001281910.1 + genbank_protein_accession -> EAW2725281.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_E84K WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_E84K WP_001281910.1 + genbank_protein_accession -> EAW2725281.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_E84V WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_F60I WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_F60L WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_G78D WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_G78D WP_001281910.1 + genbank_protein_accession -> EAW2725281.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_G78K WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_S129P WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_S57T WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_S80F WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_S80I WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_S80I WP_001281910.1 + genbank_protein_accession -> EAW2725281.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_S80L WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_S80R WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_S80R WP_001281910.1 + genbank_protein_accession -> EAW2725281.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_S80Y WP_001281881.1 + genbank_protein_accession -> AAC76055.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_T66I WP_001281910.1 + genbank_protein_accession -> EAW2725281.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parC_W106G WP_001281910.1 + genbank_protein_accession -> EAW2725281.1 + product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC + parE_A499T WP_000195318.1 + genbank_protein_accession -> ATQ05934.1 + product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE + parE_E454G WP_000195318.1 + genbank_protein_accession -> ATQ05934.1 + product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE + parE_H462Y WP_000195318.1 + genbank_protein_accession -> ATQ05934.1 + product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE + parE_M438I WP_000195318.1 + genbank_protein_accession -> ATQ05934.1 + product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE + parE_S458P WP_000195318.1 + genbank_protein_accession -> ATQ05934.1 + product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE + parE_V461G WP_000195318.1 + genbank_protein_accession -> ATQ05934.1 + product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE + parE_V514G WP_000195318.1 + genbank_protein_accession -> ATQ05934.1 + product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE + parE_V521F WP_000195318.1 + genbank_protein_accession -> ATQ05934.1 + product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE + pmrA_G15R WP_000697899.1 + genbank_protein_accession -> EAB2345955.1 + pmrA_G53E WP_000697899.1 + genbank_protein_accession -> EAB2345955.1 + pmrA_G53R WP_000697899.1 + genbank_protein_accession -> EAB2345955.1 + pmrA_R81C WP_000697899.1 + genbank_protein_accession -> EAB2345955.1 + pmrA_R81H WP_000697899.1 + genbank_protein_accession -> EAB2345955.1 + pmrB_A159P WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_A159V WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_C84R WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_C84Y WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_E121A WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_E121K WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_E121Q WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_E166K WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_E166K WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_G206D WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_G206R WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_G206W WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_L10P WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_L10R WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_L14F WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_L14R WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_L14S WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_L22P WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_M186I WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_N130Y WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_P94L WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_P94Q WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_P94Q WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_P94S WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_R155P WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_S124P WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_S29R WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_S305R WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_T147A WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_T147P WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_T156M WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_T156M WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_T156P WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_T92A WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_V161G WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_V161G WP_001300761.1 + genbank_protein_accession -> KHH69629.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_V161L WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + pmrB_V161M WP_001212189.1 + genbank_protein_accession -> EAM5131532.1 + product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB + ptsI_V25I WP_000623140.1 + genbank_protein_accession -> CDJ72759.1 + product_name phosphoenolpyruvate--protein phosphotransferase -> phosphoenolpyruvate--protein phosphotransferase PtsI + ramR_E160D WP_000113609.1 + genbank_protein_accession -> ACH50230.1 + product_name TetR/AcrR family transcriptional regulator -> TetR/AcrR family transcriptional regulator RamR + ramR_G25A WP_000113609.1 + genbank_protein_accession -> ACH50230.1 + product_name TetR/AcrR family transcriptional regulator -> TetR/AcrR family transcriptional regulator RamR + ramR_M84I WP_000113609.1 + genbank_protein_accession -> ACH50230.1 + product_name TetR/AcrR family transcriptional regulator -> TetR/AcrR family transcriptional regulator RamR + ramR_R46P WP_000113609.1 + genbank_protein_accession -> ACH50230.1 + product_name TetR/AcrR family transcriptional regulator -> TetR/AcrR family transcriptional regulator RamR + ramR_T18P WP_000113609.1 + genbank_protein_accession -> ACH50230.1 + product_name TetR/AcrR family transcriptional regulator -> TetR/AcrR family transcriptional regulator RamR + ramR_T50P WP_000113609.1 + genbank_protein_accession -> ACH50230.1 + product_name TetR/AcrR family transcriptional regulator -> TetR/AcrR family transcriptional regulator RamR + ramR_Y59H WP_000113609.1 + genbank_protein_accession -> ACH50230.1 + product_name TetR/AcrR family transcriptional regulator -> TetR/AcrR family transcriptional regulator RamR + rpoB_H526Y WP_000263098.1 + genbank_protein_accession -> CSN35596.1 + product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB + rpoB_L533P WP_000263098.1 + genbank_protein_accession -> CSN35596.1 + product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB + rpoB_P564L WP_000263098.1 + genbank_protein_accession -> CSN35596.1 + product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB + rpoB_Q513L WP_000263098.1 + genbank_protein_accession -> CSN35596.1 + product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB + rpoB_Q513P WP_000263098.1 + genbank_protein_accession -> CSN35596.1 + product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB + rpoB_R529C WP_000263098.1 + genbank_protein_accession -> CSN35596.1 + product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB + rpoB_R529S WP_000263098.1 + genbank_protein_accession -> CSN35596.1 + product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB + rpoB_R687H WP_000263098.1 + genbank_protein_accession -> CSN35596.1 + product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB + rpoB_S531F WP_000263098.1 + genbank_protein_accession -> CSN35596.1 + product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB + rpoB_T563P WP_000263098.1 + genbank_protein_accession -> CSN35596.1 + product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB + rpoB_V146F WP_000263098.1 + genbank_protein_accession -> CSN35596.1 + product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB + rpsL_K43R WP_057042458.1 + genbank_protein_accession -> EAI0845362.1 + product_name 30S ribosomal protein S12 -> 30S ribosomal protein S12 RpsL + rpsL_K88E WP_057042458.1 + genbank_protein_accession -> EAI0845362.1 + product_name 30S ribosomal protein S12 -> 30S ribosomal protein S12 RpsL + rpsL_K88Q WP_057042458.1 + genbank_protein_accession -> EAI0845362.1 + product_name 30S ribosomal protein S12 -> 30S ribosomal protein S12 RpsL + rpsL_K88R WP_057042458.1 + genbank_protein_accession -> EAI0845362.1 + product_name 30S ribosomal protein S12 -> 30S ribosomal protein S12 RpsL + soxR_G121D WP_000412428.1 + genbank_protein_accession -> AAC77033.1 + soxR_G121D WP_000412686.1 + genbank_protein_accession -> CAD09250.1 + soxR_R20H WP_000412428.1 + genbank_protein_accession -> AAC77033.1 + soxR_R20H WP_000412686.1 + genbank_protein_accession -> CAD09250.1 + soxS_A12S WP_000019358.1 + genbank_protein_accession -> AAC77032.1 + soxS_E52K WP_000019483.1 + genbank_protein_accession -> AAL23089.1 + tufA_A376S WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_A376T WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_A376V WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_E379K WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_G317D WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_L121Q WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_Q125E WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_Q125K WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_Q125R WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_Q330H WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_R231C WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_R231V WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_R234F WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_R234S WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_R334C WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_T335A WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_Y161C WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_Y161D WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + tufA_Y161N WP_000031783.1 + genbank_protein_accession -> AAC76364.1 + uhpA_G97D WP_000633668.1 + genbank_protein_accession -> CDJ73205.1 + product_name DNA-binding response regulator -> DNA-binding response regulator UhpA + uhpT_E350Q WP_000879194.1 + genbank_protein_accession -> CDJ73208.1 + product_name hexose phosphate transporter -> hexose phosphate transporter UhpT + +- AMR HMM library Changes: + Total: Added 2 + Total: Prev. Release 618 + Total: Removed 0 + Total: This Release 620 + HMM Added: NF037973.1 myrA-NCBI + HMM Added: NF038003.1 blaPLA_ORN_TER-NCBI + HMM Modified: NF000389.2 blaPLA_ORN_TER-NCBI updated to NF000389.2 blaPFM-NCBI + HMM Modified: NF033560.1 myrA-NCBI updated to NF033560.1 metallo_SslE-NCBI + +- Protein family changes: + Total: Added 3 + Total: Prev. Release 1527 + Total: Removed 0 + Total: This Release 1530 + Family Added: - blaOKP-C + Family Added: - blaOKP-D + Family Added: NF037973.1 sslE + Family Changed: - blaPFM updated to NF038003.1 blaPFM + +--------------------------------------------------------------------- +Changes included in 2019-10-30.1 +--------------------------------------------------------------------- + +This update includes backward incompatible changes to the AMRFinderPlus +database format. It is compatible with AMRFinderPlus version 3.2 and above. +To use this database version please update to AMRFinderPlus version 3.2. See +https://github.com/ncbi/amr/wiki/Upgrading for how to upgrade and +https://github.com/evolarjun/amr/wiki/AMRFinderPlus-database for information +on the new database format. + +--organism / -O value Vibrio has been changed to Vibrio_cholerae because the +blacklisted genes are common only in Vibrio_cholerae. + +Two erronious proteins have been removed, several HMMs have been added, and +many new AMR alleles and "plus" genes. + +All HMM's have internal short names that have been changed to include a suffix +to indicate the source (e.g., NCBI, Resfams, TIGRFAMs). + +Class and subclass have been defined for some parent families where they were +not before. These will only be visible in AMRFinderPlus results if there was a +novel sequence classified by AMRFinder above the level of the gene included in +the Reference Gene Catalog. + +- Protein and point mutation changes: + Total in prev: 6271 + Total in release: 6443 + Removed: 2 + Added: 174 + Changed: 42 + Removed ltcA CAA23532.1 + Removed sdeA EEZ94110.1 + Added bmaE AAA23523.1 + Added papG-II AAA24293.1 + Added focG AAB20438.1 + Added cdtA AAF81760.1 + Added ibeA AAF98391.2 + Added iutA AAN45165.2 + Added sdeA AAS55383.1 + Added emrD ACN65732.1 + Added tcdR AJP10335.1 + Added tcdB AJP10336.1 + Added tcdE AJP10337.1 + Added tcdA AJP10339.1 + Added tcdC AJP10340.1 + Added sfaF ASJ31253.1 + Added emrD BAE77620.1 + Added papG-III CAA43558.1 + Added papA CAA43562.1 + Added papH CAA43563.1 + Added papC CAA43564.1 + Added papE CAA43568.1 + Added papG-I CAA43570.1 + Added afaC CAA54117.1 + Added afaC CAW30799.1 + Added cdtB CBE05858.1 + Added emrD EFF04178.1 + Added sfaF EIL44824.1 + Added papA ENA25238.1 + Added cvaC P22522.1 + Added mepA Q7A7N0.1 + Added blaOXA-856 WP_001021774.1 + Added blaOXA-847 WP_010793618.1 + Added blaOXA-851 WP_014603442.1 + Added tva(B) WP_014936356.1 + Added blaOXA-848 WP_019485147.1 + Added mcr-10.1 WP_023332837.1 + Added blaADC-212 WP_031975357.1 + Added blaADC-203 WP_032000414.1 + Added blaOXA-855 WP_032061328.1 + Added blaACT-74 WP_032652275.1 + Added blaOXA-846 WP_033989974.1 + Added blaOXA-850 WP_034006563.1 + Added blaADC-215 WP_039098799.1 + Added blaADC-216 WP_039211240.1 + Added blaADC-219 WP_039213353.1 + Added blaAQU-1 WP_042888870.1 + Added blaLEN-32 WP_043875313.1 + Added blaACT-75 WP_045347148.1 + Added blaCMY-137 WP_053390271.1 + Added blaADC-214 WP_060454527.1 + Added blaADC-217 WP_060470109.1 + Added blaLEN-42 WP_061154665.1 + Added fosA8 WP_063277905.1 + Added blaLEN-34 WP_072124806.1 + Added blaLEN-43 WP_074385924.1 + Added blaADC-218 WP_078216190.1 + Added blaADC-213 WP_078230092.1 + Added blaLEN-30 WP_080923375.1 + Added blaAXC-3 WP_081330264.1 + Added blaOXA-842 WP_087088911.1 + Added blaADC-220 WP_087876534.1 + Added blaLEN-55 WP_094917017.1 + Added blaAXC-2 WP_100505522.1 + Added blaLEN-41 WP_100675621.1 + Added blaLEN-12 WP_110196444.1 + Added blaOXA-854 WP_114158997.1 + Added blaADC-199 WP_114166683.1 + Added blaOXA-853 WP_114252036.1 + Added blaLEN-58 WP_117122976.1 + Added blaLEN-51 WP_123836928.1 + Added blaACT-76 WP_126817982.1 + Added blaADC-207 WP_130173437.1 + Added blaADC-194 WP_133972424.1 + Added blaOXA-822 WP_133973918.1 + Added blaPDC-319 WP_134254706.1 + Added blaLEN-39 WP_136026639.1 + Added blaLEN-40 WP_136049560.1 + Added blaLEN-38 WP_136086342.1 + Added blaPDC-322 WP_138403314.1 + Added blaOXA-894 WP_144376393.1 + Added blaADC-197 WP_150823452.1 + Added blaADC-198 WP_150823453.1 + Added blaADC-200 WP_150823454.1 + Added blaADC-201 WP_150823455.1 + Added blaADC-202 WP_150823456.1 + Added blaADC-204 WP_150823457.1 + Added blaADC-205 WP_150823458.1 + Added blaADC-206 WP_150823459.1 + Added blaADC-208 WP_150823460.1 + Added blaADC-209 WP_150823461.1 + Added blaADC-210 WP_150823462.1 + Added blaADC-211 WP_150823463.1 + Added blaAXC-4 WP_150823464.1 + Added blaAXC-5 WP_150823465.1 + Added blaCARB-51 WP_150823466.1 + Added blaCARB-52 WP_150823467.1 + Added blaEBR-3 WP_150823468.1 + Added blaIMP-65 WP_150823469.1 + Added blaOXA-838 WP_150823470.1 + Added blaOXA-839 WP_150823471.1 + Added blaOXA-840 WP_150823472.1 + Added blaOXA-841 WP_150823473.1 + Added blaOXA-843 WP_150823474.1 + Added blaOXA-844 WP_150823475.1 + Added blaOXA-845 WP_150823476.1 + Added blaOXA-849 WP_150823477.1 + Added blaPDC-318 WP_150823478.1 + Added blaPDC-320 WP_150823479.1 + Added blaPDC-321 WP_150823480.1 + Added blaPDC-323 WP_150823481.1 + Added blaPDC-324 WP_150823482.1 + Added blaPDC-325 WP_150823483.1 + Added blaPDC-326 WP_150823484.1 + Added blaPDC-327 WP_150823485.1 + Added blaPDC-328 WP_150823486.1 + Added blaPDC-329 WP_150823487.1 + Added blaPDC-330 WP_150823488.1 + Added blaPDC-331 WP_150823489.1 + Added blaPDC-332 WP_150823490.1 + Added blaPDC-384 WP_150823491.1 + Added blaPDC-385 WP_150823492.1 + Added blaPDC-386 WP_150823493.1 + Added blaPST-2 WP_150823494.1 + Added blaTEM-240 WP_150823495.1 + Added mcr-3.28 WP_150823496.1 + Added mcr-8.3 WP_150823497.1 + Added tva(A) WP_151874537.1 + Added blaACT-73 WP_152315464.1 + Added blaIMP-85 WP_152315465.1 + Added blaMIR-23 WP_152315466.1 + Added blaNDM-25 WP_152315467.1 + Added blaOXA-830 WP_152315468.1 + Added blaOXA-852 WP_152315469.1 + Added blaOXA-857 WP_152315470.1 + Added blaOXA-858 WP_152315471.1 + Added blaOXA-859 WP_152315472.1 + Added blaOXA-860 WP_152315473.1 + Added blaOXA-861 WP_152315474.1 + Added blaOXA-862 WP_152315475.1 + Added blaOXA-863 WP_152315476.1 + Added blaOXA-864 WP_152315477.1 + Added blaOXA-865 WP_152315478.1 + Added blaOXA-866 WP_152315479.1 + Added blaOXA-867 WP_152315480.1 + Added blaOXA-868 WP_152315481.1 + Added blaOXA-869 WP_152315482.1 + Added blaOXA-870 WP_152315483.1 + Added blaOXA-871 WP_152315484.1 + Added blaOXA-872 WP_152315485.1 + Added blaOXA-873 WP_152315486.1 + Added blaOXA-874 WP_152315487.1 + Added blaOXA-875 WP_152315488.1 + Added blaOXA-876 WP_152315489.1 + Added blaOXA-877 WP_152315490.1 + Added blaOXA-878 WP_152315491.1 + Added blaOXA-879 WP_152315492.1 + Added blaOXA-880 WP_152315493.1 + Added blaOXA-881 WP_152315494.1 + Added blaOXA-882 WP_152315495.1 + Added blaOXA-883 WP_152315496.1 + Added blaOXA-884 WP_152315497.1 + Added blaOXA-885 WP_152315498.1 + Added blaOXA-886 WP_152315499.1 + Added blaOXA-887 WP_152315500.1 + Added blaOXA-888 WP_152315501.1 + Added blaOXA-889 WP_152315502.1 + Added blaOXA-890 WP_152315503.1 + Added blaOXA-891 WP_152315504.1 + Added blaOXA-892 WP_152315505.1 + Added blaPDC-387 WP_152315506.1 + Added blaPDC-388 WP_152315507.1 + Added blaLEN-35 WP_152330887.1 + Added blaLEN-36 WP_152330888.1 + Added blaLEN-37 WP_152330889.1 + Added blaSHV-4 WP_152330890.1 + Changes: + arsB AAA21095.1 + blacklisted_taxa -> Escherichia + arsC AAB09628.1 + blacklisted_taxa -> Escherichia + ymgB AAC74250.1 + subclass ACID -> + subtype BIOCIDE -> ACID + emrD3 ABQ18953.1 + blacklisted_taxa Vibrio -> Vibrio_cholerae + arsB BAA24823.1 + blacklisted_taxa -> Escherichia + fieF BAB89353.1 + blacklisted_taxa -> Klebsiella + aac(6')-I WP_002289795.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_002293569.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_002293989.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_002328174.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_002339746.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_002373947.1 + gene_family aac(6') -> aac(6')-I + aac(6')-Iih WP_005880220.1 + gene_family aac(6') -> aac(6')-I + aac(6')-Ii WP_008265821.1 + gene_family aac(6') -> aac(6')-I + aac(6')-Iid WP_010720790.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_010723742.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_010727362.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_010728104.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_010736157.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_010737153.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_010750427.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_010752789.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_010768325.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_016172918.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_016177698.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_016628216.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_019722502.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_023519215.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_024635824.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_034688908.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_034700626.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_034860925.1 + gene_family aac(6') -> aac(6')-I + blaOXA-252 WP_037428895.1 + curated_refseq_start Yes -> No + genbank_cds_start 842113 -> 2724286 + genbank_cds_stop 842910 -> 2725083 + genbank_nucleotide_accession JTLE01000094.1 -> CP022089.2 + genbank_protein_accession -> ASF15667.1 + genbank_strand_orientation + -> - + refseq_nucleotide_accession NG_050608.1 -> NG_066509.1 + aac(6')-I WP_048603867.1 + gene_family aac(6') -> aac(6')-I + aac(6')-I WP_053766315.1 + gene_family aac(6') -> aac(6')-I + blaOXA-539 WP_071593233.1 + product_name OXA-2 family class D extended-spectrum beta-lactamase OXA-539 -> OXA-2 family inhibitor-resistant class D extended-spectrum beta-lactamase OXA-539 + subclass BETA-LACTAM -> CEPHALOSPORIN + lnu(F) WP_071846285.1 + allele linH2 -> + aac(6')-I WP_071846353.1 + gene_family aac(6') -> aac(6')-I + blaOXA-576 WP_087696200.1 + curated_refseq_start Yes -> No + genbank_cds_start 843910 -> 1 + genbank_cds_stop 844656 -> 747 + genbank_nucleotide_accession NFPA01000015.1 -> MH085550.1 + genbank_protein_accession -> AWD39715.1 + refseq_nucleotide_accession NG_057458.1 -> NG_066510.1 + blaAQU WP_099156042.1 + allele blaAQU-1 -> + product_name class C beta-lactamase AQU-1 -> AQU family class C beta-lactamase + blaKPC-40 WP_115470049.1 + product_name carbapenem-hydrolyzing class A beta-lactamase KPC-40 -> inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-40 + blaOXA-681 WP_122630881.1 + product_name OXA-2 family class D beta-lactamase OXA-681 -> OXA-2 family inhibitor-resistant class D extended-spectrum beta-lactamase OXA-681 + subclass BETA-LACTAM -> CEPHALOSPORIN +- AMR HMM library Changes: + Total: Added 10 + Total: Prev. Release 608 + Total: Removed 0 + Total: This Release 618 + HMM Added: 154989_fosA-NCBI + HMM Added: NF000252.1 MsrSA-NCBI + HMM Added: NF000282.2 RPH_KJ151292.1-NCBI + HMM Added: NF000315.1 amicyc_ac_ApmA-NCBI + HMM Added: NF028537.1 QacCGHJ-NCBI + HMM Added: NF033086.2 penta_rpt_QnrA-NCBI + HMM Added: NF033134.0 cmlB1_MFS-NCBI + HMM Added: NF033643.1 FOX-MOX-NCBI + HMM Added: NF033651.1 dipept_VanX-NCBI + HMM Added: NF033653.1 blaOXA-274_like-NCBI + HMM Modified: NF000004.1 vanH-D updated to NF000004.1 vanH-Sc-NCBI + HMM Modified: NF000005.4 ble_BLMT updated to NF000005.4 ble_MBL-NCBI + HMM Modified: NF000006.2 trim_DfrA26 updated to NF000006.2 trim_DfrA3-NCBI + HMM Modified: NF000007.1 16S_rRNA_Rmt_D updated to NF000007.1 16S_rRNA_Rmt_E-NCBI + HMM Modified: NF000008.1 trim_DfrA1_rpt updated to NF000008.1 trim_DfrA20-NCBI + HMM Modified: NF000009.1 tet_MFS_Tcr3 updated to NF000009.1 tet_MFS_V-NCBI + HMM Modified: NF000010.1 AAC_2p_Ib updated to NF000010.1 AAC_2p_Ic-NCBI + HMM Modified: NF000011.2 APH_6_Ic updated to NF000011.2 APH_6_Ic_gen-NCBI + HMM Modified: NF000012.1 trim_DfrI updated to NF000012.1 vanH-Ac1-NCBI + HMM Modified: NF000013.1 tet_NaH_anti_35 updated to NF000013.1 tet_destruct-NCBI + HMM Modified: NF000014.1 tet_prtrans_34 updated to NF000014.1 tet_redox_37-NCBI + HMM Modified: NF000015.3 APH_2pp_IIa updated to NF000015.3 APH_2pp_I_a_f_h-NCBI + HMM Modified: NF000016.1 AAC_6p_Im updated to NF000016.1 AAC_6p_Ip-NCBI + HMM Modified: NF000017.1 linco_LnuD updated to NF000017.1 linco_LnuE-NCBI + HMM Modified: NF000018.2 trim_DfrA10 updated to NF000018.2 trim_DfrA12-NCBI + HMM Modified: NF000019.2 trim_DfrA3 updated to NF000019.2 trim_DfrA35-NCBI + HMM Modified: NF000020.1 stregram_VatE updated to NF000020.1 stregram_VatF-NCBI + HMM Modified: NF000021.4 AAC_6p_Serra updated to NF000021.4 AAC_6p_Steno-NCBI + HMM Modified: NF000022.1 stregra_B_VgbA updated to NF000022.1 stregra_B_VgbB-NCBI + HMM Modified: NF000023.1 qac_SMR_C updated to NF000023.1 qac_SMR_G-NCBI + HMM Modified: NF000024.1 ErmS updated to NF000024.1 ErmV-NCBI + HMM Modified: NF000025.1 MFS_efflux_tcmA updated to NF000025.1 MOX_CMY1_fam-NCBI + HMM Modified: NF000026.1 154989_fosA updated to NF000026.1 156720500_bleO-NCBI + HMM Modified: NF000027.1 156720500_bleO updated to NF000027.1 1567214_ble-NCBI + HMM Modified: NF000028.1 1567214_ble updated to NF000028.1 16S_rRNA_NpmA-NCBI + HMM Modified: NF000029.2 APH_9_Ib updated to NF000029.2 BlaA_Yent-NCBI + HMM Modified: NF000030.1 16S_rRNA_NpmA updated to NF000030.1 16S_rRNA_Rmt_B-NCBI + HMM Modified: NF000032.1 D_ala_D_ser_VanL updated to NF000032.1 D_ala_D_ser_VanN-NCBI + HMM Modified: NF000033.1 vanT-L-mem updated to NF000033.1 vanW-B-NCBI + HMM Modified: NF000034.1 AAC_2p_Ic updated to NF000034.1 AAC_2p_Id-NCBI + HMM Modified: NF000035.1 nosihep_NshR updated to NF000035.1 penta_rpt_Qnr-NCBI + HMM Modified: NF000036.1 D_ala_D_ser_VanE updated to NF000036.1 D_ala_D_ser_VanG-NCBI + HMM Modified: NF000037.1 RND_perm_OqxB updated to NF000037.1 RND_permease_1-NCBI + HMM Modified: NF000039.1 trim_DfrA18 updated to NF000039.1 trim_DfrA19-NCBI + HMM Modified: NF000041.1 trim_DfrA19 updated to NF000041.1 trim_DfrA1_like-NCBI + HMM Modified: NF000042.1 AAC_2p_Id updated to NF000042.1 AAC_2p_Ie-NCBI + HMM Modified: NF000043.1 tet_MFS_P_a updated to NF000043.1 tet_MFS_Tcr3-NCBI + HMM Modified: NF000044.2 APH_2pp_IIIa updated to NF000044.2 APH_2pp_IIa-NCBI + HMM Modified: NF000047.1 ErmV updated to NF000047.1 EspJ_gen-NCBI + HMM Modified: NF000048.1 AAC_6p_A40 updated to NF000048.1 AAC_6p_A48-NCBI + HMM Modified: NF000049.1 tet_MFS_40 updated to NF000049.1 tet_MFS_42-NCBI + HMM Modified: NF000050.2 AAC_6p_A29 updated to NF000050.2 AAC_6p_A30-NCBI + HMM Modified: NF000051.1 macrolide_MefB updated to NF000051.1 macrolide_MefC-NCBI + HMM Modified: NF000052.4 APH_9_Ia updated to NF000052.4 APH_9_Ib-NCBI + HMM Modified: NF000053.2 trim_DfrA12 updated to NF000053.2 trim_DfrA13_A21-NCBI + HMM Modified: NF000054.1 AAC_2p_Ie updated to NF000054.1 AAC_3-NCBI + HMM Modified: NF000055.3 trim_DfrA13_A21 updated to NF000055.3 trim_DfrA18-NCBI + HMM Modified: NF000056.3 penta_rpt_QnrS updated to NF000056.3 penta_rpt_QnrVC-NCBI + HMM Modified: NF000059.1 tet_redox_37 updated to NF000059.1 toxin_EAST1-NCBI + HMM Modified: NF000061.1 linco_LnuP updated to NF000061.1 lyase_MerB-NCBI + HMM Modified: NF000062.1 ANT_6_str updated to NF000062.1 ANT_9-NCBI + HMM Modified: NF000063.1 Fos_BSH_Sepi updated to NF000063.1 Fos_GSH-NCBI + HMM Modified: NF000064.3 ANT_2pp_Ia updated to NF000064.3 ANT_3pp_AadA1-NCBI + HMM Modified: NF000065.1 trim_DfrA3b updated to NF000065.1 trim_DfrA8-NCBI + HMM Modified: NF000066.1 rifampin_ARR_Sa updated to NF000066.1 sat2-NCBI + HMM Modified: NF000067.2 SMR_qac_FL updated to NF000067.2 SMR_qac_G2-NCBI + HMM Modified: NF000069.1 16S_rRNA_Rmt_E updated to NF000069.1 16S_rRNA_Rmt_F-NCBI + HMM Modified: NF000071.4 penta_rpt_QnrA updated to NF000071.4 penta_rpt_QnrAS-NCBI + HMM Modified: NF000072.1 MFS_efflux_PexA updated to NF000072.1 MFS_efflux_tcmA-NCBI + HMM Modified: NF000074.1 299782349_fosC updated to NF000074.1 299782351_fosA-NCBI + HMM Modified: NF000075.1 299782351_fosA updated to NF000075.1 354827590_fosA-NCBI + HMM Modified: NF000076.3 APH_2pp_Ie_IVa updated to NF000076.3 APH_2pp_If_Ih-NCBI + HMM Modified: NF000077.1 Erm42 updated to NF000077.1 Erm43-NCBI + HMM Modified: NF000079.1 ANT_4p_Ib updated to NF000079.1 ANT_6-NCBI + HMM Modified: NF000084.1 amicyc_ac_ApmA updated to NF000084.1 arsB_Sta_pI258-NCBI + HMM Modified: NF000085.1 Fos_BSH_Saur updated to NF000085.1 Fos_BSH_Sepi-NCBI + HMM Modified: NF000086.1 vanY_far updated to NF000086.1 vanY_of_D-NCBI + HMM Modified: NF000087.1 ErmO updated to NF000087.1 ErmS-NCBI + HMM Modified: NF000088.1 viomycin_Vph updated to NF000088.1 zbmA-NCBI + HMM Modified: NF000089.1 qac_MFS_AB updated to NF000089.1 qac_SMR_C-NCBI + HMM Modified: NF000090.1 trans_reg_VanU updated to NF000090.1 transloc_TIR-NCBI + HMM Modified: NF000091.3 D_ala_D_ser_VanG updated to NF000091.3 D_ala_D_ser_VanL-NCBI + HMM Modified: NF000092.1 D_ala_D_lac_Ao2 updated to NF000092.1 D_ala_D_lac_Sc-NCBI + HMM Modified: NF000093.1 D_ala_D_ser_VanN updated to NF000093.1 EreA-NCBI + HMM Modified: NF000094.1 354827590_fosA updated to NF000094.1 47473_otr-NCBI + HMM Modified: NF000095.1 tet_MFS_OtrB updated to NF000095.1 tet_MFS_P_a-NCBI + HMM Modified: NF000096.1 stregra_B_VgbB updated to NF000096.1 stregram_VatA-NCBI + HMM Modified: NF000097.1 stregram_VatC updated to NF000097.1 stregram_VatD-NCBI + HMM Modified: NF000098.1 Fos_BSH_Bcer updated to NF000098.1 Fos_BSH_Saur-NCBI + HMM Modified: NF000100.2 AAC_2p_IIa updated to NF000100.2 AAC_2p_IIb-NCBI + HMM Modified: NF000101.1 stregram_VatA updated to NF000101.1 stregram_VatC-NCBI + HMM Modified: NF000103.1 tet_ABC_AB_B updated to NF000103.1 tet_MFS_38-NCBI + HMM Modified: NF000107.2 APH_4_Ia updated to NF000107.2 APH_6-NCBI + HMM Modified: NF000108.1 AAC_2p_Ia updated to NF000108.1 AAC_2p_Ib-NCBI + HMM Modified: NF000109.2 trim_DfrA9 updated to NF000109.2 trim_DfrB-NCBI + HMM Modified: NF000110.2 AAC_6p_If updated to NF000110.2 AAC_6p_Il-NCBI + HMM Modified: NF000111.1 stregram_VatD updated to NF000111.1 stregram_VatE-NCBI + HMM Modified: NF000112.1 vanH-Amyco updated to NF000112.1 vanH-D-NCBI + HMM Modified: NF000113.1 16S_rRNA_Rmt_F updated to NF000113.1 16S_rRNA_Rmt_G-NCBI + HMM Modified: NF000114.1 16S_rRNA_Rmt_G updated to NF000114.1 16S_rRNA_Rmt_H-NCBI + HMM Modified: NF000115.2 AAC_6p_Iad updated to NF000115.2 AAC_6p_Iak-NCBI + HMM Modified: NF000116.1 16S_rRNA_Rmt_H updated to NF000116.1 16S_rRNA_Rmt_gen-NCBI + HMM Modified: NF000118.3 AAC_6p_A31 updated to NF000118.3 AAC_6p_A34-NCBI + HMM Modified: NF000119.1 linco_LnuF updated to NF000119.1 linco_LnuG-NCBI + HMM Modified: NF000120.3 47473_otr updated to NF000120.3 485965_fosC-NCBI + HMM Modified: NF000122.1 485965_fosC updated to NF000122.1 491618165_fosA-NCBI + HMM Modified: NF000123.2 AAC_6p_A34 updated to NF000123.2 AAC_6p_A37-NCBI + HMM Modified: NF000124.1 491618165_fosA updated to NF000124.1 498180014_fosA-NCBI + HMM Modified: NF000125.1 498180014_fosA updated to NF000125.1 AAC_2p_IIa-NCBI + HMM Modified: NF000126.2 trim_DfrA8 updated to NF000126.2 trim_DfrA9-NCBI + HMM Modified: NF000127.2 trim_DfrA20 updated to NF000127.2 trim_DfrA23-NCBI + HMM Modified: NF000128.1 vanH-Sc updated to NF000128.1 vanH_Agroup-NCBI + HMM Modified: NF000129.1 D_ala_D_lac_Sc updated to NF000129.1 D_ala_D_lac_VanA-NCBI + HMM Modified: NF000131.1 MATE_multi_MepA updated to NF000131.1 MATE_multi_NorM-NCBI + HMM Modified: NF000132.2 APH_2pp_Ig updated to NF000132.2 APH_3p-NCBI + HMM Modified: NF000133.1 Erm32 updated to NF000133.1 Erm37-NCBI + HMM Modified: NF000134.2 trim_DfrA23 updated to NF000134.2 trim_DfrA24-NCBI + HMM Modified: NF000135.2 AAC_6p_IIc updated to NF000135.2 AAC_6p_Ia_fam-NCBI + HMM Modified: NF000137.2 APH_7pp_Ia updated to NF000137.2 APH_9_Ia-NCBI + HMM Modified: NF000138.1 AAC_6p_Iz updated to NF000138.1 AAC_6p_Serra-NCBI + HMM Modified: NF000139.2 penta_rpt_QnrD updated to NF000139.2 penta_rpt_QnrE-NCBI + HMM Modified: NF000141.1 linco_LnuC updated to NF000141.1 linco_LnuD-NCBI + HMM Modified: NF000142.1 vanZ-Pt updated to NF000142.1 viomycin_Vph-NCBI + HMM Modified: NF000143.1 trim_DfrG updated to NF000143.1 trim_DfrI-NCBI + HMM Modified: NF000144.1 D_ala_D_lac_VanF updated to NF000144.1 D_ala_D_lac_VanI-NCBI + HMM Modified: NF000145.1 vanZ-F updated to NF000145.1 vanZ-Pt-NCBI + HMM Modified: NF000146.2 trim_DfrA24 updated to NF000146.2 trim_DfrA26-NCBI + HMM Modified: NF000147.1 stregram_VatF updated to NF000147.1 stregram_VatH-NCBI + HMM Modified: NF000148.1 SMR_qac_pB8 updated to NF000148.1 Shiga_Stx1A-NCBI + HMM Modified: NF000149.1 vanXY_G updated to NF000149.1 vanY_AFMPt-NCBI + HMM Modified: NF000150.1 16S_rRNA_Rmt_C updated to NF000150.1 16S_rRNA_Rmt_D-NCBI + HMM Modified: NF000151.1 vanH-Ac1 updated to NF000151.1 vanH-Amyco-NCBI + HMM Modified: NF000152.2 AAC_6p_A37 updated to NF000152.2 AAC_6p_A40-NCBI + HMM Modified: NF000153.1 linco_LnuAN2 updated to NF000153.1 linco_LnuB-NCBI + HMM Modified: NF000154.1 macrolide_MefEN2 updated to NF000154.1 macrolide_MphA-NCBI + HMM Modified: NF000155.1 trim_DfrC updated to NF000155.1 trim_DfrD-NCBI + HMM Modified: NF000157.1 fusid_est_FusH updated to NF000157.1 glycotrans_Rgt-NCBI + HMM Modified: NF000158.2 AAC_6p_Il updated to NF000158.2 AAC_6p_Im-NCBI + HMM Modified: NF000159.1 trim_DfrD updated to NF000159.1 trim_DfrDGK-NCBI + HMM Modified: NF000165.3 AAC_6p_Entco updated to NF000165.3 AAC_6p_IIc-NCBI + HMM Modified: NF000166.1 ABCF_CarA updated to NF000166.1 ABCF_Lsa_all-NCBI + HMM Modified: NF000167.1 ABCF_Lsa_all updated to NF000167.1 ABCF_Msr_all-NCBI + HMM Modified: NF000168.1 ABCF_Msr_all updated to NF000168.1 ABCF_OptrA-NCBI + HMM Modified: NF000169.1 ABCF_Sal updated to NF000169.1 ABCF_Vga_all-NCBI + HMM Modified: NF000170.1 ABCF_Vga_all updated to NF000170.1 ABCF_producer-NCBI + HMM Modified: NF000171.1 ABCF_producer updated to NF000171.1 ANT_2pp_Ia-NCBI + HMM Modified: NF000181.1 ANT_4p_Ia updated to NF000181.1 ANT_4p_Ib-NCBI + HMM Modified: NF000185.2 BlaEC updated to NF000185.2 BlaI_of_MRSA-NCBI + HMM Modified: NF000186.1 BlaI_of_MRSA updated to NF000186.1 BlaMIR-NCBI + HMM Modified: NF000187.3 BlaMIR updated to NF000187.3 BlmB-NCBI + HMM Modified: NF000188.2 CARB updated to NF000188.2 CAR_gen_B3-NCBI + HMM Modified: NF000191.1 CMY2 updated to NF000191.1 CfrAB-NCBI + HMM Modified: NF000206.1 D_ala_D_lac updated to NF000206.1 D_ala_D_lac_Ao2-NCBI + HMM Modified: NF000207.3 D_ala_D_ser updated to NF000207.3 D_ala_D_ser_VanC-NCBI + HMM Modified: NF000208.1 EreA updated to NF000208.1 EreB-NCBI + HMM Modified: NF000209.1 EreB updated to NF000209.1 EreD-NCBI + HMM Modified: NF000216.2 blaFEZ updated to NF000216.2 blaFIM-NCBI + HMM Modified: NF000218.1 FexA updated to NF000218.1 FloR-NCBI + HMM Modified: NF000219.1 FloR updated to NF000219.1 FosA-NCBI + HMM Modified: NF000221.4 FosA updated to NF000221.4 FosF-NCBI + HMM Modified: NF000222.1 FosX updated to NF000222.1 Fos_BSH-NCBI + HMM Modified: NF000224.3 AAC_6p_Acine updated to NF000224.3 AAC_6p_Entco-NCBI + HMM Modified: NF000225.3 AAC_6p_Strep updated to NF000225.3 AAC_6p_Yersi-NCBI + HMM Modified: NF000232.1 L2 updated to NF000232.1 LEN-NCBI + HMM Modified: NF000233.2 LEN updated to NF000233.2 MATE_multi_MepA-NCBI + HMM Modified: NF000235.3 linco_LnuB updated to NF000235.3 linco_LnuC-NCBI + HMM Modified: NF000236.1 linco_LnuA updated to NF000236.1 linco_LnuAN2-NCBI + HMM Modified: NF000237.1 MECA_PBP2A updated to NF000237.1 MECA_pure-NCBI + HMM Modified: NF000239.3 MOX_CMY1_fam updated to NF000239.3 MPH_3-NCBI + HMM Modified: NF000240.1 macrolide_MphC updated to NF000240.1 macrolide_MphE-NCBI + HMM Modified: NF000241.1 MPH_3 updated to NF000241.1 MecI_of_mecA-NCBI + HMM Modified: NF000242.1 macrolide_MphB updated to NF000242.1 macrolide_MphC-NCBI + HMM Modified: NF000243.1 MecI_of_mecA updated to NF000243.1 MecI_of_mecC-NCBI + HMM Modified: NF000244.1 MecI_of_mecC updated to NF000244.1 MerA-TIGRFAMs + HMM Modified: NF000245.1 macrolide_MefA updated to NF000245.1 macrolide_MefB-NCBI + HMM Modified: NF000246.1 macrolide_MefC updated to NF000246.1 macrolide_MefEN2-NCBI + HMM Modified: NF000249.1 MexE updated to NF000249.1 MexX-Resfams + HMM Modified: NF000254.1 macrolide_MphA updated to NF000254.1 macrolide_MphB-NCBI + HMM Modified: NF000255.1 macrolide_MphF updated to NF000255.1 merT_RC607-NCBI + HMM Modified: NF000256.1 MsrSA updated to NF000256.1 MupA-NCBI + HMM Modified: NF000257.1 MupA updated to NF000257.1 MupB-NCBI + HMM Modified: NF000258.1 MupB updated to NF000258.1 NimABCDEF-NCBI + HMM Modified: NF000259.2 blaNDM updated to NF000259.2 blaOCH-NCBI + HMM Modified: NF000261.1 NimABCDEF updated to NF000261.1 NimIJ-NCBI + HMM Modified: NF000262.1 NimIJ updated to NF000262.1 NshR_TsnR-NCBI + HMM Modified: NF000263.1 MATE_multi_NorM updated to NF000263.1 MECA1_pure-NCBI + HMM Modified: NF000264.2 blaOCH updated to NF000264.2 blaOXA-10_like-NCBI + HMM Modified: NF000265.2 OKP updated to NF000265.2 OqxA_adapt_sub-NCBI + HMM Modified: NF000266.2 blaOXA-23_like updated to NF000266.2 blaOXA-24_like-NCBI + HMM Modified: NF000267.2 blaOXA-2_like updated to NF000267.2 blaOXA-364_like-NCBI + HMM Modified: NF000268.2 blaOXA-51_like updated to NF000268.2 blaOXA-55_like-NCBI + HMM Modified: NF000269.2 blaOXA-213_like updated to NF000269.2 blaOXA-214_like-NCBI + HMM Modified: NF000270.1 bla_class_D_alt updated to NF000270.1 bla_class_D_main-NCBI + HMM Modified: NF000271.2 blaOXY updated to NF000271.2 blaP-NCBI + HMM Modified: NF000272.1 OqxA_adapt_sub updated to NF000272.1 PRK10026.1-PRKfam + HMM Modified: NF000275.2 blaPLA_ORN_TER updated to NF000275.2 blaPME-NCBI + HMM Modified: NF000276.2 SMR_qac_E updated to NF000276.2 SMR_qac_FL-NCBI + HMM Modified: NF000277.1 qac_SMR_G updated to NF000277.1 qac_SMR_H-NCBI + HMM Modified: NF000278.1 SMR_qac_G2 updated to NF000278.1 SMR_qac_K-NCBI + HMM Modified: NF000279.1 qac_SMR_H updated to NF000279.1 qac_SMR_J-NCBI + HMM Modified: NF000280.1 SMR_efflux_smr updated to NF000280.1 SMR_qac_E-NCBI + HMM Modified: NF000283.1 RPH_KJ151292.1 updated to NF000283.1 RTG-NCBI + HMM Modified: NF000284.1 RTG updated to NF000284.1 SHV-NCBI + HMM Modified: NF000285.3 SHV updated to NF000285.3 SHV_LEN_OKP-NCBI + HMM Modified: NF000287.1 SMB1_fam updated to NF000287.1 SMR_efflux_smr-NCBI + HMM Modified: NF000294.1 Sul1 updated to NF000294.1 Sul2-NCBI + HMM Modified: NF000295.1 Sul2 updated to NF000295.1 Sul3-NCBI + HMM Modified: NF000296.1 Sul3 updated to NF000296.1 Sul4-NCBI + HMM Modified: NF000298.2 blaTLA updated to NF000298.2 blaTMB-NCBI + HMM Modified: NF000311.1 Vat_ABCDEFH updated to NF000311.1 aadE-Cc-NCBI + HMM Modified: NF000312.1 ANT_6_aadK updated to NF000312.1 ANT_6_aadS-NCBI + HMM Modified: NF000318.1 rifampin_ARR_Ms updated to NF000318.1 rifampin_ARR_Sa-NCBI + HMM Modified: NF000320.2 betalact_A_Burk_PenA updated to NF000320.2 betalact_A_Burk_PenI-NCBI + HMM Modified: NF000321.2 betalact_A_Burk_PenI updated to NF000321.2 bla-A_Chryseo-NCBI + HMM Modified: NF000322.2 blaCcrA updated to NF000322.2 blaDHA-NCBI + HMM Modified: NF000323.2 blaFONA updated to NF000323.2 blaFOX-NCBI + HMM Modified: NF000324.2 blaLUT updated to NF000324.2 blaMCA-NCBI + HMM Modified: NF000326.1 blaR1_generic updated to NF000326.1 blaRCP-NCBI + HMM Modified: NF000327.2 blaSCO updated to NF000327.2 blaSED-NCBI + HMM Modified: NF000328.2 blaSED updated to NF000328.2 blaSFH-NCBI + HMM Modified: NF000329.2 bla_B2_CphA updated to NF000329.2 bla_Bc_2-NCBI + HMM Modified: NF000330.1 trim_DfrA1_like updated to NF000330.1 trim_DfrA1_rpt-NCBI + HMM Modified: NF000331.1 trim_DfrB updated to NF000331.1 trim_DfrC-NCBI + HMM Modified: NF000332.1 trim_DfrDGK updated to NF000332.1 trim_DfrE-NCBI + HMM Modified: NF000333.1 trim_DfrF updated to NF000333.1 trim_DfrG-NCBI + HMM Modified: NF000336.1 emrE updated to NF000336.1 erm_38_23S_MT-NCBI + HMM Modified: NF000337.1 erm_SHROVE updated to NF000337.1 fomA_AB016934.1.gene6-NCBI + HMM Modified: NF000338.1 fomA_AB016934.1.gene6 updated to NF000338.1 fos-Crono-NCBI + HMM Modified: NF000339.2 fos-Crono updated to NF000339.2 fosA7-NCBI + HMM Modified: NF000340.1 fusB updated to NF000340.1 fusC-NCBI + HMM Modified: NF000341.1 fusC updated to NF000341.1 fusD-NCBI + HMM Modified: NF000343.1 rif_mono_Iri updated to NF000343.1 rif_monoox-NCBI + HMM Modified: NF000354.1 glycotrans_Rgt updated to NF000354.1 intimin_all-NCBI + HMM Modified: NF000355.3 ribo_prot_ABC_F updated to NF000355.3 rif_mono_Iri-NCBI + HMM Modified: NF000358.1 sat2 updated to NF000358.1 sat3-NCBI + HMM Modified: NF000359.1 sat3 updated to NF000359.1 sat4-NCBI + HMM Modified: NF000360.1 sat4 updated to NF000360.1 self_FomB_kinase-NCBI + HMM Modified: NF000361.1 self_FomB_kinase updated to NF000361.1 self_GT_OleI-NCBI + HMM Modified: NF000362.1 self_GT_OleI updated to NF000362.1 self_KamB-NCBI + HMM Modified: NF000363.1 self_KamB updated to NF000363.1 sensor_BlaR1-NCBI + HMM Modified: NF000371.1 vanH_Agroup updated to NF000371.1 vanH_gen-NCBI + HMM Modified: NF000372.1 D_ala_D_lac_VanI updated to NF000372.1 D_ala_D_lac_VanM-NCBI + HMM Modified: NF000373.1 vanJ updated to NF000373.1 vanR-A-NCBI + HMM Modified: NF000374.1 D_ala_D_lac_VanO updated to NF000374.1 D_ala_D_ser-NCBI + HMM Modified: NF000380.1 vanXY updated to NF000380.1 vanXY_G-NCBI + HMM Modified: NF000383.2 blaLAP updated to NF000383.2 blaLHK-NCBI + HMM Modified: NF000384.1 QacCGHJ updated to NF000384.1 RND_adapt_MexA-NCBI + HMM Modified: NF000385.4 blaACT updated to NF000385.4 blaADC-NCBI + HMM Modified: NF000386.2 blaOXA-10_like updated to NF000386.2 blaOXA-114_like-NCBI + HMM Modified: NF000387.2 blaOXA-48_like updated to NF000387.2 blaOXA-493_like-NCBI + HMM Modified: NF000388.2 blaOXA-1_like updated to NF000388.2 blaOXA-211_like-NCBI + HMM Modified: NF000389.2 blaPER updated to NF000389.2 blaPLA_ORN_TER-NCBI + HMM Modified: NF000390.2 blaVEB updated to NF000390.2 blaVIM-NCBI + HMM Modified: NF000395.3 blaOXA-60_like updated to NF000395.3 blaOXA-61_like-NCBI + HMM Modified: NF000396.2 blaGIM updated to NF000396.2 blaGOB-NCBI + HMM Modified: NF000397.2 blaACC updated to NF000397.2 blaACI-NCBI + HMM Modified: NF000398.2 blaBEL updated to NF000398.2 blaBES-NCBI + HMM Modified: NF000399.2 blaFOX updated to NF000399.2 blaFRI-NCBI + HMM Modified: NF000400.2 blaIMI updated to NF000400.2 blaIMP-NCBI + HMM Modified: NF000401.1 vanR-A updated to NF000401.1 vanR-B-NCBI + HMM Modified: NF000402.1 vanR-B updated to NF000402.1 vanR-C-NCBI + HMM Modified: NF000403.1 vanR-C updated to NF000403.1 vanR-D-NCBI + HMM Modified: NF000404.1 vanR-D updated to NF000404.1 vanR-O-NCBI + HMM Modified: NF000405.1 HARLDQ_not_B3 updated to NF000405.1 HK_VanS_ACDEFG-NCBI + HMM Modified: NF000406.1 MECB_PBP updated to NF000406.1 MECC_PBP-NCBI + HMM Modified: NF000407.1 MECC_PBP updated to NF000407.1 MECD_PBP-NCBI + HMM Modified: NF000408.1 MECA2_pure updated to NF000408.1 MECA_PBP2A-NCBI + HMM Modified: NF000409.1 MECA_pure updated to NF000409.1 MECB_PBP-NCBI + HMM Modified: NF000410.1 MECA1_pure updated to NF000410.1 MECA2_pure-NCBI + HMM Modified: NF000411.1 Erm45 updated to NF000411.1 ErmO-NCBI + HMM Modified: NF000412.1 Erm43 updated to NF000412.1 Erm45-NCBI + HMM Modified: NF000413.2 blaBKC updated to NF000413.2 blaBKC_GPC-NCBI + HMM Modified: NF000414.2 blaPME updated to NF000414.2 blaPOM-NCBI + HMM Modified: NF000415.2 blaOXA-372_like updated to NF000415.2 blaOXA-46_like-NCBI + HMM Modified: NF000417.2 blaOXA-211_like updated to NF000417.2 blaOXA-213_like-NCBI + HMM Modified: NF000418.2 blaOXA-214_like updated to NF000418.2 blaOXA-229_like-NCBI + HMM Modified: NF000419.2 blaCMH updated to NF000419.2 blaCPS-NCBI + HMM Modified: NF000420.1 penta_rpt_QnrB updated to NF000420.1 penta_rpt_QnrC-NCBI + HMM Modified: NF000421.1 penta_rpt_QnrVC updated to NF000421.1 phenyl_MerG-NCBI + HMM Modified: NF000422.6 blaPDC updated to NF000422.6 blaPDC_var-NCBI + HMM Modified: NF000423.2 blaSRT updated to NF000423.2 blaTEM-NCBI + HMM Modified: NF000424.3 CfrAB updated to NF000424.3 D_ala_D_lac-NCBI + HMM Modified: NF000425.2 blaADC updated to NF000425.2 blaAFM-NCBI + HMM Modified: NF000426.2 blaSIM updated to NF000426.2 blaSME-NCBI + HMM Modified: NF000427.2 blaCAU updated to NF000427.2 blaCBP-NCBI + HMM Modified: NF000428.4 blaFRI updated to NF000428.4 blaFTU-NCBI + HMM Modified: NF000429.2 blaOXA-63_like updated to NF000429.2 blaOXA-727_like-NCBI + HMM Modified: NF000430.2 blaOXA-62_like updated to NF000430.2 blaOXA-63_like-NCBI + HMM Modified: NF000431.1 AAC_6p_Ian updated to NF000431.1 AAC_6p_Ib-NCBI + HMM Modified: NF000432.2 blaOXA-50_like updated to NF000432.2 blaOXA-51_like-NCBI + HMM Modified: NF000434.2 blaOXA-24_like updated to NF000434.2 blaOXA-266_fam-NCBI + HMM Modified: NF000435.2 blaOXA-61_like updated to NF000435.2 blaOXA-62_like-NCBI + HMM Modified: NF000436.2 blaOXA-134_like updated to NF000436.2 blaOXA-143_like-NCBI + HMM Modified: NF000437.2 blaFIM updated to NF000437.2 blaFONA-NCBI + HMM Modified: NF000438.2 blaPOM updated to NF000438.2 blaPST-NCBI + HMM Modified: NF000439.2 blaAIM updated to NF000439.2 blaALI-NCBI + HMM Modified: NF000440.2 blaTHIN updated to NF000440.2 blaTLA-NCBI + HMM Modified: NF000441.2 blaMUS updated to NF000441.2 blaNDM-NCBI + HMM Modified: NF000442.2 blaTUS updated to NF000442.2 blaVCC-NCBI + HMM Modified: NF000443.2 blaTMB updated to NF000443.2 blaTTU-NCBI + HMM Modified: NF000444.2 blaEBR updated to NF000444.2 blaESP-1_fam-NCBI + HMM Modified: NF000445.2 blaDIM updated to NF000445.2 blaDIM_SIM_IMP-NCBI + HMM Modified: NF000446.2 blaCIA updated to NF000446.2 blaCMA-NCBI + HMM Modified: NF000447.2 bla-A_Chryseo updated to NF000447.2 bla-B1-FLAV-NCBI + HMM Modified: NF000448.2 blaACI updated to NF000448.2 blaACT-NCBI + HMM Modified: NF000449.2 blaBIC updated to NF000449.2 blaBJP-NCBI + HMM Modified: NF000450.2 bla-B1-FLAV updated to NF000450.2 bla1-NCBI + HMM Modified: NF000451.2 blaBES updated to NF000451.2 blaBIC-NCBI + HMM Modified: NF000452.2 blaKLUC updated to NF000452.2 blaKPC-NCBI + HMM Modified: NF000453.2 blaPEDO-3_fam updated to NF000453.2 blaPER-NCBI + HMM Modified: NF000454.2 blaCPS updated to NF000454.2 blaCRH-NCBI + HMM Modified: NF000455.2 blaESP-1_fam updated to NF000455.2 blaFEZ-NCBI + HMM Modified: NF000456.2 blaMSI-1_fam updated to NF000456.2 blaMUS-NCBI + HMM Modified: NF000457.2 blaPEDO-1_fam updated to NF000457.2 blaPEDO-2_fam-NCBI + HMM Modified: NF000458.2 blaPEDO-2_fam updated to NF000458.2 blaPEDO-3_fam-NCBI + HMM Modified: NF000459.2 blaSPG-1_fam updated to NF000459.2 blaSPM-NCBI + HMM Modified: NF000460.1 fusD updated to NF000460.1 fusF-NCBI + HMM Modified: NF000461.2 blaOXA-184_like updated to NF000461.2 blaOXA-1_like-NCBI + HMM Modified: NF000462.2 blaOXA-493_like updated to NF000462.2 blaOXA-50_like-NCBI + HMM Modified: NF000463.2 blaOXA_Campylobacter updated to NF000463.2 blaOXY-NCBI + HMM Modified: NF000464.2 blaOXA-143_like updated to NF000464.2 blaOXA-184_like-NCBI + HMM Modified: NF000465.1 polymyxin_MCR1 updated to NF000465.1 polymyxin_MCR2-NCBI + HMM Modified: NF000466.2 16S_rRNA_Rmt_gen updated to NF000466.2 299782349_fosC-NCBI + HMM Modified: NF000467.1 FosG updated to NF000467.1 FosK-NCBI + HMM Modified: NF000468.1 Erm37 updated to NF000468.1 Erm42-NCBI + HMM Modified: NF000469.2 CAR_gen_B3 updated to NF000469.2 CHL_hydrolase-NCBI + HMM Modified: NF000470.1 D_ala_D_lac_VanM updated to NF000470.1 D_ala_D_lac_VanO-NCBI + HMM Modified: NF000471.1 vanY_of_D updated to NF000471.1 vanZ-A-NCBI + HMM Modified: NF000472.1 vanY_AFMPt updated to NF000472.1 vanY_BG-NCBI + HMM Modified: NF000473.1 vanY_BG updated to NF000473.1 vanY_far-NCBI + HMM Modified: NF000474.1 tet_ABC_46_A updated to NF000474.1 tet_ABC_46_B-NCBI + HMM Modified: NF000475.1 tet_ABC_46_B updated to NF000475.1 tet_ABC_AB_A-NCBI + HMM Modified: NF000476.1 myrA updated to NF000476.1 nosihep_NshR-NCBI + HMM Modified: NF000477.1 NshR_TsnR updated to NF000477.1 OKP-NCBI + HMM Modified: NF000478.2 linco_LnuE updated to NF000478.2 linco_LnuF-NCBI + HMM Modified: NF000479.1 zbmA updated to NF000479.1 + HMM Modified: NF000480.2 PSE updated to NF000480.2 P_eth_NH2_trans-NCBI + HMM Modified: NF000481.1 carbeni_gen updated to NF000481.1 chaper_CopP-NCBI + HMM Modified: NF000482.1 AAC_3_XI updated to NF000482.1 AAC_6p_A10-NCBI + HMM Modified: NF000483.1 BlmB updated to NF000483.1 CARB-NCBI + HMM Modified: NF000485.1 TlmB updated to NF000485.1 VanC1_ser_lig-NCBI + HMM Modified: NF000486.1 AAC_6p_Ip updated to NF000486.1 AAC_6p_Iz-NCBI + HMM Modified: NF000487.1 stat updated to NF000487.1 stregra_B_VgbA-NCBI + HMM Modified: NF000488.1 chrB updated to NF000488.1 classA_carba-NCBI + HMM Modified: NF000489.1 ble_Sh updated to NF000489.1 carbeni_gen-NCBI + HMM Modified: NF000490.1 chloram_CatB updated to NF000490.1 chrB-NCBI + HMM Modified: NF000491.1 chloram_CatA updated to NF000491.1 chloram_CatB-NCBI + HMM Modified: NF000492.1 vanH_gen updated to NF000492.1 vanJ-NCBI + HMM Modified: NF000493.1 Fos_BSH updated to NF000493.1 Fos_BSH_Bcer-NCBI + HMM Modified: NF000494.1 FosF updated to NF000494.1 FosG-NCBI + HMM Modified: NF000495.1 FosK updated to NF000495.1 FosL-NCBI + HMM Modified: NF000496.1 Fos_GSH updated to NF000496.1 HARLDQ_not_B3-NCBI + HMM Modified: NF000497.1 AAC_6p_Iak updated to NF000497.1 AAC_6p_Ian-NCBI + HMM Modified: NF000498.2 APH_2pp_If_Ih updated to NF000498.2 APH_2pp_Ig-NCBI + HMM Modified: NF000499.1 Erm23S_rRNA_broad updated to NF000499.1 Erm32-NCBI + HMM Modified: NF000500.2 blaOXA-58_like updated to NF000500.2 blaOXA-60_like-NCBI + HMM Modified: NF000501.2 blaOXA-229_like updated to NF000501.2 blaOXA-22_like-NCBI + HMM Modified: NF000502.2 blaOXA-85_like updated to NF000502.2 blaOXA_Campylobacter-NCBI + HMM Modified: NF000503.1 fusF updated to NF000503.1 fusid_est_FusH-NCBI + HMM Modified: NF000504.1 stregram_VatH updated to NF000504.1 stregram_VatI-NCBI + HMM Modified: NF000505.2 blaGIL updated to NF000505.2 blaGIM-NCBI + HMM Modified: NF000506.1 tet_ABC_AB_A updated to NF000506.1 tet_ABC_AB_B-NCBI + HMM Modified: NF000507.1 AAC_6p_Ie updated to NF000507.1 AAC_6p_Ie_fam-NCBI + HMM Modified: NF000508.1 APH_2pp_Ia updated to NF000508.1 APH_2pp_Ie_IVa-NCBI + HMM Modified: NF000509.1 efflux_CmlA updated to NF000509.1 efflux_Cmx-NCBI + HMM Modified: NF000510.1 efflux_Cmx updated to NF000510.1 efflux_OM_AdeC-NCBI + HMM Modified: NF000511.2 blaCME updated to NF000511.2 blaCMH-NCBI + HMM Modified: NF000512.2 blaSGM updated to NF000512.2 blaSIM-NCBI + HMM Modified: NF000513.2 blaFTU updated to NF000513.2 blaGES-NCBI + HMM Modified: NF000514.1 ABCF_OptrA updated to NF000514.1 ABCF_Sal-NCBI + HMM Modified: NF000516.1 EreD updated to NF000516.1 Erm23S_rRNA_broad-NCBI + HMM Modified: NF000517.2 blaCBP updated to NF000517.2 blaCDD-NCBI + HMM Modified: NF000518.2 blaVCC updated to NF000518.2 blaVEB-NCBI + HMM Modified: NF000519.2 blaPDC_var updated to NF000519.2 blaPEDO-1_fam-NCBI + HMM Modified: NF000520.2 blaOXA-286_like updated to NF000520.2 blaOXA-2_like-NCBI + HMM Modified: NF000531.2 blaTEM updated to NF000531.2 blaTHIN-NCBI + HMM Modified: NF000538.0 classA_carba updated to NF000538.0 classA_firm-NCBI + HMM Modified: NF007456.1 PRK10026.1 updated to NF007456.1 PRK13747.1-PRKfam + HMM Modified: NF010310.2 PRK13747.1 updated to NF010310.2 PRK13752.1-PRKfam + HMM Modified: NF010315.0 PRK13752.1 updated to NF010315.0 PSE-NCBI + HMM Modified: NF012098.1 blaBPU updated to NF012098.1 blaCAM-NCBI + HMM Modified: NF012099.1 SubclassA2 updated to NF012099.1 Sul1-NCBI + HMM Modified: NF012100.0 blaVIM updated to NF012100.0 blaZ-NCBI + HMM Modified: NF012101.1 blaGOB updated to NF012101.1 blaIMI-NCBI + HMM Modified: NF012102.1 blaDHA updated to NF012102.1 blaDIM-NCBI + HMM Modified: NF012103.0 blaGES updated to NF012103.0 blaGIL-NCBI + HMM Modified: NF012137.0 bla_xUS updated to NF012137.0 ble_BLMA_gen-NCBI + HMM Modified: NF012140.0 blaBJP updated to NF012140.0 blaBKC-NCBI + HMM Modified: NF012141.0 blaKPC updated to NF012141.0 blaL-NCBI + HMM Modified: NF012142.0 blaSME updated to NF012142.0 blaSPG-1_fam-NCBI + HMM Modified: NF012143.0 SHV_LEN_OKP updated to NF012143.0 SMB1_fam-NCBI + HMM Modified: NF012145.1 blaDIM_SIM_IMP updated to NF012145.1 blaEBR-NCBI + HMM Modified: NF012146.1 blaB-IND-MUS updated to NF012146.1 blaB-NCBI + HMM Modified: NF012147.1 blaIMP updated to NF012147.1 blaIND-NCBI + HMM Modified: NF012148.0 blaKHM-HMB updated to NF012148.0 blaKLUC-NCBI + HMM Modified: NF012149.0 blaIND updated to NF012149.0 blaKHM-HMB-NCBI + HMM Modified: NF012150.3 blaSPM updated to NF012150.3 blaSRT-NCBI + HMM Modified: NF012151.0 penta_rpt_QnrAS updated to NF012151.0 penta_rpt_QnrB-NCBI + HMM Modified: NF012152.0 penta_rpt_QnrC updated to NF012152.0 penta_rpt_QnrD-NCBI + HMM Modified: NF012153.1 tet_protect updated to NF012153.1 tet_protect_M-NCBI + HMM Modified: NF012154.0 tet_protect_Q updated to NF012154.0 tet_prtrans_34-NCBI + HMM Modified: NF012155.1 tet_protect_M updated to NF012155.1 tet_protect_M_W-NCBI + HMM Modified: NF012156.1 blaP updated to NF012156.1 blaPAC-NCBI + HMM Modified: NF012157.0 ANT_3pp_I updated to NF012157.0 ANT_3pp_II-NCBI + HMM Modified: NF012158.1 macrolide_MphE updated to NF012158.1 macrolide_MphF-NCBI + HMM Modified: NF012159.0 polymyxin_MCR2 updated to NF012159.0 polymyxin_MCR3-NCBI + HMM Modified: NF012160.0 APH_6_Steno updated to NF012160.0 APH_7pp_Ia-NCBI + HMM Modified: NF012161.0 bla_class_D_main updated to NF012161.0 bla_subclass_B1-NCBI + HMM Modified: NF012165.0 AAC_6p_set_A updated to NF012165.0 ABCF_CarA-NCBI + HMM Modified: NF012167.0 classA_firm updated to NF012167.0 cmlA_floR-NCBI + HMM Modified: NF012169.0 qepA updated to NF012169.0 rRNA_meth_EmtA-NCBI + HMM Modified: NF012170.0 qac_SMR_J updated to NF012170.0 qepA-NCBI + HMM Modified: NF012171.0 APH_6 updated to NF012171.0 APH_6_Ic-NCBI + HMM Modified: NF012172.1 FOX-MOX updated to NF012172.1 FexA-NCBI + HMM Modified: NF012173.1 CMY2-MIR-ACT-EC updated to NF012173.1 CMY2-NCBI + HMM Modified: NF012174.0 tet_MFS_A_B_C_D updated to NF012174.0 tet_MFS_B-NCBI + HMM Modified: NF012175.1 tet_MFS_L_K_45 updated to NF012175.1 tet_MFS_OtrB-NCBI + HMM Modified: NF012176.0 tet_MFS_38 updated to NF012176.0 tet_MFS_40-NCBI + HMM Modified: NF012177.1 tet_MFS_42 updated to NF012177.1 tet_MFS_43-NCBI + HMM Modified: NF012178.0 tet_MFS_V updated to NF012178.0 tet_MFS_Y-NCBI + HMM Modified: NF012180.1 tet_MFS_43 updated to NF012180.1 tet_MFS_45-NCBI + HMM Modified: NF012183.0 tet_MFS_K updated to NF012183.0 tet_MFS_L-NCBI + HMM Modified: NF012184.0 tet_MFS_45 updated to NF012184.0 tet_MFS_A-NCBI + HMM Modified: NF012185.0 tet_MFS_L updated to NF012185.0 tet_MFS_L_K_45-NCBI + HMM Modified: NF012186.0 tet_MFS_D updated to NF012186.0 tet_MFS_E-NCBI + HMM Modified: NF012187.0 tet_MFS_E updated to NF012187.0 tet_MFS_G-NCBI + HMM Modified: NF012188.1 tet_MFS_Y updated to NF012188.1 tet_NaH_anti_35-NCBI + HMM Modified: NF012190.1 tet_MFS_B updated to NF012190.1 tet_MFS_C-NCBI + HMM Modified: NF012191.0 tet_MFS_C updated to NF012191.0 tet_MFS_D-NCBI + HMM Modified: NF012192.0 tet_MFS_G updated to NF012192.0 tet_MFS_H-NCBI + HMM Modified: NF012193.0 tet_MFS_A updated to NF012193.0 tet_MFS_A_B_C_D-NCBI + HMM Modified: NF012194.0 tet_MFS_J updated to NF012194.0 tet_MFS_K-NCBI + HMM Modified: NF012195.0 tet_MFS_H updated to NF012195.0 tet_MFS_H_J-NCBI + HMM Modified: NF012199.0 cml_V_MFS updated to NF012199.0 cmx_cmrA-NCBI + HMM Modified: NF012202.0 ble_MBL updated to NF012202.0 ble_Sh-NCBI + HMM Modified: NF012203.0 cmlB1_MFS updated to NF012203.0 cml_V_MFS-NCBI + HMM Modified: NF012207.0 tet_MFS_H_J updated to NF012207.0 tet_MFS_J-NCBI + HMM Modified: NF012212.0 ANT_9 updated to NF012212.0 APH_2pp_IIIa-NCBI + HMM Modified: NF012213.0 VanC1_ser_lig updated to NF012213.0 VarG_fam_MBL-NCBI + HMM Modified: NF012214.1 D_ala_D_ser_VanC updated to NF012214.1 D_ala_D_ser_VanE-NCBI + HMM Modified: NF012215.1 D_ala_D_lac_VanD updated to NF012215.1 D_ala_D_lac_VanF-NCBI + HMM Modified: NF012216.1 D_ala_D_lac_VanB updated to NF012216.1 D_ala_D_lac_VanD-NCBI + HMM Modified: NF012217.1 D_ala_D_lac_VanA updated to NF012217.1 D_ala_D_lac_VanB-NCBI + HMM Modified: NF012218.0 erm_38_23S_MT updated to NF012218.0 erm_A_23S_MT-NCBI + HMM Modified: NF012219.1 erm_C_23S_MT updated to NF012219.1 erm_F_23S_MT-NCBI + HMM Modified: NF012220.1 erm_B_23S_MT updated to NF012220.1 erm_C_23S_MT-NCBI + HMM Modified: NF012222.1 erm_A_23S_MT updated to NF012222.1 erm_B_23S_MT-NCBI + HMM Modified: NF012223.0 erm_F_23S_MT updated to NF012223.0 erm_SHROVE-NCBI + HMM Modified: NF012224.1 blaSFH updated to NF012224.1 blaSFH_gen-NCBI + HMM Modified: NF012225.0 blaSFH_gen updated to NF012225.0 blaSGM-NCBI + HMM Modified: NF012229.1 bla_class_B_core updated to NF012229.1 bla_class_C-NCBI + HMM Modified: NF028535.0 ANT_4p_II updated to NF028535.0 ANT_4p_Ia-NCBI + HMM Modified: NF032892.0 fosA7 updated to NF032892.0 fosA8-NCBI + HMM Modified: NF032894.1 APH_3pp_Ia updated to NF032894.1 APH_3pp_Ib-NCBI + HMM Modified: NF032895.1 APH_3pp_Ib updated to NF032895.1 APH_4_Ia-NCBI + HMM Modified: NF032896.1 APH_3pp updated to NF032896.1 APH_3pp_Ia-NCBI + HMM Modified: NF032897.1 APH_3p_V updated to NF032897.1 APH_3p_VI-NCBI + HMM Modified: NF032898.1 APH_3p_II updated to NF032898.1 APH_3p_IIIa-NCBI + HMM Modified: NF033059.2 APH_3p_I updated to NF033059.2 APH_3p_II-NCBI + HMM Modified: NF033060.0 blaBCL updated to NF033060.0 blaBEL-NCBI + HMM Modified: NF033061.1 ANT_4p_I updated to NF033061.1 ANT_4p_II-NCBI + HMM Modified: NF033062.0 APH_3p_VI updated to NF033062.0 APH_3p_VIII-NCBI + HMM Modified: NF033063.0 APH_3p_XV updated to NF033063.0 APH_3pp-NCBI + HMM Modified: NF033064.0 APH_3p_IIIa updated to NF033064.0 APH_3p_IVa-NCBI + HMM Modified: NF033065.0 APH_3p_IVa updated to NF033065.0 APH_3p_V-NCBI + HMM Modified: NF033066.0 APH_3p_VIII updated to NF033066.0 APH_3p_VIIa-NCBI + HMM Modified: NF033067.1 APH_3p_VIIa updated to NF033067.1 APH_3p_XV-NCBI + HMM Modified: NF033068.1 APH_3p updated to NF033068.1 APH_3p_A16-NCBI + HMM Modified: NF033074.0 AAC_6p_Ib updated to NF033074.0 AAC_6p_Id-NCBI + HMM Modified: NF033075.0 AAC_6p_Steno updated to NF033075.0 AAC_6p_Strep-NCBI + HMM Modified: NF033076.0 AAC_6p_Yersi updated to NF033076.0 AAC_6p_set_A-NCBI + HMM Modified: NF033077.0 AAC_6p_A30 updated to NF033077.0 AAC_6p_A31-NCBI + HMM Modified: NF033078.2 AAC_6p_Ia_fam updated to NF033078.2 AAC_6p_Iad-NCBI + HMM Modified: NF033080.0 AAC_3_II updated to NF033080.0 AAC_3_IV-NCBI + HMM Modified: NF033081.0 AAC_3_IV updated to NF033081.0 AAC_3_VIII-NCBI + HMM Modified: NF033082.0 AAC_3 updated to NF033082.0 AAC_3_I-NCBI + HMM Modified: NF033083.0 AAC_3_I updated to NF033083.0 AAC_3_II-NCBI + HMM Modified: NF033084.2 ANT_6 updated to NF033084.2 ANT_6_aadK-NCBI + HMM Modified: NF033085.1 bla_class_C updated to NF033085.1 bla_class_D_alt-NCBI + HMM Modified: NF033087.1 bla_subclass_B2 updated to NF033087.1 bla_subclass_B3-NCBI + HMM Modified: NF033088.1 bla_subclass_B1 updated to NF033088.1 bla_subclass_B2-NCBI + HMM Modified: NF033089.1 blaCTX-M updated to NF033089.1 blaCcrA-NCBI + HMM Modified: NF033090.1 HK_VanS_B updated to NF033090.1 HK_VanS_O-NCBI + HMM Modified: NF033091.0 HK_VanS_ACDEFG updated to NF033091.0 HK_VanS_B-NCBI + HMM Modified: NF033094.0 HK_VanS_O updated to NF033094.0 L2-NCBI + HMM Modified: NF033095.1 bla_Bc_2 updated to NF033095.1 bla_CblA-NCBI + HMM Modified: NF033096.1 bla1 updated to NF033096.1 blaACC-NCBI + HMM Modified: NF033098.1 bla_CblA updated to NF033098.1 bla_CepA-NCBI + HMM Modified: NF033099.1 bla_Exo updated to NF033099.1 bla_class_A-NCBI + HMM Modified: NF033100.1 bla_CfxA updated to NF033100.1 bla_Exo-NCBI + HMM Modified: NF033101.0 blaL updated to NF033101.0 blaL1-NCBI + HMM Modified: NF033102.1 bla_CepA updated to NF033102.1 bla_CfxA-NCBI + HMM Modified: NF033103.1 bla_class_A updated to NF033103.1 bla_class_B_core-NCBI + HMM Modified: NF033104.0 blaOXA-46_like updated to NF033104.0 blaOXA-48_like-NCBI + HMM Modified: NF033105.1 bla_subclass_B3 updated to NF033105.1 bla_xUS-NCBI + HMM Modified: NF033106.1 blaL1 updated to NF033106.1 blaLAP-NCBI + HMM Modified: NF033107.1 blaB updated to NF033107.1 blaBBI-NCBI + HMM Modified: NF033108.1 sensor_BlaR1 updated to NF033108.1 sensor_MecR1-NCBI + HMM Modified: NF033109.1 sensor_MecR1 updated to NF033109.1 stat-NCBI + HMM Modified: NF033111.2 tet_monoox_X updated to NF033111.2 tet_protect-NCBI + HMM Modified: NF033112.0 APH_3p_A16 updated to NF033112.0 APH_3p_I-NCBI + HMM Modified: NF033114.1 phos_trans_CPT updated to NF033114.1 poly_MCR3_broad-NCBI + HMM Modified: NF033115.1 dipept_VanX updated to NF033115.1 efflux_CmlA-NCBI + HMM Modified: NF033117.2 vanR_ACDEGLN updated to NF033117.2 vanR_FM-NCBI + HMM Modified: NF033118.1 vanR-O updated to NF033118.1 vanR_ACDEGLN-NCBI + HMM Modified: NF033120.0 vanR_FM updated to NF033120.0 vanT-CELN-NCBI + HMM Modified: NF033122.1 vanW-B updated to NF033122.1 vanW-G-NCBI + HMM Modified: NF033123.1 vanW-G updated to NF033123.1 vanW-gen-NCBI + HMM Modified: NF033125.2 vanZ-A updated to NF033125.2 vanZ-F-NCBI + HMM Modified: NF033126.1 ANT_3pp_AadA1 updated to NF033126.1 ANT_3pp_AadA3-NCBI + HMM Modified: NF033127.1 ANT_3pp_AadA3 updated to NF033127.1 ANT_3pp_I-NCBI + HMM Modified: NF033128.2 vanW-gen updated to NF033128.2 vanXY-NCBI + HMM Modified: NF033129.1 macro_glyco_Mgt updated to NF033129.1 macrolide_MefA-NCBI + HMM Modified: NF033130.1 AAC_6p_A48 updated to NF033130.1 AAC_6p_A49-NCBI + HMM Modified: NF033131.1 vanT-G-Cterm updated to NF033131.1 vanT-L-cat-NCBI + HMM Modified: NF033132.1 vanT-CELN updated to NF033132.1 vanT-G-Cterm-NCBI + HMM Modified: NF033133.1 vanT-L-cat updated to NF033133.1 vanT-L-mem-NCBI + HMM Modified: NF033135.1 cmx_cmrA updated to NF033135.1 coreg_MerD-NCBI + HMM Modified: NF033136.1 SMR_qac_K updated to NF033136.1 SMR_qac_bcrB-NCBI + HMM Modified: NF033137.0 SMR_qac_int updated to NF033137.0 SMR_qac_pB8-NCBI + HMM Modified: NF033139.1 blaZ updated to NF033139.1 blaZ_gen-NCBI + HMM Modified: NF033140.0 blaZ_mecC_type updated to NF033140.0 bla_B2_CphA-NCBI + HMM Modified: NF033141.0 blaZ_gen updated to NF033141.0 blaZ_mecC_type-NCBI + HMM Modified: NF033142.1 efflux_OM_AdeC updated to NF033142.1 emrE-Resfams + HMM Modified: NF033144.1 rifampin_ARR updated to NF033144.1 rifampin_ARR_Ms-NCBI + HMM Modified: NF033145.1 rif_monoox updated to NF033145.1 rifampin_ARR-NCBI + HMM Modified: NF033148.1 tet_protect_M_W updated to NF033148.1 tet_protect_Q-NCBI + HMM Modified: NF033149.0 CHL_hydrolase updated to NF033149.0 CMY2-MIR-ACT-EC-NCBI + HMM Modified: NF033150.1 AAC_6p_A49 updated to NF033150.1 AAC_6p_Acine-NCBI + HMM Modified: NF033151.0 AAC_6p_A10 updated to NF033151.0 AAC_6p_A29-NCBI + HMM Modified: NF033152.0 BlaA_Yent updated to NF033152.0 BlaEC-NCBI + HMM Modified: NF033156.1 ble_BLMA_gen updated to NF033156.1 ble_BLMT-NCBI + HMM Modified: NF033159.0 blaPAC updated to NF033159.0 blaPAU-NCBI + HMM Modified: NF033174.0 blaPSV updated to NF033174.0 blaR1_generic-NCBI + HMM Modified: NF033180.1 AAC_3_VIII updated to NF033180.1 AAC_3_VIa-NCBI + HMM Modified: NF033182.0 linco_LnuG updated to NF033182.0 linco_LnuP-NCBI + HMM Modified: NF033204.1 blaRUB updated to NF033204.1 blaSCO-NCBI + HMM Modified: NF033209.1 16S_rRNA_Rmt_B updated to NF033209.1 16S_rRNA_Rmt_C-NCBI + HMM Modified: NF033211.1 blaCRH updated to NF033211.1 blaCSA-NCBI + HMM Modified: NF033220.1 ANT_3pp_II updated to NF033220.1 ANT_4p_I-NCBI + HMM Modified: NF033221.1 aadE-Cc updated to NF033221.1 acid_shock_Asr-NCBI + HMM Modified: NF033374.6 AAC_6p_Id updated to NF033374.6 AAC_6p_Ie-NCBI + HMM Modified: NF033375.2 penta_rpt_QnrE updated to NF033375.2 penta_rpt_QnrS-NCBI + HMM Modified: NF033378.1 MECD_PBP updated to NF033378.1 MFS_efflux_PexA-NCBI + HMM Modified: NF033386.1 blaARL updated to NF033386.1 blaAXC-NCBI + HMM Modified: NF033387.1 ANT_6_aadS updated to NF033387.1 ANT_6_str-NCBI + HMM Modified: NF033398.1 rRNA_meth_EmtA updated to NF033398.1 ribo_prot_ABC_F-NCBI + HMM Modified: NF033405.1 FosL updated to NF033405.1 FosX-NCBI + HMM Modified: NF033406.1 blaMCA updated to NF033406.1 blaMSI-1_fam-NCBI + HMM Modified: NF033408.5 polymyxin_MCR3 updated to NF033408.5 polymyxin_MCR4-NCBI + HMM Modified: NF033409.0 poly_MCR3_broad updated to NF033409.0 polymyxin_MCR1-NCBI + HMM Modified: NF033462.1 polymyxin_MCR4 updated to NF033462.1 polymyxin_MCR5-NCBI + HMM Modified: NF033463.1 polymyxin_MCR5 updated to NF033463.1 polymyxin_MCR6-NCBI + HMM Modified: NF033466.0 blaRCP updated to NF033466.0 blaRHO-NCBI + HMM Modified: NF033467.0 blaAQU updated to NF033467.0 blaARL-NCBI + HMM Modified: NF033468.1 stregram_VatI updated to NF033468.1 tet_ABC_46_A-NCBI + HMM Modified: NF033469.1 SMR_qac_bcrB updated to NF033469.1 SMR_qac_bcrC-NCBI + HMM Modified: NF033470.1 SMR_qac_bcrC updated to NF033470.1 SMR_qac_int-NCBI + HMM Modified: NF033472.1 AAC_2p_IIb updated to NF033472.1 AAC_2p_Ia-NCBI + HMM Modified: NF033473.1 trim_DfrE updated to NF033473.1 trim_DfrF-NCBI + HMM Modified: NF033476.1 tet_destruct updated to NF033476.1 tet_monoox_X-NCBI + HMM Modified: NF033502.0 Sul4 updated to NF033502.0 TlmB-NCBI + HMM Modified: NF033509.1 blaOXA-22_like updated to NF033509.1 blaOXA-23_like-NCBI + HMM Modified: NF033555.1 lyase_MerB updated to NF033555.1 macro_glyco_Mgt-NCBI + HMM Modified: NF033560.1 merT_RC607 updated to NF033560.1 myrA-NCBI + HMM Modified: NF033565.0 trans_MerF updated to NF033565.0 trans_reg_VanU-NCBI + HMM Modified: NF033568.1 blaROB updated to NF033568.1 blaRUB-NCBI + HMM Modified: NF033569.1 blaLHK updated to NF033569.1 blaLUT-NCBI + HMM Modified: NF033574.1 VarG_fam_MBL updated to NF033574.1 Vat_ABCDEFH-NCBI + HMM Modified: NF033575.1 blaRHO updated to NF033575.1 blaROB-NCBI + HMM Modified: NF033582.2 blaALI updated to NF033582.2 blaAQU-NCBI + HMM Modified: NF033584.1 blaPST updated to NF033584.1 blaPSV-NCBI + HMM Modified: NF033585.1 blaTTU updated to NF033585.1 blaTUS-NCBI + HMM Modified: NF033612.0 AAC_3_VIa updated to NF033612.0 AAC_3_XI-NCBI + HMM Modified: NF033613.1 blaOXA-576_like updated to NF033613.1 blaOXA-58_like-NCBI + HMM Modified: NF033614.1 APH_6_Ic_gen updated to NF033614.1 APH_6_Steno-NCBI + HMM Modified: NF033626.1 blaBKC_GPC updated to NF033626.1 blaBPU-NCBI + HMM Modified: NF033627.3 intimin_all updated to NF033627.3 intimin_alpha-NCBI + HMM Modified: NF033636.1 acid_shock_Asr updated to NF033636.1 adeC-adeK-oprM-Resfams + HMM Modified: NF033637.1 transloc_TIR updated to NF033637.1 transport_merC-NCBI + HMM Modified: NF033639.1 intimin_alpha updated to NF033639.1 linco_LnuA-NCBI + HMM Modified: NF033646.1 toxin_EAST1 updated to NF033646.1 trans_MerF-NCBI + HMM Modified: NF033648.1 blaOXA-274_like updated to NF033648.1 blaOXA-286_like-NCBI + HMM Modified: NF033658.1 Shiga_Stx1A updated to NF033658.1 Shiga_Stx1B-NCBI + HMM Modified: NF033659.0 Shiga_Stx1B updated to NF033659.0 Shiga_Stx2A-NCBI + HMM Modified: NF033660.0 Shiga_Stx2B updated to NF033660.0 SubclassA2-NCBI + HMM Modified: NF033661.1 Shiga_Stx2A updated to NF033661.1 Shiga_Stx2B-NCBI + HMM Modified: NF033666.1 blaOXA-727_like updated to NF033666.1 blaOXA-85_like-NCBI + HMM Modified: NF033667.1 blaOXA-55_like updated to NF033667.1 blaOXA-576_like-NCBI + HMM Modified: NF033669.1 polymyxin_MCR8 updated to NF033669.1 polymyxin_MCR9-NCBI + HMM Modified: NF033670.1 polymyxin_MCR6 updated to NF033670.1 polymyxin_MCR7-NCBI + HMM Modified: NF033671.1 polymyxin_MCR7 updated to NF033671.1 polymyxin_MCR8-NCBI + HMM Modified: NF033692.1 APH_2pp_I_a_f_h updated to NF033692.1 APH_2pp_Ia-NCBI + HMM Modified: NF033693.0 AAC_6p_Ie_fam updated to NF033693.0 AAC_6p_If-NCBI + HMM Modified: NF033698.1 blaCSA updated to NF033698.1 blaCTX-M-NCBI + HMM Modified: NF033700.1 blaCMA updated to NF033700.1 blaCME-NCBI + HMM Modified: NF033702.0 blaOXA-12_like updated to NF033702.0 blaOXA-134_like-NCBI + HMM Modified: NF033714.1 blaBBI updated to NF033714.1 blaBCL-NCBI + HMM Modified: NF033727.1 chaperon_ArsD updated to NF033727.1 chloram_CatA-NCBI + HMM Modified: NF033736.1 blaAFM updated to NF033736.1 blaAIM-NCBI + HMM Modified: NF033781.1 chaper_CopP updated to NF033781.1 chaperon_ArsD-NCBI + HMM Modified: NF033783.1 coreg_MerD updated to NF033783.1 cyto_nec_fctrs-NCBI + HMM Modified: NF033784.1 transport_merC updated to NF033784.1 trim_DfrA10-NCBI + HMM Modified: NF033786.1 phenyl_MerG updated to NF033786.1 phos_trans_CPT-NCBI + HMM Modified: NF033815.0 blaOXA-364_like updated to NF033815.0 blaOXA-372_like-NCBI + HMM Modified: NF033818.0 blaOXA-114_like updated to NF033818.0 blaOXA-12_like-NCBI + HMM Modified: NF033834.1 RND_adapt_MexA updated to NF033834.1 RND_perm_OqxB-NCBI + HMM Modified: NF033836.1 polymyxin_MCR9 updated to NF033836.1 qac_MFS_AB-NCBI + HMM Modified: NF033851.1 trim_DfrA35 updated to NF033851.1 trim_DfrA36-NCBI + HMM Modified: NF033866.1 blaCDD updated to NF033866.1 blaCIA-NCBI + HMM Modified: NF033867.1 blaPAU updated to NF033867.1 blaPDC-NCBI + HMM Modified: NF033868.0 trim_DfrA36 updated to NF033868.0 trim_DfrA3b-NCBI + HMM Modified: NF033877.0 arsB_Sta_pI258 updated to NF033877.0 betalact_A_Burk_PenA-NCBI + HMM Modified: NF033895.1 blaCAM updated to NF033895.1 blaCAU-NCBI + HMM Modified: NF033929.1 blaAXC updated to NF033929.1 blaB-IND-MUS-NCBI + HMM Modified: NF033933.0 fosA8 updated to NF033933.0 fusB-NCBI + HMM Modified: TIGR02052.1 TIGR02052 updated to TIGR02052.1 MexE-Resfams + HMM Modified: TIGR02053.1 TIGR02053 updated to TIGR02053.1 MerP-TIGRFAMs +- Protein family changes: + Total: Added 28 + Total: Prev. Release 1499 + Total: Removed 0 + Total: This Release 1527 + Family Added: hmm_id #fam_id + Family Added: - afaC + Family Added: - bin_CdtA + Family Added: - bin_CdtB + Family Added: - bmaE + Family Added: - cvaC + Family Added: - emrD + Family Added: - focG + Family Added: - ibeA + Family Added: - iutA + Family Added: - mcr-10 + Family Added: - papA + Family Added: - papC + Family Added: - papE + Family Added: - papG + Family Added: - papG-I + Family Added: - papG-II + Family Added: - papG-III + Family Added: - papH + Family Added: - sfaF + Family Added: - tcdA + Family Added: - tcdB + Family Added: - tcdC + Family Added: - tcdE + Family Added: - tcdR + Family Added: - tcd_gen + Family Added: - tva(A) + Family Added: - tva(B) + Family Changed: - blaOXA-266_fam updated to NF033653.1 blaOXA-266_fam + +--------------------------------------------------------------------- +Changes included in 2019-09-06.1 +--------------------------------------------------------------------- + +This release just removes two accidentally included "plus" proteins. We +suggest you switch to AMRFinderPlus. See https://github.com/ncbi/amr/wiki for +information an how to install since we will be dropping support for this +version of AMRFinder soon. + +- Protein changes: + Total: Added 0 + Total: Prev. Release 5984 + Total: Removed 2 + Total: This Release 5982 + Protein Removed: AAB91079.1 bind_CopB copper-binding_protein_CopB + Protein Removed: BAB62907.1 cofA type_IV_pilus_CFA/III_major_pilin + +--------------------------------------------------------------------- +Changes included in 2019-09-6.1 +--------------------------------------------------------------------- + +This release removes three erroniously included proteins that were provided by +collaborators, but accidentally released before review by curators. these +sequences do not match the family, gene symbol, or protein name of the +virulence and stress response families to which they had been added. There are +no other changes. + +We will add controls to the database publication system to programmatically +require that curators have manually reviewed all protein sequences before they +become public. + +- Reference Gene Catalog protein and allele changes: + Total in prev: 6274 + Total in release: 6271 + Removed: 3 + Added: 0 + Changed: 0 + Removed copB AAB91079.1 + Removed aaiC AHW84565.1 + Removed cofA BAB62907.1 + +--------------------------------------------------------------------- +Changes included in 2019-08-27.1 +--------------------------------------------------------------------- + +This release includes a new database file to correspond with AMRFinderPlus +version 3.1 that includes information for blacklisting of a few "plus" proteins +common in some organisms that are interesting when found in others. This +release also includes the usual new AMR genes and alleles; the fixing of some +typos; removal of a redundant point mutation reference sequence; and the +addition, reoorganization, and renaming of some "plus" genes. + +- Reference Gene Catalog protein and allele changes: + + Total in prev: 6110 + Total in release: 6274 + Removed: 18 + Added: 182 + Changed: 33 + Removed emrD3 WP_000850833.1 + Removed blaOXA-671 WP_016660101.1 + Removed arsB-mob WP_063116263.1 + Removed gyrA_A67S WP_001281242.1 + Removed gyrA_A84P WP_001281242.1 + Removed gyrA_D87G WP_001281242.1 + Removed gyrA_D87H WP_001281242.1 + Removed gyrA_D87N WP_001281242.1 + Removed gyrA_D87V WP_001281242.1 + Removed gyrA_D87Y WP_001281242.1 + Removed gyrA_G81C WP_001281242.1 + Removed gyrA_H80P WP_001281242.1 + Removed gyrA_N57K WP_001281242.1 + Removed gyrA_Q106H WP_001281242.1 + Removed gyrA_S83F WP_001281242.1 + Removed gyrA_S83I WP_001281242.1 + Removed gyrA_S83L WP_001281242.1 + Removed gyrA_S83W WP_001281242.1 + Added arsB AAA21095.1 + Added arsC AAA21096.1 + Added arsR AAA25636.1 + Added arsB AAA25637.1 + Added copC AAA25808.1 + Added arsR AAA27587.1 + Added arsB AAA27588.1 + Added arsR AAB09624.1 + Added arsC AAB09628.1 + Added arsC AAB42203.1 + Added arsB AAB42204.1 + Added ipaH9.8 AAC23714.1 + Added pic AAD23953.1 + Added efa1 AAD49229.2 + Added iha AAG55323.1 + Added stb AAK29747.1 + Added efa1 AAL57562.1 + Added pic AAN78833.1 + Added iha AAN82058.1 + Added cif AAQ07241.1 + Added iha AAT68782.1 + Added efa1 AAV91321.1 + Added sab AAZ76500.1 + Added senB AAZ89288.1 + Added iha ABB17254.1 + Added emrD3 ABQ18953.1 + Added kdeA ABR76310.1 + Added lmrC ABX00624.1 + Added iha ACB20136.1 + Added iha ACD08748.1 + Added amvA ACQ82816.1 + Added ipaH4 ADA74402.1 + Added iha ADI47068.1 + Added iha ADN47767.1 + Added arsR ADZ44504.1 + Added iha AEQ14190.1 + Added stb AET14866.1 + Added arsR AET17094.1 + Added pic AFS72825.1 + Added iha AFS75030.1 + Added asr BAA15331.2 + Added arsB BAA24823.1 + Added arsC BAA24824.1 + Added espK BAB34991.1 + Added fieF BAB89353.1 + Added fieF BAE77395.1 + Added arsR BAE77793.1 + Added cif BAG66370.1 + Added iha BAI27255.1 + Added efa1 BAI32294.1 + Added iha CAC39288.1 + Added efa1 CAC81883.1 + Added efa1 CAD30848.1 + Added stb CAD87835.1 + Added iha CAE55782.1 + Added efa1 CAI43818.1 + Added hlyA-alpha CAQ77251.1 + Added iha CAR09712.2 + Added pic CAU99295.1 + Added iha CBW53086.1 + Added ipaH5 EID63069.1 + Added fosB WP_000920239.1 + Added dfrA36 WP_000949574.1 + Added mphM WP_001041372.1 + Added cfr(B) WP_002405682.1 + Added mphK WP_003246254.1 + Added blaPDC-374 WP_003454242.1 + Added tet(56) WP_003635403.1 + Added blaCDD-1 WP_009901927.1 + Added mphH WP_015776248.1 + Added erm(49) WP_019728092.1 + Added blaCDD-2 WP_021361759.1 + Added mphN WP_024127776.1 + Added tet(X) WP_024160783.1 + Added blaPDC-361 WP_031638595.1 + Added tet(G) WP_032489471.1 + Added vga(E) WP_032495718.1 + Added blaACT-72 WP_045895620.1 + Added blaACT-70 WP_047364854.1 + Added blaACT-69 WP_048209719.1 + Added ble WP_063842967.1 + Added blaOXA-671 WP_081401608.1 + Added icr-Mo WP_082741435.1 + Added blaOXA-653 WP_087554513.1 + Added tet(X) WP_094309310.1 + Added blaMOX-13 WP_096807444.1 + Added blaFOX-15 WP_096807445.1 + Added blaCMY-157 WP_096807446.1 + Added blaIMP-69 WP_099156051.1 + Added blaPDC-249 WP_104009845.1 + Added blaACT-58 WP_111965422.1 + Added blaACT-62 WP_111967096.1 + Added blaACT-63 WP_112780466.1 + Added blaOXA-727 WP_114272532.1 + Added blaOXA-731 WP_116786833.1 + Added blaOXA-728 WP_116786835.1 + Added blaPDC-367 WP_121286063.1 + Added blaPDC-364 WP_121347819.1 + Added blaFLC-1 WP_123061077.1 + Added blaPDC-371 WP_126118969.1 + Added blaPDC-353 WP_128550481.1 + Added blaVIM-67 WP_142875125.1 + Added blaADC-196 WP_145850033.1 + Added blaAQU WP_148044401.1 + Added blaAQU WP_148044402.1 + Added dfrA29 WP_148044403.1 + Added blaCAM-1 WP_148044405.1 + Added blaCMY-165 WP_148044406.1 + Added blaCMY-166 WP_148044407.1 + Added blaCMY-167 WP_148044408.1 + Added blaCTX-M-227 WP_148044409.1 + Added blaCTX-M-228 WP_148044410.1 + Added blaCTX-M-229 WP_148044411.1 + Added blaDHA-29 WP_148044412.1 + Added blaGES-42 WP_148044413.1 + Added blaGES-43 WP_148044414.1 + Added blaIMP-82 WP_148044416.1 + Added blaIMP-83 WP_148044417.1 + Added blaIMP-84 WP_148044418.1 + Added blaKPC-41 WP_148044419.1 + Added blaKPC-45 WP_148044420.1 + Added blaKPC-46 WP_148044421.1 + Added blaOXA-835 WP_148044422.1 + Added blaOXA-836 WP_148044423.1 + Added blaPAU-1 WP_148044424.1 + Added blaPDC-196 WP_148044425.1 + Added blaPDC-334 WP_148044426.1 + Added blaPDC-335 WP_148044427.1 + Added blaPDC-336 WP_148044428.1 + Added blaPDC-337 WP_148044429.1 + Added blaPDC-338 WP_148044430.1 + Added blaPDC-339 WP_148044431.1 + Added blaPDC-340 WP_148044432.1 + Added blaPDC-341 WP_148044433.1 + Added blaPDC-342 WP_148044434.1 + Added blaPDC-343 WP_148044435.1 + Added blaPDC-344 WP_148044436.1 + Added blaPDC-345 WP_148044437.1 + Added blaPDC-346 WP_148044438.1 + Added blaPDC-347 WP_148044439.1 + Added blaPDC-348 WP_148044440.1 + Added blaPDC-349 WP_148044441.1 + Added blaPDC-350 WP_148044442.1 + Added blaPDC-351 WP_148044443.1 + Added blaPDC-352 WP_148044444.1 + Added blaPDC-354 WP_148044445.1 + Added blaPDC-355 WP_148044446.1 + Added blaPDC-356 WP_148044447.1 + Added blaPDC-357 WP_148044448.1 + Added blaPDC-358 WP_148044449.1 + Added blaPDC-359 WP_148044450.1 + Added blaPDC-360 WP_148044451.1 + Added blaPDC-362 WP_148044452.1 + Added blaPDC-363 WP_148044453.1 + Added blaPDC-365 WP_148044454.1 + Added blaPDC-366 WP_148044455.1 + Added blaPDC-368 WP_148044456.1 + Added blaPDC-369 WP_148044457.1 + Added blaPDC-370 WP_148044458.1 + Added blaPDC-372 WP_148044459.1 + Added blaPDC-373 WP_148044460.1 + Added blaPDC-375 WP_148044461.1 + Added blaPDC-376 WP_148044462.1 + Added blaPDC-377 WP_148044463.1 + Added blaPDC-378 WP_148044464.1 + Added blaPDC-379 WP_148044465.1 + Added blaPDC-380 WP_148044466.1 + Added blaPDC-381 WP_148044467.1 + Added blaPDC-382 WP_148044468.1 + Added blaPDC-383 WP_148044469.1 + Added blaPFM-1 WP_148044470.1 + Added blaTEM-241 WP_148044472.1 + Added blaTEM-242 WP_148044473.1 + Added blaTEM-39 WP_148044474.1 + Added blaVEB-22 WP_148044475.1 + Added blaVIM-68 WP_148044476.1 + Added mcr-1.22 WP_148044477.1 + Added mcr-5.4 WP_148044478.1 + Added blaOXA-837 WP_148281568.1 + Added gyrA_H80P WP_001281243.1 + Added gyrA_N57K WP_001281243.1 + Added gyrA_S83F WP_001281243.1 + Changes: + faeG AAA24032.1 + product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG + faeG AAA24035.1 + product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG + faeG AAA24390.1 + product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG + nccX AAA65102.1 + subclass METAL -> + merB AAA88369.1 + class MECURY -> MERCURY + subclass ORGANOMECURY -> ORGANOMERCURY + merC AAC33908.1 + class MECURY -> MERCURY + subclass ORGANOMECURY -> ORGANOMERCURY + faeG AAC34727.1 + product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG + merB AAC38230.1 + class MECURY -> MERCURY + subclass ORGANOMECURY -> ORGANOMERCURY + merC AAC38233.1 + class MECURY -> MERCURY + subclass ORGANOMECURY -> ORGANOMERCURY + ipaH2 AAN43435.1 + gene_family ipaH9.8 -> ipaH2 + product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 + mreA AAN68577.1 + subclass METAL -> + ipaH2 AAZ87985.1 + gene_family ipaH9.8 -> ipaH2 + product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 + ipaH3 ABB62096.1 + gene_family ipaH9.8 -> ipaH3 + product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH3 + ipaH2 ABB62098.1 + gene_family ipaH9.8 -> ipaH2 + product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 + ipaH2 ABB66229.1 + gene_family ipaH9.8 -> ipaH2 + product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 + ipaH1 ABF02983.1 + gene_family ipaH9.8 -> ipaH1 + product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH1/H6 + ipaH2 ABF04028.1 + gene_family ipaH9.8 -> ipaH2 + product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 + faeG ACB72721.1 + product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG + ipaH2 ACD09076.1 + gene_family ipaH9.8 -> ipaH2 + product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 + faeG AFH14350.1 + product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG + merC BAA14138.2 + class MECURY -> MERCURY + subclass ORGANOMECURY -> ORGANOMERCURY + merB BAA20338.2 + class MECURY -> MERCURY + subclass ORGANOMECURY -> ORGANOMERCURY + merG BAA23166.1 + class MECURY -> MERCURY + merB BAB47641.1 + class MECURY -> MERCURY + subclass ORGANOMECURY -> ORGANOMERCURY + merB CAC86907.1 + class MECURY -> MERCURY + subclass ORGANOMECURY -> ORGANOMERCURY + faeG CAE82650.1 + product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG + faeG CAE82653.1 + product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG + faeG CAE82670.1 + product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG + mphL WP_002047670.1 + gene_family mph(B) -> mphL + product_name Mph(B) family macrolide 2'-phosphotransferase -> macrolide 2'-phosphotransferase MphL + poxtA WP_002415638.1 + genbank_cds_start 1856 -> 57639 + genbank_cds_stop 3484 -> 59267 + genbank_nucleotide_accession MF095097.1 -> MH746818.1 + mcr-3.22 WP_094308975.1 + refseq_nucleotide_accession NG_060581.1 -> NG_060581.2 + blaPDC-259 WP_109791193.1 + genbank_nucleotide_accession MH243333.1 -> MH243333.2 + refseq_nucleotide_accession NG_057591.1 -> NG_057591.2 + blaPDC-265 WP_109791199.1 + genbank_nucleotide_accession MH243339.1 -> MH243339.2 + refseq_nucleotide_accession NG_057597.1 -> NG_057597.2 + +- HMM library Changes: + Total: Added 6 + Total: Prev. Release 603 + Total: Removed 1 + Total: This Release 608 + HMM Removed: NF000274.2 PF04439 + HMM Added: NF007456.1 PRK10026.1 + HMM Added: NF033636.1 acid_shock_Asr + HMM Added: NF033877.0 arsB_Sta_pI258 + HMM Added: NF033895.1 blaCAM + HMM Added: NF033929.1 blaAXC + HMM Added: NF033933.0 fosA8 + +- Protein family changes: + Total: Added 47 + Total: Prev. Release 1454 + Total: Removed 1 + Total: This Release 1500 + Family Removed: - ubiq_IpaH3 + Family Added: - ACID + Family Added: - CDF_efflux + Family Added: - amvA + Family Added: NF033877.0 arsB_pI258 + Family Added: - arsB_pKW301 + Family Added: - arsB_pYV + Family Added: NF007456.1 arsC_gluta + Family Added: - arsR + Family Added: - arsR_K-12 + Family Added: - arsR_R46 + Family Added: - arsR_pI258 + Family Added: - arsR_pKW301 + Family Added: - arsR_pSX267 + Family Added: - arsR_pYV + Family Added: NF033636.1 asr + Family Added: NF033929.1 blaAXC + Family Added: NF033895.1 blaCAM + Family Added: - blaPFM + Family Added: - cif + Family Added: - copC_Psyr + Family Added: - dfrA29 + Family Added: - efa1 + Family Added: - erm(49) + Family Added: - espK + Family Added: - fieF + Family Added: NF033933.0 fosA8 + Family Added: - hlyA-alpha + Family Added: - icr-Mo + Family Added: - iha + Family Added: - ipaH1 + Family Added: - ipaH2 + Family Added: - ipaH3 + Family Added: - ipaH4 + Family Added: - ipaH5 + Family Added: - ipa_gen + Family Added: - kdeA + Family Added: - lmrC_abcf + Family Added: - mphH + Family Added: - mphK + Family Added: - mphL + Family Added: - mphM + Family Added: - mphN + Family Added: - pic_auto + Family Added: - sab + Family Added: - senB + Family Added: - stb + Family Added: - tet(56) + Family Changed: NF000274.2 ant6_gen updated to - ant6_gen + +--------------------------------------------------------------------- +Changes included in 2019-07-10.1 +--------------------------------------------------------------------- + +New alleles and sequences were added, a few product names were made more +specific as more phenotype information became available. Cleanup of the +database caused some families and HMMs not used by AMRFinderPlus to be removed. + +- Protein changes: + Total: Added 57 + Total: Prev. Release 5757 + Total: Removed 3 + Total: This Release 5811 + Protein Removed: WP_029728367.1 blaB BlaB_family_subclass_B1_metallo-beta-lactamase + Protein Removed: WP_063842622.1 blaB BlaB_family_subclass_B1_metallo-beta-lactamase + Protein Removed: WP_063842629.1 blaGOB GOB_family_subclass_B3_metallo-beta-lactamase + Protein Added: AAA21095.1 arsB_R773 arsenite_efflux_transporter_membrane_subunit_ArsB + Protein Added: ABQ18953.1 emrD3 multidrug_efflux_MFS_transporter_EmrD-3 + Protein Added: WP_000850833.1 emrD3 multidrug_efflux_MFS_transporter_EmrD-3 + Protein Added: WP_010446567.1 tet(B) tetracycline_efflux_MFS_transporter_Tet(B) + Protein Added: WP_039902635.1 blaOXA-134_like OXA-134_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-646 + Protein Added: WP_063116263.1 arsB_R773 arsenite_efflux_transporter_membrane_subunit_ArsB + Protein Added: WP_063844329.1 dfrA12 trimethoprim-resistant_dihydrofolate_reductase_DfrA12 + Protein Added: WP_063856066.1 tet(B) tetracycline_efflux_MFS_transporter_Tet(B) + Protein Added: WP_063856068.1 tet(B) tetracycline_efflux_MFS_transporter_Tet(B) + Protein Added: WP_070342370.1 dfrA7 trimethoprim-resistant_dihydrofolate_reductase_DfrA7 + Protein Added: WP_071593205.1 aadA1bt ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA1bt + Protein Added: WP_071593208.1 aadA1bt ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA1bt + Protein Added: WP_086264536.1 blaOXA-213_like OXA-213_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-832 + Protein Added: WP_094323230.1 mcr-2 phosphoethanolamine--lipid_A_transferase_MCR-2.3 + Protein Added: WP_110174956.1 blaTEM class_A_beta-lactamase_TEM-235 + Protein Added: WP_125052736.1 blaOXA-51_like OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-834 + Protein Added: WP_129336087.1 mcr-1 phosphoethanolamine--lipid_A_transferase_MCR-1.19 + Protein Added: WP_135350920.1 blaGES class_A_beta-lactamase_GES-41 + Protein Added: WP_140423191.1 aac(6')-Ib AAC(6')-Ib_family_aminoglycoside_6'-N-acetyltransferase + Protein Added: WP_140423278.1 aadA1 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA1 + Protein Added: WP_140423279.1 aadA2 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA2 + Protein Added: WP_140423280.1 aadA2 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA2 + Protein Added: WP_140423281.1 aadA2 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA2 + Protein Added: WP_140423282.1 aadA5 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA5 + Protein Added: WP_140423283.1 dfrA1 trimethoprim-resistant_dihydrofolate_reductase_DfrA1 + Protein Added: WP_140423284.1 dfrA12 trimethoprim-resistant_dihydrofolate_reductase_DfrA12 + Protein Added: WP_140423285.1 dfrA17 trimethoprim-resistant_dihydrofolate_reductase_DfrA17 + Protein Added: WP_140423286.1 dfrA17 trimethoprim-resistant_dihydrofolate_reductase_DfrA17 + Protein Added: WP_140423287.1 dfrA17 trimethoprim-resistant_dihydrofolate_reductase_DfrA17 + Protein Added: WP_140423305.1 blaADC class_C_beta-lactamase_ADC-195 + Protein Added: WP_140423306.1 blaB subclass_B1_metallo-beta-lactamase_BlaB-15 + Protein Added: WP_140423307.1 blaCMY class_C_beta-lactamase_CMY-164 + Protein Added: WP_140423308.1 blaFRI carbapenem-hydrolyzing_class_A_beta-lactamase_FRI-8 + Protein Added: WP_140423309.1 blaFRI carbapenem-hydrolyzing_class_A_beta-lactamase_FRI-9 + Protein Added: WP_140423310.1 blaIMI carbapenem-hydrolyzing_class_A_beta-lactamase_IMI-19 + Protein Added: WP_140423311.1 blaKPC carbapenem-hydrolyzing_class_A_beta-lactamase_KPC-44 + Protein Added: WP_140423312.1 blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-643 + Protein Added: WP_140423313.1 blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-644 + Protein Added: WP_140423314.1 blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-645 + Protein Added: WP_140423315.1 blaOXA-134_like OXA-134_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-647 + Protein Added: WP_140423316.1 blaOXA-134_like OXA-134_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-648 + Protein Added: WP_140423317.1 blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-650 + Protein Added: WP_140423318.1 blaOXA-143_like OXA-143_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-825 + Protein Added: WP_140423319.1 blaOXA-213_like OXA-213_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-826 + Protein Added: WP_140423320.1 blaOXA-10_like OXA-10_family_class_D_beta-lactamase_OXA-827 + Protein Added: WP_140423321.1 blaOXA-51_like OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-828 + Protein Added: WP_140423322.1 blaOXA-51_like OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-829 + Protein Added: WP_140423323.1 blaOXA-51_like OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-831 + Protein Added: WP_140423324.1 blaOXA-48_like OXA-48_family_class_D_beta-lactamase_OXA-833 + Protein Added: WP_140423325.1 blaPDC class_C_beta-lactamase_PDC-333 + Protein Added: WP_140423326.1 blaPOM subclass_B3_metallo-beta-lactamase_POM-2 + Protein Added: WP_140423327.1 blaVIM subclass_B1_metallo-beta-lactamase_VIM-64 + Protein Added: WP_140423328.1 blaVIM subclass_B1_metallo-beta-lactamase_VIM-65 + Protein Added: WP_140423329.1 mcr-1 phosphoethanolamine--lipid_A_transferase_MCR-1.20 + Protein Added: WP_140423330.1 mcr-1 phosphoethanolamine--lipid_A_transferase_MCR-1.21 + Protein Added: WP_140423331.1 mcr-3 phosphoethanolamine--lipid_A_transferase_MCR-3.26 + Protein Added: WP_140423332.1 mcr-3 phosphoethanolamine--lipid_A_transferase_MCR-3.30 + Protein Modified: ACM67153.1 lamda-2 intimin_type_lambda updated to ACM67153.1 lambda-2 intimin_type_lambda + Protein Modified: WP_001100753.1 blaPER class_A_extended-spectrum_beta-lactamase_PER-1 updated to WP_001100753.1 blaPER inhibitor-resistant_class_A_extended-spectrum_beta-lactamase_PER-1 + Protein Modified: WP_002317273.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_002317273.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR + Protein Modified: WP_002368697.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_002368697.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR + Protein Modified: WP_032489743.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_032489743.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR + Protein Modified: WP_063856719.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_063856719.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR + Protein Modified: WP_063856723.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_063856723.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR + Protein Modified: WP_063856729.1 vanR-O VanO-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_063856729.1 vanR-O VanO-type_vancomycin_resistance_response_regulator_transcription_factor_VanR + Protein Modified: WP_063860636.1 blaKPC carbapenem-hydrolyzing_class_A_beta-lactamase_KPC-14 updated to WP_063860636.1 blaKPC inhibitor-resistant_class_A_extended-spectrum_beta-lactamase_KPC-14 +- AMR HMM library Changes: + Total: Added 5 + Total: Prev. Release 610 + Total: Removed 12 + Total: This Release 603 + HMM Removed: NF000252.1 MexX + HMM Removed: NF000282.2 RND_permease_1 + HMM Removed: NF000314.1 adeB + HMM Removed: NF000315.1 adeC-adeK-oprM + HMM Removed: NF007842.1 PRK10555.1 + HMM Removed: NF011706.2 PRK15127.1 + HMM Removed: NF028537.1 P_eth_NH2_trans + HMM Removed: NF033086.2 penta_rpt_Qnr + HMM Removed: NF033134.0 cmlA_floR + HMM Removed: NF033143.1 efflux_OM_AdeK + HMM Removed: NF033643.1 EspJ_gen + HMM Removed: NF033651.1 cyto_nec_fctrs + HMM Added: NF000478.2 linco_LnuE + HMM Added: NF012180.1 tet_MFS_43 + HMM Added: NF033866.1 blaCDD + HMM Added: NF033867.1 blaPAU + HMM Added: NF033868.0 trim_DfrA36 +- Protein family changes: + Total: Added 11 + Total: Prev. Release 1449 + Total: Removed 6 + Total: This Release 1454 + Family Removed: NF011706.2 acrB + Family Removed: NF007842.1 acrD + Family Removed: NF000314.1 adeB/adeJ + Family Removed: NF033143.1 adeK + Family Removed: - lamda + Family Removed: - lamda-2 + Family Added: - aadA1bt + Family Added: - arsB + Family Added: - arsB_R773 + Family Added: NF033866.1 blaCDD + Family Added: NF033867.1 blaPAU + Family Added: NF033868.0 dfrA36 + Family Added: - emrD3 + Family Added: - lambda + Family Added: - lambda-2 + Family Added: NF000478.2 lnu(E) + Family Added: NF012180.1 tet(43) + Family Changed: NF030466.1 MerP_Gneg updated to TIGR02052.1 MerP_Gneg + Family Changed: NF030467.1 merA updated to TIGR02053.1 merA + + +--------------------------------------------------------------------- +Changes included in 2019-06-18.1 +--------------------------------------------------------------------- + +This the first alpha release of the AMRFinderPlus database. For this and all +following releases there is a distinction between "core" proteins which +correspond to the genes that would previously have been reported by AMRFinder +and "plus" proteins that are new genes and classes of genes. The "core" +designation is given to proteins where we believe their presence is likely to +have an important effect on antimicrobial resistance. + +* Screen for select point mutations for antibiotic resistance from Salmonella, + E. coli, and Campylobacter + * Protein mutations in: 50S_L22 protein, acrB, acrR, basR, cmeR, cyaA, + fabG, fabI, folP, gyrA, gyrB, lon, marR, murA, nfsA, ompF, parC, parE, + pmrA, pmrB, ptsI, ramR, rpoB, rpsL, soxR, soxS, tufA, uhpA, uhpT + * Nucleotide mutations in 16S and 23S rRNA + * Included point mutations are listed in the reference gene database + (https://www.ncbi.nlm.nih.gov/pathogens/isolates#/refgene/) +* New "Plus" genes + * virulence factors + * biocide resistance + * metal resistance + * heat resistance + * acid resistance +* Combined and integrated results from nucleotide and protein searches + +File formats have changed significantly. See https://github.com/evolarjun/amr/wiki +for details. + +Since release 2019-04-29.1 only one change has been made to the core AMR +proteins. Qac's are now categorized under Type STRESS and Subtype BIOCIDE. + +- Protein changes: + Prev. Release: 4942 + This Release: 5718 + Added: 776 + Modified: 0 + + Protein Added: ABF69110.1 eae intimin type beta + Protein Added: ABF69117.1 eae intimin type epsilon + Protein Added: ABF69121.1 eae intimin type epsilon + Protein Added: ABF69122.1 eae intimin type alpha + Protein Added: KYU89760.1 subB subtilase AB5 cytotoxin subunit B + Protein Added: AAG16664.1 perA BFP system transcriptional regulator PerA + Protein Added: AAG16667.1 perA BFP system transcriptional regulator PerA + Protein Added: AAG16676.1 perA BFP system transcriptional regulator PerA + Protein Added: AAB09625.1 arsD arsenite efflux transporter metallochaperone ArsD + Protein Added: AAB09626.1 arsA arsenite efflux transporter ATPase subunit ArsA + Protein Added: CAJ76690.1 stx1Aa Shiga toxin Stx1a subunit A + Protein Added: CAJ76692.1 stx1Aa Shiga toxin Stx1a subunit A + Protein Added: AAA98291.1 terC tellurium resistance membrane protein TerC + Protein Added: AAA98293.1 terE tellurium resistance cAMP binding protein TerE + Protein Added: AAG27731.1 norM sodium-coupled multidrug efflux MATE transporter NorM + Protein Added: ABF02983.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 + Protein Added: ABF04028.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 + Protein Added: BAE98279.1 bfpA bundle-forming pilus major subunit BfpA + Protein Added: BAE98281.1 bfpA bundle-forming pilus major subunit BfpA + Protein Added: CAC14596.1 smeF multidrug efflux RND transporter outer membrane subunit SmeF + Protein Added: AAA83973.1 merR1 mercury resistance transcriptional regulator MerR1 + Protein Added: AAA83975.1 merT mercuric transport protein MerT + Protein Added: AAA98292.1 terD tellurium resistance membrane protein TerD + Protein Added: AAG34504.1 perA BFP system transcriptional regulator PerA + Protein Added: APX31172.1 yfdX1 heat resistance protein YfdX1 + Protein Added: APX31174.1 hdeD-GI heat resistance membrane protein HdeD-GI + Protein Added: APX31176.1 trxLHR heat resistance system thioredoxin Trx-GI + Protein Added: APX31177.1 kefB-GI heat resistance system K+/H+ antiporter KefB-GI + Protein Added: APX31178.1 psi-GI heat resistance protein PsiE-GI + Protein Added: AAA85087.1 f17a F17A fimbrial adhesin + Protein Added: AAA85196.1 cnf1 cytotoxic necrotizing factor CNF1 + Protein Added: AAG37043.1 espC serine protease autotransporter toxin EspC + Protein Added: ABI93207.1 fedF F18 fimbrial adhesin subunit FedF + Protein Added: BAF33872.1 capU putative hexosyltransferase CapU + Protein Added: BAF33878.1 aggR aggregative adherence transcriptional regulator AggR + Protein Added: BAF33885.1 sepA serine protease autotransporter toxin SepA + Protein Added: BAF33888.1 agg4D aggregative adherence fimbria 4 chaperone Agg4D/HdaD + Protein Added: BAF33891.1 agg4A aggregative adherence fimbria 4 major subunit Agg4A/HdaA + Protein Added: BAF33901.1 aatA dispersin export ABC transporter outer membrane protein AatA + Protein Added: BAF34018.1 aap dispersin Aap + Protein Added: ABJ00546.1 iss increased serum survival lipoprotein Iss + Protein Added: ABJ02430.1 ireA TonB-dependent siderophore receptor IreA + Protein Added: OPH66324.1 lpfA1 long polar fimbria major subunit LpfA1 + Protein Added: ABJ90288.1 fedF F18 fimbrial adhesin subunit FedF + Protein Added: AAA86846.1 terZ tellurium resistance-associated protein TerZ + Protein Added: ABC67318.2 stx2Aa Shiga toxin Stx2a subunit A + Protein Added: AAG40758.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAA88371.1 merE broad-spectrum mercury transporter MerE + Protein Added: AAG42788.1 perA BFP system transcriptional regulator PerA + Protein Added: ASF80766.1 yfdX2 heat resistance protein YfdX2 + Protein Added: ASF80771.1 shsP small heat shock protein sHSP20-GI + Protein Added: CAM11313.1 nleA type III secretion system effector NleA + Protein Added: CAM11314.1 nleA type III secretion system effector NleA + Protein Added: CAM11315.1 nleA type III secretion system effector NleA + Protein Added: CAM11317.1 nleA type III secretion system effector NleA + Protein Added: CAM11321.1 nleA type III secretion system effector NleA + Protein Added: CAM11323.1 nleA type III secretion system effector NleA + Protein Added: CAM11324.1 nleA type III secretion system effector NleA + Protein Added: CAM11325.1 nleA type III secretion system effector NleA + Protein Added: AAA92618.1 f17a F17A fimbrial adhesin + Protein Added: AAA92621.1 f17g F17G fimbrial adhesin + Protein Added: AAA93060.1 arsD arsenite efflux transporter metallochaperone ArsD + Protein Added: AAG53662.1 perA BFP system transcriptional regulator PerA + Protein Added: BAF45432.1 tccP Tir-cytoskeleton coupling protein TccP + Protein Added: BAF45437.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF45439.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF45440.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF45447.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF45451.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF45459.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: ABM90581.1 perA BFP system transcriptional regulator PerA + Protein Added: ABM90583.1 perA BFP system transcriptional regulator PerA + Protein Added: ABM90587.1 perA BFP system transcriptional regulator PerA + Protein Added: ABM90589.1 perA BFP system transcriptional regulator PerA + Protein Added: ABM90597.1 perA BFP system transcriptional regulator PerA + Protein Added: ABM90605.1 perA BFP system transcriptional regulator PerA + Protein Added: ABM90615.1 perA BFP system transcriptional regulator PerA + Protein Added: AAC46147.1 yfeA iron/manganese ABC transporter substrate-binding protein YfeA + Protein Added: AAC46148.1 yfeB iron/manganese ABC transporter ATP-binding protein YfeB + Protein Added: AAC46150.1 yfeD iron/manganese ABC transporter permease subunit YfeD + Protein Added: ATE69525.1 acr3 arsenite efflux transporter Acr3 + Protein Added: AAG55141.1 nleC type III secretion system effector zinc metalloprotease NleC + Protein Added: AAG56990.1 espJ type III secretion system effector ADP-ribosyltransferase EspJ + Protein Added: AAG58695.1 lpfA1 long polar fimbria major subunit LpfA1 + Protein Added: AAG58814.1 espF type III secretion system LEE effector EspF + Protein Added: AAG58818.1 espB type III secretion system LEE translocon pore-forming subunit EspB + Protein Added: AAG58825.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAK15050.1 ttgR efflux transport transcriptional regulator TtgR + Protein Added: AAK16940.1 nleA type III secretion system effector NleA + Protein Added: AAK17180.1 nfaE Dr family non-fimbrial adhesin I chaperone NfaE + Protein Added: AAK18385.1 sepA serine protease autotransporter toxin SepA + Protein Added: AAK18444.1 ipaD type III secretion system needle tip complex protein IpaD + Protein Added: BAB37280.1 nleB type III secretion system effector arginine glycosyltransferase NleB + Protein Added: BAB38093.1 lpfA2 long polar fimbria major subunit LpfA2 + Protein Added: AAC44736.1 terW tellurium resistance protein TerW + Protein Added: AVL28824.1 aar AggR-activated transcriptional regulator Aar + Protein Added: SPD96882.1 silS copper/silver sensor histidine kinase SilS + Protein Added: SPD96883.1 silR copper/silver response regulator transcription factor SilR + Protein Added: SPD96884.1 silC Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC + Protein Added: CAA57177.1 stx2Ae Shiga toxin Stx2e subunit A + Protein Added: CAA57175.1 stx2Ae Shiga toxin Stx2e subunit A + Protein Added: CAA57173.1 stx2Ae Shiga toxin Stx2e subunit A + Protein Added: CAA57171.1 stx2Ae Shiga toxin Stx2e subunit A + Protein Added: BAB43874.1 cadD cadmium resistance transporter CadD + Protein Added: AAK48830.1 cadR cadmium resistance transcriptional regulator CadR + Protein Added: BAF52034.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF52035.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF52033.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF52358.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF52360.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF52362.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF52363.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF52364.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF52365.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF52366.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF52367.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF52370.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF52374.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF52377.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAF52548.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: BAF52549.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: BAB47641.1 merB organomercurial lyase MerB + Protein Added: AAK56853.1 chrR class I chromate reductase ChrR + Protein Added: CAC39286.1 espI serine protease autotransporter EspI + Protein Added: AAA83977.1 merA mercury(II) reductase + Protein Added: AAA23405.1 fasA F6 fimbrial major subunit FasA + Protein Added: AAA23421.1 fim41a fimbrial adhesin F41 protein Fim41a + Protein Added: AAK66972.1 stx2Ad Shiga toxin Stx2d subunit A + Protein Added: AAC41416.1 cfaC CFA/I pilus usher protein CfaC + Protein Added: CAB54534.2 mchB microcin H47 + Protein Added: AAK69562.1 srpS solvent efflux transporter transcriptional repressor SrpS + Protein Added: AAA23734.1 fedA F18 fimbrial major subunit FedA + Protein Added: ABQ02454.1 eae intimin type rho + Protein Added: AAA24032.1 faeG F4 fimbrial adhesin subunit FaeG + Protein Added: AAA24035.1 faeG F4 fimbrial adhesin subunit FaeG + Protein Added: AAA24390.1 faeG F4 fimbrial adhesin subunit FaeG + Protein Added: AXV27948.1 agg3C aggregative adherence fimbria 3 usher protein Agg3C + Protein Added: AAA19189.1 stx2Ae Shiga toxin Stx2e subunit A + Protein Added: AAA19190.1 stx2Be Shiga toxin Stx2e subunit B + Protein Added: AAA24632.1 stx2Af Shiga toxin Stx2f subunit A + Protein Added: AAA24633.1 stx2Bf Shiga toxin Stx2f subunit B + Protein Added: AAA71893.1 stx1Aa Shiga toxin Stx1a subunit A + Protein Added: AAA71894.1 stx1Ba Shiga toxin Stx1a subunit B + Protein Added: AAA24653.1 sta1 heat-stable enterotoxin ST-I group a + Protein Added: ABR09925.1 stx2Ba Shiga toxin Stx2a subunit B + Protein Added: ABR09934.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: ABR09935.1 stx2Bc Shiga toxin Stx2c subunit B + Protein Added: ABR09936.1 stx2Ad Shiga toxin Stx2d subunit A + Protein Added: ABR09937.1 stx2Bd Shiga toxin Stx2d subunit B + Protein Added: ABR09945.1 stx2Ba Shiga toxin Stx2a subunit B + Protein Added: ABR09961.1 stx2Ba Shiga toxin Stx2a subunit B + Protein Added: ABR09963.1 stx2Ba Shiga toxin Stx2a subunit B + Protein Added: ABR10024.1 stx2Ab Shiga toxin Stx2b subunit A + Protein Added: CAA30714.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: CAA30715.1 stx2Ba Shiga toxin Stx2a subunit B + Protein Added: AAB59075.1 merT mercuric transport protein MerT + Protein Added: AAA88369.1 merB organomercurial lyase MerB + Protein Added: AAA88370.1 merD mercury resistance co-regulator MerD + Protein Added: AAA98222.1 merT mercuric transport protein MerT + Protein Added: AAA98223.1 merP mercury resistance system periplasmic binding protein MerP + Protein Added: AAA25638.1 arsC thioredoxin-dependent arsenate reductase + Protein Added: AAA88432.1 chrA chromate resistance efflux protein ChrA + Protein Added: AAA25803.1 copR heavy metal response regulator transcription factor CopR + Protein Added: AAA25804.1 copS copper resistance membrane spanning protein CopS + Protein Added: AAA25806.1 copA laccase-like oxidase CopA + Protein Added: AAA25807.1 copB copper-binding protein CopB + Protein Added: CAC48396.1 stx2Ab Shiga toxin Stx2b subunit A + Protein Added: CAC48398.1 stx2Ae Shiga toxin Stx2e subunit A + Protein Added: AAA21094.1 arsA arsenite efflux transporter ATPase subunit ArsA + Protein Added: BAB62897.1 cofA type IV pilus CFA/III major pilin + Protein Added: BAB62907.1 cofA type IV pilus CFA/III major pilin + Protein Added: CAA63849.1 ehxA enterohemolysin + Protein Added: AAA26402.1 klaB tellurium resistance system protein klaB + Protein Added: AAA26403.1 klaC tellurium resistance system protein klaC + Protein Added: AAK97136.1 cfaC CFA/I pilus usher protein CfaC + Protein Added: AAK99679.1 pmrA multidrug efflux MFS transporter PmrA + Protein Added: CAC69248.1 merR mercury resistance transcriptional regulator MerR + Protein Added: CAC69249.1 merT mercuric transport protein MerT + Protein Added: CAC69250.1 merP mercury resistance system periplasmic binding protein MerP + Protein Added: CAC69251.1 merA mercury(II) reductase + Protein Added: BAB64566.1 bexA multidrug efflux MATE transporter BexA + Protein Added: AAA27589.1 arsC thioredoxin-dependent arsenate reductase + Protein Added: ABU55302.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: BAF76383.1 ttgA toluene efflux RND transporter periplasmic adaptor subunit TtgA + Protein Added: BAF76384.1 ttgB multidrug efflux RND transporter permease subunit TtgB + Protein Added: ABV01314.1 ltcA heat-labile enterotoxin LT subunit A + Protein Added: BAF79679.1 smdA multidrug efflux ABC transporter permease/ATP-binding subunit SmdA + Protein Added: BAF79680.1 smdB multidrug efflux ABC transporter permease/ATP-binding subunit SmdB + Protein Added: ABV16438.1 eatA serine protease autotransporter toxin EatA + Protein Added: BAB68369.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: BAB68370.1 stx2Bc Shiga toxin Stx2c subunit B + Protein Added: BAF80121.1 ssmE multidrug efflux SMR transporter SsmE + Protein Added: AAL06376.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAL06381.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: AAL06387.1 espF type III secretion system LEE effector EspF + Protein Added: AAC23256.1 hmrM sodium-coupled multidrug efflux MATE transporter HmrM + Protein Added: ABQ02442.1 ehxA enterohemolysin + Protein Added: ABQ02443.1 ehxA enterohemolysin + Protein Added: ABQ02445.1 ehxA enterohemolysin + Protein Added: ABQ02447.1 ehxA enterohemolysin + Protein Added: ABQ02448.1 ehxA enterohemolysin + Protein Added: AAL08400.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF + Protein Added: BAF92845.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAL14441.1 adeC multidrug efflux RND transporter AdeABC outer membrane channel subunit AdeC + Protein Added: CAP17609.1 stx2Ae Shiga toxin Stx2e subunit A + Protein Added: CAP17610.1 stx2Be Shiga toxin Stx2e subunit B + Protein Added: AAL18821.1 epeA serine protease autotransporter EpeA + Protein Added: AAL19305.1 mdsB multidrug efflux RND transporter permease subunit MdsB + Protein Added: AAL19306.1 mdsA multidrug efflux RND transporter periplasmic adaptor subunit MdsA + Protein Added: AAL19307.1 golT gold/copper-translocating P-type ATPase GolT + Protein Added: AAL19308.1 golS Au(I) sensor transcriptional regulator GolS + Protein Added: BAF96525.1 espJ type III secretion system effector ADP-ribosyltransferase EspJ + Protein Added: BAF96538.1 nleB2 type III secretion system effector arginine glycosyltransferase NleB2 + Protein Added: BAF96541.1 nleA type III secretion system effector NleA + Protein Added: BAA18405.1 acr3 arsenite efflux transporter Acr3 + Protein Added: BAA18407.1 arsC thioredoxin-dependent arsenate reductase + Protein Added: AAL26283.1 saa autoagglutinating adhesin Saa + Protein Added: CAA65654.1 espB type III secretion system LEE translocon pore-forming subunit EspB + Protein Added: AAC45964.1 stx2Ae Shiga toxin Stx2e subunit A + Protein Added: AAC45965.1 stx2Be Shiga toxin Stx2e subunit B + Protein Added: ACA34793.1 tsh temperature-sensitive protease autotransporter hemagglutinin Tsh + Protein Added: BAG11995.1 tccP Tir-cytoskeleton coupling protein TccP + Protein Added: BAG11997.1 tccP Tir-cytoskeleton coupling protein TccP + Protein Added: BAG12001.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: ACB16424.1 lpfA long polar fimbria major subunit LpfA-O113 + Protein Added: ACB16655.1 eilA HilA family transcriptional regulator EilA + Protein Added: ACB17037.1 air inverse autotransporter adhesin EaeX/Air + Protein Added: CAA70196.1 merT mercuric transport protein MerT + Protein Added: ACB72721.1 faeG F4 fimbrial adhesin subunit FaeG + Protein Added: AAC44731.1 espC serine protease autotransporter toxin EspC + Protein Added: AAC74250.1 ymgB biofilm/acid-resistance regulator AriR + Protein Added: AAC76298.1 acrF multidrug efflux RND transporter permease subunit AcrF + Protein Added: AAC77293.1 mdtM multidrug efflux MFS transporter MdtM + Protein Added: AAL57565.1 nleB type III secretion system effector arginine glycosyltransferase NleB + Protein Added: BAB82994.1 stx2Ab Shiga toxin Stx2b subunit A + Protein Added: BAB82996.1 stx2Ab Shiga toxin Stx2b subunit A + Protein Added: BAB82998.1 stx2Ab Shiga toxin Stx2b subunit A + Protein Added: BAB83000.1 stx2Ab Shiga toxin Stx2b subunit A + Protein Added: BAB83002.1 stx2Ag Shiga toxin Stx2g subunit A + Protein Added: BAB83003.1 stx2Bg Shiga toxin Stx2g subunit B + Protein Added: BAB83005.1 stx2Bb Shiga toxin Stx2b subunit B + Protein Added: BAB83007.1 stx2Bb Shiga toxin Stx2b subunit B + Protein Added: BAB83020.1 stx2Ag Shiga toxin Stx2g subunit A + Protein Added: BAB83022.1 stx1Ac Shiga toxin Stx1c subunit A + Protein Added: BAB83023.1 stx1Bc Shiga toxin Stx1c subunit B + Protein Added: BAB83024.1 stx2Ab Shiga toxin Stx2b subunit A + Protein Added: AAL72309.1 sepA serine protease autotransporter toxin SepA + Protein Added: AAL72350.1 ipaD type III secretion system needle tip complex protein IpaD + Protein Added: AAL05407.1 tcrB copper-translocating P-type ATPase TcrB + Protein Added: ACD06066.1 capU putative hexosyltransferase CapU + Protein Added: ACD06132.1 ipaD type III secretion system needle tip complex protein IpaD + Protein Added: ACD07996.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 + Protein Added: ACD09076.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 + Protein Added: BAA11821.1 chrR class I chromate reductase ChrR + Protein Added: CAQ45062.1 emrC multidrug efflux transporter outer membrane subunit EmrC + Protein Added: CAQ45063.1 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA + Protein Added: CAQ45064.1 emrB multidrug efflux MFS transporter permease subunit EmrB + Protein Added: ACF05260.1 agg4A aggregative adherence fimbria 4 major subunit Agg4A/HdaA + Protein Added: ACF30254.1 mtrR multidrug efflux system transcriptional repressor MtrR + Protein Added: ACF30256.1 mtrF AbgT family antimetabolite efflux transporter MtrF + Protein Added: BAG66379.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAG66729.1 espB type III secretion system LEE translocon pore-forming subunit EspB + Protein Added: BAG66736.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: ACG59623.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: ACG59674.1 espB type III secretion system LEE translocon pore-forming subunit EspB + Protein Added: ACG59676.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: ACG59681.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: ACG59730.1 espB type III secretion system LEE translocon pore-forming subunit EspB + Protein Added: ACG59732.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: ACG59737.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: ACG76368.1 arsP organoarsenical efflux permease ArsP + Protein Added: ACI12150.1 terB tellurium resistance membrane protein TerB + Protein Added: BAG76115.1 iss increased serum survival lipoprotein Iss + Protein Added: AAA98099.1 stx1Aa Shiga toxin Stx1a subunit A + Protein Added: CAS08589.1 nleB2 type III secretion system effector arginine glycosyltransferase NleB2 + Protein Added: CAS08990.1 nleA type III secretion system effector NleA + Protein Added: CAS10463.1 espC serine protease autotransporter toxin EspC + Protein Added: CAS06720.1 eae intimin type gamma + Protein Added: CAS06721.1 eae intimin type alpha + Protein Added: CAS06723.1 eae intimin type alpha + Protein Added: BAA20334.1 merR mercury resistance transcriptional regulator MerR + Protein Added: BAA20336.1 merP mercury resistance system periplasmic binding protein MerP + Protein Added: BAA20337.1 merA mercury(II) reductase + Protein Added: AAM70045.1 stx2Aa Shiga toxin Stx2a subunit A + Protein Added: CAQ87187.1 iroN siderophore salmochelin receptor IroN + Protein Added: CAV00478.1 lpfA long polar fimbria major subunit LpfA + Protein Added: CAV00812.1 lpfA long polar fimbria major subunit LpfA-O113 + Protein Added: CAV02025.1 capU putative hexosyltransferase CapU + Protein Added: CAQ90194.1 iss increased serum survival lipoprotein Iss + Protein Added: CAU95796.1 aatA dispersin export ABC transporter outer membrane protein AatA + Protein Added: CAU95824.1 agg3D aggregative adherence fimbria 3 chaperone Agg3D + Protein Added: CAQ97644.1 iss increased serum survival lipoprotein Iss + Protein Added: CAR01635.1 vactox vacuolating autotransporter toxin Vat + Protein Added: CAR09703.2 ireA TonB-dependent siderophore receptor IreA + Protein Added: CAR12622.1 iss increased serum survival lipoprotein Iss + Protein Added: CAR15326.1 air inverse autotransporter adhesin EaeX/Air + Protein Added: CAW30811.1 nfaE Dr family non-fimbrial adhesin I chaperone NfaE + Protein Added: CAW30815.1 nfaE Dr family non-fimbrial adhesin I chaperone NfaE + Protein Added: ACL13561.1 copR heavy metal response regulator transcription factor CopR + Protein Added: ACL13562.1 copS copper resistance membrane spanning protein CopS + Protein Added: ACL51961.1 ehxA enterohemolysin + Protein Added: ACL51990.1 toxB toxin B + Protein Added: AAM88296.1 agg3C aggregative adherence fimbria 3 usher protein Agg3C + Protein Added: AAM88297.1 agg3B aggregative adherence fimbria 3 minor subunit Agg3B + Protein Added: AAM88298.1 agg3A aggregative adherence fimbria 3 major subunit Agg3A + Protein Added: AAM88299.1 astA heat-stable enterotoxin EAST1 + Protein Added: AAM88302.1 stx2Ad Shiga toxin Stx2d subunit A + Protein Added: BAA14138.2 merC organomercurial transporter MerC + Protein Added: AAM88668.1 cueA copper resistance metal-translocating P1-type ATPase CueA + Protein Added: AAM90978.1 stx2Ba Shiga toxin Stx2a subunit B + Protein Added: CAX18553.1 nleB type III secretion system effector arginine glycosyltransferase NleB + Protein Added: CAX18626.1 nleB type III secretion system effector arginine glycosyltransferase NleB + Protein Added: CAX18635.1 espF type III secretion system LEE effector EspF + Protein Added: CAX18641.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: CAX18646.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: CAX18721.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: CAX18726.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: ACM67143.1 eae intimin type alpha + Protein Added: ACM67145.1 eae intimin type iota + Protein Added: ACM67146.1 eae intimin type alpha + Protein Added: ACM67148.1 eae intimin type gamma + Protein Added: ACM67149.1 eae intimin type gamma + Protein Added: ACM67152.1 eae intimin type beta + Protein Added: ACM67153.1 eae intimin type lambda + Protein Added: ACM67154.1 eae intimin type gamma + Protein Added: ACM67155.1 eae intimin type epsilon + Protein Added: ACM67156.1 eae intimin type epsilon + Protein Added: ACM67157.1 eae intimin type beta + Protein Added: ACM67158.1 eae intimin type epsilon + Protein Added: ACM67160.1 eae intimin type beta + Protein Added: ACM67161.1 eae intimin type beta + Protein Added: ACM67162.1 eae intimin type gamma + Protein Added: ACM67163.1 eae intimin type rho + Protein Added: ACM67164.1 eae intimin type gamma + Protein Added: ACM67165.1 eae intimin type gamma + Protein Added: ACM67166.1 eae intimin type gamma + Protein Added: ACM67167.1 eae intimin type epsilon + Protein Added: ACM67168.1 eae intimin type alpha + Protein Added: ACM67169.1 eae intimin type gamma + Protein Added: ACM67172.1 eae intimin type epsilon + Protein Added: ACM67177.1 eae intimin type gamma + Protein Added: ACM67178.1 eae intimin type epsilon + Protein Added: BAH24012.1 toxB toxin B + Protein Added: CAB14520.2 acr3 arsenite efflux transporter Acr3 + Protein Added: ACO06752.1 emhB efflux RND transporter permease subunit EmhB + Protein Added: AAN03785.1 cnf1 cytotoxic necrotizing factor CNF1 + Protein Added: AAN03786.1 cnf1 cytotoxic necrotizing factor CNF1 + Protein Added: AAN04250.1 dpsA non-specific DNA-binding protein DpsA + Protein Added: BAC10987.1 stx1Ac Shiga toxin Stx1c subunit A + Protein Added: BAC10988.1 stx1Bc Shiga toxin Stx1c subunit B + Protein Added: BAC10992.1 stx1Bc Shiga toxin Stx1c subunit B + Protein Added: CAY54182.1 bfpA bundle-forming pilus major subunit BfpA + Protein Added: AAN29240.1 bepD multidrug efflux RND transporter periplasmic adaptor subunit BepD + Protein Added: AAN29241.1 bepE multidrug efflux RND transporter permease subunit BepE + Protein Added: AAN29871.1 bepC multidrug efflux RND transporter outer membrane subunit BepC + Protein Added: AAN33534.1 bepG multidrug efflux RND transporter permease subunit BepG + Protein Added: AAN33535.1 bepF multidrug efflux RND transporter periplasmic adaptor subunit BepF + Protein Added: CAD48850.1 cdtB cytolethal distending toxin type III/V nuclease subunit CdtB + Protein Added: CAC86907.1 merB organomercurial lyase MerB + Protein Added: BAH65949.1 iroN siderophore salmochelin receptor IroN + Protein Added: BAH72965.1 cdtB cytolethal distending toxin type II nuclease subunit CdtB + Protein Added: AAN42986.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 + Protein Added: AAN43435.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 + Protein Added: AAN44449.1 sigA serine protease autotransporter toxin SigA + Protein Added: CAQ68302.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: ACS88189.1 ipaD type III secretion system needle tip complex protein IpaD + Protein Added: AAC45719.1 f17a F17A fimbrial adhesin + Protein Added: AAC45722.1 f17g F17G fimbrial adhesin + Protein Added: AAN68576.1 mrdH Ni(II)/Co(II) efflux transporter permease subunit MrdH + Protein Added: AAN68577.1 mreA metal-sensing transcriptional repressor MreA + Protein Added: ACT33468.1 f17a F17A fimbrial adhesin + Protein Added: ACT33471.1 f17g F17G fimbrial adhesin + Protein Added: ACT72391.1 tccP Tir-cytoskeleton coupling protein TccP + Protein Added: CAR47993.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: CAR48009.1 nleB type III secretion system effector arginine glycosyltransferase NleB + Protein Added: BAH86759.1 stx2Af Shiga toxin Stx2f subunit A + Protein Added: BAH86760.1 stx2Bf Shiga toxin Stx2f subunit B + Protein Added: BAA20338.2 merB organomercurial lyase MerB + Protein Added: ACU32684.1 stx2Aa Shiga toxin Stx2a subunit A + Protein Added: ACU65296.1 merA mercury(II) reductase + Protein Added: CAX45702.1 stx2Ae Shiga toxin Stx2e subunit A + Protein Added: CAX45706.1 stx2Ad Shiga toxin Stx2d subunit A + Protein Added: CAX45714.1 stx2Ae Shiga toxin Stx2e subunit A + Protein Added: CAX45718.1 stx2Ae Shiga toxin Stx2e subunit A + Protein Added: CAX45737.1 stx2Bd Shiga toxin Stx2d subunit B + Protein Added: CAX45739.1 stx2Ba Shiga toxin Stx2a subunit B + Protein Added: CAX45746.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: CAX51714.1 stx2Ae Shiga toxin Stx2e subunit A + Protein Added: AAB82330.1 aafA aggregative adherence fimbria II major subunit AafA + Protein Added: BAI25473.1 nleC type III secretion system effector zinc metalloprotease NleC + Protein Added: BAI31154.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: BAI32292.1 nleB type III secretion system effector arginine glycosyltransferase NleB + Protein Added: BAI32327.1 espB type III secretion system LEE translocon pore-forming subunit EspB + Protein Added: BAI32516.1 espI serine protease autotransporter EspI + Protein Added: BAI33940.1 etpD variant type II secretion system secretin EtpD + Protein Added: BAI36256.1 nleC type III secretion system effector zinc metalloprotease NleC + Protein Added: BAI36790.1 nleA type III secretion system effector NleA + Protein Added: BAI37513.1 nleB type III secretion system effector arginine glycosyltransferase NleB + Protein Added: BAI37519.1 espF type III secretion system LEE effector EspF + Protein Added: BAI37525.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: BAA23166.1 merG phenylmercury resistance protein MerG + Protein Added: AAN76093.1 iroN siderophore salmochelin receptor IroN + Protein Added: AAN77057.1 stx2Ad Shiga toxin Stx2d subunit A + Protein Added: AAN77061.1 stx2Ad Shiga toxin Stx2d subunit A + Protein Added: AAN77063.1 stx2Ad Shiga toxin Stx2d subunit A + Protein Added: BAI44131.1 agg5A aggregative adherence fimbria V major subunit Agg5A + Protein Added: AAD12176.1 srpB solvent efflux RND transporter permease subunit SrpB + Protein Added: AAD12177.1 ttgI solvent efflux RND transporter outer membrane subunit SrpC + Protein Added: AAD12178.1 srpA solvent efflux RND transporter periplasmic adaptor subunit SrpA + Protein Added: AAN78874.1 vactox vacuolating autotransporter toxin Vat + Protein Added: AAN79707.1 iroN siderophore salmochelin receptor IroN + Protein Added: AAN80033.1 iss increased serum survival lipoprotein Iss + Protein Added: AAN83596.1 ireA TonB-dependent siderophore receptor IreA + Protein Added: CAB14519.1 arsC thioredoxin-dependent arsenate reductase + Protein Added: AAB91079.1 copB copper-binding protein CopB + Protein Added: CAA05105.1 copP copper-binding metallochaperone CopP + Protein Added: AAB88410.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: EEZ94110.1 sdeA multidrug efflux RND transporter periplasmic adaptor subunit SdeA + Protein Added: AAO17297.1 eatA serine protease autotransporter toxin EatA + Protein Added: ADA73787.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 + Protein Added: ADA76801.1 sepA serine protease autotransporter toxin SepA + Protein Added: AAO19475.1 stx1Ad Shiga toxin Stx1d subunit A + Protein Added: AAO19476.1 stx1Bd Shiga toxin Stx1d subunit B + Protein Added: ADA79992.1 merT mercuric transport protein MerT + Protein Added: CBG87859.1 nleB type III secretion system effector arginine glycosyltransferase NleB + Protein Added: CBG89712.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: CAD66214.1 vactox vacuolating autotransporter toxin Vat + Protein Added: ADB20445.1 toxB toxin B + Protein Added: CBG36837.1 eilA HilA family transcriptional regulator EilA + Protein Added: CBG36838.1 air inverse autotransporter adhesin EaeX/Air + Protein Added: CBG37385.1 aaiC type VI secretion system protein AaiC/Hcp2 + Protein Added: CBG27762.1 aatA dispersin export ABC transporter outer membrane protein AatA + Protein Added: CBG27784.1 aafB aggregative adherence fimbria II minor subunit AafB + Protein Added: CBG27798.1 aafD aggregative adherence fimbria II chaperone AafD + Protein Added: CBG27800.1 aafA aggregative adherence fimbria II major subunit AafA + Protein Added: CBG27804.1 aggR aggregative adherence transcriptional regulator AggR + Protein Added: CBG27807.1 aap dispersin Aap + Protein Added: CBG27812.1 aar AggR-activated transcriptional regulator Aar + Protein Added: AAD12174.1 stx2Ab Shiga toxin Stx2b subunit A + Protein Added: AAO49780.1 ttgD toluene efflux RND transporter periplasmic adaptor subunit TtgD + Protein Added: AAC38390.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAC38394.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: AAC38400.1 espF type III secretion system LEE effector EspF + Protein Added: BAA24822.1 arsA arsenite efflux transporter ATPase subunit ArsA + Protein Added: AAA20885.1 astA heat-stable enterotoxin EAST1 + Protein Added: AAA23736.1 f17g F17G fimbrial adhesin + Protein Added: AAA23737.1 f17a F17A fimbrial adhesin + Protein Added: ADD58872.1 espF type III secretion system LEE effector EspF + Protein Added: ADD58881.1 eae intimin type gamma + Protein Added: ADD58883.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: EFF39147.1 norM sodium-coupled multidrug efflux MATE transporter NorM + Protein Added: AAO66617.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: BAJ04486.1 perA BFP system transcriptional regulator PerA + Protein Added: BAJ04488.1 perA BFP system transcriptional regulator PerA + Protein Added: AAC38219.1 merP mercury resistance system periplasmic binding protein MerP + Protein Added: AAC38220.1 merA mercury(II) reductase + Protein Added: AAC38221.1 merD mercury resistance co-regulator MerD + Protein Added: ADE90928.1 vactox vacuolating autotransporter toxin Vat + Protein Added: AAC38229.1 merR mercury resistance transcriptional regulator MerR + Protein Added: AAC38230.1 merB organomercurial lyase MerB + Protein Added: AAC38231.1 merT mercuric transport protein MerT + Protein Added: AAC38232.1 merP mercury resistance system periplasmic binding protein MerP + Protein Added: AAC38233.1 merC organomercurial transporter MerC + Protein Added: AAC38236.1 merE broad-spectrum mercury transporter MerE + Protein Added: ADF64798.1 ncrC Ni(II)/Co(II) efflux transporter permease subunit NcrC + Protein Added: CBK85583.1 iroN siderophore salmochelin receptor IroN + Protein Added: CBL93318.1 capU putative hexosyltransferase CapU + Protein Added: CBL93506.1 lngA type IV pilus longus major pilin + Protein Added: ADI59685.1 astA heat-stable enterotoxin EAST1 + Protein Added: ADI95409.1 ttgE multidrug efflux RND transporter permease subunit TtgE + Protein Added: ADI95411.1 ttgT efflux transport transcriptional regulator TtgT + Protein Added: AAP03990.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF + Protein Added: AAP18950.1 lpfA long polar fimbria major subunit LpfA-O113 + Protein Added: ADK23698.1 qacR multidrug-binding transcriptional regulator QacR + Protein Added: ADK73987.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAM22256.1 stx2Ad Shiga toxin Stx2d subunit A + Protein Added: AAM22257.1 stx2Bd Shiga toxin Stx2d subunit B + Protein Added: CAD56174.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF + Protein Added: CAD56186.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF + Protein Added: AAA16360.1 stx2Ab Shiga toxin Stx2b subunit A + Protein Added: AAA16361.1 stx2Bb Shiga toxin Stx2b subunit B + Protein Added: AAA16362.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: ADM83435.1 nleA type III secretion system effector NleA + Protein Added: ADN71659.1 iss increased serum survival lipoprotein Iss + Protein Added: AAP37403.1 stx2Ag Shiga toxin Stx2g subunit A + Protein Added: AAC26634.1 pet serine protease autotransporter toxin Pet + Protein Added: CBJ04488.1 cfaC CFA/I pilus usher protein CfaC + Protein Added: AAC15683.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: ADO96486.1 hmrM sodium-coupled multidrug efflux MATE transporter HmrM + Protein Added: ADP02162.1 merA mercury(II) reductase + Protein Added: CAA73506.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: ADR26561.1 iss increased serum survival lipoprotein Iss + Protein Added: ADR70747.1 copA laccase-like oxidase CopA + Protein Added: ADR70748.1 copB copper-binding protein CopB + Protein Added: BAC77251.1 sdeY multidrug efflux RND transporter permease subunit SdeY + Protein Added: ADW66881.1 arsH arsenic resistance NADPH-dependent reductase ArsH + Protein Added: AAP78989.1 ipaD type III secretion system needle tip complex protein IpaD + Protein Added: BAC78639.1 stx1Aa Shiga toxin Stx1a subunit A + Protein Added: BAC78640.1 stx1Ba Shiga toxin Stx1a subunit B + Protein Added: AAC69314.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAC69318.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: BAJ79293.1 aafA aggregative adherence fimbria II major subunit AafA + Protein Added: BAJ79295.1 aafA aggregative adherence fimbria II major subunit AafA + Protein Added: BAJ79296.1 aafA aggregative adherence fimbria II major subunit AafA + Protein Added: BAJ79297.1 aafA aggregative adherence fimbria II major subunit AafA + Protein Added: BAJ79299.1 agg5A aggregative adherence fimbria V major subunit Agg5A + Protein Added: BAJ79300.1 agg5A aggregative adherence fimbria V major subunit Agg5A + Protein Added: ADY84088.1 nreB nickel resistance MFS transporter NreB + Protein Added: AAC24352.1 ehxA enterohemolysin + Protein Added: ADZ45128.1 ehxA enterohemolysin + Protein Added: AAP88295.1 copA laccase-like oxidase CopA + Protein Added: AEC46567.1 copA laccase-like oxidase CopA + Protein Added: AEC46568.1 copB copper-binding protein CopB + Protein Added: AAC38671.1 ttgB multidrug efflux RND transporter permease subunit TtgB + Protein Added: BAA31774.1 ehxA enterohemolysin + Protein Added: BAA31815.1 toxB toxin B + Protein Added: BAA31832.1 katP catalase/peroxidase KatP + Protein Added: BAA31836.1 espP serine protease autotransporter EspP + Protein Added: AAQ17236.1 mco multi-copper oxidase Mco + Protein Added: AAQ17546.1 stx2Ae Shiga toxin Stx2e subunit A + Protein Added: CAA74174.1 espB type III secretion system LEE translocon pore-forming subunit EspB + Protein Added: AEG95593.1 iroN siderophore salmochelin receptor IroN + Protein Added: AAQ20107.1 cfaC CFA/I pilus usher protein CfaC + Protein Added: AEK01061.1 iroN siderophore salmochelin receptor IroN + Protein Added: AAC31499.1 espB type III secretion system LEE translocon pore-forming subunit EspB + Protein Added: AAY90617.2 emhA efflux RND transporter periplasmic adaptor subunit EmhA + Protein Added: CAA12346.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: CAA12348.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: AEM17342.1 cdtB cytolethal distending toxin nuclease subunit CdtB + Protein Added: AAC33154.1 lngA type IV pilus longus major pilin + Protein Added: AEQ14997.1 eilA HilA family transcriptional regulator EilA + Protein Added: AEQ15694.1 capU putative hexosyltransferase CapU + Protein Added: AAC33908.1 merC organomercurial transporter MerC + Protein Added: CCE21264.1 agg3A aggregative adherence fimbria 3 major subunit Agg3A + Protein Added: EHE72460.1 pmrA multidrug efflux MFS transporter PmrA + Protein Added: EHF16244.1 aatA dispersin export ABC transporter outer membrane protein AatA + Protein Added: EHF16297.1 aggB aggregative adherence fimbria I minor subunit AggB + Protein Added: EHF16298.1 aggA aggregative adherence fimbria I major subunit AggA + Protein Added: AET11941.1 nleA type III secretion system effector NleA + Protein Added: AET11995.1 nleA type III secretion system effector NleA + Protein Added: AET12008.1 nleA type III secretion system effector NleA + Protein Added: BAL46940.1 eae intimin type alpha + Protein Added: BAL46941.1 eae intimin type epsilon + Protein Added: BAL47132.1 eae intimin type epsilon + Protein Added: BAL47176.1 eae intimin type rho + Protein Added: BAL47179.1 eae intimin type epsilon + Protein Added: BAL47181.1 eae intimin type alpha + Protein Added: AEZ42789.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AEZ43710.1 nleA type III secretion system effector NleA + Protein Added: AAQ92182.1 emhC efflux RND transporter outer membrane subunit EmhC + Protein Added: CAA77068.1 aggA aggregative adherence fimbria I major subunit AggA + Protein Added: AAR02190.1 aggA aggregative adherence fimbria I major subunit AggA + Protein Added: BAL72684.1 cdtB cytolethal distending toxin nuclease subunit CdtB + Protein Added: BAL72697.1 cdtB cytolethal distending toxin nuclease subunit CdtB + Protein Added: AAR12207.1 cdtB cytolethal distending toxin type III/V nuclease subunit CdtB + Protein Added: AAC69584.1 ybtQ yersiniabactin ABC transporter ATP-binding/permease protein YbtQ + Protein Added: AAR13270.1 iroN siderophore salmochelin receptor IroN + Protein Added: AFH14350.1 faeG F4 fimbrial adhesin subunit FaeG + Protein Added: CAD87828.1 sta1 heat-stable enterotoxin ST-I group a + Protein Added: BAA34299.1 mexX multidrug efflux RND transporter periplasmic adaptor subunit MexX + Protein Added: AFK88558.1 auto-sat serine protease autotransporter toxin Sat + Protein Added: AFM31243.1 tccP Tir-cytoskeleton coupling protein TccP2 + Protein Added: AFM70729.1 copA copper-translocating P-type ATPase CopA + Protein Added: AFM70730.1 copB copper/silver-translocating P-type ATPase CopB + Protein Added: AAC82360.1 espB type III secretion system LEE translocon pore-forming subunit EspB + Protein Added: AAR82963.1 nirA nickel resistance membrane nickel efflux protein NirA + Protein Added: AAR82964.1 nirB nickel-sensing transcriptional repressor NirB + Protein Added: AAR82966.1 nirD nickel resistance OB fold protein NirD + Protein Added: AFQ65076.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF + Protein Added: CAA50007.1 cnf1 cytotoxic necrotizing factor CNF1 + Protein Added: CAA12345.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: CAA12350.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: CAA12351.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: AFS59871.1 sepA serine protease autotransporter toxin SepA + Protein Added: AFS85685.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF + Protein Added: AAC99337.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: CAA21388.1 ybtP yersiniabactin ABC transporter ATP-binding/permease protein YbtP + Protein Added: BAA36431.1 merR mercury resistance transcriptional regulator MerR + Protein Added: BAA36433.1 merD mercury resistance co-regulator MerD + Protein Added: CAA40744.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF + Protein Added: CAA23532.1 ltcA heat-labile enterotoxin LT subunit A + Protein Added: CAA32535.1 fim41a fimbrial adhesin F41 protein Fim41a + Protein Added: AAD05936.1 copP copper-binding metallochaperone CopP + Protein Added: AAS07580.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: AAS07581.1 stx2Bc Shiga toxin Stx2c subunit B + Protein Added: AAS07582.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: AAS07586.1 stx2Ad Shiga toxin Stx2d subunit A + Protein Added: AAS07588.1 stx2Ad Shiga toxin Stx2d subunit A + Protein Added: AAS07589.1 stx2Bd Shiga toxin Stx2d subunit B + Protein Added: AAS07590.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: AAS07596.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: AAS07600.1 stx2Aa Shiga toxin Stx2a subunit A + Protein Added: AAS07606.1 stx2Aa Shiga toxin Stx2a subunit A + Protein Added: AAD11743.1 silE silver-binding protein SilE + Protein Added: AAD11746.1 silC Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC + Protein Added: AAD11748.1 silB Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB + Protein Added: AAD11749.1 silA Cu(+)/Ag(+) efflux RND transporter permease subunit SilA + Protein Added: AAD11750.1 silP Ag(+)-translocating P-type ATPase SilP + Protein Added: AFX83959.1 subA subtilase AB5 cytotoxin subunit A + Protein Added: AAS21297.1 tbtR tribuytltin resistance regulator TbtR + Protein Added: CAA43585.1 stx2Ad Shiga toxin Stx2d subunit A + Protein Added: AAD15663.1 tbtA multidrug efflux RND transporter periplasmic adaptor subunit TbtA + Protein Added: AAD15664.1 tbtB multidrug efflux RND transporter permease subunit TbtB + Protein Added: AAD15665.1 tbtM multidrug efflux RND transporter outer membrane channel subunit TbtM + Protein Added: AAD17509.1 f17a F17A fimbrial adhesin + Protein Added: AAD17510.1 f17a F17A fimbrial adhesin + Protein Added: AAD17511.1 f17a F17A fimbrial adhesin + Protein Added: AAD17513.1 f17g F17G fimbrial adhesin + Protein Added: AAD17514.1 f17g F17G fimbrial adhesin + Protein Added: AAD17515.1 f17g F17G fimbrial adhesin + Protein Added: AAA18786.1 cdtB cytolethal distending toxin type II nuclease subunit CdtB + Protein Added: CAA77320.1 merR mercury resistance transcriptional regulator MerR + Protein Added: CAA77324.1 merD mercury resistance co-regulator MerD + Protein Added: CAA77325.1 merE broad-spectrum mercury transporter MerE + Protein Added: CAA81047.1 mtrR multidrug efflux system transcriptional repressor MtrR + Protein Added: AAA74436.1 mexA multidrug efflux RND transporter periplasmic adaptor subunit MexA + Protein Added: AGC14252.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF + Protein Added: AAS47019.1 nleC type III secretion system effector zinc metalloprotease NleC + Protein Added: AGC85979.1 iss increased serum survival lipoprotein Iss + Protein Added: CCG33322.1 iroN siderophore salmochelin receptor IroN + Protein Added: AAS50165.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF + Protein Added: AAO18187.2 sdeB multidrug efflux RND transporter permease subunit SdeB + Protein Added: AAA98221.1 merR mercury resistance transcriptional regulator MerR + Protein Added: AAS76847.1 fedA F18 fimbrial major subunit FedA + Protein Added: AAD25959.1 merR2 mercury resistance transcriptional regulator MerR2 + Protein Added: AAA98245.1 merA mercury(II) reductase + Protein Added: AAD27810.1 aafC aggregative adherence fimbria II usher protein AafC + Protein Added: AAA24698.1 tsh temperature-sensitive protease autotransporter hemagglutinin Tsh + Protein Added: CAE82650.1 faeG F4 fimbrial adhesin subunit FaeG + Protein Added: CAE82653.1 faeG F4 fimbrial adhesin subunit FaeG + Protein Added: CAE82670.1 faeG F4 fimbrial adhesin subunit FaeG + Protein Added: AAD28079.1 hlyE hemolysin HlyE + Protein Added: CAA83535.1 aggR aggregative adherence transcriptional regulator AggR + Protein Added: EMS03085.1 aggA aggregative adherence fimbria I major subunit AggA + Protein Added: CAE55775.1 auto-sat serine protease autotransporter toxin Sat + Protein Added: AAT36311.1 rpeA serine protease autotransporter colonization factor RpeA + Protein Added: BAA77749.1 stx2Ab Shiga toxin Stx2b subunit A + Protein Added: BAA77750.1 stx2Bb Shiga toxin Stx2b subunit B + Protein Added: BAA77751.1 stx2Ab Shiga toxin Stx2b subunit A + Protein Added: CAA46767.1 stx2Ab Shiga toxin Stx2b subunit A + Protein Added: CAA46768.1 stx2Bb Shiga toxin Stx2b subunit B + Protein Added: CAA77936.1 emrE multidrug efflux SMR transporter EmrE + Protein Added: AAT65972.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: AAT66000.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: AAT66010.1 stx2Aa Shiga toxin Stx2a subunit A + Protein Added: AAT66011.1 stx2Ba Shiga toxin Stx2a subunit B + Protein Added: AAT66012.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: AGL46515.1 merF mercury resistance system transport protein MerF + Protein Added: AAT68784.1 subB subtilase AB5 cytotoxin subunit B + Protein Added: AAT68785.1 subA subtilase AB5 cytotoxin subunit A + Protein Added: AAT76975.1 lpfA long polar fimbria major subunit LpfA-O113 + Protein Added: AAD39553.1 ttgA toluene efflux RND transporter periplasmic adaptor subunit TtgA + Protein Added: AAU01878.1 sepA serine protease autotransporter toxin SepA + Protein Added: AAN38824.2 adeE multidrug efflux RND transporter permease subunit AdeE + Protein Added: AAU10477.1 adeD multidrug efflux RND transporter periplasmic adaptor subunit AdeD + Protein Added: AAU88208.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: AAU88264.1 cdtB cytolethal distending toxin nuclease subunit CdtB + Protein Added: AAA57451.1 aggD aggregative adherence fimbria I chaperone AggD + Protein Added: AAA57452.1 aggC aggregative adherence fimbria I usher protein AggC + Protein Added: AAA57453.1 aggB aggregative adherence fimbria I minor subunit AggB + Protein Added: AAA57454.1 aggA aggregative adherence fimbria I major subunit AggA + Protein Added: CAA85366.1 stx1Aa Shiga toxin Stx1a subunit A + Protein Added: CAA85368.1 stx1Aa Shiga toxin Stx1a subunit A + Protein Added: CAA85370.1 stx1Ac Shiga toxin Stx1c subunit A + Protein Added: CAA85371.1 stx1Bc Shiga toxin Stx1c subunit B + Protein Added: EQX61716.1 aggA aggregative adherence fimbria I major subunit AggA + Protein Added: AAU95470.1 nleB type III secretion system effector arginine glycosyltransferase NleB + Protein Added: AAU95768.1 mepA multidrug efflux MATE transporter MepA + Protein Added: CAG17536.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: CAG17541.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: AAD43578.1 astA heat-stable enterotoxin EAST1 + Protein Added: AAD43579.1 astA heat-stable enterotoxin EAST1 + Protein Added: CAA85780.1 stx2Aa Shiga toxin Stx2a subunit A + Protein Added: AAA80193.1 mtrC multidrug efflux RND transporter periplasmic adaptor subunit MtrC + Protein Added: AAD44693.1 mtrA efflux transporter MtrCDE transcriptional activator MtrA + Protein Added: AAD47284.1 terZ tellurium resistance-associated protein TerZ + Protein Added: AAW38464.1 lmrS multidrug efflux MFS transporter LmrS + Protein Added: CAI43856.1 espF type III secretion system LEE effector EspF + Protein Added: CAI43860.1 espB type III secretion system LEE translocon pore-forming subunit EspB + Protein Added: CAI43862.1 espA type III secretion system LEE translocon filament protein EspA + Protein Added: CAI43865.1 eae intimin type epsilon + Protein Added: CAI43867.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAD54074.1 farB fatty acid resistance MFS efflux transporter permease subunit FarB + Protein Added: BAA84838.1 bfpA bundle-forming pilus major subunit BfpA + Protein Added: BAA84859.1 perA BFP system transcriptional regulator PerA + Protein Added: AAT35241.2 tsh temperature-sensitive protease autotransporter hemagglutinin Tsh + Protein Added: AAF03351.1 espF type III secretion system LEE effector EspF + Protein Added: AHW84565.1 aaiC type VI secretion system protein AaiC/Hcp2 + Protein Added: AHW84567.1 aaiC type VI secretion system protein AaiC/Hcp2 + Protein Added: AAX47728.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAX47729.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAX47730.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAX47731.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: CAA58525.1 pcoA multicopper oxidase PcoA + Protein Added: CAA58526.1 pcoB copper-binding protein PcoB + Protein Added: CAA58527.1 pcoC copper resistance system metallochaperone PcoC + Protein Added: CAA58528.1 pcoD copper resistance inner membrane protein PcoD + Protein Added: CAA58529.1 pcoR copper response regulator transcription factor PcoR + Protein Added: CAA58530.1 pcoS copper resistance membrane spanning protein PcoS + Protein Added: CAA58532.1 pcoE copper resistance system metallochaperone PcoE + Protein Added: AAX63244.1 fedF F18 fimbrial adhesin subunit FedF + Protein Added: AAX63245.1 fedF F18 fimbrial adhesin subunit FedF + Protein Added: AAX63259.1 fedF F18 fimbrial adhesin subunit FedF + Protein Added: AAX63270.1 fedF F18 fimbrial adhesin subunit FedF + Protein Added: AAY25390.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAY25394.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAY25395.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAF14522.1 mexX multidrug efflux RND transporter periplasmic adaptor subunit MexX + Protein Added: CAI91198.1 stx2Ag Shiga toxin Stx2g subunit A + Protein Added: AAF16681.1 srpS solvent efflux transporter transcriptional repressor SrpS + Protein Added: AAF16682.1 srpR solvent efflux transporter antirepressor SrpR + Protein Added: CAA54115.1 nfaE Dr family non-fimbrial adhesin I chaperone NfaE + Protein Added: AAF23359.1 eae intimin type epsilon + Protein Added: CAB64953.1 stx2Af Shiga toxin Stx2f subunit A + Protein Added: AAY63864.1 stx2Ad Shiga toxin Stx2d subunit A + Protein Added: AAY63865.1 stx2Bd Shiga toxin Stx2d subunit B + Protein Added: CDY80020.1 hsp20 small heat shock protein sHSP20 + Protein Added: AAY90615.1 emhC efflux RND transporter outer membrane subunit EmhC + Protein Added: KGL71342.1 silF Ag(+)/Cu(+) efflux RND transporter periplasmic metallochaperone SilF + Protein Added: AAF40764.1 farB fatty acid resistance MFS efflux transporter permease subunit FarB + Protein Added: AAF42063.1 mtrC multidrug efflux RND transporter periplasmic adaptor subunit MtrC + Protein Added: AAB26855.2 nfaE Dr family non-fimbrial adhesin I chaperone NfaE + Protein Added: CAB82448.1 cnrY nickel resistance system anti-sigma factor CnrY + Protein Added: AAZ76497.1 ehxA enterohemolysin + Protein Added: AAZ76514.1 espP serine protease autotransporter EspP + Protein Added: AAZ76524.1 subA subtilase AB5 cytotoxin subunit A + Protein Added: AAZ87985.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 + Protein Added: AAZ88030.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 + Protein Added: AAZ89804.1 sigA serine protease autotransporter toxin SigA + Protein Added: AAZ91108.1 ipaD type III secretion system needle tip complex protein IpaD + Protein Added: ABA25986.1 merF mercury resistance system transport protein MerF + Protein Added: AAX22079.2 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF + Protein Added: AAA65102.1 nccX periplasmic metal sensor NccX + Protein Added: AAA65103.1 nccH nickel/cobalt/cadmium resistance ECF sigma factor NccH + Protein Added: ABB16332.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: ABB36584.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: ABB36586.1 stx2Ad Shiga toxin Stx2d subunit A + Protein Added: ABB61187.1 iroN siderophore salmochelin receptor IroN + Protein Added: ABB62096.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 + Protein Added: ABB62098.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 + Protein Added: ABB64677.1 ipaD type III secretion system needle tip complex protein IpaD + Protein Added: ABB65884.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 + Protein Added: ABB66229.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 + Protein Added: ABB68924.1 virF AraC family invasion system transcriptional regulator VirF + Protein Added: KLB41245.1 copL transcriptional regulator CopL + Protein Added: CAI79539.1 eatA serine protease autotransporter toxin EatA + Protein Added: CAJ44959.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF + Protein Added: CAB77169.2 stx2Ae Shiga toxin Stx2e subunit A + Protein Added: CAB94149.1 stx2Ba Shiga toxin Stx2a subunit B + Protein Added: AAC34727.1 faeG F4 fimbrial adhesin subunit FaeG + Protein Added: BAA96815.1 tir type III secretion system LEE translocated intimin receptor Tir + Protein Added: AAA69514.1 f17g F17G fimbrial adhesin + Protein Added: CAA88252.1 sepA serine protease autotransporter toxin SepA + Protein Added: BAE79899.1 smfY multidrug efflux MFS transporter SmfY + Protein Added: ABE06598.1 sfaS S-fimbrial adhesin minor subunit SfaS + Protein Added: ABE10324.1 cnf1 cytotoxic necrotizing factor CNF1 + Protein Added: CAJ34994.1 bfpA bundle-forming pilus major subunit BfpA + Protein Added: ABF13034.1 merD mercury resistance co-regulator MerD + Protein Added: ABF13067.1 cnrC nickel efflux RND transporter outer membrane subunit CnrC + Protein Added: ABF13069.1 cnrA nickel efflux RND transporter permease subunit CnrA + Protein Added: ABF13070.1 cnrT nickel diffusion facilitator CnrT + Protein Added: ABF14406.1 ncrA Metal Resistance + Protein Added: ABF14407.1 ncrB nickel-sensing transcriptional repressor NcrB + Protein Added: CAK02719.1 cnf1 cytotoxic necrotizing factor CNF1 + Protein Added: CAA90630.1 stx2Aa Shiga toxin Stx2a subunit A + Protein Added: BAT41861.1 eae intimin type alpha + Protein Added: CAK15125.1 mexE MexE family multidrug efflux RND transporter periplasmic adaptor subunit + Protein Added: AAG01033.1 stx2Ac Shiga toxin Stx2c subunit A + Protein Added: AAB59153.1 cadC Cd(II)/Pb(II)/Zn(II)-sensing metalloregulatory transcriptional repressor CadC + Protein Added: ABF61434.1 ncrA Metal Resistance + Protein Added: ABF61435.1 ncrB nickel-sensing transcriptional repressor NcrB + Protein Added: ABF61437.1 ncrY nickel resistance OB fold protein NcrY + Protein Added: AAG05881.1 mexE MexE family multidrug efflux RND transporter periplasmic adaptor subunit + Protein Added: AAG10695.1 perA BFP system transcriptional regulator PerA + Protein Added: WP_000697899.1 pmrA pmrA + Protein Added: WP_097509477.1 acrB acrB + +- AMRFinder HMM library Changes: + Prev. Release: 574 + This Release: 610 + Removed: 2 + Added: 38 + Changed: 572 + HMM Removed: NF000478.2 linco_LnuE + HMM Removed: NF012180.1 tet_MFS_43 + HMM Added: NF000131.1 MATE_multi_MepA + HMM Added: NF000249.1 MexE + HMM Added: NF000252.1 MexX + HMM Added: NF000263.1 MATE_multi_NorM + HMM Added: NF000282.2 RND_permease_1 + HMM Added: NF000314.1 adeB + HMM Added: NF000315.1 adeC-adeK-oprM + HMM Added: NF000336.1 emrE + HMM Added: NF007842.1 PRK10555.1 + HMM Added: NF010310.2 PRK13747.1 + HMM Added: NF010315.0 PRK13752.1 + HMM Added: NF011706.2 PRK15127.1 + HMM Added: NF028537.1 P_eth_NH2_trans + HMM Added: NF033086.2 penta_rpt_Qnr + HMM Added: NF033134.0 cmlA_floR + HMM Added: NF033142.1 efflux_OM_AdeC + HMM Added: NF033143.1 efflux_OM_AdeK + HMM Added: NF033555.1 lyase_MerB + HMM Added: NF033560.1 merT_RC607 + HMM Added: NF033565.0 trans_MerF + HMM Added: NF033627.3 intimin_all + HMM Added: NF033637.1 transloc_TIR + HMM Added: NF033639.1 intimin_alpha + HMM Added: NF033643.1 EspJ_gen + HMM Added: NF033646.1 toxin_EAST1 + HMM Added: NF033651.1 cyto_nec_fctrs + HMM Added: NF033658.1 Shiga_Stx1A + HMM Added: NF033659.0 Shiga_Stx1B + HMM Added: NF033660.0 Shiga_Stx2B + HMM Added: NF033661.1 Shiga_Stx2A + HMM Added: NF033727.1 chaperon_ArsD + HMM Added: NF033781.1 chaper_CopP + HMM Added: NF033783.1 coreg_MerD + HMM Added: NF033784.1 transport_merC + HMM Added: NF033786.1 phenyl_MerG + HMM Added: NF033834.1 RND_adapt_MexA + HMM Added: TIGR02052.1 TIGR02052 + HMM Added: TIGR02053.1 TIGR02053 +--------------------------------------------------------------------- +Changes included in 2019-04-29.1 +--------------------------------------------------------------------- + +Summary: In addition to the usual addition of 134 new genes and alleles +community feedback led to the renaming of a few dfr genes. The family +heirarchy file (fam.tab) was cleaned up by removing a number of superfluous +entries. + +Changes included in 2019-04-29.1 +- Protein changes: + Prev. Release: 4810 + This Release: 4942 + Removed: 1 + Added: 134 + Modified: 3 + Protein Removed: WP_109545040.1 chrB + Protein Added: WP_000054744.1 satA_Ba + Protein Added: WP_001211209.1 blaADC-140 + Protein Added: WP_001211210.1 blaADC-185 + Protein Added: WP_001211214.1 blaADC-144 + Protein Added: WP_001211215.1 blaADC-115 + Protein Added: WP_001572373.1 mcr-9.1 + Protein Added: WP_002126587.1 blaADC-120 + Protein Added: WP_002157727.1 blaADC-117 + Protein Added: WP_003112187.1 blaADC-191 + Protein Added: WP_003242546.1 satA_Bs + Protein Added: WP_004643536.1 blaADC-128 + Protein Added: WP_004700205.1 blaADC-133 + Protein Added: WP_004707701.1 blaADC-131 + Protein Added: WP_004712857.1 blaADC-119 + Protein Added: WP_004790939.1 blaADC-135 + Protein Added: WP_004840559.1 blaADC-123 + Protein Added: WP_004886093.1 blaADC-130 + Protein Added: WP_005039111.1 blaADC-129 + Protein Added: WP_005046018.1 blaADC-127 + Protein Added: WP_005068074.1 blaADC-132 + Protein Added: WP_005109685.1 blaADC-121 + Protein Added: WP_005123276.1 blaADC-122 + Protein Added: WP_005131186.1 blaADC-125 + Protein Added: WP_005307218.1 blaADC-134 + Protein Added: WP_005404206.1 blaOXA-813 + Protein Added: WP_005405613.1 blaOXA-814 + Protein Added: WP_013197184.1 blaADC-193 + Protein Added: WP_014207272.1 blaADC-149 + Protein Added: WP_016137488.1 blaADC-136 + Protein Added: WP_016140427.1 blaADC-137 + Protein Added: WP_016146025.1 blaADC-138 + Protein Added: WP_017386568.1 blaADC-150 + Protein Added: WP_017778762.1 mcr-3.27 + Protein Added: WP_017816757.1 blaADC-116 + Protein Added: WP_026382828.1 blaOXA-114i + Protein Added: WP_026444036.1 blaOXA-816 + Protein Added: WP_032039838.1 blaADC-139 + Protein Added: WP_032053762.1 blaOXA-819 + Protein Added: WP_032057042.1 blaOXA-820 + Protein Added: WP_032062810.1 blaADC-141 + Protein Added: WP_032625176.1 blaACT-66 + Protein Added: WP_033502167.1 blaADC-143 + Protein Added: WP_034670108.1 blaOXA-818 + Protein Added: WP_034688190.1 blaOXA-812 + Protein Added: WP_036299413.1 sulR + Protein Added: WP_039246976.1 blaADC-148 + Protein Added: WP_039258389.1 blaADC-146 + Protein Added: WP_039270258.1 blaADC-145 + Protein Added: WP_044718369.1 blaADC-147 + Protein Added: WP_047726486.1 blaACT-65 + Protein Added: WP_053498400.1 blaOXA-114h + Protein Added: WP_054437016.1 blaOXA-114j + Protein Added: WP_054471662.1 blaOXA-114m + Protein Added: WP_054500785.1 blaOXA-789 + Protein Added: WP_054517040.1 blaOXA-114l + Protein Added: WP_057061999.1 blaOXA-821 + Protein Added: WP_059247009.1 blaADC-184 + Protein Added: WP_063099318.1 blaADC-151 + Protein Added: WP_063147148.1 blaACT-67 + Protein Added: WP_072292271.1 blaADC-186 + Protein Added: WP_075040046.1 blaOXA-817 + Protein Added: WP_076412384.1 blaOXA-114p + Protein Added: WP_099595307.1 dfrA35 + Protein Added: WP_103663397.1 sulX + Protein Added: WP_106743337.1 mcr-1.18 + Protein Added: WP_109545052.1 mcr-1.14 + Protein Added: WP_110612827.1 blaOXA-796 + Protein Added: WP_111280830.1 blaOXA-815 + Protein Added: WP_115470049.1 blaKPC-40 + Protein Added: WP_117664257.1 cfxA6 + Protein Added: WP_125052776.1 blaADC-114 + Protein Added: WP_136512051.1 blaACT-68 + Protein Added: WP_136512052.1 blaADC-109 + Protein Added: WP_136512053.1 blaADC-110 + Protein Added: WP_136512054.1 blaADC-112 + Protein Added: WP_136512055.1 blaADC-113 + Protein Added: WP_136512056.1 blaADC-187 + Protein Added: WP_136512057.1 blaADC-188 + Protein Added: WP_136512058.1 blaADC-189 + Protein Added: WP_136512059.1 blaADC-190 + Protein Added: WP_136512060.1 blaADC-192 + Protein Added: WP_136512061.1 blaADC-24 + Protein Added: WP_136512062.1 blaADC-65 + Protein Added: WP_136512063.1 blaADC-66 + Protein Added: WP_136512064.1 blaCTX-M-225 + Protein Added: WP_136512065.1 blaCTX-M-226 + Protein Added: WP_136512066.1 blaFRI-7 + Protein Added: WP_136512067.1 blaIMI-18 + Protein Added: WP_136512068.1 blaIMP-39 + Protein Added: WP_136512069.1 blaIMP-46 + Protein Added: WP_136512070.1 blaKPC-42 + Protein Added: WP_136512071.1 blaKPC-43 + Protein Added: WP_136512072.1 blaNDM-28 + Protein Added: WP_136512073.1 blaOXA-114k + Protein Added: WP_136512074.1 blaOXA-114n + Protein Added: WP_136512075.1 blaOXA-114q + Protein Added: WP_136512076.1 blaOXA-114r + Protein Added: WP_136512077.1 blaOXA-114s + Protein Added: WP_136512078.1 blaOXA-114t + Protein Added: WP_136512079.1 blaOXA-114u + Protein Added: WP_136512080.1 blaOXA-114v + Protein Added: WP_136512081.1 blaOXA-114w + Protein Added: WP_136512082.1 blaOXA-114x + Protein Added: WP_136512083.1 blaOXA-787 + Protein Added: WP_136512084.1 blaOXA-788 + Protein Added: WP_136512085.1 blaOXA-793 + Protein Added: WP_136512086.1 blaOXA-794 + Protein Added: WP_136512087.1 blaOXA-795 + Protein Added: WP_136512088.1 blaOXA-797 + Protein Added: WP_136512089.1 blaOXA-798 + Protein Added: WP_136512090.1 blaOXA-799 + Protein Added: WP_136512091.1 blaOXA-800 + Protein Added: WP_136512092.1 blaOXA-801 + Protein Added: WP_136512093.1 blaOXA-802 + Protein Added: WP_136512094.1 blaOXA-803 + Protein Added: WP_136512095.1 blaOXA-804 + Protein Added: WP_136512096.1 blaOXA-805 + Protein Added: WP_136512097.1 blaOXA-806 + Protein Added: WP_136512098.1 blaOXA-807 + Protein Added: WP_136512099.1 blaOXA-808 + Protein Added: WP_136512100.1 blaOXA-809 + Protein Added: WP_136512101.1 blaOXA-810 + Protein Added: WP_136512102.1 blaOXA-811 + Protein Added: WP_136512103.1 blaOXA-823 + Protein Added: WP_136512104.1 blaOXA-824 + Protein Added: WP_136512105.1 blaPER-13 + Protein Added: WP_136512106.1 blaVIM-48 + Protein Added: WP_136512107.1 blaVIM-55 + Protein Added: WP_136512108.1 blaVIM-63 + Protein Added: WP_136512109.1 blaVIM-66 + Protein Added: WP_136512110.1 mcr-1.16 + Protein Added: WP_136512111.1 mcr-1.17 + Protein Added: WP_136512112.1 mcr-3.29 + Protein Modified: WP_001031075.1 dfr18 updated to WP_001031075.1 dfrA18 + Protein Modified: WP_032490189.1 dfrA18 updated to WP_032490189.1 dfrA19 + Protein Modified: WP_063843245.1 chrB updated to WP_063843245.1 chrB_rRNA_meth +- AMR HMM library Changes: + Prev. Release: 571 + This Release: 574 + Removed: 0 + Added: 3 + Changed: 571 + HMM Added: NF033818.0 blaOXA-114_like + HMM Added: NF033836.1 polymyxin_MCR9 + HMM Added: NF033851.1 trim_DfrA35 + HMM Modified: NF000039.1 trim_Dfr18 renamed to NF000039.1 trim_DfrA18 + HMM Modified: NF000041.1 trim_DfrA18_A19 renamed to NF000041.1 trim_DfrA19 + HMM Modified: NF000422.2 blaPDC updated to NF000422.6 blaPDC +- Protein family changes: + Prev. Release: 1177 + This Release: 1119 + Removed: 68 + Added: 10 + Modified: 4 + Family Removed: - PORIN + Family Removed: - aac(1) + Family Removed: - aac(3')-IIe + Family Removed: - aac(3)-Ie + Family Removed: - aac(3)-VI + Family Removed: - aac(3)-Vb + Family Removed: - aac(6')-Ib8 + Family Removed: - aacA44 + Family Removed: - aadA1bt + Family Removed: - aadA1r + Family Removed: - aadA24 + Family Removed: - ampC_Eae + Family Removed: - ampH + Family Removed: - ampS + Family Removed: - ant(3'')(9) + Family Removed: - ant(3'')-Ii + Family Removed: - aph(3')-Ic + Family Removed: - arr-Cb + Family Removed: - blaCMG + Family Removed: - blaKLUG + Family Removed: - blaLMB + Family Removed: - blaMSI-OXA + Family Removed: - blaOXA_missing + Family Removed: - blaPNGM + Family Removed: - blaZEG + Family Removed: - blmS + Family Removed: - catA12 + Family Removed: - ccrA + Family Removed: NF000488.1 chrB + Family Removed: - cml + Family Removed: - cmlA7 + Family Removed: - cmlA9 + Family Removed: NF000039.1 dfr18 + Family Removed: NF000041.1 dfrA18_dfrA19 + Family Removed: - dfrA1_var + Family Removed: - dfrA29 + Family Removed: - dfrA33 + Family Removed: - dfrB7 + Family Removed: - flo + Family Removed: - mef(E) + Family Removed: - mef(G) + Family Removed: - mef(I) + Family Removed: - mph(D) + Family Removed: - nimF + Family Removed: - nimH + Family Removed: - omp35 + Family Removed: - ompE35 + Family Removed: - otr(C) + Family Removed: - penA + Family Removed: - sat2A + Family Removed: - sat3A + Family Removed: - spc + Family Removed: - sul1delta + Family Removed: - vanH-Ac2 + Family Removed: - vanH-F + Family Removed: - vanR-Pt + Family Removed: - vanR-Pt2 + Family Removed: - vanS-I + Family Removed: - vanSc + Family Removed: - vanTc4 + Family Removed: - vanX-Ac2 + Family Removed: - vanX-F + Family Removed: - vanX-Pt2 + Family Removed: - vanY-40021673 + Family Removed: - vanY-D4 + Family Removed: - vanY-D5 + Family Removed: - vanY-M + Family Removed: - vanY-Pt2 + Family Added: NF033818.0 blaOXA-114_like + Family Added: NF033851.1 dfrA35 + Family Added: NF033124.1 estX + Family Added: NF033836.1 mcr-9 + Family Added: - satA_Bs + Family Added: - sulR + Family Added: - sulX + Family Changed: NF000422.2 blaPDC updated to NF000422.6 blaPDC + Family Changed: NF000488.1 chrB renamed to chrB_rRNA_meth + Family Changed: NF000039.1 dfr18 renamed to dfrA18 + Family Changed: NF000041.1 dfrA18_dfrA19 renamed to dfrA19 +--------------------------------------------------------------------- +Changes included in 2019-02-08.1 +--------------------------------------------------------------------- + +Two incorrectly assigned proteins were accidentally released. They are not +AMR proteins and should not have been released. This release simply removes +them and is otherwise unchanged. + +- Protein changes: + Prev. Release: 4812 + This Release: 4810 + Removed: 2 + Added: 0 + Changed: 4810 + Protein Removed: WP_000122253.1 sat + Protein Removed: WP_001045652.1 sat +--------------------------------------------------------------------- +Changes included in 2019-02-04.1 +--------------------------------------------------------------------- +- Protein name changes: + "inhibitor-resistant" was added to the names of: + blaKPC-8 + blaKPC-30 + blaKPC-31 + blaKPC-32 + blaKPC-33 +- Protein changes: + Prev. Release: 4730 + This Release: 4812 + Removed: 0 + Added: 82 + Protein modified: WP_063855700.1 tet(35) replaced with WP_005480402.1 + Protein Added: WP_000122253.1 sat + Protein Added: WP_001045652.1 sat + Protein Added: WP_002415638.1 poxtA + Protein Added: WP_003234144.1 vmlR + Protein Added: WP_029728367.1 blaB + Protein Added: WP_044103626.1 blaVEB-21 + Protein Added: WP_046693238.1 blaADC-181 + Protein Added: WP_049637206.1 blaOXA-780 + Protein Added: WP_057691114.1 blaADC-182 + Protein Added: WP_058492019.1 vanI + Protein Added: WP_065980086.1 blaOXA-784 + Protein Added: WP_069953510.1 blaAFM-1 + Protein Added: WP_069996660.1 mecC3 + Protein Added: WP_071223118.1 taeA + Protein Added: WP_087343787.1 ant(6)-Ic + Protein Added: WP_087344360.1 blaBBI + Protein Added: WP_087344902.1 catV + Protein Added: WP_087346196.1 ant(4')-Ic + Protein Added: WP_087347987.1 rphC + Protein Added: WP_087348261.1 rphD + Protein Added: WP_087349244.1 mphJ + Protein Added: WP_087349651.1 aac(6')-35 + Protein Added: WP_114225343.1 blaOXA-739 + Protein Added: WP_123002100.1 blaGES-40 + Protein Added: WP_123002101.1 blaKPC-38 + Protein Added: WP_123002102.1 blaNDM-27 + Protein Added: WP_123002103.1 blaVIM-61 + Protein Added: WP_126205827.1 blaOXA-785 + Protein Added: WP_127728991.1 blaFRI-6 + Protein Added: WP_128268231.1 mecC2 + Protein Added: WP_128268232.1 blaADC-183 + Protein Added: WP_128268233.1 blaCARB-50 + Protein Added: WP_128268234.1 blaCFE-2 + Protein Added: WP_128268235.1 blaCTX-M-215 + Protein Added: WP_128268236.1 blaDHA-28 + Protein Added: WP_128268237.1 blaKPC-39 + Protein Added: WP_128268238.1 blaOXA-738 + Protein Added: WP_128268239.1 blaOXA-740 + Protein Added: WP_128268240.1 blaOXA-741 + Protein Added: WP_128268241.1 blaOXA-742 + Protein Added: WP_128268242.1 blaOXA-743 + Protein Added: WP_128268243.1 blaOXA-744 + Protein Added: WP_128268244.1 blaOXA-745 + Protein Added: WP_128268245.1 blaOXA-746 + Protein Added: WP_128268246.1 blaOXA-747 + Protein Added: WP_128268247.1 blaOXA-748 + Protein Added: WP_128268248.1 blaOXA-749 + Protein Added: WP_128268249.1 blaOXA-750 + Protein Added: WP_128268250.1 blaOXA-751 + Protein Added: WP_128268251.1 blaOXA-752 + Protein Added: WP_128268252.1 blaOXA-753 + Protein Added: WP_128268253.1 blaOXA-754 + Protein Added: WP_128268254.1 blaOXA-755 + Protein Added: WP_128268255.1 blaOXA-756 + Protein Added: WP_128268256.1 blaOXA-757 + Protein Added: WP_128268257.1 blaOXA-758 + Protein Added: WP_128268258.1 blaOXA-759 + Protein Added: WP_128268259.1 blaOXA-760 + Protein Added: WP_128268260.1 blaOXA-761 + Protein Added: WP_128268261.1 blaOXA-762 + Protein Added: WP_128268262.1 blaOXA-763 + Protein Added: WP_128268263.1 blaOXA-764 + Protein Added: WP_128268264.1 blaOXA-765 + Protein Added: WP_128268265.1 blaOXA-766 + Protein Added: WP_128268266.1 blaOXA-767 + Protein Added: WP_128268267.1 blaOXA-768 + Protein Added: WP_128268268.1 blaOXA-769 + Protein Added: WP_128268269.1 blaOXA-770 + Protein Added: WP_128268270.1 blaOXA-771 + Protein Added: WP_128268271.1 blaOXA-772 + Protein Added: WP_128268272.1 blaOXA-773 + Protein Added: WP_128268273.1 blaOXA-774 + Protein Added: WP_128268274.1 blaOXA-775 + Protein Added: WP_128268275.1 blaOXA-776 + Protein Added: WP_128268276.1 blaOXA-781 + Protein Added: WP_128268277.1 blaOXA-782 + Protein Added: WP_128268278.1 blaOXA-783 + Protein Added: WP_128268279.1 blaOXA-786 + Protein Added: WP_128268280.1 blaPDC-317 + Protein Added: WP_128268286.1 blaVEB-20 + Protein Added: WP_128268287.1 blaVIM-62 + Protein Added: WP_128268288.1 qnrS15 +- AMR HMM library Changes: + Prev. Release: 568 + This Release: 571 + Removed: 0 + Added: 3 + HMM Added: NF033714.1 blaBBI + HMM Added: NF033736.1 blaAFM + HMM Added: NF033815.0 blaOXA-364_like + HMM Modified: NF000355.2 ribo_prot_ABC_F updated to NF000355.3 ribo_prot_ABC_F +- Protein family changes: + Prev. Release: 1161 + This Release: 1177 + Removed: 0 + Added: 16 + Family Added: - aac(6')-35 + Family Added: - ant(4')-Ic + Family Added: - ant(6)-Ic + Family Added: NF033736.1 blaAFM + Family Added: NF033714.1 blaBBI + Family Added: NF033815.0 blaOXA-364_like + Family Added: - mecC2 + Family Added: - mecC3 + Family Added: - mphJ + Family Added: - poxtA + Family Added: - rphC + Family Added: - rphD + Family Added: - rph_gen + Family Added: - satA_Ba + Family Added: - taeA + Family Added: - vmlR + Family Changed: NF000355.2 abc-f updated to NF000355.3 abc-f + +--------------------------------------------------------------------- +Changes included in 2018-11-07.1 +--------------------------------------------------------------------- + +Due to a communication error three blaOXA alleles in the AMR database have +been reassigned. Alleles published by Tian, et al. (PMID:30247543) have +replaced them. + +AFY12006.1 JX846494.1 WP_072678505.1 NG_061615.1 were blaOXA-669, now they are blaOXA-732 +AAL47570.1 AY066004.1 WP_114699266.1 NG_061383.1 were blaOXA-666, now they are blaOXA-729 +AXH06203.1 MH684781.1 WP_116786836.1 NG_061623.1 were blaOXA-667, now they are blaOXA-730 + +- Protein changes: + Prev. Release: 4579 + This Release: 4730 + Removed: 0 + Added: 151 + Protein Added: WP_004143591.1 blaSHV-206 + Protein Added: WP_004384957.1 blaCSA-2 + Protein Added: WP_007888761.1 blaCSA-1 + Protein Added: WP_011245929.1 clbB + Protein Added: WP_011707905.1 blaOXA-725 + Protein Added: WP_012116915.1 clbA + Protein Added: WP_015892743.1 clbC + Protein Added: WP_016162389.1 blaOXA-673 + Protein Added: WP_016168805.1 blaOXA-664 + Protein Added: WP_016651348.1 blaOXA-670 + Protein Added: WP_016657654.1 blaOXA-665 + Protein Added: WP_016660101.1 blaOXA-671 + Protein Added: WP_016685888.1 blaOXA-715 + Protein Added: WP_017822040.1 qnrVC10 + Protein Added: WP_023271137.1 blaOXA-672 + Protein Added: WP_023341517.1 blaSHV-211 + Protein Added: WP_031998610.1 blaOXA-716 + Protein Added: WP_032018141.1 blaOXA-717 + Protein Added: WP_032495491.1 blaKLUC-3 + Protein Added: WP_032495492.1 blaKLUC-4 + Protein Added: WP_032974004.1 blaCMA-1 + Protein Added: WP_033179079.1 crpP + Protein Added: WP_034612711.1 blaOXA-668 + Protein Added: WP_056517622.1 blaOXA-669 + Protein Added: WP_057097547.1 aph(2'')-If2 + Protein Added: WP_058652112.1 dfrA34 + Protein Added: WP_064733493.1 blaSHV-207 + Protein Added: WP_064760451.1 qepA4 + Protein Added: WP_064768701.1 qepA7 + Protein Added: WP_077096319.1 blaOXA-724 + Protein Added: WP_081406929.1 blaOXA-674 + Protein Added: WP_081853183.1 blaELM-1 + Protein Added: WP_092689909.1 blaOXA-666 + Protein Added: WP_094166899.1 blaCTX-M-224 + Protein Added: WP_096735335.1 blaOXA-667 + Protein Added: WP_096941464.1 qepA6 + Protein Added: WP_100663667.1 blaKLUC-5 + Protein Added: WP_101150415.1 blaOXA-726 + Protein Added: WP_104159136.1 blaSHV-224 + Protein Added: WP_105620838.1 blaCMA-2 + Protein Added: WP_109232473.1 blaSHV-220 + Protein Added: WP_109638756.1 qepA8 + Protein Added: WP_112021705.1 qepA9 + Protein Added: WP_113334341.1 qepA10 + Protein Added: WP_115196748.1 blaSHV-210 + Protein Added: WP_117241614.1 blaSHV-223 + Protein Added: WP_122630822.1 blaEFM-1 + Protein Added: WP_122630823.1 blaEVM-1 + Protein Added: WP_122630824.1 blaECM-1 + Protein Added: WP_122630825.1 blaEAM-1 + Protein Added: WP_122630826.1 blaGES-38 + Protein Added: WP_122630827.1 blaGES-39 + Protein Added: WP_122630828.1 blaVIM-53 + Protein Added: WP_122630829.1 blaDHT2-1 + Protein Added: WP_122630830.1 blaSPN79-1 + Protein Added: WP_122630831.1 blaCRD3-1 + Protein Added: WP_122630832.1 blaALG6-1 + Protein Added: WP_122630833.1 blaALG11-1 + Protein Added: WP_122630834.1 blaGRD33-1 + Protein Added: WP_122630835.1 blaGRD23-1 + Protein Added: WP_122630836.1 blaCMY-158 + Protein Added: WP_122630837.1 blaCMY-159 + Protein Added: WP_122630838.1 blaSHV-201 + Protein Added: WP_122630839.1 blaSHV-202 + Protein Added: WP_122630840.1 aph(2'') + Protein Added: WP_122630841.1 blaTEM-237 + Protein Added: WP_122630842.1 blaOXA-655 + Protein Added: WP_122630843.1 blaOXA-656 + Protein Added: WP_122630844.1 blaOXA-733 + Protein Added: WP_122630845.1 blaPDC-307 + Protein Added: WP_122630846.1 blaPDC-308 + Protein Added: WP_122630847.1 blaPDC-309 + Protein Added: WP_122630848.1 blaPDC-310 + Protein Added: WP_122630849.1 blaPDC-311 + Protein Added: WP_122630850.1 blaPDC-312 + Protein Added: WP_122630851.1 blaPDC-313 + Protein Added: WP_122630852.1 blaPDC-314 + Protein Added: WP_122630853.1 blaOXA-734 + Protein Added: WP_122630854.1 blaOXA-735 + Protein Added: WP_122630855.1 blaOXA-736 + Protein Added: WP_122630856.1 blaOXA-737 + Protein Added: WP_122630857.1 blaOXA-675 + Protein Added: WP_122630858.1 blaOXA-676 + Protein Added: WP_122630859.1 blaOXA-677 + Protein Added: WP_122630860.1 blaOXA-678 + Protein Added: WP_122630861.1 blaIMP-80 + Protein Added: WP_122630862.1 blaCTX-M-223 + Protein Added: WP_122630863.1 blaSHV-205 + Protein Added: WP_122630864.1 blaOXA-680 + Protein Added: WP_122630865.1 blaSHV-208 + Protein Added: WP_122630866.1 blaSHV-209 + Protein Added: WP_122630867.1 blaSHV-212 + Protein Added: WP_122630868.1 blaSHV-213 + Protein Added: WP_122630869.1 blaSHV-214 + Protein Added: WP_122630870.1 blaSHV-215 + Protein Added: WP_122630871.1 blaSHV-216 + Protein Added: WP_122630872.1 blaSHV-217 + Protein Added: WP_122630873.1 blaSHV-218 + Protein Added: WP_122630874.1 blaSHV-219 + Protein Added: WP_122630875.1 blaSHV-221 + Protein Added: WP_122630876.1 blaSHV-222 + Protein Added: WP_122630877.1 blaSHV-225 + Protein Added: WP_122630878.1 blaSHV-226 + Protein Added: WP_122630879.1 blaSHV-227 + Protein Added: WP_122630880.1 blaSHV-228 + Protein Added: WP_122630881.1 blaOXA-681 + Protein Added: WP_122630882.1 blaPDC-315 + Protein Added: WP_122630883.1 blaPDC-316 + Protein Added: WP_122630884.1 blaOXA-682 + Protein Added: WP_122630885.1 blaOXA-683 + Protein Added: WP_122630886.1 blaOXA-684 + Protein Added: WP_122630887.1 blaOXA-685 + Protein Added: WP_122630888.1 blaOXA-686 + Protein Added: WP_122630889.1 blaOXA-687 + Protein Added: WP_122630890.1 blaOXA-688 + Protein Added: WP_122630891.1 blaOXA-689 + Protein Added: WP_122630892.1 blaOXA-690 + Protein Added: WP_122630893.1 blaOXA-691 + Protein Added: WP_122630894.1 blaOXA-692 + Protein Added: WP_122630895.1 blaOXA-693 + Protein Added: WP_122630896.1 blaOXA-694 + Protein Added: WP_122630897.1 blaOXA-695 + Protein Added: WP_122630898.1 blaOXA-696 + Protein Added: WP_122630899.1 blaOXA-697 + Protein Added: WP_122630900.1 blaOXA-698 + Protein Added: WP_122630901.1 blaOXA-699 + Protein Added: WP_122630902.1 blaOXA-700 + Protein Added: WP_122630903.1 blaOXA-701 + Protein Added: WP_122630904.1 blaOXA-702 + Protein Added: WP_122630905.1 blaOXA-703 + Protein Added: WP_122630906.1 blaOXA-704 + Protein Added: WP_122630907.1 blaOXA-705 + Protein Added: WP_122630908.1 blaOXA-706 + Protein Added: WP_122630909.1 blaOXA-707 + Protein Added: WP_122630910.1 blaOXA-718 + Protein Added: WP_122630911.1 blaOXA-719 + Protein Added: WP_122630912.1 blaOXA-720 + Protein Added: WP_122630913.1 blaOXA-721 + Protein Added: WP_122630914.1 blaOXA-722 + Protein Added: WP_122630915.1 blaOXA-723 + Protein Added: WP_122630916.1 blaOXA-708 + Protein Added: WP_122630917.1 blaOXA-709 + Protein Added: WP_122630918.1 blaOXA-710 + Protein Added: WP_122630919.1 blaOXA-711 + Protein Added: WP_122630920.1 blaOXA-712 + Protein Added: WP_122630921.1 blaOXA-713 + Protein Added: WP_122630922.1 blaOXA-714 + Protein Added: WP_122630923.1 blaOXA-777 + Protein Added: WP_122630924.1 blaOXA-778 + Protein Added: WP_122634438.1 blaOXA-779 + Protein Added: WP_122634439.1 blaOXA-679 + Gene Symbol Modified: WP_010890145.1 qacE_gen updated to WP_010890145.1 qacE + Gene Symbol Modified: WP_053515552.1 qacE_gen updated to WP_053515552.1 qacE + Gene Symbol Modified: WP_063844281.1 cphA updated to WP_063844281.1 cphA3 + Gene Symbol Modified: WP_063854778.1 qepA updated to WP_063854778.1 qepA5 + Gene Symbol Modified: WP_072678505.1 blaOXA-669 updated to WP_072678505.1 blaOXA-732 + Gene Symbol Modified: WP_114699266.1 blaOXA-666 updated to WP_114699266.1 blaOXA-729 + Gene Symbol Modified: WP_116786836.1 blaOXA-667 updated to WP_116786836.1 blaOXA-730 +- AMR HMM library Changes: + Prev. Release: 563 + This Release: 568 + Removed: 0 + Added: 5 + HMM Added: NF033692.1 APH_2pp_I_a_f_h + HMM Added: NF033693.0 AAC_6p_Ie_fam + HMM Added: NF033698.1 blaCSA + HMM Added: NF033700.1 blaCMA + HMM Added: NF033702.0 blaOXA-12_like + HMM Name Modified: NF033666.1 blaOXA-664_like updated to NF033666.1 blaOXA-727_like +- Protein family changes: + Prev. Release: 1133 + This Release: 1161 + Removed: 0 + Added: 28 + Family Added: - aac(6')-Ie2 + Family Added: NF033693.0 aac(6')-Ie_fam + Family Added: NF011706.2 acrB + Family Added: NF007842.1 acrD + Family Added: NF000314.1 adeB/adeJ + Family Added: NF033692.1 aph(2'')-I_a_f_h + Family Added: - aph(2'')-If2 + Family Added: - blaALG11 + Family Added: - blaALG6 + Family Added: NF033700.1 blaCMA + Family Added: - blaCRD3 + Family Added: NF033698.1 blaCSA + Family Added: - blaCrA + Family Added: - blaDHT2 + Family Added: - blaEAM + Family Added: - blaECM + Family Added: - blaEFM + Family Added: - blaELM + Family Added: - blaEVM + Family Added: - blaGRD23 + Family Added: - blaGRD33 + Family Added: NF033702.0 blaOXA-12_like + Family Added: - blaPNGM + Family Added: - blaSPN79 + Family Added: - catV + Family Added: - crpP + Family Added: - dfrA34 + Family Added: - qacE + Family Renamed: NF033666.1 blaOXA-664_like became blaOXA-727_like + +--------------------------------------------------------------------- +Changes included in 2018-09-14.1 +---------------------------------------------------------------------- +- Protein changes: + Prev. Release: 4569 + This Release: 4579 + Removed: 0 + Added: 10 + Protein Added: WP_116786828.1 mcr-4.6 + Protein Added: WP_116786829.1 blaCTX-M-222 + Protein Added: WP_116786830.1 mcr-1.15 + Protein Added: WP_116786831.1 blaTEM-236 + Protein Added: WP_116786832.1 blaKPC-37 + Protein Added: WP_116786834.1 blaPDC-304 + Protein Added: WP_116786836.1 blaOXA-667 + Protein Added: WP_116786837.1 blaPDC-305 + Protein Added: WP_116786838.1 blaPDC-306 + Protein Added: WP_116786839.1 blaIMP-79 +- AMR HMM library Changes: + Prev. Release: 563 + This Release: 563 + Removed: 0 + Added: 0 +- Protein family changes: + Prev. Release: 1133 + This Release: 1133 + Removed: 0 + Added: 0 + +--------------------------------------------------------------------- +Changes included in 2018-08-24.1 +--------------------------------------------------------------------- +- Protein changes: + Prev. Release: 4563 + This Release: 4569 + Removed: 1 + Added: 7 + Protein Removed: WP_063843217.1 catA1 + Protein Added: WP_003436401.1 vanR-Cd + Protein Added: WP_009889012.1 vanZ1 + Protein Added: WP_011861275.1 vanS-Cd + Protein Added: WP_011861276.1 vanG-Cd + Protein Added: WP_020924773.1 blaAXC-1 + Protein Added: WP_072310976.1 mcr-8.2 + Protein Added: WP_072678505.1 blaOXA-669 +- AMR HMM library Changes: + Prev. Release: 563 + This Release: 563 + Removed: 0 + Added: 0 +- Protein family changes: + Prev. Release: 1128 + This Release: 1133 + Removed: 0 + Added: 5 + Family Added: - blaAXC + Family Added: - vanG-Cd + Family Added: - vanR-Cd + Family Added: - vanS-Cd + Family Added: - vanZ1 + +--------------------------------------------------------------------- +Changes included in 2018-08-01.1 +--------------------------------------------------------------------- +- Protein changes: + Prev. Release: 4528 + This Release: 4563 + Removed: 0 + Added: 35 + Protein Added: WP_000622776.1 qacA + Protein Added: WP_001159761.1 blaADC-176 + Protein Added: WP_001211208.1 blaADC-175 + Protein Added: WP_010730188.1 qacZ + Protein Added: WP_013095270.1 blaCMH-4 + Protein Added: WP_032410229.1 blaOXA-663 + Protein Added: WP_033487869.1 blaACT-56 + Protein Added: WP_046887417.1 blaCMH-5 + Protein Added: WP_047052637.1 blaACT-55 + Protein Added: WP_050861789.1 blaACT-64 + Protein Added: WP_070210118.1 blaOXA-658 + Protein Added: WP_094935119.1 blaACT-57 + Protein Added: WP_111772163.1 blaVIM-58 + Protein Added: WP_111976052.1 blaACT-60 + Protein Added: WP_112017656.1 blaACT-61 + Protein Added: WP_112792421.1 blaACT-59 + Protein Added: WP_114699266.1 blaOXA-666 + Protein Added: WP_114699267.1 blaKPC-36 + Protein Added: WP_114699268.1 blaADC-174 + Protein Added: WP_114699269.1 blaADC-177 + Protein Added: WP_114699270.1 blaADC-178 + Protein Added: WP_114699271.1 blaADC-179 + Protein Added: WP_114699272.1 blaADC-180 + Protein Added: WP_114699273.1 blaOXA-661 + Protein Added: WP_114699274.1 blaOXA-662 + Protein Added: WP_114699275.1 mcr-8.1 + Protein Added: WP_114699276.1 blaOXA-659 + Protein Added: WP_114699277.1 blaVIM-60 + Protein Added: WP_114699278.1 mcr-5.3 + Protein Added: WP_114699279.1 blaOXA-660 + Protein Added: WP_114699280.1 blaIMP-76 + Protein Added: WP_114699281.1 blaIMP-77 + Protein Added: WP_114699282.1 blaIMP-78 + Protein Added: WP_114699283.1 blaVIM-59 + Protein Added: WP_114699284.1 blaCTX-M-221 +- AMR HMM library Changes: + Prev. Release: 557 + This Release: 563 + Removed: 0 + Added: 6 + HMM Added: NF033648.1 blaOXA-274_like + HMM Added: NF033666.1 blaOXA-664_like + HMM Added: NF033667.0 blaOXA-55_like + HMM Added: NF033669.1 polymyxin_MCR8 + HMM Added: NF033670.1 polymyxin_MCR6 + HMM Added: NF033671.1 polymyxin_MCR7 +- Protein family changes: + Prev. Release: 1123 + This Release: 1128 + Removed: 0 + Added: 5 + Family Added: - blaOXA-266_fam + Family Added: NF033648.1 blaOXA-274_like + Family Added: NF033667.1 blaOXA-55_like + Family Added: NF033666.1 blaOXA-664_like + Family Added: NF033669.1 mcr-8 + HMM Added: mcr-6 updated to NF033670.1 mcr-6 + HMM Added: mcr-7 updated to NF033671.1 mcr-7 + +Updates in 2018-07-07.1 +- Fix in amr_report.cpp to remove extra field from AMRFinder output + +Updates in 2018-06-27.1 +- Summary: + - Protein sequences + - Removed 1 protein sequence + - Added 290 protein sequences + - Changed the names of 2 proteins + - Gene families + - cfr was reorganized + - HMM library + - 58 HMMs not in the AMR family hierarchy were removed. They were not + used for AMR gene identification so this should have no effect on + AMRFinder output. + - The polymyxin_MCR3 HMM was updated +- Details: + Protein Removed: WP_063945333.1 aac(6')-IIa + Protein Added: WP_000131886.1 aac(3)-VIa + Protein Added: WP_000778180.1 varG + Protein Added: WP_001100752.1 blaPER-10 + Protein Added: WP_002812372.1 blaOXA-578 + Protein Added: WP_002824679.1 blaOXA-595 + Protein Added: WP_002837769.1 blaOXA-579 + Protein Added: WP_002857546.1 blaOXA-592 + Protein Added: WP_002889704.1 blaOXA-591 + Protein Added: WP_002936877.1 blaOXA-623 + Protein Added: WP_011339581.1 blaRHO + Protein Added: WP_011497575.1 blaSHN-1 + Protein Added: WP_011550565.1 blaMYX-1 + Protein Added: WP_011638903.1 mcr-4.3 + Protein Added: WP_012263521.1 mupA + Protein Added: WP_012541790.1 blaLEN-28 + Protein Added: WP_012698469.1 blaLHK-7 + Protein Added: WP_013255389.1 blaSPS-1 + Protein Added: WP_013992183.1 blaZOG-1 + Protein Added: WP_014206564.1 blaOXA-642 + Protein Added: WP_015058260.1 qnrS11 + Protein Added: WP_015266427.1 blaECV-1 + Protein Added: WP_015431537.1 blaROB-2 + Protein Added: WP_015818996.1 blaTTU-1 + Protein Added: WP_016252988.1 blaPDC-286 + Protein Added: WP_021018581.1 catB8 + Protein Added: WP_025006557.1 blaOXA-580 + Protein Added: WP_026025287.1 blaALI-1 + Protein Added: WP_031192893.1 aadA31 + Protein Added: WP_034035338.1 blaPDC-240 + Protein Added: WP_035203840.1 catA10 + Protein Added: WP_038333643.1 blaEBR-2 + Protein Added: WP_038640920.1 qnrB12 + Protein Added: WP_041079981.1 erm(44)v + Protein Added: WP_041258349.1 blaFIA-1 + Protein Added: WP_041385949.1 blaSGM-2 + Protein Added: WP_041449074.1 blaANA-1 + Protein Added: WP_043774378.1 catA13 + Protein Added: WP_043942497.1 blaPST-1 + Protein Added: WP_044600959.1 blaOXA-594 + Protein Added: WP_044779552.1 blaOXA-638 + Protein Added: WP_048236419.1 qnrB85 + Protein Added: WP_052259183.1 erm(42) + Protein Added: WP_052781249.1 blaOXA-583 + Protein Added: WP_052788483.1 blaOXA-611 + Protein Added: WP_052788887.1 blaOXA-581 + Protein Added: WP_052794776.1 blaOXA-625 + Protein Added: WP_052798312.1 blaOXA-609 + Protein Added: WP_052800105.1 blaOXA-597 + Protein Added: WP_052803794.1 blaOXA-601 + Protein Added: WP_052858477.1 blaOXA-637 + Protein Added: WP_053872444.1 blaOXA-639 + Protein Added: WP_053921012.1 blaOXA-603 + Protein Added: WP_057036510.1 blaOXA-629 + Protein Added: WP_058157026.1 blaPDC-271 + Protein Added: WP_058174497.1 blaPDC-250 + Protein Added: WP_058870660.1 blaOXA-651 + Protein Added: WP_058951457.1 blaOXA-652 + Protein Added: WP_061193431.1 blaPDC-298 + Protein Added: WP_064186845.1 qnrS13 + Protein Added: WP_065597326.1 blaALI-2 + Protein Added: WP_065801616.1 mcr-3.20 + Protein Added: WP_065908739.1 qnrB91 + Protein Added: WP_070233680.1 blaOXA-614 + Protein Added: WP_070698497.1 blaPDC-278 + Protein Added: WP_071701819.1 qnrS12 + Protein Added: WP_071846333.1 aac(6')_Serra + Protein Added: WP_073669325.1 blaPDC-285 + Protein Added: WP_075606311.1 blaROB-3 + Protein Added: WP_078207746.1 qnrE2 + Protein Added: WP_078318620.1 blaROB-4 + Protein Added: WP_080699425.1 blaTEM-229 + Protein Added: WP_081048762.1 blaMYO-1 + Protein Added: WP_081666691.1 blaLHK-1 + Protein Added: WP_085843691.1 qnrB95 + Protein Added: WP_087696200.1 blaOXA-576 + Protein Added: WP_087879616.1 mcr-3.19 + Protein Added: WP_088303859.1 blaOXA-624 + Protein Added: WP_094308975.1 mcr-3.22 + Protein Added: WP_094312656.1 mcr-3.21 + Protein Added: WP_094313523.1 mcr-3.23 + Protein Added: WP_094321595.1 mcr-3.24 + Protein Added: WP_094963248.1 aadA31 + Protein Added: WP_096170112.1 qnrS14 + Protein Added: WP_096865225.1 blaPER-12 + Protein Added: WP_100831609.1 blaPDC-245 + Protein Added: WP_103034696.1 blaROB-5 + Protein Added: WP_103252528.1 mcr-3.25 + Protein Added: WP_104009831.1 blaPER-11 + Protein Added: WP_104009832.1 blaPDC-234 + Protein Added: WP_104009833.1 blaPDC-235 + Protein Added: WP_104009834.1 blaPDC-236 + Protein Added: WP_104009835.1 blaPDC-237 + Protein Added: WP_104009836.1 blaPDC-238 + Protein Added: WP_104009837.1 blaPDC-239 + Protein Added: WP_104009838.1 blaPDC-241 + Protein Added: WP_104009839.1 blaPDC-242 + Protein Added: WP_104009840.1 blaPDC-243 + Protein Added: WP_104009841.1 blaPDC-244 + Protein Added: WP_104009842.1 blaPDC-246 + Protein Added: WP_104009843.1 blaPDC-247 + Protein Added: WP_104009844.1 blaPDC-248 + Protein Added: WP_104009846.1 blaVIM-56 + Protein Added: WP_104009847.1 blaCTX-M-178 + Protein Added: WP_104009848.1 blaCTX-M-187 + Protein Added: WP_104009849.1 blaCMY-156 + Protein Added: WP_104009850.1 mcr-1.12 + Protein Added: WP_104009851.1 mcr-7.1 + Protein Added: WP_104009852.1 blaIMP-71 + Protein Added: WP_104009853.1 blaOXA-575 + Protein Added: WP_104009854.1 blaTEM-230 + Protein Added: WP_104009855.1 blaTEM-231 + Protein Added: WP_104009856.1 blaPDC-227 + Protein Added: WP_104009857.1 blaPDC-228 + Protein Added: WP_104009858.1 blaPDC-229 + Protein Added: WP_104009859.1 blaPDC-230 + Protein Added: WP_104009860.1 blaPDC-231 + Protein Added: WP_104009861.1 blaPDC-232 + Protein Added: WP_104009862.1 blaPDC-233 + Protein Added: WP_104531863.1 blaBUT-1 + Protein Added: WP_104531864.1 blaBUT-2 + Protein Added: WP_104531865.1 blaLHK-2 + Protein Added: WP_104531866.1 blaLHK-3 + Protein Added: WP_104531867.1 blaLHK-4 + Protein Added: WP_104531868.1 blaLHK-5 + Protein Added: WP_104531869.1 blaLHK-6 + Protein Added: WP_106672612.1 blaCMY-150 + Protein Added: WP_106924209.1 blaCTX-M-213 + Protein Added: WP_109544237.1 tet(S) + Protein Added: WP_109545031.1 dfrA14 + Protein Added: WP_109545032.1 qnrB11 + Protein Added: WP_109545033.1 vanY-D + Protein Added: WP_109545034.1 qnrB22 + Protein Added: WP_109545035.1 qacF + Protein Added: WP_109545038.1 tet(33) + Protein Added: WP_109545039.1 blaSTA-1 + Protein Added: WP_109545040.1 chrB + Protein Added: WP_109545041.1 aph(3'')-Ib + Protein Added: WP_109545042.1 blaORR-1 + Protein Added: WP_109545044.1 blaKPC-34 + Protein Added: WP_109545045.1 qnrD3 + Protein Added: WP_109545046.1 qnrB81 + Protein Added: WP_109545047.1 qnrB82 + Protein Added: WP_109545048.1 blaOXA-542 + Protein Added: WP_109545049.1 blaNDM-20 + Protein Added: WP_109545050.1 blaCRH-2 + Protein Added: WP_109545051.1 blaCRH-3 + Protein Added: WP_109545053.1 blaIMP-73 + Protein Added: WP_109545054.1 mcr-4.5 + Protein Added: WP_109545055.1 mcr-4.4 + Protein Added: WP_109545056.1 mcr-1.13 + Protein Added: WP_109545057.1 mcr-5.2 + Protein Added: WP_109545058.1 mcr-4.2 + Protein Added: WP_109545059.1 blaTEM-232 + Protein Added: WP_109545060.1 blaCTX-M-208 + Protein Added: WP_109545061.1 blaCTX-M-209 + Protein Added: WP_109545062.1 blaCTX-M-210 + Protein Added: WP_109545063.1 blaCTX-M-211 + Protein Added: WP_109545064.1 blaCTX-M-212 + Protein Added: WP_109545065.1 blaCMY-161 + Protein Added: WP_109545066.1 blaFOX-16 + Protein Added: WP_109545067.1 blaDHA-27 + Protein Added: WP_109545068.1 blaDHA-26 + Protein Added: WP_109545069.1 blaCTX-M-214 + Protein Added: WP_109545070.1 mcr-3.12 + Protein Added: WP_109545071.1 blaOXA-649 + Protein Added: WP_109545072.1 blaOXA-641 + Protein Added: WP_109545073.1 blaFRI-5 + Protein Added: WP_109545074.1 blaGPC-1 + Protein Added: WP_109545075.1 blaOXA-619 + Protein Added: WP_109545076.1 blaOXA-620 + Protein Added: WP_109545077.1 blaOXA-636 + Protein Added: WP_109545078.1 blaOXA-635 + Protein Added: WP_109545079.1 blaOXA-631 + Protein Added: WP_109545080.1 blaOXA-626 + Protein Added: WP_109545081.1 blaOXA-627 + Protein Added: WP_109545082.1 blaOXA-633 + Protein Added: WP_109545083.1 blaOXA-628 + Protein Added: WP_109545084.1 blaOXA-634 + Protein Added: WP_109545085.1 blaOXA-630 + Protein Added: WP_109545086.1 blaOXA-632 + Protein Added: WP_109545087.1 blaOXA-608 + Protein Added: WP_109545088.1 blaOXA-584 + Protein Added: WP_109545089.1 blaOXA-585 + Protein Added: WP_109545090.1 blaOXA-586 + Protein Added: WP_109545091.1 blaOXA-577 + Protein Added: WP_109545092.1 blaOXA-587 + Protein Added: WP_109545093.1 blaOXA-596 + Protein Added: WP_109545094.1 blaOXA-600 + Protein Added: WP_109545095.1 blaOXA-588 + Protein Added: WP_109545096.1 blaOXA-589 + Protein Added: WP_109545097.1 blaOXA-593 + Protein Added: WP_109545098.1 blaOXA-599 + Protein Added: WP_109545099.1 blaOXA-610 + Protein Added: WP_109545100.1 blaOXA-612 + Protein Added: WP_109545101.1 blaOXA-598 + Protein Added: WP_109545102.1 blaOXA-607 + Protein Added: WP_109545103.1 blaOXA-590 + Protein Added: WP_109545104.1 blaOXA-604 + Protein Added: WP_109545105.1 blaOXA-602 + Protein Added: WP_109545106.1 blaOXA-606 + Protein Added: WP_109545107.1 blaOXA-582 + Protein Added: WP_109545108.1 blaOXA-605 + Protein Added: WP_109545109.1 blaOXA-640 + Protein Added: WP_109545110.1 blaOXA-616 + Protein Added: WP_109545111.1 blaOXA-613 + Protein Added: WP_109545112.1 blaOXA-622 + Protein Added: WP_109545113.1 blaOXA-618 + Protein Added: WP_109545114.1 blaOXA-617 + Protein Added: WP_109545115.1 blaOXA-615 + Protein Added: WP_109545116.1 blaOXA-621 + Protein Added: WP_109791184.1 blaTEM-233 + Protein Added: WP_109791185.1 blaPDC-251 + Protein Added: WP_109791186.1 blaPDC-252 + Protein Added: WP_109791187.1 blaPDC-253 + Protein Added: WP_109791188.1 blaPDC-254 + Protein Added: WP_109791189.1 blaPDC-255 + Protein Added: WP_109791190.1 blaPDC-256 + Protein Added: WP_109791191.1 blaPDC-257 + Protein Added: WP_109791192.1 blaPDC-258 + Protein Added: WP_109791193.1 blaPDC-259 + Protein Added: WP_109791194.1 blaPDC-260 + Protein Added: WP_109791195.1 blaPDC-261 + Protein Added: WP_109791196.1 blaPDC-262 + Protein Added: WP_109791197.1 blaPDC-263 + Protein Added: WP_109791198.1 blaPDC-264 + Protein Added: WP_109791199.1 blaPDC-265 + Protein Added: WP_109791200.1 blaPDC-266 + Protein Added: WP_109791201.1 blaPDC-267 + Protein Added: WP_109791202.1 blaPDC-268 + Protein Added: WP_109791203.1 blaPDC-270 + Protein Added: WP_109791204.1 blaPDC-272 + Protein Added: WP_109791205.1 blaPDC-273 + Protein Added: WP_109791206.1 blaPDC-274 + Protein Added: WP_109791207.1 blaIMP-74 + Protein Added: WP_109791208.1 blaIMP-75 + Protein Added: WP_109791209.1 blaCTX-M-216 + Protein Added: WP_109791210.1 blaTEM-234 + Protein Added: WP_109791211.1 blaCTX-M-217 + Protein Added: WP_109791212.1 blaSHV-204 + Protein Added: WP_109791213.1 blaNDM-22 + Protein Added: WP_109791214.1 blaCTX-M-218 + Protein Added: WP_109791215.1 blaCMY-160 + Protein Added: WP_109791216.1 blaOXA-654 + Protein Added: WP_109997726.1 qnrA9 + Protein Added: WP_110092882.1 blaCTX-M-219 + Protein Added: WP_111273842.1 mcr-3.13 + Protein Added: WP_111273843.1 mcr-3.14 + Protein Added: WP_111273844.1 mcr-3.15 + Protein Added: WP_111273845.1 mcr-3.16 + Protein Added: WP_111273846.1 mcr-3.17 + Protein Added: WP_111273847.1 mcr-3.18 + Protein Added: WP_111273848.1 blaGES-35 + Protein Added: WP_111273849.1 blaGES-36 + Protein Added: WP_111273850.1 blaGES-37 + Protein Added: WP_111273851.1 blaCMY-162 + Protein Added: WP_111273852.1 blaKPC-35 + Protein Added: WP_111672883.1 blaPDC-275 + Protein Added: WP_111672884.1 blaPDC-294 + Protein Added: WP_111672885.1 blaPDC-295 + Protein Added: WP_111672886.1 blaPDC-296 + Protein Added: WP_111672887.1 blaPDC-297 + Protein Added: WP_111672888.1 blaPDC-299 + Protein Added: WP_111672889.1 blaPDC-300 + Protein Added: WP_111672890.1 blaPDC-276 + Protein Added: WP_111672891.1 blaPDC-277 + Protein Added: WP_111672892.1 blaPDC-279 + Protein Added: WP_111672893.1 blaPDC-280 + Protein Added: WP_111672894.1 blaPDC-281 + Protein Added: WP_111672895.1 blaPDC-282 + Protein Added: WP_111672896.1 blaPDC-283 + Protein Added: WP_111672897.1 blaPDC-284 + Protein Added: WP_111672898.1 blaPDC-287 + Protein Added: WP_111672899.1 blaPDC-288 + Protein Added: WP_111672900.1 blaPDC-289 + Protein Added: WP_111672901.1 blaPDC-290 + Protein Added: WP_111672902.1 blaCTX-M-220 + Protein Added: WP_111672903.1 blaPDC-291 + Protein Added: WP_111672904.1 blaPDC-292 + Protein Added: WP_111672905.1 blaPDC-293 + Protein Added: WP_111672906.1 blaCMY-163 + Protein Added: WP_111672907.1 blaOXA-657 + Protein Added: WP_111672908.1 blaPDC-301 + Protein Added: WP_111672909.1 blaPDC-302 + Protein Added: WP_111672910.1 blaPDC-303 + Protein Added: WP_111672911.1 blaKPC-23 + Protein Added: WP_111672912.1 blaNDM-23 + Protein Added: WP_111672913.1 blaNDM-24 + Protein Added: WP_111672914.1 blaVIM-57 + Protein Added: WP_111690897.1 cfr(B) + Protein Added: WP_111690898.1 cfr(C) + Protein Modified: WP_011987126.1 cfrC updated to WP_011987126.1 cfr-Cb + Protein Modified: WP_063854808.1 qnrS updated to WP_063854808.1 qnrS10 + HMM Removed: NF000031.1 MFS_efflux_LmrA + HMM Removed: NF000040.1 172051428_tet + HMM Removed: NF000058.1 Erm41 + HMM Removed: NF000060.1 MFS_efflux_LmrB + HMM Removed: NF000106.1 40850658_otr + HMM Removed: NF000131.1 MATE_multi_MepA + HMM Removed: NF000140.3 AAC_6p_Salmo + HMM Removed: NF000217.1 MATE_multi_FepA + HMM Removed: NF000247.1 MexA + HMM Removed: NF000249.1 MexE + HMM Removed: NF000250.1 MexH + HMM Removed: NF000251.1 MexW-MexI + HMM Removed: NF000252.1 MexX + HMM Removed: NF000263.1 MATE_multi_NorM + HMM Removed: NF000282.2 RND_permease_1 + HMM Removed: NF000313.1 adeA-adeI + HMM Removed: NF000314.1 adeB + HMM Removed: NF000315.1 adeC-adeK-oprM + HMM Removed: NF000334.3 drrA + HMM Removed: NF000336.1 emrE + HMM Removed: NF000342.3 glpA_Cterm + HMM Removed: NF000344.1 macA + HMM Removed: NF000345.1 macB + HMM Removed: NF000349.1 mfpA_AE000516.2 + HMM Removed: NF000352.1 norA + HMM Removed: NF000357.1 romA + HMM Removed: NF000391.1 EmrB + HMM Removed: NF010314.2 PRK13751.2 + HMM Removed: NF012135.0 ANT_3pp_9_crypt + HMM Removed: NF012144.2 ramA_TF + HMM Removed: NF012163.2 BaeS_SmeS + HMM Removed: NF012168.1 BlaI_of_BCL + HMM Removed: NF012198.0 MarA_TF + HMM Removed: NF012208.0 SDR_dihy_bifunc + HMM Removed: NF012226.0 AdeS_HK + HMM Removed: NF012227.0 AdeR_RR + HMM Removed: NF012228.1 RobA_TF + HMM Removed: NF028537.1 P_eth_NH2_trans + HMM Removed: NF030466.0 TIGR02052 + HMM Removed: NF030467.0 TIGR02053 + HMM Removed: NF033086.2 penta_rpt_Qnr + HMM Removed: NF033124.1 estX + HMM Removed: NF033134.0 cmlA_floR + HMM Removed: NF033138.1 RND-peri-MexC + HMM Removed: NF033142.1 efflux_OM_AdeC + HMM Removed: NF033143.1 efflux_OM_AdeK + HMM Removed: NF033184.1 B3_Acin_new1 + HMM Removed: NF033480.1 bifunc_MprF + HMM Removed: NF033553.1 MerP_Gpos + HMM Removed: NF033555.1 lyase_MerB + HMM Removed: NF033556.1 MerTP_fusion + HMM Removed: NF033560.1 merT_RC607 + HMM Removed: NF033565.0 trans_MerF + HMM Removed: NF033606.1 heat_AAA_ClpK + HMM Removed: NF033607.0 disagg_AAA_ClpG + HMM Removed: NF033617.1 RND_permease_2 + HMM Removed: NF033627.1 intimin_all + HMM Removed: NF033636.1 acid_shock_Asr + HMM Modified: NF033408.2 polymyxin_MCR3 updated to NF033408.5 polymyxin_MCR3 + Family Removed: - cfrC + Family Added: - cfr(B) + Family Added: - cfr(C) + Family Added: - cfr-Cb + Family Changed: NF033408.2 mcr-3 updated to NF033408.5 mcr-3 + +--------------------------------------------------------------------- +Changes included in 2018-05-15.1 +--------------------------------------------------------------------- +- Data Changes: + Protein Removed: WP_010886396.1 lmr(B) + HMM Added: NF033614.1 APH_6_Ic_gen + HMM Added: NF033617.1 RND_permease_2 + HMM Added: NF033626.1 blaBKC_GPC + HMM Added: NF033627.1 intimin_all + HMM Added: NF033636.1 acid_shock_Asr + HMM Modified: NF000011.1 APH_6_Ic updated to NF000011.2 APH_6_Ic + HMM Modified: NF000221.3 FosA updated to NF000221.4 FosA + HMM Modified: NF000282.1 RND_permease_1 updated to NF000282.2 RND_permease_1 + HMM Modified: NF000428.2 blaFRI updated to NF000428.4 blaFRI + HMM Modified: NF033582.0 blaALI updated to NF033582.2 blaALI + Family Removed: NF000060.1 lmr(B) + Family Added: NF033626.1 blaBKC_GPC + Family Added: - blaGPC +- Algorithm Changes: + - Partial proteins identified as "Method" PARTIAL if length of blast + alignment > 50% and < 90% of database protein. + +--------------------------------------------------------------------- +Changes included in 2018-05-08.1 RELEASE CANDIDATE +--------------------------------------------------------------------- +- Addition of handling for genbank plasmid gff + +--------------------------------------------------------------------- +Changes included in 2018-04-16.1 +--------------------------------------------------------------------- +- Addition of file format checking for FASTA and GFF files before AMRFinder blast and HMM searches are run +- Altered format of fam.tab file to include NF accessions for families +- Removal of non-reportable families from fam.tab