Mercurial > repos > yufei-luo > s_mart
diff SMART/Java/Python/structure/Mapping.py @ 6:769e306b7933
Change the repository level.
author | yufei-luo |
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date | Fri, 18 Jan 2013 04:54:14 -0500 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/SMART/Java/Python/structure/Mapping.py Fri Jan 18 04:54:14 2013 -0500 @@ -0,0 +1,255 @@ +# +# Copyright INRA-URGI 2009-2010 +# +# This software is governed by the CeCILL license under French law and +# abiding by the rules of distribution of free software. You can use, +# modify and/ or redistribute the software under the terms of the CeCILL +# license as circulated by CEA, CNRS and INRIA at the following URL +# "http://www.cecill.info". +# +# As a counterpart to the access to the source code and rights to copy, +# modify and redistribute granted by the license, users are provided only +# with a limited warranty and the software's author, the holder of the +# economic rights, and the successive licensors have only limited +# liability. +# +# In this respect, the user's attention is drawn to the risks associated +# with loading, using, modifying and/or developing or reproducing the +# software by the user in light of its specific status of free software, +# that may mean that it is complicated to manipulate, and that also +# therefore means that it is reserved for developers and experienced +# professionals having in-depth computer knowledge. Users are therefore +# encouraged to load and test the software's suitability as regards their +# requirements in conditions enabling the security of their systems and/or +# data to be ensured and, more generally, to use and operate it in the +# same conditions as regards security. +# +# The fact that you are presently reading this means that you have had +# knowledge of the CeCILL license and that you accept its terms. +# +from SMART.Java.Python.structure.SubMapping import SubMapping +from SMART.Java.Python.structure.Transcript import Transcript +from SMART.Java.Python.structure.Interval import Interval + +class Mapping(object): + """A class that represents a mapping""" + + def __init__(self): + self.targetInterval = None + self.queryInterval = None + self.subMappings = [] + self.size = None + self.transcript = None + self.tags = {} + + + def copy(self, mapping): + for subMapping in mapping.subMappings: + newSubMapping = SubMapping(subMapping) + self.addSubMapping(newSubMapping) + self.targetInterval = Interval(mapping.targetInterval) + self.queryInterval = Interval(mapping.queryInterval) + self.size = mapping.size + self.tags = {} + for tag in mapping.tags: + self.tags[tag] = mapping[tag] + self.transcript.copy(mapping.transcript) + + + def setTargetInterval(self, interval): + self.targetInterval = Interval(interval) + if self.queryInterval != None: + self.setDirection(self.targetInterval.getDirection() * self.queryInterval.getDirection()) + + + def setQueryInterval(self, interval): + self.queryInterval = Interval(interval) + if self.targetInterval != None: + self.setDirection(self.targetInterval.getDirection() * self.queryInterval.getDirection()) + + + def getQueryInterval(self): + return self.queryInterval + + + def addSubMapping(self, subMapping): + subMappingCopy = SubMapping(subMapping) + self.subMappings.append(subMappingCopy) + + if self.targetInterval: + self.targetInterval.setStart(min(self.targetInterval.getStart(), subMapping.targetInterval.getStart())) + self.targetInterval.setEnd(max(self.targetInterval.getEnd(), subMapping.targetInterval.getEnd())) + else: + self.setTargetInterval(subMapping.targetInterval) + if self.queryInterval: + self.queryInterval.setStart(min(self.queryInterval.getStart(), subMapping.queryInterval.getStart())) + self.queryInterval.setEnd(max(self.queryInterval.getEnd(), subMapping.queryInterval.getEnd())) + else: + self.setQueryInterval(subMapping.queryInterval) + + if self.getDirection() != 0: + subMapping.setDirection(self.getDirection()) + if self.size == None: + self.size = 0 + if "identity" in subMapping.getTagNames() and "identity" not in self.getTagNames(): + self.setTagValue("identity", subMapping.getTagValue("identity")) + elif "identity" in subMapping.getTagNames() and subMapping.size != None: + self.setTagValue("identity", (self.getTagValue("identity") * self.size + subMapping.getTagValue("identity") * subMapping.size) / (self.size + subMapping.size)) + if subMapping.size != None: + self.size += subMapping.size + if "nbMismatches" in subMapping.getTagNames() and "nbMismatches" not in self.getTagNames(): + self.setTagValue("nbMismatches", subMapping.getTagValue("nbMismatches")) + elif "nbMismatches" in subMapping.getTagNames(): + self.setTagValue("nbMismatches", self.getTagValue("nbMismatches") + subMapping.getTagValue("nbMismatches")) + if "nbGaps" in subMapping.getTagNames() and "nbGaps" not in self.getTagNames(): + self.setTagValue("nbGaps", subMapping.getTagValue("nbGaps")) + elif "nbGaps" in subMapping.getTagNames(): + self.setTagValue("nbGaps", self.getTagValue("nbGaps") + subMapping.getTagValue("nbGaps")) + + + def setDirection(self, direction): + for subMapping in self.subMappings: + subMapping.setDirection(direction) + + + def getDirection(self): + if not self.subMappings: + raise Exception("Error! Mapping '%s' has no submapping" % (self)) + return self.subMappings[0].getDirection() + + + def setSize(self, size): + self.size = size + if "identity" in self.getTagNames(): + self.setTagValue("nbMismatches", self.size - round(self.size * self.getTagValue("identity") / 100.0)) + + + def setTagValue(self, name, value): + self.tags[name] = value + self.transcript = None + + + def getTagValue(self, name): + return self.tags[name] + + + def getTagNames(self): + return self.tags.keys() + + + def setIdentity(self, identity): + self.setTagValue("identity", identity) + if self.size != None and "nbMismatches" not in self.getTagNames(): + nbMismatches = 0 if self.size == 0 else self.size - round(self.size * self.getTagValue("identity") / 100.0) + self.setTagValue("nbMismatches", nbMismatches) + + + def setNbOccurrences(self, nbOccurrences): + self.setTagValue("nbOccurrences", nbOccurrences) + + + def setNbMismatches(self, nbMismatches): + self.setTagValue("nbMismatches", nbMismatches) + if self.size != None and "identity" not in self.getTagNames(): + identity = 100 if self.size == 0 else (self.size - self.getTagValue("nbMismatches")) / float(self.size) * 100 + self.setTagValue("identity", identity) + + + def setNbGaps(self, nbGaps): + self.setTagValue("nbGaps", nbGaps) + + + def setRank(self, rank): + self.setTagValue("rank", rank) + + + def setEvalue(self, evalue): + self.setTagValue("evalue", evalue) + + + def setOccurrence(self, occurrence): + self.setTagValue("occurrence", occurrence) + + + def setBestRegion(self, bestRegion): + self.setTagValue("bestRegion", bestRegion) + + + def mergeExons(self, distance): + previousSubMapping = None + subMappings = [] + for subMapping in self.subMappings: + if previousSubMapping == None: + subMappings.append(subMapping) + previousSubMapping = subMapping + else: + targetDistance = subMapping.targetInterval.getDistance(previousSubMapping.targetInterval) + queryDistance = subMapping.queryInterval.getDistance(previousSubMapping.queryInterval) + if targetDistance <= distance: + self.setTagValue("nbGaps", self.getTagValue("nbGaps") + queryDistance) + previousSubMapping.merge(subMapping) + else: + subMappings.append(subMapping) + previousSubMapping = subMapping + self.subMappings = subMappings + + + def getTranscript(self): + """ + Extract a transcript from this mapping + @return: a transcript + """ + if self.transcript != None: + return self.transcript + self.transcript = Transcript() + self.transcript.copy(self.targetInterval) + self.transcript.setDirection(self.getDirection()) + self.transcript.setName(self.queryInterval.getName()) + self.transcript.removeExons() + if len(self.subMappings) > 1: + for subMapping in self.subMappings: + self.transcript.addExon(subMapping.targetInterval) + cpt = 1 + for exon in self.transcript.exons: + exon.setDirection(self.transcript.getDirection()) + exon.setName("%s-exon%d" % (self.transcript.getName(), cpt)) + exon.setChromosome(self.transcript.getChromosome()) + cpt += 1 + self.transcript.setDirection(self.getDirection()) + self.transcript.sortExons() + for tag in self.tags: + if "bestRegion" not in self.getTagNames(): + self.transcript.setTagValue("bestRegion", "(self)") + self.transcript.setTagValue(tag, self.getTagValue(tag)) + return self.transcript + + + def getChromosome(self): + if not self.subMappings: + raise Exception("Error! Mapping '%s' has no submapping" % (self)) + return self.subMappings[0].targetInterval.getChromosome() + + + + def getErrorScore(self): + return self.getTagValue("nbGaps") * 3 + self.getTagValue("nbMismatches") + (len(self.subMappings) - 1) * 0.1 + + + def printGBrowseReference(self): + return self.getTranscript().printGBrowseReference() + + + def printGBrowseLine(self): + return self.getTranscript().printGBrowseLine() + + + def printGBrowse(self): + return self.getTranscript().printGBrowse() + + + def printBed(self): + return self.getTranscript().printBed() + + + def __str__(self): + return "%s ---- %s" % (str(self.getTranscript()), ", ". join([str(submapping) for submapping in self.subMappings]))