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<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01//EN" "http://www.w3.org/TR/html4/transitional.dtd"> <html> <head> <link rel="stylesheet" type="text/css" href="logo.css" > <title>CodonLogo - Examples</title> <meta name="author" content="Gavin E. Crooks" > <meta name="author" content="Steven E. Brenner" > <meta name="ID" content="$ID:" > <style type="text/css"> img { display: block; margin-left: auto; margin-right: auto } </style> </head> <body> <table width="80%" border = '0' cellspacing='0' cellpadding='1' align="center"> <tr><td > <h1> CodonLogo 1.0: Examples</h1> </td><td align = "right"> · <a href="./">about</a> · <a href="create.cgi">create</a> · <a class="selected" href="examples.html">examples</a> · <a href="manual.html">manual</a> · <br> </td></tr> <tr><td colspan="2" class="discourse" > <ul> <li> <a href="#CAP">CAP HTH motif</a> </li> <li> <a href="#trans">Transcription Factors</a> </li> <li> <a href="#promoters"><i>E. coli</i> Promoters</a> </li> <li> <a href="#globins">Globins</a> </li> <li> <a href="#HTH">HTH motif</a> </li> <li> <a href="#splice">Splice Signals</a> </li> </ul> <p> The <strong>Edit Logo</strong> buttons will transfer the relevant sequence data to the <a class="in" href="create.cgi">Logo creation form</a>. There you can examine the sequence data and recreate the logo for yourself. <!--Additional examples can be found at the <a href="http://www.lecb.ncifcrf.gov/~toms/sequencelogo.html">Sequence Logo Gallery</a>.--> </p> <!--<hr > <a name="CAP"></a> <a name="CAP_HTH"></a> <h2>Catobolite Activator Protein (CAP)</h2> <img alt="Catobolite Activator Protein (CAP) Logo" src="examples/cap_hth.png"> <p> The helix-turn-helix motif from the CAP family of homodimeric DNA binding proteins. CAP (Catabolite Activator Protein, also known as CRP for cAMP Receptor Protein) is a transcription promoter that binds at more than 100 sites within the <i>E. coli</i> genome. Residues 1-7 form the first helix, 8-11 the turn and 12-20 form the DNA recognition helix. The glycine at position 9 appears to be critical in forming the turn. Positions 4, 8, 10, 15 and 19 are partially or completely buried, and therefore tend to be populated by hydrophobic amino acids, which are colored black. Positions 11-14, 17 and 20 interact directly with bases in the major groove and are critical to the sequence specific binding of the protein. The data for this logo consists of 100 sequences from the full Pfam alignment of this family (Accession number PF00325). A few sequences with rare insertions were removed for convenience. </p>--> <!-- # Pfam 7.1 crp # Accession number: PF00325 # Bacterial regulatory proteins, crp family # # Description # Numerous bacterial transcription regulatory # proteins bind DNA via a helix-turn-helix (HTH) # motif. These proteins are very diverse, but # for convenience may be grouped into subfamilies on # the basis of sequence similarity. One such # family groups together a range of proteins, including # anr, crp, clp, cysR, fixK, flp, fnr, fnrN, hlyX and # ntcA [MEDLINE:91064083], [MEDLINE:93181282], # [MEDLINE:91008963]. Within this family, the HTH motif is situated # towards the C-terminus. # This is the full Pfam alignment, less a couple of inserts # 102 sequences. # # http://pfam.wustl.edu/cgi-bin/getdesc?name=crp # # Introduction to protein structure, 1st edition, contains # some more information. # First number is sequence number is -5 # First Helix: 1-7, Turn: 8-11, 2nd (DNA recognition) 12-20 # --> <!-- <form method="post" action="create.cgi"> <input type="submit" name="cmd_edit" value="Edit Logo" > <input type="hidden" name="logo_title" value="The DNA-binding helix-turn-helix motif of the CAP family" > <input type="hidden" name="first_index" value="-5" > <input type="hidden" name="logo_start" value="1" > <input type="hidden" name="logo_end" value="20" > <input type="hidden" name="show_xaxis" value="true" > <input type="hidden" name="show_yaxis" value="true" > <input type="hidden" name="show_errorbars" value="true" > <input type="hidden" name="show_fineprint" value="true" > <input type="hidden" name="scale_width" value="true" > <input type="hidden" name="sequences" value=">Q9EXQ1/196-227 LTMT.-RGDIGNYLGLTVETISRLLGRFQKLGVL >Q46158/72-92 LTMT.-RGDIGNYLGLTVETISR----------- >Q46157/72-92 LTMT.-RGDIGNYLGLTVETISR----------- >Q46159/72-92 LTMT.-RGDIGNYLGLTVETISR----------- >Q47948/72-92 LTMT.-RGDIGNYLGLTVETISR----------- >FNR_HAEIN/196-227 LTMT.-RGDIGNYLGLTVETISRLLGRFQKLGVI >ETRA_SHEPU/193-224 LTMT.-RGDIGNYLGLTVETISRLLGRFQKSGLI >FNR_SALTY/193-224 LTMT.-RGDIGNYLGLTVETISRLLGRFQKSGML >Q9LA24/207-238 LTMT.-RGDIGNYLGLTVETISRLLGRFQKSGML >Q9AQ50/193-224 LTMT.-RGDIGNYLGLTVETISRLLGRFQKSGML >FNR_ECOLI/193-224 LTMT.-RGDIGNYLGLTVETISRLLGRFQKSGML >HLYX_ACTPL/192-223 LTMT.-RGDIGNYLGLTIETISRLLGRFQKSGMI >O31204/192-223 LTMT.-RGDIGNYLGLTIETISRLLGRFQKSGMI >Q9L801/192-223 LTMT.-RGDIGNYLGLTIETISRLLGRFQKSGMI >Q9KS27/193-224 LTMT.-RGDIGNYLGLTVETISRLLGRFQKSEIL >Q9CMY2/212-243 LTMT.-RGDIGNYLGLTVETISRLLGRLQKMGIL >Q44500/188-219 LAMS.-RNEIGNYLGLAVETVSRVFSRFQQNELI >ANR_PSEAE/188-219 LAMS.-RNEIGNYLGLAVETVSRVFTRFQQNGLI >O85222/188-219 LSMS.-RNEIGNYLGLAVETVSRVFTRFQQNELI >FNRA_PSEST/188-219 LPMS.-RNEIGNYLGLAVETVSRVFTRFQQNGLL >BTR_BORPE/186-217 VRMS.-REEIGNYLGLTLETVSRLFSRFGREGLI >Q9JQQ8/187-218 LRMS.-REEIGSYLGLKLETVSRTLSKFHQEGLI >O69245/180-211 LPMC.-RRDIGDYLGLTLETVSRALSQLHTQGIL >Q9AMR4/161-192 LPMS.-RRDIADYLGLTVETVSRAVSQLHTDGVL >FIXK_BRAJA/185-216 LPMS.-RQDIADYLGLTIETVSRTFTKLERHGAI >AADR_RHOPA/187-218 LPMG.-RQDIADFLGLTIETVSRTFTKLEREKLI >FIXK_RHIME/159-190 LPMS.-RQDIADYLGLTIETVSRVVTKLKERSLI >FIXK_AZOCA/196-227 LAMS.-RQDIADFLGLTIETVSRTLTYLEEQGTI >Q9AA54/164-195 VPMS.-RQDMADYLGLTIETVSRTLTSLQDEGLI >Q988V4/163-194 LPMS.-RMDIGDYLGLTIETVSRVFTRLKDKGVI >Q53170/175-206 LPMT.-RLDVADYLGMTIETVSRTITKLAGSGVI >Q989I4/189-220 LPLT.-RADISDFLGLTNETVSRQLTRLRADGVI >Q988R0/189-220 LPLT.-RADIADFLGLTIETVSRQLTRLRTDGLI >O06655/187-218 LPLS.-RAEIADFLGLTIETVSRKLTKLRKSGVI >O86069/185-216 LPLS.-RAEIADFLGLTIETVSRQLTRLRKEGVI >O86067/187-218 LPLS.-RAEIADFLGLTIETVSRQMTRLRKWGVI >Q52775/187-218 LPLS.-RAEIADFLGLTIETVSRQMTRLRKSGVI >FX24_RHILV/187-218 LPLS.-RAEIADFLGLTIETVSRQMTRLRKIGVI >FNRL_RHOSH/187-218 LPLT.-REEMADYLGLTLETVSRQVSALKRDGVI >Q51677/188-219 LPLT.-REAMADYLGLTLETVSRQMSALKREGVI >O33961/187-218 LPLT.-REAMADYLGLTLETVSRQMSALKRDGVI >O87372/155-185 -SIS.-RADMADFLGLTTETVSRLLSAFHREQLI >P95599/188-221 LRVSmNRQDIADHLGLTIETLAHTVTKLASRNIV >Q52823/185-216 VPMS.-RQDIADHLGLTIETVSRTLTKLASRNVV >Q9FDG3/192-223 VPMN.-RQDIADHLGLTIETVSRTITKLAARNIV >O84975/207-238 LRMS.-REDIASYLGLRLETVCRSVARLRAQDVV >Q53240/186-217 FPIT.-RQNISEMTGTTLHTVSRLLSAWEREGIV >O52578/162-191 --IS.-RQDIAEMTGTTLHTVSRILSAWEQLGFV >Q9KWP8/153-184 FPIT.-KQDIAEMTGTTLHTVSRILTGWEAQGFV >O66781/189-220 LPLT.-RQDIAEMTGTTVETTIRVMSKWKKQGII >Q982N1/28-58 -PIA.-RGEIASRVGLTVQTVSTIVRELEEQGYI >P96094/179-210 LPAK.-KAMIAARLGLTPETFSRVLKRLREEHLI >FLP_LACCA/168-199 VPMA.-WTQLADYLGTTPETVSRTLKRLAEEKLI >Q97IX9/173-206 INMElSITYLADMLGSKRETVSRQLKLLTEKNLV >Q9CE44/171-202 IPMK.-LKELANYIGTSPETISRKIKVFEENKII >Q9S392/178-209 IPMK.-MKDLATFIGTTPETISRKFKILEEKGFI >Q9S393/178-209 IPMT.-LKDLSAFIGTTPETISRKLRLLEEKGLV >Q98GX3/209-240 LPLS.-QAELADVLGLSVVHMNRVIGALRKVGVV >Q9XDD3/182-213 CPLT.-QGELADALGLTPIHINRMLRELREDNLL >NTCA_ANASP/172-203 LKLS.-HQAIAEAIGSTRVTVTRLLGDLREKKMI >NTCA_SYNP7/171-202 LKLS.-HQAIAEAIGSTRVTVTRLLGDLRESKLI >NTCA_SYNY3/174-205 LKLS.-HQAIAEAIGSTRVTVTRLLGDLREGNMI >P94611/175-206 LKLS.-HQAIAEAIGSTRVTVTRLLGDLRQEEMI >Q9L627/170-201 LKLS.-HQAIAEAIGSTRVTVTRLLGDLRQDEMI >Q9AG80/172-203 LKLS.-HQAIAEAIGSTRVTVTRLLGDLRQDKMI >O30778/173-204 LRLS.-HQAIAEAIGSTRVTITRLLGDLRNSGLV >Q9KI45/189-220 FPLT.-HAQIGSAIGSTRVTVTRLMGKLRQRGLI >CYSR_SYNP7/152-183 IPLT.-HQVIAELSGSTRVTTTRLLGEFRQAGRI >CYSR_SYNY3/160-191 VRLT.-HQMLANAIGTTRVTVTRLLGEFQTQGKV >Q55322/177-208 LRLT.-HQEMASALSTTRVTVTRVIGLLRDEGWL >Q9RTV7/201-231 -RIS.-HQDLAHSVGSTRETITKLLGDFRTRGLL >Q9TLZ6/157-188 IYIS.-QHDIASILSTTRSTITRLINQLRKDNII >FNR_BACSU/174-205 IVLT.-NQDLAKFCAAARESVNRMLGDLRKKGVI >O86128/173-204 IVLT.-NQDLAKFCAAARESINRMLSDLRKNGVI >Q9KG81/173-204 IVLT.-NQELANFCAAARESVNRMLGELRKLGVI >CRP_PASMU/165-196 IKIT.-RQEIGQMVGCSRETVGRILKMLEDQHLI >Q48301/170-201 IKIT.-RQEIGQMVGCSRETVGRILKMLEDQHLI >CRP_HAEIN/180-211 IKIT.-RQEIGQMVGCSRETVGRIIKMLEDQNLI >Q51859/180-211 IKIT.-RQEIGQMVGCSRETVGRIIKMLEDEGLI >Q9F435/166-197 IKIT.-RQEIGQIVGCSRETVGHILKMLEDQNLI >CRP_ECOLI/166-197 IKIT.-RQEIGQIVGCSRETVGRILKMLEDQNLI >CRP_SALTY/166-197 IKIT.-RQEIGQIVGCSRETVGRILKMLEDQNLI >O07097/166-197 IKIT.-RQEIGQIVGCSRETVGRILKMLEDQNLI >Q9ALY5/166-197 IKIT.-RQEIGQIVGCSRETVGRILKMLEEQNLI >O34015/166-197 IKIT.-RQEIGQIVGCSRETVGRILKMLEEQNLI >Q9KNW6/166-197 IKIT.-RQEIGQIVGCSRETVGRILKMLEEQNLI >CLP_XANCP/186-217 LRVS.-RQELARLVGCCAQMAGRVLKKLQADGLL >Q9PD39/185-216 LRVS.-RQELARLVGCSREMAGRVLKKLQADGLL >Q9S6B5/186-217 LRVS.-RQELARLVGCSREMAGRVLKKLQADGLL >P71977/33-62 --LS.-QAEIGERVGMARSTVSRILNALEDEGLV >O28174/36-67 VKIS.-SKELAEHIGQSLQTAARKLKELEDEGLI >Q9CB91/174-204 -DLT.-QEEIAQLVGASRETVNKALADFAHRGWI >O69644/174-204 -DLT.-QEEIAQLVGASRETVNKALADFAHRGWI >Q9XA42/174-204 -DLT.-QEELAQLVGASRETVNKALADFAQRGWL >Q97TL8/136-167 INCT.-HEDIGKAVGVSRVTVSRTLNKFSQYQWI >Q99YT6/175-206 FQLT.-TTDIAQISGTTRETVSHVLRDLKKQELI >Q9RRX0/176-209 LNLKlNQEDIARMVGATRETVSHSLSRLKKGGAI >Q9K5F3/178-209 CPIT.-AAEIAKISGTSRETVSAVLKKLRCEGVI >P73234/185-215 -NLP.-HRETAMLSGVTRETVTRTLGKLEKKGLI >P74171/182-212 -NLP.-HRELSSISGLARETVTRCLTKLEKRGLI >Q981X4/78-109 AKVT.-HDQIAAMVGSTRQWVTMMMKRFQKEGLV " > </form>--> <!--<!--<img alt="CAP Binding Site Logo" src="examples/cap_dna.png" > <p> The two DNA recognition helixes of the CAP homodimer insert themselves into consecutive turns of the major groove. Several consequences can be observed in this CAP binding site logo. The logo is approximately palindromic, which provides two very similar recognition sites, one for each subunit of the dimer. However, the binding site is not perfectly symmetric, possible due to the inherent asymmetry of the operon promoter region. The displacement of the two parts is 11 base pairs, or approximately one full turn of the DNA helix. Additional interactions between the protein and the first and last two bases occur within the DNA minor groove, where it is difficult for the protein to distinguish A from T, or G from C. The data for this logo consists of 59 binding sites determined by <a href="#footprinting">DNA footprinting</a>. <cite> Robison, K., McGuire, A. M., Church, G. M. A comprehensive library of DNA-binding site matrices for 55 proteins applied to the complete <i>Escherichia coli</i> K12 genome. Journal of Molecular Biology (1998) 284, 241-254. </cite> </p> <form method="post" action="create.cgi"> <input type="submit" name="cmd_edit" value="Edit Logo" > <input type="hidden" name="first_index" value="-10" > <input type="hidden" name="show_xaxis" value="true" > <input type="hidden" name="show_yaxis" value="true" > <input type="hidden" name="show_errorbars" value="true" > <input type="hidden" name="show_fineprint" value="true" > <input type="hidden" name="scale_width" value="true" > <input type="hidden" name="logo_title" value="58 CAP Binding Sites" > <input type="hidden" name="sequences" value=" >aldB -18->4 attcgtgatagctgtcgtaaag >ansB 103->125 ttttgttacctgcctctaactt >araB1 109->131 aagtgtgacgccgtgcaaataa >araB2 147->169 tgccgtgattatagacactttt >cdd 1 107->129 atttgcgatgcgtcgcgcattt >cdd 2 57->79 taatgagattcagatcacatat >crp 1 115->137 taatgtgacgtcctttgcatac >crp 2 gaaggcgacctgggtcatgctg >cya 151->173 aggtgttaaattgatcacgttt >cytR 1 125->147 cgatgcgaggcggatcgaaaaa >cytR 2 106->128 aaattcaatattcatcacactt >dadAX 1 95->117 agatgtgagccagctcaccata >dadAX 2 32->54 agatgtgattagattattattc >deoP2 1 75->97 aattgtgatgtgtatcgaagtg >deoP2 2 128->150 ttatttgaaccagatcgcatta >fur 136->158 aaatgtaagctgtgccacgttt >gal 56->78 aagtgtgacatggaataaatta >glpACB (glpTQ) 1 54->76 ttgtttgatttcgcgcatattc >glpACB (glpTQ) 2 94->116 aaacgtgatttcatgcgtcatt >glpACB (glpTQ) 144->166 atgtgtgcggcaattcacattt >glpD (glpE) 95->117 taatgttatacatatcactcta >glpFK 1 120->142 ttttatgacgaggcacacacat >glpFK 2 95->117 aagttcgatatttctcgttttt >gut (srlA) 72->94 ttttgcgatcaaaataacactt >ilvB 87->109 aaacgtgatcaacccctcaatt >lac 1 (lacZ) 88->110 taatgtgagttagctcactcat >lac 2 (lacZ) 16->38 aattgtgagcggataacaattt >malEpKp1 110->132 ttgtgtgatctctgttacagaa >malEpKp2 139->161 TAAtgtggagatgcgcacaTAA >malEpKp3 173->195 TTTtgcaagcaacatcacgAAA >malEpKp4 205->227 GACctcggtttagttcacaGAA >malT 121->143 aattgtgacacagtgcaaattc >melR 52->74 aaccgtgctcccactcgcagtc >mtl 302->324 TCTTGTGATTCAGATCACAAAG >nag 156->178 ttttgtgagttttgtcaccaaa >nupG2 97->119 aaatgttatccacatcacaatt >nupG1 47->69 ttatttgccacaggtaacaaaa >ompA 166->188 atgcctgacggagttcacactt >ompR 161->183 taacgtgatcatatcaacagaa >ptsH A 316->338 Ttttgtggcctgcttcaaactt >ptsH B 188->210 ttttatgatttggttcaattct >rhaS (rhaB) 161->183 aattgtgaacatcatcacgttc >rot 1 (ppiA) 182->204 ttttgtgatctgtttaaatgtt >rot 2 (ppiA) 129->151 agaggtgattttgatcacggaa >tdcA 60->82 atttgtgagtggtcgcacatat >tnaL 73->95 gattgtgattcgattcacattt >tsx 2 146->168 gtgtgtaaacgtgaacgcaatc >tsx 1 107->129 aactgtgaaacgaaacatattt >uxuAB 165->187 TCTTGTGATGTGGTTAACCAAT " > </form> <hr ><a name="trans"></a> <h2><i>E. coli</i> Transcription Factor Binding Sites</h2> <p> The following logos (along with the <a href="#CAP">CAP logo</a> above) display a selection of <i>E. coli</i> transcription factor binding sites determined by DNA footprinting. This data has been collated in the <a href="http://arep.med.harvard.edu/dpinteract/">DPInteract</a> database and has been used to <a href="http://arep.med.harvard.edu/ecoli_matrices/">search for additional binding sites</a> within the <i>E. coli</i> genome. </p> <p> <a name="footprinting"></a> <cite> Robison, K., McGuire, A. M., Church, G. M. A comprehensive library of DNA-binding site matrices for 55 proteins applied to the complete <i>Escherichia coli</i> K12 genome. Journal of Molecular Biology (1998) 284, 241-254. </cite> </p> <a name="LexA"></a> <img alt ="" src="examples/lexA.png" ><br > <form method="post" action="create.cgi"> <input type="submit" name="cmd_edit" value="Edit Logo" > LexA repressor is closely related to CAP, and has similar DNA protein interactions. <input type="hidden" name="logo_title" value="19 LexA Binding Sites" > <input type="hidden" name="first_index" value="-9" > <input type="hidden" name="show_xaxis" value="true" > <input type="hidden" name="show_yaxis" value="true" > <input type="hidden" name="show_errorbars" value="true" > <input type="hidden" name="show_fineprint" value="true" > <input type="hidden" name="scale_width" value="true" > <input type="hidden" name="sequences" value=" >dinD 32->52 aactgtatataaatacagtt >dinG 15->35 tattggctgtttatacagta >dinH 77->97 tcctgttaatccatacagca >dinI 19->39 acctgtataaataaccagta >lexA-1 28->48 tgctgtatatactcacagca >lexA-2 7->27 aactgtatatacacccaggg >polB(dinA) 53->73 gactgtataaaaccacagcc >recA 59->79 tactgtatgagcatacagta >recN-1 49->69 tactgtatataaaaccagtt >recN-2 27->47 tactgtacacaataacagta >recN-3 9-29 TCCTGTATGAAAAACCATTA >ruvAB 49->69 cgctggatatctatccagca >sosC 18->38 tactgatgatatatacaggt >sosD 14->34 cactggatagataaccagca >sulA 22->42 tactgtacatccatacagta >umuDC 20->40 tactgtatataaaaacagta >uvrA 83->103 tactgtatattcattcaggt >uvrB 75->95 aactgtttttttatccagta >uvrD 57->77 atctgtatatatacccagct" > </form> <a name="hns"></a> <!--<img alt ="" src="examples/hns.png" >--> <!--<form method="post" action="create.cgi"> <input type="submit" name="cmd_edit" value="Edit Logo" > H-NS: Histone like, nucleoid-associated DNA-binding protein. <input type="hidden" name="logo_title" value="15 hns Binding Sites" > <input type="hidden" name="first_index" value="-1" > <input type="hidden" name="logo_start" value="1" > <input type="hidden" name="show_xaxis" value="true" > <input type="hidden" name="show_yaxis" value="true" > <input type="hidden" name="show_errorbars" value="true" > <input type="hidden" name="show_fineprint" value="true" > <input type="hidden" name="scale_width" value="true" > <input type="hidden" name="sequences" value=" >hns1 tAGGCTGATTT >hns2 gAAAATTATTT >hns3 gGGAGTTATTC >hns4 aCAAATTATTT >hns5 gCAACAGAGTA >hns6 aCGCCTGAATA >hns7 tCGAGAAAGTT >hns8 tCGCCGGAATT >hns9 tGGCATGAATA >hns10 aTAAAGGAATC >hns11 cTAATTTAATT >hns12 gCAATTAAATT >hns13 tGACATGAATC >hns14 cTGGCTAATTT >hns15 aCAACTGAATT" > </form> <a name="dnaA"></a>--> <!--<img alt="" src="examples/dnaA.png" >--> <!--<form method="post" action="create.cgi"> <input type="submit" name="cmd_edit" value="Edit Logo" > DNA biosynthesis initiation binding protein. <input type="hidden" name="logo_title" value="8 dnaA Binding Sites" > <input type="hidden" name="logo_end" value="14" > <input type="hidden" name="show_xaxis" value="true" > <input type="hidden" name="show_yaxis" value="true" > <input type="hidden" name="show_errorbars" value="true" > <input type="hidden" name="show_fineprint" value="true" > <input type="hidden" name="scale_width" value="true" > <input type="hidden" name="sequences" value=" >dnaA_1 rpoH-1 aatttattcacaagc >dnaA_2 rpoH-2 attttatccacaagt >dnaA_3 nrd gagttatccacaaag >dnaA_4 oriC-R1 ttgttatccacaggg >dnaA_5 oriC-R2 ggggttatacacaac >dnaA_6 oriC-R3 ttctttggataacta >dnaA_7 oriC-R4 gagttatccacagta >dnaA_10 dnaA gatttatccacagga" > </form> --> <!-- <a name="argR"></a> --> <!--<img alt ="" src="examples/argR.png" >--> <!--<form method="post" action="create.cgi"> <input type="submit" name="cmd_edit" value="Edit Logo" > Arginine Repressor. <input type="hidden" name="logo_title" value="17 ArgR Binding Sites" > <input type="hidden" name="first_index" value="-8" > <input type="hidden" name="show_xaxis" value="true" > <input type="hidden" name="show_yaxis" value="true" > <input type="hidden" name="show_errorbars" value="true" > <input type="hidden" name="show_fineprint" value="true" > <input type="hidden" name="scale_width" value="true" > <input type="hidden" name="sequences" value=" >argA-1 32->50 acagaataaaaatacact >argA-2 11->29 ttcgaataatcatgcaaa >argD-1 51->69 agtgattttttatgcata >argD-2 30->48 tgtggttataatttcaca >argECBH-1 26->44, argC 110->128 tatcaatattcatgcagt >argECBH-2 47->65, argC 89->107 tatgaataaaaatacact >argF-1 48->66 aatgaataattacacata >argF-2 27->45 agtgaattttaattcaat >argG-1 73->91 attaaatgaaaactcatt >argG-2 52->70 tttgcataaaaattcagt >argG-3 192->210 tgtgaatgaatatccagt >argI-1 46->64 aatgaataatcatccata >argI-2 25->43 attgaattttaattcatt >argR-1 45->63 tttgcataaaaattcatc >argR-2 24->42 tatgcacaataatgttgt >carAB-1 32->50 tgtgaattaatatgcaaa >carAB-2 11->29 agtgagtgaatattctct" > </form> <hr > <a name="promoters"></a> <h2><i>E. coli</i> Promoters (Transcription Start Signals)</h2> <p> <img alt="" src="examples/ecoli10.png"><br > In prokaryotes the DNA sequence just upstream of the transcription start point contains two important conserved regions. The first such region is centered at around 35bp upstream and is involved in the initial recognition of the gene by RNA polymerase. --> <!--The consensus sequence is TTGACAT, but the logo indicates that a great deal of variation occurs. --> <!--The second region, sometimes referred to as the Pribnow box, is centered at about 10bp upstream. The typical separation between the -35 and -10 sites is 15-18 bp. See <a class="out" href="http://www.lecb.ncifcrf.gov/~toms/papers/baseflip/">baseflip: Strong Minor Groove Base Conservation in Sequence Logos implies DNA Distortion or Base Flipping during Replication and Transcription Initiation</a> for more information. This sequence data was kindly provided by Prof. Julia Brettschneider <juliab@stat.berkeley.edu> </p>--> <!-- <form method="post" action="create.cgi"> <input type="submit" name="cmd_edit" value="Edit Logo" > The -10 region of 350 E. coli promoters <input type="hidden" name="logo_title" value="-10 region of 3E. coli promoters" > <input type="hidden" name="first_index" value="-21" > <input type="hidden" name="logo_start" value="0" > <input type="hidden" name="logo_end" value="7" > <input type="hidden" name="show_xaxis" value="true" > <input type="hidden" name="show_yaxis" value="true" > <input type="hidden" name="show_errorbars" value="true" > <input type="hidden" name="show_fineprint" value="true" > <input type="hidden" name="scale_width" value="true" > <input type="hidden" name="sequences" value="> The -10 hexamers of 350 E.coli promoters gatgacgtggtttacgaccccaTTTAGTagtcaaccgcagtgagtgagtc > ttgaaaccagacgtttcgccccTATTACagactcacaaccacatgatgac > ctggcggcgtagcgatgcgctgGTTACTctgaaaacggtctatgcaaatt > tgacttttagcgcccatatctcCAGAATgccgccgtttgccagaaattcg > gatttacgtcatcattgtgaatTAATATgcaaataaagtgagtgaatatt > agaatacagcttattgaataccCATTATgagttagccattaacgcgtcca > cgacgacggtttacgctttacgTATAGTggcgacaattttttttatcggg > ctgacgctttttatcgcaactcTCTACTgtttctccatacccgttttttt > atccgtttttgtatccagtaacTCTAAAagcatatcgcattcatctggag > ttttttattgaatgtagaatttTATTCTgaatgtgtgggctctctatttt > tattctgaatgtgtgggctctcTATTTTaggattaattaaaaaaatagag > tcttttcacctttcctcctgttTATTCTtattaccccgtgtttatgtctc > attgcttaagcaagatcggacgGTTAATgtgttttacacattttttccgt > gcgccacactaaggtaattcctTATGCTggcaatgtcgtgaccagtgata > tgcagcctgtgctcagcgcgtgTTTCATacgcaagtgcgtatcggcgcgc > tgcattcgctgccgcataccatTATTCTtgatctgacggaagtctttttg > ggacataaggtgaatactttgtTACTTTagcgtcacagacatgaaattgg > ttattgagctttccggcgagagTTCAATgggacaggttccagaaaactca > ttaaaaattgttaacaattttgTAAAATaccgacggatagaacgacccgg > taacacctcgtcaaaatcctgcTATTCTgcccgttgcggtactgggcatt > tctattttatattattccctgtTTTAATtaactctatcagggatggttta > gacagaggccctcaatccaaacGATAAAgggtgatgtgtttactgatatg > tgctatctcgctgacggacaggCAAATTgatgaccagcttttaaaccgac > tttgacatttcttttgcactggTAAACTaaatcacttttttttgtcccag > ttttctcgcgtccgcgatagcgTAAAATagcgccgtaacccccaggtcct > aatttctacctgtttaagcatcTCTGGTagacttcctgtaattgaatcga > tgcagtgctcatagcggtcattTATGTCagacttgtcgttttacagttcg > aacatatctcgcaagcctgtctTGTGTTgacaacattttctgctaaccct > ctctccctgacgcgggataaagTGGTATtctcaaacatatctcgcaagcc > tatatctttaacaatctcaggtTAAAAActttcctgttttcaacgggact > gttgcaaatgaataattacacaTATAAAgtgaattttaattcaataagtg > tgaacgtccaatcaataaccgcTTTAATagataaacaccgctgatgaatg > ttgctttttatcttcagatgaaTAGAATgcggcggattttttgggtttca > gtcataaggtaaaagtctcattTATGATgagttccattggatttacttat > ttaccttatgacaatcggcgagTAGTCTgcctctcattccagagacagac > tacactttatgcttccggctcgTATGTTgtgtggaattgtgagcggataa > cgcaaaacctttcgcggtatggCATGATagcgcccggaagagagtcaatt > taaagttgtcacggccgagactTATAGTcgctttgtttttattttttaat > ttcattcttgaatatttattggTATAGTaaggggtgtattgagattttca > atctcttggccttgctggtcgtTATCCTgcaagctatcactttattggct > taaatctgtcataaatctgacgCATAATgacgtcgcattaatgatcgcaa > tgcagggagagcgccccggcacTAGACTacccgcctcttattttagtctg > acatatttttgtgagcaatgatTTTTATaataggctcctctgtatacgaa > ttacagtaatgtaaccttcccgTAAAATgcccacacactttaaacgccac > tagcgtaacaacaaaagattgtTATGCTtgaaatatggtgatgccgtacc > tcccttgtccccatctctcccaCATCCTgtttttaaccttaaaatggcat > tgaggcaatcgcctgttggtggTATCGTttatcgctttttcaaaaaattc > gattgcagaaatatattgataaTATTATtgataactatttgcatttgcaa > aaatgcaaatagttatcaataaTATTATcaatatatttctgcaatcaatg > tgctggaaaattaatgtgctttTATAGTggcgcttattgttgtcaatatt > attatcactcccttttactggcTAAACCagaaaacttattttatcattca > tcacacactctgtagcagatgaTCTAACaatctgattacagaacatcggc > tgtcagcctgtcccgcttataaGATCATacgccgttatacgttgtttacg > tttcatttaggcgtggcaattcTATAATgatacgcattatctcaagagca > acagttattagtggtagacaagTTTAATaattcggattgctaagtacttg > acaaacattaccaggaaaagcaTATAATgcgtaaaagttatgaagtcggt > tgtaatgattttgtgaacagccTATACTgccgccaggtctccggaacacc > tgggcagcttcttcgtcaaattTATCATgtggggcatccttaccgctctg > ctttaaaaactgcccctgacacTAAGACagtttttaaaggttccttcgcg > ggaaatgggcatcaaaaagagaTAAATTgttctcgatcaaattggctgaa > ttacacattctgacggaagataTAGATTggaagtattgcattcactaaga > gtcacacttttcgcatctttgtTATGCTatggttatttcataccataagc > gtcacacttttcgcatctttgtTATGCTatggttatttcataccataagc > gttttttgttgttaattcggtgTAGACTtgtaaacctaaatcttttcaat > tgtaaaccaaattgaaaagattTAGGTTtacaagtctacaccgaattaac > caaaactggcacgattttttcaTATATGtgaatgtcacgcaggggatcgt > tttttcatcaggttttacgctaAATAATcactgtgttgagtgcacaattt > ttgacggctcgccctaattctcTAAATTgtatttctagagttggcgaggt > cgtgttacaaaaattcttttctTATGATgtagaacgtgcaacgcaattga > caaaaattcttttcttatgatgTAGAACgtgcaacgcaattgatgctcgc > gatggtgaacaagtacgcgaggGAGAATgagcatccattgctgtgtacgc > actcctcacttacacgtaatacTACTTTcgagtgaaaatctacctatctc > ggtggtggtttgttggttgggtTGACATactgggtcatttacctgcgtga > tatggtgctgccggtcgcgatgTTTGTTgccagcggttttgagcacagta > gcaaacctgatggtatgtctggCAGTATggatgagttattctggccgcag > tttctcatctataatgctttgtTAGTATctcgtcgccgacttaataaaga > tttctcatctataatgctttgtTAGTATctcgtcgccgacttaataaaga > tgataaaaccgatagccacaggAATAATgtattacctgtggtcgcaatcg > gagcaagtgattgaaaaagcgcTACAATacgcgcgccagaaattggctct > tggaattttgtaaatctcccgtTACCCTgatagcggacttcccttctgta > ttcaataaattgcgaaacaaggTATACTccagcagttcctgaagatgttt > acgcagcagtagcaaactaagcTATAAAttgcagcgcgaactggagcagc > tgttcagcgtacacgtgttagcTATCCTgcgtgcttcaataaaataaggc > ttgtaagttttcaactacgttgTAGACTttacatcgccaggggtgctcgg > ttcacacttgtaagttttcaacTACGTTgtagactttacatcgccagggg > gttgatctttgttgtcactggaTGTACTgtacatccatacagtaactcac > attagcatcgcatcaggcaatcAATAATgtcagatatgaaaagcggaaac > tggcatatgaaattttgaggatTACCCTacacttataggagttaccttac > acatggttgcacaaagttgcaaCATCATggatatttcacgataacgttaa > aaaatttaatgtaaatggtgtgTTAAATcgattgtgaataaccagcgctt > aaaatttaatgtaaatggtgtgTTAAATcgattgtgaataaccagcgctt > tgtgaataaccagcgcttccggCAGGATacggtcgccctggtaaaacata > aacggcaagtttcgacattgccGATAATaattttttggagactttagatg > catcactctgtcatctttccagTAGAAActaatgtcactgaaatggtgtt > gtcggaatggctggttatccatTAAAATagatcggatcgatataagcaca > tgcaaaggaaaacgtttccgctTATCCTttgtgtccggcaaaaacatccc > tgactctatgacgttacaaagtTAATATgcgcgccctatgcaaaaggtaa > tttcagagattatgaattgccgCATTATagcctaataacgcgcatctttc > ttcatgacggcaaacaatagggTAGTATtgacaagccaattacaaatcat > tgatctgctggcaagaacagacTACTGTatataaaaacagtataacttca > tgaataatattttcaactgagtTATCAAgatgtgattagattattattct > gatcatgcagctagtgcgatccTGAACTaaggttttctgatacttgaata > gatgcggtgctttcctggctgtTAGAATacgccccgtcgcgcctgactgg > agcgttaccgtccgctatcgtcTATGTTcaagttgtcttaattgccagaa > tttattgatcttacgcatcctgTATGATgcaagcagactaaccctatcaa > catcaaattgcctttagctacaGACACTaaggtggcagacatcgaaacga > gtttcagagcgttaccttgcccTTAAACattagcaatgtcgatttatcag > tgcacaactgaatttaaggctcTATTATtacctcaacaaaccaccccaat > taatgtagccaccaaatcatacTACAATttattaactgttagctataatg > tgctgaagaataattgaaatgaTATTATtaattccactgcctttggtaga > gaatatgattgctatttgcattTAAAATcgagacctggtttttctactga > cgtgacattttaacacgtttgtTACAAGgtaaaggcgacgccgcccatga > tgacaattaatcatcgaactagTTAACTagtacgcaagttcacgtaaaaa > ttgcgtatcggattttatcaggTACAGTgtgacgctttcgtcaatctggc > gacgctttcgtcaatctggcaaTAGATTtgcttgacattcgaccaaaatt > acattcgaccaaaattccgtcgTGCTATagcgcctgtaggccaagacctg > ggtgaaccccttctcgttatggCAAAATaagccaatacagaaccagcatt > gacagatttgtgccattccgtgAACGATcgacgcgtcgtgattaggtgaa > tttcaccagacttattcttagcTATTATagttatagagagcttacttccg > tcctgctatccaaatagtgtcaTATCATcatattaattgttcttttttca > gctgtgttattgacagttagcaTAAACTaggtgtgacgttaactatatgt > cgattccgtctctctgatgattGATGTTaattaacaatgtattcaccgaa > tgtccttgttcgataaacacaaTAAACTtgatcatgaaattgccagaaag > tatcctcgtgctgtttctcacgTAGTCTataatttcctttttaagcccac > tttgttaaaaaagtgtgtaggaTATTGTtactcgcttttaacagggcaac > ttacttcccgtaggattcttgcTTTAATagtgggattaatttccacatta > attacgcaacgataatagcgggTATAAGataaataaaaggtaaaacgttt > tttgtctcaccttttaatttgcTACCCTatccatacgcacaataaggcta > tccccttttcgtcaagatcggcCAAAATtccacgcttacactatttgcgt > attctcaacataaaaaactttgTGTAATacttgtaacgctacatggagat > ttcatccggttaaatatgcaaaGATAAAtgcgcagaaatgtgtttctcaa > gtgcattagcttatttttttgtTATCATgctaaccacccggcgaggtgtg > tgacttttatcgccgtagccttTTCAATaaaggtcttttgaagagtacca > ttaacgtttttaactttttaatTAGAATatagatacaggagagcacatat > taacggatgtatccgtttagtcTATGATatgtacagcacttttggcttcg > tcactttccgctgattcggtgcCAGACTgaaatcagcctataggaggaaa > gggcttgaaaaagcgcccaatgTATTCCaggcttatctaacacgctgata > cttaccgtcacattcttgatggTATAGTcgaaaactgcaaaagcacatga > accaactggcaaaattttgtccTAAACTtgatctcgacgaaatggctgca > catttttatcgtaattgcccttTAAAATtcggggcgccgaccccatgtgg > aaaattcggggcgccgaccccaTGTGGTctcaagcccaaaggaagagtga > ttgacgctgcgtaaggtttttgTAATTTtacaggcaaccttttattcact > ataaaataattttttcgatatcTAAAATaaatcgcgaaacgcaggggttt > ttgaaaatagtcgcgtaacccaTACGATgtgggtatcgcatattgcgttt > tttcgcaagctcgtaaaagcagTACAGTgcaccgtaagaaaattacaagt > tcttcatccttcgctggatatcTATCCAgcatttttttatcatacagcat > gacgagtacagttgcgtcgattTAGGAAaaatcttagataagtgtaaaga > cttcatgaccgtgaatagagtcCATCGTccctcctcaaaaaaagcctagc > tgacgaagcagccgttatgcctTAACCTgcgccgcagatatcactcataa > tgaaacattgatgtctctgtagCAACATaggggtaatcttactgacaaca > tgtctgaacgtgaattgcagatTATGCTgatgatcaccaagggccagaag > tcaaagttgcaataaaaaccgcTAATATacgaatgactaactatcagtag > gattaaaaaccctgcagaaacgGATAATcatgccgataactcatataacg > ctttgttgcgctcaagacgcagGATAATtagccgataagcagtagcgaca > tactttaagacaattccaggcaAATTATacaacactttacgggatagtaa > tttgtttcacatttctgtgacaTACTATcggatgtgcggtaattgtatgg > ttcacatttctgtgacatactaTCGGATgtgcggtaattgtatggaacag > ttcacatttctgtgacatactaTCGGATgtgcggtaattgtatggaacag > tgtgacatactatcggatgtgcGGTAATtgtatggaacaggagacacaca > tgtgacatactatcggatgtgcGGTAATtgtatggaacaggagacacaca > gctgattagcacggtgatatttGATACTctggcagacagcagaaataacg > taataaatagttaattaacgctCATCATtgtacaatgaactgtacaaaag > ttaaatctttgtgggatcagggCATTATcttacgtgatcagaataaacaa > ttatactttaataagtactttgTATACTtatttgcgaacattccaggccg > atataaagccacaacgggttcgTAAACTgttatcccattacatgattatg > gaagtcctgtattcagtgctgaCAAAATagccgccagcaagcagtcattt > tgataattgttatcgtttgcatTATCGTtacgccgcaatcaaaaaaggct > taacatttggattgataattgtTATCGTttgcattatcgttacgccgcaa > tggattattctgcatttttgggGAGAATggacttgccgactgattaatga > acctcaaactgcgcggctgtgtTATAATttgcgacctttgaatccgggat > tgcaagagggtcattttcacacTATCTTgcagtgaatcccaaacataccc > atttaatttatgaatgttttctTAACATcgcggcaactcaagaaacggca > aaatcacgtttcactttcgaatTATGAGcgaatatgcgcgaaatcaaaca > attagctgtataaaagaatttcTACAGTgattgtaaggttttttttattc > ccaaagtttcgggctgttatgtTTTAATgtgcaacattcatggtctgttg > acgagagttaaccggacaagtgTGCCATaatctcgcggccaggcatactt > tgttcggcgtacaagtgtacgcTATTGTgcattcgaaacttactctatgt > caacattccagctggtccgaccTATACTctcgccactggtctgatttcta > ggcgctacgctcaatgaaacatTTAAATactatacgacagcgacatttat > ttgaggaatcaggcgggagtgaTAGAATatcgcccacttaatttttccag > tgtcaacgaaaacaataatgcgTAAGGTagaaacccgaactacattgagg > tgcgcaatttgtcaacgaaaacAATAATgcgtaaggtagaaacccgaact > ttccgcatattctctgagcgggTATGCTacctgttgtatcccaatttcat > attcagcctgtcggaactggtaTTTAACcagactaattattttgatgcgc > attcagcctgtcggaactggtaTTTAACcagactaattattttgatgcgc > ggttcaattcttcctttagcggCATAATgtttaatgacgtacgaaacgtc > ttcttcctttagcggcataatgTTTAATgacgtacgaaacgtcagcggtc > tggcagttgaccgtggtaatgaTATGATttcacacctttaccagccaatg > gcttttaatgccataccaaacgTACCATtgagacacttgtttgcacagag > attgttgtatgcatgtttttttTATGCTttccttaagaacaactcacccc > cagaactcaatgcacaaggcagTATTAAcgtcgtcaattattcccaacat > ttgccgccttgaagaaaggaggTATAATccgtcgattttttttgtggctg > cgcaaacgtttgctttccctgtTAGAATtgcgccgaattttatttttcta > ccggaagctggttgcgtgaaatTAGAAAtttcgccgctgatccaaacctg > gggaagcgcctcgcttcccgtgTATGATtgaacccgcatggctcccgaaa > ttcccttcgccatttccttgagCAAACTttagctattcttatcaattatg > tgttatcgcacaatgattcggtTATACTgttcgccgttgtccaacaggac > ggaatgaattggcgttatgtgtTACGTTtagcagatcaaaagacaggcga > ggggcgcaaccggacagaatttTATAAActgctttcccgacacgagctgg > ttcgtcagcgcatcagattcttTATAATgacgcccgtttcccccccttgg > ttgtagtgtagaatgcggcgttTCTATTaatacagacgttaagctcagaa > gaataattgagggatgacctcaTTTAATctccagtagcaactttgatccg > gacagcgtgaaaacagtacgggTACTGTactaaagtcacttaaggaaaca > ttgaaaactttactttatgtgtTATCGTtacgtcatcctcgctgaggatc > ttgaaaccctgaaactgatcccCATAATaagcgaagttagcgagatgaat > ggaaatataataagtgatcgctTACACTacgcgacgaaatactttttttg > acgcaaataatttgtggtgatcTACACTgatactctgttgcattattcgc > tgcattattcgcctgaaaccacAATATTcaggcgttttttcgctatcttt > ttgcctcagattctcagtatgtTAGGGTagaaaaaagtgactatttccat > ttactttatttgtcactgtcgtTACTATatcggctgaaattaatgaggtc > taccttcccagtcaagaaaactTATCTTattcccacttttcagttaccag > ttgatactgtatgagcatacagTATAATtgcttcaacagaacatattgac > cttttaaatctttcaatctgatTAGATTaggttgccgtttggtaataaaa > gcggcagcgtggcggaaggttgTAAACTgcacctcgaagaacaagaggcc > tgcgtcgcaaccgacaattacgTATTCTgagtcttcgggtgaacagagtg > gttattttgccgcaggtcagcgTATCGTgaacatcttttccagtgttcag > tcattcgttctcttacgctcccTATAGTcgaaacatctgatggcaagaaa > taatccacaccgtttgccccgtTAACCTtaccttctcttctgttttatgg > tgtggcacaggtcatgttcgggTATACTgctttcccgtcttggttattcc > aaaacatttaccccaaaggggcTATTTTctcactcctgatttcaatagtg > tattacagagcgttttttatttGAAAATgaatccatgagttcatttcaga > ggtagaagctcaacggacaattTATAATggctcagattaaaaaaactaat > tgcgcaatctatccgcttacttTATGATgcgcaccagtcacggactgatg > acacctgcgtgagttgttcacgTATTTTttcactatgtcttactctctgc > tccttttattccacgtttcgctTATCCTagctgaagcgtttcagtcgatt > gttcgaggcaggtttgtacggtTATACTtatcttgaagatgagtaagtcc > aatttcccatacagagctaaggGATAATgcgtagcgttcacgtaactgga > tctccaaaatatattcacgttgTAAATTgtttaacgtcaaatttcccata > taacaaaaaaccagtccgcgaaGTTGATagaatcccatcatctcgcacgg > acaacagtaaaatcagagcgttTCTGCTtttactgatgtctggcggtcgg > ttacatcaacccgcattggtccTACACTgcgcggtaataaagcgaggtaa > cgcccctggagaaagcctcgtgTATACTcctcacccttataaaagtccct > tacaaagcagcagcaattgcagTAAAATtccgcaccattttgaaataagc > caccgggcaacttttagagcacTATCGTggtacaaataatgctgccaccc > aaaaactgtcgatgtgggacgaTATAGCagataagaatattgctgagcaa > gcacatatcctgttcatttcatTTTGATacacttcatgccgtcaatgagg > gtcttttgtactcgtgtactggTACAGTgcaatgcataacaacgcagtcg > tgcgataacaggtcgctacgagTAGAATactgccgcttaacgtcgcgtaa > tgcattttttacccaaaacgagTAGAATttgccacgtttcaggcgcgggg > tgacctgtatcagctttcccgaTAAGTTggaaatccgctggaagctttct > gtttctcaataacgaaatttgaTAAAATcccgctctttcataacattatt > ataaaaattcatctgtatgcacAATAATgttgtatcaaccaccatatcgg > tgattatcttccctgataagacCAGTATttagctgccaattgctacgaaa > acccatatccttgaagcggtgtTATAATgccgcgccctcgatatggggat > ttgcgttcggtggttaagtatgTATAATgcgcgggcttgtcgtagttgac > tgacaccttttcggcatcgcccTAAAATtcggcgtcctcatattgtgtga > agacacaaagcgaaagctatgcTAAAACagtcaggatgctacagtaatac > gccaaacccgctggagtattgaGATAATtttcagtctgactctcgcaata > tgacgcgcgcaggtatttagcaTACAAGgagtaccgatttgagagttggt > acacctaaaatgctatttctgcGATAATagcaaccgtttcgtgacaggaa > attgtatacttaagctgctgttTAATATgctttgtaacaatttaggctga > ggaaggtcaacatcgagcctggCAAACTagcgataacgttgtgttgaaaa > taacgccacgcttgaggtaacaGAGATTgttttacctgctggggagtggc > tttttctgtaattcgagcatgtCATGTTaccccgcgagcataaaacgcgt > tgtcatctttctgacaccttacTATCTTacaaatgtaacaaaaaagttat > ttttatgctgacaaaggcacttTTTTCTgtttatctatcaataaattcag > ttccaatatcataaaaatcgggTATGTTttagcagagtatgctgctaaag > ggtctgataaaacagtgaatgaTAACCTcgttgctcttaagctctggcac > gaacttgtggataaaatcacggTCTGATaaaacagtgaatgataacctcg > gaacttgtggataaaatcacggTCTGATaaaacagtgaatgataacctcg > cgcctgaataataaaagcgtgtTATACTctttccctgcaatgggttccgt > attgacggatcatccgggtcgcTATAAGgtaaggatggtcttaacactga > tgacttatccgcttcgaagagaGACACTacctgcaacaatcaggagcgca > tgacgttttcacattctgttgaCAGATTgtaggtcacgaggggcatttta > tgcatcacccgccaatgcgtggCTTAATgcacatcaacggtttgacgtac > gttttgtttggcttatcgctggCAAACTgtctgaaatcgcagcaataagg > ggacagttaaccgattcagtgcCAGATTtcgcagtatctacaaggtccgg > tgcggaaaaaacgcgcgcgaggCAGCATtgactttactaggtcgtgcacg > cgtcgcgacctataagtttgggTAATATgtgctggaatttgccctgtctg > atctcaggcctgatttgctgctGATTTTtacaatgcatgcctcacgcagg > ttgaaaagttcatttccagaccCATTTTtacatcgtagccgatgaggacg > agatgtttaccgtggaaaagggTAAAATaacggattaacccaagtataaa > gcatcaggacgttcgctattacTTAAATggtatgctgtttgaaaccgaag > tatgaaatttaccgtagaacgtGAGCATttattaaaaccgctacaacagg > tcagaagacggtggcggagtacTACAAGatcaaagtcgcggatctccttt > gcaggaaaaactggtcaccatcGACAATattcagaagacggtggcggagt > gcgttctttatcgccaagcgtcTACGATctaacgtacgtgagctggaagg > cccgcctcgcggcaggatcgttTACACTtagcgagttctggaaagtcctg > agacaaaaattggcttaatcgaTCTAATaaagatccaggacgatccttgc > ttgcgctttacccatcagcccgTATAATcctccacccggcgcgccatgct > tgactccggagtgtacaattatTACAATccggcctctttaatcacccatg > gttttttcaaggtgaagcggttTAAATTcgttctcaaattacagtcagga > gacaaaaggcgtgacgatggtcGAAAATggcgctttcgtcagcggggata > tggcagtctttctgcctaacgtTTTGTTtatgatatttgcctggcgtcac > ttgaaatcacgggggcgcaccgTATAATttgaccgctttttgatgcttga > gttttcccaactcagtcaggatTAAACTgtgggtcagcgaaacgtttcgc > ttatttttaaaaaacaacaattTATATTgaaattattaaacgcatcataa > ttgccagcccacggtcggtcgaCTTACTgtttagtcagttaaataaactg > ggaaatttattgcggaaattgaTATATTcacaacgtcacattgcaatttt > atatatcaatttccgcaataaaTTTCCTgtcatatagtgaattcaatctc > tcacattcaaatgcgattctgcTACAATcctccccccgttcgaagattga > ggacgcccggcgtgagtcatgcTAACTTagtgttgacttcgtattaaaca > ttacggtcaatcagcaaggtgtTAAATTgatcacgttttagaccattttt > ttggcatctctgacctcgctgaTATAATcagcaaatctgtatatataccc > gaaaaaatgttaaacccttcggTAAAGTgtctttttgcttcttctgacta > tgcatatttttaacacaaaataCACACTtcgactcatctggtacgaccag > gcgctttttatccgtaaaaagcTATAATgcactaaaatggtgcaacctgt > gcaccaacatggtgcttaatgtTTCCATtgaagcactatattggtgcaac > ggtaagaacctgacctcgtgatTACTATttcgccgtgttgacgacatcag > ttttcaatatcatttaattaacTATAATgaaccaactgcttacgcggcat > tctcgtttttgctcgttaacgaTAAGTTtacagcatgcctacaagcatcg > attgacgtccattaacacaatgTTTACTctggtgcctgacatttcaccga > tttcggttgacgcccttcggctTTTCCTtcatctttacatctggacgtct > gttgacacacctctggtcatgaTAGTATcaatattcatgcagtatttatg > tttattacgctcaacgttagtgTATTTTtattcataaatactgcatgaat > gcgctgaaacagtcaaagcggtTATGTTcatatgcggatggcgatttaca > gatagggataatcgttcattgcTATTCTacctatcgccatgaactatcgt > tggacatctgatgagcaatcccTACAATcgccgcgtactttaatttttca > gacagtaacttgttacaacctgTAGCATccacttgccggtcctgtgagtt > tgcatgaactcgcatgtctccaTAGAATgcgcgctacttgatgccgactt > gacgcaatgcgcactaaaagggCATCATttgatgccctttttgcacgctt > tgcacaaggcgtgagattggaaTACAATttcgcgccttttgtttttatgg > ttacgtgggcggtgattttgtcTACAATcttacccccacgtataatgctt > tttgactactgctgtgcctttcAATGCTtgtttctatcgacgacttaata > ttcgcgagcgttgcgcaaacgtTTTCGTtacaatgcgggcgaaaaataag > cgacattggcaaattttctggtTATCTTcagctatctggatgtctaaacg > ttgattttgcattttaaatgagTAGTCTtagttgtgctgaacgaaaagag > accacagatgcgtttatgccagTATGGTttgttgaatttttattaaatct > ttgacaaccgccccgctcacccTTTATTtataaatgtactacctgcgcta > tggaaagaggttgccgtataaaGAAACTagagtccgtttaggtgttttca > tttaagccatctcctgatgacgCATAGTcagcccatcatgaatgttgctg > tccaaaatcgccttttgctgtaTATACTcacagcataactgtatatacac > attcattcaggtcaatttgtgtCATAATtaaccgtttgtgatcgccggta > gaatgcattacccggagtgttgTGTAACaatgtctggccaggtttgtttc > ggtaatggtacaatcgcgcgttTACACTtattcagaacgatttttttcag > acctcaagttaacttgaggaatTATACTccccaacagatgaattaacgaa > ataaaatgtggcataaaagatgCATACTgtagtcgagagcgcgtatgcgt > tgatcacaaatttaaacactggTAGGGTaaaaaggtcattaactgcccaa > agtcatcctccctcactcctgcCATAATtctgatattccaggaaagagag > ctgtgatctattcagcaaaaatTTAAATaggattatcgcgagggttcaca > gtaagcgttagtttcgataagaTAAACTgagttactaatagtcgaggcag > ttgaggtaagcgttagtttcgaTAAGATaaactgagttactaatagtcga > ggattaatccttttttcgtgagTAATCTtatcgccagtttggtctggtca > cggtagaaatcctcaagcagcaTATGATctcgggtattcggtcgatgcag > ttgtcacgctgattggtgtcgtTACAATctaacgcatcgccaatgtaaat > gtcatgaatccatggcagtgacCATACTaatggtgactgccattgatgga > ttttcaaagcgtaaaattgtggCATTCTtcactgttctataagtaagacg > ggcattcacaaatgcgcaggggTAAAACgtttcctgtagcaccgtgagtt > tttcctgtagcaccgtgagttaTACTTTgtataacttaaggaggtgcaga > ttgcgccgcttctgacgatgagTATAATgccggacaatttgccgggagga > gccaccgctttcacagaagtggTAGACTtcgttccttatgaagattctct > taaggaaaataattcttatttcGATTGTcctttttacccttctcgttcga > tggaaacaattttatttccaatTGTAATgataaccattctcatattaata > ggcgtttgtatggcaacgttatTATAATtaacagttgctactccatttaa > gaacatcgatctcgtcttgtgtTAGAATtctaacatacggttgcaacaac > aagtgtgttgcggagtagatgtTAGAATactaacaaactcgcaaggtgaa > tcgccgtatcagcgaataacggTATACTgatctgatcatttaaatttgaa > ttgcttctggcaacattaagtcTCAAATtttcaaagggtggaagatggct > gccagaagcaatggatacaaggTAGCCTcatgcgttattttccctgcttc > ttactgatccgcacgtttatgaTATGCTatcgtactctttagcgagtaca " > </form>--> <!-- <hr > <a name="globins"></a> <h2>Globins</h2> <img alt="" src="examples/globins.png" ><br > The end of the B helix through the beginning of the D helix of 34 globins. This sequence data was taken from <a href="http://www.lecb.ncifcrf.gov/~toms/paper/logopaper/">Sequence Logos: A New Way to Display Consensus Sequences</a>.<br ><br > <form method="post" action="create.cgi"> <input type="submit" name="cmd_edit" value="Edit Logo" > <input type="hidden" name="logo_start" value="61" > <input type="hidden" name="logo_end" value="83" > <input type="hidden" name="show_xaxis" value="true" > <input type="hidden" name="show_yaxis" value="true" > <input type="hidden" name="show_errorbars" value="true" > <input type="hidden" name="show_fineprint" value="true" > <input type="hidden" name="scale_width" value="true" > <input type="hidden" name="sequences" value=" >Lamprey GLOBIN V - SEA LAMPREY PIVDTGSVA-P------------------LSAAEKTKIRSAWAPVYSTY---ETSGVDILVKFFTSTPAAQEFFPKFKGL TT-----ADQLKKSA---DVRWHA-ERIINAVNDAVASMDDTEKMS--MKL-RDLSGKH----AKSFQV-----DPQYFK VLAAVI-AD-TVAAGD--AGFEKLMSM------I---CILLR----S-----A-----Y------------ >Hagfish GLOBIN III - ATLANTIC HAGFISH PITDHGQPP-T------------------LSEGDKKAIRESWPQIYKNF---EQNSLAVLLEFLKKFPKAQDSFPKFSAK KS-------HLEQDP---AVKLQA-EVIINAVNHTIGLMDKEAAMK--KYL-KDLSTKH----STEFQV-----NPDMFK ELSAVF-VS-TMG-GK--AAYEKLFSI------I---ATLLR----S-----T-----YDA---------- >Frog HEMOGLOBIN BETA CHAIN - EDIBLE FROG ----------GS-----------------------DLVSGFWGKV--DA---HKIGGEALARLLVVYPWTQRYFTTFGNL GSADAIC-----HNA---KVLAHG-EKVLAAIGEGLKHPENLKAHY--AKL-SEYHSNK----LHVDPANFRLLGNVFIT VLARHF-QH-EFTPELQ-HALEAHFCA------V---GDALA----K-----A-----YH----------- >African Elephant HEMOGLOBIN BETA CHAIN - AFRICAN ELEPHANT ----------VN-----------------LTAAEKTQVTNLWGKV--NV---KELGGEALSRLLVVYPWTRRFFEHFGDL STAEAVL-----HNA---KVLAHG-EKVLTSFGEGLKHLDNLKGTF--ADL-SELHCDK----LHVDPENFRLLGNVLVI VLARHF-GK-EFTPDVQ-AAYEKVVAG------V---ANALA----H-----K-----YH----------- >Goat HEMOGLOBIN BETA-A CHAIN - GOAT ----------M------------------LTAEEKAAVTGFWGKV--KV---DEVGAEALGRLLVVYPWTQRFFEHFGDL SSADAVM-----NNA---KVKAHG-KKVLDSFSNGMKHLDDLKGTF--AQL-SELHCDK----LHVDPENFKLLGNVLVV VLARHH-GS-EFTPLLQ-AEFQKVVAG------V---ANALA----H-----R-----YH----------- >Primate HEMOGLOBIN BETA CHAIN - HUMAN, CHIMPANZEES, AND GORILLA ----------VH-----------------LTPEEKSAVTALWGKV--NV---DEVGGEALGRLLVVYPWTQRFFESFGDL STPDAVM-----GNP---KVKAHG-KKVLGAFSDGLAHLDNLKGTF--ATL-SELHCDK----LHVDPENFRLLGNVLVC VLAHHF-GK-EFTPPVQ-AAYQKVVAG------V---ANALA----H-----K-----YH----------- >Gibbon HEMOGLOBIN BETA CHAIN - COMMON GIBBON (TENTATIVE SEQUENCE) ----------VH-----------------LTPEEKSAVTALWGKV--NV---DEVGGEALGRLLVVYPWTQRFFESFGDL STPDAVM-----GNP---KVKAHG-KKVLGAFSDGLAHLDNLKGTF--AQL-SELHCDK----LHVDPENFRLLGNVLVC VLAHHF-GK-EFTPQVQ-AAYQKVVAG------V---ANALA----H-----K-----YH----------- >Dog HEMOGLOBIN BETA CHAIN - DOG AND COYOTE ----------VH-----------------LTAEEKSLVSGLWGKV--NV---DEVGGEALGRLLIVYPWTQRFFDSFGDL STPDAVM-----SNA---KVKAHG-KKVLNSFSDGLKNLDNLKGTF--AKL-SELHCDK----LHVDPENFKLLGNVLVC VLAHHF-GK-EFTPQVQ-AAYQKVVAG------V---ANALA----H-----K-----YH----------- >Horse HEMOGLOBIN BETA CHAIN - HORSE ----------VQ-----------------LSGEEKAAVLALWDKV--NE---EEVGGEALGRLLVVYPWTQRFFDSFGDL SNPGAVM-----GNP---KVKAHG-KKVLHSFGEGVHHLDNLKGTF--AAL-SELHCDK----LHVDPENFRLLGNVLVV VLARHF-GK-DFTPELQ-ASYQKVVAG------V---ANALA----H-----K-----YH----------- >Human, Chimp HEMOGLOBIN GAMMA CHAINS - HUMAN AND CHIMPANZEE ----------GH-----------------FTEEDKATITSLWGKV--NV---EDAGGETLGRLLVVYPWTQRFFDSFGNL SSASAIM-----GNP---KVKAHG-KKVLTSLGDAIKHLDDLKGTF--AQL-SELHCDK----LHVDPENFKLLGNVLVT VLAIHF-GK-EFTPEVQ-ASWQKMVTA------V---ASALS----S-----R-----YH----------- >Nile Crocodile HEMOGLOBIN BETA CHAIN - NILE CROCODILE ----------AS-----------------FDPHEKQLIGDLWHKV--DV---AHCGGEALSRMLIVYPWKRRYFENFGDI SNAQAIM-----HNE---KVQAHG-KKVLASFGEAVCHLDGIRAHF--ANL-SKLHCEK----LHVDPENFKLLGDIIII VLAAHY-PK-DFGLECH-AAYQKLVRQ------V---AAALA----A-----E-----YH----------- >Chicken HEMOGLOBIN BETA CHAIN - CHICKEN ----------VH-----------------WTAEEKQLITGLWGKV--NV---AECGAEALARLLIVYPWTQRFFASFGNL SSPTAIL-----GNP---MVRAHG-KKVLTSFGDAVKNLDNIKNTF--SQL-SELHCDK----LHVDPENFRLLGDILII VLAAHF-SK-DFTPECQ-AAWQKLVRV------V---AHALA----R-----K-----YH----------- >NA Opossum HEMOGLOBIN BETA CHAIN - NORTH AMERICAN OPOSSUM ----------VH-----------------LTSEEKNCITTIWSKV--QV---DQTGGEALGRMLVVYPWTTRFFGSFGDL SSPGAVM-----SNS---KVQAHG-AKVLTSFGEAVKHLDDLKGTY--AKL-SELHCDK----LHVDPENFKMLG-IIVI CLAEHF-GK-DFTPECV-A--WKLVAG------V---AHALA----H-----K-----YH----------- >Carp HEMOGLOBIN BETA CHAINS - CARP ----------VE-----------------WTDAERSAIIALWGKL--NP---DELGPEALARCLIVYPWTQRFFASYGNL SSPAAIM-----GNP---KVAAHG-RTVEGGLMRAIKDMDNIKATY--APL-SVMHSEK----LHVDPDNFRLLADCITV CAAMKFGPS-GFSPNVQ-EAWQKFLSV------V---VNALK----R-----Q-----YH----------- >Shark HEMOGLOBIN BETA CHAIN - PORT JACKSON SHARK ----------VH-----------------WSEVELHEITTTWKSI--DK---HSLGAKALARMFIVYPWTTRYFGNLKEF TA----------CSY---GVKEHA-KKVTGALGVAVTHLGDVKSQF--TDL-SKKHAEE----LHVDVESFKLLAKCFVV ELGILL-KD-KFAPQTQ-AIWEKYFGV------V---VDAIS----K-----E-----YH----------- >Shark HEMOGLOBIN ALPHA CHAIN - PORT JACKSON SHARK ----------S-TSTSTSD----------YSAADRAELAALSKVLAQNA---EAFGAEALARMFTVYAATKSYFKDYKDF TA----------AAP---SIKAHG-AKVVTALAKACDHLDDLKTHL--HKL-ATFHGSE----LKVDPANFQYLSYCLEV ALAVHL--T-EFSPETH-CALDKFLTN------V---CHELS----S-----R-----YR----------- >Carp HEMOGLOBIN ALPHA CHAIN - CARP ----------S------------------LSDKDKAAVKIAWAKISPKA---DDIGAEALGRMLTVYPQTKTYFAHWADL SP----------GSG---PVKHGK-KVIMGAVGDAVSKIDDLVGGL--ASL-SELHASK----LRVDPANFKILANHIVV GIMFYL-PG-DFPPEVH-MSVDKFFQN------L---ALALS----E-----K-----YR----------- >Bullfrog HEMOGLOBIN ALPHA CHAIN - BULLFROG TADPOLE ----------S------------------LSASEKAAVLSIVGKIGSQG---SALGSEALTRLFLSFPQTKTYFPHF-DL TP----------GSA---DLNTHG-GKIINALAGAANHLDDLAGNL--SSL-SDLHAYN----LRVDPGNFPLLAHIIQV VLATHF-PG-DFTAEVQ-AAWDKFLAL------V---SAVLT----S-----K-----YR----------- >Nile Crocodile HEMOGLOBIN ALPHA CHAIN - NILE CROCODILE ----------V------------------LSSDDKCNVKAVWSKVAGHL---EEYGAEALERMFCAYPQTKIYFPHF-DL SH----------GSA---QIRAHG-KKVFAALHEAVNHIDDLPGAL--CRL-SELHAHS----LRVDPVNFKFLAQCVLV VVAIHH-PG-SLTPEVH-ASLDKFLCA------V---SSVLT----S-----K-----YR----------- >Ostrich HEMOGLOBIN ALPHA CHAIN - OSTRICH ----------V------------------LSGTDKTNVKGIFSKISSHA---EEYGAETLERMFITYPQTKTYFPHF-DL HH----------GSA---QIKAHG-KKVANALIEAVNHIDDISGAL--SKL-SDLHAQK----LRVDPVNFKLLGQCFLV VVAIHH-PS-ALTPEVH-ASLDKFLCA------V---GAVLT----A-----K-----YR----------- >Kangaroo HEMOGLOBIN ALPHA CHAIN - EASTERN GRAY KANGAROO ----------V------------------LSAADKGHVKAIWGKVGGHA---GEYAAEGLERTFHSFPTTKTYFPHF-DL SH----------GSA---QIQAHG-KKIADALGQAVEHIDDLPGTL--SKL-SDLHAHK----LRVDPVNFKLLSHCLLV TFAAHL-GD-AFTPEVH-ASLDKFLAA------V---STVLT----S-----K-----YR----------- >Armadillo HEMOGLOBIN ALPHA CHAIN - NINE-BANDED ARMADILLO ----------V------------------LSAADKTHVKAFWGKVGGHA---AEFGAEALERMFASFPPTKTYFSHM-DL SH----------GSA---QVKAHG-KKVADALTLAVGHLDDLPGAL--STL-SDLHAHK----LRVDPVNFKFLSHCLLV TLACHL-PD-DFTPAVH-ASMDKFMAG------V---STVLV----S-----K-----YR----------- >Horse HEMOGLOBIN ALPHA CHAINS - HORSE ----------V------------------LSAADKTNVKAAWSKVGGHA---GEYGAEALERMFLGFPTTKTYFPHF-DL SH----------GSA---QVKAHG-KKVGDALTLAVGHLDDLPGAL--SNL-SDLHAHK----LRVDPVNFKLLSHCLLS TLAVHL-PN-DFTPAVH-ASLDKFLSS------V---STVLT----S-----K-----YR----------- >Primate HEMOGLOBIN ALPHA CHAIN - HUMAN AND CHIMPANZEES ----------V------------------LSPADKTNVKAAWGKVGAHA---GEYGAEALERMFLSFPTTKTYFPHF-DL SH----------GSA---QVKGHG-KKVADALTNAVAHVDDMPNAL--SAL-SDLHAHK----LRVDPVNFKLLSHCLLV TLAAHL-PA-EFTPAVH-ASLDKFLAS------V---STVLT----S-----K-----YR----------- >Macaque HEMOGLOBIN ALPHA CHAIN - RHESUS MACAQUE AND JAPANESE MACAQUE ----------V------------------LSPADKSNVKAAWGKVGGHA---GEYGAEALERMFLSFPTTKTYFPHF-DL SH----------GSA---QVKGHG-KKVADALTLAVGHVDDMPNAL--SAL-SDLHAHK----LRVDPVNFKLLSHCLLV TLAAHL-PA-EFTPAVH-ASLDKFLAS------V---STVLT----S-----K-----YR----------- >Badger HEMOGLOBIN ALPHA CHAIN - EURASIAN BADGER ----------V------------------LSPADKANIKATWDKIGGHA---GEYGGEALERTFASFPTTKTYFPHF-DL SH----------GSA---QVKGHG-KKVADALTNAVAHLDDLPGAL--SAL-SDLHAYK----LRVDPVNFKLLSHCLLV TLACHH-PA-EFTPAVH-ASLDKFLSS------V---STVLT----S-----K-----YR----------- >Ind Elephant HEMOGLOBIN ALPHA CHAIN - INDIAN ELEPHANT ----------V------------------LSDKDKTNVKATWSKVGDHA---SDYVAEALERMFFSFPTTKTYFPHF-DL SH----------GSG---QVKGHG-KKVGEALTQAVGHLDDLPSAL--SAL-SDLHAHK----LRVDPVNFKLLSHCLLV TLSSHQ-PT-EFTPEVH-ASLDKFLSN------V---STVLT----S-----K-----YR----------- >Hyrax HEMOGLOBIN ALPHA CHAIN - ABYSSINIAN HYRAX ----------V------------------LSAADKNNVKGAWEKVGTHA---GEYGAEALERMFLSFPTTKTYFPHF-DL TH----------GSA---QVKAHG-QKVGAALTKAVGHLDDLPNAL--SDL-SDLHAHK----LRVDPVNFKLLSHCLLV TLSRHL-PEQEFTPAVH-ASLDKFFSN------V---STVLT----S-----K-----YR----------- >Tuna MYOGLOBIN - YELLOWFIN TUNA ----------A----------------------DFDAVLKCWGPVEADY---TTMGGLVLTRLFKEHPETQKLFPKFAGI -A-----QADIAGNA---AISAHG-ATVLKKLGELLKAKGSHAAIL--KPL-ANSHATK----HKIPINNFKLISEVLVK VMHEK---A-GLDAGGQ-TALRNVMGI------I---IADLE----ANYKELG-----FSG---------- >Shark MYOGLOBIN - PORT JACKSON SHARK ----------T----------------------EWEHVNKVWAVVEPDI---PAVGLAILLRLFKEHKETKDLFPKFKEI -P-----VQQLGNNE---DLRKHG-VTVLRALGNILKQKGKHSTNV--KEL-ADTHINK----HKIPPKNFVLITNIAVK VLTEMY-PS-DMTGPMQ-ESFSKVFTV------I---CSDLE----TLYKEAN-----FQG---------- >Turtle MYOGLOBIN - MAP TURTLE ----------G------------------LSDDEWHHVLGIWAKVEPDL---SAHGQEVIIRLFQVHPETQERFAKFKNL KT-----IDELRSSE---EVKKHG-TTVLTALGRILKLKNNHEPEL--KPL-AESHATK----HKIPVKYLEFICEIIVK VIAEKH-PS-DFGADSQ-AAMRKALEL------F---RNDMA----SKYKEFG-----FQG---------- >Chicken MYOGLOBIN - CHICKEN ----------G------------------LSDQEWQQVLTIWGKVEADI---AGHGHEVLMRLFHDHPETLDRFDKFKGL KT-----EPDMKGSE---DLKKHG-QTVLTALGAQLKKKGHHEADL--KPL-AQTHATK----HKIPVKYLEFISEVIIK VIAEKH-AA-DFGADSQ-AAMKKALEL------F---RDDMA----SKYKEFG-----FQG---------- >Dog MYOGLOBIN - DOG, BAT-EARED FOX, AFRICAN HUNTING DOG, AND CAPE FOX ----------G------------------LSDGEWQIVLNIWGKVETDL---AGHGQEVLIRLFKNHPETLDKFDKFKHL KT-----EDEMKGSE---DLKKHG-NTVLTALGGILKKKGHHEAEL--KPL-AQSHATK----HKIPVKYLEFISDAIIQ VLQSKH-SG-DFHADTE-AAMKKALEL------F---RNDIA----AKYKELG-----FQG---------- >Badger MYOGLOBIN - EURASIAN BADGER ----------G------------------LSDGEWQLVLNVWGKVEADL---AGHGQEVLIRLFKGHPETLEKFDKFKHL KS-----EDEMKGSE---DLKKHG-NTVLTALGGILKKKGHQEAEL--KPL-AQSHATK----HKIPVKYLEFISDAIAQ VLQSKH-PG-NFAAEAQ-GAMKKALEL------F---RNDIA----AKYKELG-----FQG---------- >Dolphin MYOGLOBIN - SADDLEBACK DOLPHIN ----------G------------------LSDGEWQLVLNVWGKVEADV---AGHGQDILIRLFKGHPETLEKFDKFKHL KT-----EADMKASE---DLKKHG-DTVLTALGAILKKKGHHDAEL--KPL-AQSHATK----HKIPIKYLEFISEAIIH VLHSRH-PA-QFGADAQ-GAMNKALEL------F---RKDIA----AKYKELG-----FHG---------- >Horse, Zebra MYOGLOBIN - HORSE AND PLAINS ZEBRA ----------G------------------LSDGEWQQVLNVWGKVEADI---AGHGQEVLIRLFTGHPETLEKFDKFKHL KT-----EAEMKASE---DLKKHG-TVVLTALGGILKKKGHHEAEL--KPL-AQSHATK----HKIPIKYLEFISDAIIH VLHSKH-PG-NFGADAQ-GAMTKALEL------F---RNDIA----AKYKELG-----FQG---------- >African Elephant MYOGLOBIN - AFRICAN ELEPHANT ----------G------------------LSDGEWELVLKTWGKVEADI---PGHGEFVLVRLFTGHPETLEKFDKFKHL KT-----EGEMKASE---DLKKQG-VTVLTALGGILKKKGHHEAEI--QPL-AQSHATK----HKIPIKYLEFISDAIIH VLQSKH-PA-EFGADAQ-AAMKKALEL------F---RNDIA----AKYKELG-----FQG---------- >Aardvark MYOGLOBIN - AARDVARK ----------G------------------LSDAEWQLVLNVWGKVEADI---PGHGQDVLIRLFKGHPETLEKFDRFKHL KT-----EDEMKASE---DLKKHG-TTVLTALGGILKKKGQHEAEI--QPL-AQSHATK----HKIPVKYLEFISEAIIQ VIQSKH-SG-DFGADAQ-GAMSKALEL------F---RNDIA----AKYKELG-----FQG---------- >Human MYOGLOBIN - HUMAN ----------G------------------LSDGEWQLVLNVWGKVEADI---PGHGQEVLIRLFKGHPETLEKFDKFKHL KS-----EDEMKASE---DLKKHG-ATVLTALGGILKKKGHHEAEI--KPL-AQSHATK----HKIPVKYLEFISECIIQ VLQSKH-PG-DFGADAQ-GAMNKALEL------F---RKDMA----SNYKELG-----FQG---------- >Macaque MYOGLOBIN - CRAB-EATING MACAQUE (TENTATIVE SEQUENCE) ----------G------------------LSDGEWQLVLNVWGKVEADI---PSHGQEVLIRLFKGHPETLEKFDKFKHL KS-----EDEMKASE---DLKKHG-VTVLTALGGILKKKGHHEAEI--KPL-AQSHATK----HKIPVKYLELISESIIQ VLQSKH-PG-DFGADAQ-GAMNKALEL------F---RNDMA----AKYKELG-----FQG---------- >NA Opossum MYOGLOBIN - NORTH AMERICAN OPOSSUM ----------G------------------LSDGEWQLVLNAWGKVEADI---PGHGQEVLIRLFKGHPETLEKFDKFKHL KS-----EDEMKASE---DLKKHG-ATVLTALGNILKKKGNHEAEL--KPL-AQSHATK----HKISVQFLEFISEAIIQ VIQSKH-PG-DFGGDAQ-AAMGKALEL------F---RNDMA----AKYKELG-----FQG---------- >Earthworm GLOBIN AIII - COMMON EARTHWORM ---------KK------------------QCGVLEGLKVKSEWGRAYGS---GHDREAFSQAIWRATFAQVPESRSLFKR VH-----GDH-TSDP---AFIAHA-ERVLGGLDIAISTLDQPATLK--EEL-DHLQVQHEG--RKIPDNYFDAFKTAILH VVAAQL-GE-RCYSNN--EEIHDAIACDGFARVL---PQVLE----R-----G-----IKGHH-------- > SMALL CHAIN - TYLORRHYNCHUS HETEROCHAETUS ----------T------------------DCGILQRIKVKQQWAQVYSV---GESRTDFAIDVFNNFFRTNPD-RSLFNR VN-----GDN-VYSP---EFKAHM-VRVFAGFDILISVLDDKPVLD--QAL-AHYAAFH----KQFGTIPFKAFGQTMFQ TIAEHI--------HG--ADIGAWRAC------Y---AEQIV----T-----G-----ITA---------- >BloodwormGLOBIN, MAJOR MONOMERIC COMPONENT - BLOODWORM ----------G------------------LSAAQRQVIAATWKDIAGND---NGAGVGKDCLI--KHLSAHPQMAAVFGF SG-----ASD-PAVA---DLGAKV-LAIGVAVSHLGDGKMVAQMKA--VGV-RHKGYGN----KHIKGQYFEPLGASLLS AMEHRI-GG-KMNAAA-KDAWAAAYAD------I---SGALI----S-----G-----LQS---------- >Whelk GLOBIN - WHELK ----------G------------------LDGAQKTALKESWKVLGADGPTMMKNGSLLFGLLFKTYPDTKKHFKHFDDA TF-----AAM-DTTG---VGKAHG-VAVFSGLGSMICSIDDDDCV---GLA-KKLSRNH--LARGVSAADF-KLLEAVFK FLDEAT-QR-KATDAQ-KDADGALLTM------L---IKA------------H-----V------------ >Snail GLOBIN - WATER SNAIL ----------S------------------LQPASKSALASSWKTLAKDAATIQNNGATLFSLLFKQFPDTRNYFTHFGNM SD-----AEM-KTTG---VGKAHS-MAVFAGIGSMIDSMDDADCMN--GLA-LKLSRNH--IQRKIGASRFGEMRQVFPN FLDEAL-GG-GASGDV-KGAWDALLAY------LQDNKQA------------Q-----A----L------- >Clam GLOBIN I - BLOOD CLAM ----------P--------SVQGAAAQ--LTADVKKDLRDSWKVIGSDK---KGNGVALMTTLFADNQETIGYFKRLGNV SQ-----GM---AND---KLRGHS-ITLMYALQNFIDQLDNTDDLV--CVV-EKFAVNH--ITRKISAAEFGKINGP--- -IKKVL-AS-KNFGDK-YANAWAKLVA------V---VQA------------A-----L------------ >Midge larvaGLOBIN CTT-II BETA - MIDGE LARVA ----------A------------------PLSADEASLV---RGSWAQV---KHSEVDILYYIFKANPDIMAKFPQFAGK DL-----ETL-KGTGQFATHAGRI-VGFVSEIVALMGNSANMPAME--TLI-KDMAANH--KARGIPKAQFNEFRASLVS YLQSKV----SWNDSL-GAAWTQGLDN------V---FNMMF----S-----Y-----L------------ >Midge larva GLOBINS CTT-I AND CTT-IA - MIDGE LARVA ----------G------------------P-SGDQIAAA---KASWNTV---KNNQVDILYAVFKANPDIQTAFSQFAGK DL-----DSI-KGTPDFSKHAGRV-VGLFSEVMDLLGNDANTPTIL--AKA-KDFGKSH--KSRASP-AQLDNFRKSLVV YLKGAT----KWDSAV-ESSWAPVLDF------V---FSTLK----N-----E-----L------------ >Bacteria BACTERIAL HEMOGLOBIN - VITREOSCILLA SP -----------------------------MLDQQTINII---KATVPVL---KEHGVTITTTFYKNLFAKHPEVRPLFDM GR-----Q---ESLEQ-------P-KALAMTVLAAAQNIENLPAIL--PAV-KKIAVKH--CQAGVAAAHYPIVGQELLG AIKEVL-GD-AATDDI-LDAWGKAYGV------I---ADVFI----Q-----VEADLYA-----Q-AVE-- >P andersonii ONLEGUME HEMOGLOBIN I - PARASPONIA ANDERSONII ----------V----------------NKVFTEEQEALV---VKAWAVM---KKNSAELGLQFLK-IFEIAPSAKNLFSY LK-----DSP-VPLEQNPKLKPHA-TTFVMTTESAVQLRKAGKVTVK-ESDLKRIGAIH--FKTGVVNEHFEVTRFALLE TIKEAV-PE-MWSPEM-KNAWGVAYDQ------L---VAAIK----F-----E-----M-----KPSST-- >Yellow Lupin LEGHEMOGLOBIN I - YELLOW LUPIN ----------G------------------VLTDVQVALV---KSSFEEF---NANIPKNTHRFFTLVLEIAPGAKDLFSF LK-----GSS-EVPQNNPDLQAHAGKVFKLTYEAAIQLEVNGAVAS--DATLKSLGSVH--VSKGVVDAHFPVVKEAILK TIKEVV-GD-KWSEEL-NTAWTIAYDE------L---AIIIK----K-----E-----M-----K-DAA-- >Garden Pea LEGHEMOGLOBIN I - GARDEN PEA ----------G-------------------FTDKQEALV---NSSSE-F---KQNLPGYSILFYTIVLEKAPAAKGLFSF LK-----DTA-GVE-DSPKLQAHAEQVFGLVRDSAAQLRTKGEVVL-GNATL---GAIH--VQKGVTNPHFVVVKEALLQ TIKKAS-GN-NWSEEL-NTAWEVAYDG------L---ATAIKKAMKT---------------------A-- >Broad Bean LEGHEMOGLOBIN I - BROAD BEAN ----------G-------------------FTEKQEALV---NSSSQLF---KQNPSNYSVLFYTIILQKAPTAKAMFSF LK-----DSA-GVV-DSPKLGAHAEKVFGMVRDSAVQLRATGEVVL--DGKD---GSIH--IQKGVLDPHFVVVKEALLK TIKEAS-GD-KWSEEL-SAAWEVAYDG------L---ATAIK----A---------------------A-- >Soybean LEGHEMOGLOBIN C1 - SOYBEAN ----------G------------------AFTEKQEALV---SSSFEAF---KANIPQYSVVFYNSILEKAPAAKDLFSF LA-----NGV-DPT--NPKLTGHAEKLFALVRDSAGQLKTNGTVVA--DAAL---VSIH--AQKAVTDPQFVVVKEALLK TIKEAV-GG-NWSDEL-SSAWEVAYDE------L---AAAIK----K---------------------A-- >Kidney Bean LEGHEMOGLOBIN A - KIDNEY BEAN ----------G------------------AFTEKQEALV---NSSWEAF---KGNIPQYSVVFYTSILEKAPAAKNLFSF LA-----NGV-DPT--NPKLTAHAESLFGLVRDSAAQLRANGAVVA--DAAL---GSIH--SQKGVSNDQFLVVKEALLK TLKQAV-GD-KWTDQL-STALELAYDE------L---AAAIK----K---------------------AYA " > </form> <br > <br >--> <!-- <hr > <a name="HTH"></a> <h2>HTH Proteins</h2> <img alt="" src="examples/hth.png" > <br > Helix-Turn-Helix DNA binding motifs found by the Gibbs sampling system. Compared to the <a href="#CAP_HTH">CAP HTH logo</a> there is much less sequence conservation within the DNA binding helix (11-17), as might be expected for a diverse sample of proteins. <form method="post" action="create.cgi"> <input type="submit" name="cmd_edit" value="Edit Logo" > <input type="hidden" name="logo_title" value ="Helix-Turn-Helix Motifs" > <input type="hidden" name="first_index" value ="-11" > <input type="hidden" name="logo_start" value ="1" > <input type="hidden" name="logo_end" value ="17" > <input type="hidden" name="yaxis_scale" value ="2.0" > <input type="hidden" name="show_xaxis" value="true" > <input type="hidden" name="show_yaxis" value="true" > <input type="hidden" name="show_errorbars" value="true" > <input type="hidden" name="show_fineprint" value="true" > <input type="hidden" name="scale_width" value="true" > <input type="hidden" name="sequences" value=">A25944 DNA-directed RNA polymerase sigma-37 chain - Bacillu 223-240 iidltyiqnk SQKETGDILGISQMHVSR lqrkavkklr >A28627 spoIIIC protein - Bacillus subtilis 94-111 rfgldlkkek TQREIAKELGISRSYVSR iekralmkmf >A32837 *Transcriptional activator nahR - Pseudomonas putida 22-39 vvfnqllvdr RVSITAENLGLTQPAVSN alkrlrtslq >A23450 Antennapedia homeotic protein - Fruit fly (Drosophil 326-343 fhfnryltrr RRIEIAHALCLTERQIKI wfqnrrmkwk >B26499 Regulatory protein ntrC - Bradyrhizobium sp. 449-466 ltaalaatrg NQIRAADLLGLNRNTLRK kirdldiqvy >BVECDA dicA protein - Escherichia coli | 1551.0 1.0 1.0 1.0 22-39 iryrrknlkh TQRSLAKALKISHVSVSQ wergdseptg >C29010 Mercuric resistance operon regulatory merD protein - 5-22 ------mnay TVSRLALDAGVSVHIVRD yllrgllrpv >DNECFS DNA-binding protein fis - Escherichia coli | 928.0 1 73-90 ldmvmqytrg NQTRAALMMGINRGTLRK klkkygmn-- >JEBY1 Mating hormone a1 - Yeast (Saccharomyces cerevisiae) 99-116 frrkqslnsk EKEEVAKKCGITPLQVRV wfinkrmrsk >QCBP2L Regulatory protein cII - Phage lambda | 1559.0 2.0 1 25-42 sallnkiaml GTEKTAEAVGVDKSQISR wkrdwipkfs >QRECC cAMP receptor protein (CAP) - Escherichia coli | 1507 169-186 thpdgmqiki TRQEIGQIVGCSRETVGR ilkmledqnl >RCBPL Regulatory protein cro - Phage lambda | 1555.0 1.0 1. 15-32 itlkdyamrf GQTKTAKDLGVYQSAINK aihagrkifl >RGBP22 Regulatory protein cro - Phage P22 | 1556.0 1.0 1.0 12-29 ykkdvidhfg TQRAVAKALGISDAAVSQ wkevipekda >RGECA Arabinose operon regulatory protein - Escherichia col 196-213 isdhladsnf DIASVAQHVCLSPSRLSH lfrqqlgisv >RGECF Regulatory protein fnr - Escherichia coli | 1507.0 1. 196-213 fsprefrltm TRGDIGNYLGLTVETISR llgrfqksgm >RGECH Heat shock regulatory protein - Escherichia coli | 30 252-269 arwldednks TLQELADRYGVSAERVRQ leknamkklr >RGKBCP Nitrogen assimilation regulatory protein - Klebsiell 444-461 lttalrhtqg HKQEAARLLGWGRNTLTR klkelgme-- >RPECCT cyt repressor - Escherichia coli | 1291.0 3.0 1.0 1. 11-28 mkakkqetaa TMKDVALKAKVSTATVSR almnpdkvsq >RPECDO Deo operon repressor - Escherichia coli | 1536.0 1.0 23-40 lqelkrsdkl HLKDAAALLGVSEMTIRR dlnnhsapvv >RPECG gal repressor - Escherichia coli | 1291.0 4.0 1.0 1.0 3-20 --------ma TIKDVARLAGVSVATVSR vinnspkase >RPECL lac repressor - Escherichia coli | 1291.0 2.0 1.0 1.0 5-22 ------mkpv TLYDVAEYAGVSYQTVSR vvnqashvsa >RPECTN TetR repressor - Escherichia coli transposon Tn10 | 26-43 llnevgiegl TTRKLAQKLGVEQPTLYW hvknkralld >RPECW trp repressor - Escherichia coli | 1534.0 1.0 1.0 1.0 67-84 iveellrgem SQRELKNELGAGIATITR gsnslkaapv >S02513 Regulatory protein nifA - Klebsiella pneumoniae 495-512 liaalekagw VQAKAARLLGMTPRQVAY riqimditmp >S07337 *spoIIG protein - Bacillus subtilis 205-222 rfglvgeeek TQKDVADMMGISQSYISR lekriikrlr >S07958 *DNA-invertase - Escherichia coli 160-177 qagrliaagt PRQKVAIIYDVGVSTLYK tfpagdk--- >S08477 Regulatory protein purR - Escherichia coli 3-20 -------ma TIKDVAKRANVSTTTVSH vinktrfvae- >S09205 *ebgR protein - Escherichia coli 3-20 --------ma TLKDIAIEAGVSLATVSR vlnddptlnv >S11945 *lexA repressor - Escherichia coli 27-44 dhisqtgmpp TRAEIAQRLGFRSPNAAE ehlkalarkg >Z1BPC2 Regulatory protein cI - Phage P22 | 1559.0 1.0 1.0 1 25-42 ssilnriair GQRKVADALGINESQISR wkgdfipkmg " > </form> <br ><br > <hr > <a name="splice"></a> <h2>Human Splice Sites</h2> <img alt="" src="examples/exon-intron.png" ><img alt="" src="examples/intron-exon.png" > <br > <br > These logos show a small sample of Human intron-exon splice boundaries. Sequences of experimentally confirmed genes were extracted from <a href="http://mcb.harvard.edu/gilbert/EID/">EID: the Exon-Intron database</a>. Additional discussion of the features in this logo can be found in the paper <a href="http://www.lecb.ncifcrf.gov/~toms/paper/splice/"> Features of spliceosome evolution...</a>--> <!-- <form method="post" action="create.cgi"> <input type="submit" name="cmd_edit" value="Edit Logo" > Exon-Intron (Donor) Sites <input type="hidden" name="logo_title" value="exon | intron" > <input type="hidden" name="first_index" value="-11" > <input type="hidden" name="logo_start" value="-6" > <input type="hidden" name="logo_end" value="8" > <input type="hidden" name="show_xaxis" value="true" > <input type="hidden" name="show_yaxis" value="true" > <input type="hidden" name="show_errorbars" value="true" > <input type="hidden" name="show_fineprint" value="true" > <input type="hidden" name="scale_width" value="true" > <input type="hidden" name="sequences" value=" > 19082_AF115399 GGATCGACCCTgtaagtttt > 45328_AB000381 GCGCGCTCAGTgtaagtatc > 45328_AB000381 AATCTCCATTCgtaagtacc > 45330_AB001517 ACTGGACGCTGgtaaggact > 45331_AB001517 TCGCTTACCGGgtgagcgcg > 45331_AB001517 GACCTTAAAAAgtaagtatg > 45331_AB001517 CGTCGATGAAGgtacttgcc > 45331_AB001517 CCTGATGGCAGgtaaggggg > 45331_AB001517 GATGACTCCAGgtgcggcct > 45331_AB001517 ACAGCCTGGACgtatgtccc > 45331_AB001517 CGGCTGGCCAAgtaggtctc > 45331_AB001517 CACTCCCTGAGgtaagcctt > 45331_AB001517 TGGCTGTTCAGgtttgtccc > 45331_AB001517 ACGACGGCAAGgtaggctcc > 45331_AB001517 GACCTTCACAGgtgatgttt > 45331_AB001517 GGCTCCTTGATgtaagcacc > 45331_AB001517 GACCTCTGATGgtgagcacg > 45331_AB001517 GCCAAGGGGAAgtgagtgtc > 45331_AB001517 ACGCCATGGAGgtgagccgc > 45331_AB001517 CGTCAGGAAAGgtgagcaga > 45331_AB001517 CTCTCCCACTGgtgagcact > 45331_AB001517 CAGGGGCGAGAgtgagttgg > 45331_AB001517 CTGAAGTCCAGgtagagggt > 45331_AB001517 CTGTCGAAACTgtacgtgtg > 45332_AB001517 GGGTCGCGCTGgtgagtgga > 45332_AB001517 GAGGCCTCGGCgtaagtcct > 45332_AB001517 GGCGAGAGCAGgtgtggggg > 45332_AB001517 GCTAAAAACCTgtgcgtatt > 45332_AB001517 AAGCCCATCGGgtgtgtaca > 45333_AB001517 GGGTCGCGCTGgtgagtgga > 45333_AB001517 GAGGCCTCGGCgtaagtcct > 45333_AB001517 GGCGAGAGCAGgtgtggggg > 45333_AB001517 GCTAAAAACCTgtgcgtatt > 45334_AB001523 CATCGTCACCTgtgagtgcc > 45334_AB001523 GAATGGAGAAGgtatgagtt > 45334_AB001523 CAGAGTGCTGTgtgagtacc > 45334_AB001523 CAGAGTGACAGgtaagtgta > 45334_AB001523 TCATGGTTCAGgtacttgac > 45334_AB001523 CGGGGCCGGGGgtgagtagt > 45334_AB001523 AGCTCTTAGAAgtgagtcgg > 45334_AB001523 CCACAGAAAAGgtgcctacc > 45334_AB001523 ACCAGAAACAGgtacttttt > 45334_AB001523 AACACTACTTAgtaagtatt > 45334_AB001523 GAGTTTTACATgtaattgat > 45334_AB001523 CAAATTGAAAAgtatccttt > 45334_AB001523 AGACAGCCCAGgtaagacca > 45334_AB001523 TCAGGACTCAGgtatgcgtt > 45334_AB001523 GCCGCTGGCTGgtgagtggg > 45334_AB001523 CAACACGAGAGgtgaggtgc > 45334_AB001523 CAGACCACAAAgtgagtagg > 45334_AB001523 TCAGGAACACGgtaacggag > 45334_AB001523 AGTCCCAGCAGgtaaacatt > 45334_AB001523 AAAATTTTTTTgtaagtgat > 45334_AB001523 TATGTATGAAGgtaggtggt > 45334_AB001523 ACTGGACGCTGgtaaggact > 45335_AB001523 TCGCTTACCGGgtgagcgcg > 45337_AB00189S TGTGGTACCTGgtgagtagg > 45337_AB00189S CCCCAAATTATgtaagtcaa > 45337_AB00189S AATGAAAATAAgtacgtcac > 45338_AB00189S TGTGGTACCTGgtgagtagg > 45338_AB00189S CCCCAAATTATgtaagtcaa > 45338_AB00189S AATGAAAATAAgtacgtcac > 45338_AB00189S GGAGAAGCAAGgtcagtggc > 45339_AB00189S TGTGGTACCTGgtgagtagg > 45339_AB00189S CCCCAAATTATgtaagtcaa > 45339_AB00189S AATGAAAATAAgtacgtcac > 45339_AB00189S GGAGAAGCAAGgtcagtggc > 45340_AB00189S TGTGGTACCTGgtgagtagg > 45340_AB00189S CCCCAAATTATgtaagtcaa > 45340_AB00189S AATGAAAATAAgtacgtcac > 45341_AB00189S TGTGGTACCTGgtgagtagg > 45341_AB00189S CCCCAAATTATgtaagtcaa > 45341_AB00189S AATGAAAATAAgtacgtcac > 45341_AB00189S AAGACCAGCAGgtaatgcat > 45342_AB00189S TGTGGTACCTGgtgagtagg > 45342_AB00189S CCCCAAATTATgtaagtcaa > 45342_AB00189S AATGAAAATAAgtacgtcac > 45342_AB00189S AGATTACACAGgtaatgagc > 45342_AB00189S AAGACCAGCAGgtaatgcat > 45342_AB00189S GTGTGTCGAAGgtacggtcc > 45342_AB00189S GTGCAGCAACGgtgagcagc > 45343_AB00189S TGTGGTACCTGgtgagtagg > 45343_AB00189S CCCCAAATTATgtaagtcaa > 45343_AB00189S AATGAAAATAAgtacgtcac > 45343_AB00189S AAGACCAGCAGgtaatgcat > 45343_AB00189S GTGTGTCGAAGgtacggtcc > 45343_AB00189S GTGCAGCAACGgtgagcagc > 45344_AB00189S TGTGGTACCTGgtgagtagg > 45344_AB00189S CCCCAAATTATgtaagtcaa > 45344_AB00189S AATGAAAATAAgtacgtcac > 45344_AB00189S AGATTACACAGgtaatgagc > 45344_AB00189S AAGACCAGCAGgtaatgcat > 45345_AB002059 TATGTGGTAGGgtaagagag > 45345_AB002059 AGCCACCTCAGgtgggggcc > 45345_AB002059 GATGCCCAGAGgtgagttta > 45345_AB002059 ACACAGCCACGgtaactgtg > 45345_AB002059 GTTGTGCCCTCgtaagtgtc > 45345_AB002059 AACTTCTCTAAgtaagcaga > 45345_AB002059 TGGCGTTGCTGgtgggtccc" > </form>--> <!-- <form method="post" action="create.cgi"> <input type="submit" name="cmd_edit" value="Edit Logo" > Intron-Exon (Acceptor) Sites <input type="hidden" name="logo_title" value="intron | exon" > <input type="hidden" name="first_index" value="-21" > <input type="hidden" name="logo_start" value="-20" > <input type="hidden" name="logo_end" value="3" > <input type="hidden" name="show_xaxis" value="true" > <input type="hidden" name="show_yaxis" value="true" > <input type="hidden" name="show_errorbars" value="true" > <input type="hidden" name="show_fineprint" value="true" > <input type="hidden" name="scale_width" value="true" > <input type="hidden" name="sequences" value=" > 19082_AF115399 ttctctgaaatatgaatttagACTGGTACTTATCATGGAG > 45328_AB000381 gcctgctttctcccctctcagGGACTTACAGTTTGAGATG > 45328_AB000381 cattgctgcttctttttttagGCATAAATTCTCGTGAACT > 45330_AB001517 aacttcctgtgtgttttgcagACAGCTGGATAGAAAACGA > 45331_AB001517 acaattttgttttcttcacagTTTTCAAATTTGCTGGGTA > 45331_AB001517 tgtggtttttgtctttatcagCAACAAATCTGACACGCTG > 45331_AB001517 gtgacctctggcgtcctgcagGGGGCGATGCGCTGCTGGT > 45331_AB001517 atgtccgcgttccttccatagGAAGTTTGTTGTCACAAAG > 45331_AB001517 tgccatctccctcttttccagGTGCTTTGTGGTTGGGAGC > 45331_AB001517 accctgtgcttccccttgcagCTGTACTCACTCAGCCAGG > 45331_AB001517 tcttctctctcgtcaattcagGTACTTCTTCAATAAAGAA > 45331_AB001517 ttacaggcccgttctctgcagCATTTCAGATCAGAGCATC > 45331_AB001517 cagcttcccccgtgtgcacagGCCTGGGCCAGCTGCTGGT > 45331_AB001517 gcccctcctgtcctgcctcagGTCAAGGTGTGGAACACCC > 45331_AB001517 gaccttgcctcttctctgcagGTACCGAAACTTCCGCACC > 45331_AB001517 cgcctccttgctctacggtagGTTTTGTCTGGACACGAAG > 45331_AB001517 ttactttgcatctctgtttagCTCTGGCTGTGACTTTTCG > 45331_AB001517 ccatgtctcctctccacccagGGCCTTCACCGCCCTGTGC > 45331_AB001517 ccactgcttttgctgttctagGAATTTTTGAACCGAAGAA > 45331_AB001517 taacggttcttttttccccagGTGACATGAGTTCTCGGCA > 45331_AB001517 aagcactgcttaatttcccagGGCGCTGCTGGGCGGCCAC > 45331_AB001517 tgattttttctccttttgcagTTGAAGTGGTCACCTCCTC > 45331_AB001517 cttagggagtctccctttcagAGCCGGGACGCTGCTGCCT > 45331_AB001517 catcccctgtgtgattgacagCTGTAGCTGGAACCACTAT > 45332_AB001517 cagctcccgctcctctcgcagGTGCTGTCTGGATGCGGAG > 45332_AB001517 ctctggttttcccccgtgcagGATCCTGGTGCACCTGAGC > 45332_AB001517 ttgccctgtgctctttcccagGAATGTTTTGACCGAGTCT > 45332_AB001517 aggccttttgtctcccggtagGAGCACGTTTGCCGTGGAC > 45332_AB001517 cgtgttcttttcgcctttcagCTTGTGCTGCATTGCACCT > 45333_AB001517 cagctcccgctcctctcgcagGTGCTGTCTGGATGCGGAG > 45333_AB001517 ctctggttttcccccgtgcagGATCCTGGTGCACCTGAGC > 45333_AB001517 ttgccctgtgctctttcccagGAATGTTTTGACCGAGTCT > 45333_AB001517 cgtgttcttttcgcctttcagCTTGTGCTGCATTGCACCT > 45334_AB001523 atttctttcttcccttcatagGTGCTGGAGATCAGAATTT > 45334_AB001523 acttcaaacaattgtttacagGTCCTATGGCCGGGCTCCG > 45334_AB001523 cagtgacttgtttgtttttagGATACCGAAGTGTATAAAG > 45334_AB001523 agtctgttcatgtctttgcagGTGTGTTGTGCTCTCCGAC > 45334_AB001523 aaacgtatcttgggcgaatagGAGGAGCTTGCCTTTGTTT > 45334_AB001523 tcatgatgtgtgtttgtttagATGGTGCCAACTGGCTGAC > 45334_AB001523 ttcgcatttgcacccccacagGTCTCTGTCCCACCTGGTG > 45334_AB001523 attgtggatttatcttaacagTTAAAGTCCTTGGGCTATC > 45334_AB001523 tctcgtttctttctgtttaagCCAACACAGCTCAGAGTCC > 45334_AB001523 tgtgtttttacttccccacagGATTTGTCCCATGCCACCA > 45334_AB001523 actgtttgttgactttgcaagGAGGAAAAAGGCTCCACAA > 45334_AB001523 ctccttacctctccgctccagCTACCTGCAGACCAGCAGC > 45334_AB001523 tacgataatgtctatttacagGTCATAAGATAGTGCTACC > 45334_AB001523 tgcctgattctttgactctagGCCAAGGAACCTGGAACGT > 45334_AB001523 ccacgatctcttttcctttagATAGCCTTCTGGCAGGCAT > 45334_AB001523 gactttttctgtccttcgtagAACAGTCTTCTGAGGCCGC > 45334_AB001523 gtctttgtgcttcctcctcagGTGTCGATTGACTGCCCGT > 45334_AB001523 ctttttgtttttccactttagGAAATATGTTCAAGTTTGT > 45334_AB001523 gacccccaactctctttccagCCCATCTACAGCAAGCAGT > 45334_AB001523 ttctctccctttcctgcccagACATTATACAACGTGAAGG > 45334_AB001523 catcgcttcctctcgtttcagTTGTCGACAACAGTAGCAA > 45334_AB001523 aacttcctgtgtgttttgcagACAGCTGGATAGAAAACGA > 45335_AB001523 acaattttgttttcttcacagTTTTCAAATTTGCTGGGTA > 45337_AB00189S ttgtgtctttcgtgcttacagCATTGTGGCGACAAGAACA > 45337_AB00189S caccacgattccatttcttagGATTCCTACGCCAGCTACG > 45337_AB00189S tggttttttcctttgtttcagACACGGCACTCGTTGTGCG > 45338_AB00189S ttgtgtctttcgtgcttacagCATTGTGGCGACAAGAACA > 45338_AB00189S caccacgattccatttcttagGATTCCTACGCCAGCTACG > 45338_AB00189S tggttttttcctttgtttcagACACGGCACTCGTTGTGCG > 45338_AB00189S aatgcattctttacccattagGTGATCTTGAGACTCCTGT > 45339_AB00189S ttgtgtctttcgtgcttacagCATTGTGGCGACAAGAACA > 45339_AB00189S caccacgattccatttcttagGATTCCTACGCCAGCTACG > 45339_AB00189S tggttttttcctttgtttcagACACGGCACTCGTTGTGCG > 45339_AB00189S aatgcattctttacccattagGTGATCTTGAGACTCCTGT > 45340_AB00189S ttgtgtctttcgtgcttacagCATTGTGGCGACAAGAACA > 45340_AB00189S caccacgattccatttcttagGATTCCTACGCCAGCTACG > 45340_AB00189S tggttttttcctttgtttcagACACGGCACTCGTTGTGCG > 45341_AB00189S ttgtgtctttcgtgcttacagCATTGTGGCGACAAGAACA > 45341_AB00189S caccacgattccatttcttagGATTCCTACGCCAGCTACG > 45341_AB00189S tggttttttcctttgtttcagACACGGCACTCGTTGTGCG > 45341_AB00189S ctcctgcctttgctcctacagGAAGTGCGTGAGTGTGTGC > 45342_AB00189S ttgtgtctttcgtgcttacagCATTGTGGCGACAAGAACA > 45342_AB00189S caccacgattccatttcttagGATTCCTACGCCAGCTACG > 45342_AB00189S tggttttttcctttgtttcagACACGGCACTCGTTGTGCG > 45342_AB00189S -ggcaatttgcactcacacagCTCAATCCACCCCAGGCTC > 45342_AB00189S ctcctgcctttgctcctacagGAAGTGCGTGAGTGTGTGC > 45342_AB00189S aggaacggtatcttcccacagGTGTGACGAGAACTGCTTG > 45342_AB00189S tttcctgatgcggggccccagCTGACGAGACATTCTGCGA > 45343_AB00189S ttgtgtctttcgtgcttacagCATTGTGGCGACAAGAACA > 45343_AB00189S caccacgattccatttcttagGATTCCTACGCCAGCTACG > 45343_AB00189S tggttttttcctttgtttcagACACGGCACTCGTTGTGCG > 45343_AB00189S ctcctgcctttgctcctacagGAAGTGCGTGAGTGTGTGC > 45343_AB00189S aggaacggtatcttcccacagGTGTGACGAGAACTGCTTG > 45343_AB00189S tttcctgatgcggggccccagCTGACGAGACATTCTGCGA > 45344_AB00189S ttgtgtctttcgtgcttacagCATTGTGGCGACAAGAACA > 45344_AB00189S caccacgattccatttcttagGATTCCTACGCCAGCTACG > 45344_AB00189S tggttttttcctttgtttcagACACGGCACTCGTTGTGCG > 45344_AB00189S -ggcaatttgcactcacacagCTCAATCCACCCCAGGCTC > 45344_AB00189S ctcctgcctttgctcctacagGAAGTGCGTGAGTGTGTGC > 45345_AB002059 tgcccgacttctcctccccagGTGGGCGCTCCTCGCCAAA > 45345_AB002059 accttgagacttgcctcctagGGAGAGAACGTGTTCTTCT > 45345_AB002059 ctgctctctctcccacctcagCACCCGTCCGTCCCACTGG > 45345_AB002059 agttcatcttttgttttctagGTGTAAAAACAGGCCAGTG > 45345_AB002059 tcacctcccttccacctgcagGAGGCCCCTGCTGGCCCAG > 45345_AB002059 gacctttcccactcctcccagGTCCAATGCCTTGGAGACC > 45345_AB002059 aaagctatgtgctatgtgcagGGTGGCTCTGTAGGCATCA > 45345_AB002059 agccttctttcctgcccacagGACAGCCACTCACTGGTGG " > </form>-->--> </td></tr> </table> <script type="text/javascript"> var gaJsHost = (("https:" == document.location.protocol) ? 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