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| author | dcouvin |
|---|---|
| date | Wed, 08 Dec 2021 01:46:07 +0000 |
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#Gene_ID Gene_name Codon_pos Ref_nuc Ref_codon Res_codon Resistance PMID Mechanism Notes Required_mut gyrA gyrA 83 AGT S R,I,N,L,Y Nalidixic acid, Ciprofloxacin 12373497,9527801 Target modification Phenotype described only in association with parC mutations, unknown phenotype if the present mutation occurs alone gyrA gyrA 87 GAG E K,G,L Nalidixic acid, Ciprofloxacin 12373497,12373497,12373497 Target modification Phenotype described only in association with parC mutations, unknown phenotype if the present mutation occurs alone gyrA gyrA 97 AGT S N Nalidixic acid, Ciprofloxacin 10508034 Target modification Phenotype described only in association with parC mutations, unknown phenotype if the present mutation occurs alone parC parC 80 AGC S R,I Nalidixic acid, Ciprofloxacin 12373497,12373497 Target modification parC parC 84 GAA E A,K,T Nalidixic acid, Ciprofloxacin 12373497,9527801 Target modification pbp5 pbp5 24 GTA V A Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 27 AGT S G Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 34 CGG R Q Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 66 GGA G E Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 68 GCA A T Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 85 GAA E D Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 100 GAG E Q Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 144 AAA K Q Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 172 ACA T A Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 177 TTA L I Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 204 GAC D G Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 216 GCA A S Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 324 ACA T A Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 485 ATG M A,T Ampicillin 25182648,25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 496 AAT N K Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 499 GCA A T,I Ampicillin 25182648,25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 525 GAG E D Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 586 GTA V L Ampicillin 25182648 Target modification Not essential for resistance phenotype pbp5 pbp5 629 GAA E V Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype pbp5 pbp5 667 CCC P S Ampicillin 25182648 Target modification The nineteen pbp5 mutations must be present simultaneously for resistance phenotype # Indels pbp5 pbp5 466 - ins S,D Ampicillin 25182648,25182648 Target modification Not essential for resistance phenotype