Mercurial > repos > miller-lab > genome_diversity
annotate nucleotide_diversity_pi.py @ 22:95a05c1ef5d5
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author | Richard Burhans <burhans@bx.psu.edu> |
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date | Mon, 11 Mar 2013 11:28:06 -0400 |
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children | 8997f2ca8c7a |
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1 #!/usr/bin/env python |
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2 |
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3 import sys |
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4 import subprocess |
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5 from Population import Population |
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6 |
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7 ################################################################################ |
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8 |
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9 def run_program(prog, args, stdout_file=None, space_to_tab=False): |
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10 #print "args: ", ' '.join(args) |
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11 p = subprocess.Popen(args, bufsize=-1, executable=prog, stdin=None, stdout=subprocess.PIPE, stderr=subprocess.PIPE) |
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12 (stdoutdata, stderrdata) = p.communicate() |
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13 rc = p.returncode |
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14 |
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15 if stdout_file is not None: |
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16 with open(stdout_file, 'w') as ofh: |
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17 lines = stdoutdata.split('\n') |
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18 for line in lines: |
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19 line = line.strip() |
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20 if line: |
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21 if space_to_tab: |
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22 line = line.replace(' ', '\t') |
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23 print >> ofh, line |
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24 |
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25 if rc != 0: |
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26 print >> sys.stderr, "FAILED: rc={0}: {1}".format(rc, ' '.join(args)) |
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27 print >> sys.stderr, stderrdata |
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28 sys.exit(1) |
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29 |
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30 ################################################################################ |
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31 |
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32 if len(sys.argv) < 8: |
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33 print >> sys.stderr, "Usage" |
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34 sys.exit(1) |
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35 |
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36 gd_saps_file, gd_snps_file, covered_intervals_file, gd_indivs_file, output_file = sys.argv[1:6] |
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37 individual_metadata = sys.argv[6:] |
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38 |
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39 p_total = Population() |
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40 p_total.from_tag_list(individual_metadata) |
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41 |
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42 p1 = Population() |
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43 p1.from_population_file(gd_indivs_file) |
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44 if not p_total.is_superset(p1): |
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45 print >> sys.stderr, 'There is an individual in the population individuals that is not in the SNP table' |
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46 sys.exit(1) |
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47 |
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48 ################################################################################ |
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49 |
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50 prog = 'get_pi' |
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51 |
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52 args = [ prog ] |
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53 args.append(gd_saps_file) |
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54 args.append(gd_snps_file) |
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55 args.append(covered_intervals_file) |
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56 |
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57 columns = p1.column_list() |
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58 for column in columns: |
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59 args.append('{0}'.format(column)) |
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60 |
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61 run_program(None, args, stdout_file=output_file) |
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62 |
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63 sys.exit(0) |
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64 |