<?xml version="1.0" encoding="UTF-8"?>
<tool id="met4j_ScopeNetwork" name="ScopeNetwork" version="1.1.0">
  <description>Perform a network expansion from a set of compound seeds to create a scope network</description>
  <xrefs>
    <xref type="bio.tools">met4j</xref>
  </xrefs>
  <requirements>
    <container type="singularity">oras://registry.forgemia.inra.fr/metexplore/met4j/met4j-singularity:1.1.0</container>
  </requirements>
  <command detect_errors="exit_code"><![CDATA[sh /usr/bin/met4j.sh networkAnalysis.ScopeNetwork -i "$sbmlFilePath"
 -s "$seedsFilePath"
#if str($sideCompoundFile) != 'None':
 -sc "$sideCompoundFile"
#end if
 $includeSides
#if str($reactionToIgnoreFile) != 'None':
 -ir "$reactionToIgnoreFile"
#end if
 $trace
 -o "$output"
]]></command>
  <inputs>
    <param argument="-i" format="sbml" label="input SBML file: path to network used for computing scope, in sbml format." name="sbmlFilePath" optional="false" type="data" value=""/>
    <param argument="-s" format="" label="input seeds file: tabulated file containing node of interest ids" name="seedsFilePath" optional="false" type="data" value=""/>
    <param argument="-sc" format="" label="an optional file containing list of ubiquitous side compounds to be considered available by default but ignored during expansion" name="sideCompoundFile" optional="true" type="data" value=""/>
    <param argument="-ssc" checked="false" falsevalue="" label="show side compounds in output network" name="includeSides" truevalue="-ssc" type="boolean" value="false"/>
    <param argument="-ir" format="" label="an optional file containing list of reaction to ignore (forbid inclusion in scope" name="reactionToIgnoreFile" optional="true" type="data" value=""/>
    <param argument="-t" checked="false" falsevalue="" label="trace inclusion step index for each node in output" name="trace" truevalue="-t" type="boolean" value="false"/>
  </inputs>
  <outputs>
    <data format="gml" name="output"/>
  </outputs>
  <tests>
    <test>
      <param name="sbmlFilePath" value="toy_model.xml"/>
      <param name="seedsFilePath" value="seeds.txt"/>
      <param name="sideCompoundFile" value="sides.txt"/>
      <output ftype="gml" name="output">
        <assert_contents>
          <has_line_matching expression=".*node.*" n="9"/>
          <has_line_matching expression=".*edge.*" n="11"/>
        </assert_contents>
      </output>
    </test>
  </tests>
  <help><![CDATA[Perform a network expansion from a set of compound seeds to create a scope network
The scope of a set of compounds (seed) refer to the maximal metabolic network that can be extended from them,where the extension process consist of adding a reaction to the network if and only if all of its substrates are either a seed or a product of a previously added reaction
For more information, see Handorf, Ebenhöh and Heinrich (2005). *Expanding metabolic networks: scopes of compounds, robustness, and evolution.* Journal of molecular evolution, 61(4), 498-512. (https://doi.org/10.1007/s00239-005-0027-1)]]></help>
  <citations/>
</tool>