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planemo upload commit 15239f1674081ab51ab8dd75a9a40cf1bfaa93e8
| author | cstrittmatter |
|---|---|
| date | Tue, 28 Jan 2020 10:42:31 -0500 |
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--------------------------------------------------------------------- Changes included in 2020-01-06.1 --------------------------------------------------------------------- This update includes backward incompatible changes to the AMRFinderPlus database format. It is compatible with AMRFinderPlus version 3.6. To use this database version please update to AMRFinderPlus version 3.6. See https://github.com/ncbi/amr/wiki/Upgrading for how to upgrade and https://github.com/evolarjun/amr/wiki/AMRFinderPlus-database for information on the new database format. Some highlights: - Database format has changed to allow AMRFinderPlus to detect promoter mutations and small indels - Many new point mutations, including Escherichia ampC promoter mutations, Klebsiella, and Enterococcus mutations - Small improvements to many product names - Improvements in class and subclass phenotype designations - Modifications and additions of a few HMMs - The usual addition of new alleles submitted to NCBI and others gleaned from the literature - Protein and point mutations: Total in prev: 6443 Total in release: 6622 Removed: 0 Added: 184 Protein Added: ABV01310.1 ltcA heat-labile_enterotoxin_LT_subunit_A Protein Added: ADE89421.1 sslE lipoprotein_metalloprotease_SslE Protein Added: ASK37426.1 aar AggR-activated_transcriptional_regulator_Aar Protein Added: BAB41547.1 mepA multidrug_efflux_MATE_transporter_MepA Protein Added: WP_000378442.1 emrR multidrug_efflux_transporter_EmrAB_transcriptional_repressor_EmrR Protein Added: WP_001132507.1 acrB multidrug_efflux_RND_transporter_permease_subunit_AcrB Protein Added: WP_002289153.1 liaR response_regulator_transcription_factor_LiaR Protein Added: WP_002289154.1 liaS sensor_histidine_kinase_LiaS Protein Added: WP_002289473.1 cls cardiolipin_synthase_Cls Protein Added: WP_002295408.1 liaF three-component_signaling_pathway_regulator_LiaF Protein Added: WP_002355137.1 liaR response_regulator_transcription_factor_LiaR Protein Added: WP_002356022.1 yybT cyclic_dinucleotide_phosphodiesterase_YybT Protein Added: WP_002365182.1 liaS sensor_histidine_kinase_LiaS Protein Added: WP_002371880.1 parC DNA_topoisomerase_IV_subunit_A_ParC Protein Added: WP_002381168.1 liaF three-component_signaling_pathway_regulator_LiaF Protein Added: WP_002389492.1 gshF bifunctional_glutamate--cysteine_ligase/glutathione_synthetase_GshF Protein Added: WP_002413481.1 cls cardiolipin_synthase_Cls Protein Added: WP_002895659.1 pmrA two-component_system_response_regulator_PmrA Protein Added: WP_002911375.1:47:mgrB_W47R mgrB PhoP/PhoQ_regulator_MgrB Protein Added: WP_004147969.1 phoQ two-component_system_sensor_histidine_kinase_PhoQ Protein Added: WP_004150807.1 phoP two-component_system_response_regulator_PhoP Protein Added: WP_004179093.1 pmrB two-component_system_sensor_histidine_kinase_PmrB Protein Added: WP_004184324.1 crrB HAMP_domain-containing_histidine_kinase_CrrB Protein Added: WP_014906821.1 arnC undecaprenyl-phosphate_4-deoxy-4-formamido-L-arabinose_transferase_ArnC Protein Added: WP_033554192.1 parE DNA_topoisomerase_IV_subunit_B_ParE Protein Added: WP_033785346.1 gyrA DNA_gyrase_subunit_A_GyrA Protein Added: WP_048324114.1 blaOKP-B-45 class_A_broad-spectrum_beta-lactamase_OKP-B-45 Protein Added: WP_049003700.1 blaOKP-B-41 class_A_broad-spectrum_beta-lactamase_OKP-B-41 Protein Added: WP_057012521.1 blaPFM-2 subclass_B2_metallo-beta-lactamase_PFM-2 Protein Added: WP_060573544.1 blaACT-77 cephalosporin-hydrolyzing_class_C_beta-lactamase_ACT-77 Protein Added: WP_060655783.1 blaOKP-B-36 class_A_broad-spectrum_beta-lactamase_OKP-B-36 Protein Added: WP_064183695.1 blaOKP-B-16 class_A_broad-spectrum_beta-lactamase_OKP-B-16 Protein Added: WP_080897395.1 blaOKP-D-1 class_A_broad-spectrum_beta-lactamase_OKP-D-1 Protein Added: WP_086259262.1 acrB multidrug_efflux_RND_transporter_permease_subunit_AcrB Protein Added: WP_087771722.1 blaOKP-B-34 class_A_broad-spectrum_beta-lactamase_OKP-B-34 Protein Added: WP_087833272.1 blaOKP-B-21 class_A_broad-spectrum_beta-lactamase_OKP-B-21 Protein Added: WP_100886243.1 blaOXA-895 OXA-229_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-895 Protein Added: WP_101982161.1 parC DNA_topoisomerase_IV_subunit_A_ParC Protein Added: WP_114508147.1 blaOKP-B-40 class_A_broad-spectrum_beta-lactamase_OKP-B-40 Protein Added: WP_115256011.1 parC DNA_topoisomerase_IV_subunit_A_ParC Protein Added: WP_117036963.1 gyrA DNA_gyrase_subunit_A_GyrA Protein Added: WP_122543028.1 blaOKP-B-22 class_A_broad-spectrum_beta-lactamase_OKP-B-22 Protein Added: WP_125353308.1 qnrB96 quinolone_resistance_pentapeptide_repeat_protein_QnrB96 Protein Added: WP_130202201.1 blaVIM-69 subclass_B1_metallo-beta-lactamase_VIM-69 Protein Added: WP_131419583.1 blaTEM-238 class_A_beta-lactamase_TEM-238 Protein Added: WP_136034107.1 blaOKP-C-1 class_A_broad-spectrum_beta-lactamase_OKP-C-1 Protein Added: WP_137277832.1 gyrA DNA_gyrase_subunit_A_GyrA Protein Added: WP_156404644.1 blaADC-221 class_C_beta-lactamase_ADC-221 Protein Added: WP_156404645.1 blaCMH-6 class_C_beta-lactamase_CMH-6 Protein Added: WP_156404646.1 blaCMY-168 class_C_beta-lactamase_CMY-168 Protein Added: WP_156404647.1 blaCMY-169 class_C_beta-lactamase_CMY-169 Protein Added: WP_156404648.1 blaCMY-170 class_C_beta-lactamase_CMY-170 Protein Added: WP_156404649.1 blaCTX-M-143 class_A_extended-spectrum_beta-lactamase_CTX-M-143 Protein Added: WP_156404650.1 blaCTX-M-230 class_A_extended-spectrum_beta-lactamase_CTX-M-230 Protein Added: WP_156404651.1 blaCTX-M-231 class_A_extended-spectrum_beta-lactamase_CTX-M-231 Protein Added: WP_156404652.1 blaCTX-M-232 class_A_extended-spectrum_beta-lactamase_CTX-M-232 Protein Added: WP_156404653.1 blaCTX-M-233 class_A_extended-spectrum_beta-lactamase_CTX-M-233 Protein Added: WP_156404654.1 blaMOX-14 CMY-1/MOX_family_class_C_beta-lactamase_MOX-14 Protein Added: WP_156404655.1 blaNDM-26 subclass_B1_metallo-beta-lactamase_NDM-26 Protein Added: WP_156404656.1 blaNDM-29 subclass_B1_metallo-beta-lactamase_NDM-29 Protein Added: WP_156404657.1 blaOKP-B-24 class_A_broad-spectrum_beta-lactamase_OKP-B-24 Protein Added: WP_156404658.1 blaOXA-896 class_D_beta-lactamase_OXA-896 Protein Added: WP_156404659.1 blaPER-14 class_A_extended-spectrum_beta-lactamase_PER-14 Protein Added: WP_156404660.1 blaPFM-3 subclass_B2_metallo-beta-lactamase_PFM-3 Protein Added: WP_156404661.1 blaSHV-115 class_A_extended-spectrum_beta-lactamase_SHV-115 Protein Added: WP_156404662.1 blaVEB-23 class_A_extended-spectrum_beta-lactamase_VEB-23 Protein Added: WP_156404663.1 blaVEB-24 class_A_extended-spectrum_beta-lactamase_VEB-24 Changes to existing protein and point mutation records: Changed mepA accesssion: Q7A7N0.1 -> BAB41547.1 Changed ltcA accession: ABV01314.1 -> ABV01310.1 Changed aar accession: AVL28824.1 -> ASK37426.1 Changed reference sequence for Escherichia parE point mutations: WP_000195296.1 -> WP_033554192.1 Changed reference sequence for Escherichia acrB point mutations: WP_097509477.1 -> WP_086259262.1 16S_A1055G NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_A1408G NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + subclass AMINOGLYCOSIDE -> GENTAMICIN C/NEOMYCIN/PAROMOMYCIN 16S_A1499G NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_A1519C NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_A1519G NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_A1519T NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_A523C NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_A794G NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_A794T NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_A964G NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_C1054T NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_C1065T NC_003197.2 genbank_nucleotide_accession -> AE006468.2 genbank_strand_orientation -> + 16S_C1066T NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_C1192T NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_C1192T NC_003197.2 genbank_nucleotide_accession -> AE006468.2 genbank_strand_orientation -> + 16S_C528T NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_G1053A NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_G1058C NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_G1064A NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + subclass KANAMYCIN -> SPECTINOMYCIN 16S_G1064C NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_G1064T NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_G1068A NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_G527T NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_G926A NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_G926C NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_G926T NC_000913.3 genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + 16S_T1406A NC_000913.3 class AMINOGLYCOSIDE -> AMINGLYCOSIDE genbank_nucleotide_accession -> U00096.3 genbank_strand_orientation -> + subclass G418 -> G418/TOBRAMYCIN 23S_A2058G NC_004431.1 genbank_nucleotide_accession -> AE014075.1 genbank_strand_orientation -> + subclass MACROLIDE -> AZITHROMYCIN/ERYTHROMYCIN/TELITHROMYCIN 23S_A2058T NC_004431.1 genbank_nucleotide_accession -> AE014075.1 genbank_strand_orientation -> + subclass MACROLIDE -> AZITHROMYCIN/ERYTHROMYCIN/TELITHROMYCIN 23S_A2074C NC_002163.1 genbank_nucleotide_accession -> AL111168.1 genbank_strand_orientation -> + 23S_A2074G NC_002163.1 genbank_nucleotide_accession -> AL111168.1 genbank_strand_orientation -> + 23S_A2074T NC_002163.1 genbank_nucleotide_accession -> AL111168.1 genbank_strand_orientation -> + 23S_A2075G NC_002163.1 genbank_nucleotide_accession -> AL111168.1 genbank_strand_orientation -> + 23S_C2611T NC_004431.1 genbank_nucleotide_accession -> AE014075.1 genbank_strand_orientation -> + subclass MACROLIDE -> ERYTHROMYCIN/TELITHROMYCIN 23S_C2627A NC_002163.1 genbank_nucleotide_accession -> AL111168.1 genbank_strand_orientation -> + 23S_G2032A NC_004431.1 class MACROLIDE/OXAZOLIDINONE -> LINCOSAMIDE/OXAZOLIDINONE genbank_nucleotide_accession -> AE014075.1 genbank_strand_orientation -> + subclass MACROLIDE/OXAZOLIDINONE -> CLINDAMYCIN/LINEZOLID 23S_G2032C NC_004431.1 genbank_nucleotide_accession -> AE014075.1 genbank_strand_orientation -> + subclass OXAZOLIDINONE -> LINEZOLID 23S_G2032T NC_004431.1 genbank_nucleotide_accession -> AE014075.1 genbank_strand_orientation -> + subclass MACROLIDE/OXAZOLIDINONE -> CLARITHROMYCIN/LINEZOLID 23S_G2057A NC_004431.1 class MACROLIDE/PHENICOL -> MULTIDRUG genbank_nucleotide_accession -> AE014075.1 genbank_strand_orientation -> + subclass MACROLIDE/CHLORAMPHENICOL -> CHLORAMPHENICOL/ERYTHROMYCIN/TELITHROMYCIN 23S_G2447T NC_004431.1 genbank_nucleotide_accession -> AE014075.1 genbank_strand_orientation -> + subclass OXAZOLIDINONE -> LINEZOLID 23S_T754A NC_004431.1 genbank_nucleotide_accession -> AE014075.1 genbank_strand_orientation -> + subclass MACROLIDE -> ERYTHROMYCIN/TELITHROMYCIN 50S_L22_A103C WP_002851214.1 genbank_protein_accession -> CAL35796.1 50S_L22_A103V WP_002779996.1 genbank_protein_accession -> AJW59082.1 50S_L22_A103V WP_002851214.1 genbank_protein_accession -> CAL35796.1 50S_L22_A84D WP_002779996.1 genbank_protein_accession -> AJW59082.1 50S_L22_A84D WP_002851214.1 genbank_protein_accession -> CAL35796.1 50S_L22_A88E WP_002779996.1 genbank_protein_accession -> AJW59082.1 50S_L22_A88E WP_002851214.1 genbank_protein_accession -> CAL35796.1 50S_L22_G86E WP_002779996.1 genbank_protein_accession -> AJW59082.1 50S_L22_G86E WP_002851214.1 genbank_protein_accession -> CAL35796.1 50S_L22_G86V WP_002779996.1 genbank_protein_accession -> AJW59082.1 50S_L22_G86V WP_002851214.1 genbank_protein_accession -> CAL35796.1 astA AAA20885.1 class VIRULENCE -> subclass astA -> arsB AAA21095.1 blacklisted_taxa Escherichia -> arsC AAA21096.1 blacklisted_taxa Escherichia -> arsB AAA25637.1 blacklisted_taxa Staphylococcus -> arsB AAA27588.1 blacklisted_taxa Staphylococcus -> arsC AAB09628.1 blacklisted_taxa Escherichia -> ehxA AAC24352.1 product_name enterohemolysin -> enterohemolysin EhxA astA AAD43578.1 class VIRULENCE -> subclass astA -> astA AAD43579.1 class VIRULENCE -> subclass astA -> astA AAM88299.1 class VIRULENCE -> subclass astA -> ehxA AAZ76497.1 product_name enterohemolysin -> enterohemolysin EhxA ehxA ABQ02442.1 product_name enterohemolysin -> enterohemolysin EhxA ehxA ABQ02443.1 product_name enterohemolysin -> enterohemolysin EhxA ehxA ABQ02445.1 product_name enterohemolysin -> enterohemolysin EhxA ehxA ABQ02447.1 product_name enterohemolysin -> enterohemolysin EhxA ehxA ABQ02448.1 product_name enterohemolysin -> enterohemolysin EhxA emrD3 ABQ18953.1 blacklisted_taxa Vibrio_cholerae -> kdeA ABR76310.1 blacklisted_taxa Klebsiella -> class -> EFFLUX subclass -> EFFLUX ehxA ACL51961.1 product_name enterohemolysin -> enterohemolysin EhxA emrD ACN65732.1 class -> EFFLUX subclass -> EFFLUX amvA ACQ82816.1 class -> EFFLUX subclass -> EFFLUX astA ADI59685.1 class VIRULENCE -> subclass astA -> ehxA ADZ45128.1 product_name enterohemolysin -> enterohemolysin EhxA asr BAA15331.2 blacklisted_taxa Escherichia -> arsB BAA24823.1 blacklisted_taxa Escherichia -> arsC BAA24824.1 blacklisted_taxa Escherichia, Klebsiella -> ehxA BAA31774.1 product_name enterohemolysin -> enterohemolysin EhxA fieF BAB89353.1 blacklisted_taxa Klebsiella -> fieF BAE77395.1 blacklisted_taxa Escherichia, Salmonella -> emrD BAE77620.1 blacklisted_taxa Escherichia -> class -> EFFLUX subclass -> EFFLUX arsR BAE77793.1 blacklisted_taxa Escherichia -> ehxA CAA63849.1 product_name enterohemolysin -> enterohemolysin EhxA emrD EFF04178.1 class -> EFFLUX subclass -> EFFLUX silF KGL71342.1 product_name Ag(+)/Cu(+) efflux RND transporter periplasmic metallochaperone SilF -> Cu(+)/Ag(+) efflux RND transporter periplasmic metallochaperone SilF dfrA18 WP_001031075.1 product_name trimethoprim-resistant dihydrofolate reductase Dfr18 -> trimethoprim-resistant dihydrofolate reductase DfrA18 mphK WP_003246254.1 product_name macrolide 2'-phosphotransferase MphJ -> macrolide 2'-phosphotransferase MphK blaOKP-B-6 WP_004205995.1 gene_family blaOKP -> blaOKP-B ampC WP_006178946.1 product_name CMY2/MIR/ACT/EC family class c beta-lactamase -> CMY2/MIR/ACT/EC family class C beta-lactamase blaOKP-B-8 WP_017900346.1 gene_family blaOKP -> blaOKP-B blaOKP-A-17 WP_023289605.1 gene_family blaOKP -> blaOKP-A blaOKP-B-23 WP_023318187.1 gene_family blaOKP -> blaOKP-B blaOKP-A-2 WP_032452758.1 gene_family blaOKP -> blaOKP-A blaOKP-B-1 WP_032456002.1 gene_family blaOKP -> blaOKP-B blaPAC-1 WP_034051940.1 product_name class C beta-lactamase PAC-1 -> inhibitior-resistant cephalosporin-hydrolyzing class C beta-lactamase PAC-1 subclass BETA-LACTAM -> CEPHALOSPORIN blaOKP-A-3 WP_044522859.1 gene_family blaOKP -> blaOKP-A blaOKP-A-8 WP_048334865.1 gene_family blaOKP -> blaOKP-A blaOKP-B-7 WP_057215100.1 gene_family blaOKP -> blaOKP-B ampC WP_057991970.1 product_name class C beta-lactamase -> MCA family class C beta-lactamase blaOKP-A-6 WP_060590773.1 gene_family blaOKP -> blaOKP-A ampC WP_063406924.1 product_name CMY2/MIR/ACT/EC family class c beta-lactamase -> CMY2/MIR/ACT/EC family class C beta-lactamase blaOKP-B WP_063842745.1 gene_family blaOKP -> blaOKP-B blaOKP-A-1 WP_063860896.1 gene_family blaOKP -> blaOKP-A blaOKP-A-10 WP_063860897.1 gene_family blaOKP -> blaOKP-A blaOKP-A-11 WP_063860898.1 gene_family blaOKP -> blaOKP-A blaOKP-A-12 WP_063860899.1 gene_family blaOKP -> blaOKP-A blaOKP-A-13 WP_063860900.1 gene_family blaOKP -> blaOKP-A blaOKP-A-14 WP_063860901.1 gene_family blaOKP -> blaOKP-A blaOKP-A-15 WP_063860902.1 gene_family blaOKP -> blaOKP-A blaOKP-A-16 WP_063860903.1 gene_family blaOKP -> blaOKP-A blaOKP-A-4 WP_063860904.1 gene_family blaOKP -> blaOKP-A blaOKP-A-5 WP_063860905.1 gene_family blaOKP -> blaOKP-A blaOKP-A-7 WP_063860906.1 gene_family blaOKP -> blaOKP-A blaOKP-A-9 WP_063860907.1 gene_family blaOKP -> blaOKP-A blaOKP-B-10 WP_063860908.1 gene_family blaOKP -> blaOKP-B blaOKP-B-11 WP_063860909.1 gene_family blaOKP -> blaOKP-B blaOKP-B-13 WP_063860910.1 gene_family blaOKP -> blaOKP-B blaOKP-B-17 WP_063860911.1 gene_family blaOKP -> blaOKP-B blaOKP-B-18 WP_063860912.1 gene_family blaOKP -> blaOKP-B blaOKP-B-19 WP_063860913.1 gene_family blaOKP -> blaOKP-B blaOKP-B-2 WP_063860914.1 gene_family blaOKP -> blaOKP-B blaOKP-B-20 WP_063860915.1 gene_family blaOKP -> blaOKP-B blaOKP-B-3 WP_063860916.1 gene_family blaOKP -> blaOKP-B blaOKP-B-4 WP_063860917.1 gene_family blaOKP -> blaOKP-B blaOKP-B-5 WP_063860923.1 gene_family blaOKP -> blaOKP-B blaOKP-B-9 WP_063860931.1 gene_family blaOKP -> blaOKP-B icr-Mo WP_082741435.1 class -> COLISTIN subclass -> COLISTIN blaPDC-245 WP_100831609.1 product_name class C beta-lactamase PDC-245 -> inhibitor-resistant class C beta-lactamase PDC-245 blaPDC-270 WP_109791203.1 product_name class C beta-lactamase PDC-270 -> inhibitor-resistant class C beta-lactamase PDC-270 blaPDC-322 WP_138403314.1 product_name class C beta-lactamase PDC-322 -> inhibitor-resistant class C beta-lactamase PDC-322 blaKPC-41 WP_148044419.1 product_name carbapenem-hydrolyzing class A beta-lactamase KPC-41 -> inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-41 blaPDC-346 WP_148044438.1 product_name class C beta-lactamase PDC-346 -> inhibitor-resistant class C beta-lactamase PDC-346 blaPDC-381 WP_148044467.1 product_name class C beta-lactamase PDC-381 -> inhibitor-resistant class C beta-lactamase PDC-381 acrR_R45C WP_000101737.1 genbank_protein_accession -> AAC73566.1 product_name transcriptional regulator -> transcriptional regulator AcrR basR_G15R WP_094970923.1 genbank_protein_accession -> OZX69954.1 basR_G53A WP_094970923.1 genbank_protein_accession -> OZX69954.1 basR_G53C WP_094970923.1 genbank_protein_accession -> OZX69954.1 basR_G53E WP_094970923.1 genbank_protein_accession -> OZX69954.1 basR_G53R WP_094970923.1 genbank_protein_accession -> OZX69954.1 basR_G53S WP_094970923.1 genbank_protein_accession -> OZX69954.1 basR_G53V WP_094970923.1 genbank_protein_accession -> OZX69954.1 basR_G53W WP_094970923.1 genbank_protein_accession -> OZX69954.1 basR_L105P WP_094970923.1 genbank_protein_accession -> OZX69954.1 basR_R81L WP_094970923.1 genbank_protein_accession -> OZX69954.1 basR_R81S WP_094970923.1 genbank_protein_accession -> OZX69954.1 basR_S39I WP_094970923.1 genbank_protein_accession -> OZX69954.1 cmeR_G86A WP_002843095.1 genbank_protein_accession -> EAH9016342.1 cyaA_S352T WP_000281668.1 genbank_protein_accession -> CDJ73082.1 product_name adenylate cyclase -> adenylate cyclase CyaA fabG_Y151V WP_001718014.1 genbank_protein_accession -> EMW23334.1 product_name beta-ketoacyl-ACP reductase -> beta-ketoacyl-ACP reductase FabG fabI_F203A WP_000506490.1 genbank_protein_accession -> AAC74370.1 fabI_F203C WP_000506490.1 genbank_protein_accession -> AAC74370.1 fabI_F203L WP_000506490.1 genbank_protein_accession -> AAC74370.1 fabI_G93A WP_000506490.1 genbank_protein_accession -> AAC74370.1 fabI_G93S WP_000506490.1 genbank_protein_accession -> AAC74370.1 fabI_G93V WP_000506490.1 genbank_protein_accession -> AAC74370.1 folP_P64A WP_000764731.1 genbank_protein_accession -> GDV24718.1 product_name dihydropteroate synthase -> dihydropteroate synthase FolP folP_P64H WP_000764731.1 genbank_protein_accession -> GDV24718.1 product_name dihydropteroate synthase -> dihydropteroate synthase FolP folP_P64L WP_000764731.1 genbank_protein_accession -> GDV24718.1 product_name dihydropteroate synthase -> dihydropteroate synthase FolP folP_P64R WP_000764731.1 genbank_protein_accession -> GDV24718.1 product_name dihydropteroate synthase -> dihydropteroate synthase FolP folP_P64S WP_000764731.1 genbank_protein_accession -> GDV24718.1 product_name dihydropteroate synthase -> dihydropteroate synthase FolP gyrA_A119E WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_A119S WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_A119V WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_A131G WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_A196E WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_A51V WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_A67P WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_A67S WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_A70T WP_002857904.1 genbank_protein_accession -> CAL35145.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_A84P WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_A84V WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D72G WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D82G WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D82G WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D82N WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D85Y WP_002857904.1 genbank_protein_accession -> CAL35145.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D87G WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D87G WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D87H WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D87K WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D87N WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D87N WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D87V WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D87Y WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D87Y WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D90A WP_002857904.1 genbank_protein_accession -> CAL35145.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D90N WP_002779062.1 genbank_protein_accession -> AJW58405.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D90N WP_002857904.1 genbank_protein_accession -> CAL35145.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D90T WP_002857904.1 genbank_protein_accession -> CAL35145.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D90Y WP_002779062.1 genbank_protein_accession -> AJW58405.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_D90Y WP_002857904.1 genbank_protein_accession -> CAL35145.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_E139A WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_G81C WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_G81C WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_G81D WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_G81H WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_G81S WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_H80P WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_L98V WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_N57K WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_P104S WP_002779062.1 genbank_protein_accession -> AJW58405.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_P104S WP_002857904.1 genbank_protein_accession -> CAL35145.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_Q106H WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_Q106R WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_S83A WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_S83A WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_S83F WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_S83F WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_S83I WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_S83L WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_S83V WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_S83W WP_001281243.1 genbank_protein_accession -> AXO84158.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_S83Y WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_S97P WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_T86A WP_002779062.1 genbank_protein_accession -> AJW58405.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_T86A WP_002857904.1 genbank_protein_accession -> CAL35145.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_T86I WP_002779062.1 genbank_protein_accession -> AJW58405.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_T86I WP_002857904.1 genbank_protein_accession -> CAL35145.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_T86K WP_002779062.1 genbank_protein_accession -> AJW58405.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_T86K WP_002857904.1 genbank_protein_accession -> CAL35145.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_T86V WP_002779062.1 genbank_protein_accession -> AJW58405.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_T86V WP_002857904.1 genbank_protein_accession -> CAL35145.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrA_V73I WP_001281271.1 genbank_protein_accession -> EAB4993534.1 product_name DNA gyrase subunit A -> DNA gyrase subunit A GyrA gyrB_D426N WP_000072067.1 genbank_protein_accession -> BAE77595.1 product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB gyrB_E466D WP_000072047.1 genbank_protein_accession -> AHP21689.1 product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB gyrB_K447E WP_000072067.1 genbank_protein_accession -> BAE77595.1 product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB subclass QUINOLONE -> NALIDIXIC ACID gyrB_R136C WP_000072067.1 genbank_protein_accession -> BAE77595.1 product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB gyrB_R136E WP_000072067.1 genbank_protein_accession -> BAE77595.1 product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB gyrB_R136G WP_000072067.1 genbank_protein_accession -> BAE77595.1 product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB gyrB_R136H WP_000072067.1 genbank_protein_accession -> BAE77595.1 product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB gyrB_R136I WP_000072067.1 genbank_protein_accession -> BAE77595.1 product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB gyrB_R136L WP_000072067.1 genbank_protein_accession -> BAE77595.1 product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB gyrB_R136S WP_000072067.1 genbank_protein_accession -> BAE77595.1 product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB gyrB_R438L WP_000072047.1 genbank_protein_accession -> AHP21689.1 product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB gyrB_S464F WP_000072047.1 genbank_protein_accession -> AHP21689.1 product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB subclass QUINOLONE -> CIPROFLOXACIN gyrB_S464Y WP_000072047.1 genbank_protein_accession -> AHP21689.1 product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB subclass QUINOLONE -> CIPROFLOXACIN gyrB_Y421C WP_000072047.1 genbank_protein_accession -> AHP21689.1 product_name DNA topoisomerase (ATP-hydrolyzing) subunit B -> DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB lon_P403L WP_001295325.1 genbank_protein_accession -> EQY31068.1 marR_A70T WP_000843414.1 genbank_protein_accession -> AAC74603.2 product_name MarR family transcriptional regulator -> transcriptional regulator MarR marR_E31STOP WP_000843414.1 genbank_protein_accession -> AAC74603.2 product_name MarR family transcriptional regulator -> transcriptional regulator MarR marR_I49S WP_000843414.1 genbank_protein_accession -> AAC74603.2 product_name MarR family transcriptional regulator -> transcriptional regulator MarR marR_L78M WP_000843414.1 genbank_protein_accession -> AAC74603.2 product_name MarR family transcriptional regulator -> transcriptional regulator MarR marR_R73C WP_000843414.1 genbank_protein_accession -> AAC74603.2 product_name MarR family transcriptional regulator -> transcriptional regulator MarR marR_R73S WP_000843414.1 genbank_protein_accession -> AAC74603.2 product_name MarR family transcriptional regulator -> transcriptional regulator MarR marR_R77C WP_000843414.1 genbank_protein_accession -> AAC74603.2 product_name MarR family transcriptional regulator -> transcriptional regulator MarR marR_R77L WP_000843414.1 genbank_protein_accession -> AAC74603.2 product_name MarR family transcriptional regulator -> transcriptional regulator MarR marR_R94H WP_000843414.1 genbank_protein_accession -> AAC74603.2 product_name MarR family transcriptional regulator -> transcriptional regulator MarR marR_R94S WP_000843414.1 genbank_protein_accession -> AAC74603.2 product_name MarR family transcriptional regulator -> transcriptional regulator MarR marR_S3N WP_000843414.1 genbank_protein_accession -> AAC74603.2 product_name MarR family transcriptional regulator -> transcriptional regulator MarR marR_V45E WP_000843414.1 genbank_protein_accession -> AAC74603.2 product_name MarR family transcriptional regulator -> transcriptional regulator MarR marR_V96E WP_000843414.1 genbank_protein_accession -> AAC74603.2 product_name MarR family transcriptional regulator -> transcriptional regulator MarR murA_C115D WP_000357259.1 genbank_protein_accession -> AIL15701.1 product_name UDP-N-acetylglucosamine 1-carboxyvinyltransferase -> UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA murA_C115E WP_000357259.1 genbank_protein_accession -> AIL15701.1 product_name UDP-N-acetylglucosamine 1-carboxyvinyltransferase -> UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA murA_C115S WP_000357259.1 genbank_protein_accession -> AIL15701.1 product_name UDP-N-acetylglucosamine 1-carboxyvinyltransferase -> UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA murA_D396N WP_000357259.1 genbank_protein_accession -> AIL15701.1 product_name UDP-N-acetylglucosamine 1-carboxyvinyltransferase -> UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA murA_L370I WP_000357259.1 genbank_protein_accession -> AIL15701.1 product_name UDP-N-acetylglucosamine 1-carboxyvinyltransferase -> UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA nfsA_G131D WP_089631889.1 genbank_protein_accession -> OYN67948.1 subclass NITROFURAN -> NITROFURANTOIN nfsA_K141STOP WP_089631889.1 genbank_protein_accession -> OYN67948.1 subclass NITROFURAN -> NITROFURANTOIN nfsA_Q44STOP WP_089631889.1 genbank_protein_accession -> OYN67948.1 subclass NITROFURAN -> NITROFURANTOIN nfsA_R133S WP_089631889.1 genbank_protein_accession -> OYN67948.1 subclass NITROFURAN -> NITROFURANTOIN nfsA_R15C WP_089631889.1 genbank_protein_accession -> OYN67948.1 subclass NITROFURAN -> NITROFURANTOIN nfsA_R203C WP_089631889.1 genbank_protein_accession -> OYN67948.1 subclass NITROFURAN -> NITROFURANTOIN nfsA_R203L WP_089631889.1 genbank_protein_accession -> OYN67948.1 subclass NITROFURAN -> NITROFURANTOIN nfsA_S33R WP_089631889.1 genbank_protein_accession -> OYN67948.1 subclass NITROFURAN -> NITROFURANTOIN ompF_G141D WP_000977920.1 genbank_protein_accession -> AAC74015.1 product_name outer membrane protein F -> outer membrane protein F OmpF ompF_G141E WP_000977920.1 genbank_protein_accession -> AAC74015.1 product_name outer membrane protein F -> outer membrane protein F OmpF parC_A108T WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_A108V WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_A56T WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_A85T WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_D111H WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_E84A WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_E84G WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_E84G WP_001281910.1 genbank_protein_accession -> EAW2725281.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_E84K WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_E84K WP_001281910.1 genbank_protein_accession -> EAW2725281.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_E84V WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_F60I WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_F60L WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_G78D WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_G78D WP_001281910.1 genbank_protein_accession -> EAW2725281.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_G78K WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_S129P WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_S57T WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_S80F WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_S80I WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_S80I WP_001281910.1 genbank_protein_accession -> EAW2725281.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_S80L WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_S80R WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_S80R WP_001281910.1 genbank_protein_accession -> EAW2725281.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_S80Y WP_001281881.1 genbank_protein_accession -> AAC76055.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_T66I WP_001281910.1 genbank_protein_accession -> EAW2725281.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parC_W106G WP_001281910.1 genbank_protein_accession -> EAW2725281.1 product_name DNA topoisomerase IV subunit A -> DNA topoisomerase IV subunit A ParC parE_A499T WP_000195318.1 genbank_protein_accession -> ATQ05934.1 product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE parE_E454G WP_000195318.1 genbank_protein_accession -> ATQ05934.1 product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE parE_H462Y WP_000195318.1 genbank_protein_accession -> ATQ05934.1 product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE parE_M438I WP_000195318.1 genbank_protein_accession -> ATQ05934.1 product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE parE_S458P WP_000195318.1 genbank_protein_accession -> ATQ05934.1 product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE parE_V461G WP_000195318.1 genbank_protein_accession -> ATQ05934.1 product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE parE_V514G WP_000195318.1 genbank_protein_accession -> ATQ05934.1 product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE parE_V521F WP_000195318.1 genbank_protein_accession -> ATQ05934.1 product_name DNA topoisomerase IV subunit B -> DNA topoisomerase IV subunit B ParE pmrA_G15R WP_000697899.1 genbank_protein_accession -> EAB2345955.1 pmrA_G53E WP_000697899.1 genbank_protein_accession -> EAB2345955.1 pmrA_G53R WP_000697899.1 genbank_protein_accession -> EAB2345955.1 pmrA_R81C WP_000697899.1 genbank_protein_accession -> EAB2345955.1 pmrA_R81H WP_000697899.1 genbank_protein_accession -> EAB2345955.1 pmrB_A159P WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_A159V WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_C84R WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_C84Y WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_E121A WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_E121K WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_E121Q WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_E166K WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_E166K WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_G206D WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_G206R WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_G206W WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_L10P WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_L10R WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_L14F WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_L14R WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_L14S WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_L22P WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_M186I WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_N130Y WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_P94L WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_P94Q WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_P94Q WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_P94S WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_R155P WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_S124P WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_S29R WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_S305R WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_T147A WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_T147P WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_T156M WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_T156M WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_T156P WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_T92A WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_V161G WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_V161G WP_001300761.1 genbank_protein_accession -> KHH69629.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_V161L WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB pmrB_V161M WP_001212189.1 genbank_protein_accession -> EAM5131532.1 product_name two-component sensor histidine kinase -> two-component system sensor histidine kinase PmrB ptsI_V25I WP_000623140.1 genbank_protein_accession -> CDJ72759.1 product_name phosphoenolpyruvate--protein phosphotransferase -> phosphoenolpyruvate--protein phosphotransferase PtsI ramR_E160D WP_000113609.1 genbank_protein_accession -> ACH50230.1 product_name TetR/AcrR family transcriptional regulator -> TetR/AcrR family transcriptional regulator RamR ramR_G25A WP_000113609.1 genbank_protein_accession -> ACH50230.1 product_name TetR/AcrR family transcriptional regulator -> TetR/AcrR family transcriptional regulator RamR ramR_M84I WP_000113609.1 genbank_protein_accession -> ACH50230.1 product_name TetR/AcrR family transcriptional regulator -> TetR/AcrR family transcriptional regulator RamR ramR_R46P WP_000113609.1 genbank_protein_accession -> ACH50230.1 product_name TetR/AcrR family transcriptional regulator -> TetR/AcrR family transcriptional regulator RamR ramR_T18P WP_000113609.1 genbank_protein_accession -> ACH50230.1 product_name TetR/AcrR family transcriptional regulator -> TetR/AcrR family transcriptional regulator RamR ramR_T50P WP_000113609.1 genbank_protein_accession -> ACH50230.1 product_name TetR/AcrR family transcriptional regulator -> TetR/AcrR family transcriptional regulator RamR ramR_Y59H WP_000113609.1 genbank_protein_accession -> ACH50230.1 product_name TetR/AcrR family transcriptional regulator -> TetR/AcrR family transcriptional regulator RamR rpoB_H526Y WP_000263098.1 genbank_protein_accession -> CSN35596.1 product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB rpoB_L533P WP_000263098.1 genbank_protein_accession -> CSN35596.1 product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB rpoB_P564L WP_000263098.1 genbank_protein_accession -> CSN35596.1 product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB rpoB_Q513L WP_000263098.1 genbank_protein_accession -> CSN35596.1 product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB rpoB_Q513P WP_000263098.1 genbank_protein_accession -> CSN35596.1 product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB rpoB_R529C WP_000263098.1 genbank_protein_accession -> CSN35596.1 product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB rpoB_R529S WP_000263098.1 genbank_protein_accession -> CSN35596.1 product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB rpoB_R687H WP_000263098.1 genbank_protein_accession -> CSN35596.1 product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB rpoB_S531F WP_000263098.1 genbank_protein_accession -> CSN35596.1 product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB rpoB_T563P WP_000263098.1 genbank_protein_accession -> CSN35596.1 product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB rpoB_V146F WP_000263098.1 genbank_protein_accession -> CSN35596.1 product_name DNA-directed RNA polymerase subunit beta -> DNA-directed RNA polymerase subunit beta RpoB rpsL_K43R WP_057042458.1 genbank_protein_accession -> EAI0845362.1 product_name 30S ribosomal protein S12 -> 30S ribosomal protein S12 RpsL rpsL_K88E WP_057042458.1 genbank_protein_accession -> EAI0845362.1 product_name 30S ribosomal protein S12 -> 30S ribosomal protein S12 RpsL rpsL_K88Q WP_057042458.1 genbank_protein_accession -> EAI0845362.1 product_name 30S ribosomal protein S12 -> 30S ribosomal protein S12 RpsL rpsL_K88R WP_057042458.1 genbank_protein_accession -> EAI0845362.1 product_name 30S ribosomal protein S12 -> 30S ribosomal protein S12 RpsL soxR_G121D WP_000412428.1 genbank_protein_accession -> AAC77033.1 soxR_G121D WP_000412686.1 genbank_protein_accession -> CAD09250.1 soxR_R20H WP_000412428.1 genbank_protein_accession -> AAC77033.1 soxR_R20H WP_000412686.1 genbank_protein_accession -> CAD09250.1 soxS_A12S WP_000019358.1 genbank_protein_accession -> AAC77032.1 soxS_E52K WP_000019483.1 genbank_protein_accession -> AAL23089.1 tufA_A376S WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_A376T WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_A376V WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_E379K WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_G317D WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_L121Q WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_Q125E WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_Q125K WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_Q125R WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_Q330H WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_R231C WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_R231V WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_R234F WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_R234S WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_R334C WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_T335A WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_Y161C WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_Y161D WP_000031783.1 genbank_protein_accession -> AAC76364.1 tufA_Y161N WP_000031783.1 genbank_protein_accession -> AAC76364.1 uhpA_G97D WP_000633668.1 genbank_protein_accession -> CDJ73205.1 product_name DNA-binding response regulator -> DNA-binding response regulator UhpA uhpT_E350Q WP_000879194.1 genbank_protein_accession -> CDJ73208.1 product_name hexose phosphate transporter -> hexose phosphate transporter UhpT - AMR HMM library Changes: Total: Added 2 Total: Prev. Release 618 Total: Removed 0 Total: This Release 620 HMM Added: NF037973.1 myrA-NCBI HMM Added: NF038003.1 blaPLA_ORN_TER-NCBI HMM Modified: NF000389.2 blaPLA_ORN_TER-NCBI updated to NF000389.2 blaPFM-NCBI HMM Modified: NF033560.1 myrA-NCBI updated to NF033560.1 metallo_SslE-NCBI - Protein family changes: Total: Added 3 Total: Prev. Release 1527 Total: Removed 0 Total: This Release 1530 Family Added: - blaOKP-C Family Added: - blaOKP-D Family Added: NF037973.1 sslE Family Changed: - blaPFM updated to NF038003.1 blaPFM --------------------------------------------------------------------- Changes included in 2019-10-30.1 --------------------------------------------------------------------- This update includes backward incompatible changes to the AMRFinderPlus database format. It is compatible with AMRFinderPlus version 3.2 and above. To use this database version please update to AMRFinderPlus version 3.2. See https://github.com/ncbi/amr/wiki/Upgrading for how to upgrade and https://github.com/evolarjun/amr/wiki/AMRFinderPlus-database for information on the new database format. --organism / -O value Vibrio has been changed to Vibrio_cholerae because the blacklisted genes are common only in Vibrio_cholerae. Two erronious proteins have been removed, several HMMs have been added, and many new AMR alleles and "plus" genes. All HMM's have internal short names that have been changed to include a suffix to indicate the source (e.g., NCBI, Resfams, TIGRFAMs). Class and subclass have been defined for some parent families where they were not before. These will only be visible in AMRFinderPlus results if there was a novel sequence classified by AMRFinder above the level of the gene included in the Reference Gene Catalog. - Protein and point mutation changes: Total in prev: 6271 Total in release: 6443 Removed: 2 Added: 174 Changed: 42 Removed ltcA CAA23532.1 Removed sdeA EEZ94110.1 Added bmaE AAA23523.1 Added papG-II AAA24293.1 Added focG AAB20438.1 Added cdtA AAF81760.1 Added ibeA AAF98391.2 Added iutA AAN45165.2 Added sdeA AAS55383.1 Added emrD ACN65732.1 Added tcdR AJP10335.1 Added tcdB AJP10336.1 Added tcdE AJP10337.1 Added tcdA AJP10339.1 Added tcdC AJP10340.1 Added sfaF ASJ31253.1 Added emrD BAE77620.1 Added papG-III CAA43558.1 Added papA CAA43562.1 Added papH CAA43563.1 Added papC CAA43564.1 Added papE CAA43568.1 Added papG-I CAA43570.1 Added afaC CAA54117.1 Added afaC CAW30799.1 Added cdtB CBE05858.1 Added emrD EFF04178.1 Added sfaF EIL44824.1 Added papA ENA25238.1 Added cvaC P22522.1 Added mepA Q7A7N0.1 Added blaOXA-856 WP_001021774.1 Added blaOXA-847 WP_010793618.1 Added blaOXA-851 WP_014603442.1 Added tva(B) WP_014936356.1 Added blaOXA-848 WP_019485147.1 Added mcr-10.1 WP_023332837.1 Added blaADC-212 WP_031975357.1 Added blaADC-203 WP_032000414.1 Added blaOXA-855 WP_032061328.1 Added blaACT-74 WP_032652275.1 Added blaOXA-846 WP_033989974.1 Added blaOXA-850 WP_034006563.1 Added blaADC-215 WP_039098799.1 Added blaADC-216 WP_039211240.1 Added blaADC-219 WP_039213353.1 Added blaAQU-1 WP_042888870.1 Added blaLEN-32 WP_043875313.1 Added blaACT-75 WP_045347148.1 Added blaCMY-137 WP_053390271.1 Added blaADC-214 WP_060454527.1 Added blaADC-217 WP_060470109.1 Added blaLEN-42 WP_061154665.1 Added fosA8 WP_063277905.1 Added blaLEN-34 WP_072124806.1 Added blaLEN-43 WP_074385924.1 Added blaADC-218 WP_078216190.1 Added blaADC-213 WP_078230092.1 Added blaLEN-30 WP_080923375.1 Added blaAXC-3 WP_081330264.1 Added blaOXA-842 WP_087088911.1 Added blaADC-220 WP_087876534.1 Added blaLEN-55 WP_094917017.1 Added blaAXC-2 WP_100505522.1 Added blaLEN-41 WP_100675621.1 Added blaLEN-12 WP_110196444.1 Added blaOXA-854 WP_114158997.1 Added blaADC-199 WP_114166683.1 Added blaOXA-853 WP_114252036.1 Added blaLEN-58 WP_117122976.1 Added blaLEN-51 WP_123836928.1 Added blaACT-76 WP_126817982.1 Added blaADC-207 WP_130173437.1 Added blaADC-194 WP_133972424.1 Added blaOXA-822 WP_133973918.1 Added blaPDC-319 WP_134254706.1 Added blaLEN-39 WP_136026639.1 Added blaLEN-40 WP_136049560.1 Added blaLEN-38 WP_136086342.1 Added blaPDC-322 WP_138403314.1 Added blaOXA-894 WP_144376393.1 Added blaADC-197 WP_150823452.1 Added blaADC-198 WP_150823453.1 Added blaADC-200 WP_150823454.1 Added blaADC-201 WP_150823455.1 Added blaADC-202 WP_150823456.1 Added blaADC-204 WP_150823457.1 Added blaADC-205 WP_150823458.1 Added blaADC-206 WP_150823459.1 Added blaADC-208 WP_150823460.1 Added blaADC-209 WP_150823461.1 Added blaADC-210 WP_150823462.1 Added blaADC-211 WP_150823463.1 Added blaAXC-4 WP_150823464.1 Added blaAXC-5 WP_150823465.1 Added blaCARB-51 WP_150823466.1 Added blaCARB-52 WP_150823467.1 Added blaEBR-3 WP_150823468.1 Added blaIMP-65 WP_150823469.1 Added blaOXA-838 WP_150823470.1 Added blaOXA-839 WP_150823471.1 Added blaOXA-840 WP_150823472.1 Added blaOXA-841 WP_150823473.1 Added blaOXA-843 WP_150823474.1 Added blaOXA-844 WP_150823475.1 Added blaOXA-845 WP_150823476.1 Added blaOXA-849 WP_150823477.1 Added blaPDC-318 WP_150823478.1 Added blaPDC-320 WP_150823479.1 Added blaPDC-321 WP_150823480.1 Added blaPDC-323 WP_150823481.1 Added blaPDC-324 WP_150823482.1 Added blaPDC-325 WP_150823483.1 Added blaPDC-326 WP_150823484.1 Added blaPDC-327 WP_150823485.1 Added blaPDC-328 WP_150823486.1 Added blaPDC-329 WP_150823487.1 Added blaPDC-330 WP_150823488.1 Added blaPDC-331 WP_150823489.1 Added blaPDC-332 WP_150823490.1 Added blaPDC-384 WP_150823491.1 Added blaPDC-385 WP_150823492.1 Added blaPDC-386 WP_150823493.1 Added blaPST-2 WP_150823494.1 Added blaTEM-240 WP_150823495.1 Added mcr-3.28 WP_150823496.1 Added mcr-8.3 WP_150823497.1 Added tva(A) WP_151874537.1 Added blaACT-73 WP_152315464.1 Added blaIMP-85 WP_152315465.1 Added blaMIR-23 WP_152315466.1 Added blaNDM-25 WP_152315467.1 Added blaOXA-830 WP_152315468.1 Added blaOXA-852 WP_152315469.1 Added blaOXA-857 WP_152315470.1 Added blaOXA-858 WP_152315471.1 Added blaOXA-859 WP_152315472.1 Added blaOXA-860 WP_152315473.1 Added blaOXA-861 WP_152315474.1 Added blaOXA-862 WP_152315475.1 Added blaOXA-863 WP_152315476.1 Added blaOXA-864 WP_152315477.1 Added blaOXA-865 WP_152315478.1 Added blaOXA-866 WP_152315479.1 Added blaOXA-867 WP_152315480.1 Added blaOXA-868 WP_152315481.1 Added blaOXA-869 WP_152315482.1 Added blaOXA-870 WP_152315483.1 Added blaOXA-871 WP_152315484.1 Added blaOXA-872 WP_152315485.1 Added blaOXA-873 WP_152315486.1 Added blaOXA-874 WP_152315487.1 Added blaOXA-875 WP_152315488.1 Added blaOXA-876 WP_152315489.1 Added blaOXA-877 WP_152315490.1 Added blaOXA-878 WP_152315491.1 Added blaOXA-879 WP_152315492.1 Added blaOXA-880 WP_152315493.1 Added blaOXA-881 WP_152315494.1 Added blaOXA-882 WP_152315495.1 Added blaOXA-883 WP_152315496.1 Added blaOXA-884 WP_152315497.1 Added blaOXA-885 WP_152315498.1 Added blaOXA-886 WP_152315499.1 Added blaOXA-887 WP_152315500.1 Added blaOXA-888 WP_152315501.1 Added blaOXA-889 WP_152315502.1 Added blaOXA-890 WP_152315503.1 Added blaOXA-891 WP_152315504.1 Added blaOXA-892 WP_152315505.1 Added blaPDC-387 WP_152315506.1 Added blaPDC-388 WP_152315507.1 Added blaLEN-35 WP_152330887.1 Added blaLEN-36 WP_152330888.1 Added blaLEN-37 WP_152330889.1 Added blaSHV-4 WP_152330890.1 Changes: arsB AAA21095.1 blacklisted_taxa -> Escherichia arsC AAB09628.1 blacklisted_taxa -> Escherichia ymgB AAC74250.1 subclass ACID -> subtype BIOCIDE -> ACID emrD3 ABQ18953.1 blacklisted_taxa Vibrio -> Vibrio_cholerae arsB BAA24823.1 blacklisted_taxa -> Escherichia fieF BAB89353.1 blacklisted_taxa -> Klebsiella aac(6')-I WP_002289795.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_002293569.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_002293989.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_002328174.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_002339746.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_002373947.1 gene_family aac(6') -> aac(6')-I aac(6')-Iih WP_005880220.1 gene_family aac(6') -> aac(6')-I aac(6')-Ii WP_008265821.1 gene_family aac(6') -> aac(6')-I aac(6')-Iid WP_010720790.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_010723742.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_010727362.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_010728104.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_010736157.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_010737153.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_010750427.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_010752789.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_010768325.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_016172918.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_016177698.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_016628216.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_019722502.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_023519215.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_024635824.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_034688908.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_034700626.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_034860925.1 gene_family aac(6') -> aac(6')-I blaOXA-252 WP_037428895.1 curated_refseq_start Yes -> No genbank_cds_start 842113 -> 2724286 genbank_cds_stop 842910 -> 2725083 genbank_nucleotide_accession JTLE01000094.1 -> CP022089.2 genbank_protein_accession -> ASF15667.1 genbank_strand_orientation + -> - refseq_nucleotide_accession NG_050608.1 -> NG_066509.1 aac(6')-I WP_048603867.1 gene_family aac(6') -> aac(6')-I aac(6')-I WP_053766315.1 gene_family aac(6') -> aac(6')-I blaOXA-539 WP_071593233.1 product_name OXA-2 family class D extended-spectrum beta-lactamase OXA-539 -> OXA-2 family inhibitor-resistant class D extended-spectrum beta-lactamase OXA-539 subclass BETA-LACTAM -> CEPHALOSPORIN lnu(F) WP_071846285.1 allele linH2 -> aac(6')-I WP_071846353.1 gene_family aac(6') -> aac(6')-I blaOXA-576 WP_087696200.1 curated_refseq_start Yes -> No genbank_cds_start 843910 -> 1 genbank_cds_stop 844656 -> 747 genbank_nucleotide_accession NFPA01000015.1 -> MH085550.1 genbank_protein_accession -> AWD39715.1 refseq_nucleotide_accession NG_057458.1 -> NG_066510.1 blaAQU WP_099156042.1 allele blaAQU-1 -> product_name class C beta-lactamase AQU-1 -> AQU family class C beta-lactamase blaKPC-40 WP_115470049.1 product_name carbapenem-hydrolyzing class A beta-lactamase KPC-40 -> inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-40 blaOXA-681 WP_122630881.1 product_name OXA-2 family class D beta-lactamase OXA-681 -> OXA-2 family inhibitor-resistant class D extended-spectrum beta-lactamase OXA-681 subclass BETA-LACTAM -> CEPHALOSPORIN - AMR HMM library Changes: Total: Added 10 Total: Prev. Release 608 Total: Removed 0 Total: This Release 618 HMM Added: 154989_fosA-NCBI HMM Added: NF000252.1 MsrSA-NCBI HMM Added: NF000282.2 RPH_KJ151292.1-NCBI HMM Added: NF000315.1 amicyc_ac_ApmA-NCBI HMM Added: NF028537.1 QacCGHJ-NCBI HMM Added: NF033086.2 penta_rpt_QnrA-NCBI HMM Added: NF033134.0 cmlB1_MFS-NCBI HMM Added: NF033643.1 FOX-MOX-NCBI HMM Added: NF033651.1 dipept_VanX-NCBI HMM Added: NF033653.1 blaOXA-274_like-NCBI HMM Modified: NF000004.1 vanH-D updated to NF000004.1 vanH-Sc-NCBI HMM Modified: NF000005.4 ble_BLMT updated to NF000005.4 ble_MBL-NCBI HMM Modified: NF000006.2 trim_DfrA26 updated to NF000006.2 trim_DfrA3-NCBI HMM Modified: NF000007.1 16S_rRNA_Rmt_D updated to NF000007.1 16S_rRNA_Rmt_E-NCBI HMM Modified: NF000008.1 trim_DfrA1_rpt updated to NF000008.1 trim_DfrA20-NCBI HMM Modified: NF000009.1 tet_MFS_Tcr3 updated to NF000009.1 tet_MFS_V-NCBI HMM Modified: NF000010.1 AAC_2p_Ib updated to NF000010.1 AAC_2p_Ic-NCBI HMM Modified: NF000011.2 APH_6_Ic updated to NF000011.2 APH_6_Ic_gen-NCBI HMM Modified: NF000012.1 trim_DfrI updated to NF000012.1 vanH-Ac1-NCBI HMM Modified: NF000013.1 tet_NaH_anti_35 updated to NF000013.1 tet_destruct-NCBI HMM Modified: NF000014.1 tet_prtrans_34 updated to NF000014.1 tet_redox_37-NCBI HMM Modified: NF000015.3 APH_2pp_IIa updated to NF000015.3 APH_2pp_I_a_f_h-NCBI HMM Modified: NF000016.1 AAC_6p_Im updated to NF000016.1 AAC_6p_Ip-NCBI HMM Modified: NF000017.1 linco_LnuD updated to NF000017.1 linco_LnuE-NCBI HMM Modified: NF000018.2 trim_DfrA10 updated to NF000018.2 trim_DfrA12-NCBI HMM Modified: NF000019.2 trim_DfrA3 updated to NF000019.2 trim_DfrA35-NCBI HMM Modified: NF000020.1 stregram_VatE updated to NF000020.1 stregram_VatF-NCBI HMM Modified: NF000021.4 AAC_6p_Serra updated to NF000021.4 AAC_6p_Steno-NCBI HMM Modified: NF000022.1 stregra_B_VgbA updated to NF000022.1 stregra_B_VgbB-NCBI HMM Modified: NF000023.1 qac_SMR_C updated to NF000023.1 qac_SMR_G-NCBI HMM Modified: NF000024.1 ErmS updated to NF000024.1 ErmV-NCBI HMM Modified: NF000025.1 MFS_efflux_tcmA updated to NF000025.1 MOX_CMY1_fam-NCBI HMM Modified: NF000026.1 154989_fosA updated to NF000026.1 156720500_bleO-NCBI HMM Modified: NF000027.1 156720500_bleO updated to NF000027.1 1567214_ble-NCBI HMM Modified: NF000028.1 1567214_ble updated to NF000028.1 16S_rRNA_NpmA-NCBI HMM Modified: NF000029.2 APH_9_Ib updated to NF000029.2 BlaA_Yent-NCBI HMM Modified: NF000030.1 16S_rRNA_NpmA updated to NF000030.1 16S_rRNA_Rmt_B-NCBI HMM Modified: NF000032.1 D_ala_D_ser_VanL updated to NF000032.1 D_ala_D_ser_VanN-NCBI HMM Modified: NF000033.1 vanT-L-mem updated to NF000033.1 vanW-B-NCBI HMM Modified: NF000034.1 AAC_2p_Ic updated to NF000034.1 AAC_2p_Id-NCBI HMM Modified: NF000035.1 nosihep_NshR updated to NF000035.1 penta_rpt_Qnr-NCBI HMM Modified: NF000036.1 D_ala_D_ser_VanE updated to NF000036.1 D_ala_D_ser_VanG-NCBI HMM Modified: NF000037.1 RND_perm_OqxB updated to NF000037.1 RND_permease_1-NCBI HMM Modified: NF000039.1 trim_DfrA18 updated to NF000039.1 trim_DfrA19-NCBI HMM Modified: NF000041.1 trim_DfrA19 updated to NF000041.1 trim_DfrA1_like-NCBI HMM Modified: NF000042.1 AAC_2p_Id updated to NF000042.1 AAC_2p_Ie-NCBI HMM Modified: NF000043.1 tet_MFS_P_a updated to NF000043.1 tet_MFS_Tcr3-NCBI HMM Modified: NF000044.2 APH_2pp_IIIa updated to NF000044.2 APH_2pp_IIa-NCBI HMM Modified: NF000047.1 ErmV updated to NF000047.1 EspJ_gen-NCBI HMM Modified: NF000048.1 AAC_6p_A40 updated to NF000048.1 AAC_6p_A48-NCBI HMM Modified: NF000049.1 tet_MFS_40 updated to NF000049.1 tet_MFS_42-NCBI HMM Modified: NF000050.2 AAC_6p_A29 updated to NF000050.2 AAC_6p_A30-NCBI HMM Modified: NF000051.1 macrolide_MefB updated to NF000051.1 macrolide_MefC-NCBI HMM Modified: NF000052.4 APH_9_Ia updated to NF000052.4 APH_9_Ib-NCBI HMM Modified: NF000053.2 trim_DfrA12 updated to NF000053.2 trim_DfrA13_A21-NCBI HMM Modified: NF000054.1 AAC_2p_Ie updated to NF000054.1 AAC_3-NCBI HMM Modified: NF000055.3 trim_DfrA13_A21 updated to NF000055.3 trim_DfrA18-NCBI HMM Modified: NF000056.3 penta_rpt_QnrS updated to NF000056.3 penta_rpt_QnrVC-NCBI HMM Modified: NF000059.1 tet_redox_37 updated to NF000059.1 toxin_EAST1-NCBI HMM Modified: NF000061.1 linco_LnuP updated to NF000061.1 lyase_MerB-NCBI HMM Modified: NF000062.1 ANT_6_str updated to NF000062.1 ANT_9-NCBI HMM Modified: NF000063.1 Fos_BSH_Sepi updated to NF000063.1 Fos_GSH-NCBI HMM Modified: NF000064.3 ANT_2pp_Ia updated to NF000064.3 ANT_3pp_AadA1-NCBI HMM Modified: NF000065.1 trim_DfrA3b updated to NF000065.1 trim_DfrA8-NCBI HMM Modified: NF000066.1 rifampin_ARR_Sa updated to NF000066.1 sat2-NCBI HMM Modified: NF000067.2 SMR_qac_FL updated to NF000067.2 SMR_qac_G2-NCBI HMM Modified: NF000069.1 16S_rRNA_Rmt_E updated to NF000069.1 16S_rRNA_Rmt_F-NCBI HMM Modified: NF000071.4 penta_rpt_QnrA updated to NF000071.4 penta_rpt_QnrAS-NCBI HMM Modified: NF000072.1 MFS_efflux_PexA updated to NF000072.1 MFS_efflux_tcmA-NCBI HMM Modified: NF000074.1 299782349_fosC updated to NF000074.1 299782351_fosA-NCBI HMM Modified: NF000075.1 299782351_fosA updated to NF000075.1 354827590_fosA-NCBI HMM Modified: NF000076.3 APH_2pp_Ie_IVa updated to NF000076.3 APH_2pp_If_Ih-NCBI HMM Modified: NF000077.1 Erm42 updated to NF000077.1 Erm43-NCBI HMM Modified: NF000079.1 ANT_4p_Ib updated to NF000079.1 ANT_6-NCBI HMM Modified: NF000084.1 amicyc_ac_ApmA updated to NF000084.1 arsB_Sta_pI258-NCBI HMM Modified: NF000085.1 Fos_BSH_Saur updated to NF000085.1 Fos_BSH_Sepi-NCBI HMM Modified: NF000086.1 vanY_far updated to NF000086.1 vanY_of_D-NCBI HMM Modified: NF000087.1 ErmO updated to NF000087.1 ErmS-NCBI HMM Modified: NF000088.1 viomycin_Vph updated to NF000088.1 zbmA-NCBI HMM Modified: NF000089.1 qac_MFS_AB updated to NF000089.1 qac_SMR_C-NCBI HMM Modified: NF000090.1 trans_reg_VanU updated to NF000090.1 transloc_TIR-NCBI HMM Modified: NF000091.3 D_ala_D_ser_VanG updated to NF000091.3 D_ala_D_ser_VanL-NCBI HMM Modified: NF000092.1 D_ala_D_lac_Ao2 updated to NF000092.1 D_ala_D_lac_Sc-NCBI HMM Modified: NF000093.1 D_ala_D_ser_VanN updated to NF000093.1 EreA-NCBI HMM Modified: NF000094.1 354827590_fosA updated to NF000094.1 47473_otr-NCBI HMM Modified: NF000095.1 tet_MFS_OtrB updated to NF000095.1 tet_MFS_P_a-NCBI HMM Modified: NF000096.1 stregra_B_VgbB updated to NF000096.1 stregram_VatA-NCBI HMM Modified: NF000097.1 stregram_VatC updated to NF000097.1 stregram_VatD-NCBI HMM Modified: NF000098.1 Fos_BSH_Bcer updated to NF000098.1 Fos_BSH_Saur-NCBI HMM Modified: NF000100.2 AAC_2p_IIa updated to NF000100.2 AAC_2p_IIb-NCBI HMM Modified: NF000101.1 stregram_VatA updated to NF000101.1 stregram_VatC-NCBI HMM Modified: NF000103.1 tet_ABC_AB_B updated to NF000103.1 tet_MFS_38-NCBI HMM Modified: NF000107.2 APH_4_Ia updated to NF000107.2 APH_6-NCBI HMM Modified: NF000108.1 AAC_2p_Ia updated to NF000108.1 AAC_2p_Ib-NCBI HMM Modified: NF000109.2 trim_DfrA9 updated to NF000109.2 trim_DfrB-NCBI HMM Modified: NF000110.2 AAC_6p_If updated to NF000110.2 AAC_6p_Il-NCBI HMM Modified: NF000111.1 stregram_VatD updated to NF000111.1 stregram_VatE-NCBI HMM Modified: NF000112.1 vanH-Amyco updated to NF000112.1 vanH-D-NCBI HMM Modified: NF000113.1 16S_rRNA_Rmt_F updated to NF000113.1 16S_rRNA_Rmt_G-NCBI HMM Modified: NF000114.1 16S_rRNA_Rmt_G updated to NF000114.1 16S_rRNA_Rmt_H-NCBI HMM Modified: NF000115.2 AAC_6p_Iad updated to NF000115.2 AAC_6p_Iak-NCBI HMM Modified: NF000116.1 16S_rRNA_Rmt_H updated to NF000116.1 16S_rRNA_Rmt_gen-NCBI HMM Modified: NF000118.3 AAC_6p_A31 updated to NF000118.3 AAC_6p_A34-NCBI HMM Modified: NF000119.1 linco_LnuF updated to NF000119.1 linco_LnuG-NCBI HMM Modified: NF000120.3 47473_otr updated to NF000120.3 485965_fosC-NCBI HMM Modified: NF000122.1 485965_fosC updated to NF000122.1 491618165_fosA-NCBI HMM Modified: NF000123.2 AAC_6p_A34 updated to NF000123.2 AAC_6p_A37-NCBI HMM Modified: NF000124.1 491618165_fosA updated to NF000124.1 498180014_fosA-NCBI HMM Modified: NF000125.1 498180014_fosA updated to NF000125.1 AAC_2p_IIa-NCBI HMM Modified: NF000126.2 trim_DfrA8 updated to NF000126.2 trim_DfrA9-NCBI HMM Modified: NF000127.2 trim_DfrA20 updated to NF000127.2 trim_DfrA23-NCBI HMM Modified: NF000128.1 vanH-Sc updated to NF000128.1 vanH_Agroup-NCBI HMM Modified: NF000129.1 D_ala_D_lac_Sc updated to NF000129.1 D_ala_D_lac_VanA-NCBI HMM Modified: NF000131.1 MATE_multi_MepA updated to NF000131.1 MATE_multi_NorM-NCBI HMM Modified: NF000132.2 APH_2pp_Ig updated to NF000132.2 APH_3p-NCBI HMM Modified: NF000133.1 Erm32 updated to NF000133.1 Erm37-NCBI HMM Modified: NF000134.2 trim_DfrA23 updated to NF000134.2 trim_DfrA24-NCBI HMM Modified: NF000135.2 AAC_6p_IIc updated to NF000135.2 AAC_6p_Ia_fam-NCBI HMM Modified: NF000137.2 APH_7pp_Ia updated to NF000137.2 APH_9_Ia-NCBI HMM Modified: NF000138.1 AAC_6p_Iz updated to NF000138.1 AAC_6p_Serra-NCBI HMM Modified: NF000139.2 penta_rpt_QnrD updated to NF000139.2 penta_rpt_QnrE-NCBI HMM Modified: NF000141.1 linco_LnuC updated to NF000141.1 linco_LnuD-NCBI HMM Modified: NF000142.1 vanZ-Pt updated to NF000142.1 viomycin_Vph-NCBI HMM Modified: NF000143.1 trim_DfrG updated to NF000143.1 trim_DfrI-NCBI HMM Modified: NF000144.1 D_ala_D_lac_VanF updated to NF000144.1 D_ala_D_lac_VanI-NCBI HMM Modified: NF000145.1 vanZ-F updated to NF000145.1 vanZ-Pt-NCBI HMM Modified: NF000146.2 trim_DfrA24 updated to NF000146.2 trim_DfrA26-NCBI HMM Modified: NF000147.1 stregram_VatF updated to NF000147.1 stregram_VatH-NCBI HMM Modified: NF000148.1 SMR_qac_pB8 updated to NF000148.1 Shiga_Stx1A-NCBI HMM Modified: NF000149.1 vanXY_G updated to NF000149.1 vanY_AFMPt-NCBI HMM Modified: NF000150.1 16S_rRNA_Rmt_C updated to NF000150.1 16S_rRNA_Rmt_D-NCBI HMM Modified: NF000151.1 vanH-Ac1 updated to NF000151.1 vanH-Amyco-NCBI HMM Modified: NF000152.2 AAC_6p_A37 updated to NF000152.2 AAC_6p_A40-NCBI HMM Modified: NF000153.1 linco_LnuAN2 updated to NF000153.1 linco_LnuB-NCBI HMM Modified: NF000154.1 macrolide_MefEN2 updated to NF000154.1 macrolide_MphA-NCBI HMM Modified: NF000155.1 trim_DfrC updated to NF000155.1 trim_DfrD-NCBI HMM Modified: NF000157.1 fusid_est_FusH updated to NF000157.1 glycotrans_Rgt-NCBI HMM Modified: NF000158.2 AAC_6p_Il updated to NF000158.2 AAC_6p_Im-NCBI HMM Modified: NF000159.1 trim_DfrD updated to NF000159.1 trim_DfrDGK-NCBI HMM Modified: NF000165.3 AAC_6p_Entco updated to NF000165.3 AAC_6p_IIc-NCBI HMM Modified: NF000166.1 ABCF_CarA updated to NF000166.1 ABCF_Lsa_all-NCBI HMM Modified: NF000167.1 ABCF_Lsa_all updated to NF000167.1 ABCF_Msr_all-NCBI HMM Modified: NF000168.1 ABCF_Msr_all updated to NF000168.1 ABCF_OptrA-NCBI HMM Modified: NF000169.1 ABCF_Sal updated to NF000169.1 ABCF_Vga_all-NCBI HMM Modified: NF000170.1 ABCF_Vga_all updated to NF000170.1 ABCF_producer-NCBI HMM Modified: NF000171.1 ABCF_producer updated to NF000171.1 ANT_2pp_Ia-NCBI HMM Modified: NF000181.1 ANT_4p_Ia updated to NF000181.1 ANT_4p_Ib-NCBI HMM Modified: NF000185.2 BlaEC updated to NF000185.2 BlaI_of_MRSA-NCBI HMM Modified: NF000186.1 BlaI_of_MRSA updated to NF000186.1 BlaMIR-NCBI HMM Modified: NF000187.3 BlaMIR updated to NF000187.3 BlmB-NCBI HMM Modified: NF000188.2 CARB updated to NF000188.2 CAR_gen_B3-NCBI HMM Modified: NF000191.1 CMY2 updated to NF000191.1 CfrAB-NCBI HMM Modified: NF000206.1 D_ala_D_lac updated to NF000206.1 D_ala_D_lac_Ao2-NCBI HMM Modified: NF000207.3 D_ala_D_ser updated to NF000207.3 D_ala_D_ser_VanC-NCBI HMM Modified: NF000208.1 EreA updated to NF000208.1 EreB-NCBI HMM Modified: NF000209.1 EreB updated to NF000209.1 EreD-NCBI HMM Modified: NF000216.2 blaFEZ updated to NF000216.2 blaFIM-NCBI HMM Modified: NF000218.1 FexA updated to NF000218.1 FloR-NCBI HMM Modified: NF000219.1 FloR updated to NF000219.1 FosA-NCBI HMM Modified: NF000221.4 FosA updated to NF000221.4 FosF-NCBI HMM Modified: NF000222.1 FosX updated to NF000222.1 Fos_BSH-NCBI HMM Modified: NF000224.3 AAC_6p_Acine updated to NF000224.3 AAC_6p_Entco-NCBI HMM Modified: NF000225.3 AAC_6p_Strep updated to NF000225.3 AAC_6p_Yersi-NCBI HMM Modified: NF000232.1 L2 updated to NF000232.1 LEN-NCBI HMM Modified: NF000233.2 LEN updated to NF000233.2 MATE_multi_MepA-NCBI HMM Modified: NF000235.3 linco_LnuB updated to NF000235.3 linco_LnuC-NCBI HMM Modified: NF000236.1 linco_LnuA updated to NF000236.1 linco_LnuAN2-NCBI HMM Modified: NF000237.1 MECA_PBP2A updated to NF000237.1 MECA_pure-NCBI HMM Modified: NF000239.3 MOX_CMY1_fam updated to NF000239.3 MPH_3-NCBI HMM Modified: NF000240.1 macrolide_MphC updated to NF000240.1 macrolide_MphE-NCBI HMM Modified: NF000241.1 MPH_3 updated to NF000241.1 MecI_of_mecA-NCBI HMM Modified: NF000242.1 macrolide_MphB updated to NF000242.1 macrolide_MphC-NCBI HMM Modified: NF000243.1 MecI_of_mecA updated to NF000243.1 MecI_of_mecC-NCBI HMM Modified: NF000244.1 MecI_of_mecC updated to NF000244.1 MerA-TIGRFAMs HMM Modified: NF000245.1 macrolide_MefA updated to NF000245.1 macrolide_MefB-NCBI HMM Modified: NF000246.1 macrolide_MefC updated to NF000246.1 macrolide_MefEN2-NCBI HMM Modified: NF000249.1 MexE updated to NF000249.1 MexX-Resfams HMM Modified: NF000254.1 macrolide_MphA updated to NF000254.1 macrolide_MphB-NCBI HMM Modified: NF000255.1 macrolide_MphF updated to NF000255.1 merT_RC607-NCBI HMM Modified: NF000256.1 MsrSA updated to NF000256.1 MupA-NCBI HMM Modified: NF000257.1 MupA updated to NF000257.1 MupB-NCBI HMM Modified: NF000258.1 MupB updated to NF000258.1 NimABCDEF-NCBI HMM Modified: NF000259.2 blaNDM updated to NF000259.2 blaOCH-NCBI HMM Modified: NF000261.1 NimABCDEF updated to NF000261.1 NimIJ-NCBI HMM Modified: NF000262.1 NimIJ updated to NF000262.1 NshR_TsnR-NCBI HMM Modified: NF000263.1 MATE_multi_NorM updated to NF000263.1 MECA1_pure-NCBI HMM Modified: NF000264.2 blaOCH updated to NF000264.2 blaOXA-10_like-NCBI HMM Modified: NF000265.2 OKP updated to NF000265.2 OqxA_adapt_sub-NCBI HMM Modified: NF000266.2 blaOXA-23_like updated to NF000266.2 blaOXA-24_like-NCBI HMM Modified: NF000267.2 blaOXA-2_like updated to NF000267.2 blaOXA-364_like-NCBI HMM Modified: NF000268.2 blaOXA-51_like updated to NF000268.2 blaOXA-55_like-NCBI HMM Modified: NF000269.2 blaOXA-213_like updated to NF000269.2 blaOXA-214_like-NCBI HMM Modified: NF000270.1 bla_class_D_alt updated to NF000270.1 bla_class_D_main-NCBI HMM Modified: NF000271.2 blaOXY updated to NF000271.2 blaP-NCBI HMM Modified: NF000272.1 OqxA_adapt_sub updated to NF000272.1 PRK10026.1-PRKfam HMM Modified: NF000275.2 blaPLA_ORN_TER updated to NF000275.2 blaPME-NCBI HMM Modified: NF000276.2 SMR_qac_E updated to NF000276.2 SMR_qac_FL-NCBI HMM Modified: NF000277.1 qac_SMR_G updated to NF000277.1 qac_SMR_H-NCBI HMM Modified: NF000278.1 SMR_qac_G2 updated to NF000278.1 SMR_qac_K-NCBI HMM Modified: NF000279.1 qac_SMR_H updated to NF000279.1 qac_SMR_J-NCBI HMM Modified: NF000280.1 SMR_efflux_smr updated to NF000280.1 SMR_qac_E-NCBI HMM Modified: NF000283.1 RPH_KJ151292.1 updated to NF000283.1 RTG-NCBI HMM Modified: NF000284.1 RTG updated to NF000284.1 SHV-NCBI HMM Modified: NF000285.3 SHV updated to NF000285.3 SHV_LEN_OKP-NCBI HMM Modified: NF000287.1 SMB1_fam updated to NF000287.1 SMR_efflux_smr-NCBI HMM Modified: NF000294.1 Sul1 updated to NF000294.1 Sul2-NCBI HMM Modified: NF000295.1 Sul2 updated to NF000295.1 Sul3-NCBI HMM Modified: NF000296.1 Sul3 updated to NF000296.1 Sul4-NCBI HMM Modified: NF000298.2 blaTLA updated to NF000298.2 blaTMB-NCBI HMM Modified: NF000311.1 Vat_ABCDEFH updated to NF000311.1 aadE-Cc-NCBI HMM Modified: NF000312.1 ANT_6_aadK updated to NF000312.1 ANT_6_aadS-NCBI HMM Modified: NF000318.1 rifampin_ARR_Ms updated to NF000318.1 rifampin_ARR_Sa-NCBI HMM Modified: NF000320.2 betalact_A_Burk_PenA updated to NF000320.2 betalact_A_Burk_PenI-NCBI HMM Modified: NF000321.2 betalact_A_Burk_PenI updated to NF000321.2 bla-A_Chryseo-NCBI HMM Modified: NF000322.2 blaCcrA updated to NF000322.2 blaDHA-NCBI HMM Modified: NF000323.2 blaFONA updated to NF000323.2 blaFOX-NCBI HMM Modified: NF000324.2 blaLUT updated to NF000324.2 blaMCA-NCBI HMM Modified: NF000326.1 blaR1_generic updated to NF000326.1 blaRCP-NCBI HMM Modified: NF000327.2 blaSCO updated to NF000327.2 blaSED-NCBI HMM Modified: NF000328.2 blaSED updated to NF000328.2 blaSFH-NCBI HMM Modified: NF000329.2 bla_B2_CphA updated to NF000329.2 bla_Bc_2-NCBI HMM Modified: NF000330.1 trim_DfrA1_like updated to NF000330.1 trim_DfrA1_rpt-NCBI HMM Modified: NF000331.1 trim_DfrB updated to NF000331.1 trim_DfrC-NCBI HMM Modified: NF000332.1 trim_DfrDGK updated to NF000332.1 trim_DfrE-NCBI HMM Modified: NF000333.1 trim_DfrF updated to NF000333.1 trim_DfrG-NCBI HMM Modified: NF000336.1 emrE updated to NF000336.1 erm_38_23S_MT-NCBI HMM Modified: NF000337.1 erm_SHROVE updated to NF000337.1 fomA_AB016934.1.gene6-NCBI HMM Modified: NF000338.1 fomA_AB016934.1.gene6 updated to NF000338.1 fos-Crono-NCBI HMM Modified: NF000339.2 fos-Crono updated to NF000339.2 fosA7-NCBI HMM Modified: NF000340.1 fusB updated to NF000340.1 fusC-NCBI HMM Modified: NF000341.1 fusC updated to NF000341.1 fusD-NCBI HMM Modified: NF000343.1 rif_mono_Iri updated to NF000343.1 rif_monoox-NCBI HMM Modified: NF000354.1 glycotrans_Rgt updated to NF000354.1 intimin_all-NCBI HMM Modified: NF000355.3 ribo_prot_ABC_F updated to NF000355.3 rif_mono_Iri-NCBI HMM Modified: NF000358.1 sat2 updated to NF000358.1 sat3-NCBI HMM Modified: NF000359.1 sat3 updated to NF000359.1 sat4-NCBI HMM Modified: NF000360.1 sat4 updated to NF000360.1 self_FomB_kinase-NCBI HMM Modified: NF000361.1 self_FomB_kinase updated to NF000361.1 self_GT_OleI-NCBI HMM Modified: NF000362.1 self_GT_OleI updated to NF000362.1 self_KamB-NCBI HMM Modified: NF000363.1 self_KamB updated to NF000363.1 sensor_BlaR1-NCBI HMM Modified: NF000371.1 vanH_Agroup updated to NF000371.1 vanH_gen-NCBI HMM Modified: NF000372.1 D_ala_D_lac_VanI updated to NF000372.1 D_ala_D_lac_VanM-NCBI HMM Modified: NF000373.1 vanJ updated to NF000373.1 vanR-A-NCBI HMM Modified: NF000374.1 D_ala_D_lac_VanO updated to NF000374.1 D_ala_D_ser-NCBI HMM Modified: NF000380.1 vanXY updated to NF000380.1 vanXY_G-NCBI HMM Modified: NF000383.2 blaLAP updated to NF000383.2 blaLHK-NCBI HMM Modified: NF000384.1 QacCGHJ updated to NF000384.1 RND_adapt_MexA-NCBI HMM Modified: NF000385.4 blaACT updated to NF000385.4 blaADC-NCBI HMM Modified: NF000386.2 blaOXA-10_like updated to NF000386.2 blaOXA-114_like-NCBI HMM Modified: NF000387.2 blaOXA-48_like updated to NF000387.2 blaOXA-493_like-NCBI HMM Modified: NF000388.2 blaOXA-1_like updated to NF000388.2 blaOXA-211_like-NCBI HMM Modified: NF000389.2 blaPER updated to NF000389.2 blaPLA_ORN_TER-NCBI HMM Modified: NF000390.2 blaVEB updated to NF000390.2 blaVIM-NCBI HMM Modified: NF000395.3 blaOXA-60_like updated to NF000395.3 blaOXA-61_like-NCBI HMM Modified: NF000396.2 blaGIM updated to NF000396.2 blaGOB-NCBI HMM Modified: NF000397.2 blaACC updated to NF000397.2 blaACI-NCBI HMM Modified: NF000398.2 blaBEL updated to NF000398.2 blaBES-NCBI HMM Modified: NF000399.2 blaFOX updated to NF000399.2 blaFRI-NCBI HMM Modified: NF000400.2 blaIMI updated to NF000400.2 blaIMP-NCBI HMM Modified: NF000401.1 vanR-A updated to NF000401.1 vanR-B-NCBI HMM Modified: NF000402.1 vanR-B updated to NF000402.1 vanR-C-NCBI HMM Modified: NF000403.1 vanR-C updated to NF000403.1 vanR-D-NCBI HMM Modified: NF000404.1 vanR-D updated to NF000404.1 vanR-O-NCBI HMM Modified: NF000405.1 HARLDQ_not_B3 updated to NF000405.1 HK_VanS_ACDEFG-NCBI HMM Modified: NF000406.1 MECB_PBP updated to NF000406.1 MECC_PBP-NCBI HMM Modified: NF000407.1 MECC_PBP updated to NF000407.1 MECD_PBP-NCBI HMM Modified: NF000408.1 MECA2_pure updated to NF000408.1 MECA_PBP2A-NCBI HMM Modified: NF000409.1 MECA_pure updated to NF000409.1 MECB_PBP-NCBI HMM Modified: NF000410.1 MECA1_pure updated to NF000410.1 MECA2_pure-NCBI HMM Modified: NF000411.1 Erm45 updated to NF000411.1 ErmO-NCBI HMM Modified: NF000412.1 Erm43 updated to NF000412.1 Erm45-NCBI HMM Modified: NF000413.2 blaBKC updated to NF000413.2 blaBKC_GPC-NCBI HMM Modified: NF000414.2 blaPME updated to NF000414.2 blaPOM-NCBI HMM Modified: NF000415.2 blaOXA-372_like updated to NF000415.2 blaOXA-46_like-NCBI HMM Modified: NF000417.2 blaOXA-211_like updated to NF000417.2 blaOXA-213_like-NCBI HMM Modified: NF000418.2 blaOXA-214_like updated to NF000418.2 blaOXA-229_like-NCBI HMM Modified: NF000419.2 blaCMH updated to NF000419.2 blaCPS-NCBI HMM Modified: NF000420.1 penta_rpt_QnrB updated to NF000420.1 penta_rpt_QnrC-NCBI HMM Modified: NF000421.1 penta_rpt_QnrVC updated to NF000421.1 phenyl_MerG-NCBI HMM Modified: NF000422.6 blaPDC updated to NF000422.6 blaPDC_var-NCBI HMM Modified: NF000423.2 blaSRT updated to NF000423.2 blaTEM-NCBI HMM Modified: NF000424.3 CfrAB updated to NF000424.3 D_ala_D_lac-NCBI HMM Modified: NF000425.2 blaADC updated to NF000425.2 blaAFM-NCBI HMM Modified: NF000426.2 blaSIM updated to NF000426.2 blaSME-NCBI HMM Modified: NF000427.2 blaCAU updated to NF000427.2 blaCBP-NCBI HMM Modified: NF000428.4 blaFRI updated to NF000428.4 blaFTU-NCBI HMM Modified: NF000429.2 blaOXA-63_like updated to NF000429.2 blaOXA-727_like-NCBI HMM Modified: NF000430.2 blaOXA-62_like updated to NF000430.2 blaOXA-63_like-NCBI HMM Modified: NF000431.1 AAC_6p_Ian updated to NF000431.1 AAC_6p_Ib-NCBI HMM Modified: NF000432.2 blaOXA-50_like updated to NF000432.2 blaOXA-51_like-NCBI HMM Modified: NF000434.2 blaOXA-24_like updated to NF000434.2 blaOXA-266_fam-NCBI HMM Modified: NF000435.2 blaOXA-61_like updated to NF000435.2 blaOXA-62_like-NCBI HMM Modified: NF000436.2 blaOXA-134_like updated to NF000436.2 blaOXA-143_like-NCBI HMM Modified: NF000437.2 blaFIM updated to NF000437.2 blaFONA-NCBI HMM Modified: NF000438.2 blaPOM updated to NF000438.2 blaPST-NCBI HMM Modified: NF000439.2 blaAIM updated to NF000439.2 blaALI-NCBI HMM Modified: NF000440.2 blaTHIN updated to NF000440.2 blaTLA-NCBI HMM Modified: NF000441.2 blaMUS updated to NF000441.2 blaNDM-NCBI HMM Modified: NF000442.2 blaTUS updated to NF000442.2 blaVCC-NCBI HMM Modified: NF000443.2 blaTMB updated to NF000443.2 blaTTU-NCBI HMM Modified: NF000444.2 blaEBR updated to NF000444.2 blaESP-1_fam-NCBI HMM Modified: NF000445.2 blaDIM updated to NF000445.2 blaDIM_SIM_IMP-NCBI HMM Modified: NF000446.2 blaCIA updated to NF000446.2 blaCMA-NCBI HMM Modified: NF000447.2 bla-A_Chryseo updated to NF000447.2 bla-B1-FLAV-NCBI HMM Modified: NF000448.2 blaACI updated to NF000448.2 blaACT-NCBI HMM Modified: NF000449.2 blaBIC updated to NF000449.2 blaBJP-NCBI HMM Modified: NF000450.2 bla-B1-FLAV updated to NF000450.2 bla1-NCBI HMM Modified: NF000451.2 blaBES updated to NF000451.2 blaBIC-NCBI HMM Modified: NF000452.2 blaKLUC updated to NF000452.2 blaKPC-NCBI HMM Modified: NF000453.2 blaPEDO-3_fam updated to NF000453.2 blaPER-NCBI HMM Modified: NF000454.2 blaCPS updated to NF000454.2 blaCRH-NCBI HMM Modified: NF000455.2 blaESP-1_fam updated to NF000455.2 blaFEZ-NCBI HMM Modified: NF000456.2 blaMSI-1_fam updated to NF000456.2 blaMUS-NCBI HMM Modified: NF000457.2 blaPEDO-1_fam updated to NF000457.2 blaPEDO-2_fam-NCBI HMM Modified: NF000458.2 blaPEDO-2_fam updated to NF000458.2 blaPEDO-3_fam-NCBI HMM Modified: NF000459.2 blaSPG-1_fam updated to NF000459.2 blaSPM-NCBI HMM Modified: NF000460.1 fusD updated to NF000460.1 fusF-NCBI HMM Modified: NF000461.2 blaOXA-184_like updated to NF000461.2 blaOXA-1_like-NCBI HMM Modified: NF000462.2 blaOXA-493_like updated to NF000462.2 blaOXA-50_like-NCBI HMM Modified: NF000463.2 blaOXA_Campylobacter updated to NF000463.2 blaOXY-NCBI HMM Modified: NF000464.2 blaOXA-143_like updated to NF000464.2 blaOXA-184_like-NCBI HMM Modified: NF000465.1 polymyxin_MCR1 updated to NF000465.1 polymyxin_MCR2-NCBI HMM Modified: NF000466.2 16S_rRNA_Rmt_gen updated to NF000466.2 299782349_fosC-NCBI HMM Modified: NF000467.1 FosG updated to NF000467.1 FosK-NCBI HMM Modified: NF000468.1 Erm37 updated to NF000468.1 Erm42-NCBI HMM Modified: NF000469.2 CAR_gen_B3 updated to NF000469.2 CHL_hydrolase-NCBI HMM Modified: NF000470.1 D_ala_D_lac_VanM updated to NF000470.1 D_ala_D_lac_VanO-NCBI HMM Modified: NF000471.1 vanY_of_D updated to NF000471.1 vanZ-A-NCBI HMM Modified: NF000472.1 vanY_AFMPt updated to NF000472.1 vanY_BG-NCBI HMM Modified: NF000473.1 vanY_BG updated to NF000473.1 vanY_far-NCBI HMM Modified: NF000474.1 tet_ABC_46_A updated to NF000474.1 tet_ABC_46_B-NCBI HMM Modified: NF000475.1 tet_ABC_46_B updated to NF000475.1 tet_ABC_AB_A-NCBI HMM Modified: NF000476.1 myrA updated to NF000476.1 nosihep_NshR-NCBI HMM Modified: NF000477.1 NshR_TsnR updated to NF000477.1 OKP-NCBI HMM Modified: NF000478.2 linco_LnuE updated to NF000478.2 linco_LnuF-NCBI HMM Modified: NF000479.1 zbmA updated to NF000479.1 HMM Modified: NF000480.2 PSE updated to NF000480.2 P_eth_NH2_trans-NCBI HMM Modified: NF000481.1 carbeni_gen updated to NF000481.1 chaper_CopP-NCBI HMM Modified: NF000482.1 AAC_3_XI updated to NF000482.1 AAC_6p_A10-NCBI HMM Modified: NF000483.1 BlmB updated to NF000483.1 CARB-NCBI HMM Modified: NF000485.1 TlmB updated to NF000485.1 VanC1_ser_lig-NCBI HMM Modified: NF000486.1 AAC_6p_Ip updated to NF000486.1 AAC_6p_Iz-NCBI HMM Modified: NF000487.1 stat updated to NF000487.1 stregra_B_VgbA-NCBI HMM Modified: NF000488.1 chrB updated to NF000488.1 classA_carba-NCBI HMM Modified: NF000489.1 ble_Sh updated to NF000489.1 carbeni_gen-NCBI HMM Modified: NF000490.1 chloram_CatB updated to NF000490.1 chrB-NCBI HMM Modified: NF000491.1 chloram_CatA updated to NF000491.1 chloram_CatB-NCBI HMM Modified: NF000492.1 vanH_gen updated to NF000492.1 vanJ-NCBI HMM Modified: NF000493.1 Fos_BSH updated to NF000493.1 Fos_BSH_Bcer-NCBI HMM Modified: NF000494.1 FosF updated to NF000494.1 FosG-NCBI HMM Modified: NF000495.1 FosK updated to NF000495.1 FosL-NCBI HMM Modified: NF000496.1 Fos_GSH updated to NF000496.1 HARLDQ_not_B3-NCBI HMM Modified: NF000497.1 AAC_6p_Iak updated to NF000497.1 AAC_6p_Ian-NCBI HMM Modified: NF000498.2 APH_2pp_If_Ih updated to NF000498.2 APH_2pp_Ig-NCBI HMM Modified: NF000499.1 Erm23S_rRNA_broad updated to NF000499.1 Erm32-NCBI HMM Modified: NF000500.2 blaOXA-58_like updated to NF000500.2 blaOXA-60_like-NCBI HMM Modified: NF000501.2 blaOXA-229_like updated to NF000501.2 blaOXA-22_like-NCBI HMM Modified: NF000502.2 blaOXA-85_like updated to NF000502.2 blaOXA_Campylobacter-NCBI HMM Modified: NF000503.1 fusF updated to NF000503.1 fusid_est_FusH-NCBI HMM Modified: NF000504.1 stregram_VatH updated to NF000504.1 stregram_VatI-NCBI HMM Modified: NF000505.2 blaGIL updated to NF000505.2 blaGIM-NCBI HMM Modified: NF000506.1 tet_ABC_AB_A updated to NF000506.1 tet_ABC_AB_B-NCBI HMM Modified: NF000507.1 AAC_6p_Ie updated to NF000507.1 AAC_6p_Ie_fam-NCBI HMM Modified: NF000508.1 APH_2pp_Ia updated to NF000508.1 APH_2pp_Ie_IVa-NCBI HMM Modified: NF000509.1 efflux_CmlA updated to NF000509.1 efflux_Cmx-NCBI HMM Modified: NF000510.1 efflux_Cmx updated to NF000510.1 efflux_OM_AdeC-NCBI HMM Modified: NF000511.2 blaCME updated to NF000511.2 blaCMH-NCBI HMM Modified: NF000512.2 blaSGM updated to NF000512.2 blaSIM-NCBI HMM Modified: NF000513.2 blaFTU updated to NF000513.2 blaGES-NCBI HMM Modified: NF000514.1 ABCF_OptrA updated to NF000514.1 ABCF_Sal-NCBI HMM Modified: NF000516.1 EreD updated to NF000516.1 Erm23S_rRNA_broad-NCBI HMM Modified: NF000517.2 blaCBP updated to NF000517.2 blaCDD-NCBI HMM Modified: NF000518.2 blaVCC updated to NF000518.2 blaVEB-NCBI HMM Modified: NF000519.2 blaPDC_var updated to NF000519.2 blaPEDO-1_fam-NCBI HMM Modified: NF000520.2 blaOXA-286_like updated to NF000520.2 blaOXA-2_like-NCBI HMM Modified: NF000531.2 blaTEM updated to NF000531.2 blaTHIN-NCBI HMM Modified: NF000538.0 classA_carba updated to NF000538.0 classA_firm-NCBI HMM Modified: NF007456.1 PRK10026.1 updated to NF007456.1 PRK13747.1-PRKfam HMM Modified: NF010310.2 PRK13747.1 updated to NF010310.2 PRK13752.1-PRKfam HMM Modified: NF010315.0 PRK13752.1 updated to NF010315.0 PSE-NCBI HMM Modified: NF012098.1 blaBPU updated to NF012098.1 blaCAM-NCBI HMM Modified: NF012099.1 SubclassA2 updated to NF012099.1 Sul1-NCBI HMM Modified: NF012100.0 blaVIM updated to NF012100.0 blaZ-NCBI HMM Modified: NF012101.1 blaGOB updated to NF012101.1 blaIMI-NCBI HMM Modified: NF012102.1 blaDHA updated to NF012102.1 blaDIM-NCBI HMM Modified: NF012103.0 blaGES updated to NF012103.0 blaGIL-NCBI HMM Modified: NF012137.0 bla_xUS updated to NF012137.0 ble_BLMA_gen-NCBI HMM Modified: NF012140.0 blaBJP updated to NF012140.0 blaBKC-NCBI HMM Modified: NF012141.0 blaKPC updated to NF012141.0 blaL-NCBI HMM Modified: NF012142.0 blaSME updated to NF012142.0 blaSPG-1_fam-NCBI HMM Modified: NF012143.0 SHV_LEN_OKP updated to NF012143.0 SMB1_fam-NCBI HMM Modified: NF012145.1 blaDIM_SIM_IMP updated to NF012145.1 blaEBR-NCBI HMM Modified: NF012146.1 blaB-IND-MUS updated to NF012146.1 blaB-NCBI HMM Modified: NF012147.1 blaIMP updated to NF012147.1 blaIND-NCBI HMM Modified: NF012148.0 blaKHM-HMB updated to NF012148.0 blaKLUC-NCBI HMM Modified: NF012149.0 blaIND updated to NF012149.0 blaKHM-HMB-NCBI HMM Modified: NF012150.3 blaSPM updated to NF012150.3 blaSRT-NCBI HMM Modified: NF012151.0 penta_rpt_QnrAS updated to NF012151.0 penta_rpt_QnrB-NCBI HMM Modified: NF012152.0 penta_rpt_QnrC updated to NF012152.0 penta_rpt_QnrD-NCBI HMM Modified: NF012153.1 tet_protect updated to NF012153.1 tet_protect_M-NCBI HMM Modified: NF012154.0 tet_protect_Q updated to NF012154.0 tet_prtrans_34-NCBI HMM Modified: NF012155.1 tet_protect_M updated to NF012155.1 tet_protect_M_W-NCBI HMM Modified: NF012156.1 blaP updated to NF012156.1 blaPAC-NCBI HMM Modified: NF012157.0 ANT_3pp_I updated to NF012157.0 ANT_3pp_II-NCBI HMM Modified: NF012158.1 macrolide_MphE updated to NF012158.1 macrolide_MphF-NCBI HMM Modified: NF012159.0 polymyxin_MCR2 updated to NF012159.0 polymyxin_MCR3-NCBI HMM Modified: NF012160.0 APH_6_Steno updated to NF012160.0 APH_7pp_Ia-NCBI HMM Modified: NF012161.0 bla_class_D_main updated to NF012161.0 bla_subclass_B1-NCBI HMM Modified: NF012165.0 AAC_6p_set_A updated to NF012165.0 ABCF_CarA-NCBI HMM Modified: NF012167.0 classA_firm updated to NF012167.0 cmlA_floR-NCBI HMM Modified: NF012169.0 qepA updated to NF012169.0 rRNA_meth_EmtA-NCBI HMM Modified: NF012170.0 qac_SMR_J updated to NF012170.0 qepA-NCBI HMM Modified: NF012171.0 APH_6 updated to NF012171.0 APH_6_Ic-NCBI HMM Modified: NF012172.1 FOX-MOX updated to NF012172.1 FexA-NCBI HMM Modified: NF012173.1 CMY2-MIR-ACT-EC updated to NF012173.1 CMY2-NCBI HMM Modified: NF012174.0 tet_MFS_A_B_C_D updated to NF012174.0 tet_MFS_B-NCBI HMM Modified: NF012175.1 tet_MFS_L_K_45 updated to NF012175.1 tet_MFS_OtrB-NCBI HMM Modified: NF012176.0 tet_MFS_38 updated to NF012176.0 tet_MFS_40-NCBI HMM Modified: NF012177.1 tet_MFS_42 updated to NF012177.1 tet_MFS_43-NCBI HMM Modified: NF012178.0 tet_MFS_V updated to NF012178.0 tet_MFS_Y-NCBI HMM Modified: NF012180.1 tet_MFS_43 updated to NF012180.1 tet_MFS_45-NCBI HMM Modified: NF012183.0 tet_MFS_K updated to NF012183.0 tet_MFS_L-NCBI HMM Modified: NF012184.0 tet_MFS_45 updated to NF012184.0 tet_MFS_A-NCBI HMM Modified: NF012185.0 tet_MFS_L updated to NF012185.0 tet_MFS_L_K_45-NCBI HMM Modified: NF012186.0 tet_MFS_D updated to NF012186.0 tet_MFS_E-NCBI HMM Modified: NF012187.0 tet_MFS_E updated to NF012187.0 tet_MFS_G-NCBI HMM Modified: NF012188.1 tet_MFS_Y updated to NF012188.1 tet_NaH_anti_35-NCBI HMM Modified: NF012190.1 tet_MFS_B updated to NF012190.1 tet_MFS_C-NCBI HMM Modified: NF012191.0 tet_MFS_C updated to NF012191.0 tet_MFS_D-NCBI HMM Modified: NF012192.0 tet_MFS_G updated to NF012192.0 tet_MFS_H-NCBI HMM Modified: NF012193.0 tet_MFS_A updated to NF012193.0 tet_MFS_A_B_C_D-NCBI HMM Modified: NF012194.0 tet_MFS_J updated to NF012194.0 tet_MFS_K-NCBI HMM Modified: NF012195.0 tet_MFS_H updated to NF012195.0 tet_MFS_H_J-NCBI HMM Modified: NF012199.0 cml_V_MFS updated to NF012199.0 cmx_cmrA-NCBI HMM Modified: NF012202.0 ble_MBL updated to NF012202.0 ble_Sh-NCBI HMM Modified: NF012203.0 cmlB1_MFS updated to NF012203.0 cml_V_MFS-NCBI HMM Modified: NF012207.0 tet_MFS_H_J updated to NF012207.0 tet_MFS_J-NCBI HMM Modified: NF012212.0 ANT_9 updated to NF012212.0 APH_2pp_IIIa-NCBI HMM Modified: NF012213.0 VanC1_ser_lig updated to NF012213.0 VarG_fam_MBL-NCBI HMM Modified: NF012214.1 D_ala_D_ser_VanC updated to NF012214.1 D_ala_D_ser_VanE-NCBI HMM Modified: NF012215.1 D_ala_D_lac_VanD updated to NF012215.1 D_ala_D_lac_VanF-NCBI HMM Modified: NF012216.1 D_ala_D_lac_VanB updated to NF012216.1 D_ala_D_lac_VanD-NCBI HMM Modified: NF012217.1 D_ala_D_lac_VanA updated to NF012217.1 D_ala_D_lac_VanB-NCBI HMM Modified: NF012218.0 erm_38_23S_MT updated to NF012218.0 erm_A_23S_MT-NCBI HMM Modified: NF012219.1 erm_C_23S_MT updated to NF012219.1 erm_F_23S_MT-NCBI HMM Modified: NF012220.1 erm_B_23S_MT updated to NF012220.1 erm_C_23S_MT-NCBI HMM Modified: NF012222.1 erm_A_23S_MT updated to NF012222.1 erm_B_23S_MT-NCBI HMM Modified: NF012223.0 erm_F_23S_MT updated to NF012223.0 erm_SHROVE-NCBI HMM Modified: NF012224.1 blaSFH updated to NF012224.1 blaSFH_gen-NCBI HMM Modified: NF012225.0 blaSFH_gen updated to NF012225.0 blaSGM-NCBI HMM Modified: NF012229.1 bla_class_B_core updated to NF012229.1 bla_class_C-NCBI HMM Modified: NF028535.0 ANT_4p_II updated to NF028535.0 ANT_4p_Ia-NCBI HMM Modified: NF032892.0 fosA7 updated to NF032892.0 fosA8-NCBI HMM Modified: NF032894.1 APH_3pp_Ia updated to NF032894.1 APH_3pp_Ib-NCBI HMM Modified: NF032895.1 APH_3pp_Ib updated to NF032895.1 APH_4_Ia-NCBI HMM Modified: NF032896.1 APH_3pp updated to NF032896.1 APH_3pp_Ia-NCBI HMM Modified: NF032897.1 APH_3p_V updated to NF032897.1 APH_3p_VI-NCBI HMM Modified: NF032898.1 APH_3p_II updated to NF032898.1 APH_3p_IIIa-NCBI HMM Modified: NF033059.2 APH_3p_I updated to NF033059.2 APH_3p_II-NCBI HMM Modified: NF033060.0 blaBCL updated to NF033060.0 blaBEL-NCBI HMM Modified: NF033061.1 ANT_4p_I updated to NF033061.1 ANT_4p_II-NCBI HMM Modified: NF033062.0 APH_3p_VI updated to NF033062.0 APH_3p_VIII-NCBI HMM Modified: NF033063.0 APH_3p_XV updated to NF033063.0 APH_3pp-NCBI HMM Modified: NF033064.0 APH_3p_IIIa updated to NF033064.0 APH_3p_IVa-NCBI HMM Modified: NF033065.0 APH_3p_IVa updated to NF033065.0 APH_3p_V-NCBI HMM Modified: NF033066.0 APH_3p_VIII updated to NF033066.0 APH_3p_VIIa-NCBI HMM Modified: NF033067.1 APH_3p_VIIa updated to NF033067.1 APH_3p_XV-NCBI HMM Modified: NF033068.1 APH_3p updated to NF033068.1 APH_3p_A16-NCBI HMM Modified: NF033074.0 AAC_6p_Ib updated to NF033074.0 AAC_6p_Id-NCBI HMM Modified: NF033075.0 AAC_6p_Steno updated to NF033075.0 AAC_6p_Strep-NCBI HMM Modified: NF033076.0 AAC_6p_Yersi updated to NF033076.0 AAC_6p_set_A-NCBI HMM Modified: NF033077.0 AAC_6p_A30 updated to NF033077.0 AAC_6p_A31-NCBI HMM Modified: NF033078.2 AAC_6p_Ia_fam updated to NF033078.2 AAC_6p_Iad-NCBI HMM Modified: NF033080.0 AAC_3_II updated to NF033080.0 AAC_3_IV-NCBI HMM Modified: NF033081.0 AAC_3_IV updated to NF033081.0 AAC_3_VIII-NCBI HMM Modified: NF033082.0 AAC_3 updated to NF033082.0 AAC_3_I-NCBI HMM Modified: NF033083.0 AAC_3_I updated to NF033083.0 AAC_3_II-NCBI HMM Modified: NF033084.2 ANT_6 updated to NF033084.2 ANT_6_aadK-NCBI HMM Modified: NF033085.1 bla_class_C updated to NF033085.1 bla_class_D_alt-NCBI HMM Modified: NF033087.1 bla_subclass_B2 updated to NF033087.1 bla_subclass_B3-NCBI HMM Modified: NF033088.1 bla_subclass_B1 updated to NF033088.1 bla_subclass_B2-NCBI HMM Modified: NF033089.1 blaCTX-M updated to NF033089.1 blaCcrA-NCBI HMM Modified: NF033090.1 HK_VanS_B updated to NF033090.1 HK_VanS_O-NCBI HMM Modified: NF033091.0 HK_VanS_ACDEFG updated to NF033091.0 HK_VanS_B-NCBI HMM Modified: NF033094.0 HK_VanS_O updated to NF033094.0 L2-NCBI HMM Modified: NF033095.1 bla_Bc_2 updated to NF033095.1 bla_CblA-NCBI HMM Modified: NF033096.1 bla1 updated to NF033096.1 blaACC-NCBI HMM Modified: NF033098.1 bla_CblA updated to NF033098.1 bla_CepA-NCBI HMM Modified: NF033099.1 bla_Exo updated to NF033099.1 bla_class_A-NCBI HMM Modified: NF033100.1 bla_CfxA updated to NF033100.1 bla_Exo-NCBI HMM Modified: NF033101.0 blaL updated to NF033101.0 blaL1-NCBI HMM Modified: NF033102.1 bla_CepA updated to NF033102.1 bla_CfxA-NCBI HMM Modified: NF033103.1 bla_class_A updated to NF033103.1 bla_class_B_core-NCBI HMM Modified: NF033104.0 blaOXA-46_like updated to NF033104.0 blaOXA-48_like-NCBI HMM Modified: NF033105.1 bla_subclass_B3 updated to NF033105.1 bla_xUS-NCBI HMM Modified: NF033106.1 blaL1 updated to NF033106.1 blaLAP-NCBI HMM Modified: NF033107.1 blaB updated to NF033107.1 blaBBI-NCBI HMM Modified: NF033108.1 sensor_BlaR1 updated to NF033108.1 sensor_MecR1-NCBI HMM Modified: NF033109.1 sensor_MecR1 updated to NF033109.1 stat-NCBI HMM Modified: NF033111.2 tet_monoox_X updated to NF033111.2 tet_protect-NCBI HMM Modified: NF033112.0 APH_3p_A16 updated to NF033112.0 APH_3p_I-NCBI HMM Modified: NF033114.1 phos_trans_CPT updated to NF033114.1 poly_MCR3_broad-NCBI HMM Modified: NF033115.1 dipept_VanX updated to NF033115.1 efflux_CmlA-NCBI HMM Modified: NF033117.2 vanR_ACDEGLN updated to NF033117.2 vanR_FM-NCBI HMM Modified: NF033118.1 vanR-O updated to NF033118.1 vanR_ACDEGLN-NCBI HMM Modified: NF033120.0 vanR_FM updated to NF033120.0 vanT-CELN-NCBI HMM Modified: NF033122.1 vanW-B updated to NF033122.1 vanW-G-NCBI HMM Modified: NF033123.1 vanW-G updated to NF033123.1 vanW-gen-NCBI HMM Modified: NF033125.2 vanZ-A updated to NF033125.2 vanZ-F-NCBI HMM Modified: NF033126.1 ANT_3pp_AadA1 updated to NF033126.1 ANT_3pp_AadA3-NCBI HMM Modified: NF033127.1 ANT_3pp_AadA3 updated to NF033127.1 ANT_3pp_I-NCBI HMM Modified: NF033128.2 vanW-gen updated to NF033128.2 vanXY-NCBI HMM Modified: NF033129.1 macro_glyco_Mgt updated to NF033129.1 macrolide_MefA-NCBI HMM Modified: NF033130.1 AAC_6p_A48 updated to NF033130.1 AAC_6p_A49-NCBI HMM Modified: NF033131.1 vanT-G-Cterm updated to NF033131.1 vanT-L-cat-NCBI HMM Modified: NF033132.1 vanT-CELN updated to NF033132.1 vanT-G-Cterm-NCBI HMM Modified: NF033133.1 vanT-L-cat updated to NF033133.1 vanT-L-mem-NCBI HMM Modified: NF033135.1 cmx_cmrA updated to NF033135.1 coreg_MerD-NCBI HMM Modified: NF033136.1 SMR_qac_K updated to NF033136.1 SMR_qac_bcrB-NCBI HMM Modified: NF033137.0 SMR_qac_int updated to NF033137.0 SMR_qac_pB8-NCBI HMM Modified: NF033139.1 blaZ updated to NF033139.1 blaZ_gen-NCBI HMM Modified: NF033140.0 blaZ_mecC_type updated to NF033140.0 bla_B2_CphA-NCBI HMM Modified: NF033141.0 blaZ_gen updated to NF033141.0 blaZ_mecC_type-NCBI HMM Modified: NF033142.1 efflux_OM_AdeC updated to NF033142.1 emrE-Resfams HMM Modified: NF033144.1 rifampin_ARR updated to NF033144.1 rifampin_ARR_Ms-NCBI HMM Modified: NF033145.1 rif_monoox updated to NF033145.1 rifampin_ARR-NCBI HMM Modified: NF033148.1 tet_protect_M_W updated to NF033148.1 tet_protect_Q-NCBI HMM Modified: NF033149.0 CHL_hydrolase updated to NF033149.0 CMY2-MIR-ACT-EC-NCBI HMM Modified: NF033150.1 AAC_6p_A49 updated to NF033150.1 AAC_6p_Acine-NCBI HMM Modified: NF033151.0 AAC_6p_A10 updated to NF033151.0 AAC_6p_A29-NCBI HMM Modified: NF033152.0 BlaA_Yent updated to NF033152.0 BlaEC-NCBI HMM Modified: NF033156.1 ble_BLMA_gen updated to NF033156.1 ble_BLMT-NCBI HMM Modified: NF033159.0 blaPAC updated to NF033159.0 blaPAU-NCBI HMM Modified: NF033174.0 blaPSV updated to NF033174.0 blaR1_generic-NCBI HMM Modified: NF033180.1 AAC_3_VIII updated to NF033180.1 AAC_3_VIa-NCBI HMM Modified: NF033182.0 linco_LnuG updated to NF033182.0 linco_LnuP-NCBI HMM Modified: NF033204.1 blaRUB updated to NF033204.1 blaSCO-NCBI HMM Modified: NF033209.1 16S_rRNA_Rmt_B updated to NF033209.1 16S_rRNA_Rmt_C-NCBI HMM Modified: NF033211.1 blaCRH updated to NF033211.1 blaCSA-NCBI HMM Modified: NF033220.1 ANT_3pp_II updated to NF033220.1 ANT_4p_I-NCBI HMM Modified: NF033221.1 aadE-Cc updated to NF033221.1 acid_shock_Asr-NCBI HMM Modified: NF033374.6 AAC_6p_Id updated to NF033374.6 AAC_6p_Ie-NCBI HMM Modified: NF033375.2 penta_rpt_QnrE updated to NF033375.2 penta_rpt_QnrS-NCBI HMM Modified: NF033378.1 MECD_PBP updated to NF033378.1 MFS_efflux_PexA-NCBI HMM Modified: NF033386.1 blaARL updated to NF033386.1 blaAXC-NCBI HMM Modified: NF033387.1 ANT_6_aadS updated to NF033387.1 ANT_6_str-NCBI HMM Modified: NF033398.1 rRNA_meth_EmtA updated to NF033398.1 ribo_prot_ABC_F-NCBI HMM Modified: NF033405.1 FosL updated to NF033405.1 FosX-NCBI HMM Modified: NF033406.1 blaMCA updated to NF033406.1 blaMSI-1_fam-NCBI HMM Modified: NF033408.5 polymyxin_MCR3 updated to NF033408.5 polymyxin_MCR4-NCBI HMM Modified: NF033409.0 poly_MCR3_broad updated to NF033409.0 polymyxin_MCR1-NCBI HMM Modified: NF033462.1 polymyxin_MCR4 updated to NF033462.1 polymyxin_MCR5-NCBI HMM Modified: NF033463.1 polymyxin_MCR5 updated to NF033463.1 polymyxin_MCR6-NCBI HMM Modified: NF033466.0 blaRCP updated to NF033466.0 blaRHO-NCBI HMM Modified: NF033467.0 blaAQU updated to NF033467.0 blaARL-NCBI HMM Modified: NF033468.1 stregram_VatI updated to NF033468.1 tet_ABC_46_A-NCBI HMM Modified: NF033469.1 SMR_qac_bcrB updated to NF033469.1 SMR_qac_bcrC-NCBI HMM Modified: NF033470.1 SMR_qac_bcrC updated to NF033470.1 SMR_qac_int-NCBI HMM Modified: NF033472.1 AAC_2p_IIb updated to NF033472.1 AAC_2p_Ia-NCBI HMM Modified: NF033473.1 trim_DfrE updated to NF033473.1 trim_DfrF-NCBI HMM Modified: NF033476.1 tet_destruct updated to NF033476.1 tet_monoox_X-NCBI HMM Modified: NF033502.0 Sul4 updated to NF033502.0 TlmB-NCBI HMM Modified: NF033509.1 blaOXA-22_like updated to NF033509.1 blaOXA-23_like-NCBI HMM Modified: NF033555.1 lyase_MerB updated to NF033555.1 macro_glyco_Mgt-NCBI HMM Modified: NF033560.1 merT_RC607 updated to NF033560.1 myrA-NCBI HMM Modified: NF033565.0 trans_MerF updated to NF033565.0 trans_reg_VanU-NCBI HMM Modified: NF033568.1 blaROB updated to NF033568.1 blaRUB-NCBI HMM Modified: NF033569.1 blaLHK updated to NF033569.1 blaLUT-NCBI HMM Modified: NF033574.1 VarG_fam_MBL updated to NF033574.1 Vat_ABCDEFH-NCBI HMM Modified: NF033575.1 blaRHO updated to NF033575.1 blaROB-NCBI HMM Modified: NF033582.2 blaALI updated to NF033582.2 blaAQU-NCBI HMM Modified: NF033584.1 blaPST updated to NF033584.1 blaPSV-NCBI HMM Modified: NF033585.1 blaTTU updated to NF033585.1 blaTUS-NCBI HMM Modified: NF033612.0 AAC_3_VIa updated to NF033612.0 AAC_3_XI-NCBI HMM Modified: NF033613.1 blaOXA-576_like updated to NF033613.1 blaOXA-58_like-NCBI HMM Modified: NF033614.1 APH_6_Ic_gen updated to NF033614.1 APH_6_Steno-NCBI HMM Modified: NF033626.1 blaBKC_GPC updated to NF033626.1 blaBPU-NCBI HMM Modified: NF033627.3 intimin_all updated to NF033627.3 intimin_alpha-NCBI HMM Modified: NF033636.1 acid_shock_Asr updated to NF033636.1 adeC-adeK-oprM-Resfams HMM Modified: NF033637.1 transloc_TIR updated to NF033637.1 transport_merC-NCBI HMM Modified: NF033639.1 intimin_alpha updated to NF033639.1 linco_LnuA-NCBI HMM Modified: NF033646.1 toxin_EAST1 updated to NF033646.1 trans_MerF-NCBI HMM Modified: NF033648.1 blaOXA-274_like updated to NF033648.1 blaOXA-286_like-NCBI HMM Modified: NF033658.1 Shiga_Stx1A updated to NF033658.1 Shiga_Stx1B-NCBI HMM Modified: NF033659.0 Shiga_Stx1B updated to NF033659.0 Shiga_Stx2A-NCBI HMM Modified: NF033660.0 Shiga_Stx2B updated to NF033660.0 SubclassA2-NCBI HMM Modified: NF033661.1 Shiga_Stx2A updated to NF033661.1 Shiga_Stx2B-NCBI HMM Modified: NF033666.1 blaOXA-727_like updated to NF033666.1 blaOXA-85_like-NCBI HMM Modified: NF033667.1 blaOXA-55_like updated to NF033667.1 blaOXA-576_like-NCBI HMM Modified: NF033669.1 polymyxin_MCR8 updated to NF033669.1 polymyxin_MCR9-NCBI HMM Modified: NF033670.1 polymyxin_MCR6 updated to NF033670.1 polymyxin_MCR7-NCBI HMM Modified: NF033671.1 polymyxin_MCR7 updated to NF033671.1 polymyxin_MCR8-NCBI HMM Modified: NF033692.1 APH_2pp_I_a_f_h updated to NF033692.1 APH_2pp_Ia-NCBI HMM Modified: NF033693.0 AAC_6p_Ie_fam updated to NF033693.0 AAC_6p_If-NCBI HMM Modified: NF033698.1 blaCSA updated to NF033698.1 blaCTX-M-NCBI HMM Modified: NF033700.1 blaCMA updated to NF033700.1 blaCME-NCBI HMM Modified: NF033702.0 blaOXA-12_like updated to NF033702.0 blaOXA-134_like-NCBI HMM Modified: NF033714.1 blaBBI updated to NF033714.1 blaBCL-NCBI HMM Modified: NF033727.1 chaperon_ArsD updated to NF033727.1 chloram_CatA-NCBI HMM Modified: NF033736.1 blaAFM updated to NF033736.1 blaAIM-NCBI HMM Modified: NF033781.1 chaper_CopP updated to NF033781.1 chaperon_ArsD-NCBI HMM Modified: NF033783.1 coreg_MerD updated to NF033783.1 cyto_nec_fctrs-NCBI HMM Modified: NF033784.1 transport_merC updated to NF033784.1 trim_DfrA10-NCBI HMM Modified: NF033786.1 phenyl_MerG updated to NF033786.1 phos_trans_CPT-NCBI HMM Modified: NF033815.0 blaOXA-364_like updated to NF033815.0 blaOXA-372_like-NCBI HMM Modified: NF033818.0 blaOXA-114_like updated to NF033818.0 blaOXA-12_like-NCBI HMM Modified: NF033834.1 RND_adapt_MexA updated to NF033834.1 RND_perm_OqxB-NCBI HMM Modified: NF033836.1 polymyxin_MCR9 updated to NF033836.1 qac_MFS_AB-NCBI HMM Modified: NF033851.1 trim_DfrA35 updated to NF033851.1 trim_DfrA36-NCBI HMM Modified: NF033866.1 blaCDD updated to NF033866.1 blaCIA-NCBI HMM Modified: NF033867.1 blaPAU updated to NF033867.1 blaPDC-NCBI HMM Modified: NF033868.0 trim_DfrA36 updated to NF033868.0 trim_DfrA3b-NCBI HMM Modified: NF033877.0 arsB_Sta_pI258 updated to NF033877.0 betalact_A_Burk_PenA-NCBI HMM Modified: NF033895.1 blaCAM updated to NF033895.1 blaCAU-NCBI HMM Modified: NF033929.1 blaAXC updated to NF033929.1 blaB-IND-MUS-NCBI HMM Modified: NF033933.0 fosA8 updated to NF033933.0 fusB-NCBI HMM Modified: TIGR02052.1 TIGR02052 updated to TIGR02052.1 MexE-Resfams HMM Modified: TIGR02053.1 TIGR02053 updated to TIGR02053.1 MerP-TIGRFAMs - Protein family changes: Total: Added 28 Total: Prev. Release 1499 Total: Removed 0 Total: This Release 1527 Family Added: hmm_id #fam_id Family Added: - afaC Family Added: - bin_CdtA Family Added: - bin_CdtB Family Added: - bmaE Family Added: - cvaC Family Added: - emrD Family Added: - focG Family Added: - ibeA Family Added: - iutA Family Added: - mcr-10 Family Added: - papA Family Added: - papC Family Added: - papE Family Added: - papG Family Added: - papG-I Family Added: - papG-II Family Added: - papG-III Family Added: - papH Family Added: - sfaF Family Added: - tcdA Family Added: - tcdB Family Added: - tcdC Family Added: - tcdE Family Added: - tcdR Family Added: - tcd_gen Family Added: - tva(A) Family Added: - tva(B) Family Changed: - blaOXA-266_fam updated to NF033653.1 blaOXA-266_fam --------------------------------------------------------------------- Changes included in 2019-09-06.1 --------------------------------------------------------------------- This release just removes two accidentally included "plus" proteins. We suggest you switch to AMRFinderPlus. See https://github.com/ncbi/amr/wiki for information an how to install since we will be dropping support for this version of AMRFinder soon. - Protein changes: Total: Added 0 Total: Prev. Release 5984 Total: Removed 2 Total: This Release 5982 Protein Removed: AAB91079.1 bind_CopB copper-binding_protein_CopB Protein Removed: BAB62907.1 cofA type_IV_pilus_CFA/III_major_pilin --------------------------------------------------------------------- Changes included in 2019-09-6.1 --------------------------------------------------------------------- This release removes three erroniously included proteins that were provided by collaborators, but accidentally released before review by curators. these sequences do not match the family, gene symbol, or protein name of the virulence and stress response families to which they had been added. There are no other changes. We will add controls to the database publication system to programmatically require that curators have manually reviewed all protein sequences before they become public. - Reference Gene Catalog protein and allele changes: Total in prev: 6274 Total in release: 6271 Removed: 3 Added: 0 Changed: 0 Removed copB AAB91079.1 Removed aaiC AHW84565.1 Removed cofA BAB62907.1 --------------------------------------------------------------------- Changes included in 2019-08-27.1 --------------------------------------------------------------------- This release includes a new database file to correspond with AMRFinderPlus version 3.1 that includes information for blacklisting of a few "plus" proteins common in some organisms that are interesting when found in others. This release also includes the usual new AMR genes and alleles; the fixing of some typos; removal of a redundant point mutation reference sequence; and the addition, reoorganization, and renaming of some "plus" genes. - Reference Gene Catalog protein and allele changes: Total in prev: 6110 Total in release: 6274 Removed: 18 Added: 182 Changed: 33 Removed emrD3 WP_000850833.1 Removed blaOXA-671 WP_016660101.1 Removed arsB-mob WP_063116263.1 Removed gyrA_A67S WP_001281242.1 Removed gyrA_A84P WP_001281242.1 Removed gyrA_D87G WP_001281242.1 Removed gyrA_D87H WP_001281242.1 Removed gyrA_D87N WP_001281242.1 Removed gyrA_D87V WP_001281242.1 Removed gyrA_D87Y WP_001281242.1 Removed gyrA_G81C WP_001281242.1 Removed gyrA_H80P WP_001281242.1 Removed gyrA_N57K WP_001281242.1 Removed gyrA_Q106H WP_001281242.1 Removed gyrA_S83F WP_001281242.1 Removed gyrA_S83I WP_001281242.1 Removed gyrA_S83L WP_001281242.1 Removed gyrA_S83W WP_001281242.1 Added arsB AAA21095.1 Added arsC AAA21096.1 Added arsR AAA25636.1 Added arsB AAA25637.1 Added copC AAA25808.1 Added arsR AAA27587.1 Added arsB AAA27588.1 Added arsR AAB09624.1 Added arsC AAB09628.1 Added arsC AAB42203.1 Added arsB AAB42204.1 Added ipaH9.8 AAC23714.1 Added pic AAD23953.1 Added efa1 AAD49229.2 Added iha AAG55323.1 Added stb AAK29747.1 Added efa1 AAL57562.1 Added pic AAN78833.1 Added iha AAN82058.1 Added cif AAQ07241.1 Added iha AAT68782.1 Added efa1 AAV91321.1 Added sab AAZ76500.1 Added senB AAZ89288.1 Added iha ABB17254.1 Added emrD3 ABQ18953.1 Added kdeA ABR76310.1 Added lmrC ABX00624.1 Added iha ACB20136.1 Added iha ACD08748.1 Added amvA ACQ82816.1 Added ipaH4 ADA74402.1 Added iha ADI47068.1 Added iha ADN47767.1 Added arsR ADZ44504.1 Added iha AEQ14190.1 Added stb AET14866.1 Added arsR AET17094.1 Added pic AFS72825.1 Added iha AFS75030.1 Added asr BAA15331.2 Added arsB BAA24823.1 Added arsC BAA24824.1 Added espK BAB34991.1 Added fieF BAB89353.1 Added fieF BAE77395.1 Added arsR BAE77793.1 Added cif BAG66370.1 Added iha BAI27255.1 Added efa1 BAI32294.1 Added iha CAC39288.1 Added efa1 CAC81883.1 Added efa1 CAD30848.1 Added stb CAD87835.1 Added iha CAE55782.1 Added efa1 CAI43818.1 Added hlyA-alpha CAQ77251.1 Added iha CAR09712.2 Added pic CAU99295.1 Added iha CBW53086.1 Added ipaH5 EID63069.1 Added fosB WP_000920239.1 Added dfrA36 WP_000949574.1 Added mphM WP_001041372.1 Added cfr(B) WP_002405682.1 Added mphK WP_003246254.1 Added blaPDC-374 WP_003454242.1 Added tet(56) WP_003635403.1 Added blaCDD-1 WP_009901927.1 Added mphH WP_015776248.1 Added erm(49) WP_019728092.1 Added blaCDD-2 WP_021361759.1 Added mphN WP_024127776.1 Added tet(X) WP_024160783.1 Added blaPDC-361 WP_031638595.1 Added tet(G) WP_032489471.1 Added vga(E) WP_032495718.1 Added blaACT-72 WP_045895620.1 Added blaACT-70 WP_047364854.1 Added blaACT-69 WP_048209719.1 Added ble WP_063842967.1 Added blaOXA-671 WP_081401608.1 Added icr-Mo WP_082741435.1 Added blaOXA-653 WP_087554513.1 Added tet(X) WP_094309310.1 Added blaMOX-13 WP_096807444.1 Added blaFOX-15 WP_096807445.1 Added blaCMY-157 WP_096807446.1 Added blaIMP-69 WP_099156051.1 Added blaPDC-249 WP_104009845.1 Added blaACT-58 WP_111965422.1 Added blaACT-62 WP_111967096.1 Added blaACT-63 WP_112780466.1 Added blaOXA-727 WP_114272532.1 Added blaOXA-731 WP_116786833.1 Added blaOXA-728 WP_116786835.1 Added blaPDC-367 WP_121286063.1 Added blaPDC-364 WP_121347819.1 Added blaFLC-1 WP_123061077.1 Added blaPDC-371 WP_126118969.1 Added blaPDC-353 WP_128550481.1 Added blaVIM-67 WP_142875125.1 Added blaADC-196 WP_145850033.1 Added blaAQU WP_148044401.1 Added blaAQU WP_148044402.1 Added dfrA29 WP_148044403.1 Added blaCAM-1 WP_148044405.1 Added blaCMY-165 WP_148044406.1 Added blaCMY-166 WP_148044407.1 Added blaCMY-167 WP_148044408.1 Added blaCTX-M-227 WP_148044409.1 Added blaCTX-M-228 WP_148044410.1 Added blaCTX-M-229 WP_148044411.1 Added blaDHA-29 WP_148044412.1 Added blaGES-42 WP_148044413.1 Added blaGES-43 WP_148044414.1 Added blaIMP-82 WP_148044416.1 Added blaIMP-83 WP_148044417.1 Added blaIMP-84 WP_148044418.1 Added blaKPC-41 WP_148044419.1 Added blaKPC-45 WP_148044420.1 Added blaKPC-46 WP_148044421.1 Added blaOXA-835 WP_148044422.1 Added blaOXA-836 WP_148044423.1 Added blaPAU-1 WP_148044424.1 Added blaPDC-196 WP_148044425.1 Added blaPDC-334 WP_148044426.1 Added blaPDC-335 WP_148044427.1 Added blaPDC-336 WP_148044428.1 Added blaPDC-337 WP_148044429.1 Added blaPDC-338 WP_148044430.1 Added blaPDC-339 WP_148044431.1 Added blaPDC-340 WP_148044432.1 Added blaPDC-341 WP_148044433.1 Added blaPDC-342 WP_148044434.1 Added blaPDC-343 WP_148044435.1 Added blaPDC-344 WP_148044436.1 Added blaPDC-345 WP_148044437.1 Added blaPDC-346 WP_148044438.1 Added blaPDC-347 WP_148044439.1 Added blaPDC-348 WP_148044440.1 Added blaPDC-349 WP_148044441.1 Added blaPDC-350 WP_148044442.1 Added blaPDC-351 WP_148044443.1 Added blaPDC-352 WP_148044444.1 Added blaPDC-354 WP_148044445.1 Added blaPDC-355 WP_148044446.1 Added blaPDC-356 WP_148044447.1 Added blaPDC-357 WP_148044448.1 Added blaPDC-358 WP_148044449.1 Added blaPDC-359 WP_148044450.1 Added blaPDC-360 WP_148044451.1 Added blaPDC-362 WP_148044452.1 Added blaPDC-363 WP_148044453.1 Added blaPDC-365 WP_148044454.1 Added blaPDC-366 WP_148044455.1 Added blaPDC-368 WP_148044456.1 Added blaPDC-369 WP_148044457.1 Added blaPDC-370 WP_148044458.1 Added blaPDC-372 WP_148044459.1 Added blaPDC-373 WP_148044460.1 Added blaPDC-375 WP_148044461.1 Added blaPDC-376 WP_148044462.1 Added blaPDC-377 WP_148044463.1 Added blaPDC-378 WP_148044464.1 Added blaPDC-379 WP_148044465.1 Added blaPDC-380 WP_148044466.1 Added blaPDC-381 WP_148044467.1 Added blaPDC-382 WP_148044468.1 Added blaPDC-383 WP_148044469.1 Added blaPFM-1 WP_148044470.1 Added blaTEM-241 WP_148044472.1 Added blaTEM-242 WP_148044473.1 Added blaTEM-39 WP_148044474.1 Added blaVEB-22 WP_148044475.1 Added blaVIM-68 WP_148044476.1 Added mcr-1.22 WP_148044477.1 Added mcr-5.4 WP_148044478.1 Added blaOXA-837 WP_148281568.1 Added gyrA_H80P WP_001281243.1 Added gyrA_N57K WP_001281243.1 Added gyrA_S83F WP_001281243.1 Changes: faeG AAA24032.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG faeG AAA24035.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG faeG AAA24390.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG nccX AAA65102.1 subclass METAL -> merB AAA88369.1 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY merC AAC33908.1 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY faeG AAC34727.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG merB AAC38230.1 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY merC AAC38233.1 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY ipaH2 AAN43435.1 gene_family ipaH9.8 -> ipaH2 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 mreA AAN68577.1 subclass METAL -> ipaH2 AAZ87985.1 gene_family ipaH9.8 -> ipaH2 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 ipaH3 ABB62096.1 gene_family ipaH9.8 -> ipaH3 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH3 ipaH2 ABB62098.1 gene_family ipaH9.8 -> ipaH2 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 ipaH2 ABB66229.1 gene_family ipaH9.8 -> ipaH2 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 ipaH1 ABF02983.1 gene_family ipaH9.8 -> ipaH1 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH1/H6 ipaH2 ABF04028.1 gene_family ipaH9.8 -> ipaH2 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 faeG ACB72721.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG ipaH2 ACD09076.1 gene_family ipaH9.8 -> ipaH2 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 faeG AFH14350.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG merC BAA14138.2 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY merB BAA20338.2 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY merG BAA23166.1 class MECURY -> MERCURY merB BAB47641.1 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY merB CAC86907.1 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY faeG CAE82650.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG faeG CAE82653.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG faeG CAE82670.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG mphL WP_002047670.1 gene_family mph(B) -> mphL product_name Mph(B) family macrolide 2'-phosphotransferase -> macrolide 2'-phosphotransferase MphL poxtA WP_002415638.1 genbank_cds_start 1856 -> 57639 genbank_cds_stop 3484 -> 59267 genbank_nucleotide_accession MF095097.1 -> MH746818.1 mcr-3.22 WP_094308975.1 refseq_nucleotide_accession NG_060581.1 -> NG_060581.2 blaPDC-259 WP_109791193.1 genbank_nucleotide_accession MH243333.1 -> MH243333.2 refseq_nucleotide_accession NG_057591.1 -> NG_057591.2 blaPDC-265 WP_109791199.1 genbank_nucleotide_accession MH243339.1 -> MH243339.2 refseq_nucleotide_accession NG_057597.1 -> NG_057597.2 - HMM library Changes: Total: Added 6 Total: Prev. Release 603 Total: Removed 1 Total: This Release 608 HMM Removed: NF000274.2 PF04439 HMM Added: NF007456.1 PRK10026.1 HMM Added: NF033636.1 acid_shock_Asr HMM Added: NF033877.0 arsB_Sta_pI258 HMM Added: NF033895.1 blaCAM HMM Added: NF033929.1 blaAXC HMM Added: NF033933.0 fosA8 - Protein family changes: Total: Added 47 Total: Prev. Release 1454 Total: Removed 1 Total: This Release 1500 Family Removed: - ubiq_IpaH3 Family Added: - ACID Family Added: - CDF_efflux Family Added: - amvA Family Added: NF033877.0 arsB_pI258 Family Added: - arsB_pKW301 Family Added: - arsB_pYV Family Added: NF007456.1 arsC_gluta Family Added: - arsR Family Added: - arsR_K-12 Family Added: - arsR_R46 Family Added: - arsR_pI258 Family Added: - arsR_pKW301 Family Added: - arsR_pSX267 Family Added: - arsR_pYV Family Added: NF033636.1 asr Family Added: NF033929.1 blaAXC Family Added: NF033895.1 blaCAM Family Added: - blaPFM Family Added: - cif Family Added: - copC_Psyr Family Added: - dfrA29 Family Added: - efa1 Family Added: - erm(49) Family Added: - espK Family Added: - fieF Family Added: NF033933.0 fosA8 Family Added: - hlyA-alpha Family Added: - icr-Mo Family Added: - iha Family Added: - ipaH1 Family Added: - ipaH2 Family Added: - ipaH3 Family Added: - ipaH4 Family Added: - ipaH5 Family Added: - ipa_gen Family Added: - kdeA Family Added: - lmrC_abcf Family Added: - mphH Family Added: - mphK Family Added: - mphL Family Added: - mphM Family Added: - mphN Family Added: - pic_auto Family Added: - sab Family Added: - senB Family Added: - stb Family Added: - tet(56) Family Changed: NF000274.2 ant6_gen updated to - ant6_gen --------------------------------------------------------------------- Changes included in 2019-07-10.1 --------------------------------------------------------------------- New alleles and sequences were added, a few product names were made more specific as more phenotype information became available. Cleanup of the database caused some families and HMMs not used by AMRFinderPlus to be removed. - Protein changes: Total: Added 57 Total: Prev. Release 5757 Total: Removed 3 Total: This Release 5811 Protein Removed: WP_029728367.1 blaB BlaB_family_subclass_B1_metallo-beta-lactamase Protein Removed: WP_063842622.1 blaB BlaB_family_subclass_B1_metallo-beta-lactamase Protein Removed: WP_063842629.1 blaGOB GOB_family_subclass_B3_metallo-beta-lactamase Protein Added: AAA21095.1 arsB_R773 arsenite_efflux_transporter_membrane_subunit_ArsB Protein Added: ABQ18953.1 emrD3 multidrug_efflux_MFS_transporter_EmrD-3 Protein Added: WP_000850833.1 emrD3 multidrug_efflux_MFS_transporter_EmrD-3 Protein Added: WP_010446567.1 tet(B) tetracycline_efflux_MFS_transporter_Tet(B) Protein Added: WP_039902635.1 blaOXA-134_like OXA-134_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-646 Protein Added: WP_063116263.1 arsB_R773 arsenite_efflux_transporter_membrane_subunit_ArsB Protein Added: WP_063844329.1 dfrA12 trimethoprim-resistant_dihydrofolate_reductase_DfrA12 Protein Added: WP_063856066.1 tet(B) tetracycline_efflux_MFS_transporter_Tet(B) Protein Added: WP_063856068.1 tet(B) tetracycline_efflux_MFS_transporter_Tet(B) Protein Added: WP_070342370.1 dfrA7 trimethoprim-resistant_dihydrofolate_reductase_DfrA7 Protein Added: WP_071593205.1 aadA1bt ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA1bt Protein Added: WP_071593208.1 aadA1bt ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA1bt Protein Added: WP_086264536.1 blaOXA-213_like OXA-213_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-832 Protein Added: WP_094323230.1 mcr-2 phosphoethanolamine--lipid_A_transferase_MCR-2.3 Protein Added: WP_110174956.1 blaTEM class_A_beta-lactamase_TEM-235 Protein Added: WP_125052736.1 blaOXA-51_like OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-834 Protein Added: WP_129336087.1 mcr-1 phosphoethanolamine--lipid_A_transferase_MCR-1.19 Protein Added: WP_135350920.1 blaGES class_A_beta-lactamase_GES-41 Protein Added: WP_140423191.1 aac(6')-Ib AAC(6')-Ib_family_aminoglycoside_6'-N-acetyltransferase Protein Added: WP_140423278.1 aadA1 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA1 Protein Added: WP_140423279.1 aadA2 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA2 Protein Added: WP_140423280.1 aadA2 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA2 Protein Added: WP_140423281.1 aadA2 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA2 Protein Added: WP_140423282.1 aadA5 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA5 Protein Added: WP_140423283.1 dfrA1 trimethoprim-resistant_dihydrofolate_reductase_DfrA1 Protein Added: WP_140423284.1 dfrA12 trimethoprim-resistant_dihydrofolate_reductase_DfrA12 Protein Added: WP_140423285.1 dfrA17 trimethoprim-resistant_dihydrofolate_reductase_DfrA17 Protein Added: WP_140423286.1 dfrA17 trimethoprim-resistant_dihydrofolate_reductase_DfrA17 Protein Added: WP_140423287.1 dfrA17 trimethoprim-resistant_dihydrofolate_reductase_DfrA17 Protein Added: WP_140423305.1 blaADC class_C_beta-lactamase_ADC-195 Protein Added: WP_140423306.1 blaB subclass_B1_metallo-beta-lactamase_BlaB-15 Protein Added: WP_140423307.1 blaCMY class_C_beta-lactamase_CMY-164 Protein Added: WP_140423308.1 blaFRI carbapenem-hydrolyzing_class_A_beta-lactamase_FRI-8 Protein Added: WP_140423309.1 blaFRI carbapenem-hydrolyzing_class_A_beta-lactamase_FRI-9 Protein Added: WP_140423310.1 blaIMI carbapenem-hydrolyzing_class_A_beta-lactamase_IMI-19 Protein Added: WP_140423311.1 blaKPC carbapenem-hydrolyzing_class_A_beta-lactamase_KPC-44 Protein Added: WP_140423312.1 blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-643 Protein Added: WP_140423313.1 blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-644 Protein Added: WP_140423314.1 blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-645 Protein Added: WP_140423315.1 blaOXA-134_like OXA-134_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-647 Protein Added: WP_140423316.1 blaOXA-134_like OXA-134_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-648 Protein Added: WP_140423317.1 blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-650 Protein Added: WP_140423318.1 blaOXA-143_like OXA-143_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-825 Protein Added: WP_140423319.1 blaOXA-213_like OXA-213_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-826 Protein Added: WP_140423320.1 blaOXA-10_like OXA-10_family_class_D_beta-lactamase_OXA-827 Protein Added: WP_140423321.1 blaOXA-51_like OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-828 Protein Added: WP_140423322.1 blaOXA-51_like OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-829 Protein Added: WP_140423323.1 blaOXA-51_like OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-831 Protein Added: WP_140423324.1 blaOXA-48_like OXA-48_family_class_D_beta-lactamase_OXA-833 Protein Added: WP_140423325.1 blaPDC class_C_beta-lactamase_PDC-333 Protein Added: WP_140423326.1 blaPOM subclass_B3_metallo-beta-lactamase_POM-2 Protein Added: WP_140423327.1 blaVIM subclass_B1_metallo-beta-lactamase_VIM-64 Protein Added: WP_140423328.1 blaVIM subclass_B1_metallo-beta-lactamase_VIM-65 Protein Added: WP_140423329.1 mcr-1 phosphoethanolamine--lipid_A_transferase_MCR-1.20 Protein Added: WP_140423330.1 mcr-1 phosphoethanolamine--lipid_A_transferase_MCR-1.21 Protein Added: WP_140423331.1 mcr-3 phosphoethanolamine--lipid_A_transferase_MCR-3.26 Protein Added: WP_140423332.1 mcr-3 phosphoethanolamine--lipid_A_transferase_MCR-3.30 Protein Modified: ACM67153.1 lamda-2 intimin_type_lambda updated to ACM67153.1 lambda-2 intimin_type_lambda Protein Modified: WP_001100753.1 blaPER class_A_extended-spectrum_beta-lactamase_PER-1 updated to WP_001100753.1 blaPER inhibitor-resistant_class_A_extended-spectrum_beta-lactamase_PER-1 Protein Modified: WP_002317273.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_002317273.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR Protein Modified: WP_002368697.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_002368697.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR Protein Modified: WP_032489743.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_032489743.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR Protein Modified: WP_063856719.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_063856719.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR Protein Modified: WP_063856723.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_063856723.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR Protein Modified: WP_063856729.1 vanR-O VanO-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_063856729.1 vanR-O VanO-type_vancomycin_resistance_response_regulator_transcription_factor_VanR Protein Modified: WP_063860636.1 blaKPC carbapenem-hydrolyzing_class_A_beta-lactamase_KPC-14 updated to WP_063860636.1 blaKPC inhibitor-resistant_class_A_extended-spectrum_beta-lactamase_KPC-14 - AMR HMM library Changes: Total: Added 5 Total: Prev. Release 610 Total: Removed 12 Total: This Release 603 HMM Removed: NF000252.1 MexX HMM Removed: NF000282.2 RND_permease_1 HMM Removed: NF000314.1 adeB HMM Removed: NF000315.1 adeC-adeK-oprM HMM Removed: NF007842.1 PRK10555.1 HMM Removed: NF011706.2 PRK15127.1 HMM Removed: NF028537.1 P_eth_NH2_trans HMM Removed: NF033086.2 penta_rpt_Qnr HMM Removed: NF033134.0 cmlA_floR HMM Removed: NF033143.1 efflux_OM_AdeK HMM Removed: NF033643.1 EspJ_gen HMM Removed: NF033651.1 cyto_nec_fctrs HMM Added: NF000478.2 linco_LnuE HMM Added: NF012180.1 tet_MFS_43 HMM Added: NF033866.1 blaCDD HMM Added: NF033867.1 blaPAU HMM Added: NF033868.0 trim_DfrA36 - Protein family changes: Total: Added 11 Total: Prev. Release 1449 Total: Removed 6 Total: This Release 1454 Family Removed: NF011706.2 acrB Family Removed: NF007842.1 acrD Family Removed: NF000314.1 adeB/adeJ Family Removed: NF033143.1 adeK Family Removed: - lamda Family Removed: - lamda-2 Family Added: - aadA1bt Family Added: - arsB Family Added: - arsB_R773 Family Added: NF033866.1 blaCDD Family Added: NF033867.1 blaPAU Family Added: NF033868.0 dfrA36 Family Added: - emrD3 Family Added: - lambda Family Added: - lambda-2 Family Added: NF000478.2 lnu(E) Family Added: NF012180.1 tet(43) Family Changed: NF030466.1 MerP_Gneg updated to TIGR02052.1 MerP_Gneg Family Changed: NF030467.1 merA updated to TIGR02053.1 merA --------------------------------------------------------------------- Changes included in 2019-06-18.1 --------------------------------------------------------------------- This the first alpha release of the AMRFinderPlus database. For this and all following releases there is a distinction between "core" proteins which correspond to the genes that would previously have been reported by AMRFinder and "plus" proteins that are new genes and classes of genes. The "core" designation is given to proteins where we believe their presence is likely to have an important effect on antimicrobial resistance. * Screen for select point mutations for antibiotic resistance from Salmonella, E. coli, and Campylobacter * Protein mutations in: 50S_L22 protein, acrB, acrR, basR, cmeR, cyaA, fabG, fabI, folP, gyrA, gyrB, lon, marR, murA, nfsA, ompF, parC, parE, pmrA, pmrB, ptsI, ramR, rpoB, rpsL, soxR, soxS, tufA, uhpA, uhpT * Nucleotide mutations in 16S and 23S rRNA * Included point mutations are listed in the reference gene database (https://www.ncbi.nlm.nih.gov/pathogens/isolates#/refgene/) * New "Plus" genes * virulence factors * biocide resistance * metal resistance * heat resistance * acid resistance * Combined and integrated results from nucleotide and protein searches File formats have changed significantly. See https://github.com/evolarjun/amr/wiki for details. Since release 2019-04-29.1 only one change has been made to the core AMR proteins. Qac's are now categorized under Type STRESS and Subtype BIOCIDE. - Protein changes: Prev. Release: 4942 This Release: 5718 Added: 776 Modified: 0 Protein Added: ABF69110.1 eae intimin type beta Protein Added: ABF69117.1 eae intimin type epsilon Protein Added: ABF69121.1 eae intimin type epsilon Protein Added: ABF69122.1 eae intimin type alpha Protein Added: KYU89760.1 subB subtilase AB5 cytotoxin subunit B Protein Added: AAG16664.1 perA BFP system transcriptional regulator PerA Protein Added: AAG16667.1 perA BFP system transcriptional regulator PerA Protein Added: AAG16676.1 perA BFP system transcriptional regulator PerA Protein Added: AAB09625.1 arsD arsenite efflux transporter metallochaperone ArsD Protein Added: AAB09626.1 arsA arsenite efflux transporter ATPase subunit ArsA Protein Added: CAJ76690.1 stx1Aa Shiga toxin Stx1a subunit A Protein Added: CAJ76692.1 stx1Aa Shiga toxin Stx1a subunit A Protein Added: AAA98291.1 terC tellurium resistance membrane protein TerC Protein Added: AAA98293.1 terE tellurium resistance cAMP binding protein TerE Protein Added: AAG27731.1 norM sodium-coupled multidrug efflux MATE transporter NorM Protein Added: ABF02983.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: ABF04028.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: BAE98279.1 bfpA bundle-forming pilus major subunit BfpA Protein Added: BAE98281.1 bfpA bundle-forming pilus major subunit BfpA Protein Added: CAC14596.1 smeF multidrug efflux RND transporter outer membrane subunit SmeF Protein Added: AAA83973.1 merR1 mercury resistance transcriptional regulator MerR1 Protein Added: AAA83975.1 merT mercuric transport protein MerT Protein Added: AAA98292.1 terD tellurium resistance membrane protein TerD Protein Added: AAG34504.1 perA BFP system transcriptional regulator PerA Protein Added: APX31172.1 yfdX1 heat resistance protein YfdX1 Protein Added: APX31174.1 hdeD-GI heat resistance membrane protein HdeD-GI Protein Added: APX31176.1 trxLHR heat resistance system thioredoxin Trx-GI Protein Added: APX31177.1 kefB-GI heat resistance system K+/H+ antiporter KefB-GI Protein Added: APX31178.1 psi-GI heat resistance protein PsiE-GI Protein Added: AAA85087.1 f17a F17A fimbrial adhesin Protein Added: AAA85196.1 cnf1 cytotoxic necrotizing factor CNF1 Protein Added: AAG37043.1 espC serine protease autotransporter toxin EspC Protein Added: ABI93207.1 fedF F18 fimbrial adhesin subunit FedF Protein Added: BAF33872.1 capU putative hexosyltransferase CapU Protein Added: BAF33878.1 aggR aggregative adherence transcriptional regulator AggR Protein Added: BAF33885.1 sepA serine protease autotransporter toxin SepA Protein Added: BAF33888.1 agg4D aggregative adherence fimbria 4 chaperone Agg4D/HdaD Protein Added: BAF33891.1 agg4A aggregative adherence fimbria 4 major subunit Agg4A/HdaA Protein Added: BAF33901.1 aatA dispersin export ABC transporter outer membrane protein AatA Protein Added: BAF34018.1 aap dispersin Aap Protein Added: ABJ00546.1 iss increased serum survival lipoprotein Iss Protein Added: ABJ02430.1 ireA TonB-dependent siderophore receptor IreA Protein Added: OPH66324.1 lpfA1 long polar fimbria major subunit LpfA1 Protein Added: ABJ90288.1 fedF F18 fimbrial adhesin subunit FedF Protein Added: AAA86846.1 terZ tellurium resistance-associated protein TerZ Protein Added: ABC67318.2 stx2Aa Shiga toxin Stx2a subunit A Protein Added: AAG40758.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAA88371.1 merE broad-spectrum mercury transporter MerE Protein Added: AAG42788.1 perA BFP system transcriptional regulator PerA Protein Added: ASF80766.1 yfdX2 heat resistance protein YfdX2 Protein Added: ASF80771.1 shsP small heat shock protein sHSP20-GI Protein Added: CAM11313.1 nleA type III secretion system effector NleA Protein Added: CAM11314.1 nleA type III secretion system effector NleA Protein Added: CAM11315.1 nleA type III secretion system effector NleA Protein Added: CAM11317.1 nleA type III secretion system effector NleA Protein Added: CAM11321.1 nleA type III secretion system effector NleA Protein Added: CAM11323.1 nleA type III secretion system effector NleA Protein Added: CAM11324.1 nleA type III secretion system effector NleA Protein Added: CAM11325.1 nleA type III secretion system effector NleA Protein Added: AAA92618.1 f17a F17A fimbrial adhesin Protein Added: AAA92621.1 f17g F17G fimbrial adhesin Protein Added: AAA93060.1 arsD arsenite efflux transporter metallochaperone ArsD Protein Added: AAG53662.1 perA BFP system transcriptional regulator PerA Protein Added: BAF45432.1 tccP Tir-cytoskeleton coupling protein TccP Protein Added: BAF45437.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF45439.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF45440.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF45447.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF45451.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF45459.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: ABM90581.1 perA BFP system transcriptional regulator PerA Protein Added: ABM90583.1 perA BFP system transcriptional regulator PerA Protein Added: ABM90587.1 perA BFP system transcriptional regulator PerA Protein Added: ABM90589.1 perA BFP system transcriptional regulator PerA Protein Added: ABM90597.1 perA BFP system transcriptional regulator PerA Protein Added: ABM90605.1 perA BFP system transcriptional regulator PerA Protein Added: ABM90615.1 perA BFP system transcriptional regulator PerA Protein Added: AAC46147.1 yfeA iron/manganese ABC transporter substrate-binding protein YfeA Protein Added: AAC46148.1 yfeB iron/manganese ABC transporter ATP-binding protein YfeB Protein Added: AAC46150.1 yfeD iron/manganese ABC transporter permease subunit YfeD Protein Added: ATE69525.1 acr3 arsenite efflux transporter Acr3 Protein Added: AAG55141.1 nleC type III secretion system effector zinc metalloprotease NleC Protein Added: AAG56990.1 espJ type III secretion system effector ADP-ribosyltransferase EspJ Protein Added: AAG58695.1 lpfA1 long polar fimbria major subunit LpfA1 Protein Added: AAG58814.1 espF type III secretion system LEE effector EspF Protein Added: AAG58818.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: AAG58825.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAK15050.1 ttgR efflux transport transcriptional regulator TtgR Protein Added: AAK16940.1 nleA type III secretion system effector NleA Protein Added: AAK17180.1 nfaE Dr family non-fimbrial adhesin I chaperone NfaE Protein Added: AAK18385.1 sepA serine protease autotransporter toxin SepA Protein Added: AAK18444.1 ipaD type III secretion system needle tip complex protein IpaD Protein Added: BAB37280.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: BAB38093.1 lpfA2 long polar fimbria major subunit LpfA2 Protein Added: AAC44736.1 terW tellurium resistance protein TerW Protein Added: AVL28824.1 aar AggR-activated transcriptional regulator Aar Protein Added: SPD96882.1 silS copper/silver sensor histidine kinase SilS Protein Added: SPD96883.1 silR copper/silver response regulator transcription factor SilR Protein Added: SPD96884.1 silC Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC Protein Added: CAA57177.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAA57175.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAA57173.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAA57171.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: BAB43874.1 cadD cadmium resistance transporter CadD Protein Added: AAK48830.1 cadR cadmium resistance transcriptional regulator CadR Protein Added: BAF52034.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52035.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52033.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52358.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52360.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52362.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52363.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52364.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52365.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52366.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52367.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52370.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52374.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52377.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52548.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: BAF52549.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: BAB47641.1 merB organomercurial lyase MerB Protein Added: AAK56853.1 chrR class I chromate reductase ChrR Protein Added: CAC39286.1 espI serine protease autotransporter EspI Protein Added: AAA83977.1 merA mercury(II) reductase Protein Added: AAA23405.1 fasA F6 fimbrial major subunit FasA Protein Added: AAA23421.1 fim41a fimbrial adhesin F41 protein Fim41a Protein Added: AAK66972.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAC41416.1 cfaC CFA/I pilus usher protein CfaC Protein Added: CAB54534.2 mchB microcin H47 Protein Added: AAK69562.1 srpS solvent efflux transporter transcriptional repressor SrpS Protein Added: AAA23734.1 fedA F18 fimbrial major subunit FedA Protein Added: ABQ02454.1 eae intimin type rho Protein Added: AAA24032.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: AAA24035.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: AAA24390.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: AXV27948.1 agg3C aggregative adherence fimbria 3 usher protein Agg3C Protein Added: AAA19189.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: AAA19190.1 stx2Be Shiga toxin Stx2e subunit B Protein Added: AAA24632.1 stx2Af Shiga toxin Stx2f subunit A Protein Added: AAA24633.1 stx2Bf Shiga toxin Stx2f subunit B Protein Added: AAA71893.1 stx1Aa Shiga toxin Stx1a subunit A Protein Added: AAA71894.1 stx1Ba Shiga toxin Stx1a subunit B Protein Added: AAA24653.1 sta1 heat-stable enterotoxin ST-I group a Protein Added: ABR09925.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: ABR09934.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: ABR09935.1 stx2Bc Shiga toxin Stx2c subunit B Protein Added: ABR09936.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: ABR09937.1 stx2Bd Shiga toxin Stx2d subunit B Protein Added: ABR09945.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: ABR09961.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: ABR09963.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: ABR10024.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: CAA30714.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: CAA30715.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: AAB59075.1 merT mercuric transport protein MerT Protein Added: AAA88369.1 merB organomercurial lyase MerB Protein Added: AAA88370.1 merD mercury resistance co-regulator MerD Protein Added: AAA98222.1 merT mercuric transport protein MerT Protein Added: AAA98223.1 merP mercury resistance system periplasmic binding protein MerP Protein Added: AAA25638.1 arsC thioredoxin-dependent arsenate reductase Protein Added: AAA88432.1 chrA chromate resistance efflux protein ChrA Protein Added: AAA25803.1 copR heavy metal response regulator transcription factor CopR Protein Added: AAA25804.1 copS copper resistance membrane spanning protein CopS Protein Added: AAA25806.1 copA laccase-like oxidase CopA Protein Added: AAA25807.1 copB copper-binding protein CopB Protein Added: CAC48396.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: CAC48398.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: AAA21094.1 arsA arsenite efflux transporter ATPase subunit ArsA Protein Added: BAB62897.1 cofA type IV pilus CFA/III major pilin Protein Added: BAB62907.1 cofA type IV pilus CFA/III major pilin Protein Added: CAA63849.1 ehxA enterohemolysin Protein Added: AAA26402.1 klaB tellurium resistance system protein klaB Protein Added: AAA26403.1 klaC tellurium resistance system protein klaC Protein Added: AAK97136.1 cfaC CFA/I pilus usher protein CfaC Protein Added: AAK99679.1 pmrA multidrug efflux MFS transporter PmrA Protein Added: CAC69248.1 merR mercury resistance transcriptional regulator MerR Protein Added: CAC69249.1 merT mercuric transport protein MerT Protein Added: CAC69250.1 merP mercury resistance system periplasmic binding protein MerP Protein Added: CAC69251.1 merA mercury(II) reductase Protein Added: BAB64566.1 bexA multidrug efflux MATE transporter BexA Protein Added: AAA27589.1 arsC thioredoxin-dependent arsenate reductase Protein Added: ABU55302.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: BAF76383.1 ttgA toluene efflux RND transporter periplasmic adaptor subunit TtgA Protein Added: BAF76384.1 ttgB multidrug efflux RND transporter permease subunit TtgB Protein Added: ABV01314.1 ltcA heat-labile enterotoxin LT subunit A Protein Added: BAF79679.1 smdA multidrug efflux ABC transporter permease/ATP-binding subunit SmdA Protein Added: BAF79680.1 smdB multidrug efflux ABC transporter permease/ATP-binding subunit SmdB Protein Added: ABV16438.1 eatA serine protease autotransporter toxin EatA Protein Added: BAB68369.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: BAB68370.1 stx2Bc Shiga toxin Stx2c subunit B Protein Added: BAF80121.1 ssmE multidrug efflux SMR transporter SsmE Protein Added: AAL06376.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAL06381.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: AAL06387.1 espF type III secretion system LEE effector EspF Protein Added: AAC23256.1 hmrM sodium-coupled multidrug efflux MATE transporter HmrM Protein Added: ABQ02442.1 ehxA enterohemolysin Protein Added: ABQ02443.1 ehxA enterohemolysin Protein Added: ABQ02445.1 ehxA enterohemolysin Protein Added: ABQ02447.1 ehxA enterohemolysin Protein Added: ABQ02448.1 ehxA enterohemolysin Protein Added: AAL08400.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: BAF92845.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAL14441.1 adeC multidrug efflux RND transporter AdeABC outer membrane channel subunit AdeC Protein Added: CAP17609.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAP17610.1 stx2Be Shiga toxin Stx2e subunit B Protein Added: AAL18821.1 epeA serine protease autotransporter EpeA Protein Added: AAL19305.1 mdsB multidrug efflux RND transporter permease subunit MdsB Protein Added: AAL19306.1 mdsA multidrug efflux RND transporter periplasmic adaptor subunit MdsA Protein Added: AAL19307.1 golT gold/copper-translocating P-type ATPase GolT Protein Added: AAL19308.1 golS Au(I) sensor transcriptional regulator GolS Protein Added: BAF96525.1 espJ type III secretion system effector ADP-ribosyltransferase EspJ Protein Added: BAF96538.1 nleB2 type III secretion system effector arginine glycosyltransferase NleB2 Protein Added: BAF96541.1 nleA type III secretion system effector NleA Protein Added: BAA18405.1 acr3 arsenite efflux transporter Acr3 Protein Added: BAA18407.1 arsC thioredoxin-dependent arsenate reductase Protein Added: AAL26283.1 saa autoagglutinating adhesin Saa Protein Added: CAA65654.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: AAC45964.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: AAC45965.1 stx2Be Shiga toxin Stx2e subunit B Protein Added: ACA34793.1 tsh temperature-sensitive protease autotransporter hemagglutinin Tsh Protein Added: BAG11995.1 tccP Tir-cytoskeleton coupling protein TccP Protein Added: BAG11997.1 tccP Tir-cytoskeleton coupling protein TccP Protein Added: BAG12001.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: ACB16424.1 lpfA long polar fimbria major subunit LpfA-O113 Protein Added: ACB16655.1 eilA HilA family transcriptional regulator EilA Protein Added: ACB17037.1 air inverse autotransporter adhesin EaeX/Air Protein Added: CAA70196.1 merT mercuric transport protein MerT Protein Added: ACB72721.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: AAC44731.1 espC serine protease autotransporter toxin EspC Protein Added: AAC74250.1 ymgB biofilm/acid-resistance regulator AriR Protein Added: AAC76298.1 acrF multidrug efflux RND transporter permease subunit AcrF Protein Added: AAC77293.1 mdtM multidrug efflux MFS transporter MdtM Protein Added: AAL57565.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: BAB82994.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: BAB82996.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: BAB82998.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: BAB83000.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: BAB83002.1 stx2Ag Shiga toxin Stx2g subunit A Protein Added: BAB83003.1 stx2Bg Shiga toxin Stx2g subunit B Protein Added: BAB83005.1 stx2Bb Shiga toxin Stx2b subunit B Protein Added: BAB83007.1 stx2Bb Shiga toxin Stx2b subunit B Protein Added: BAB83020.1 stx2Ag Shiga toxin Stx2g subunit A Protein Added: BAB83022.1 stx1Ac Shiga toxin Stx1c subunit A Protein Added: BAB83023.1 stx1Bc Shiga toxin Stx1c subunit B Protein Added: BAB83024.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: AAL72309.1 sepA serine protease autotransporter toxin SepA Protein Added: AAL72350.1 ipaD type III secretion system needle tip complex protein IpaD Protein Added: AAL05407.1 tcrB copper-translocating P-type ATPase TcrB Protein Added: ACD06066.1 capU putative hexosyltransferase CapU Protein Added: ACD06132.1 ipaD type III secretion system needle tip complex protein IpaD Protein Added: ACD07996.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 Protein Added: ACD09076.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: BAA11821.1 chrR class I chromate reductase ChrR Protein Added: CAQ45062.1 emrC multidrug efflux transporter outer membrane subunit EmrC Protein Added: CAQ45063.1 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA Protein Added: CAQ45064.1 emrB multidrug efflux MFS transporter permease subunit EmrB Protein Added: ACF05260.1 agg4A aggregative adherence fimbria 4 major subunit Agg4A/HdaA Protein Added: ACF30254.1 mtrR multidrug efflux system transcriptional repressor MtrR Protein Added: ACF30256.1 mtrF AbgT family antimetabolite efflux transporter MtrF Protein Added: BAG66379.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAG66729.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: BAG66736.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: ACG59623.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: ACG59674.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: ACG59676.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: ACG59681.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: ACG59730.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: ACG59732.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: ACG59737.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: ACG76368.1 arsP organoarsenical efflux permease ArsP Protein Added: ACI12150.1 terB tellurium resistance membrane protein TerB Protein Added: BAG76115.1 iss increased serum survival lipoprotein Iss Protein Added: AAA98099.1 stx1Aa Shiga toxin Stx1a subunit A Protein Added: CAS08589.1 nleB2 type III secretion system effector arginine glycosyltransferase NleB2 Protein Added: CAS08990.1 nleA type III secretion system effector NleA Protein Added: CAS10463.1 espC serine protease autotransporter toxin EspC Protein Added: CAS06720.1 eae intimin type gamma Protein Added: CAS06721.1 eae intimin type alpha Protein Added: CAS06723.1 eae intimin type alpha Protein Added: BAA20334.1 merR mercury resistance transcriptional regulator MerR Protein Added: BAA20336.1 merP mercury resistance system periplasmic binding protein MerP Protein Added: BAA20337.1 merA mercury(II) reductase Protein Added: AAM70045.1 stx2Aa Shiga toxin Stx2a subunit A Protein Added: CAQ87187.1 iroN siderophore salmochelin receptor IroN Protein Added: CAV00478.1 lpfA long polar fimbria major subunit LpfA Protein Added: CAV00812.1 lpfA long polar fimbria major subunit LpfA-O113 Protein Added: CAV02025.1 capU putative hexosyltransferase CapU Protein Added: CAQ90194.1 iss increased serum survival lipoprotein Iss Protein Added: CAU95796.1 aatA dispersin export ABC transporter outer membrane protein AatA Protein Added: CAU95824.1 agg3D aggregative adherence fimbria 3 chaperone Agg3D Protein Added: CAQ97644.1 iss increased serum survival lipoprotein Iss Protein Added: CAR01635.1 vactox vacuolating autotransporter toxin Vat Protein Added: CAR09703.2 ireA TonB-dependent siderophore receptor IreA Protein Added: CAR12622.1 iss increased serum survival lipoprotein Iss Protein Added: CAR15326.1 air inverse autotransporter adhesin EaeX/Air Protein Added: CAW30811.1 nfaE Dr family non-fimbrial adhesin I chaperone NfaE Protein Added: CAW30815.1 nfaE Dr family non-fimbrial adhesin I chaperone NfaE Protein Added: ACL13561.1 copR heavy metal response regulator transcription factor CopR Protein Added: ACL13562.1 copS copper resistance membrane spanning protein CopS Protein Added: ACL51961.1 ehxA enterohemolysin Protein Added: ACL51990.1 toxB toxin B Protein Added: AAM88296.1 agg3C aggregative adherence fimbria 3 usher protein Agg3C Protein Added: AAM88297.1 agg3B aggregative adherence fimbria 3 minor subunit Agg3B Protein Added: AAM88298.1 agg3A aggregative adherence fimbria 3 major subunit Agg3A Protein Added: AAM88299.1 astA heat-stable enterotoxin EAST1 Protein Added: AAM88302.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: BAA14138.2 merC organomercurial transporter MerC Protein Added: AAM88668.1 cueA copper resistance metal-translocating P1-type ATPase CueA Protein Added: AAM90978.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: CAX18553.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: CAX18626.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: CAX18635.1 espF type III secretion system LEE effector EspF Protein Added: CAX18641.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAX18646.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: CAX18721.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAX18726.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: ACM67143.1 eae intimin type alpha Protein Added: ACM67145.1 eae intimin type iota Protein Added: ACM67146.1 eae intimin type alpha Protein Added: ACM67148.1 eae intimin type gamma Protein Added: ACM67149.1 eae intimin type gamma Protein Added: ACM67152.1 eae intimin type beta Protein Added: ACM67153.1 eae intimin type lambda Protein Added: ACM67154.1 eae intimin type gamma Protein Added: ACM67155.1 eae intimin type epsilon Protein Added: ACM67156.1 eae intimin type epsilon Protein Added: ACM67157.1 eae intimin type beta Protein Added: ACM67158.1 eae intimin type epsilon Protein Added: ACM67160.1 eae intimin type beta Protein Added: ACM67161.1 eae intimin type beta Protein Added: ACM67162.1 eae intimin type gamma Protein Added: ACM67163.1 eae intimin type rho Protein Added: ACM67164.1 eae intimin type gamma Protein Added: ACM67165.1 eae intimin type gamma Protein Added: ACM67166.1 eae intimin type gamma Protein Added: ACM67167.1 eae intimin type epsilon Protein Added: ACM67168.1 eae intimin type alpha Protein Added: ACM67169.1 eae intimin type gamma Protein Added: ACM67172.1 eae intimin type epsilon Protein Added: ACM67177.1 eae intimin type gamma Protein Added: ACM67178.1 eae intimin type epsilon Protein Added: BAH24012.1 toxB toxin B Protein Added: CAB14520.2 acr3 arsenite efflux transporter Acr3 Protein Added: ACO06752.1 emhB efflux RND transporter permease subunit EmhB Protein Added: AAN03785.1 cnf1 cytotoxic necrotizing factor CNF1 Protein Added: AAN03786.1 cnf1 cytotoxic necrotizing factor CNF1 Protein Added: AAN04250.1 dpsA non-specific DNA-binding protein DpsA Protein Added: BAC10987.1 stx1Ac Shiga toxin Stx1c subunit A Protein Added: BAC10988.1 stx1Bc Shiga toxin Stx1c subunit B Protein Added: BAC10992.1 stx1Bc Shiga toxin Stx1c subunit B Protein Added: CAY54182.1 bfpA bundle-forming pilus major subunit BfpA Protein Added: AAN29240.1 bepD multidrug efflux RND transporter periplasmic adaptor subunit BepD Protein Added: AAN29241.1 bepE multidrug efflux RND transporter permease subunit BepE Protein Added: AAN29871.1 bepC multidrug efflux RND transporter outer membrane subunit BepC Protein Added: AAN33534.1 bepG multidrug efflux RND transporter permease subunit BepG Protein Added: AAN33535.1 bepF multidrug efflux RND transporter periplasmic adaptor subunit BepF Protein Added: CAD48850.1 cdtB cytolethal distending toxin type III/V nuclease subunit CdtB Protein Added: CAC86907.1 merB organomercurial lyase MerB Protein Added: BAH65949.1 iroN siderophore salmochelin receptor IroN Protein Added: BAH72965.1 cdtB cytolethal distending toxin type II nuclease subunit CdtB Protein Added: AAN42986.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 Protein Added: AAN43435.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: AAN44449.1 sigA serine protease autotransporter toxin SigA Protein Added: CAQ68302.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: ACS88189.1 ipaD type III secretion system needle tip complex protein IpaD Protein Added: AAC45719.1 f17a F17A fimbrial adhesin Protein Added: AAC45722.1 f17g F17G fimbrial adhesin Protein Added: AAN68576.1 mrdH Ni(II)/Co(II) efflux transporter permease subunit MrdH Protein Added: AAN68577.1 mreA metal-sensing transcriptional repressor MreA Protein Added: ACT33468.1 f17a F17A fimbrial adhesin Protein Added: ACT33471.1 f17g F17G fimbrial adhesin Protein Added: ACT72391.1 tccP Tir-cytoskeleton coupling protein TccP Protein Added: CAR47993.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAR48009.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: BAH86759.1 stx2Af Shiga toxin Stx2f subunit A Protein Added: BAH86760.1 stx2Bf Shiga toxin Stx2f subunit B Protein Added: BAA20338.2 merB organomercurial lyase MerB Protein Added: ACU32684.1 stx2Aa Shiga toxin Stx2a subunit A Protein Added: ACU65296.1 merA mercury(II) reductase Protein Added: CAX45702.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAX45706.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: CAX45714.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAX45718.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAX45737.1 stx2Bd Shiga toxin Stx2d subunit B Protein Added: CAX45739.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: CAX45746.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: CAX51714.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: AAB82330.1 aafA aggregative adherence fimbria II major subunit AafA Protein Added: BAI25473.1 nleC type III secretion system effector zinc metalloprotease NleC Protein Added: BAI31154.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAI32292.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: BAI32327.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: BAI32516.1 espI serine protease autotransporter EspI Protein Added: BAI33940.1 etpD variant type II secretion system secretin EtpD Protein Added: BAI36256.1 nleC type III secretion system effector zinc metalloprotease NleC Protein Added: BAI36790.1 nleA type III secretion system effector NleA Protein Added: BAI37513.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: BAI37519.1 espF type III secretion system LEE effector EspF Protein Added: BAI37525.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: BAA23166.1 merG phenylmercury resistance protein MerG Protein Added: AAN76093.1 iroN siderophore salmochelin receptor IroN Protein Added: AAN77057.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAN77061.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAN77063.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: BAI44131.1 agg5A aggregative adherence fimbria V major subunit Agg5A Protein Added: AAD12176.1 srpB solvent efflux RND transporter permease subunit SrpB Protein Added: AAD12177.1 ttgI solvent efflux RND transporter outer membrane subunit SrpC Protein Added: AAD12178.1 srpA solvent efflux RND transporter periplasmic adaptor subunit SrpA Protein Added: AAN78874.1 vactox vacuolating autotransporter toxin Vat Protein Added: AAN79707.1 iroN siderophore salmochelin receptor IroN Protein Added: AAN80033.1 iss increased serum survival lipoprotein Iss Protein Added: AAN83596.1 ireA TonB-dependent siderophore receptor IreA Protein Added: CAB14519.1 arsC thioredoxin-dependent arsenate reductase Protein Added: AAB91079.1 copB copper-binding protein CopB Protein Added: CAA05105.1 copP copper-binding metallochaperone CopP Protein Added: AAB88410.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: EEZ94110.1 sdeA multidrug efflux RND transporter periplasmic adaptor subunit SdeA Protein Added: AAO17297.1 eatA serine protease autotransporter toxin EatA Protein Added: ADA73787.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 Protein Added: ADA76801.1 sepA serine protease autotransporter toxin SepA Protein Added: AAO19475.1 stx1Ad Shiga toxin Stx1d subunit A Protein Added: AAO19476.1 stx1Bd Shiga toxin Stx1d subunit B Protein Added: ADA79992.1 merT mercuric transport protein MerT Protein Added: CBG87859.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: CBG89712.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAD66214.1 vactox vacuolating autotransporter toxin Vat Protein Added: ADB20445.1 toxB toxin B Protein Added: CBG36837.1 eilA HilA family transcriptional regulator EilA Protein Added: CBG36838.1 air inverse autotransporter adhesin EaeX/Air Protein Added: CBG37385.1 aaiC type VI secretion system protein AaiC/Hcp2 Protein Added: CBG27762.1 aatA dispersin export ABC transporter outer membrane protein AatA Protein Added: CBG27784.1 aafB aggregative adherence fimbria II minor subunit AafB Protein Added: CBG27798.1 aafD aggregative adherence fimbria II chaperone AafD Protein Added: CBG27800.1 aafA aggregative adherence fimbria II major subunit AafA Protein Added: CBG27804.1 aggR aggregative adherence transcriptional regulator AggR Protein Added: CBG27807.1 aap dispersin Aap Protein Added: CBG27812.1 aar AggR-activated transcriptional regulator Aar Protein Added: AAD12174.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: AAO49780.1 ttgD toluene efflux RND transporter periplasmic adaptor subunit TtgD Protein Added: AAC38390.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAC38394.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: AAC38400.1 espF type III secretion system LEE effector EspF Protein Added: BAA24822.1 arsA arsenite efflux transporter ATPase subunit ArsA Protein Added: AAA20885.1 astA heat-stable enterotoxin EAST1 Protein Added: AAA23736.1 f17g F17G fimbrial adhesin Protein Added: AAA23737.1 f17a F17A fimbrial adhesin Protein Added: ADD58872.1 espF type III secretion system LEE effector EspF Protein Added: ADD58881.1 eae intimin type gamma Protein Added: ADD58883.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: EFF39147.1 norM sodium-coupled multidrug efflux MATE transporter NorM Protein Added: AAO66617.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: BAJ04486.1 perA BFP system transcriptional regulator PerA Protein Added: BAJ04488.1 perA BFP system transcriptional regulator PerA Protein Added: AAC38219.1 merP mercury resistance system periplasmic binding protein MerP Protein Added: AAC38220.1 merA mercury(II) reductase Protein Added: AAC38221.1 merD mercury resistance co-regulator MerD Protein Added: ADE90928.1 vactox vacuolating autotransporter toxin Vat Protein Added: AAC38229.1 merR mercury resistance transcriptional regulator MerR Protein Added: AAC38230.1 merB organomercurial lyase MerB Protein Added: AAC38231.1 merT mercuric transport protein MerT Protein Added: AAC38232.1 merP mercury resistance system periplasmic binding protein MerP Protein Added: AAC38233.1 merC organomercurial transporter MerC Protein Added: AAC38236.1 merE broad-spectrum mercury transporter MerE Protein Added: ADF64798.1 ncrC Ni(II)/Co(II) efflux transporter permease subunit NcrC Protein Added: CBK85583.1 iroN siderophore salmochelin receptor IroN Protein Added: CBL93318.1 capU putative hexosyltransferase CapU Protein Added: CBL93506.1 lngA type IV pilus longus major pilin Protein Added: ADI59685.1 astA heat-stable enterotoxin EAST1 Protein Added: ADI95409.1 ttgE multidrug efflux RND transporter permease subunit TtgE Protein Added: ADI95411.1 ttgT efflux transport transcriptional regulator TtgT Protein Added: AAP03990.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: AAP18950.1 lpfA long polar fimbria major subunit LpfA-O113 Protein Added: ADK23698.1 qacR multidrug-binding transcriptional regulator QacR Protein Added: ADK73987.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAM22256.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAM22257.1 stx2Bd Shiga toxin Stx2d subunit B Protein Added: CAD56174.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: CAD56186.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: AAA16360.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: AAA16361.1 stx2Bb Shiga toxin Stx2b subunit B Protein Added: AAA16362.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: ADM83435.1 nleA type III secretion system effector NleA Protein Added: ADN71659.1 iss increased serum survival lipoprotein Iss Protein Added: AAP37403.1 stx2Ag Shiga toxin Stx2g subunit A Protein Added: AAC26634.1 pet serine protease autotransporter toxin Pet Protein Added: CBJ04488.1 cfaC CFA/I pilus usher protein CfaC Protein Added: AAC15683.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: ADO96486.1 hmrM sodium-coupled multidrug efflux MATE transporter HmrM Protein Added: ADP02162.1 merA mercury(II) reductase Protein Added: CAA73506.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: ADR26561.1 iss increased serum survival lipoprotein Iss Protein Added: ADR70747.1 copA laccase-like oxidase CopA Protein Added: ADR70748.1 copB copper-binding protein CopB Protein Added: BAC77251.1 sdeY multidrug efflux RND transporter permease subunit SdeY Protein Added: ADW66881.1 arsH arsenic resistance NADPH-dependent reductase ArsH Protein Added: AAP78989.1 ipaD type III secretion system needle tip complex protein IpaD Protein Added: BAC78639.1 stx1Aa Shiga toxin Stx1a subunit A Protein Added: BAC78640.1 stx1Ba Shiga toxin Stx1a subunit B Protein Added: AAC69314.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAC69318.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: BAJ79293.1 aafA aggregative adherence fimbria II major subunit AafA Protein Added: BAJ79295.1 aafA aggregative adherence fimbria II major subunit AafA Protein Added: BAJ79296.1 aafA aggregative adherence fimbria II major subunit AafA Protein Added: BAJ79297.1 aafA aggregative adherence fimbria II major subunit AafA Protein Added: BAJ79299.1 agg5A aggregative adherence fimbria V major subunit Agg5A Protein Added: BAJ79300.1 agg5A aggregative adherence fimbria V major subunit Agg5A Protein Added: ADY84088.1 nreB nickel resistance MFS transporter NreB Protein Added: AAC24352.1 ehxA enterohemolysin Protein Added: ADZ45128.1 ehxA enterohemolysin Protein Added: AAP88295.1 copA laccase-like oxidase CopA Protein Added: AEC46567.1 copA laccase-like oxidase CopA Protein Added: AEC46568.1 copB copper-binding protein CopB Protein Added: AAC38671.1 ttgB multidrug efflux RND transporter permease subunit TtgB Protein Added: BAA31774.1 ehxA enterohemolysin Protein Added: BAA31815.1 toxB toxin B Protein Added: BAA31832.1 katP catalase/peroxidase KatP Protein Added: BAA31836.1 espP serine protease autotransporter EspP Protein Added: AAQ17236.1 mco multi-copper oxidase Mco Protein Added: AAQ17546.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAA74174.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: AEG95593.1 iroN siderophore salmochelin receptor IroN Protein Added: AAQ20107.1 cfaC CFA/I pilus usher protein CfaC Protein Added: AEK01061.1 iroN siderophore salmochelin receptor IroN Protein Added: AAC31499.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: AAY90617.2 emhA efflux RND transporter periplasmic adaptor subunit EmhA Protein Added: CAA12346.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAA12348.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: AEM17342.1 cdtB cytolethal distending toxin nuclease subunit CdtB Protein Added: AAC33154.1 lngA type IV pilus longus major pilin Protein Added: AEQ14997.1 eilA HilA family transcriptional regulator EilA Protein Added: AEQ15694.1 capU putative hexosyltransferase CapU Protein Added: AAC33908.1 merC organomercurial transporter MerC Protein Added: CCE21264.1 agg3A aggregative adherence fimbria 3 major subunit Agg3A Protein Added: EHE72460.1 pmrA multidrug efflux MFS transporter PmrA Protein Added: EHF16244.1 aatA dispersin export ABC transporter outer membrane protein AatA Protein Added: EHF16297.1 aggB aggregative adherence fimbria I minor subunit AggB Protein Added: EHF16298.1 aggA aggregative adherence fimbria I major subunit AggA Protein Added: AET11941.1 nleA type III secretion system effector NleA Protein Added: AET11995.1 nleA type III secretion system effector NleA Protein Added: AET12008.1 nleA type III secretion system effector NleA Protein Added: BAL46940.1 eae intimin type alpha Protein Added: BAL46941.1 eae intimin type epsilon Protein Added: BAL47132.1 eae intimin type epsilon Protein Added: BAL47176.1 eae intimin type rho Protein Added: BAL47179.1 eae intimin type epsilon Protein Added: BAL47181.1 eae intimin type alpha Protein Added: AEZ42789.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AEZ43710.1 nleA type III secretion system effector NleA Protein Added: AAQ92182.1 emhC efflux RND transporter outer membrane subunit EmhC Protein Added: CAA77068.1 aggA aggregative adherence fimbria I major subunit AggA Protein Added: AAR02190.1 aggA aggregative adherence fimbria I major subunit AggA Protein Added: BAL72684.1 cdtB cytolethal distending toxin nuclease subunit CdtB Protein Added: BAL72697.1 cdtB cytolethal distending toxin nuclease subunit CdtB Protein Added: AAR12207.1 cdtB cytolethal distending toxin type III/V nuclease subunit CdtB Protein Added: AAC69584.1 ybtQ yersiniabactin ABC transporter ATP-binding/permease protein YbtQ Protein Added: AAR13270.1 iroN siderophore salmochelin receptor IroN Protein Added: AFH14350.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: CAD87828.1 sta1 heat-stable enterotoxin ST-I group a Protein Added: BAA34299.1 mexX multidrug efflux RND transporter periplasmic adaptor subunit MexX Protein Added: AFK88558.1 auto-sat serine protease autotransporter toxin Sat Protein Added: AFM31243.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: AFM70729.1 copA copper-translocating P-type ATPase CopA Protein Added: AFM70730.1 copB copper/silver-translocating P-type ATPase CopB Protein Added: AAC82360.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: AAR82963.1 nirA nickel resistance membrane nickel efflux protein NirA Protein Added: AAR82964.1 nirB nickel-sensing transcriptional repressor NirB Protein Added: AAR82966.1 nirD nickel resistance OB fold protein NirD Protein Added: AFQ65076.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: CAA50007.1 cnf1 cytotoxic necrotizing factor CNF1 Protein Added: CAA12345.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAA12350.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAA12351.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: AFS59871.1 sepA serine protease autotransporter toxin SepA Protein Added: AFS85685.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: AAC99337.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAA21388.1 ybtP yersiniabactin ABC transporter ATP-binding/permease protein YbtP Protein Added: BAA36431.1 merR mercury resistance transcriptional regulator MerR Protein Added: BAA36433.1 merD mercury resistance co-regulator MerD Protein Added: CAA40744.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: CAA23532.1 ltcA heat-labile enterotoxin LT subunit A Protein Added: CAA32535.1 fim41a fimbrial adhesin F41 protein Fim41a Protein Added: AAD05936.1 copP copper-binding metallochaperone CopP Protein Added: AAS07580.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAS07581.1 stx2Bc Shiga toxin Stx2c subunit B Protein Added: AAS07582.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAS07586.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAS07588.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAS07589.1 stx2Bd Shiga toxin Stx2d subunit B Protein Added: AAS07590.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAS07596.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAS07600.1 stx2Aa Shiga toxin Stx2a subunit A Protein Added: AAS07606.1 stx2Aa Shiga toxin Stx2a subunit A Protein Added: AAD11743.1 silE silver-binding protein SilE Protein Added: AAD11746.1 silC Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC Protein Added: AAD11748.1 silB Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB Protein Added: AAD11749.1 silA Cu(+)/Ag(+) efflux RND transporter permease subunit SilA Protein Added: AAD11750.1 silP Ag(+)-translocating P-type ATPase SilP Protein Added: AFX83959.1 subA subtilase AB5 cytotoxin subunit A Protein Added: AAS21297.1 tbtR tribuytltin resistance regulator TbtR Protein Added: CAA43585.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAD15663.1 tbtA multidrug efflux RND transporter periplasmic adaptor subunit TbtA Protein Added: AAD15664.1 tbtB multidrug efflux RND transporter permease subunit TbtB Protein Added: AAD15665.1 tbtM multidrug efflux RND transporter outer membrane channel subunit TbtM Protein Added: AAD17509.1 f17a F17A fimbrial adhesin Protein Added: AAD17510.1 f17a F17A fimbrial adhesin Protein Added: AAD17511.1 f17a F17A fimbrial adhesin Protein Added: AAD17513.1 f17g F17G fimbrial adhesin Protein Added: AAD17514.1 f17g F17G fimbrial adhesin Protein Added: AAD17515.1 f17g F17G fimbrial adhesin Protein Added: AAA18786.1 cdtB cytolethal distending toxin type II nuclease subunit CdtB Protein Added: CAA77320.1 merR mercury resistance transcriptional regulator MerR Protein Added: CAA77324.1 merD mercury resistance co-regulator MerD Protein Added: CAA77325.1 merE broad-spectrum mercury transporter MerE Protein Added: CAA81047.1 mtrR multidrug efflux system transcriptional repressor MtrR Protein Added: AAA74436.1 mexA multidrug efflux RND transporter periplasmic adaptor subunit MexA Protein Added: AGC14252.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: AAS47019.1 nleC type III secretion system effector zinc metalloprotease NleC Protein Added: AGC85979.1 iss increased serum survival lipoprotein Iss Protein Added: CCG33322.1 iroN siderophore salmochelin receptor IroN Protein Added: AAS50165.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: AAO18187.2 sdeB multidrug efflux RND transporter permease subunit SdeB Protein Added: AAA98221.1 merR mercury resistance transcriptional regulator MerR Protein Added: AAS76847.1 fedA F18 fimbrial major subunit FedA Protein Added: AAD25959.1 merR2 mercury resistance transcriptional regulator MerR2 Protein Added: AAA98245.1 merA mercury(II) reductase Protein Added: AAD27810.1 aafC aggregative adherence fimbria II usher protein AafC Protein Added: AAA24698.1 tsh temperature-sensitive protease autotransporter hemagglutinin Tsh Protein Added: CAE82650.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: CAE82653.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: CAE82670.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: AAD28079.1 hlyE hemolysin HlyE Protein Added: CAA83535.1 aggR aggregative adherence transcriptional regulator AggR Protein Added: EMS03085.1 aggA aggregative adherence fimbria I major subunit AggA Protein Added: CAE55775.1 auto-sat serine protease autotransporter toxin Sat Protein Added: AAT36311.1 rpeA serine protease autotransporter colonization factor RpeA Protein Added: BAA77749.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: BAA77750.1 stx2Bb Shiga toxin Stx2b subunit B Protein Added: BAA77751.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: CAA46767.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: CAA46768.1 stx2Bb Shiga toxin Stx2b subunit B Protein Added: CAA77936.1 emrE multidrug efflux SMR transporter EmrE Protein Added: AAT65972.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAT66000.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAT66010.1 stx2Aa Shiga toxin Stx2a subunit A Protein Added: AAT66011.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: AAT66012.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AGL46515.1 merF mercury resistance system transport protein MerF Protein Added: AAT68784.1 subB subtilase AB5 cytotoxin subunit B Protein Added: AAT68785.1 subA subtilase AB5 cytotoxin subunit A Protein Added: AAT76975.1 lpfA long polar fimbria major subunit LpfA-O113 Protein Added: AAD39553.1 ttgA toluene efflux RND transporter periplasmic adaptor subunit TtgA Protein Added: AAU01878.1 sepA serine protease autotransporter toxin SepA Protein Added: AAN38824.2 adeE multidrug efflux RND transporter permease subunit AdeE Protein Added: AAU10477.1 adeD multidrug efflux RND transporter periplasmic adaptor subunit AdeD Protein Added: AAU88208.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAU88264.1 cdtB cytolethal distending toxin nuclease subunit CdtB Protein Added: AAA57451.1 aggD aggregative adherence fimbria I chaperone AggD Protein Added: AAA57452.1 aggC aggregative adherence fimbria I usher protein AggC Protein Added: AAA57453.1 aggB aggregative adherence fimbria I minor subunit AggB Protein Added: AAA57454.1 aggA aggregative adherence fimbria I major subunit AggA Protein Added: CAA85366.1 stx1Aa Shiga toxin Stx1a subunit A Protein Added: CAA85368.1 stx1Aa Shiga toxin Stx1a subunit A Protein Added: CAA85370.1 stx1Ac Shiga toxin Stx1c subunit A Protein Added: CAA85371.1 stx1Bc Shiga toxin Stx1c subunit B Protein Added: EQX61716.1 aggA aggregative adherence fimbria I major subunit AggA Protein Added: AAU95470.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: AAU95768.1 mepA multidrug efflux MATE transporter MepA Protein Added: CAG17536.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: CAG17541.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: AAD43578.1 astA heat-stable enterotoxin EAST1 Protein Added: AAD43579.1 astA heat-stable enterotoxin EAST1 Protein Added: CAA85780.1 stx2Aa Shiga toxin Stx2a subunit A Protein Added: AAA80193.1 mtrC multidrug efflux RND transporter periplasmic adaptor subunit MtrC Protein Added: AAD44693.1 mtrA efflux transporter MtrCDE transcriptional activator MtrA Protein Added: AAD47284.1 terZ tellurium resistance-associated protein TerZ Protein Added: AAW38464.1 lmrS multidrug efflux MFS transporter LmrS Protein Added: CAI43856.1 espF type III secretion system LEE effector EspF Protein Added: CAI43860.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: CAI43862.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAI43865.1 eae intimin type epsilon Protein Added: CAI43867.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAD54074.1 farB fatty acid resistance MFS efflux transporter permease subunit FarB Protein Added: BAA84838.1 bfpA bundle-forming pilus major subunit BfpA Protein Added: BAA84859.1 perA BFP system transcriptional regulator PerA Protein Added: AAT35241.2 tsh temperature-sensitive protease autotransporter hemagglutinin Tsh Protein Added: AAF03351.1 espF type III secretion system LEE effector EspF Protein Added: AHW84565.1 aaiC type VI secretion system protein AaiC/Hcp2 Protein Added: AHW84567.1 aaiC type VI secretion system protein AaiC/Hcp2 Protein Added: AAX47728.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAX47729.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAX47730.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAX47731.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: CAA58525.1 pcoA multicopper oxidase PcoA Protein Added: CAA58526.1 pcoB copper-binding protein PcoB Protein Added: CAA58527.1 pcoC copper resistance system metallochaperone PcoC Protein Added: CAA58528.1 pcoD copper resistance inner membrane protein PcoD Protein Added: CAA58529.1 pcoR copper response regulator transcription factor PcoR Protein Added: CAA58530.1 pcoS copper resistance membrane spanning protein PcoS Protein Added: CAA58532.1 pcoE copper resistance system metallochaperone PcoE Protein Added: AAX63244.1 fedF F18 fimbrial adhesin subunit FedF Protein Added: AAX63245.1 fedF F18 fimbrial adhesin subunit FedF Protein Added: AAX63259.1 fedF F18 fimbrial adhesin subunit FedF Protein Added: AAX63270.1 fedF F18 fimbrial adhesin subunit FedF Protein Added: AAY25390.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAY25394.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAY25395.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAF14522.1 mexX multidrug efflux RND transporter periplasmic adaptor subunit MexX Protein Added: CAI91198.1 stx2Ag Shiga toxin Stx2g subunit A Protein Added: AAF16681.1 srpS solvent efflux transporter transcriptional repressor SrpS Protein Added: AAF16682.1 srpR solvent efflux transporter antirepressor SrpR Protein Added: CAA54115.1 nfaE Dr family non-fimbrial adhesin I chaperone NfaE Protein Added: AAF23359.1 eae intimin type epsilon Protein Added: CAB64953.1 stx2Af Shiga toxin Stx2f subunit A Protein Added: AAY63864.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAY63865.1 stx2Bd Shiga toxin Stx2d subunit B Protein Added: CDY80020.1 hsp20 small heat shock protein sHSP20 Protein Added: AAY90615.1 emhC efflux RND transporter outer membrane subunit EmhC Protein Added: KGL71342.1 silF Ag(+)/Cu(+) efflux RND transporter periplasmic metallochaperone SilF Protein Added: AAF40764.1 farB fatty acid resistance MFS efflux transporter permease subunit FarB Protein Added: AAF42063.1 mtrC multidrug efflux RND transporter periplasmic adaptor subunit MtrC Protein Added: AAB26855.2 nfaE Dr family non-fimbrial adhesin I chaperone NfaE Protein Added: CAB82448.1 cnrY nickel resistance system anti-sigma factor CnrY Protein Added: AAZ76497.1 ehxA enterohemolysin Protein Added: AAZ76514.1 espP serine protease autotransporter EspP Protein Added: AAZ76524.1 subA subtilase AB5 cytotoxin subunit A Protein Added: AAZ87985.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: AAZ88030.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 Protein Added: AAZ89804.1 sigA serine protease autotransporter toxin SigA Protein Added: AAZ91108.1 ipaD type III secretion system needle tip complex protein IpaD Protein Added: ABA25986.1 merF mercury resistance system transport protein MerF Protein Added: AAX22079.2 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: AAA65102.1 nccX periplasmic metal sensor NccX Protein Added: AAA65103.1 nccH nickel/cobalt/cadmium resistance ECF sigma factor NccH Protein Added: ABB16332.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: ABB36584.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: ABB36586.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: ABB61187.1 iroN siderophore salmochelin receptor IroN Protein Added: ABB62096.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: ABB62098.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: ABB64677.1 ipaD type III secretion system needle tip complex protein IpaD Protein Added: ABB65884.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 Protein Added: ABB66229.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: ABB68924.1 virF AraC family invasion system transcriptional regulator VirF Protein Added: KLB41245.1 copL transcriptional regulator CopL Protein Added: CAI79539.1 eatA serine protease autotransporter toxin EatA Protein Added: CAJ44959.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: CAB77169.2 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAB94149.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: AAC34727.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: BAA96815.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAA69514.1 f17g F17G fimbrial adhesin Protein Added: CAA88252.1 sepA serine protease autotransporter toxin SepA Protein Added: BAE79899.1 smfY multidrug efflux MFS transporter SmfY Protein Added: ABE06598.1 sfaS S-fimbrial adhesin minor subunit SfaS Protein Added: ABE10324.1 cnf1 cytotoxic necrotizing factor CNF1 Protein Added: CAJ34994.1 bfpA bundle-forming pilus major subunit BfpA Protein Added: ABF13034.1 merD mercury resistance co-regulator MerD Protein Added: ABF13067.1 cnrC nickel efflux RND transporter outer membrane subunit CnrC Protein Added: ABF13069.1 cnrA nickel efflux RND transporter permease subunit CnrA Protein Added: ABF13070.1 cnrT nickel diffusion facilitator CnrT Protein Added: ABF14406.1 ncrA Metal Resistance Protein Added: ABF14407.1 ncrB nickel-sensing transcriptional repressor NcrB Protein Added: CAK02719.1 cnf1 cytotoxic necrotizing factor CNF1 Protein Added: CAA90630.1 stx2Aa Shiga toxin Stx2a subunit A Protein Added: BAT41861.1 eae intimin type alpha Protein Added: CAK15125.1 mexE MexE family multidrug efflux RND transporter periplasmic adaptor subunit Protein Added: AAG01033.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAB59153.1 cadC Cd(II)/Pb(II)/Zn(II)-sensing metalloregulatory transcriptional repressor CadC Protein Added: ABF61434.1 ncrA Metal Resistance Protein Added: ABF61435.1 ncrB nickel-sensing transcriptional repressor NcrB Protein Added: ABF61437.1 ncrY nickel resistance OB fold protein NcrY Protein Added: AAG05881.1 mexE MexE family multidrug efflux RND transporter periplasmic adaptor subunit Protein Added: AAG10695.1 perA BFP system transcriptional regulator PerA Protein Added: WP_000697899.1 pmrA pmrA Protein Added: WP_097509477.1 acrB acrB - AMRFinder HMM library Changes: Prev. Release: 574 This Release: 610 Removed: 2 Added: 38 Changed: 572 HMM Removed: NF000478.2 linco_LnuE HMM Removed: NF012180.1 tet_MFS_43 HMM Added: NF000131.1 MATE_multi_MepA HMM Added: NF000249.1 MexE HMM Added: NF000252.1 MexX HMM Added: NF000263.1 MATE_multi_NorM HMM Added: NF000282.2 RND_permease_1 HMM Added: NF000314.1 adeB HMM Added: NF000315.1 adeC-adeK-oprM HMM Added: NF000336.1 emrE HMM Added: NF007842.1 PRK10555.1 HMM Added: NF010310.2 PRK13747.1 HMM Added: NF010315.0 PRK13752.1 HMM Added: NF011706.2 PRK15127.1 HMM Added: NF028537.1 P_eth_NH2_trans HMM Added: NF033086.2 penta_rpt_Qnr HMM Added: NF033134.0 cmlA_floR HMM Added: NF033142.1 efflux_OM_AdeC HMM Added: NF033143.1 efflux_OM_AdeK HMM Added: NF033555.1 lyase_MerB HMM Added: NF033560.1 merT_RC607 HMM Added: NF033565.0 trans_MerF HMM Added: NF033627.3 intimin_all HMM Added: NF033637.1 transloc_TIR HMM Added: NF033639.1 intimin_alpha HMM Added: NF033643.1 EspJ_gen HMM Added: NF033646.1 toxin_EAST1 HMM Added: NF033651.1 cyto_nec_fctrs HMM Added: NF033658.1 Shiga_Stx1A HMM Added: NF033659.0 Shiga_Stx1B HMM Added: NF033660.0 Shiga_Stx2B HMM Added: NF033661.1 Shiga_Stx2A HMM Added: NF033727.1 chaperon_ArsD HMM Added: NF033781.1 chaper_CopP HMM Added: NF033783.1 coreg_MerD HMM Added: NF033784.1 transport_merC HMM Added: NF033786.1 phenyl_MerG HMM Added: NF033834.1 RND_adapt_MexA HMM Added: TIGR02052.1 TIGR02052 HMM Added: TIGR02053.1 TIGR02053 --------------------------------------------------------------------- Changes included in 2019-04-29.1 --------------------------------------------------------------------- Summary: In addition to the usual addition of 134 new genes and alleles community feedback led to the renaming of a few dfr genes. The family heirarchy file (fam.tab) was cleaned up by removing a number of superfluous entries. Changes included in 2019-04-29.1 - Protein changes: Prev. Release: 4810 This Release: 4942 Removed: 1 Added: 134 Modified: 3 Protein Removed: WP_109545040.1 chrB Protein Added: WP_000054744.1 satA_Ba Protein Added: WP_001211209.1 blaADC-140 Protein Added: WP_001211210.1 blaADC-185 Protein Added: WP_001211214.1 blaADC-144 Protein Added: WP_001211215.1 blaADC-115 Protein Added: WP_001572373.1 mcr-9.1 Protein Added: WP_002126587.1 blaADC-120 Protein Added: WP_002157727.1 blaADC-117 Protein Added: WP_003112187.1 blaADC-191 Protein Added: WP_003242546.1 satA_Bs Protein Added: WP_004643536.1 blaADC-128 Protein Added: WP_004700205.1 blaADC-133 Protein Added: WP_004707701.1 blaADC-131 Protein Added: WP_004712857.1 blaADC-119 Protein Added: WP_004790939.1 blaADC-135 Protein Added: WP_004840559.1 blaADC-123 Protein Added: WP_004886093.1 blaADC-130 Protein Added: WP_005039111.1 blaADC-129 Protein Added: WP_005046018.1 blaADC-127 Protein Added: WP_005068074.1 blaADC-132 Protein Added: WP_005109685.1 blaADC-121 Protein Added: WP_005123276.1 blaADC-122 Protein Added: WP_005131186.1 blaADC-125 Protein Added: WP_005307218.1 blaADC-134 Protein Added: WP_005404206.1 blaOXA-813 Protein Added: WP_005405613.1 blaOXA-814 Protein Added: WP_013197184.1 blaADC-193 Protein Added: WP_014207272.1 blaADC-149 Protein Added: WP_016137488.1 blaADC-136 Protein Added: WP_016140427.1 blaADC-137 Protein Added: WP_016146025.1 blaADC-138 Protein Added: WP_017386568.1 blaADC-150 Protein Added: WP_017778762.1 mcr-3.27 Protein Added: WP_017816757.1 blaADC-116 Protein Added: WP_026382828.1 blaOXA-114i Protein Added: WP_026444036.1 blaOXA-816 Protein Added: WP_032039838.1 blaADC-139 Protein Added: WP_032053762.1 blaOXA-819 Protein Added: WP_032057042.1 blaOXA-820 Protein Added: WP_032062810.1 blaADC-141 Protein Added: WP_032625176.1 blaACT-66 Protein Added: WP_033502167.1 blaADC-143 Protein Added: WP_034670108.1 blaOXA-818 Protein Added: WP_034688190.1 blaOXA-812 Protein Added: WP_036299413.1 sulR Protein Added: WP_039246976.1 blaADC-148 Protein Added: WP_039258389.1 blaADC-146 Protein Added: WP_039270258.1 blaADC-145 Protein Added: WP_044718369.1 blaADC-147 Protein Added: WP_047726486.1 blaACT-65 Protein Added: WP_053498400.1 blaOXA-114h Protein Added: WP_054437016.1 blaOXA-114j Protein Added: WP_054471662.1 blaOXA-114m Protein Added: WP_054500785.1 blaOXA-789 Protein Added: WP_054517040.1 blaOXA-114l Protein Added: WP_057061999.1 blaOXA-821 Protein Added: WP_059247009.1 blaADC-184 Protein Added: WP_063099318.1 blaADC-151 Protein Added: WP_063147148.1 blaACT-67 Protein Added: WP_072292271.1 blaADC-186 Protein Added: WP_075040046.1 blaOXA-817 Protein Added: WP_076412384.1 blaOXA-114p Protein Added: WP_099595307.1 dfrA35 Protein Added: WP_103663397.1 sulX Protein Added: WP_106743337.1 mcr-1.18 Protein Added: WP_109545052.1 mcr-1.14 Protein Added: WP_110612827.1 blaOXA-796 Protein Added: WP_111280830.1 blaOXA-815 Protein Added: WP_115470049.1 blaKPC-40 Protein Added: WP_117664257.1 cfxA6 Protein Added: WP_125052776.1 blaADC-114 Protein Added: WP_136512051.1 blaACT-68 Protein Added: WP_136512052.1 blaADC-109 Protein Added: WP_136512053.1 blaADC-110 Protein Added: WP_136512054.1 blaADC-112 Protein Added: WP_136512055.1 blaADC-113 Protein Added: WP_136512056.1 blaADC-187 Protein Added: WP_136512057.1 blaADC-188 Protein Added: WP_136512058.1 blaADC-189 Protein Added: WP_136512059.1 blaADC-190 Protein Added: WP_136512060.1 blaADC-192 Protein Added: WP_136512061.1 blaADC-24 Protein Added: WP_136512062.1 blaADC-65 Protein Added: WP_136512063.1 blaADC-66 Protein Added: WP_136512064.1 blaCTX-M-225 Protein Added: WP_136512065.1 blaCTX-M-226 Protein Added: WP_136512066.1 blaFRI-7 Protein Added: WP_136512067.1 blaIMI-18 Protein Added: WP_136512068.1 blaIMP-39 Protein Added: WP_136512069.1 blaIMP-46 Protein Added: WP_136512070.1 blaKPC-42 Protein Added: WP_136512071.1 blaKPC-43 Protein Added: WP_136512072.1 blaNDM-28 Protein Added: WP_136512073.1 blaOXA-114k Protein Added: WP_136512074.1 blaOXA-114n Protein Added: WP_136512075.1 blaOXA-114q Protein Added: WP_136512076.1 blaOXA-114r Protein Added: WP_136512077.1 blaOXA-114s Protein Added: WP_136512078.1 blaOXA-114t Protein Added: WP_136512079.1 blaOXA-114u Protein Added: WP_136512080.1 blaOXA-114v Protein Added: WP_136512081.1 blaOXA-114w Protein Added: WP_136512082.1 blaOXA-114x Protein Added: WP_136512083.1 blaOXA-787 Protein Added: WP_136512084.1 blaOXA-788 Protein Added: WP_136512085.1 blaOXA-793 Protein Added: WP_136512086.1 blaOXA-794 Protein Added: WP_136512087.1 blaOXA-795 Protein Added: WP_136512088.1 blaOXA-797 Protein Added: WP_136512089.1 blaOXA-798 Protein Added: WP_136512090.1 blaOXA-799 Protein Added: WP_136512091.1 blaOXA-800 Protein Added: WP_136512092.1 blaOXA-801 Protein Added: WP_136512093.1 blaOXA-802 Protein Added: WP_136512094.1 blaOXA-803 Protein Added: WP_136512095.1 blaOXA-804 Protein Added: WP_136512096.1 blaOXA-805 Protein Added: WP_136512097.1 blaOXA-806 Protein Added: WP_136512098.1 blaOXA-807 Protein Added: WP_136512099.1 blaOXA-808 Protein Added: WP_136512100.1 blaOXA-809 Protein Added: WP_136512101.1 blaOXA-810 Protein Added: WP_136512102.1 blaOXA-811 Protein Added: WP_136512103.1 blaOXA-823 Protein Added: WP_136512104.1 blaOXA-824 Protein Added: WP_136512105.1 blaPER-13 Protein Added: WP_136512106.1 blaVIM-48 Protein Added: WP_136512107.1 blaVIM-55 Protein Added: WP_136512108.1 blaVIM-63 Protein Added: WP_136512109.1 blaVIM-66 Protein Added: WP_136512110.1 mcr-1.16 Protein Added: WP_136512111.1 mcr-1.17 Protein Added: WP_136512112.1 mcr-3.29 Protein Modified: WP_001031075.1 dfr18 updated to WP_001031075.1 dfrA18 Protein Modified: WP_032490189.1 dfrA18 updated to WP_032490189.1 dfrA19 Protein Modified: WP_063843245.1 chrB updated to WP_063843245.1 chrB_rRNA_meth - AMR HMM library Changes: Prev. Release: 571 This Release: 574 Removed: 0 Added: 3 Changed: 571 HMM Added: NF033818.0 blaOXA-114_like HMM Added: NF033836.1 polymyxin_MCR9 HMM Added: NF033851.1 trim_DfrA35 HMM Modified: NF000039.1 trim_Dfr18 renamed to NF000039.1 trim_DfrA18 HMM Modified: NF000041.1 trim_DfrA18_A19 renamed to NF000041.1 trim_DfrA19 HMM Modified: NF000422.2 blaPDC updated to NF000422.6 blaPDC - Protein family changes: Prev. Release: 1177 This Release: 1119 Removed: 68 Added: 10 Modified: 4 Family Removed: - PORIN Family Removed: - aac(1) Family Removed: - aac(3')-IIe Family Removed: - aac(3)-Ie Family Removed: - aac(3)-VI Family Removed: - aac(3)-Vb Family Removed: - aac(6')-Ib8 Family Removed: - aacA44 Family Removed: - aadA1bt Family Removed: - aadA1r Family Removed: - aadA24 Family Removed: - ampC_Eae Family Removed: - ampH Family Removed: - ampS Family Removed: - ant(3'')(9) Family Removed: - ant(3'')-Ii Family Removed: - aph(3')-Ic Family Removed: - arr-Cb Family Removed: - blaCMG Family Removed: - blaKLUG Family Removed: - blaLMB Family Removed: - blaMSI-OXA Family Removed: - blaOXA_missing Family Removed: - blaPNGM Family Removed: - blaZEG Family Removed: - blmS Family Removed: - catA12 Family Removed: - ccrA Family Removed: NF000488.1 chrB Family Removed: - cml Family Removed: - cmlA7 Family Removed: - cmlA9 Family Removed: NF000039.1 dfr18 Family Removed: NF000041.1 dfrA18_dfrA19 Family Removed: - dfrA1_var Family Removed: - dfrA29 Family Removed: - dfrA33 Family Removed: - dfrB7 Family Removed: - flo Family Removed: - mef(E) Family Removed: - mef(G) Family Removed: - mef(I) Family Removed: - mph(D) Family Removed: - nimF Family Removed: - nimH Family Removed: - omp35 Family Removed: - ompE35 Family Removed: - otr(C) Family Removed: - penA Family Removed: - sat2A Family Removed: - sat3A Family Removed: - spc Family Removed: - sul1delta Family Removed: - vanH-Ac2 Family Removed: - vanH-F Family Removed: - vanR-Pt Family Removed: - vanR-Pt2 Family Removed: - vanS-I Family Removed: - vanSc Family Removed: - vanTc4 Family Removed: - vanX-Ac2 Family Removed: - vanX-F Family Removed: - vanX-Pt2 Family Removed: - vanY-40021673 Family Removed: - vanY-D4 Family Removed: - vanY-D5 Family Removed: - vanY-M Family Removed: - vanY-Pt2 Family Added: NF033818.0 blaOXA-114_like Family Added: NF033851.1 dfrA35 Family Added: NF033124.1 estX Family Added: NF033836.1 mcr-9 Family Added: - satA_Bs Family Added: - sulR Family Added: - sulX Family Changed: NF000422.2 blaPDC updated to NF000422.6 blaPDC Family Changed: NF000488.1 chrB renamed to chrB_rRNA_meth Family Changed: NF000039.1 dfr18 renamed to dfrA18 Family Changed: NF000041.1 dfrA18_dfrA19 renamed to dfrA19 --------------------------------------------------------------------- Changes included in 2019-02-08.1 --------------------------------------------------------------------- Two incorrectly assigned proteins were accidentally released. They are not AMR proteins and should not have been released. This release simply removes them and is otherwise unchanged. - Protein changes: Prev. Release: 4812 This Release: 4810 Removed: 2 Added: 0 Changed: 4810 Protein Removed: WP_000122253.1 sat Protein Removed: WP_001045652.1 sat --------------------------------------------------------------------- Changes included in 2019-02-04.1 --------------------------------------------------------------------- - Protein name changes: "inhibitor-resistant" was added to the names of: blaKPC-8 blaKPC-30 blaKPC-31 blaKPC-32 blaKPC-33 - Protein changes: Prev. Release: 4730 This Release: 4812 Removed: 0 Added: 82 Protein modified: WP_063855700.1 tet(35) replaced with WP_005480402.1 Protein Added: WP_000122253.1 sat Protein Added: WP_001045652.1 sat Protein Added: WP_002415638.1 poxtA Protein Added: WP_003234144.1 vmlR Protein Added: WP_029728367.1 blaB Protein Added: WP_044103626.1 blaVEB-21 Protein Added: WP_046693238.1 blaADC-181 Protein Added: WP_049637206.1 blaOXA-780 Protein Added: WP_057691114.1 blaADC-182 Protein Added: WP_058492019.1 vanI Protein Added: WP_065980086.1 blaOXA-784 Protein Added: WP_069953510.1 blaAFM-1 Protein Added: WP_069996660.1 mecC3 Protein Added: WP_071223118.1 taeA Protein Added: WP_087343787.1 ant(6)-Ic Protein Added: WP_087344360.1 blaBBI Protein Added: WP_087344902.1 catV Protein Added: WP_087346196.1 ant(4')-Ic Protein Added: WP_087347987.1 rphC Protein Added: WP_087348261.1 rphD Protein Added: WP_087349244.1 mphJ Protein Added: WP_087349651.1 aac(6')-35 Protein Added: WP_114225343.1 blaOXA-739 Protein Added: WP_123002100.1 blaGES-40 Protein Added: WP_123002101.1 blaKPC-38 Protein Added: WP_123002102.1 blaNDM-27 Protein Added: WP_123002103.1 blaVIM-61 Protein Added: WP_126205827.1 blaOXA-785 Protein Added: WP_127728991.1 blaFRI-6 Protein Added: WP_128268231.1 mecC2 Protein Added: WP_128268232.1 blaADC-183 Protein Added: WP_128268233.1 blaCARB-50 Protein Added: WP_128268234.1 blaCFE-2 Protein Added: WP_128268235.1 blaCTX-M-215 Protein Added: WP_128268236.1 blaDHA-28 Protein Added: WP_128268237.1 blaKPC-39 Protein Added: WP_128268238.1 blaOXA-738 Protein Added: WP_128268239.1 blaOXA-740 Protein Added: WP_128268240.1 blaOXA-741 Protein Added: WP_128268241.1 blaOXA-742 Protein Added: WP_128268242.1 blaOXA-743 Protein Added: WP_128268243.1 blaOXA-744 Protein Added: WP_128268244.1 blaOXA-745 Protein Added: WP_128268245.1 blaOXA-746 Protein Added: WP_128268246.1 blaOXA-747 Protein Added: WP_128268247.1 blaOXA-748 Protein Added: WP_128268248.1 blaOXA-749 Protein Added: WP_128268249.1 blaOXA-750 Protein Added: WP_128268250.1 blaOXA-751 Protein Added: WP_128268251.1 blaOXA-752 Protein Added: WP_128268252.1 blaOXA-753 Protein Added: WP_128268253.1 blaOXA-754 Protein Added: WP_128268254.1 blaOXA-755 Protein Added: WP_128268255.1 blaOXA-756 Protein Added: WP_128268256.1 blaOXA-757 Protein Added: WP_128268257.1 blaOXA-758 Protein Added: WP_128268258.1 blaOXA-759 Protein Added: WP_128268259.1 blaOXA-760 Protein Added: WP_128268260.1 blaOXA-761 Protein Added: WP_128268261.1 blaOXA-762 Protein Added: WP_128268262.1 blaOXA-763 Protein Added: WP_128268263.1 blaOXA-764 Protein Added: WP_128268264.1 blaOXA-765 Protein Added: WP_128268265.1 blaOXA-766 Protein Added: WP_128268266.1 blaOXA-767 Protein Added: WP_128268267.1 blaOXA-768 Protein Added: WP_128268268.1 blaOXA-769 Protein Added: WP_128268269.1 blaOXA-770 Protein Added: WP_128268270.1 blaOXA-771 Protein Added: WP_128268271.1 blaOXA-772 Protein Added: WP_128268272.1 blaOXA-773 Protein Added: WP_128268273.1 blaOXA-774 Protein Added: WP_128268274.1 blaOXA-775 Protein Added: WP_128268275.1 blaOXA-776 Protein Added: WP_128268276.1 blaOXA-781 Protein Added: WP_128268277.1 blaOXA-782 Protein Added: WP_128268278.1 blaOXA-783 Protein Added: WP_128268279.1 blaOXA-786 Protein Added: WP_128268280.1 blaPDC-317 Protein Added: WP_128268286.1 blaVEB-20 Protein Added: WP_128268287.1 blaVIM-62 Protein Added: WP_128268288.1 qnrS15 - AMR HMM library Changes: Prev. Release: 568 This Release: 571 Removed: 0 Added: 3 HMM Added: NF033714.1 blaBBI HMM Added: NF033736.1 blaAFM HMM Added: NF033815.0 blaOXA-364_like HMM Modified: NF000355.2 ribo_prot_ABC_F updated to NF000355.3 ribo_prot_ABC_F - Protein family changes: Prev. Release: 1161 This Release: 1177 Removed: 0 Added: 16 Family Added: - aac(6')-35 Family Added: - ant(4')-Ic Family Added: - ant(6)-Ic Family Added: NF033736.1 blaAFM Family Added: NF033714.1 blaBBI Family Added: NF033815.0 blaOXA-364_like Family Added: - mecC2 Family Added: - mecC3 Family Added: - mphJ Family Added: - poxtA Family Added: - rphC Family Added: - rphD Family Added: - rph_gen Family Added: - satA_Ba Family Added: - taeA Family Added: - vmlR Family Changed: NF000355.2 abc-f updated to NF000355.3 abc-f --------------------------------------------------------------------- Changes included in 2018-11-07.1 --------------------------------------------------------------------- Due to a communication error three blaOXA alleles in the AMR database have been reassigned. Alleles published by Tian, et al. (PMID:30247543) have replaced them. AFY12006.1 JX846494.1 WP_072678505.1 NG_061615.1 were blaOXA-669, now they are blaOXA-732 AAL47570.1 AY066004.1 WP_114699266.1 NG_061383.1 were blaOXA-666, now they are blaOXA-729 AXH06203.1 MH684781.1 WP_116786836.1 NG_061623.1 were blaOXA-667, now they are blaOXA-730 - Protein changes: Prev. Release: 4579 This Release: 4730 Removed: 0 Added: 151 Protein Added: WP_004143591.1 blaSHV-206 Protein Added: WP_004384957.1 blaCSA-2 Protein Added: WP_007888761.1 blaCSA-1 Protein Added: WP_011245929.1 clbB Protein Added: WP_011707905.1 blaOXA-725 Protein Added: WP_012116915.1 clbA Protein Added: WP_015892743.1 clbC Protein Added: WP_016162389.1 blaOXA-673 Protein Added: WP_016168805.1 blaOXA-664 Protein Added: WP_016651348.1 blaOXA-670 Protein Added: WP_016657654.1 blaOXA-665 Protein Added: WP_016660101.1 blaOXA-671 Protein Added: WP_016685888.1 blaOXA-715 Protein Added: WP_017822040.1 qnrVC10 Protein Added: WP_023271137.1 blaOXA-672 Protein Added: WP_023341517.1 blaSHV-211 Protein Added: WP_031998610.1 blaOXA-716 Protein Added: WP_032018141.1 blaOXA-717 Protein Added: WP_032495491.1 blaKLUC-3 Protein Added: WP_032495492.1 blaKLUC-4 Protein Added: WP_032974004.1 blaCMA-1 Protein Added: WP_033179079.1 crpP Protein Added: WP_034612711.1 blaOXA-668 Protein Added: WP_056517622.1 blaOXA-669 Protein Added: WP_057097547.1 aph(2'')-If2 Protein Added: WP_058652112.1 dfrA34 Protein Added: WP_064733493.1 blaSHV-207 Protein Added: WP_064760451.1 qepA4 Protein Added: WP_064768701.1 qepA7 Protein Added: WP_077096319.1 blaOXA-724 Protein Added: WP_081406929.1 blaOXA-674 Protein Added: WP_081853183.1 blaELM-1 Protein Added: WP_092689909.1 blaOXA-666 Protein Added: WP_094166899.1 blaCTX-M-224 Protein Added: WP_096735335.1 blaOXA-667 Protein Added: WP_096941464.1 qepA6 Protein Added: WP_100663667.1 blaKLUC-5 Protein Added: WP_101150415.1 blaOXA-726 Protein Added: WP_104159136.1 blaSHV-224 Protein Added: WP_105620838.1 blaCMA-2 Protein Added: WP_109232473.1 blaSHV-220 Protein Added: WP_109638756.1 qepA8 Protein Added: WP_112021705.1 qepA9 Protein Added: WP_113334341.1 qepA10 Protein Added: WP_115196748.1 blaSHV-210 Protein Added: WP_117241614.1 blaSHV-223 Protein Added: WP_122630822.1 blaEFM-1 Protein Added: WP_122630823.1 blaEVM-1 Protein Added: WP_122630824.1 blaECM-1 Protein Added: WP_122630825.1 blaEAM-1 Protein Added: WP_122630826.1 blaGES-38 Protein Added: WP_122630827.1 blaGES-39 Protein Added: WP_122630828.1 blaVIM-53 Protein Added: WP_122630829.1 blaDHT2-1 Protein Added: WP_122630830.1 blaSPN79-1 Protein Added: WP_122630831.1 blaCRD3-1 Protein Added: WP_122630832.1 blaALG6-1 Protein Added: WP_122630833.1 blaALG11-1 Protein Added: WP_122630834.1 blaGRD33-1 Protein Added: WP_122630835.1 blaGRD23-1 Protein Added: WP_122630836.1 blaCMY-158 Protein Added: WP_122630837.1 blaCMY-159 Protein Added: WP_122630838.1 blaSHV-201 Protein Added: WP_122630839.1 blaSHV-202 Protein Added: WP_122630840.1 aph(2'') Protein Added: WP_122630841.1 blaTEM-237 Protein Added: WP_122630842.1 blaOXA-655 Protein Added: WP_122630843.1 blaOXA-656 Protein Added: WP_122630844.1 blaOXA-733 Protein Added: WP_122630845.1 blaPDC-307 Protein Added: WP_122630846.1 blaPDC-308 Protein Added: WP_122630847.1 blaPDC-309 Protein Added: WP_122630848.1 blaPDC-310 Protein Added: WP_122630849.1 blaPDC-311 Protein Added: WP_122630850.1 blaPDC-312 Protein Added: WP_122630851.1 blaPDC-313 Protein Added: WP_122630852.1 blaPDC-314 Protein Added: WP_122630853.1 blaOXA-734 Protein Added: WP_122630854.1 blaOXA-735 Protein Added: WP_122630855.1 blaOXA-736 Protein Added: WP_122630856.1 blaOXA-737 Protein Added: WP_122630857.1 blaOXA-675 Protein Added: WP_122630858.1 blaOXA-676 Protein Added: WP_122630859.1 blaOXA-677 Protein Added: WP_122630860.1 blaOXA-678 Protein Added: WP_122630861.1 blaIMP-80 Protein Added: WP_122630862.1 blaCTX-M-223 Protein Added: WP_122630863.1 blaSHV-205 Protein Added: WP_122630864.1 blaOXA-680 Protein Added: WP_122630865.1 blaSHV-208 Protein Added: WP_122630866.1 blaSHV-209 Protein Added: WP_122630867.1 blaSHV-212 Protein Added: WP_122630868.1 blaSHV-213 Protein Added: WP_122630869.1 blaSHV-214 Protein Added: WP_122630870.1 blaSHV-215 Protein Added: WP_122630871.1 blaSHV-216 Protein Added: WP_122630872.1 blaSHV-217 Protein Added: WP_122630873.1 blaSHV-218 Protein Added: WP_122630874.1 blaSHV-219 Protein Added: WP_122630875.1 blaSHV-221 Protein Added: WP_122630876.1 blaSHV-222 Protein Added: WP_122630877.1 blaSHV-225 Protein Added: WP_122630878.1 blaSHV-226 Protein Added: WP_122630879.1 blaSHV-227 Protein Added: WP_122630880.1 blaSHV-228 Protein Added: WP_122630881.1 blaOXA-681 Protein Added: WP_122630882.1 blaPDC-315 Protein Added: WP_122630883.1 blaPDC-316 Protein Added: WP_122630884.1 blaOXA-682 Protein Added: WP_122630885.1 blaOXA-683 Protein Added: WP_122630886.1 blaOXA-684 Protein Added: WP_122630887.1 blaOXA-685 Protein Added: WP_122630888.1 blaOXA-686 Protein Added: WP_122630889.1 blaOXA-687 Protein Added: WP_122630890.1 blaOXA-688 Protein Added: WP_122630891.1 blaOXA-689 Protein Added: WP_122630892.1 blaOXA-690 Protein Added: WP_122630893.1 blaOXA-691 Protein Added: WP_122630894.1 blaOXA-692 Protein Added: WP_122630895.1 blaOXA-693 Protein Added: WP_122630896.1 blaOXA-694 Protein Added: WP_122630897.1 blaOXA-695 Protein Added: WP_122630898.1 blaOXA-696 Protein Added: WP_122630899.1 blaOXA-697 Protein Added: WP_122630900.1 blaOXA-698 Protein Added: WP_122630901.1 blaOXA-699 Protein Added: WP_122630902.1 blaOXA-700 Protein Added: WP_122630903.1 blaOXA-701 Protein Added: WP_122630904.1 blaOXA-702 Protein Added: WP_122630905.1 blaOXA-703 Protein Added: WP_122630906.1 blaOXA-704 Protein Added: WP_122630907.1 blaOXA-705 Protein Added: WP_122630908.1 blaOXA-706 Protein Added: WP_122630909.1 blaOXA-707 Protein Added: WP_122630910.1 blaOXA-718 Protein Added: WP_122630911.1 blaOXA-719 Protein Added: WP_122630912.1 blaOXA-720 Protein Added: WP_122630913.1 blaOXA-721 Protein Added: WP_122630914.1 blaOXA-722 Protein Added: WP_122630915.1 blaOXA-723 Protein Added: WP_122630916.1 blaOXA-708 Protein Added: WP_122630917.1 blaOXA-709 Protein Added: WP_122630918.1 blaOXA-710 Protein Added: WP_122630919.1 blaOXA-711 Protein Added: WP_122630920.1 blaOXA-712 Protein Added: WP_122630921.1 blaOXA-713 Protein Added: WP_122630922.1 blaOXA-714 Protein Added: WP_122630923.1 blaOXA-777 Protein Added: WP_122630924.1 blaOXA-778 Protein Added: WP_122634438.1 blaOXA-779 Protein Added: WP_122634439.1 blaOXA-679 Gene Symbol Modified: WP_010890145.1 qacE_gen updated to WP_010890145.1 qacE Gene Symbol Modified: WP_053515552.1 qacE_gen updated to WP_053515552.1 qacE Gene Symbol Modified: WP_063844281.1 cphA updated to WP_063844281.1 cphA3 Gene Symbol Modified: WP_063854778.1 qepA updated to WP_063854778.1 qepA5 Gene Symbol Modified: WP_072678505.1 blaOXA-669 updated to WP_072678505.1 blaOXA-732 Gene Symbol Modified: WP_114699266.1 blaOXA-666 updated to WP_114699266.1 blaOXA-729 Gene Symbol Modified: WP_116786836.1 blaOXA-667 updated to WP_116786836.1 blaOXA-730 - AMR HMM library Changes: Prev. Release: 563 This Release: 568 Removed: 0 Added: 5 HMM Added: NF033692.1 APH_2pp_I_a_f_h HMM Added: NF033693.0 AAC_6p_Ie_fam HMM Added: NF033698.1 blaCSA HMM Added: NF033700.1 blaCMA HMM Added: NF033702.0 blaOXA-12_like HMM Name Modified: NF033666.1 blaOXA-664_like updated to NF033666.1 blaOXA-727_like - Protein family changes: Prev. Release: 1133 This Release: 1161 Removed: 0 Added: 28 Family Added: - aac(6')-Ie2 Family Added: NF033693.0 aac(6')-Ie_fam Family Added: NF011706.2 acrB Family Added: NF007842.1 acrD Family Added: NF000314.1 adeB/adeJ Family Added: NF033692.1 aph(2'')-I_a_f_h Family Added: - aph(2'')-If2 Family Added: - blaALG11 Family Added: - blaALG6 Family Added: NF033700.1 blaCMA Family Added: - blaCRD3 Family Added: NF033698.1 blaCSA Family Added: - blaCrA Family Added: - blaDHT2 Family Added: - blaEAM Family Added: - blaECM Family Added: - blaEFM Family Added: - blaELM Family Added: - blaEVM Family Added: - blaGRD23 Family Added: - blaGRD33 Family Added: NF033702.0 blaOXA-12_like Family Added: - blaPNGM Family Added: - blaSPN79 Family Added: - catV Family Added: - crpP Family Added: - dfrA34 Family Added: - qacE Family Renamed: NF033666.1 blaOXA-664_like became blaOXA-727_like --------------------------------------------------------------------- Changes included in 2018-09-14.1 ---------------------------------------------------------------------- - Protein changes: Prev. Release: 4569 This Release: 4579 Removed: 0 Added: 10 Protein Added: WP_116786828.1 mcr-4.6 Protein Added: WP_116786829.1 blaCTX-M-222 Protein Added: WP_116786830.1 mcr-1.15 Protein Added: WP_116786831.1 blaTEM-236 Protein Added: WP_116786832.1 blaKPC-37 Protein Added: WP_116786834.1 blaPDC-304 Protein Added: WP_116786836.1 blaOXA-667 Protein Added: WP_116786837.1 blaPDC-305 Protein Added: WP_116786838.1 blaPDC-306 Protein Added: WP_116786839.1 blaIMP-79 - AMR HMM library Changes: Prev. Release: 563 This Release: 563 Removed: 0 Added: 0 - Protein family changes: Prev. Release: 1133 This Release: 1133 Removed: 0 Added: 0 --------------------------------------------------------------------- Changes included in 2018-08-24.1 --------------------------------------------------------------------- - Protein changes: Prev. Release: 4563 This Release: 4569 Removed: 1 Added: 7 Protein Removed: WP_063843217.1 catA1 Protein Added: WP_003436401.1 vanR-Cd Protein Added: WP_009889012.1 vanZ1 Protein Added: WP_011861275.1 vanS-Cd Protein Added: WP_011861276.1 vanG-Cd Protein Added: WP_020924773.1 blaAXC-1 Protein Added: WP_072310976.1 mcr-8.2 Protein Added: WP_072678505.1 blaOXA-669 - AMR HMM library Changes: Prev. Release: 563 This Release: 563 Removed: 0 Added: 0 - Protein family changes: Prev. Release: 1128 This Release: 1133 Removed: 0 Added: 5 Family Added: - blaAXC Family Added: - vanG-Cd Family Added: - vanR-Cd Family Added: - vanS-Cd Family Added: - vanZ1 --------------------------------------------------------------------- Changes included in 2018-08-01.1 --------------------------------------------------------------------- - Protein changes: Prev. Release: 4528 This Release: 4563 Removed: 0 Added: 35 Protein Added: WP_000622776.1 qacA Protein Added: WP_001159761.1 blaADC-176 Protein Added: WP_001211208.1 blaADC-175 Protein Added: WP_010730188.1 qacZ Protein Added: WP_013095270.1 blaCMH-4 Protein Added: WP_032410229.1 blaOXA-663 Protein Added: WP_033487869.1 blaACT-56 Protein Added: WP_046887417.1 blaCMH-5 Protein Added: WP_047052637.1 blaACT-55 Protein Added: WP_050861789.1 blaACT-64 Protein Added: WP_070210118.1 blaOXA-658 Protein Added: WP_094935119.1 blaACT-57 Protein Added: WP_111772163.1 blaVIM-58 Protein Added: WP_111976052.1 blaACT-60 Protein Added: WP_112017656.1 blaACT-61 Protein Added: WP_112792421.1 blaACT-59 Protein Added: WP_114699266.1 blaOXA-666 Protein Added: WP_114699267.1 blaKPC-36 Protein Added: WP_114699268.1 blaADC-174 Protein Added: WP_114699269.1 blaADC-177 Protein Added: WP_114699270.1 blaADC-178 Protein Added: WP_114699271.1 blaADC-179 Protein Added: WP_114699272.1 blaADC-180 Protein Added: WP_114699273.1 blaOXA-661 Protein Added: WP_114699274.1 blaOXA-662 Protein Added: WP_114699275.1 mcr-8.1 Protein Added: WP_114699276.1 blaOXA-659 Protein Added: WP_114699277.1 blaVIM-60 Protein Added: WP_114699278.1 mcr-5.3 Protein Added: WP_114699279.1 blaOXA-660 Protein Added: WP_114699280.1 blaIMP-76 Protein Added: WP_114699281.1 blaIMP-77 Protein Added: WP_114699282.1 blaIMP-78 Protein Added: WP_114699283.1 blaVIM-59 Protein Added: WP_114699284.1 blaCTX-M-221 - AMR HMM library Changes: Prev. Release: 557 This Release: 563 Removed: 0 Added: 6 HMM Added: NF033648.1 blaOXA-274_like HMM Added: NF033666.1 blaOXA-664_like HMM Added: NF033667.0 blaOXA-55_like HMM Added: NF033669.1 polymyxin_MCR8 HMM Added: NF033670.1 polymyxin_MCR6 HMM Added: NF033671.1 polymyxin_MCR7 - Protein family changes: Prev. Release: 1123 This Release: 1128 Removed: 0 Added: 5 Family Added: - blaOXA-266_fam Family Added: NF033648.1 blaOXA-274_like Family Added: NF033667.1 blaOXA-55_like Family Added: NF033666.1 blaOXA-664_like Family Added: NF033669.1 mcr-8 HMM Added: mcr-6 updated to NF033670.1 mcr-6 HMM Added: mcr-7 updated to NF033671.1 mcr-7 Updates in 2018-07-07.1 - Fix in amr_report.cpp to remove extra field from AMRFinder output Updates in 2018-06-27.1 - Summary: - Protein sequences - Removed 1 protein sequence - Added 290 protein sequences - Changed the names of 2 proteins - Gene families - cfr was reorganized - HMM library - 58 HMMs not in the AMR family hierarchy were removed. They were not used for AMR gene identification so this should have no effect on AMRFinder output. - The polymyxin_MCR3 HMM was updated - Details: Protein Removed: WP_063945333.1 aac(6')-IIa Protein Added: WP_000131886.1 aac(3)-VIa Protein Added: WP_000778180.1 varG Protein Added: WP_001100752.1 blaPER-10 Protein Added: WP_002812372.1 blaOXA-578 Protein Added: WP_002824679.1 blaOXA-595 Protein Added: WP_002837769.1 blaOXA-579 Protein Added: WP_002857546.1 blaOXA-592 Protein Added: WP_002889704.1 blaOXA-591 Protein Added: WP_002936877.1 blaOXA-623 Protein Added: WP_011339581.1 blaRHO Protein Added: WP_011497575.1 blaSHN-1 Protein Added: WP_011550565.1 blaMYX-1 Protein Added: WP_011638903.1 mcr-4.3 Protein Added: WP_012263521.1 mupA Protein Added: WP_012541790.1 blaLEN-28 Protein Added: WP_012698469.1 blaLHK-7 Protein Added: WP_013255389.1 blaSPS-1 Protein Added: WP_013992183.1 blaZOG-1 Protein Added: WP_014206564.1 blaOXA-642 Protein Added: WP_015058260.1 qnrS11 Protein Added: WP_015266427.1 blaECV-1 Protein Added: WP_015431537.1 blaROB-2 Protein Added: WP_015818996.1 blaTTU-1 Protein Added: WP_016252988.1 blaPDC-286 Protein Added: WP_021018581.1 catB8 Protein Added: WP_025006557.1 blaOXA-580 Protein Added: WP_026025287.1 blaALI-1 Protein Added: WP_031192893.1 aadA31 Protein Added: WP_034035338.1 blaPDC-240 Protein Added: WP_035203840.1 catA10 Protein Added: WP_038333643.1 blaEBR-2 Protein Added: WP_038640920.1 qnrB12 Protein Added: WP_041079981.1 erm(44)v Protein Added: WP_041258349.1 blaFIA-1 Protein Added: WP_041385949.1 blaSGM-2 Protein Added: WP_041449074.1 blaANA-1 Protein Added: WP_043774378.1 catA13 Protein Added: WP_043942497.1 blaPST-1 Protein Added: WP_044600959.1 blaOXA-594 Protein Added: WP_044779552.1 blaOXA-638 Protein Added: WP_048236419.1 qnrB85 Protein Added: WP_052259183.1 erm(42) Protein Added: WP_052781249.1 blaOXA-583 Protein Added: WP_052788483.1 blaOXA-611 Protein Added: WP_052788887.1 blaOXA-581 Protein Added: WP_052794776.1 blaOXA-625 Protein Added: WP_052798312.1 blaOXA-609 Protein Added: WP_052800105.1 blaOXA-597 Protein Added: WP_052803794.1 blaOXA-601 Protein Added: WP_052858477.1 blaOXA-637 Protein Added: WP_053872444.1 blaOXA-639 Protein Added: WP_053921012.1 blaOXA-603 Protein Added: WP_057036510.1 blaOXA-629 Protein Added: WP_058157026.1 blaPDC-271 Protein Added: WP_058174497.1 blaPDC-250 Protein Added: WP_058870660.1 blaOXA-651 Protein Added: WP_058951457.1 blaOXA-652 Protein Added: WP_061193431.1 blaPDC-298 Protein Added: WP_064186845.1 qnrS13 Protein Added: WP_065597326.1 blaALI-2 Protein Added: WP_065801616.1 mcr-3.20 Protein Added: WP_065908739.1 qnrB91 Protein Added: WP_070233680.1 blaOXA-614 Protein Added: WP_070698497.1 blaPDC-278 Protein Added: WP_071701819.1 qnrS12 Protein Added: WP_071846333.1 aac(6')_Serra Protein Added: WP_073669325.1 blaPDC-285 Protein Added: WP_075606311.1 blaROB-3 Protein Added: WP_078207746.1 qnrE2 Protein Added: WP_078318620.1 blaROB-4 Protein Added: WP_080699425.1 blaTEM-229 Protein Added: WP_081048762.1 blaMYO-1 Protein Added: WP_081666691.1 blaLHK-1 Protein Added: WP_085843691.1 qnrB95 Protein Added: WP_087696200.1 blaOXA-576 Protein Added: WP_087879616.1 mcr-3.19 Protein Added: WP_088303859.1 blaOXA-624 Protein Added: WP_094308975.1 mcr-3.22 Protein Added: WP_094312656.1 mcr-3.21 Protein Added: WP_094313523.1 mcr-3.23 Protein Added: WP_094321595.1 mcr-3.24 Protein Added: WP_094963248.1 aadA31 Protein Added: WP_096170112.1 qnrS14 Protein Added: WP_096865225.1 blaPER-12 Protein Added: WP_100831609.1 blaPDC-245 Protein Added: WP_103034696.1 blaROB-5 Protein Added: WP_103252528.1 mcr-3.25 Protein Added: WP_104009831.1 blaPER-11 Protein Added: WP_104009832.1 blaPDC-234 Protein Added: WP_104009833.1 blaPDC-235 Protein Added: WP_104009834.1 blaPDC-236 Protein Added: WP_104009835.1 blaPDC-237 Protein Added: WP_104009836.1 blaPDC-238 Protein Added: WP_104009837.1 blaPDC-239 Protein Added: WP_104009838.1 blaPDC-241 Protein Added: WP_104009839.1 blaPDC-242 Protein Added: WP_104009840.1 blaPDC-243 Protein Added: WP_104009841.1 blaPDC-244 Protein Added: WP_104009842.1 blaPDC-246 Protein Added: WP_104009843.1 blaPDC-247 Protein Added: WP_104009844.1 blaPDC-248 Protein Added: WP_104009846.1 blaVIM-56 Protein Added: WP_104009847.1 blaCTX-M-178 Protein Added: WP_104009848.1 blaCTX-M-187 Protein Added: WP_104009849.1 blaCMY-156 Protein Added: WP_104009850.1 mcr-1.12 Protein Added: WP_104009851.1 mcr-7.1 Protein Added: WP_104009852.1 blaIMP-71 Protein Added: WP_104009853.1 blaOXA-575 Protein Added: WP_104009854.1 blaTEM-230 Protein Added: WP_104009855.1 blaTEM-231 Protein Added: WP_104009856.1 blaPDC-227 Protein Added: WP_104009857.1 blaPDC-228 Protein Added: WP_104009858.1 blaPDC-229 Protein Added: WP_104009859.1 blaPDC-230 Protein Added: WP_104009860.1 blaPDC-231 Protein Added: WP_104009861.1 blaPDC-232 Protein Added: WP_104009862.1 blaPDC-233 Protein Added: WP_104531863.1 blaBUT-1 Protein Added: WP_104531864.1 blaBUT-2 Protein Added: WP_104531865.1 blaLHK-2 Protein Added: WP_104531866.1 blaLHK-3 Protein Added: WP_104531867.1 blaLHK-4 Protein Added: WP_104531868.1 blaLHK-5 Protein Added: WP_104531869.1 blaLHK-6 Protein Added: WP_106672612.1 blaCMY-150 Protein Added: WP_106924209.1 blaCTX-M-213 Protein Added: WP_109544237.1 tet(S) Protein Added: WP_109545031.1 dfrA14 Protein Added: WP_109545032.1 qnrB11 Protein Added: WP_109545033.1 vanY-D Protein Added: WP_109545034.1 qnrB22 Protein Added: WP_109545035.1 qacF Protein Added: WP_109545038.1 tet(33) Protein Added: WP_109545039.1 blaSTA-1 Protein Added: WP_109545040.1 chrB Protein Added: WP_109545041.1 aph(3'')-Ib Protein Added: WP_109545042.1 blaORR-1 Protein Added: WP_109545044.1 blaKPC-34 Protein Added: WP_109545045.1 qnrD3 Protein Added: WP_109545046.1 qnrB81 Protein Added: WP_109545047.1 qnrB82 Protein Added: WP_109545048.1 blaOXA-542 Protein Added: WP_109545049.1 blaNDM-20 Protein Added: WP_109545050.1 blaCRH-2 Protein Added: WP_109545051.1 blaCRH-3 Protein Added: WP_109545053.1 blaIMP-73 Protein Added: WP_109545054.1 mcr-4.5 Protein Added: WP_109545055.1 mcr-4.4 Protein Added: WP_109545056.1 mcr-1.13 Protein Added: WP_109545057.1 mcr-5.2 Protein Added: WP_109545058.1 mcr-4.2 Protein Added: WP_109545059.1 blaTEM-232 Protein Added: WP_109545060.1 blaCTX-M-208 Protein Added: WP_109545061.1 blaCTX-M-209 Protein Added: WP_109545062.1 blaCTX-M-210 Protein Added: WP_109545063.1 blaCTX-M-211 Protein Added: WP_109545064.1 blaCTX-M-212 Protein Added: WP_109545065.1 blaCMY-161 Protein Added: WP_109545066.1 blaFOX-16 Protein Added: WP_109545067.1 blaDHA-27 Protein Added: WP_109545068.1 blaDHA-26 Protein Added: WP_109545069.1 blaCTX-M-214 Protein Added: WP_109545070.1 mcr-3.12 Protein Added: WP_109545071.1 blaOXA-649 Protein Added: WP_109545072.1 blaOXA-641 Protein Added: WP_109545073.1 blaFRI-5 Protein Added: WP_109545074.1 blaGPC-1 Protein Added: WP_109545075.1 blaOXA-619 Protein Added: WP_109545076.1 blaOXA-620 Protein Added: WP_109545077.1 blaOXA-636 Protein Added: WP_109545078.1 blaOXA-635 Protein Added: WP_109545079.1 blaOXA-631 Protein Added: WP_109545080.1 blaOXA-626 Protein Added: WP_109545081.1 blaOXA-627 Protein Added: WP_109545082.1 blaOXA-633 Protein Added: WP_109545083.1 blaOXA-628 Protein Added: WP_109545084.1 blaOXA-634 Protein Added: WP_109545085.1 blaOXA-630 Protein Added: WP_109545086.1 blaOXA-632 Protein Added: WP_109545087.1 blaOXA-608 Protein Added: WP_109545088.1 blaOXA-584 Protein Added: WP_109545089.1 blaOXA-585 Protein Added: WP_109545090.1 blaOXA-586 Protein Added: WP_109545091.1 blaOXA-577 Protein Added: WP_109545092.1 blaOXA-587 Protein Added: WP_109545093.1 blaOXA-596 Protein Added: WP_109545094.1 blaOXA-600 Protein Added: WP_109545095.1 blaOXA-588 Protein Added: WP_109545096.1 blaOXA-589 Protein Added: WP_109545097.1 blaOXA-593 Protein Added: WP_109545098.1 blaOXA-599 Protein Added: WP_109545099.1 blaOXA-610 Protein Added: WP_109545100.1 blaOXA-612 Protein Added: WP_109545101.1 blaOXA-598 Protein Added: WP_109545102.1 blaOXA-607 Protein Added: WP_109545103.1 blaOXA-590 Protein Added: WP_109545104.1 blaOXA-604 Protein Added: WP_109545105.1 blaOXA-602 Protein Added: WP_109545106.1 blaOXA-606 Protein Added: WP_109545107.1 blaOXA-582 Protein Added: WP_109545108.1 blaOXA-605 Protein Added: WP_109545109.1 blaOXA-640 Protein Added: WP_109545110.1 blaOXA-616 Protein Added: WP_109545111.1 blaOXA-613 Protein Added: WP_109545112.1 blaOXA-622 Protein Added: WP_109545113.1 blaOXA-618 Protein Added: WP_109545114.1 blaOXA-617 Protein Added: WP_109545115.1 blaOXA-615 Protein Added: WP_109545116.1 blaOXA-621 Protein Added: WP_109791184.1 blaTEM-233 Protein Added: WP_109791185.1 blaPDC-251 Protein Added: WP_109791186.1 blaPDC-252 Protein Added: WP_109791187.1 blaPDC-253 Protein Added: WP_109791188.1 blaPDC-254 Protein Added: WP_109791189.1 blaPDC-255 Protein Added: WP_109791190.1 blaPDC-256 Protein Added: WP_109791191.1 blaPDC-257 Protein Added: WP_109791192.1 blaPDC-258 Protein Added: WP_109791193.1 blaPDC-259 Protein Added: WP_109791194.1 blaPDC-260 Protein Added: WP_109791195.1 blaPDC-261 Protein Added: WP_109791196.1 blaPDC-262 Protein Added: WP_109791197.1 blaPDC-263 Protein Added: WP_109791198.1 blaPDC-264 Protein Added: WP_109791199.1 blaPDC-265 Protein Added: WP_109791200.1 blaPDC-266 Protein Added: WP_109791201.1 blaPDC-267 Protein Added: WP_109791202.1 blaPDC-268 Protein Added: WP_109791203.1 blaPDC-270 Protein Added: WP_109791204.1 blaPDC-272 Protein Added: WP_109791205.1 blaPDC-273 Protein Added: WP_109791206.1 blaPDC-274 Protein Added: WP_109791207.1 blaIMP-74 Protein Added: WP_109791208.1 blaIMP-75 Protein Added: WP_109791209.1 blaCTX-M-216 Protein Added: WP_109791210.1 blaTEM-234 Protein Added: WP_109791211.1 blaCTX-M-217 Protein Added: WP_109791212.1 blaSHV-204 Protein Added: WP_109791213.1 blaNDM-22 Protein Added: WP_109791214.1 blaCTX-M-218 Protein Added: WP_109791215.1 blaCMY-160 Protein Added: WP_109791216.1 blaOXA-654 Protein Added: WP_109997726.1 qnrA9 Protein Added: WP_110092882.1 blaCTX-M-219 Protein Added: WP_111273842.1 mcr-3.13 Protein Added: WP_111273843.1 mcr-3.14 Protein Added: WP_111273844.1 mcr-3.15 Protein Added: WP_111273845.1 mcr-3.16 Protein Added: WP_111273846.1 mcr-3.17 Protein Added: WP_111273847.1 mcr-3.18 Protein Added: WP_111273848.1 blaGES-35 Protein Added: WP_111273849.1 blaGES-36 Protein Added: WP_111273850.1 blaGES-37 Protein Added: WP_111273851.1 blaCMY-162 Protein Added: WP_111273852.1 blaKPC-35 Protein Added: WP_111672883.1 blaPDC-275 Protein Added: WP_111672884.1 blaPDC-294 Protein Added: WP_111672885.1 blaPDC-295 Protein Added: WP_111672886.1 blaPDC-296 Protein Added: WP_111672887.1 blaPDC-297 Protein Added: WP_111672888.1 blaPDC-299 Protein Added: WP_111672889.1 blaPDC-300 Protein Added: WP_111672890.1 blaPDC-276 Protein Added: WP_111672891.1 blaPDC-277 Protein Added: WP_111672892.1 blaPDC-279 Protein Added: WP_111672893.1 blaPDC-280 Protein Added: WP_111672894.1 blaPDC-281 Protein Added: WP_111672895.1 blaPDC-282 Protein Added: WP_111672896.1 blaPDC-283 Protein Added: WP_111672897.1 blaPDC-284 Protein Added: WP_111672898.1 blaPDC-287 Protein Added: WP_111672899.1 blaPDC-288 Protein Added: WP_111672900.1 blaPDC-289 Protein Added: WP_111672901.1 blaPDC-290 Protein Added: WP_111672902.1 blaCTX-M-220 Protein Added: WP_111672903.1 blaPDC-291 Protein Added: WP_111672904.1 blaPDC-292 Protein Added: WP_111672905.1 blaPDC-293 Protein Added: WP_111672906.1 blaCMY-163 Protein Added: WP_111672907.1 blaOXA-657 Protein Added: WP_111672908.1 blaPDC-301 Protein Added: WP_111672909.1 blaPDC-302 Protein Added: WP_111672910.1 blaPDC-303 Protein Added: WP_111672911.1 blaKPC-23 Protein Added: WP_111672912.1 blaNDM-23 Protein Added: WP_111672913.1 blaNDM-24 Protein Added: WP_111672914.1 blaVIM-57 Protein Added: WP_111690897.1 cfr(B) Protein Added: WP_111690898.1 cfr(C) Protein Modified: WP_011987126.1 cfrC updated to WP_011987126.1 cfr-Cb Protein Modified: WP_063854808.1 qnrS updated to WP_063854808.1 qnrS10 HMM Removed: NF000031.1 MFS_efflux_LmrA HMM Removed: NF000040.1 172051428_tet HMM Removed: NF000058.1 Erm41 HMM Removed: NF000060.1 MFS_efflux_LmrB HMM Removed: NF000106.1 40850658_otr HMM Removed: NF000131.1 MATE_multi_MepA HMM Removed: NF000140.3 AAC_6p_Salmo HMM Removed: NF000217.1 MATE_multi_FepA HMM Removed: NF000247.1 MexA HMM Removed: NF000249.1 MexE HMM Removed: NF000250.1 MexH HMM Removed: NF000251.1 MexW-MexI HMM Removed: NF000252.1 MexX HMM Removed: NF000263.1 MATE_multi_NorM HMM Removed: NF000282.2 RND_permease_1 HMM Removed: NF000313.1 adeA-adeI HMM Removed: NF000314.1 adeB HMM Removed: NF000315.1 adeC-adeK-oprM HMM Removed: NF000334.3 drrA HMM Removed: NF000336.1 emrE HMM Removed: NF000342.3 glpA_Cterm HMM Removed: NF000344.1 macA HMM Removed: NF000345.1 macB HMM Removed: NF000349.1 mfpA_AE000516.2 HMM Removed: NF000352.1 norA HMM Removed: NF000357.1 romA HMM Removed: NF000391.1 EmrB HMM Removed: NF010314.2 PRK13751.2 HMM Removed: NF012135.0 ANT_3pp_9_crypt HMM Removed: NF012144.2 ramA_TF HMM Removed: NF012163.2 BaeS_SmeS HMM Removed: NF012168.1 BlaI_of_BCL HMM Removed: NF012198.0 MarA_TF HMM Removed: NF012208.0 SDR_dihy_bifunc HMM Removed: NF012226.0 AdeS_HK HMM Removed: NF012227.0 AdeR_RR HMM Removed: NF012228.1 RobA_TF HMM Removed: NF028537.1 P_eth_NH2_trans HMM Removed: NF030466.0 TIGR02052 HMM Removed: NF030467.0 TIGR02053 HMM Removed: NF033086.2 penta_rpt_Qnr HMM Removed: NF033124.1 estX HMM Removed: NF033134.0 cmlA_floR HMM Removed: NF033138.1 RND-peri-MexC HMM Removed: NF033142.1 efflux_OM_AdeC HMM Removed: NF033143.1 efflux_OM_AdeK HMM Removed: NF033184.1 B3_Acin_new1 HMM Removed: NF033480.1 bifunc_MprF HMM Removed: NF033553.1 MerP_Gpos HMM Removed: NF033555.1 lyase_MerB HMM Removed: NF033556.1 MerTP_fusion HMM Removed: NF033560.1 merT_RC607 HMM Removed: NF033565.0 trans_MerF HMM Removed: NF033606.1 heat_AAA_ClpK HMM Removed: NF033607.0 disagg_AAA_ClpG HMM Removed: NF033617.1 RND_permease_2 HMM Removed: NF033627.1 intimin_all HMM Removed: NF033636.1 acid_shock_Asr HMM Modified: NF033408.2 polymyxin_MCR3 updated to NF033408.5 polymyxin_MCR3 Family Removed: - cfrC Family Added: - cfr(B) Family Added: - cfr(C) Family Added: - cfr-Cb Family Changed: NF033408.2 mcr-3 updated to NF033408.5 mcr-3 --------------------------------------------------------------------- Changes included in 2018-05-15.1 --------------------------------------------------------------------- - Data Changes: Protein Removed: WP_010886396.1 lmr(B) HMM Added: NF033614.1 APH_6_Ic_gen HMM Added: NF033617.1 RND_permease_2 HMM Added: NF033626.1 blaBKC_GPC HMM Added: NF033627.1 intimin_all HMM Added: NF033636.1 acid_shock_Asr HMM Modified: NF000011.1 APH_6_Ic updated to NF000011.2 APH_6_Ic HMM Modified: NF000221.3 FosA updated to NF000221.4 FosA HMM Modified: NF000282.1 RND_permease_1 updated to NF000282.2 RND_permease_1 HMM Modified: NF000428.2 blaFRI updated to NF000428.4 blaFRI HMM Modified: NF033582.0 blaALI updated to NF033582.2 blaALI Family Removed: NF000060.1 lmr(B) Family Added: NF033626.1 blaBKC_GPC Family Added: - blaGPC - Algorithm Changes: - Partial proteins identified as "Method" PARTIAL if length of blast alignment > 50% and < 90% of database protein. --------------------------------------------------------------------- Changes included in 2018-05-08.1 RELEASE CANDIDATE --------------------------------------------------------------------- - Addition of handling for genbank plasmid gff --------------------------------------------------------------------- Changes included in 2018-04-16.1 --------------------------------------------------------------------- - Addition of file format checking for FASTA and GFF files before AMRFinder blast and HMM searches are run - Altered format of fam.tab file to include NF accessions for families - Removal of non-reportable families from fam.tab