changeset 19:c0096052b35b draft

planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/trinity commit 1d443e73d2eb888660bbbc7af198f5bcca9c1a70
author iuc
date Tue, 11 Apr 2023 19:55:15 +0000
parents 3f4094b6a565
children 9871e84c26ee
files analyze_diff_expr.xml macros.xml test-data/count/define_clusters_by_cutting_tree/my_cluster_plots.pdf test-data/count/define_clusters_by_cutting_tree/subcluster_1_log2_medianCentered_fpkm.matrix test-data/count/define_clusters_by_cutting_tree/subcluster_2_log2_medianCentered_fpkm.matrix test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.DESeq2.DE_results test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.DESeq2.DE_results.MA_n_Volcano.pdf test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.edgeR.DE_results test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.edgeR.DE_results.MA_n_Volcano.pdf test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.voom.DE_results test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.voom.DE_results.MA_n_Volcano.pdf test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.DESeq2.DE_results test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.DESeq2.DE_results.MA_n_Volcano.pdf test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.edgeR.DE_results test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.edgeR.DE_results.MA_n_Volcano.pdf test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.voom.DE_results test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.voom.DE_results.MA_n_Volcano.pdf test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.DESeq2.DE_results test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.DESeq2.DE_results.MA_n_Volcano.pdf test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.edgeR.DE_results test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.edgeR.DE_results.MA_n_Volcano.pdf test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.voom.DE_results test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.voom.DE_results.MA_n_Volcano.pdf test-data/count/qcheck/input.matrix.CPM.log2.prcomp.principal_components.pdf test-data/count/qcheck/input.matrix.CPM.log2.sample_cor_matrix.pdf test-data/count/qcheck/wt_37.rep_compare.pdf test-data/count/qcheck/wt_GSNO.rep_compare.pdf test-data/count/qcheck/wt_ph8.rep_compare.pdf test-data/filtered/Trinity_filtered_exp.fasta test-data/filtered/Trinity_filtered_hi_iso.fasta test-data/filtered/Trinity_filtered_pct_iso.fasta
diffstat 31 files changed, 398 insertions(+), 384 deletions(-) [+]
line wrap: on
line diff
--- a/analyze_diff_expr.xml	Sun Dec 19 16:21:54 2021 +0000
+++ b/analyze_diff_expr.xml	Tue Apr 11 19:55:15 2023 +0000
@@ -1,15 +1,10 @@
-<tool id="trinity_analyze_diff_expr" name="Extract and cluster differentially expressed transcripts" version="@WRAPPER_VERSION@">
+<tool id="trinity_analyze_diff_expr" name="Extract and cluster differentially expressed transcripts" version="@TOOL_VERSION@+galaxy@VERSION_SUFFIX@" profile="21.05">
     <description>from a Trinity assembly</description>
     <macros>
         <import>macros.xml</import>
     </macros>
     <expand macro="bio_tools"/>
-    <expand macro="requirements">
-        <requirement type="package" version="2.18.0">bioconductor-qvalue</requirement>
-        <requirement type="package" version="1.36.0">bioconductor-goseq</requirement>
-        <requirement type="package" version="2.0.8">r-cluster</requirement>
-        <requirement type="package" version="1.1.25">r-fastcluster</requirement>
-    </expand>
+    <expand macro="requirements"/>
     <command detect_errors="aggressive"><![CDATA[
     ## DE results input files must be in the working directory and have suffix .DE_results
     #import re
@@ -35,8 +30,8 @@
     analyze_diff_expr.pl
         --matrix '${matrix}'
         --samples '${samples}'
-        -P ${p}
-        -C ${c}
+        -P ${P}
+        -C ${C}
 
         #if str( $additional_params.max_DE_genes_per_comparison ):
             --max_DE_genes_per_comparison ${additional_params.max_DE_genes_per_comparison}
@@ -57,26 +52,26 @@
         --output results
     ]]></command>
     <inputs>
-        <param format="tabular" name="matrix" argument="--matrix" type="data" label="Expression matrix" help="Raw counts matrix produced by 'Build expression matrix for a de novo assembly of RNA-Seq data by Trinity' tool"/>
-        <param format="tabular" name="samples" argument="--samples" type="data" label="Sample description" help="File describing samples and replicates"/>
-        <param format="tabular" name="DE_results" type="data_collection" collection_type="list" label="Differential expression results" help="Generated by 'Differential expression analysis using a Trinity assembly' tool"/>
-        <param name="p" type="float" argument="-P" value="0.001" label="p-value cutoff for FDR"/>
-        <param name="c" type="float" argument="-C" value="2" label="min abs(log2(a/b)) fold change" help="Default: 2 (meaning 2^(2) or 4-fold"/>
+        <param argument="--matrix" format="tabular" type="data" label="Expression matrix" help="Raw counts matrix produced by 'Build expression matrix for a de novo assembly of RNA-Seq data by Trinity' tool"/>
+        <param argument="--samples" format="tabular" type="data" label="Sample description" help="File describing samples and replicates"/>
+        <param name="DE_results" format="tabular" type="data_collection" collection_type="list" label="Differential expression results" help="Generated by 'Differential expression analysis using a Trinity assembly' tool"/>
+        <param argument="-P" type="float" value="0.001" label="p-value cutoff for FDR"/>
+        <param argument="-C" type="float" value="2" label="min abs(log2(a/b)) fold change" help="Default: 2 (meaning 2^(2) or 4-fold"/>
         <section name="additional_params" title="Additional Options" expanded="False">
-            <param name="max_DE_genes_per_comparison" argument="--max_DE_genes_per_comparison" type="integer" value="" optional="true" label="Maximum differential expression genes per comparison" help="Extract only up to the top number of DE features within each pairwise comparison. This is useful when you have massive numbers of DE features but still want to make useful heatmaps and other plots with more manageable numbers of data points."/>
-            <param name="order_columns_by_samples_file" argument="--order_columns_by_samples_file" type="boolean" checked="false" truevalue="--order_columns_by_samples_file" falsevalue="" label="Order columns by samples file" help="Instead of clustering samples or replicates hierarchically based on gene expression patterns, order columns according to order in the --samples file."/>
-            <param name="max_genes_clust" argument="--max_genes_clust" type="integer" value="10000" label="Maximum genes in cluster" help="If more than 10000, heatmaps are not generated, since too time consuming"/>
+            <param argument="--max_DE_genes_per_comparison" type="integer" value="" optional="true" label="Maximum differential expression genes per comparison" help="Extract only up to the top number of DE features within each pairwise comparison. This is useful when you have massive numbers of DE features but still want to make useful heatmaps and other plots with more manageable numbers of data points."/>
+            <param argument="--order_columns_by_samples_file" type="boolean" checked="false" truevalue="--order_columns_by_samples_file" falsevalue="" label="Order columns by samples file" help="Instead of clustering samples or replicates hierarchically based on gene expression patterns, order columns according to order in the --samples file."/>
+            <param argument="--max_genes_clust" type="integer" value="10000" label="Maximum genes in cluster" help="If more than 10000, heatmaps are not generated, since too time consuming"/>
             <conditional name="GO_enrichment">
-                <param type="select" name="examine_GO_enrichment" argument="--examine_GO_enrichment" label="Run GO enrichment analysis" help="To examine GO enrichment, you must first run Trinotate and then extract all GO assignments for each gene feature, with the Trinotate script extract_GO_assignments_from_Trinotate_xls.pl">
+                <param argument="--examine_GO_enrichment" type="select" label="Run GO enrichment analysis" help="To examine GO enrichment, you must first run Trinotate and then extract all GO assignments for each gene feature, with the Trinotate script extract_GO_assignments_from_Trinotate_xls.pl">
                     <option value="no">No</option>
                     <option value="yes">Yes</option>
                 </param>
                 <when value="no">
                 </when>
                 <when value="yes">
-                    <param format="tabular" name="DE_matrices" type="data_collection" collection_type="list" label="Differential expression count matrices" help="Generated by 'Differential expression analysis using a Trinity assembly' tool. If not, be careful that the file names are identical to the file names of differential expression results, with extension '.count_matrix' instead of '.DE_results'."/>
-                    <param format="tabular" name="GO_annots" argument="--GO_annots" type="data" label="Extracted GO assignments file" help="Generated by the Trinotate script extract_GO_assignments_from_Trinotate_xls.pl. Must have 2 columns: feature_id GO:000001,GO:00002,..."/>
-                    <param format="tabular" name="gene_lengths" argument="--gene_lengths" type="data" label="Gene length file" help="Must have 2 columns: feature_id length"/>
+                    <param name="DE_matrices" format="tabular" type="data_collection" collection_type="list" label="Differential expression count matrices" help="Generated by 'Differential expression analysis using a Trinity assembly' tool. If not, be careful that the file names are identical to the file names of differential expression results, with extension '.count_matrix' instead of '.DE_results'."/>
+                    <param argument="--GO_annots" format="tabular" type="data" label="Extracted GO assignments file" help="Generated by the Trinotate script extract_GO_assignments_from_Trinotate_xls.pl. Must have 2 columns: feature_id GO:000001,GO:00002,..."/>
+                    <param argument="--gene_lengths" format="tabular" type="data" label="Gene length file" help="Must have 2 columns: feature_id length"/>
                 </when>
         </conditional>
         </section>
@@ -93,7 +88,7 @@
             <data format="tabular" name="results_matrix_log2_sample_cor" from_work_dir="results.matrix.log2.sample_cor.dat"/>
             <data format="pdf" name="results_matrix_log2_sample_cor_matrix" from_work_dir="results.matrix.log2.sample_cor_matrix.pdf"/>
         </collection>
-        <data format="rdata" name="rdata" label="${tool.name} on ${on_string}: RData file" from_work_dir="results.matrix.RData"/>
+        <data name="rdata" format="rdata" label="${tool.name} on ${on_string}: RData file" from_work_dir="results.matrix.RData"/>
         <collection name="GOseq_enrichment" type="list" label="${tool.name} on ${on_string}: GOseq enriched and depleted categories">
             <filter>additional_params['GO_enrichment']['examine_GO_enrichment'] == 'yes'</filter>
             <discover_datasets pattern="(?P&lt;name&gt;.+\.subset\.GOseq\.(enriched|depleted))$" ext="tabular" />
--- a/macros.xml	Sun Dec 19 16:21:54 2021 +0000
+++ b/macros.xml	Tue Apr 11 19:55:15 2023 +0000
@@ -1,8 +1,7 @@
-<?xml version="1.0"?>
 <macros>
     <xml name="requirements">
         <requirements>
-            <requirement type="package" version="@WRAPPER_VERSION@">trinity</requirement>
+            <requirement type="package" version="@TOOL_VERSION@">trinity</requirement>
             <yield/>
         </requirements>
     </xml>
@@ -11,10 +10,11 @@
             <xref type="bio.tools">trinity</xref>
         </xrefs>
     </xml>
-    <token name="@WRAPPER_VERSION@">2.9.1</token>
+    <token name="@TOOL_VERSION@">2.15.1</token>
+    <token name="@VERSION_SUFFIX@">0</token>
 
     <token name="@COMMAND_PAIRED_STRAND_JACCARD@">
-        #if $pool.inputs.strand.is_strand_specific:
+        #if $pool.inputs.strand.is_strand_specific == 'true':
             --SS_lib_type $pool.inputs.strand.library_type
         #end if
 
@@ -23,7 +23,10 @@
 
     <xml name="input_paired_strand_jaccard">
         <conditional name="strand">
-            <param name="is_strand_specific" type="boolean" checked="false" label="Strand specific data"/>
+            <param name="is_strand_specific" type="select" label="Strand specific data">
+                <option value="false">No</option>
+                <option value="true">Yes</option>
+            </param>
             <when value="false" />
             <when value="true">
                 <param name="library_type" argument="--SS_lib_type" type="select" label="Strand-specific library type">
@@ -35,6 +38,22 @@
         <param argument="--jaccard_clip" type="boolean" truevalue="--jaccard_clip" falsevalue="" checked="false" label="Jaccard Clip options" help="Set if you expect high gene density with UTR overlap"/>
     </xml>
 
+    <xml name="is_strand_specific_f_r">
+        <conditional name="strand">
+            <param name="is_strand_specific" type="select" label="Strand specific data">
+                <option value="false">No</option>
+                <option value="true">Yes</option>
+            </param>
+            <when value="false"/>
+            <when value="true">
+                <param name="library_type" argument="--SS_lib_type" type="select" label="Strand-specific Library Type">
+                    <option value="F">F</option>
+                    <option value="R">R</option>
+                </param>
+            </when>
+        </conditional>
+    </xml>
+
     <xml name="citation">
         <citations>
             <citation type="doi">10.1038/nbt.1883</citation>
Binary file test-data/count/define_clusters_by_cutting_tree/my_cluster_plots.pdf has changed
--- a/test-data/count/define_clusters_by_cutting_tree/subcluster_1_log2_medianCentered_fpkm.matrix	Sun Dec 19 16:21:54 2021 +0000
+++ b/test-data/count/define_clusters_by_cutting_tree/subcluster_1_log2_medianCentered_fpkm.matrix	Tue Apr 11 19:55:15 2023 +0000
@@ -1,7 +1,7 @@
 wt_37_2	wt_37_3	wt_37_1	wt_ph8_3	wt_ph8_1	wt_ph8_2	wt_GSNO_3	wt_GSNO_1	wt_GSNO_2
+TR3788|c0_g1_i1	-1.22775484082629	-0.443483531881724	-0.874117886211586	-0.353285722910146	-0.874117886211586	-0.590324920210995	1.12588211378841	1.65760259323259	1.57960008123132
 TR24|c0_g1_i1	0.106533882165825	-0.313797916782532	0.025003996669227	1.39963914188743	1.22079106142351	1.25695072471892	-1.19180739240392	-1.23133575659056	-1.2719777410879
-TR2779|c0_g1_i1	-0.795433018475884	-1.23380302158535	-0.574143153586594	1.74646076035339	1.75438767612502	1.74380874666379	-1.13287411273457	-0.795433018475884	-0.712970858283911
 TR3091|c0_g1_i1	-2.42438780178849	-2.77802475640319	-2.62602166295814	1.43575453462855	1.4783149968566	1.36038927229391	1.02359379610527	1.32351327005887	1.20686835120661
-TR131|c0_g1_i1	-3.50802026981862	-3.6944333940495	-3.55241438917708	1.98577454287534	1.99158406095747	1.95736061514986	1.41625240401813	1.71671228997234	1.68718414007205
+TR2779|c0_g1_i1	-0.795433018475884	-1.23380302158535	-0.574143153586594	1.74646076035339	1.75438767612502	1.74380874666379	-1.13287411273457	-0.795433018475884	-0.712970858283911
 TR5075|c0_g1_i1	-1.04544737992556	-0.329240345926152	-0.393370683345868	2.50474970263492	2.07793503557972	2.30706903479522	-2.04544737992556	-1.68287730054085	-1.39337068334587
-TR3788|c0_g1_i1	-1.22775484082629	-0.443483531881724	-0.874117886211586	-0.353285722910146	-0.874117886211586	-0.590324920210995	1.12588211378841	1.65760259323259	1.57960008123132
+TR131|c0_g1_i1	-3.50802026981862	-3.6944333940495	-3.55241438917708	1.98577454287534	1.99158406095747	1.95736061514986	1.41625240401813	1.71671228997234	1.68718414007205
--- a/test-data/count/define_clusters_by_cutting_tree/subcluster_2_log2_medianCentered_fpkm.matrix	Sun Dec 19 16:21:54 2021 +0000
+++ b/test-data/count/define_clusters_by_cutting_tree/subcluster_2_log2_medianCentered_fpkm.matrix	Tue Apr 11 19:55:15 2023 +0000
@@ -1,8 +1,8 @@
 wt_37_2	wt_37_3	wt_37_1	wt_ph8_3	wt_ph8_1	wt_ph8_2	wt_GSNO_3	wt_GSNO_1	wt_GSNO_2
+TR2107|c1_g1_i1	2.49178842221691	2.62929194596684	2.16986032732955	-1.41510217339161	-2.41510217339161	-1.83013967267045	-0.607747251334006	-0.607747251334006	-0.41510217339161
+TR4761|c0_g1_i1	2.06406810079911	1.80544476674762	1.90822498634624	-0.339510283104669	-0.357888812419525	-0.296334141902888	-1.67981690730689	-1.51400801433681	-1.59017969482221
+TR5055|c0_g2_i1	1.90528891290538	0.865760548718745	1.50319046933404	-0.982236357836205	-0.982236357836205	0.280798047997588	-0.982236357836205	-0.304164452723568	-1.30416445272357
+TR2672|c0_g1_i1	0.965440325233136	1.96544032523314	1.58211168568163	0.965440325233136	-0.619522175488021	0.0585497296246169	-2.94145027037538	-0.619522175488021	-1.35648776965423
 TR4277|c0_g1_i1	3.24415794782388	3.31812623217364	3.18414689752048	-1.44630436384266	-1.5322044372483	-1.46308007659348	-1.98611482817144	-1.80411699442855	-1.51461037723356
-TR2672|c0_g1_i1	0.965440325233136	1.96544032523314	1.58211168568163	0.965440325233136	-0.619522175488021	0.0585497296246169	-2.94145027037538	-0.619522175488021	-1.35648776965423
 TR127|c1_g1_i1	1.25755965737847	2.52059406321227	2.02309440374145	-0.0643684375088904	-1.06436843750889	-1.06436843750889	-0.479405936787734	-2.06436843750889	-1.06436843750889
-TR2107|c1_g1_i1	2.49178842221691	2.62929194596684	2.16986032732955	-1.41510217339161	-2.41510217339161	-1.83013967267045	-0.607747251334006	-0.607747251334006	-0.41510217339161
-TR5055|c0_g2_i1	1.90528891290538	0.865760548718745	1.50319046933404	-0.982236357836205	-0.982236357836205	0.280798047997588	-0.982236357836205	-0.304164452723568	-1.30416445272357
-TR4761|c0_g1_i1	2.06406810079911	1.80544476674762	1.90822498634624	-0.339510283104669	-0.357888812419525	-0.296334141902888	-1.67981690730689	-1.51400801433681	-1.59017969482221
 TR1894|c2_g1_i1	2.11263053903627	1.56008951600749	1.23816142112012	-1.34680107960103	-0.346801079601032	-1.34680107960103	-1.34680107960103	-0.761838578879876	0.238161421120124
--- a/test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.DESeq2.DE_results	Sun Dec 19 16:21:54 2021 +0000
+++ b/test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.DESeq2.DE_results	Tue Apr 11 19:55:15 2023 +0000
@@ -1,38 +1,38 @@
 sampleA	sampleB	baseMeanA	baseMeanB	baseMean	log2FoldChange	lfcSE	stat	pvalue	padj
-TR4277|c0_g1_i1	wt_37	wt_GSNO	3852.97388871986	161.116814813422	2007.04535176664	4.57661492404411	0.121615845393926	37.6317321909822	0	0
-TR131|c0_g1_i1	wt_37	wt_GSNO	26.1866396538608	1340.30918254958	683.247911101723	-5.68565819121436	0.188173369545147	-30.2149990987446	1.50487696827007e-200	2.48304699764561e-199
-TR4761|c0_g1_i1	wt_37	wt_GSNO	1645.20640957447	193.196157329029	919.201283451752	3.09227622940716	0.143766888218038	21.5089598706302	1.28350063536341e-102	1.41185069889975e-101
-TR3091|c0_g1_i1	wt_37	wt_GSNO	16.7444693227929	328.569936894811	172.657203108802	-4.30529554105297	0.242003292489129	-17.790235400398	8.41257542125902e-71	6.94037472253869e-70
-TR3638|c0_g1_i1	wt_37	wt_GSNO	583.00358519031	183.754416330029	383.37900076017	1.66225356244238	0.144704273829595	11.487245804501	1.5290952692426e-30	1.00920287770012e-29
-TR2487|c0_g1_i1	wt_37	wt_GSNO	342.210853400436	920.407318992504	631.30908619647	-1.42823125318501	0.124766100464837	-11.44727011475	2.42667678803784e-30	1.33467223342081e-29
-TR3788|c0_g1_i1	wt_37	wt_GSNO	19.5075441237117	134.95369713876	77.2306206312357	-2.78185518936858	0.26452057618315	-10.5165928091827	7.24461724546031e-26	3.41531955857415e-25
-TR1479|c0_g1_i1	wt_37	wt_GSNO	129.593534475689	371.064629188207	250.329081831948	-1.51632040995179	0.145721574162902	-10.405599985193	2.33778717307793e-25	9.64337208894648e-25
-TR2107|c1_g1_i1	wt_37	wt_GSNO	48.9228907410258	7.40521775805688	28.1640542495414	2.72565745131165	0.439033221898883	6.20831708252687	5.35550100392654e-10	1.96368370143973e-09
-TR3854|c0_g1_i1	wt_37	wt_GSNO	1573.69549271337	2374.56159860719	1974.12854566028	-0.593952181868433	0.11125243839418	-5.33877900063632	9.35746226940931e-08	3.08796254890507e-07
-TR2122|c0_g2_i2	wt_37	wt_GSNO	119.534640490118	199.143666337033	159.339153413576	-0.73989736621081	0.168946597067547	-4.37947481070002	1.18965671308434e-05	3.56897013925302e-05
-TR1449|c0_g1_i1	wt_37	wt_GSNO	180.814952011467	104.755290736358	142.785121373912	0.785811747593425	0.186397685526418	4.2157806057203	2.48915666101662e-05	6.6882655779165e-05
-TR4163|c0_g1_i1	wt_37	wt_GSNO	347.283468916919	232.772947466212	290.028208191566	0.5773903092812	0.137377906430929	4.20293425836637	2.63477128827014e-05	6.6882655779165e-05
-TR2672|c0_g1_i1	wt_37	wt_GSNO	18.3155337236093	2.26581902751323	10.2906763755613	2.9857084616452	0.761209385049731	3.92232218924907	8.76996107235725e-05	0.000206720510991278
-TR5055|c0_g2_i1	wt_37	wt_GSNO	23.3590211688541	5.52768338415684	14.4433522765055	2.08513896568298	0.577312677901881	3.61180179389265	0.00030407694239889	0.000668969273277559
-TR2844|c0_g1_i1	wt_37	wt_GSNO	158.206282615139	231.762548186068	194.984415400603	-0.551426184671915	0.155135532159318	-3.55448024702441	0.000378726959348647	0.000781124353656584
-TR127|c1_g1_i1	wt_37	wt_GSNO	13.461799216177	1.21881296083961	7.34030608850831	3.52517488060096	1.00261297574214	3.51598769005717	0.00043812129728732	0.000850470753557739
-TR5212|c0_g1_i1	wt_37	wt_GSNO	65.7079302129484	107.875371765755	86.7916509893515	-0.715754705745061	0.210644233010842	-3.39793164766215	0.000678973819799399	0.0012447853362989
-TR1894|c2_g1_i1	wt_37	wt_GSNO	13.3497721959996	2.96749216411516	8.15863218005739	2.116499695166	0.744618031030184	2.84239651333424	0.00447757649596373	0.00777684338772647
-TR24|c0_g1_i1	wt_37	wt_GSNO	69.9065207344592	41.2394742844514	55.5729975094553	0.763675526543044	0.270944643994893	2.81856660933825	0.00482386011442888	0.00795936918880766
+TR4277|c0_g1_i1	wt_37	wt_GSNO	3852.97388871986	161.116814813422	2007.04535176664	4.57661492404411	0.121615845393921	37.6317321909836	0	0
+TR131|c0_g1_i1	wt_37	wt_GSNO	26.1866396538608	1340.30918254958	683.247911101723	-5.68565819121436	0.188173369545145	-30.214999098745	1.5048769682518e-200	2.48304699761546e-199
+TR4761|c0_g1_i1	wt_37	wt_GSNO	1645.20640957447	193.196157329029	919.201283451752	3.09227622940716	0.143766888218033	21.5089598706309	1.28350063534336e-102	1.41185069887769e-101
+TR3091|c0_g1_i1	wt_37	wt_GSNO	16.7444693227929	328.569936894811	172.657203108802	-4.30529554105297	0.242003292489129	-17.790235400398	8.41257542126328e-71	6.94037472254221e-70
+TR3638|c0_g1_i1	wt_37	wt_GSNO	583.00358519031	183.754416330029	383.37900076017	1.66225356244238	0.144704273829591	11.4872458045013	1.52909526923641e-30	1.00920287769603e-29
+TR2487|c0_g1_i1	wt_37	wt_GSNO	342.210853400436	920.407318992504	631.30908619647	-1.42823125318502	0.124766100464834	-11.4472701147503	2.42667678802884e-30	1.33467223341586e-29
+TR3788|c0_g1_i1	wt_37	wt_GSNO	19.5075441237117	134.95369713876	77.2306206312357	-2.78185518936858	0.264520576183151	-10.5165928091826	7.24461724546331e-26	3.41531955857556e-25
+TR1479|c0_g1_i1	wt_37	wt_GSNO	129.593534475689	371.064629188207	250.329081831948	-1.5163204099518	0.145721574162894	-10.4055999851936	2.33778717306381e-25	9.6433720888882e-25
+TR2107|c1_g1_i1	wt_37	wt_GSNO	48.9228907410258	7.40521775805688	28.1640542495414	2.72565745131165	0.439033221898883	6.20831708252687	5.35550100392651e-10	1.96368370143972e-09
+TR3854|c0_g1_i1	wt_37	wt_GSNO	1573.69549271337	2374.56159860719	1974.12854566028	-0.593952181868431	0.11125243839418	-5.33877900063628	9.3574622694111e-08	3.08796254890566e-07
+TR2122|c0_g2_i2	wt_37	wt_GSNO	119.534640490118	199.143666337033	159.339153413576	-0.739897366210811	0.168946597067543	-4.37947481070013	1.18965671308372e-05	3.56897013925116e-05
+TR1449|c0_g1_i1	wt_37	wt_GSNO	180.814952011467	104.755290736358	142.785121373912	0.785811747593426	0.186397685526415	4.21578060572037	2.48915666101586e-05	6.68826557791634e-05
+TR4163|c0_g1_i1	wt_37	wt_GSNO	347.283468916919	232.772947466212	290.028208191566	0.577390309281198	0.137377906430928	4.20293425836637	2.63477128827007e-05	6.68826557791634e-05
+TR2672|c0_g1_i1	wt_37	wt_GSNO	18.3155337236093	2.26581902751323	10.2906763755613	2.9857084616452	0.76120938504973	3.92232218924907	8.76996107235725e-05	0.000206720510991278
+TR5055|c0_g2_i1	wt_37	wt_GSNO	23.3590211688541	5.52768338415684	14.4433522765055	2.08513896568298	0.577312677901881	3.61180179389265	0.000304076942398887	0.000668969273277552
+TR2844|c0_g1_i1	wt_37	wt_GSNO	158.206282615139	231.762548186068	194.984415400603	-0.551426184671918	0.155135532159314	-3.55448024702451	0.000378726959348502	0.000781124353656284
+TR127|c1_g1_i1	wt_37	wt_GSNO	13.461799216177	1.21881296083961	7.34030608850831	3.52517488060096	1.00261297574214	3.51598769005718	0.000438121297287318	0.000850470753557735
+TR5212|c0_g1_i1	wt_37	wt_GSNO	65.7079302129484	107.875371765755	86.7916509893515	-0.715754705745063	0.210644233010843	-3.39793164766215	0.000678973819799395	0.00124478533629889
+TR1894|c2_g1_i1	wt_37	wt_GSNO	13.3497721959996	2.96749216411516	8.15863218005739	2.116499695166	0.744618031030184	2.84239651333424	0.00447757649596375	0.00777684338772651
+TR24|c0_g1_i1	wt_37	wt_GSNO	69.9065207344592	41.2394742844514	55.5729975094553	0.763675526543045	0.270944643994892	2.81856660933826	0.00482386011442872	0.00795936918880738
 TR4669|c0_g2_i1	wt_37	wt_GSNO	0	167.096667347181	83.5483336735905	-10.0466852501689	3.90738405199054	-2.57120495873725	0.0101345328521317	0.0159256944819212
-TR2779|c0_g1_i1	wt_37	wt_GSNO	155.915506826481	205.619872596257	180.767689711369	-0.403209397282846	0.18950756245476	-2.12766916559914	0.033364523163095	0.0500467847446426
-TR3807|c0_g1_i1	wt_37	wt_GSNO	3.48709246029019	0.350050334268211	1.9185713972792	3.04810928058763	1.5874506366217	1.92012854464212	0.0548416645360559	0.0786858665082542
-TR1492|c0_g1_i2	wt_37	wt_GSNO	1640.89375005483	1435.64893261411	1538.27134133447	0.192601921423703	0.101311986688049	1.90107733270247	0.0572918841322824	0.0787763406818883
-TR4084|c0_g1_i1	wt_37	wt_GSNO	93.2264707954139	121.352438036668	107.289454416041	-0.381231151484282	0.21399248813321	-1.78151651401411	0.0748281095286258	0.0987731045777861
-TR1891|c0_g1_i1	wt_37	wt_GSNO	107.628573623499	135.399287466928	121.513930545214	-0.329513668205708	0.189733845104182	-1.7367152814764	0.0824374390602291	0.104632134191829
-TR1837|c2_g1_i1	wt_37	wt_GSNO	0.308903905435236	2.22601224010275	1.26745807276899	-2.87715913917267	1.7927876855897	-1.60485213184979	0.108526350064413	1
-TR5075|c0_g1_i1	wt_37	wt_GSNO	15.8633018853512	9.23822794034992	12.5507649128506	0.776103293030194	0.516446682273215	1.5027752518693	0.13289700980576	0.16070937436521
-TR4859|c0_g1_i1	wt_37	wt_GSNO	7.32690480813971	3.17910584569163	5.25300532691567	1.23041974278822	0.82607009598701	1.48948587869905	0.13635946915836	0.16070937436521
-TR939|c0_g1_i1	wt_37	wt_GSNO	84.2568220960088	96.9171174594069	90.5869697777078	-0.203187486812458	0.203052234052517	-1.00066609835923	0.316988262617008	0.354139456794138
-TR2278|c0_g1_i1	wt_37	wt_GSNO	486.5272515724	448.140178813055	467.333715192727	0.118924512672215	0.120068895863502	0.990468945491189	0.321944960721944	0.354139456794138
-TR2011|c5_g1_i1	wt_37	wt_GSNO	5.60408627995835	7.88255079488408	6.74331853742122	-0.50342873702063	0.712267625142964	-0.706797163383052	0.479692537619295	0.510640443272153
-TR2182|c3_g2_i6	wt_37	wt_GSNO	2.24974854180929	1.3031439398571	1.77644624083319	0.878491642458712	1.45214866443311	0.604959852923637	0.545205672528741	0.562243349795264
+TR2779|c0_g1_i1	wt_37	wt_GSNO	155.915506826481	205.619872596257	180.767689711369	-0.403209397282847	0.189507562454757	-2.12766916559918	0.0333645231630914	0.0500467847446371
+TR3807|c0_g1_i1	wt_37	wt_GSNO	3.48709246029019	0.350050334268211	1.9185713972792	3.04810928058763	1.5874506366217	1.92012854464212	0.054841664536056	0.0786858665082543
+TR1492|c0_g1_i2	wt_37	wt_GSNO	1640.89375005483	1435.64893261411	1538.27134133447	0.192601921423702	0.101311986688034	1.90107733270273	0.0572918841322478	0.0787763406818408
+TR4084|c0_g1_i1	wt_37	wt_GSNO	93.2264707954139	121.352438036668	107.289454416041	-0.381231151484283	0.213992488133209	-1.78151651401413	0.0748281095286238	0.0987731045777834
+TR1891|c0_g1_i1	wt_37	wt_GSNO	107.628573623499	135.399287466928	121.513930545214	-0.329513668205707	0.189733845104182	-1.73671528147639	0.0824374390602302	0.104632134191831
+TR1837|c2_g1_i1	wt_37	wt_GSNO	0.308903905435236	2.22601224010275	1.26745807276899	-2.87715913917267	1.7927876855897	-1.60485213184978	0.108526350064413	1
+TR5075|c0_g1_i1	wt_37	wt_GSNO	15.8633018853512	9.23822794034992	12.5507649128506	0.776103293030194	0.516446682273216	1.5027752518693	0.132897009805761	0.160709374365211
+TR4859|c0_g1_i1	wt_37	wt_GSNO	7.32690480813971	3.17910584569163	5.25300532691567	1.23041974278822	0.82607009598701	1.48948587869905	0.136359469158361	0.160709374365211
+TR939|c0_g1_i1	wt_37	wt_GSNO	84.2568220960088	96.9171174594069	90.5869697777078	-0.203187486812456	0.203052234052516	-1.00066609835922	0.316988262617012	0.35413945679411
+TR2278|c0_g1_i1	wt_37	wt_GSNO	486.5272515724	448.140178813055	467.333715192727	0.118924512672213	0.120068895863495	0.990468945491242	0.321944960721918	0.35413945679411
+TR2011|c5_g1_i1	wt_37	wt_GSNO	5.60408627995835	7.88255079488408	6.74331853742122	-0.503428737020628	0.712267625142964	-0.70679716338305	0.479692537619297	0.510640443272154
+TR2182|c3_g2_i6	wt_37	wt_GSNO	2.24974854180929	1.3031439398571	1.77644624083319	0.878491642458711	1.45214866443311	0.604959852923636	0.545205672528742	0.562243349795265
 TR3249|c0_g1_i1	wt_37	wt_GSNO	1.12573841927462	2.128954842887	1.62734663108081	-0.858277190977929	1.45820967054459	-0.588582841216099	0.556141147160533	1
 TR1678|c0_g1_i1	wt_37	wt_GSNO	0.595141051681226	0.700100668536423	0.647620860108824	-0.322353878735801	2.26929239960538	-0.142050393678601	0.887040200834538	1
-TR1122|c0_g1_i1	wt_37	wt_GSNO	1.41370386226057	1.3031439398571	1.35842390105883	0.189589394350501	1.67633508161709	0.113097552171736	0.909953215626095	1
-TR1982|c2_g1_i1	wt_37	wt_GSNO	5.73684100209948	5.71221669652109	5.72452884931028	-0.0104554076697487	0.738553450989727	-0.0141566025529196	0.988705042660126	0.988705042660126
+TR1122|c0_g1_i1	wt_37	wt_GSNO	1.41370386226057	1.3031439398571	1.35842390105883	0.1895893943505	1.67633508161709	0.113097552171736	0.909953215626095	1
+TR1982|c2_g1_i1	wt_37	wt_GSNO	5.73684100209948	5.71221669652109	5.72452884931028	-0.0104554076697489	0.738553450989728	-0.0141566025529198	0.988705042660126	0.988705042660126
Binary file test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.DESeq2.DE_results.MA_n_Volcano.pdf has changed
--- a/test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.edgeR.DE_results	Sun Dec 19 16:21:54 2021 +0000
+++ b/test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.edgeR.DE_results	Tue Apr 11 19:55:15 2023 +0000
@@ -1,38 +1,38 @@
 sampleA	sampleB	logFC	logCPM	PValue	FDR
-TR131|c0_g1_i1	wt_37	wt_GSNO	-5.83641794955382	16.0393491449056	0	0
-TR4277|c0_g1_i1	wt_37	wt_GSNO	4.41329536892161	17.453649857324	0	0
-TR3091|c0_g1_i1	wt_37	wt_GSNO	-4.45192710783926	14.0403115023365	4.66239713643175e-192	5.75028980159916e-191
-TR4761|c0_g1_i1	wt_37	wt_GSNO	2.92754337500687	16.3361488759619	3.05265683396309e-191	2.82370757141586e-190
-TR2487|c0_g1_i1	wt_37	wt_GSNO	-1.58705168340508	15.8893887856701	9.57106937146597e-124	7.08259133488482e-123
-TR1479|c0_g1_i1	wt_37	wt_GSNO	-1.67065982572176	14.5610246448295	4.39649357092684e-84	2.71117103540489e-83
-TR3638|c0_g1_i1	wt_37	wt_GSNO	1.49937182627392	15.1071990563814	1.60652562072048e-64	8.49163542380826e-64
-TR3854|c0_g1_i1	wt_37	wt_GSNO	-0.756864683109858	17.5153338325952	9.14141417630157e-40	4.22790405653948e-39
-TR2122|c0_g2_i2	wt_37	wt_GSNO	-0.90394318029981	13.8984589155106	3.98287653266084e-13	1.63740479676057e-12
-TR2844|c0_g1_i1	wt_37	wt_GSNO	-0.707834005847516	14.1849675326065	1.90004997002049e-12	7.0301848890758e-12
-TR3788|c0_g1_i1	wt_37	wt_GSNO	-2.92402824575823	12.8707284018497	1.35908019280542e-09	4.57145155761824e-09
-TR4669|c0_g2_i1	wt_37	wt_GSNO	-10.5373989771184	13.0207784411552	2.87822490296537e-08	8.87452678414323e-08
-TR2672|c0_g1_i1	wt_37	wt_GSNO	2.77705541360002	10.2430402179839	7.41806563943484e-08	2.11129560506992e-07
-TR4163|c0_g1_i1	wt_37	wt_GSNO	0.420123134789911	14.7306522277754	2.74345107938324e-06	7.25054928122714e-06
-TR127|c1_g1_i1	wt_37	wt_GSNO	3.26487561187968	9.85808314705506	6.1191913603037e-06	1.50940053554158e-05
-TR2107|c1_g1_i1	wt_37	wt_GSNO	2.54741701164587	11.489948731934	1.24782096095324e-05	2.88558597220436e-05
-TR2779|c0_g1_i1	wt_37	wt_GSNO	-0.571512278204146	14.0677635717422	7.39487278515011e-05	0.000160947231206208
-TR1894|c2_g1_i1	wt_37	wt_GSNO	1.88989717290856	9.93884262525918	0.00064827406279645	0.00133256335130381
-TR5055|c0_g2_i1	wt_37	wt_GSNO	1.89504810994952	10.6064804346292	0.00584438080176016	0.011381162613954
-TR3807|c0_g1_i1	wt_37	wt_GSNO	2.66606066906632	8.56455983886691	0.0188051214716541	0.0347894747225602
-TR5212|c0_g1_i1	wt_37	wt_GSNO	-0.867441722907523	13.0312878134755	0.0313380642877521	0.055214684697468
-TR1449|c0_g1_i1	wt_37	wt_GSNO	0.636828244112651	13.716963541734	0.0836258106887223	0.140643408885578
-TR1837|c2_g1_i1	wt_37	wt_GSNO	-2.70136949048315	8.19724487849862	0.11443273811818	0.184087448277072
-TR4859|c0_g1_i1	wt_37	wt_GSNO	1.06021338602227	9.44252758756623	0.17021260004507	0.262411091736149
-TR4084|c0_g1_i1	wt_37	wt_GSNO	-0.527027354857722	13.3333941866224	0.195100037539558	0.280916147575458
-TR1891|c0_g1_i1	wt_37	wt_GSNO	-0.481344817930584	13.5015018099629	0.197400536134106	0.280916147575458
-TR24|c0_g1_i1	wt_37	wt_GSNO	0.590686928315332	12.3882336221811	0.209814398393357	0.287523434835341
-TR2011|c5_g1_i1	wt_37	wt_GSNO	-0.668008806764204	9.63014074618193	0.239244885423374	0.316145027166602
-TR939|c0_g1_i1	wt_37	wt_GSNO	-0.361607139894815	13.0833886152319	0.340252678428006	0.434115486270215
-TR5075|c0_g1_i1	wt_37	wt_GSNO	0.617585416067661	10.4358029661318	0.377913209145196	0.466092957945741
-TR1492|c0_g1_i2	wt_37	wt_GSNO	0.0311900896664335	17.1368189470585	0.559289231968699	0.657620159615942
-TR3249|c0_g1_i1	wt_37	wt_GSNO	-0.894241538356016	8.33957569586088	0.568752570478653	0.657620159615942
-TR2278|c0_g1_i1	wt_37	wt_GSNO	-0.0373200220187202	15.4258149088647	0.636489077475997	0.713639268685208
-TR2182|c3_g2_i6	wt_37	wt_GSNO	0.714549920613349	8.45775163335771	0.790296098133788	0.860028106792652
-TR1982|c2_g1_i1	wt_37	wt_GSNO	-0.181275971858276	9.49467590956657	0.873422282667325	0.923332127391172
-TR1678|c0_g1_i1	wt_37	wt_GSNO	-0.476606391142577	7.93769527756871	1	1
-TR1122|c0_g1_i1	wt_37	wt_GSNO	0.0647357997613641	8.26206759454538	1	1
+TR131|c0_g1_i1	wt_37	wt_GSNO	-5.83642810105669	16.0393552039823	0	0
+TR4277|c0_g1_i1	wt_37	wt_GSNO	4.41398153332839	17.4536476715771	1.21637348346174e-303	2.25029094440421e-302
+TR3091|c0_g1_i1	wt_37	wt_GSNO	-4.45237397999856	14.0403314476332	9.11341318887913e-90	1.12398762662843e-88
+TR4761|c0_g1_i1	wt_37	wt_GSNO	2.92554296928641	16.3361450450387	3.69873891948914e-76	3.42133350052745e-75
+TR2487|c0_g1_i1	wt_37	wt_GSNO	-1.58730581845079	15.8893922467915	5.42826219868508e-69	4.01691402702696e-68
+TR3854|c0_g1_i1	wt_37	wt_GSNO	-0.756824867554791	17.5153344325941	9.93801411860139e-30	6.12844203980419e-29
+TR1479|c0_g1_i1	wt_37	wt_GSNO	-1.67125620463691	14.56103285356	1.52685095059931e-26	8.07049788173923e-26
+TR3788|c0_g1_i1	wt_37	wt_GSNO	-2.92384493547476	12.8707566447513	2.80716974025173e-26	1.29831600486643e-25
+TR3638|c0_g1_i1	wt_37	wt_GSNO	1.50400807132974	15.1071935803349	1.01131038761579e-25	4.15760937130936e-25
+TR2107|c1_g1_i1	wt_37	wt_GSNO	2.54917839024164	11.4899163098162	1.29813298421564e-11	4.80309204159787e-11
+TR2122|c0_g2_i2	wt_37	wt_GSNO	-0.904224916354351	13.8984660083514	5.12805835511887e-07	1.72489235581271e-06
+TR2672|c0_g1_i1	wt_37	wt_GSNO	2.7835273976316	10.2430082688313	1.09649323769354e-05	3.26428239781416e-05
+TR2844|c0_g1_i1	wt_37	wt_GSNO	-0.705628684062878	14.1849718403614	1.14691003166444e-05	3.26428239781416e-05
+TR127|c1_g1_i1	wt_37	wt_GSNO	3.25921752655672	9.85805490683478	4.65148368806407e-05	0.000122932068898836
+TR5212|c0_g1_i1	wt_37	wt_GSNO	-0.868846907645273	13.0312970321941	8.02549473297866e-05	0.000197962203413474
+TR4669|c0_g2_i1	wt_37	wt_GSNO	-10.5376618403783	13.0208222595793	0.000100983795793505	0.000233525027772479
+TR4163|c0_g1_i1	wt_37	wt_GSNO	0.419885302419972	14.7306501662725	0.000212062001530818	0.000461546709214134
+TR5055|c0_g2_i1	wt_37	wt_GSNO	1.89467947607274	10.6064557750525	0.000354706720299247	0.000729119369504007
+TR1894|c2_g1_i1	wt_37	wt_GSNO	1.89765713767963	9.93882107563394	0.00173125775949168	0.00337139668953643
+TR1449|c0_g1_i1	wt_37	wt_GSNO	0.634078352010786	13.7169577495829	0.00217137808425439	0.00401704945587062
+TR2779|c0_g1_i1	wt_37	wt_GSNO	-0.57033686484928	14.0677674303448	0.0111989371149329	0.0197314606310723
+TR1891|c0_g1_i1	wt_37	wt_GSNO	-0.481534755723158	13.501506224993	0.0143918226007056	0.0242044289193685
+TR3807|c0_g1_i1	wt_37	wt_GSNO	2.66618717222413	8.56454952883374	0.0190046641424073	0.0305727205769162
+TR24|c0_g1_i1	wt_37	wt_GSNO	0.595098414993735	12.3882263577198	0.0313658793311069	0.0483557306354564
+TR939|c0_g1_i1	wt_37	wt_GSNO	-0.361675208475799	13.0833927791152	0.0549150321214498	0.0812742475397457
+TR4084|c0_g1_i1	wt_37	wt_GSNO	-0.528091154047526	13.333398560375	0.0670751762392915	0.0954531354174533
+TR1837|c2_g1_i1	wt_37	wt_GSNO	-2.70993930289112	8.19725290476621	0.0887918514630023	0.121677722375225
+TR5075|c0_g1_i1	wt_37	wt_GSNO	0.614944173796075	10.4357920601168	0.162306513000849	0.214476463608265
+TR4859|c0_g1_i1	wt_37	wt_GSNO	1.05953644928152	9.44251782921817	0.174748084396246	0.222954452505555
+TR2011|c5_g1_i1	wt_37	wt_GSNO	-0.669059646383004	9.63015201113972	0.264703411652408	0.32646754103797
+TR1492|c0_g1_i2	wt_37	wt_GSNO	0.031711320644402	17.1368189355291	0.451877741421955	0.539337949439108
+TR3249|c0_g1_i1	wt_37	wt_GSNO	-0.891916586965799	8.33958255206055	0.564868681268914	0.653129412717181
+TR2278|c0_g1_i1	wt_37	wt_GSNO	-0.0377499361453361	15.4258150009092	0.736032464572516	0.825248520884336
+TR2182|c3_g2_i6	wt_37	wt_GSNO	0.715543556453753	8.45775004801063	0.789411909605702	0.859065901629735
+TR1982|c2_g1_i1	wt_37	wt_GSNO	-0.179857779984199	9.4946775424438	0.881459062505158	0.931828151791167
+TR1678|c0_g1_i1	wt_37	wt_GSNO	-0.501309819317686	7.93769570375269	1	1
+TR1122|c0_g1_i1	wt_37	wt_GSNO	0.0611166350434577	8.2620697940663	1	1
Binary file test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.edgeR.DE_results.MA_n_Volcano.pdf has changed
--- a/test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.voom.DE_results	Sun Dec 19 16:21:54 2021 +0000
+++ b/test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.voom.DE_results	Tue Apr 11 19:55:15 2023 +0000
@@ -1,38 +1,38 @@
 sampleA	sampleB	logFC	logCPM	PValue	FDR
-TR131|c0_g1_i1	wt_37	wt_GSNO	-5.82360148900389	16.1142242655408	6.54502972918692e-10	2.42166099979916e-08
-TR4277|c0_g1_i1	wt_37	wt_GSNO	4.41183386172098	17.3836256000268	1.7102544921365e-09	3.16397081045253e-08
-TR3091|c0_g1_i1	wt_37	wt_GSNO	-4.43700179801176	14.1203688767724	4.42033048679943e-08	5.45174093371929e-07
-TR2487|c0_g1_i1	wt_37	wt_GSNO	-1.58598083708684	15.9280757073272	7.01720228399608e-08	6.49091211269637e-07
-TR4761|c0_g1_i1	wt_37	wt_GSNO	2.92043321768346	16.2716301848411	5.72725934421127e-07	4.23817191471634e-06
-TR1479|c0_g1_i1	wt_37	wt_GSNO	-1.67738254434993	14.6016057367881	1.03919750932427e-06	5.8615543150164e-06
-TR3638|c0_g1_i1	wt_37	wt_GSNO	1.50288215872986	15.0600281889274	1.12469315856867e-06	5.8615543150164e-06
-TR3788|c0_g1_i1	wt_37	wt_GSNO	-2.93907650045598	12.9393872783943	2.35975448958169e-06	9.70121290161359e-06
-TR3854|c0_g1_i1	wt_37	wt_GSNO	-0.759397690410038	17.5353083640786	1.26736309513868e-06	5.8615543150164e-06
-TR2107|c1_g1_i1	wt_37	wt_GSNO	2.46233758474327	11.260249244859	0.000163907571391062	0.000551325467406299
-TR2122|c0_g2_i2	wt_37	wt_GSNO	-0.898543060702643	13.9151768182402	0.000124408949544541	0.000460313113314803
-TR2844|c0_g1_i1	wt_37	wt_GSNO	-0.712202725875737	14.1973066750225	0.000243984033514546	0.000752284103336518
-TR5212|c0_g1_i1	wt_37	wt_GSNO	-0.87701850957337	13.0391017777502	0.000473838954429694	0.00134861856260759
-TR4163|c0_g1_i1	wt_37	wt_GSNO	0.417694804483349	14.7107025605232	0.000805848497363634	0.00212974245731817
-TR2672|c0_g1_i1	wt_37	wt_GSNO	2.90562993555483	9.81450205355949	0.00822748279906008	0.0169120479758457
-TR1449|c0_g1_i1	wt_37	wt_GSNO	0.640011354440497	13.6755402195434	0.00227354555819909	0.00560807904355776
-TR127|c1_g1_i1	wt_37	wt_GSNO	3.09466453837236	9.33233275488244	0.00997545255499303	0.0184545872267371
-TR1894|c2_g1_i1	wt_37	wt_GSNO	1.8273232048322	9.47625819175118	0.0170307015491222	0.0286425435144327
-TR5055|c0_g2_i1	wt_37	wt_GSNO	1.79897959483123	10.2910629958573	0.0144290410083875	0.025422596062397
-TR939|c0_g1_i1	wt_37	wt_GSNO	-0.363394684962815	13.0708604932728	0.00579686595094712	0.0134052525115652
-TR1837|c2_g1_i1	wt_37	wt_GSNO	-2.21418127698954	7.02378849272624	0.0306005987832276	0.0471759231241425
-TR1891|c0_g1_i1	wt_37	wt_GSNO	-0.477062796219233	13.500309435849	0.00675073796972544	0.0146927826399907
-TR3807|c0_g1_i1	wt_37	wt_GSNO	1.91879773659378	7.35599058475032	0.0402625583382777	0.0572967176352414
-TR2779|c0_g1_i1	wt_37	wt_GSNO	-0.600036558858359	14.0748557225205	0.00991998269314111	0.0184545872267371
-TR24|c0_g1_i1	wt_37	wt_GSNO	0.588796779058576	12.310400953631	0.0185008090691583	0.0297621711112546
-TR4859|c0_g1_i1	wt_37	wt_GSNO	1.06036244689068	8.9138577436531	0.104550838513832	0.143273371296733
-TR4084|c0_g1_i1	wt_37	wt_GSNO	-0.567278869966665	13.330468891507	0.0372234219214301	0.0550906644437166
-TR2011|c5_g1_i1	wt_37	wt_GSNO	-0.789577978066661	9.33004998835934	0.161975973261362	0.206659000367944
+TR131|c0_g1_i1	wt_37	wt_GSNO	-5.82360148900389	16.1142242655408	6.54502972918681e-10	2.42166099979912e-08
+TR4277|c0_g1_i1	wt_37	wt_GSNO	4.41183386172098	17.3836256000268	1.71025449213644e-09	3.1639708104524e-08
+TR3091|c0_g1_i1	wt_37	wt_GSNO	-4.43700179801175	14.1203688767724	4.42033048679932e-08	5.45174093371916e-07
+TR2487|c0_g1_i1	wt_37	wt_GSNO	-1.58598083708684	15.9280757073272	7.01720228399587e-08	6.49091211269618e-07
+TR4761|c0_g1_i1	wt_37	wt_GSNO	2.92043321768345	16.2716301848411	5.72725934421077e-07	4.23817191471597e-06
+TR1479|c0_g1_i1	wt_37	wt_GSNO	-1.67738254434994	14.6016057367881	1.03919750932434e-06	5.86155431501655e-06
+TR3638|c0_g1_i1	wt_37	wt_GSNO	1.50288215872986	15.0600281889274	1.12469315856861e-06	5.86155431501655e-06
+TR3788|c0_g1_i1	wt_37	wt_GSNO	-2.93907650045598	12.9393872783943	2.35975448958161e-06	9.7012129016133e-06
+TR3854|c0_g1_i1	wt_37	wt_GSNO	-0.759397690410033	17.5353083640786	1.26736309513871e-06	5.86155431501655e-06
+TR2107|c1_g1_i1	wt_37	wt_GSNO	2.46233758474327	11.260249244859	0.000163907571391064	0.000551325467406306
+TR2122|c0_g2_i2	wt_37	wt_GSNO	-0.898543060702644	13.9151768182402	0.000124408949544541	0.000460313113314803
+TR2844|c0_g1_i1	wt_37	wt_GSNO	-0.712202725875737	14.1973066750225	0.000243984033514541	0.000752284103336501
+TR5212|c0_g1_i1	wt_37	wt_GSNO	-0.877018509573372	13.0391017777502	0.000473838954429683	0.00134861856260756
+TR4163|c0_g1_i1	wt_37	wt_GSNO	0.417694804483346	14.7107025605232	0.000805848497363675	0.00212974245731828
+TR2672|c0_g1_i1	wt_37	wt_GSNO	2.90562993555483	9.81450205355949	0.0082274827990601	0.0169120479758458
+TR1449|c0_g1_i1	wt_37	wt_GSNO	0.640011354440497	13.6755402195434	0.00227354555819906	0.00560807904355767
+TR127|c1_g1_i1	wt_37	wt_GSNO	3.09466453837236	9.33233275488244	0.00997545255499306	0.0184545872267372
+TR1894|c2_g1_i1	wt_37	wt_GSNO	1.82732320483219	9.47625819175118	0.0170307015491221	0.0286425435144326
+TR5055|c0_g2_i1	wt_37	wt_GSNO	1.79897959483123	10.2910629958573	0.0144290410083874	0.0254225960623969
+TR939|c0_g1_i1	wt_37	wt_GSNO	-0.363394684962811	13.0708604932728	0.00579686595094751	0.0134052525115661
+TR1837|c2_g1_i1	wt_37	wt_GSNO	-2.21418127698954	7.02378849272624	0.0306005987832277	0.0471759231241427
+TR1891|c0_g1_i1	wt_37	wt_GSNO	-0.477062796219235	13.500309435849	0.00675073796972539	0.0146927826399906
+TR3807|c0_g1_i1	wt_37	wt_GSNO	1.91879773659378	7.35599058475032	0.0402625583382779	0.0572967176352417
+TR2779|c0_g1_i1	wt_37	wt_GSNO	-0.600036558858356	14.0748557225205	0.0099199826931416	0.0184545872267372
+TR24|c0_g1_i1	wt_37	wt_GSNO	0.588796779058576	12.310400953631	0.0185008090691582	0.0297621711112545
+TR4859|c0_g1_i1	wt_37	wt_GSNO	1.06036244689069	8.9138577436531	0.104550838513831	0.143273371296732
+TR4084|c0_g1_i1	wt_37	wt_GSNO	-0.567278869966665	13.330468891507	0.03722342192143	0.0550906644437164
+TR2011|c5_g1_i1	wt_37	wt_GSNO	-0.78957797806666	9.33004998835934	0.161975973261362	0.206659000367945
 TR2182|c3_g2_i6	wt_37	wt_GSNO	1.02218394394404	7.37517597546907	0.329234058043314	0.406055338253421
-TR5075|c0_g1_i1	wt_37	wt_GSNO	0.549449880041588	10.1791103984097	0.127566698813275	0.168570280574684
-TR4669|c0_g2_i1	wt_37	wt_GSNO	-6.27345157840298	13.126293325041	0.423017017822531	0.489113426857301
-TR1678|c0_g1_i1	wt_37	wt_GSNO	-0.330222398445961	5.95523974949609	0.735881722270124	0.79829094077818
-TR1122|c0_g1_i1	wt_37	wt_GSNO	0.193564460109425	7.01613737702005	0.875819231521416	0.875819231521416
-TR3249|c0_g1_i1	wt_37	wt_GSNO	-0.276543877903423	7.32180296800742	0.776715509946338	0.79829094077818
-TR1982|c2_g1_i1	wt_37	wt_GSNO	-0.131251756802268	9.08566155151058	0.763275890632561	0.79829094077818
-TR2278|c0_g1_i1	wt_37	wt_GSNO	-0.0407242590322052	15.424279874284	0.616230913043451	0.69092556916993
-TR1492|c0_g1_i2	wt_37	wt_GSNO	0.0323916193661019	17.1363857315734	0.39613877470297	0.472810795613223
+TR5075|c0_g1_i1	wt_37	wt_GSNO	0.549449880041589	10.1791103984097	0.127566698813275	0.168570280574685
+TR4669|c0_g2_i1	wt_37	wt_GSNO	-6.27345157840299	13.126293325041	0.42301701782253	0.4891134268573
+TR1678|c0_g1_i1	wt_37	wt_GSNO	-0.330222398445961	5.95523974949609	0.735881722270124	0.798290940778181
+TR1122|c0_g1_i1	wt_37	wt_GSNO	0.193564460109423	7.01613737702005	0.875819231521417	0.875819231521417
+TR3249|c0_g1_i1	wt_37	wt_GSNO	-0.276543877903423	7.32180296800742	0.776715509946338	0.798290940778181
+TR1982|c2_g1_i1	wt_37	wt_GSNO	-0.131251756802266	9.08566155151058	0.763275890632564	0.798290940778181
+TR2278|c0_g1_i1	wt_37	wt_GSNO	-0.0407242590322026	15.424279874284	0.616230913043476	0.690925569169958
+TR1492|c0_g1_i2	wt_37	wt_GSNO	0.0323916193660987	17.1363857315734	0.39613877470302	0.472810795613282
Binary file test-data/count/exp_diff/input.matrix.wt_37_vs_wt_GSNO.voom.DE_results.MA_n_Volcano.pdf has changed
--- a/test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.DESeq2.DE_results	Sun Dec 19 16:21:54 2021 +0000
+++ b/test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.DESeq2.DE_results	Tue Apr 11 19:55:15 2023 +0000
@@ -1,39 +1,39 @@
 sampleA	sampleB	baseMeanA	baseMeanB	baseMean	log2FoldChange	lfcSE	stat	pvalue	padj
-TR4277|c0_g1_i1	wt_37	wt_ph8	4705.34614971641	162.902721493704	2434.12443560506	4.85332629705957	0.130960775627329	37.0593887659196	1.26787233139066e-300	4.81791485928452e-299
-TR131|c0_g1_i1	wt_37	wt_ph8	32.0461070493257	1436.30905989883	734.177583474076	-5.49708942597102	0.198466854292743	-27.6977707212645	7.42748041559505e-169	1.41122127896306e-167
-TR3091|c0_g1_i1	wt_37	wt_ph8	20.4914097091341	321.651020117047	171.071214913091	-3.98630633515117	0.247421953542878	-16.1113687693051	2.12272588309166e-58	2.47056970916163e-57
-TR4761|c0_g1_i1	wt_37	wt_ph8	2012.6141923276	384.620292965437	1198.61724264652	2.3876556238738	0.148312557773369	16.0988095662291	2.60059969385434e-58	2.47056970916163e-57
-TR5075|c0_g1_i1	wt_37	wt_ph8	19.3833722195684	136.98672801182	78.1850501156942	-2.81556781738656	0.271397918695418	-10.3743161735385	3.24527446090745e-25	2.46640859028966e-24
-TR2779|c0_g1_i1	wt_37	wt_ph8	191.51955185349	1058.15934185376	624.839446853626	-2.46872482043468	0.248047686960726	-9.95262181511717	2.45625242439133e-23	1.55562653544784e-22
-TR1891|c0_g1_i1	wt_37	wt_ph8	131.416087212132	376.595292171713	254.005689691923	-1.51763504949468	0.1638333296262	-9.26328637132193	1.98234808919548e-20	1.07613181984897e-19
-TR1492|c0_g1_i2	wt_37	wt_ph8	2006.11782336441	890.823502721036	1448.47066304272	1.17138763330801	0.12740597231583	9.19413440371721	3.78025797563847e-20	1.79562253842827e-19
-TR2487|c0_g1_i1	wt_37	wt_ph8	418.818667162757	965.862817209246	692.340742186001	-1.2068861494209	0.138672539999103	-8.70313725722989	3.22833072204789e-18	1.36307297153133e-17
-TR3638|c0_g1_i1	wt_37	wt_ph8	713.131183384274	326.063958913919	519.597571149096	1.12959116050602	0.141514345090045	7.98216717737888	1.43786102301427e-15	5.46387188745423e-15
-TR2122|c0_g2_i2	wt_37	wt_ph8	146.135958637131	360.821667264163	253.478812950647	-1.30611123021679	0.169971549866392	-7.68429323168187	1.53843927144304e-14	5.31460839225778e-14
-TR2107|c1_g1_i1	wt_37	wt_ph8	59.5986596731862	1.89840873462066	30.7485342039034	4.94663101068376	0.648801734442531	7.62425676148051	2.45444399373987e-14	7.77240598017624e-14
-TR1479|c0_g1_i1	wt_37	wt_ph8	158.005105094407	334.827472148091	246.416288621249	-1.08064044509537	0.1658526880096	-6.5156643408325	7.23686413447617e-11	2.11539105469303e-10
-TR24|c0_g1_i1	wt_37	wt_ph8	85.6614643869141	199.923709280262	142.792586833588	-1.2309601921531	0.197065470330035	-6.24645296860761	4.19878369504606e-10	1.13966986008393e-09
-TR4163|c0_g1_i1	wt_37	wt_ph8	424.593720981574	227.471218917767	326.03246994967	0.902378343080323	0.156120482680011	5.78001251078543	7.46950706226027e-09	1.89227512243927e-08
-TR1449|c0_g1_i1	wt_37	wt_ph8	220.782434528097	117.26089394399	169.021664236043	0.916182468982544	0.175267159439457	5.22734819182726	1.71958482582468e-07	4.0840139613336e-07
-TR2278|c0_g1_i1	wt_37	wt_ph8	594.657329919233	348.341653317169	471.499491618201	0.77372548280461	0.158144801146882	4.8925129197639	9.95565784679233e-07	2.22538234222417e-06
-TR5055|c0_g2_i1	wt_37	wt_ph8	28.6665933385886	6.05959103586122	17.3630921872249	2.22056293047175	0.515653625436263	4.30630722045843	1.66002467176804e-05	3.50449652928809e-05
-TR127|c1_g1_i1	wt_37	wt_ph8	16.3791628279609	1.58772512712498	8.98344397754296	3.35782864860774	0.805715621214412	4.16751091848842	3.07943766984562e-05	6.15887533969124e-05
-TR1894|c2_g1_i1	wt_37	wt_ph8	16.2826445742552	1.67571344127509	8.97917900776516	3.31835899440704	0.806156235895963	4.1162728099709	3.85048512190331e-05	7.31592173161629e-05
-TR2672|c0_g1_i1	wt_37	wt_ph8	22.3129914439134	7.89947501226409	15.1062332280887	1.4879160019133	0.490304786216723	3.03467566244728	0.00240794483755529	0.00435723351557623
-TR4084|c0_g1_i1	wt_37	wt_ph8	113.2594381118	173.837287636503	143.548362874151	-0.610546095515356	0.203809508378262	-2.99567032163292	0.00273842322103228	0.00473000374541939
-TR4859|c0_g1_i1	wt_37	wt_ph8	8.91205730249659	1.28188505334354	5.09697117792006	2.79846628921536	0.943303749490582	2.96666507551426	0.00301048704228202	0.00497384815681378
-TR1678|c0_g1_i1	wt_37	wt_ph8	0.738899982352077	7.85275634721875	4.29582816478541	-3.47431884008145	1.21198503063676	-2.8666351087324	0.00414861034620894	0.00656863304816415
-TR3807|c0_g1_i1	wt_37	wt_ph8	4.23896204531587	0.352255997713617	2.29560902151474	3.60257127355045	1.494771199452	2.41011552461754	0.0159474699414718	0.0242401543110371
-TR1859|c3_g1_i1	wt_37	wt_ph8	0.361569353912422	2.25550826604853	1.30853880998047	-2.58650633406891	1.68391965639604	-1.53600340980911	0.124537544060973	0.181135380859875
-TR3249|c0_g1_i1	wt_37	wt_ph8	1.36481976577862	4.37661229401476	2.87071602989669	-1.67837058189371	1.10474169040967	-1.51924254915312	0.12870145482149	0.181135380859875
-TR2090|c0_g1_i1	wt_37	wt_ph8	0	5.87877087384675	2.93938543692337	-4.93100736412614	3.57047444665656	-1.38105101655149	0.167263275059569	0.227000159009415
-TR1982|c2_g1_i1	wt_37	wt_ph8	7.00144976454503	11.520013112092	9.26073143831853	-0.727260398375603	0.567300823658434	-1.28196605406919	0.199854554547715	0.261878381821143
-TR1837|c2_g1_i1	wt_37	wt_ph8	0.377330628439655	1.67813520813222	1.02773291828594	-2.14007669057536	1.85335822648042	-1.15470212935543	0.248212427250959	0.314402407851215
-TR5212|c0_g1_i1	wt_37	wt_ph8	80.2050001877881	94.8352723753388	87.5201362815635	-0.236625075567938	0.21614403033503	-1.09475646956875	0.273623341840838	0.335409257740381
-TR3854|c0_g1_i1	wt_37	wt_ph8	1925.26464813324	2107.16376011081	2016.21420412203	-0.130625245556183	0.13088163358419	-0.998041069468758	0.318259444082768	0.377933089848287
-TR2844|c0_g1_i1	wt_37	wt_ph8	193.030766468894	213.82243412349	203.426600296192	-0.144061748535941	0.17173092225162	-0.838880654963596	0.401536284440308	0.450271927171228
-TR1122|c0_g1_i1	wt_37	wt_ph8	1.69354093201913	0.660517838352177	1.17702938518565	1.3946217378633	1.66721495733336	0.836497856337578	0.402874882205836	0.450271927171228
-TR2011|c5_g1_i1	wt_37	wt_ph8	6.84875389533898	4.81927837273561	5.8340161340373	0.48395696149425	0.739237535887472	0.654670438120067	0.512679962329315	0.556623959100399
-TR2182|c3_g2_i6	wt_37	wt_ph8	2.76248771922916	1.94482465855284	2.353656188891	0.516404389322083	1.10366040723297	0.467901526536393	0.63985501178297	0.675402512437579
-TR3788|c0_g1_i1	wt_37	wt_ph8	23.7579432209456	26.0024682525169	24.8802057367313	-0.125340757750783	0.352879389384874	-0.355194328490741	0.722444013290729	0.741969527163451
-TR939|c0_g1_i1	wt_37	wt_ph8	103.002135647151	102.820214322362	102.911174984756	0.000973457550309434	0.195891269167835	0.00496937691222674	0.996035027203904	0.996035027203904
+TR4277|c0_g1_i1	wt_37	wt_ph8	4705.34614971641	162.902721493704	2434.12443560506	4.85332629705957	0.130960775627329	37.0593887659196	1.26787233139334e-300	4.81791485929468e-299
+TR131|c0_g1_i1	wt_37	wt_ph8	32.0461070493257	1436.30905989883	734.177583474076	-5.49708942597102	0.198466854292742	-27.6977707212647	7.42748041554821e-169	1.41122127895416e-167
+TR3091|c0_g1_i1	wt_37	wt_ph8	20.4914097091341	321.651020117047	171.071214913091	-3.98630633515117	0.247421953542881	-16.1113687693049	2.12272588309764e-58	2.47056970915936e-57
+TR4761|c0_g1_i1	wt_37	wt_ph8	2012.6141923276	384.620292965437	1198.61724264652	2.38765562387381	0.148312557773368	16.0988095662291	2.60059969385195e-58	2.47056970915936e-57
+TR5075|c0_g1_i1	wt_37	wt_ph8	19.3833722195684	136.98672801182	78.1850501156942	-2.81556781738656	0.271397918695417	-10.3743161735385	3.2452744609063e-25	2.46640859028879e-24
+TR2779|c0_g1_i1	wt_37	wt_ph8	191.51955185349	1058.15934185376	624.839446853626	-2.46872482043468	0.248047686960726	-9.95262181511715	2.45625242439164e-23	1.55562653544804e-22
+TR1891|c0_g1_i1	wt_37	wt_ph8	131.416087212132	376.595292171713	254.005689691923	-1.51763504949468	0.163833329626194	-9.26328637132227	1.98234808918918e-20	1.07613181984555e-19
+TR1492|c0_g1_i2	wt_37	wt_ph8	2006.11782336441	890.823502721036	1448.47066304272	1.17138763330801	0.127405972315828	9.1941344037173	3.78025797563516e-20	1.7956225384267e-19
+TR2487|c0_g1_i1	wt_37	wt_ph8	418.818667162757	965.862817209246	692.340742186001	-1.2068861494209	0.138672539999103	-8.70313725722991	3.22833072204724e-18	1.36307297153106e-17
+TR3638|c0_g1_i1	wt_37	wt_ph8	713.131183384274	326.063958913919	519.597571149096	1.12959116050603	0.141514345090043	7.98216717737901	1.43786102301281e-15	5.46387188744868e-15
+TR2122|c0_g2_i2	wt_37	wt_ph8	146.135958637131	360.821667264163	253.478812950647	-1.30611123021679	0.169971549866391	-7.68429323168191	1.53843927144259e-14	5.31460839225623e-14
+TR2107|c1_g1_i1	wt_37	wt_ph8	59.5986596731862	1.89840873462066	30.7485342039034	4.94663101068376	0.648801734442532	7.62425676148051	2.45444399374e-14	7.77240598017667e-14
+TR1479|c0_g1_i1	wt_37	wt_ph8	158.005105094407	334.827472148091	246.416288621249	-1.08064044509537	0.165852688009601	-6.51566434083244	7.23686413447896e-11	2.11539105469385e-10
+TR24|c0_g1_i1	wt_37	wt_ph8	85.6614643869141	199.923709280262	142.792586833588	-1.2309601921531	0.197065470330034	-6.24645296860764	4.19878369504523e-10	1.1396698600837e-09
+TR4163|c0_g1_i1	wt_37	wt_ph8	424.593720981574	227.471218917767	326.03246994967	0.902378343080325	0.156120482680009	5.7800125107855	7.46950706225728e-09	1.89227512243851e-08
+TR1449|c0_g1_i1	wt_37	wt_ph8	220.782434528097	117.26089394399	169.021664236043	0.916182468982546	0.175267159439456	5.22734819182728	1.71958482582447e-07	4.08401396133312e-07
+TR2278|c0_g1_i1	wt_37	wt_ph8	594.657329919233	348.341653317169	471.499491618201	0.773725482804612	0.158144801146882	4.8925129197639	9.95565784679224e-07	2.22538234222415e-06
+TR5055|c0_g2_i1	wt_37	wt_ph8	28.6665933385886	6.05959103586122	17.3630921872249	2.22056293047174	0.515653625436262	4.30630722045843	1.66002467176799e-05	3.50449652928799e-05
+TR127|c1_g1_i1	wt_37	wt_ph8	16.3791628279609	1.58772512712498	8.98344397754296	3.35782864860774	0.805715621214412	4.16751091848842	3.0794376698456e-05	6.15887533969119e-05
+TR1894|c2_g1_i1	wt_37	wt_ph8	16.2826445742552	1.67571344127509	8.97917900776516	3.31835899440704	0.806156235895962	4.1162728099709	3.85048512190321e-05	7.31592173161609e-05
+TR2672|c0_g1_i1	wt_37	wt_ph8	22.3129914439134	7.89947501226409	15.1062332280887	1.4879160019133	0.490304786216721	3.03467566244728	0.00240794483755522	0.00435723351557611
+TR4084|c0_g1_i1	wt_37	wt_ph8	113.2594381118	173.837287636503	143.548362874151	-0.610546095515353	0.203809508378262	-2.99567032163291	0.0027384232210324	0.0047300037454196
+TR4859|c0_g1_i1	wt_37	wt_ph8	8.91205730249659	1.28188505334354	5.09697117792006	2.79846628921536	0.94330374949058	2.96666507551426	0.00301048704228199	0.00497384815681373
+TR1678|c0_g1_i1	wt_37	wt_ph8	0.738899982352077	7.85275634721875	4.29582816478541	-3.47431884008145	1.21198503063676	-2.8666351087324	0.00414861034620891	0.00656863304816411
+TR3807|c0_g1_i1	wt_37	wt_ph8	4.23896204531587	0.352255997713617	2.29560902151474	3.60257127355045	1.494771199452	2.41011552461755	0.0159474699414716	0.0242401543110368
+TR1859|c3_g1_i1	wt_37	wt_ph8	0.361569353912422	2.25550826604853	1.30853880998047	-2.58650633406891	1.68391965639604	-1.53600340980911	0.124537544060973	0.181135380859874
+TR3249|c0_g1_i1	wt_37	wt_ph8	1.36481976577862	4.37661229401476	2.87071602989669	-1.67837058189371	1.10474169040967	-1.51924254915312	0.128701454821489	0.181135380859874
+TR2090|c0_g1_i1	wt_37	wt_ph8	0	5.87877087384675	2.93938543692337	-4.93100736412615	3.57047444665656	-1.38105101655149	0.167263275059569	0.227000159009415
+TR1982|c2_g1_i1	wt_37	wt_ph8	7.00144976454503	11.520013112092	9.26073143831853	-0.727260398375605	0.567300823658433	-1.28196605406919	0.199854554547713	0.261878381821141
+TR1837|c2_g1_i1	wt_37	wt_ph8	0.377330628439655	1.67813520813222	1.02773291828594	-2.14007669057536	1.85335822648042	-1.15470212935544	0.248212427250958	0.314402407851213
+TR5212|c0_g1_i1	wt_37	wt_ph8	80.2050001877881	94.8352723753388	87.5201362815635	-0.236625075567937	0.216144030335029	-1.09475646956875	0.273623341840839	0.335409257740383
+TR3854|c0_g1_i1	wt_37	wt_ph8	1925.26464813324	2107.16376011081	2016.21420412203	-0.130625245556186	0.130881633584188	-0.998041069468797	0.318259444082749	0.377933089848265
+TR2844|c0_g1_i1	wt_37	wt_ph8	193.030766468894	213.82243412349	203.426600296192	-0.144061748535941	0.171730922251619	-0.838880654963595	0.401536284440309	0.450271927171227
+TR1122|c0_g1_i1	wt_37	wt_ph8	1.69354093201913	0.660517838352177	1.17702938518565	1.39462173786331	1.66721495733336	0.83649785633758	0.402874882205835	0.450271927171227
+TR2011|c5_g1_i1	wt_37	wt_ph8	6.84875389533898	4.81927837273561	5.8340161340373	0.483956961494249	0.73923753588747	0.654670438120068	0.512679962329314	0.556623959100398
+TR2182|c3_g2_i6	wt_37	wt_ph8	2.76248771922916	1.94482465855284	2.353656188891	0.516404389322082	1.10366040723296	0.467901526536394	0.639855011782969	0.675402512437579
+TR3788|c0_g1_i1	wt_37	wt_ph8	23.7579432209456	26.0024682525169	24.8802057367313	-0.125340757750782	0.352879389384873	-0.35519432849074	0.72244401329073	0.741969527163452
+TR939|c0_g1_i1	wt_37	wt_ph8	103.002135647151	102.820214322362	102.911174984756	0.000973457550311695	0.195891269167832	0.00496937691223835	0.996035027203895	0.996035027203895
Binary file test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.DESeq2.DE_results.MA_n_Volcano.pdf has changed
--- a/test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.edgeR.DE_results	Sun Dec 19 16:21:54 2021 +0000
+++ b/test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.edgeR.DE_results	Tue Apr 11 19:55:15 2023 +0000
@@ -1,39 +1,39 @@
 sampleA	sampleB	logFC	logCPM	PValue	FDR
-TR131|c0_g1_i1	wt_37	wt_ph8	-5.83867709149149	16.0447742820606	3.67956255674e-64	1.3982337715612e-62
-TR3091|c0_g1_i1	wt_37	wt_ph8	-4.35104356420213	13.9337836495047	7.47918124727105e-59	1.4210444369815e-57
-TR4277|c0_g1_i1	wt_37	wt_ph8	4.51249642920563	17.4585638169146	1.30305812944242e-53	1.65054029729373e-52
-TR5075|c0_g1_i1	wt_37	wt_ph8	-3.18286810352713	12.8084040893566	8.25600206225396e-24	7.84320195914126e-23
-TR2107|c1_g1_i1	wt_37	wt_ph8	4.48477961203985	11.2510359028096	1.80754966502889e-22	1.37373774542196e-21
-TR2779|c0_g1_i1	wt_37	wt_ph8	-2.75442228103487	15.7797198210508	8.23352696880425e-15	5.21456708024269e-14
-TR1891|c0_g1_i1	wt_37	wt_ph8	-1.85607282303223	14.4424161372431	4.82341414399837e-12	2.61842482102769e-11
-TR4761|c0_g1_i1	wt_37	wt_ph8	2.05815692521639	16.4916266891202	6.53530817860542e-12	3.10427138483757e-11
-TR1479|c0_g1_i1	wt_37	wt_ph8	-1.43256512308186	14.3771181295432	1.13197856555697e-09	4.77946505457389e-09
-TR2122|c0_g2_i2	wt_37	wt_ph8	-1.63807722824331	14.4300672231344	2.54380104198531e-09	9.66644395954419e-09
-TR24|c0_g1_i1	wt_37	wt_ph8	-1.56169455062581	13.613754007054	1.01137959952142e-08	3.49385679834671e-08
-TR2487|c0_g1_i1	wt_37	wt_ph8	-1.52157644373511	15.8810635663776	2.37540305111961e-07	7.52210966187877e-07
-TR4084|c0_g1_i1	wt_37	wt_ph8	-0.991060679215133	13.5661427311877	4.21767858359174e-07	1.23285989366528e-06
-TR1678|c0_g1_i1	wt_37	wt_ph8	-3.62458577193226	9.02581543875671	1.43837087677047e-05	3.90414952266271e-05
-TR127|c1_g1_i1	wt_37	wt_ph8	2.90111481011278	9.73961125813442	2.21824302925283e-05	5.61954900744051e-05
-TR1894|c2_g1_i1	wt_37	wt_ph8	2.85359093751189	9.70265145133598	3.82707393478771e-05	9.08930059512081e-05
-TR5055|c0_g2_i1	wt_37	wt_ph8	1.8545312748531	10.5508309427169	0.000561739096452478	0.0012556520979526
-TR2090|c0_g1_i1	wt_37	wt_ph8	-5.85461418677349	8.72713197001274	0.000625444406369261	0.00132038263566844
-TR4859|c0_g1_i1	wt_37	wt_ph8	2.31469487039419	9.12085022188999	0.00236706272759891	0.00473412545519782
-TR1492|c0_g1_i2	wt_37	wt_ph8	0.847097868783511	16.8160271449712	0.00265383515294934	0.00504228679060374
-TR3638|c0_g1_i1	wt_37	wt_ph8	0.812580107843708	15.3469752226999	0.00403607816905259	0.00730337954399992
-TR3807|c0_g1_i1	wt_37	wt_ph8	2.92018331334326	8.37863764275674	0.0119536481076316	0.0206472103677272
-TR1449|c0_g1_i1	wt_37	wt_ph8	0.576747771663695	13.7363876885022	0.0130185393324759	0.0215088910710471
-TR1982|c2_g1_i1	wt_37	wt_ph8	-1.11743546508384	9.86122459596308	0.024471659211255	0.0382656346855499
-TR2672|c0_g1_i1	wt_37	wt_ph8	1.09825528852042	10.4080374441724	0.025174759661546	0.0382656346855499
-TR3249|c0_g1_i1	wt_37	wt_ph8	-2.00776956676821	8.66772655901099	0.0275363688345113	0.0402454621427472
-TR5212|c0_g1_i1	wt_37	wt_ph8	-0.582012857882519	12.8600915149255	0.0318599127004672	0.0448398771339909
-TR4163|c0_g1_i1	wt_37	wt_ph8	0.585935901552979	14.6858409740027	0.0333717283041774	0.0452902026985264
-TR2844|c0_g1_i1	wt_37	wt_ph8	-0.484938504762758	14.0537413817093	0.0410237194953782	0.0537552186491163
-TR1859|c3_g1_i1	wt_37	wt_ph8	-2.64648031785777	8.0811923384908	0.0677782555815868	0.0858524570700099
-TR2278|c0_g1_i1	wt_37	wt_ph8	0.462893051132405	15.2205527935145	0.0990317248813937	0.121393727273966
-TR3854|c0_g1_i1	wt_37	wt_ph8	-0.45233145936844	17.3656486469949	0.115995274036176	0.13774438791796
-TR3788|c0_g1_i1	wt_37	wt_ph8	-0.512277745155381	11.1125640718165	0.129462204245195	0.149077689736891
-TR939|c0_g1_i1	wt_37	wt_ph8	-0.343195417039388	13.0829763503018	0.196684960972624	0.219824368145874
-TR1837|c2_g1_i1	wt_37	wt_ph8	-2.21076601464763	7.9226544260522	0.248563909756302	0.269869387735413
-TR1122|c0_g1_i1	wt_37	wt_ph8	0.860567840252952	7.98418712954456	0.72405804618472	0.764283493194982
-TR2011|c5_g1_i1	wt_37	wt_ph8	0.075980865610854	9.27931055760989	0.901508002533997	0.925873083683564
-TR2182|c3_g2_i6	wt_37	wt_ph8	0.147124070779728	8.45393312498213	1	1
+TR131|c0_g1_i1	wt_37	wt_ph8	-5.84041934032622	16.0447738584896	2.64843647765193e-68	1.00640586150773e-66
+TR4277|c0_g1_i1	wt_37	wt_ph8	4.51251378503982	17.458563860849	7.87456958793119e-51	1.49616822170693e-49
+TR3091|c0_g1_i1	wt_37	wt_ph8	-4.33866462808288	13.9337820695818	2.36438873567113e-40	2.99489239851676e-39
+TR5075|c0_g1_i1	wt_37	wt_ph8	-3.18184004176717	12.8084012906916	4.32969562983877e-23	4.11321084834683e-22
+TR2779|c0_g1_i1	wt_37	wt_ph8	-2.76000097034818	15.7797193517192	7.02929665566158e-23	5.3422654583028e-22
+TR2107|c1_g1_i1	wt_37	wt_ph8	4.48695752844007	11.251039090086	2.85694633276303e-20	1.80939934408325e-19
+TR4761|c0_g1_i1	wt_37	wt_ph8	2.0579616780365	16.4916266757798	1.87157355154512e-14	1.01599707083878e-13
+TR1891|c0_g1_i1	wt_37	wt_ph8	-1.85558303182422	14.4424152648443	1.3549609315801e-11	6.43606442500547e-11
+TR2122|c0_g2_i2	wt_37	wt_ph8	-1.63829756449903	14.4300663727902	1.82580551883595e-09	7.70895663508514e-09
+TR2487|c0_g1_i1	wt_37	wt_ph8	-1.52256386898699	15.8810632159828	1.00076368146348e-08	3.80290198956123e-08
+TR24|c0_g1_i1	wt_37	wt_ph8	-1.56069263322937	13.6137525216945	2.0641918619938e-08	7.13084461416041e-08
+TR1479|c0_g1_i1	wt_37	wt_ph8	-1.43017641947686	14.3771173732228	1.25129096758536e-07	3.96242139735364e-07
+TR127|c1_g1_i1	wt_37	wt_ph8	2.89378247411933	9.73961391632741	1.77483025831263e-06	5.18796537045229e-06
+TR1894|c2_g1_i1	wt_37	wt_ph8	2.84455594181396	9.70265363738305	3.80774768997069e-06	1.03353151584919e-05
+TR2090|c0_g1_i1	wt_37	wt_ph8	-5.84865009980137	8.72712853989006	7.1017296397318e-06	1.79910484206539e-05
+TR5055|c0_g2_i1	wt_37	wt_ph8	1.82971910256975	10.5508300754678	1.05374662314498e-05	2.50264822996933e-05
+TR1678|c0_g1_i1	wt_37	wt_ph8	-3.62297933758159	9.02581162405914	1.85386281004691e-05	4.1439286342225e-05
+TR4084|c0_g1_i1	wt_37	wt_ph8	-0.989047817791601	13.5661419902701	0.000266385708775898	0.000562369829638008
+TR1492|c0_g1_i2	wt_37	wt_ph8	0.846946606328173	16.816027085378	0.00111844437365923	0.00223688874731846
+TR4859|c0_g1_i1	wt_37	wt_ph8	2.31297110196869	9.12085217163192	0.00169405620519211	0.00321870678986502
+TR3638|c0_g1_i1	wt_37	wt_ph8	0.812150684296427	15.3469750288171	0.00195862604708162	0.0035441804661477
+TR3807|c0_g1_i1	wt_37	wt_ph8	2.91885642490418	8.37863917696072	0.00889981242694952	0.0153724032829128
+TR2672|c0_g1_i1	wt_37	wt_ph8	1.09015105073495	10.4080380170218	0.0113968048117331	0.0188295036019939
+TR3249|c0_g1_i1	wt_37	wt_ph8	-2.00248923602224	8.66772464596919	0.012175839230813	0.0192784121154539
+TR1982|c2_g1_i1	wt_37	wt_ph8	-1.11692146946545	9.86122186982139	0.0254732500230551	0.0380540735981811
+TR4163|c0_g1_i1	wt_37	wt_ph8	0.585493536631111	14.6858406628863	0.0260369977250713	0.0380540735981811
+TR1449|c0_g1_i1	wt_37	wt_ph8	0.579397661518319	13.7363873307119	0.0302958377959148	0.0426385865275838
+TR5212|c0_g1_i1	wt_37	wt_ph8	-0.580254103150409	12.8600901680646	0.0404390149604427	0.054881520303458
+TR1859|c3_g1_i1	wt_37	wt_ph8	-2.66753302288967	8.08119047667972	0.0460728591095077	0.0603713326262514
+TR2844|c0_g1_i1	wt_37	wt_ph8	-0.482774572490911	14.0537407448782	0.0727694305006538	0.0921746119674948
+TR2278|c0_g1_i1	wt_37	wt_ph8	0.462415658712107	15.2205525577595	0.0767838146787893	0.0941220954127095
+TR3854|c0_g1_i1	wt_37	wt_ph8	-0.452545415035422	17.3656485551494	0.080313088818483	0.0953717929719486
+TR3788|c0_g1_i1	wt_37	wt_ph8	-0.50904223856954	11.112562271961	0.177982574706024	0.204949631479664
+TR1837|c2_g1_i1	wt_37	wt_ph8	-2.21377059210539	7.92265348832559	0.23010293924542	0.251432947894972
+TR939|c0_g1_i1	wt_37	wt_ph8	-0.340377492720978	13.0829751506545	0.231582978324316	0.251432947894972
+TR1122|c0_g1_i1	wt_37	wt_ph8	0.90037398238529	7.98418851125693	0.694931998823269	0.733539332091228
+TR2182|c3_g2_i6	wt_37	wt_ph8	0.125015386728524	8.45393207220823	0.999999999999999	1
+TR2011|c5_g1_i1	wt_37	wt_ph8	0.0588147623425484	9.27930953984144	1	1
Binary file test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.edgeR.DE_results.MA_n_Volcano.pdf has changed
--- a/test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.voom.DE_results	Sun Dec 19 16:21:54 2021 +0000
+++ b/test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.voom.DE_results	Tue Apr 11 19:55:15 2023 +0000
@@ -1,39 +1,39 @@
 sampleA	sampleB	logFC	logCPM	PValue	FDR
-TR131|c0_g1_i1	wt_37	wt_ph8	-5.89108692370307	16.0946870940125	5.83734002581789e-38	2.2181892098108e-36
-TR4277|c0_g1_i1	wt_37	wt_ph8	4.47812345668175	17.3786096664403	2.84916418820701e-34	5.41341195759331e-33
-TR3091|c0_g1_i1	wt_37	wt_ph8	-4.37454375877296	13.9751350003907	3.03684158911717e-24	3.84666601288175e-23
-TR2779|c0_g1_i1	wt_37	wt_ph8	-2.89398117484377	15.8061264352363	2.71183962208552e-19	2.57624764098124e-18
-TR5075|c0_g1_i1	wt_37	wt_ph8	-3.21512246000432	12.8334153580766	2.25968184332879e-15	1.71735820092988e-14
-TR2107|c1_g1_i1	wt_37	wt_ph8	4.32040270723487	11.0762608486921	1.80270537224079e-11	1.14171340241917e-10
-TR4761|c0_g1_i1	wt_37	wt_ph8	2.00464775189483	16.4172477083723	4.47039820077749e-11	2.42678759470778e-10
-TR1891|c0_g1_i1	wt_37	wt_ph8	-1.89490003648365	14.4620196202787	2.60196088184267e-10	1.23593141887527e-09
-TR2122|c0_g2_i2	wt_37	wt_ph8	-1.68823123696301	14.4430864744705	9.44150971333403e-09	3.98641521229659e-08
-TR24|c0_g1_i1	wt_37	wt_ph8	-1.665273448047	13.6146325155501	3.81691570216026e-08	1.4504279668209e-07
-TR2487|c0_g1_i1	wt_37	wt_ph8	-1.57111929409713	15.8914511338271	9.80135417366341e-08	3.3859223509019e-07
-TR1479|c0_g1_i1	wt_37	wt_ph8	-1.45195340320994	14.3929474544484	4.87972014978913e-07	1.54524471409989e-06
-TR1678|c0_g1_i1	wt_37	wt_ph8	-3.32711159096413	8.62991286220581	2.09660385386406e-05	6.12853434206418e-05
-TR127|c1_g1_i1	wt_37	wt_ph8	2.68488776770857	9.36026180000128	7.01712501052362e-05	0.000190464821714212
-TR1894|c2_g1_i1	wt_37	wt_ph8	2.65840371977461	9.30640094015976	8.26981533784737e-05	0.0002095019885588
-TR2090|c0_g1_i1	wt_37	wt_ph8	-3.12073361486577	8.21515298661506	0.000232532921389064	0.000552265688299028
-TR5055|c0_g2_i1	wt_37	wt_ph8	1.75449782198233	10.3047459168783	0.000592147419555538	0.00125008899683947
-TR4084|c0_g1_i1	wt_37	wt_ph8	-0.990738086664283	13.5812840323914	0.000555059638311732	0.00124072154446152
-TR4859|c0_g1_i1	wt_37	wt_ph8	2.03844841522755	8.5557148387818	0.00395651243262557	0.00791302486525114
-TR3807|c0_g1_i1	wt_37	wt_ph8	2.27805436961797	7.32408068149202	0.00589866928719914	0.0106737825196937
-TR1492|c0_g1_i2	wt_37	wt_ph8	0.80292474159496	16.7717103141256	0.00563666782754467	0.0106737825196937
-TR1859|c3_g1_i1	wt_37	wt_ph8	-2.08358066039446	6.92308482511994	0.0165122223690091	0.0272810630444498
-TR3638|c0_g1_i1	wt_37	wt_ph8	0.765536214533451	15.2959378061905	0.00664915219564581	0.0114848992470246
-TR2672|c0_g1_i1	wt_37	wt_ph8	1.15555384827173	10.1973122527932	0.0181178874953213	0.0286866552009254
-TR3249|c0_g1_i1	wt_37	wt_ph8	-1.48866796495104	8.06119288435276	0.0485882100928285	0.065758173656721
-TR1982|c2_g1_i1	wt_37	wt_ph8	-1.06368641289493	9.64628067316551	0.0416733207176468	0.0609071610488684
+TR131|c0_g1_i1	wt_37	wt_ph8	-5.89108692370307	16.0946870940125	5.83734002581822e-38	2.21818920981092e-36
+TR4277|c0_g1_i1	wt_37	wt_ph8	4.47812345668175	17.3786096664403	2.84916418820709e-34	5.41341195759347e-33
+TR3091|c0_g1_i1	wt_37	wt_ph8	-4.37454375877296	13.9751350003907	3.03684158911758e-24	3.84666601288227e-23
+TR2779|c0_g1_i1	wt_37	wt_ph8	-2.89398117484377	15.8061264352363	2.71183962208562e-19	2.57624764098134e-18
+TR5075|c0_g1_i1	wt_37	wt_ph8	-3.21512246000432	12.8334153580766	2.25968184332891e-15	1.71735820092997e-14
+TR2107|c1_g1_i1	wt_37	wt_ph8	4.32040270723487	11.0762608486921	1.80270537224084e-11	1.1417134024192e-10
+TR4761|c0_g1_i1	wt_37	wt_ph8	2.00464775189483	16.4172477083723	4.47039820077757e-11	2.42678759470782e-10
+TR1891|c0_g1_i1	wt_37	wt_ph8	-1.89490003648365	14.4620196202787	2.6019608818427e-10	1.23593141887528e-09
+TR2122|c0_g2_i2	wt_37	wt_ph8	-1.68823123696301	14.4430864744705	9.44150971333414e-09	3.98641521229664e-08
+TR24|c0_g1_i1	wt_37	wt_ph8	-1.665273448047	13.6146325155501	3.81691570216034e-08	1.45042796682093e-07
+TR2487|c0_g1_i1	wt_37	wt_ph8	-1.57111929409714	15.8914511338271	9.80135417366337e-08	3.38592235090189e-07
+TR1479|c0_g1_i1	wt_37	wt_ph8	-1.45195340320994	14.3929474544484	4.87972014978926e-07	1.54524471409993e-06
+TR1678|c0_g1_i1	wt_37	wt_ph8	-3.32711159096413	8.62991286220581	2.09660385386408e-05	6.12853434206423e-05
+TR127|c1_g1_i1	wt_37	wt_ph8	2.68488776770857	9.36026180000128	7.01712501052367e-05	0.000190464821714214
+TR1894|c2_g1_i1	wt_37	wt_ph8	2.65840371977461	9.30640094015976	8.26981533784744e-05	0.000209501988558802
+TR2090|c0_g1_i1	wt_37	wt_ph8	-3.12073361486577	8.21515298661506	0.000232532921389067	0.000552265688299035
+TR5055|c0_g2_i1	wt_37	wt_ph8	1.75449782198233	10.3047459168783	0.000592147419555542	0.00125008899683948
+TR4084|c0_g1_i1	wt_37	wt_ph8	-0.990738086664284	13.5812840323914	0.000555059638311732	0.00124072154446152
+TR4859|c0_g1_i1	wt_37	wt_ph8	2.03844841522755	8.5557148387818	0.00395651243262561	0.00791302486525122
+TR3807|c0_g1_i1	wt_37	wt_ph8	2.27805436961797	7.32408068149202	0.00589866928719915	0.0106737825196937
+TR1492|c0_g1_i2	wt_37	wt_ph8	0.802924741594956	16.7717103141256	0.00563666782754487	0.0106737825196937
+TR1859|c3_g1_i1	wt_37	wt_ph8	-2.08358066039446	6.92308482511994	0.016512222369009	0.0272810630444497
+TR3638|c0_g1_i1	wt_37	wt_ph8	0.765536214533451	15.2959378061905	0.00664915219564584	0.0114848992470246
+TR2672|c0_g1_i1	wt_37	wt_ph8	1.15555384827173	10.1973122527932	0.0181178874953214	0.0286866552009255
+TR3249|c0_g1_i1	wt_37	wt_ph8	-1.48866796495104	8.06119288435276	0.0485882100928286	0.0657581736567205
+TR1982|c2_g1_i1	wt_37	wt_ph8	-1.06368641289493	9.64628067316551	0.0416733207176469	0.0609071610488685
 TR1837|c2_g1_i1	wt_37	wt_ph8	-1.43890969571076	6.48444225997254	0.11393330230991	0.135295796493019
-TR5212|c0_g1_i1	wt_37	wt_ph8	-0.63168831011067	12.8380836623566	0.0369371606978983	0.0561444842608054
-TR4163|c0_g1_i1	wt_37	wt_ph8	0.545743678134199	14.6411189904126	0.0480591953597162	0.065758173656721
-TR1449|c0_g1_i1	wt_37	wt_ph8	0.549932747054717	13.6939664483469	0.0501838693696029	0.065758173656721
-TR2844|c0_g1_i1	wt_37	wt_ph8	-0.508967050135572	14.0451022220879	0.0631262591502691	0.0799599282570075
-TR3854|c0_g1_i1	wt_37	wt_ph8	-0.504473372285636	17.3527799714624	0.0818779321593283	0.100366497485628
-TR1122|c0_g1_i1	wt_37	wt_ph8	0.501746583160273	6.50836597017328	0.579206371120405	0.611384502849316
+TR5212|c0_g1_i1	wt_37	wt_ph8	-0.63168831011067	12.8380836623566	0.0369371606978984	0.0561444842608055
+TR4163|c0_g1_i1	wt_37	wt_ph8	0.545743678134199	14.6411189904126	0.0480591953597163	0.0657581736567205
+TR1449|c0_g1_i1	wt_37	wt_ph8	0.549932747054718	13.6939664483469	0.0501838693696025	0.0657581736567205
+TR2844|c0_g1_i1	wt_37	wt_ph8	-0.508967050135572	14.0451022220879	0.0631262591502692	0.0799599282570077
+TR3854|c0_g1_i1	wt_37	wt_ph8	-0.504473372285636	17.3527799714624	0.0818779321593284	0.100366497485628
+TR1122|c0_g1_i1	wt_37	wt_ph8	0.501746583160273	6.50836597017328	0.579206371120405	0.611384502849317
 TR3788|c0_g1_i1	wt_37	wt_ph8	-0.524753873079964	11.0311382344715	0.196342217213272	0.213171550117267
-TR2278|c0_g1_i1	wt_37	wt_ph8	0.424377145183038	15.1829447141358	0.128541258915261	0.148017207235755
+TR2278|c0_g1_i1	wt_37	wt_ph8	0.424377145183046	15.1829447141358	0.128541258915254	0.148017207235747
 TR2182|c3_g2_i6	wt_37	wt_ph8	-0.0429471548350905	7.57134083040984	0.954463369529891	0.954463369529891
 TR939|c0_g1_i1	wt_37	wt_ph8	-0.398499350568058	13.0523653134109	0.173205070507278	0.193582137625782
 TR2011|c5_g1_i1	wt_37	wt_ph8	-0.0410416962762211	8.85697121679121	0.94542366790428	0.954463369529891
Binary file test-data/count/exp_diff/input.matrix.wt_37_vs_wt_ph8.voom.DE_results.MA_n_Volcano.pdf has changed
--- a/test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.DESeq2.DE_results	Sun Dec 19 16:21:54 2021 +0000
+++ b/test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.DESeq2.DE_results	Tue Apr 11 19:55:15 2023 +0000
@@ -1,40 +1,40 @@
 sampleA	sampleB	baseMeanA	baseMeanB	baseMean	log2FoldChange	lfcSE	stat	pvalue	padj
-TR2779|c0_g1_i1	wt_GSNO	wt_ph8	195.849684476753	966.924129135581	581.386906806167	-2.30255444666643	0.142496869452374	-16.1586318037394	9.87286349195067e-59	3.65295949202175e-57
-TR1891|c0_g1_i1	wt_GSNO	wt_ph8	128.246229498835	343.028289972482	235.637259735659	-1.41742353970608	0.104322254921725	-13.5869718380762	4.7847024102546e-42	8.85169945897101e-41
-TR4761|c0_g1_i1	wt_GSNO	wt_ph8	184.029205648389	351.782300021135	267.905752834762	-0.941259207260894	0.0933372308442124	-10.0844989587481	6.46943903995441e-24	7.97897481594377e-23
-TR24|c0_g1_i1	wt_GSNO	wt_ph8	39.3724575919554	183.288101009647	111.330279300801	-2.22846767043702	0.242443002218043	-9.19171784728532	3.8661704482204e-20	3.57620766460387e-19
-TR3638|c0_g1_i1	wt_GSNO	wt_ph8	174.266398355818	297.555274221606	235.910836288712	-0.761689698593786	0.0969314803260852	-7.85802193499368	3.90246977317854e-15	2.88782763215212e-14
-TR2122|c0_g2_i2	wt_GSNO	wt_ph8	190.673533226329	328.707071692642	259.690302459485	-0.789061688115738	0.103094089827306	-7.65380139091878	1.95123561208803e-14	1.20326196078762e-13
-TR4669|c0_g2_i1	wt_GSNO	wt_ph8	165.630009730314	0	82.8150048651569	9.98638581786287	2.4059110197361	4.15077105343582	3.31357095211564e-05	0.000175145893183255
-TR2278|c0_g1_i1	wt_GSNO	wt_ph8	426.804298570637	315.99710709695	371.400702833793	0.433055347501052	0.106340324733669	4.07235306630524	4.65405596936774e-05	0.000215250088583258
-TR4084|c0_g1_i1	wt_GSNO	wt_ph8	115.544575735664	157.970364768418	136.757470252041	-0.444508945050626	0.160721197310781	-2.76571449496544	0.00567982380522758	0.0233503867548245
-TR3788|c0_g1_i1	wt_GSNO	wt_ph8	128.115824993653	24.010679388938	76.0632521912957	2.41599826196159	0.930388620648254	2.59676248004649	0.00941069736444863	0.0348195802484599
-TR5075|c0_g1_i1	wt_GSNO	wt_ph8	8.81552188359314	126.23137395943	67.5234479215117	-3.83892667969009	1.51640337447055	-2.53159993199728	0.011354345783228	0.0381918903617669
-TR1492|c0_g1_i2	wt_GSNO	wt_ph8	1368.89238848897	813.514514376559	1091.20345143276	0.750717599362045	0.314762309207928	2.38503015577424	0.0170777214032423	0.0526563076599971
-TR1678|c0_g1_i1	wt_GSNO	wt_ph8	0.695005959508731	7.10082184137838	3.89791390044355	-3.29023865439926	1.5074251817588	-2.18268786684349	0.0290588040465388	0.0827058269016874
-TR1479|c0_g1_i1	wt_GSNO	wt_ph8	353.92669362375	305.546165789569	329.736429706659	0.212056310257658	0.102841330599285	2.0619755600394	0.0392100628615421	0.0987833713777749
-TR1859|c3_g1_i1	wt_GSNO	wt_ph8	0	2.05957798928713	1.02978899464357	-3.32897459707672	1.62131131542189	-2.05326057087961	0.0400473127207196	0.0987833713777749
-TR2844|c0_g1_i1	wt_GSNO	wt_ph8	220.566338218013	194.214843050373	207.390590634193	0.186796872895526	0.101161116569868	1.84652838194517	0.0648155222548659	0.149885895214377
-TR2107|c1_g1_i1	wt_GSNO	wt_ph8	7.08292121571621	1.78415791317121	4.43353956444371	1.99039306371489	1.13345482120555	1.75604093473959	0.0790814192380851	0.172118383047597
-TR2672|c0_g1_i1	wt_GSNO	wt_ph8	2.07518941673641	7.44710458698621	4.76114700186131	-1.80710364026684	1.37881760417113	-1.31061834052603	0.189986739707575	0.390528298287793
-TR4859|c0_g1_i1	wt_GSNO	wt_ph8	3.10763825129944	1.1806627783491	2.14415051482427	1.36600125700608	1.2414304168313	1.10034460126467	0.271182006077654	0.528091274993326
-TR3091|c0_g1_i1	wt_GSNO	wt_ph8	312.47018793986	293.531643106953	303.000915523406	0.0884824617062972	0.0884687505769758	1.00015498273946	0.317235511103454	0.572534846407878
-TR4163|c0_g1_i1	wt_GSNO	wt_ph8	221.469120691076	207.118822998308	214.293971844692	0.0967338751775769	0.0982736079923787	0.984332183927538	0.32495221012339	0.572534846407878
-TR1894|c2_g1_i1	wt_GSNO	wt_ph8	2.85762748931802	1.47338219762144	2.16550484346973	0.974874448083219	1.21963227734233	0.799318340612911	0.424105846774723	0.713268924121126
-TR3249|c0_g1_i1	wt_GSNO	wt_ph8	2.06512931203634	4.15451161800812	3.10982046502223	-1.06280923847799	1.42172379433194	-0.747549729923031	0.454731796166148	0.726065302514322
-TR5212|c0_g1_i1	wt_GSNO	wt_ph8	102.736339436612	86.4452993262187	94.5908193814151	0.250307109752951	0.347207101059694	0.720915871216346	0.470961277306587	0.726065302514322
-TR1122|c0_g1_i1	wt_GSNO	wt_ph8	1.29006258579706	0.5946183773076	0.942340481552333	1.01745920560278	1.75106315862361	0.581052259932493	0.56120523253296	1
-TR2011|c5_g1_i1	wt_GSNO	wt_ph8	7.597917075274	4.42090354598533	6.00941031062966	0.776221433822186	1.38068634268934	0.562199689981896	0.573979972628347	0.849490359489954
-TR1837|c2_g1_i1	wt_GSNO	wt_ph8	2.16507864525674	1.46465683073113	1.81486773799393	0.574055870722254	1.31330872914193	0.437106567545105	0.662034064585522	0.882648546299865
-TR1982|c2_g1_i1	wt_GSNO	wt_ph8	5.5352448786851	10.687042573374	8.11114372602957	-0.948745824078601	2.34310116245329	-0.404910312572778	0.685543437736556	0.882648546299865
-TR2182|c3_g2_i6	wt_GSNO	wt_ph8	1.29006258579706	1.76655578876639	1.52830918728173	-0.570835750385155	1.46441538912588	-0.389804528567464	0.69668109483689	0.882648546299865
-TR1449|c0_g1_i1	wt_GSNO	wt_ph8	98.9943307118646	106.843279101242	102.918804906553	-0.106933839690288	0.276431863357554	-0.386836156988073	0.69887750768045	0.882648546299865
-TR4277|c0_g1_i1	wt_GSNO	wt_ph8	153.969096204861	149.159426886469	151.564261545665	0.0465928591854992	0.127909639606222	0.364263861026723	0.715660983486377	0.882648546299865
-TR3854|c0_g1_i1	wt_GSNO	wt_ph8	2260.55060252051	1927.46472630351	2094.00766441201	0.229965172704227	0.793466242289153	0.289823511635197	0.771951259799022	0.910963182508483
-TR127|c1_g1_i1	wt_GSNO	wt_ph8	1.20754470361908	1.49113571265046	1.34934020813477	-0.373671738849606	1.38864714646401	-0.269090488394483	0.787860049737066	0.910963182508483
-TR2090|c0_g1_i1	wt_GSNO	wt_ph8	9.46045896251181	5.6546754787973	7.55756722065455	0.740040477295998	3.75055668025179	0.197314836272869	0.843581169905129	0.945833432923932
-TR3807|c0_g1_i1	wt_GSNO	wt_ph8	0.347502979754365	0.292870809896544	0.320186894825454	0.331202385322154	1.89086385045429	0.175159298350635	0.86095446505486	1
-TR131|c0_g1_i1	wt_GSNO	wt_ph8	1275.67603302799	1312.2934796972	1293.9847563626	-0.0408368749216097	0.405274721880973	-0.100763439506112	0.919738250126613	0.956831887096638
-TR5055|c0_g2_i1	wt_GSNO	wt_ph8	5.17791343714095	5.60171771495863	5.38981557604979	-0.113901914254779	1.2463123048955	-0.0913911495596841	0.927181793948424	0.956831887096638
-TR939|c0_g1_i1	wt_GSNO	wt_ph8	92.2508462008296	94.0990807885678	93.1749634946987	-0.0286723936076206	0.345661698999542	-0.0829492931690373	0.933891858779013	0.956831887096638
-TR2487|c0_g1_i1	wt_GSNO	wt_ph8	875.181494043204	882.631049341941	878.906271692572	-0.0122873741271452	0.226999049805604	-0.0541296280212089	0.956831887096638	0.956831887096638
+TR2779|c0_g1_i1	wt_GSNO	wt_ph8	195.849684476753	966.924129135581	581.386906806167	-2.30255444666643	0.142496869452394	-16.1586318037371	9.87286349231705e-59	3.65295949215731e-57
+TR1891|c0_g1_i1	wt_GSNO	wt_ph8	128.246229498835	343.028289972482	235.637259735659	-1.41742353970608	0.104322254921704	-13.586971838079	4.78470241007372e-42	8.85169945863638e-41
+TR4761|c0_g1_i1	wt_GSNO	wt_ph8	184.029205648389	351.782300021135	267.905752834762	-0.941259207260895	0.0933372308442406	-10.0844989587451	6.4694390401545e-24	7.97897481619054e-23
+TR24|c0_g1_i1	wt_GSNO	wt_ph8	39.3724575919554	183.288101009647	111.330279300801	-2.22846767043702	0.242443002218073	-9.19171784728418	3.86617044826114e-20	3.57620766464156e-19
+TR3638|c0_g1_i1	wt_GSNO	wt_ph8	174.266398355818	297.555274221606	235.910836288712	-0.761689698593791	0.096931480326081	-7.85802193499407	3.90246977316646e-15	2.88782763214318e-14
+TR2122|c0_g2_i2	wt_GSNO	wt_ph8	190.673533226329	328.707071692642	259.690302459485	-0.789061688115737	0.103094089827314	-7.65380139091815	1.95123561209759e-14	1.20326196079352e-13
+TR4669|c0_g2_i1	wt_GSNO	wt_ph8	165.630009730314	0	82.8150048651569	9.98638581786287	2.40591101973569	4.15077105343653	3.31357095210528e-05	0.000175145893182708
+TR2278|c0_g1_i1	wt_GSNO	wt_ph8	426.804298570637	315.99710709695	371.400702833793	0.433055347501054	0.106340324733697	4.07235306630417	4.65405596938926e-05	0.000215250088584253
+TR4084|c0_g1_i1	wt_GSNO	wt_ph8	115.544575735664	157.970364768418	136.757470252041	-0.444508945050625	0.160721197310796	-2.76571449496517	0.00567982380523222	0.0233503867548436
+TR3788|c0_g1_i1	wt_GSNO	wt_ph8	128.115824993653	24.010679388938	76.0632521912957	2.41599826196159	0.930388620648679	2.59676248004531	0.00941069736448111	0.0348195802485801
+TR5075|c0_g1_i1	wt_GSNO	wt_ph8	8.81552188359314	126.23137395943	67.5234479215117	-3.83892667969009	1.51640337447128	-2.53159993199606	0.0113543457832674	0.0381918903618995
+TR1492|c0_g1_i2	wt_GSNO	wt_ph8	1368.89238848897	813.514514376559	1091.20345143276	0.750717599362044	0.314762309207961	2.38503015577399	0.0170777214032538	0.0526563076600326
+TR1678|c0_g1_i1	wt_GSNO	wt_ph8	0.695005959508731	7.10082184137838	3.89791390044355	-3.29023865439928	1.50742518175894	-2.18268786684328	0.0290588040465541	0.0827058269017309
+TR1479|c0_g1_i1	wt_GSNO	wt_ph8	353.92669362375	305.546165789569	329.736429706659	0.212056310257659	0.102841330599274	2.06197556003964	0.0392100628615187	0.0987833713777822
+TR1859|c3_g1_i1	wt_GSNO	wt_ph8	0	2.05957798928713	1.02978899464357	-3.32897459707671	1.62131131542191	-2.05326057087958	0.0400473127207225	0.0987833713777822
+TR2844|c0_g1_i1	wt_GSNO	wt_ph8	220.566338218013	194.214843050373	207.390590634193	0.186796872895529	0.101161116569857	1.8465283819454	0.0648155222548327	0.149885895214301
+TR2107|c1_g1_i1	wt_GSNO	wt_ph8	7.08292121571621	1.78415791317121	4.43353956444371	1.99039306371489	1.13345482120575	1.75604093473928	0.0790814192381375	0.172118383047711
+TR2672|c0_g1_i1	wt_GSNO	wt_ph8	2.07518941673641	7.44710458698621	4.76114700186131	-1.80710364026684	1.3788176041713	-1.31061834052587	0.189986739707629	0.390528298287903
+TR4859|c0_g1_i1	wt_GSNO	wt_ph8	3.10763825129944	1.1806627783491	2.14415051482427	1.36600125700608	1.24143041683139	1.1003446012646	0.271182006077686	0.528091274993389
+TR3091|c0_g1_i1	wt_GSNO	wt_ph8	312.47018793986	293.531643106953	303.000915523406	0.0884824617062953	0.0884687505769775	1.00015498273942	0.317235511103473	0.572534846408031
+TR4163|c0_g1_i1	wt_GSNO	wt_ph8	221.469120691076	207.118822998308	214.293971844692	0.0967338751775785	0.098273607992398	0.984332183927362	0.324952210123477	0.572534846408031
+TR1894|c2_g1_i1	wt_GSNO	wt_ph8	2.85762748931802	1.47338219762144	2.16550484346973	0.974874448083218	1.21963227734242	0.799318340612854	0.424105846774756	0.713268924121181
+TR3249|c0_g1_i1	wt_GSNO	wt_ph8	2.06512931203634	4.15451161800812	3.10982046502223	-1.06280923847798	1.42172379433197	-0.747549729923012	0.454731796166159	0.726065302514524
+TR5212|c0_g1_i1	wt_GSNO	wt_ph8	102.736339436612	86.4452993262187	94.5908193814151	0.250307109752951	0.347207101059796	0.720915871216134	0.470961277306718	0.726065302514524
+TR1122|c0_g1_i1	wt_GSNO	wt_ph8	1.29006258579706	0.5946183773076	0.942340481552333	1.01745920560277	1.75106315862354	0.581052259932512	0.561205232532948	1
+TR2011|c5_g1_i1	wt_GSNO	wt_ph8	7.597917075274	4.42090354598533	6.00941031062966	0.776221433822191	1.38068634268979	0.562199689981717	0.573979972628469	0.849490359490134
+TR1837|c2_g1_i1	wt_GSNO	wt_ph8	2.16507864525674	1.46465683073113	1.81486773799393	0.574055870722253	1.31330872914198	0.437106567545087	0.662034064585536	0.882648546299866
+TR1982|c2_g1_i1	wt_GSNO	wt_ph8	5.5352448786851	10.687042573374	8.11114372602957	-0.9487458240786	2.34310116245464	-0.404910312572544	0.685543437736728	0.882648546299866
+TR2182|c3_g2_i6	wt_GSNO	wt_ph8	1.29006258579706	1.76655578876639	1.52830918728173	-0.570835750385155	1.46441538912588	-0.389804528567465	0.69668109483689	0.882648546299866
+TR1449|c0_g1_i1	wt_GSNO	wt_ph8	98.9943307118646	106.843279101242	102.918804906553	-0.106933839690289	0.276431863357607	-0.386836156987999	0.698877507680504	0.882648546299866
+TR4277|c0_g1_i1	wt_GSNO	wt_ph8	153.969096204861	149.159426886469	151.564261545665	0.0465928591855008	0.127909639606227	0.364263861026722	0.715660983486378	0.882648546299866
+TR3854|c0_g1_i1	wt_GSNO	wt_ph8	2260.55060252051	1927.46472630351	2094.00766441201	0.229965172704227	0.793466242289089	0.289823511635221	0.771951259799004	0.910963182508494
+TR127|c1_g1_i1	wt_GSNO	wt_ph8	1.20754470361908	1.49113571265046	1.34934020813477	-0.373671738849602	1.38864714646406	-0.269090488394471	0.787860049737076	0.910963182508494
+TR2090|c0_g1_i1	wt_GSNO	wt_ph8	9.46045896251181	5.6546754787973	7.55756722065455	0.740040477295999	3.75055668025179	0.19731483627287	0.843581169905129	0.945833432923932
+TR3807|c0_g1_i1	wt_GSNO	wt_ph8	0.347502979754365	0.292870809896544	0.320186894825454	0.331202385322155	1.89086385045428	0.175159298350637	0.860954465054859	1
+TR131|c0_g1_i1	wt_GSNO	wt_ph8	1275.67603302799	1312.2934796972	1293.9847563626	-0.0408368749216137	0.405274721880999	-0.100763439506115	0.91973825012661	0.956831887096637
+TR5055|c0_g2_i1	wt_GSNO	wt_ph8	5.17791343714095	5.60171771495863	5.38981557604979	-0.113901914254778	1.2463123048958	-0.0913911495596612	0.927181793948442	0.956831887096637
+TR939|c0_g1_i1	wt_GSNO	wt_ph8	92.2508462008296	94.0990807885678	93.1749634946987	-0.0286723936076184	0.345661698999674	-0.0829492931689995	0.933891858779043	0.956831887096637
+TR2487|c0_g1_i1	wt_GSNO	wt_ph8	875.181494043204	882.631049341941	878.906271692572	-0.0122873741271473	0.22699904980564	-0.0541296280212096	0.956831887096637	0.956831887096637
Binary file test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.DESeq2.DE_results.MA_n_Volcano.pdf has changed
--- a/test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.edgeR.DE_results	Sun Dec 19 16:21:54 2021 +0000
+++ b/test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.edgeR.DE_results	Tue Apr 11 19:55:15 2023 +0000
@@ -1,40 +1,40 @@
 sampleA	sampleB	logFC	logCPM	PValue	FDR
-TR2779|c0_g1_i1	wt_GSNO	wt_ph8	-2.23948335958727	15.9163308249372	1.20766376889896e-237	4.70988869870595e-236
-TR1492|c0_g1_i2	wt_GSNO	wt_ph8	0.807859120941235	16.8439348559211	2.37986391219743e-61	4.64073462878498e-60
-TR1891|c0_g1_i1	wt_GSNO	wt_ph8	-1.35697452203657	14.6311197032228	1.60645028176433e-35	2.08838536629363e-34
-TR4761|c0_g1_i1	wt_GSNO	wt_ph8	-0.880921757190946	14.8138260614735	1.59143301924913e-24	1.5516471937679e-23
-TR2122|c0_g2_i2	wt_GSNO	wt_ph8	-0.729785350305026	14.7699678361852	6.52776857951534e-13	5.09165949202196e-12
-TR3854|c0_g1_i1	wt_GSNO	wt_ph8	0.289859344737128	17.7786469452325	6.1302236270955e-12	3.98464535761207e-11
-TR3638|c0_g1_i1	wt_GSNO	wt_ph8	-0.702510801497461	14.6355179638282	5.62335492840333e-11	3.133012031539e-10
-TR2278|c0_g1_i1	wt_GSNO	wt_ph8	0.490901034745758	15.2921454021456	1.53296499052609e-09	7.47320432881468e-09
-TR24|c0_g1_i1	wt_GSNO	wt_ph8	-2.16007337608378	13.5636496776551	8.67157466173412e-09	3.75768235341812e-08
-TR5075|c0_g1_i1	wt_GSNO	wt_ph8	-3.7524485458028	12.8683202800317	5.50095216588421e-08	2.14537134469484e-07
-TR4669|c0_g2_i1	wt_GSNO	wt_ph8	10.4044948993067	13.1110475123695	1.35189372056785e-06	4.79307773655872e-06
-TR3788|c0_g1_i1	wt_GSNO	wt_ph8	2.47698512550917	13.0240883091698	1.80487840553907e-05	5.86585481800198e-05
-TR1479|c0_g1_i1	wt_GSNO	wt_ph8	0.272661827455658	15.1172528121102	0.000483095512098729	0.00144928653629619
-TR1678|c0_g1_i1	wt_GSNO	wt_ph8	-3.02812287247775	9.36059212330112	0.0074853976481696	0.0208521791627582
-TR2107|c1_g1_i1	wt_GSNO	wt_ph8	1.98032359155541	9.36544178725855	0.0305238827180189	0.0756824353198294
-TR2844|c0_g1_i1	wt_GSNO	wt_ph8	0.244755727600329	14.4560017424587	0.0310492042337762	0.0756824353198294
-TR1859|c3_g1_i1	wt_GSNO	wt_ph8	-4.12978123132011	8.37588761488442	0.0428877609330621	0.0983895691993777
-TR3091|c0_g1_i1	wt_GSNO	wt_ph8	0.148576217250104	14.9963238698071	0.0547318692708507	0.11858571675351
-TR2672|c0_g1_i1	wt_GSNO	wt_ph8	-1.64029381826409	9.53984158811941	0.100507062957769	0.206303971334369
-TR4163|c0_g1_i1	wt_GSNO	wt_ph8	0.156926020788278	14.5006265631178	0.113620071038851	0.22155913852576
-TR4859|c0_g1_i1	wt_GSNO	wt_ph8	1.3062724221166	8.73091245897321	0.181160758857669	0.3364414093071
-TR4084|c0_g1_i1	wt_GSNO	wt_ph8	-0.390578563212142	13.8603174460746	0.270419882900116	0.479380701504752
-TR1982|c2_g1_i1	wt_GSNO	wt_ph8	-0.866592651710305	10.0958159836705	0.312186869456376	0.515984430920105
-TR1894|c2_g1_i1	wt_GSNO	wt_ph8	0.989932992780787	8.78384403630691	0.317528880566218	0.515984430920105
-TR4277|c0_g1_i1	wt_GSNO	wt_ph8	0.107189584823599	14.0046148411409	0.347278576725125	0.541754579691195
-TR2487|c0_g1_i1	wt_GSNO	wt_ph8	0.0467513454249246	16.526653433485	0.376403968202147	0.560230359736405
-TR3249|c0_g1_i1	wt_GSNO	wt_ph8	-1.00369455926223	9.08504250192555	0.387851787509819	0.560230359736405
-TR5212|c0_g1_i1	wt_GSNO	wt_ph8	0.310409394484433	13.3365591825697	0.416163942507532	0.572783249883747
-TR2011|c5_g1_i1	wt_GSNO	wt_ph8	0.799376994792807	9.70509536731836	0.425915749913555	0.572783249883747
-TR1837|c2_g1_i1	wt_GSNO	wt_ph8	0.59484087321072	8.66193471010726	0.588495494688377	0.76504414309489
-TR2090|c0_g1_i1	wt_GSNO	wt_ph8	0.766971023107968	9.89421471118339	0.638322407555079	0.8030507707951
-TR131|c0_g1_i1	wt_GSNO	wt_ph8	0.0187996511046741	17.0827735361623	0.697507705031756	0.850087515507453
-TR1122|c0_g1_i1	wt_GSNO	wt_ph8	0.908051089281089	8.22928258978683	0.753364106379395	0.890339398448377
-TR1449|c0_g1_i1	wt_GSNO	wt_ph8	-0.0452741219590205	13.4583026590017	0.919111339143084	1
-TR939|c0_g1_i1	wt_GSNO	wt_ph8	0.0309689709592036	13.3146949564453	0.956245904999637	1
-TR5055|c0_g2_i1	wt_GSNO	wt_ph8	-0.0548476287872344	9.62768102188797	0.999999999999985	1
-TR2182|c3_g2_i6	wt_GSNO	wt_ph8	-0.517423422896207	8.5297276065799	1	1
-TR127|c1_g1_i1	wt_GSNO	wt_ph8	-0.299043611515333	8.4576897025083	1	1
-TR3807|c0_g1_i1	wt_GSNO	wt_ph8	0.266132577378544	7.94319410024963	1	1
+TR2779|c0_g1_i1	wt_GSNO	wt_ph8	-2.23950613357817	15.9163032020312	4.60955581344059e-235	1.79772676724183e-233
+TR1492|c0_g1_i2	wt_GSNO	wt_ph8	0.807687320151986	16.8439413499966	1.06317515303199e-90	2.07319154841239e-89
+TR5075|c0_g1_i1	wt_GSNO	wt_ph8	-3.74688019557381	12.8681343619696	5.1381781460234e-32	6.67963158983042e-31
+TR24|c0_g1_i1	wt_GSNO	wt_ph8	-2.16553693339805	13.5635491898429	9.2971773987615e-26	9.06474796379246e-25
+TR3854|c0_g1_i1	wt_GSNO	wt_ph8	0.290142827557204	17.7786481597017	1.25773893145984e-24	9.81036366538678e-24
+TR3788|c0_g1_i1	wt_GSNO	wt_ph8	2.47729608121809	13.0242288909359	1.10830409992816e-22	7.20397664953306e-22
+TR1891|c0_g1_i1	wt_GSNO	wt_ph8	-1.3583596459138	14.6310791041785	1.59601754746587e-15	8.89209776445273e-15
+TR4761|c0_g1_i1	wt_GSNO	wt_ph8	-0.879210949997969	14.8138025433621	1.16981383272981e-13	5.70284243455784e-13
+TR2122|c0_g2_i2	wt_GSNO	wt_ph8	-0.729742458144456	14.7699470890569	4.10258938208877e-06	1.77778873223847e-05
+TR3638|c0_g1_i1	wt_GSNO	wt_ph8	-0.706925054082112	14.6354932126397	1.54507784026086e-05	6.02580357701737e-05
+TR4669|c0_g2_i1	wt_GSNO	wt_ph8	10.4046228735587	13.1113136633968	0.000139728809507287	0.000495402142798563
+TR1678|c0_g1_i1	wt_GSNO	wt_ph8	-3.01399259671531	9.36047067579877	0.000442811746352842	0.00143913817564674
+TR2278|c0_g1_i1	wt_GSNO	wt_ph8	0.489116151456685	15.2921561061716	0.00123564582245084	0.00370693746735251
+TR2107|c1_g1_i1	wt_GSNO	wt_ph8	1.97628703812853	9.36554809158219	0.00657205660686984	0.0183078719762803
+TR1479|c0_g1_i1	wt_GSNO	wt_ph8	0.27208346223967	15.1172591193697	0.0367666005878079	0.0955931615283007
+TR1859|c3_g1_i1	wt_GSNO	wt_ph8	-4.1298851005078	8.3758408307508	0.0437166707415215	0.106559384932459
+TR4084|c0_g1_i1	wt_GSNO	wt_ph8	-0.387761437724876	13.8602939725323	0.0668673830079525	0.153401643371185
+TR2672|c0_g1_i1	wt_GSNO	wt_ph8	-1.63593346878775	9.53972870485612	0.0715566666179246	0.155039444338837
+TR1982|c2_g1_i1	wt_GSNO	wt_ph8	-0.864358765411198	10.0957379798877	0.108379561457656	0.222463310360452
+TR5212|c0_g1_i1	wt_GSNO	wt_ph8	0.312770273727969	13.3365736924153	0.135331780456409	0.263896971889998
+TR2844|c0_g1_i1	wt_GSNO	wt_ph8	0.241817510473408	14.4560087242059	0.15465951473335	0.287224813076222
+TR3091|c0_g1_i1	wt_GSNO	wt_ph8	0.14889261782812	14.9963282436933	0.186547888961471	0.324612319602237
+TR4859|c0_g1_i1	wt_GSNO	wt_ph8	1.30848594262338	8.73097118348756	0.191438034637217	0.324612319602237
+TR2011|c5_g1_i1	wt_GSNO	wt_ph8	0.790825548309762	9.70516893221035	0.218107108399401	0.354424051149027
+TR4163|c0_g1_i1	wt_GSNO	wt_ph8	0.155999611692108	14.5006318412937	0.284866034395977	0.444391013657724
+TR1894|c2_g1_i1	wt_GSNO	wt_ph8	0.986980002958084	8.78386674332455	0.331299000761855	0.496948501142782
+TR3249|c0_g1_i1	wt_GSNO	wt_ph8	-0.985518730250915	9.08501700013798	0.456425031570127	0.65928060115685
+TR4277|c0_g1_i1	wt_GSNO	wt_ph8	0.105816203369183	14.0046181837143	0.523017417566317	0.728488545895941
+TR2487|c0_g1_i1	wt_GSNO	wt_ph8	0.0464385825187709	16.5266539544117	0.56789954734259	0.759378620070234
+TR131|c0_g1_i1	wt_GSNO	wt_ph8	0.0192051247671651	17.0827736541362	0.598052390607106	0.759378620070234
+TR1837|c2_g1_i1	wt_GSNO	wt_ph8	0.590866113458774	8.6619486530175	0.603608646722493	0.759378620070234
+TR2090|c0_g1_i1	wt_GSNO	wt_ph8	0.774122590048598	9.89437120476407	0.740004802646486	0.88514773566839
+TR1122|c0_g1_i1	wt_GSNO	wt_ph8	0.904237754221878	8.22931948652769	0.748971160950176	0.88514773566839
+TR1449|c0_g1_i1	wt_GSNO	wt_ph8	-0.0429337811569824	13.4582943043574	0.870095339425673	0.988074012458205
+TR939|c0_g1_i1	wt_GSNO	wt_ph8	0.0314734152791246	13.3146965055009	0.886733088103517	0.988074012458205
+TR5055|c0_g2_i1	wt_GSNO	wt_ph8	-0.0547681668951162	9.62768076070569	1	1
+TR2182|c3_g2_i6	wt_GSNO	wt_ph8	-0.52401851151559	8.52973766897149	1	1
+TR127|c1_g1_i1	wt_GSNO	wt_ph8	-0.306284780231878	8.45768988187045	1	1
+TR3807|c0_g1_i1	wt_GSNO	wt_ph8	0.273602957097835	7.94319392916032	1	1
Binary file test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.edgeR.DE_results.MA_n_Volcano.pdf has changed
--- a/test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.voom.DE_results	Sun Dec 19 16:21:54 2021 +0000
+++ b/test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.voom.DE_results	Tue Apr 11 19:55:15 2023 +0000
@@ -1,40 +1,40 @@
 sampleA	sampleB	logFC	logCPM	PValue	FDR
-TR2779|c0_g1_i1	wt_GSNO	wt_ph8	-2.23795519272237	15.9076254017254	2.92187316761645e-09	1.13953053537042e-07
-TR1492|c0_g1_i2	wt_GSNO	wt_ph8	0.807554446371668	16.8426446227048	5.58321346448906e-08	1.08872662557537e-06
-TR24|c0_g1_i1	wt_GSNO	wt_ph8	-2.16839334936064	13.5222768601527	3.73856822091501e-07	4.86013868718952e-06
-TR3788|c0_g1_i1	wt_GSNO	wt_ph8	2.47096654484901	13.0144557887788	1.245732049043e-06	9.71670998253539e-06
-TR5075|c0_g1_i1	wt_GSNO	wt_ph8	-3.68481140303272	12.7944067233298	3.44359702134355e-06	2.23833806387331e-05
-TR3854|c0_g1_i1	wt_GSNO	wt_ph8	0.290746293924475	17.7782076349597	5.25322144866517e-07	5.12189091244854e-06
-TR1891|c0_g1_i1	wt_GSNO	wt_ph8	-1.35768165107067	14.6117632515968	5.28666359293828e-06	2.79053243123467e-05
-TR4761|c0_g1_i1	wt_GSNO	wt_ph8	-0.878920056028248	14.8002262876656	5.72416908971214e-06	2.79053243123467e-05
-TR2122|c0_g2_i2	wt_GSNO	wt_ph8	-0.730166040402744	14.7551588447381	0.000213340170514583	0.000924474072229861
-TR3638|c0_g1_i1	wt_GSNO	wt_ph8	-0.708321413581678	14.6195575978943	0.000258928735946659	0.00100982207019197
-TR2107|c1_g1_i1	wt_GSNO	wt_ph8	1.90861736829884	8.90712643491077	0.00457979737107378	0.0148843414559898
-TR1678|c0_g1_i1	wt_GSNO	wt_ph8	-2.86408187112217	8.67828416118206	0.00614682516189	0.01844047548567
-TR2278|c0_g1_i1	wt_GSNO	wt_ph8	0.503051556783977	15.2850549214884	0.00155857674629228	0.00552586300958173
-TR1859|c3_g1_i1	wt_GSNO	wt_ph8	-1.96144637998691	6.77065030795652	0.0428269385052548	0.0982500353944082
-TR2672|c0_g1_i1	wt_GSNO	wt_ph8	-1.69730734417424	8.97832173338033	0.0866262290356731	0.160877282494822
-TR1479|c0_g1_i1	wt_GSNO	wt_ph8	0.277933522953326	15.1098597149167	0.0157877120065803	0.0439800548754737
-TR1982|c2_g1_i1	wt_GSNO	wt_ph8	-0.859948395691952	9.74982883974683	0.0845253825418736	0.160877282494822
-TR4859|c0_g1_i1	wt_GSNO	wt_ph8	1.04376243585308	7.84838377560073	0.178339170085147	0.289801151388364
-TR2011|c5_g1_i1	wt_GSNO	wt_ph8	0.835627288758852	9.33803398810951	0.117576176969539	0.20843049553691
-TR4084|c0_g1_i1	wt_GSNO	wt_ph8	-0.383433512314591	13.8345091917852	0.0320674039619619	0.083375250301101
-TR1894|c2_g1_i1	wt_GSNO	wt_ph8	0.899367664455804	7.86698528437277	0.236693956821629	0.369242572641742
-TR5212|c0_g1_i1	wt_GSNO	wt_ph8	0.317453614519532	13.3093804544918	0.0408068910563242	0.0982500353944082
-TR2182|c3_g2_i6	wt_GSNO	wt_ph8	-0.988859576038597	7.34392475064937	0.332144974966109	0.462630500845651
-TR3249|c0_g1_i1	wt_GSNO	wt_ph8	-1.18548803762213	8.36747688877935	0.296376188714782	0.444564283072173
-TR1837|c2_g1_i1	wt_GSNO	wt_ph8	0.83411458992077	7.6102620160458	0.393260306376011	0.528867308574635
-TR3807|c0_g1_i1	wt_GSNO	wt_ph8	0.40219136988549	5.09566487188118	0.681998347783062	0.765740423023185
-TR4669|c0_g2_i1	wt_GSNO	wt_ph8	6.05037553674292	13.1239272719772	0.480074268471172	0.603964402270185
+TR2779|c0_g1_i1	wt_GSNO	wt_ph8	-2.23795519272236	15.9076254017254	2.92187316761747e-09	1.13953053537081e-07
+TR1492|c0_g1_i2	wt_GSNO	wt_ph8	0.807554446371668	16.8426446227048	5.58321346449028e-08	1.0887266255756e-06
+TR24|c0_g1_i1	wt_GSNO	wt_ph8	-2.16839334936065	13.5222768601527	3.73856822091552e-07	4.86013868719017e-06
+TR3788|c0_g1_i1	wt_GSNO	wt_ph8	2.47096654484901	13.0144557887788	1.24573204904324e-06	9.71670998253725e-06
+TR5075|c0_g1_i1	wt_GSNO	wt_ph8	-3.68481140303272	12.7944067233298	3.44359702134402e-06	2.23833806387361e-05
+TR3854|c0_g1_i1	wt_GSNO	wt_ph8	0.290746293924475	17.7782076349597	5.253221448666e-07	5.12189091244935e-06
+TR1891|c0_g1_i1	wt_GSNO	wt_ph8	-1.35768165107067	14.6117632515968	5.28666359293914e-06	2.79053243123478e-05
+TR4761|c0_g1_i1	wt_GSNO	wt_ph8	-0.87892005602825	14.8002262876656	5.72416908971236e-06	2.79053243123478e-05
+TR2122|c0_g2_i2	wt_GSNO	wt_ph8	-0.73016604040274	14.7551588447381	0.000213340170514584	0.000924474072229863
+TR3638|c0_g1_i1	wt_GSNO	wt_ph8	-0.708321413581678	14.6195575978943	0.000258928735946679	0.00100982207019205
+TR2107|c1_g1_i1	wt_GSNO	wt_ph8	1.90861736829884	8.90712643491077	0.00457979737107358	0.0148843414559891
+TR1678|c0_g1_i1	wt_GSNO	wt_ph8	-2.86408187112217	8.67828416118206	0.00614682516188998	0.01844047548567
+TR2278|c0_g1_i1	wt_GSNO	wt_ph8	0.503051556783975	15.2850549214884	0.00155857674629243	0.00552586300958226
+TR1859|c3_g1_i1	wt_GSNO	wt_ph8	-1.96144637998691	6.77065030795652	0.0428269385052536	0.0982500353944054
+TR2672|c0_g1_i1	wt_GSNO	wt_ph8	-1.69730734417424	8.97832173338033	0.0866262290356742	0.160877282494824
+TR1479|c0_g1_i1	wt_GSNO	wt_ph8	0.277933522953328	15.1098597149167	0.0157877120065796	0.0439800548754716
+TR1982|c2_g1_i1	wt_GSNO	wt_ph8	-0.859948395691952	9.74982883974683	0.0845253825418728	0.160877282494824
+TR4859|c0_g1_i1	wt_GSNO	wt_ph8	1.04376243585308	7.84838377560073	0.178339170085145	0.28980115138836
+TR2011|c5_g1_i1	wt_GSNO	wt_ph8	0.835627288758852	9.33803398810951	0.117576176969538	0.208430495536908
+TR4084|c0_g1_i1	wt_GSNO	wt_ph8	-0.383433512314591	13.8345091917852	0.0320674039619627	0.0833752503011029
+TR1894|c2_g1_i1	wt_GSNO	wt_ph8	0.899367664455804	7.86698528437277	0.236693956821627	0.369242572641738
+TR5212|c0_g1_i1	wt_GSNO	wt_ph8	0.317453614519528	13.3093804544918	0.0408068910563263	0.0982500353944054
+TR2182|c3_g2_i6	wt_GSNO	wt_ph8	-0.988859576038597	7.34392475064937	0.332144974966108	0.46263050084565
+TR3249|c0_g1_i1	wt_GSNO	wt_ph8	-1.18548803762212	8.36747688877935	0.296376188714785	0.444564283072177
+TR1837|c2_g1_i1	wt_GSNO	wt_ph8	0.83411458992077	7.6102620160458	0.39326030637601	0.528867308574635
+TR3807|c0_g1_i1	wt_GSNO	wt_ph8	0.40219136988549	5.09566487188118	0.681998347783058	0.765740423023183
+TR4669|c0_g2_i1	wt_GSNO	wt_ph8	6.05037553674292	13.1239272719772	0.480074268471177	0.603964402270191
 TR1122|c0_g1_i1	wt_GSNO	wt_ph8	0.184244267394782	6.64199260311611	0.869699168726351	0.892585988955992
-TR127|c1_g1_i1	wt_GSNO	wt_ph8	-0.354388761220407	7.15556768591471	0.687202943738756	0.765740423023185
-TR2844|c0_g1_i1	wt_GSNO	wt_ph8	0.251980888130202	14.4425124782726	0.0594765231313145	0.128865800117848
-TR2090|c0_g1_i1	wt_GSNO	wt_ph8	-0.862128177746631	9.64998833298881	0.646749723219784	0.764340581987017
-TR3091|c0_g1_i1	wt_GSNO	wt_ph8	0.148831558112849	14.9878570236746	0.0841354210369957	0.160877282494822
+TR127|c1_g1_i1	wt_GSNO	wt_ph8	-0.354388761220407	7.15556768591471	0.687202943738754	0.765740423023183
+TR2844|c0_g1_i1	wt_GSNO	wt_ph8	0.251980888130197	14.4425124782726	0.0594765231313182	0.128865800117856
+TR2090|c0_g1_i1	wt_GSNO	wt_ph8	-0.862128177746631	9.64998833298881	0.646749723219787	0.764340581987021
+TR3091|c0_g1_i1	wt_GSNO	wt_ph8	0.148831558112851	14.9878570236746	0.0841354210369898	0.160877282494824
 TR5055|c0_g2_i1	wt_GSNO	wt_ph8	0.0583511298028353	9.18288041060754	0.918331019801174	0.918331019801174
-TR4163|c0_g1_i1	wt_GSNO	wt_ph8	0.161834057105857	14.4879250602579	0.126768900432688	0.214955961603254
-TR4277|c0_g1_i1	wt_GSNO	wt_ph8	0.103273026252208	13.9874746529507	0.30829078508145	0.445308911784317
-TR939|c0_g1_i1	wt_GSNO	wt_ph8	0.0333503331526365	13.2856573711711	0.715260879184748	0.774865952450143
-TR1449|c0_g1_i1	wt_GSNO	wt_ph8	-0.049884213852527	13.4293306544833	0.75234222467997	0.793009371959969
-TR2487|c0_g1_i1	wt_GSNO	wt_ph8	0.0480185034754555	16.5239765307922	0.407818984620182	0.530164680006236
-TR131|c0_g1_i1	wt_GSNO	wt_ph8	0.0203187870937255	17.0810493411762	0.539920494505425	0.658028102678487
+TR4163|c0_g1_i1	wt_GSNO	wt_ph8	0.161834057105863	14.4879250602579	0.126768900432678	0.214955961603237
+TR4277|c0_g1_i1	wt_GSNO	wt_ph8	0.103273026252208	13.9874746529507	0.308290785081446	0.445308911784311
+TR939|c0_g1_i1	wt_GSNO	wt_ph8	0.0333503331526316	13.2856573711711	0.71526087918478	0.774865952450178
+TR1449|c0_g1_i1	wt_GSNO	wt_ph8	-0.049884213852527	13.4293306544833	0.752342224679971	0.793009371959969
+TR2487|c0_g1_i1	wt_GSNO	wt_ph8	0.0480185034754555	16.5239765307922	0.407818984620183	0.530164680006237
+TR131|c0_g1_i1	wt_GSNO	wt_ph8	0.0203187870937285	17.0810493411762	0.539920494505375	0.658028102678426
Binary file test-data/count/exp_diff/input.matrix.wt_GSNO_vs_wt_ph8.voom.DE_results.MA_n_Volcano.pdf has changed
Binary file test-data/count/qcheck/input.matrix.CPM.log2.prcomp.principal_components.pdf has changed
Binary file test-data/count/qcheck/input.matrix.CPM.log2.sample_cor_matrix.pdf has changed
Binary file test-data/count/qcheck/wt_37.rep_compare.pdf has changed
Binary file test-data/count/qcheck/wt_GSNO.rep_compare.pdf has changed
Binary file test-data/count/qcheck/wt_ph8.rep_compare.pdf has changed
--- a/test-data/filtered/Trinity_filtered_exp.fasta	Sun Dec 19 16:21:54 2021 +0000
+++ b/test-data/filtered/Trinity_filtered_exp.fasta	Tue Apr 11 19:55:15 2023 +0000
@@ -1,4 +1,4 @@
->TRINITY_DN1_c0_g1_i1 len=380 path=[358:0-379] [-1, 358, -2] top_iso:0 pct_iso_expr=NA pct_dom_iso_expr=NA
+>TRINITY_DN1_c0_g1_i1 len=380 path=[358:0-379] [-1, 358, -2] top_iso:0 pct_iso_expr=NA pct_dom_iso_expr=NA max_expr_any=222.00
 CCAAGGTAGAAAACATCCCTGCTGACAAGACCTACCTGTGACATACTCACTCTCTTAGGG
 CTTTTAAAGACAAGCCATTAAAATAGATGACCTTTCACAGACTGAAACTTGAATCACTGC
 AAAATGAATCTAGGTTGCTGTCACTTTTTCTTTTGGGTGGCGGGGCTTGATGTAGATTTT
@@ -6,12 +6,12 @@
 GGAGGTTAGATTTACTGGAAATGTATTCATACTGTGAACTGTGCTCTGATGGTTAGAATG
 AAAAGCTTATCAAGCATTCCATATAACAGTGGATGTAGAAAATGTTTTCAGGTGGATATG
 TATATGGTACAGATGTAAAG
->TRINITY_DN0_c0_g1_i1 len=229 path=[207:0-228] [-1, 207, -2] top_iso:0 pct_iso_expr=NA pct_dom_iso_expr=NA
+>TRINITY_DN0_c0_g1_i1 len=229 path=[207:0-228] [-1, 207, -2] top_iso:0 pct_iso_expr=NA pct_dom_iso_expr=NA max_expr_any=1094.00
 AAATATCACAACCACCTGAACAGGAACTTGGGATAAACAGGCAATGATGAGAGCCGATGT
 TTTTCTGTTGGTGTTTACATTGCTCTGCTCTGTGAAAGGATCCTGCAGCAGAGGCTTCCT
 ACCTGAAAAATGTTTCTCTCAATTGTAGTGTGTGAGTTACTGGTAAGACGCTTACACCTA
 TAACTCAAGGTCGGAATAGTCCCTCCAGTCCCTTTAGTAACCCAGTGGC
->TRINITY_DN2_c1_g1_i1 len=541 path=[519:0-540] [-1, 519, -2] top_iso:0 pct_iso_expr=NA pct_dom_iso_expr=NA
+>TRINITY_DN2_c1_g1_i1 len=541 path=[519:0-540] [-1, 519, -2] top_iso:0 pct_iso_expr=NA pct_dom_iso_expr=NA max_expr_any=65.00
 GTCTGAATTCGCATGTAATGCAGCTTTCCCAGACACAAGTATGGAAGCAATCCGACTTAT
 TCGCCATTGTGCAAAATATGTGTCTGATAGACCGCAGGCTTTCAAGGAGTACACAAGTGA
 TGACATGAGCGTGGCACCTGAAGACAGGGTGTGGGTGAGAGGGTGGTTCCCGATCCTCTT
@@ -22,12 +22,12 @@
 CCAGTATTTAGAAGTTCTCAGCGATGTACTTTTGGATGATATTTTTGCCCAGCTTTACTG
 GTGTGTACAACAAGACAATGAGCAGTTAGCACGATCTGGTACAAACTGCTTAGAAAACGT
 G
->TRINITY_DN2_c3_g1_i1 len=202 path=[180:0-201] [-1, 180, -2] top_iso:0 pct_iso_expr=NA pct_dom_iso_expr=NA
+>TRINITY_DN2_c3_g1_i1 len=202 path=[180:0-201] [-1, 180, -2] top_iso:0 pct_iso_expr=NA pct_dom_iso_expr=NA max_expr_any=425.00
 GGTGAAAAGTTTACTCTTGAAATCTGGGATAAAACGTGTAACTGCACCCTGGATATCTTC
 AAAACCACAATTCCTCACGCGCTTCTGACTTGGCGTCCCACCTCTGGCGAGGCCGAACCC
 CCATCTCCATCAGCTGTGAGTGAAAAGCCGTTGGATGCAATATCACAAAAATCTGTAGAC
 ATACATGATTCTATTCAACCAA
->TRINITY_DN3_c0_g1_i1 len=216 path=[194:0-215] [-1, 194, -2] top_iso:0 pct_iso_expr=NA pct_dom_iso_expr=NA
+>TRINITY_DN3_c0_g1_i1 len=216 path=[194:0-215] [-1, 194, -2] top_iso:0 pct_iso_expr=NA pct_dom_iso_expr=NA max_expr_any=36.00
 ATTGATTTATTTAATAAGAAACCAAAGAGAGGAATACAATACCTCCAAGAACAAGGGATG
 CTTGGCACCACACCCGAAGATATAGCTCAGTTCTTACATCAAGAAGAAAGATTAGACTCT
 ACTCAGGTGGGTGAGTTCCTGGGAGATAATGATAAATTCAATAAAGAAGTCATGTATGCA
--- a/test-data/filtered/Trinity_filtered_hi_iso.fasta	Sun Dec 19 16:21:54 2021 +0000
+++ b/test-data/filtered/Trinity_filtered_hi_iso.fasta	Tue Apr 11 19:55:15 2023 +0000
@@ -1,4 +1,4 @@
->TRINITY_DN1_c0_g1_i1 len=380 path=[358:0-379] [-1, 358, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100
+>TRINITY_DN1_c0_g1_i1 len=380 path=[358:0-379] [-1, 358, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100 max_expr_any=
 CCAAGGTAGAAAACATCCCTGCTGACAAGACCTACCTGTGACATACTCACTCTCTTAGGG
 CTTTTAAAGACAAGCCATTAAAATAGATGACCTTTCACAGACTGAAACTTGAATCACTGC
 AAAATGAATCTAGGTTGCTGTCACTTTTTCTTTTGGGTGGCGGGGCTTGATGTAGATTTT
@@ -6,18 +6,18 @@
 GGAGGTTAGATTTACTGGAAATGTATTCATACTGTGAACTGTGCTCTGATGGTTAGAATG
 AAAAGCTTATCAAGCATTCCATATAACAGTGGATGTAGAAAATGTTTTCAGGTGGATATG
 TATATGGTACAGATGTAAAG
->TRINITY_DN0_c0_g1_i1 len=229 path=[207:0-228] [-1, 207, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100
+>TRINITY_DN0_c0_g1_i1 len=229 path=[207:0-228] [-1, 207, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100 max_expr_any=
 AAATATCACAACCACCTGAACAGGAACTTGGGATAAACAGGCAATGATGAGAGCCGATGT
 TTTTCTGTTGGTGTTTACATTGCTCTGCTCTGTGAAAGGATCCTGCAGCAGAGGCTTCCT
 ACCTGAAAAATGTTTCTCTCAATTGTAGTGTGTGAGTTACTGGTAAGACGCTTACACCTA
 TAACTCAAGGTCGGAATAGTCCCTCCAGTCCCTTTAGTAACCCAGTGGC
->TRINITY_DN2_c0_g1_i1 len=279 path=[257:0-278] [-1, 257, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100
+>TRINITY_DN2_c0_g1_i1 len=279 path=[257:0-278] [-1, 257, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100 max_expr_any=
 TCCAGACCATCGACAACATTGTCTTCTTCCCAGCCACAAGCAAGAAGGAGGATGCAGAGA
 ACTTAGCTGCAGCCCAGAGAGATGCAGTAGACTTCGATGTTCGAGTTGATACTCAAGACC
 AAGGAATGTACCGCTTTTTAACATCACAACAACTGTTCAAGCTACTGGACTGCTTATTAG
 AGTCGCATAGATTTGCAAAAGCATTTAATTCCAACAATGAACAGAGGACTGCTCTGTGGA
 AAGCAGGCTTCAAAGGCAAGTCCAAGCCCAATCTTCTAA
->TRINITY_DN2_c1_g1_i1 len=541 path=[519:0-540] [-1, 519, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100
+>TRINITY_DN2_c1_g1_i1 len=541 path=[519:0-540] [-1, 519, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100 max_expr_any=
 GTCTGAATTCGCATGTAATGCAGCTTTCCCAGACACAAGTATGGAAGCAATCCGACTTAT
 TCGCCATTGTGCAAAATATGTGTCTGATAGACCGCAGGCTTTCAAGGAGTACACAAGTGA
 TGACATGAGCGTGGCACCTGAAGACAGGGTGTGGGTGAGAGGGTGGTTCCCGATCCTCTT
@@ -28,17 +28,17 @@
 CCAGTATTTAGAAGTTCTCAGCGATGTACTTTTGGATGATATTTTTGCCCAGCTTTACTG
 GTGTGTACAACAAGACAATGAGCAGTTAGCACGATCTGGTACAAACTGCTTAGAAAACGT
 G
->TRINITY_DN2_c2_g1_i1 len=240 path=[218:0-239] [-1, 218, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100
+>TRINITY_DN2_c2_g1_i1 len=240 path=[218:0-239] [-1, 218, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100 max_expr_any=
 ACAAGCAGCCTGGCGTGTGGGCTGCGCATTCTCTTCCGGATGTACATGGACGAGAGCAGA
 GTCAGTGCCTGGGAAGAAGTCCAGCAGAGGCTTTTAAACGTCTGCAGGGAAGCGCTGAGC
 TACTTCCTCACTCTAACATCCGAAAGTCACCGGGAAGCCTGGACTAACTTACTGTTACTG
 TTCCTCACTAAAGTTCTGAAGATCAGTGACAGCAGGTTTAAAGCTCACGCATCATTCTAC
->TRINITY_DN2_c3_g1_i1 len=202 path=[180:0-201] [-1, 180, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100
+>TRINITY_DN2_c3_g1_i1 len=202 path=[180:0-201] [-1, 180, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100 max_expr_any=
 GGTGAAAAGTTTACTCTTGAAATCTGGGATAAAACGTGTAACTGCACCCTGGATATCTTC
 AAAACCACAATTCCTCACGCGCTTCTGACTTGGCGTCCCACCTCTGGCGAGGCCGAACCC
 CCATCTCCATCAGCTGTGAGTGAAAAGCCGTTGGATGCAATATCACAAAAATCTGTAGAC
 ATACATGATTCTATTCAACCAA
->TRINITY_DN3_c0_g1_i1 len=216 path=[194:0-215] [-1, 194, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100
+>TRINITY_DN3_c0_g1_i1 len=216 path=[194:0-215] [-1, 194, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100 max_expr_any=
 ATTGATTTATTTAATAAGAAACCAAAGAGAGGAATACAATACCTCCAAGAACAAGGGATG
 CTTGGCACCACACCCGAAGATATAGCTCAGTTCTTACATCAAGAAGAAAGATTAGACTCT
 ACTCAGGTGGGTGAGTTCCTGGGAGATAATGATAAATTCAATAAAGAAGTCATGTATGCA
--- a/test-data/filtered/Trinity_filtered_pct_iso.fasta	Sun Dec 19 16:21:54 2021 +0000
+++ b/test-data/filtered/Trinity_filtered_pct_iso.fasta	Tue Apr 11 19:55:15 2023 +0000
@@ -1,4 +1,4 @@
->TRINITY_DN1_c0_g1_i1 len=380 path=[358:0-379] [-1, 358, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100
+>TRINITY_DN1_c0_g1_i1 len=380 path=[358:0-379] [-1, 358, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100 max_expr_any=222.00
 CCAAGGTAGAAAACATCCCTGCTGACAAGACCTACCTGTGACATACTCACTCTCTTAGGG
 CTTTTAAAGACAAGCCATTAAAATAGATGACCTTTCACAGACTGAAACTTGAATCACTGC
 AAAATGAATCTAGGTTGCTGTCACTTTTTCTTTTGGGTGGCGGGGCTTGATGTAGATTTT
@@ -6,18 +6,18 @@
 GGAGGTTAGATTTACTGGAAATGTATTCATACTGTGAACTGTGCTCTGATGGTTAGAATG
 AAAAGCTTATCAAGCATTCCATATAACAGTGGATGTAGAAAATGTTTTCAGGTGGATATG
 TATATGGTACAGATGTAAAG
->TRINITY_DN0_c0_g1_i1 len=229 path=[207:0-228] [-1, 207, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100
+>TRINITY_DN0_c0_g1_i1 len=229 path=[207:0-228] [-1, 207, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100 max_expr_any=1094.00
 AAATATCACAACCACCTGAACAGGAACTTGGGATAAACAGGCAATGATGAGAGCCGATGT
 TTTTCTGTTGGTGTTTACATTGCTCTGCTCTGTGAAAGGATCCTGCAGCAGAGGCTTCCT
 ACCTGAAAAATGTTTCTCTCAATTGTAGTGTGTGAGTTACTGGTAAGACGCTTACACCTA
 TAACTCAAGGTCGGAATAGTCCCTCCAGTCCCTTTAGTAACCCAGTGGC
->TRINITY_DN2_c0_g1_i1 len=279 path=[257:0-278] [-1, 257, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100
+>TRINITY_DN2_c0_g1_i1 len=279 path=[257:0-278] [-1, 257, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100 max_expr_any=23.00
 TCCAGACCATCGACAACATTGTCTTCTTCCCAGCCACAAGCAAGAAGGAGGATGCAGAGA
 ACTTAGCTGCAGCCCAGAGAGATGCAGTAGACTTCGATGTTCGAGTTGATACTCAAGACC
 AAGGAATGTACCGCTTTTTAACATCACAACAACTGTTCAAGCTACTGGACTGCTTATTAG
 AGTCGCATAGATTTGCAAAAGCATTTAATTCCAACAATGAACAGAGGACTGCTCTGTGGA
 AAGCAGGCTTCAAAGGCAAGTCCAAGCCCAATCTTCTAA
->TRINITY_DN2_c1_g1_i1 len=541 path=[519:0-540] [-1, 519, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100
+>TRINITY_DN2_c1_g1_i1 len=541 path=[519:0-540] [-1, 519, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100 max_expr_any=65.00
 GTCTGAATTCGCATGTAATGCAGCTTTCCCAGACACAAGTATGGAAGCAATCCGACTTAT
 TCGCCATTGTGCAAAATATGTGTCTGATAGACCGCAGGCTTTCAAGGAGTACACAAGTGA
 TGACATGAGCGTGGCACCTGAAGACAGGGTGTGGGTGAGAGGGTGGTTCCCGATCCTCTT
@@ -28,17 +28,17 @@
 CCAGTATTTAGAAGTTCTCAGCGATGTACTTTTGGATGATATTTTTGCCCAGCTTTACTG
 GTGTGTACAACAAGACAATGAGCAGTTAGCACGATCTGGTACAAACTGCTTAGAAAACGT
 G
->TRINITY_DN2_c2_g1_i1 len=240 path=[218:0-239] [-1, 218, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100
+>TRINITY_DN2_c2_g1_i1 len=240 path=[218:0-239] [-1, 218, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100 max_expr_any=11.00
 ACAAGCAGCCTGGCGTGTGGGCTGCGCATTCTCTTCCGGATGTACATGGACGAGAGCAGA
 GTCAGTGCCTGGGAAGAAGTCCAGCAGAGGCTTTTAAACGTCTGCAGGGAAGCGCTGAGC
 TACTTCCTCACTCTAACATCCGAAAGTCACCGGGAAGCCTGGACTAACTTACTGTTACTG
 TTCCTCACTAAAGTTCTGAAGATCAGTGACAGCAGGTTTAAAGCTCACGCATCATTCTAC
->TRINITY_DN2_c3_g1_i1 len=202 path=[180:0-201] [-1, 180, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100
+>TRINITY_DN2_c3_g1_i1 len=202 path=[180:0-201] [-1, 180, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100 max_expr_any=425.00
 GGTGAAAAGTTTACTCTTGAAATCTGGGATAAAACGTGTAACTGCACCCTGGATATCTTC
 AAAACCACAATTCCTCACGCGCTTCTGACTTGGCGTCCCACCTCTGGCGAGGCCGAACCC
 CCATCTCCATCAGCTGTGAGTGAAAAGCCGTTGGATGCAATATCACAAAAATCTGTAGAC
 ATACATGATTCTATTCAACCAA
->TRINITY_DN3_c0_g1_i1 len=216 path=[194:0-215] [-1, 194, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100
+>TRINITY_DN3_c0_g1_i1 len=216 path=[194:0-215] [-1, 194, -2] top_iso:1 pct_iso_expr=100 pct_dom_iso_expr=100 max_expr_any=36.00
 ATTGATTTATTTAATAAGAAACCAAAGAGAGGAATACAATACCTCCAAGAACAAGGGATG
 CTTGGCACCACACCCGAAGATATAGCTCAGTTCTTACATCAAGAAGAAAGATTAGACTCT
 ACTCAGGTGGGTGAGTTCCTGGGAGATAATGATAAATTCAATAAAGAAGTCATGTATGCA