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view PsiCLASS-1.0.2/samtools-0.1.19/bam_lpileup.c @ 0:903fc43d6227 draft default tip
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author | lsong10 |
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date | Fri, 26 Mar 2021 16:52:45 +0000 |
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#include <stdlib.h> #include <stdio.h> #include <assert.h> #include "bam.h" #include "ksort.h" #define TV_GAP 2 typedef struct __freenode_t { uint32_t level:28, cnt:4; struct __freenode_t *next; } freenode_t, *freenode_p; #define freenode_lt(a,b) ((a)->cnt < (b)->cnt || ((a)->cnt == (b)->cnt && (a)->level < (b)->level)) KSORT_INIT(node, freenode_p, freenode_lt) /* Memory pool, similar to the one in bam_pileup.c */ typedef struct { int cnt, n, max; freenode_t **buf; } mempool_t; static mempool_t *mp_init() { return (mempool_t*)calloc(1, sizeof(mempool_t)); } static void mp_destroy(mempool_t *mp) { int k; for (k = 0; k < mp->n; ++k) free(mp->buf[k]); free(mp->buf); free(mp); } static inline freenode_t *mp_alloc(mempool_t *mp) { ++mp->cnt; if (mp->n == 0) return (freenode_t*)calloc(1, sizeof(freenode_t)); else return mp->buf[--mp->n]; } static inline void mp_free(mempool_t *mp, freenode_t *p) { --mp->cnt; p->next = 0; p->cnt = TV_GAP; if (mp->n == mp->max) { mp->max = mp->max? mp->max<<1 : 256; mp->buf = (freenode_t**)realloc(mp->buf, sizeof(freenode_t*) * mp->max); } mp->buf[mp->n++] = p; } /* core part */ struct __bam_lplbuf_t { int max, n_cur, n_pre; int max_level, *cur_level, *pre_level; mempool_t *mp; freenode_t **aux, *head, *tail; int n_nodes, m_aux; bam_pileup_f func; void *user_data; bam_plbuf_t *plbuf; }; void bam_lplbuf_reset(bam_lplbuf_t *buf) { freenode_t *p, *q; bam_plbuf_reset(buf->plbuf); for (p = buf->head; p->next;) { q = p->next; mp_free(buf->mp, p); p = q; } buf->head = buf->tail; buf->max_level = 0; buf->n_cur = buf->n_pre = 0; buf->n_nodes = 0; } static int tview_func(uint32_t tid, uint32_t pos, int n, const bam_pileup1_t *pl, void *data) { bam_lplbuf_t *tv = (bam_lplbuf_t*)data; freenode_t *p; int i, l, max_level; // allocate memory if necessary if (tv->max < n) { // enlarge tv->max = n; kroundup32(tv->max); tv->cur_level = (int*)realloc(tv->cur_level, sizeof(int) * tv->max); tv->pre_level = (int*)realloc(tv->pre_level, sizeof(int) * tv->max); } tv->n_cur = n; // update cnt for (p = tv->head; p->next; p = p->next) if (p->cnt > 0) --p->cnt; // calculate cur_level[] max_level = 0; for (i = l = 0; i < n; ++i) { const bam_pileup1_t *p = pl + i; if (p->is_head) { if (tv->head->next && tv->head->cnt == 0) { // then take a free slot freenode_t *p = tv->head->next; tv->cur_level[i] = tv->head->level; mp_free(tv->mp, tv->head); tv->head = p; --tv->n_nodes; } else tv->cur_level[i] = ++tv->max_level; } else { tv->cur_level[i] = tv->pre_level[l++]; if (p->is_tail) { // then return a free slot tv->tail->level = tv->cur_level[i]; tv->tail->next = mp_alloc(tv->mp); tv->tail = tv->tail->next; ++tv->n_nodes; } } if (tv->cur_level[i] > max_level) max_level = tv->cur_level[i]; ((bam_pileup1_t*)p)->level = tv->cur_level[i]; } assert(l == tv->n_pre); tv->func(tid, pos, n, pl, tv->user_data); // sort the linked list if (tv->n_nodes) { freenode_t *q; if (tv->n_nodes + 1 > tv->m_aux) { // enlarge tv->m_aux = tv->n_nodes + 1; kroundup32(tv->m_aux); tv->aux = (freenode_t**)realloc(tv->aux, sizeof(void*) * tv->m_aux); } for (p = tv->head, i = l = 0; p->next;) { if (p->level > max_level) { // then discard this entry q = p->next; mp_free(tv->mp, p); p = q; } else { tv->aux[i++] = p; p = p->next; } } tv->aux[i] = tv->tail; // add a proper tail for the loop below tv->n_nodes = i; if (tv->n_nodes) { ks_introsort(node, tv->n_nodes, tv->aux); for (i = 0; i < tv->n_nodes; ++i) tv->aux[i]->next = tv->aux[i+1]; tv->head = tv->aux[0]; } else tv->head = tv->tail; } // clean up tv->max_level = max_level; memcpy(tv->pre_level, tv->cur_level, tv->n_cur * 4); // squeeze out terminated levels for (i = l = 0; i < n; ++i) { const bam_pileup1_t *p = pl + i; if (!p->is_tail) tv->pre_level[l++] = tv->pre_level[i]; } tv->n_pre = l; /* fprintf(stderr, "%d\t", pos+1); for (i = 0; i < n; ++i) { const bam_pileup1_t *p = pl + i; if (p->is_head) fprintf(stderr, "^"); if (p->is_tail) fprintf(stderr, "$"); fprintf(stderr, "%d,", p->level); } fprintf(stderr, "\n"); */ return 0; } bam_lplbuf_t *bam_lplbuf_init(bam_pileup_f func, void *data) { bam_lplbuf_t *tv; tv = (bam_lplbuf_t*)calloc(1, sizeof(bam_lplbuf_t)); tv->mp = mp_init(); tv->head = tv->tail = mp_alloc(tv->mp); tv->func = func; tv->user_data = data; tv->plbuf = bam_plbuf_init(tview_func, tv); return (bam_lplbuf_t*)tv; } void bam_lplbuf_destroy(bam_lplbuf_t *tv) { freenode_t *p, *q; free(tv->cur_level); free(tv->pre_level); bam_plbuf_destroy(tv->plbuf); free(tv->aux); for (p = tv->head; p->next;) { q = p->next; mp_free(tv->mp, p); p = q; } mp_free(tv->mp, p); assert(tv->mp->cnt == 0); mp_destroy(tv->mp); free(tv); } int bam_lplbuf_push(const bam1_t *b, bam_lplbuf_t *tv) { return bam_plbuf_push(b, tv->plbuf); }