Mercurial > repos > rnateam > mafft
changeset 18:0a507f4bd19a draft default tip
planemo upload for repository https://github.com/bgruening/galaxytools/tree/master/tools/mafft commit 3216eed8c66b2fff7c571ab27d3f1e6aaddc186f
| author | bgruening |
|---|---|
| date | Mon, 14 Jul 2025 18:16:36 +0000 |
| parents | 1233363389c1 |
| children | |
| files | macros.xml mafft.xml test-data/mafft_seed_out.aln test-data/seed.aln test-data/seed2.aln |
| diffstat | 5 files changed, 1822 insertions(+), 1 deletions(-) [+] |
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--- a/macros.xml Wed Mar 05 16:46:36 2025 +0000 +++ b/macros.xml Mon Jul 14 18:16:36 2025 +0000 @@ -1,6 +1,6 @@ <macros> <token name="@TOOL_VERSION@">7.526</token> - <token name="@VERSION_SUFFIX@">1</token> + <token name="@VERSION_SUFFIX@">2</token> <token name="@PROFILE@">22.01</token> <!-- currently, the fasta3 executable is named according to its major version => needs updating together with the package requirement! -->
--- a/mafft.xml Wed Mar 05 16:46:36 2025 +0000 +++ b/mafft.xml Mon Jul 14 18:16:36 2025 +0000 @@ -105,6 +105,12 @@ #end if #end if + #if $seed + #for $s in $seed: + --seed '$s' + #end for + #end if + ## handle scoring matrix $datatype_selection.datatype $anysymbol @@ -218,6 +224,7 @@ <expand macro="misc_scoring_scheme" /> </when> </conditional> + <param argument="--seed" type="data" format="fasta" optional="true" multiple="true" label="Use a seed alignment?" help="The --seed option can be used for adding unaligned sequences into a highly reliable alignment (seed) consisting of a small number of sequences. In this option, the aligned letters in the seed alignment are preserved but gaps are not necessarily preserved. If the given alignment (including the gap pattern) has to be completely preserved, use mafft-add."/> <param argument="--anysymbol" type="boolean" truevalue="--anysymbol" falsevalue="" checked="False" label="Support unusual characters?" help="e.g., U as selenocysteine in protein sequence; i as inosine in nucleotide sequence" /> <conditional name="flavour"> <param name="type" type="select" label="MAFFT flavour" help="Run mafft with pre-defined input parameters. Specification of these parameters can be found in the help section. With 'Auto', the tool automatically selects an appropriate strategy from L-INS-i, FFT-NS-i and FFT-NS-2, according to data size from few to many respectively. Default setting: FFT-NS-2."> @@ -487,6 +494,20 @@ <metadata name="sequences" value="39"/> </output> </test> + <!-- test with seed alignments --> + <test expect_num_outputs="1"> + <conditional name="input"> + <param name="mapping" value="implicit"/> + <repeat name="batches"> + <param name="inputs" value="sample_amino.fa"/> + </repeat> + </conditional> + <conditional name="flavour"> + <param name="type" value="mafft-linsi"/> + </conditional> + <param name="seed" value="seed.aln,seed2.aln"/> + <output name="outputAlignment" ftype="fasta" file="mafft_seed_out.aln"/> + </test> </tests> <help><![CDATA[ **What it does**
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/mafft_seed_out.aln Mon Jul 14 18:16:36 2025 +0000 @@ -0,0 +1,1368 @@ +>_seed_PINI_ARATH/9-617 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------HVMTAMVPLYVAMILA- +YGSVKWWKIFTPDQCSGINRFVALFA-----------VPLLSFHFIAANNPYA------- +---MNLRFLAADSLQKVIVLSLLFLWCKLSR---NGSLDWTITLFSLSTLPNTLVMGIPL +LKGMYGN----------------------------------FSGDLMVQIVVLQCIIWYT +LML------------------FLFEYRGAKLLISEQFP-DTAGSIVSIHVDSDIMSLDGR +Q-PLETEAEIKEDGKLHVTVRRSNASRSDIYS-----RRSQGL-SATPRPSNLTNAEIYS +LQSSRNPTPRGSSFNHTDFY---------------SMMASGGGRNSNFGPGEA------- +--------VFGSKGPTPRPSNYEEDGGPAKPTAAGTAAGAGRFHYQSGGSGGGGGAHYPA +PNPGMFSPNTGGGGGTAAKGNAPVVGGKRQDGN------GRDLHMFVWSSSASPVSDVFG +GGGGNHHADYSTATNDHQKDVKISVPQGNSNDNQYVEREEFSFGNKDDDSKVLATDGGNN +ISNKTTQAKVMPPTSVMTRLILIMVWRKLIRNPNSYSSLFGITWSLI-SFKWNIEMP--- +---ALIAKSISILSDAGLGMAMFSL--------GL------------------------- +---FMALNPRIIACGNRRAAFA--------AAMRFVVGPAVMLVASYAVGLRGV--LLHV +AIIQ------------AALPQGIVPFVFAKEYNVHPDILSTAVI---------------- +-FG-MLI-A-LPITL--------------------------------------------- +-------------------------------------------------------LYY +>_seed_Q9FVF6_POPPZ/9-609 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------HVMTAMVPLYVAMILA- +YGSVKWWKIFTPDQCSGINRFVALFA-----------VPLLSFHFISTNDPYN------- +---MNLRFITADSLQKVIVLVVLALWTKLSK---RGCLEWTITLFSLSTLPNTLVMGIPL +LKGMYGD----------------------------------YSGSLMVQVVVLQCIIWYT +LML------------------FMFEYRGAKLLISEQFP-DTAGSIVSIHVDSDIMSLDGR +Q-PLETEAAIKEDGKLHVTVRKSNASRSDIFS-----RRSQGLSSTTPRPSNLTNAEIYS +LQSSRNPTPRGSSFNHTDFY---------------SMMA--AGRNSNFGASDVY------ +-------GLSASRGPTPRPSNFEEEHGGSNKPRFHHYHAPGGATHYPAPNPGMFSPTTAA +SKGVSANANNAAAAAAKKPNGQAQQKAED-------------GRDLHMFVWSSSASPVSD +VFGGHDYGAHDLKDVRVAVSPGKVEGQRENQEDYNLERDDFSFGNRGLDRERNSHEGEKG +GFD--GKPKAMPPTSVMTRLILIMVWRKLIRNPNTYSSLIGLIWSLV-SFRWNVKMP--- +---LIIAKSISILSDAGLGMAMFSL--------GL------------------------- +---FMALQPRIIACGNSIATFS--------MAVRFLTGPAIMAAASIAVGIRGT--LLHI +AIVQ------------AALPQGIVPFVFAKEYNVHPEILSTGVI---------------- +-FG-MLI-A-LPITL--------------------------------------------- +-------------------------------------------------------VYY +>_seed_B8AIF2_ORYSI/9-590 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------HVMTAMVPLYVAMILA- +YGSVKWWRIFTPDQCSGINRFVALFA-----------VPLLSFHFISTNNPYT------- +---MNLRFIAADTLQKLMVLAMLTAWSHLSR---RGSLEWTITLFSLSTLPNTLVMGIPL +LKGMYGE----------------------------------FSGSLMVQIVVLQCIIWYT +LML------------------FMFEYRGARMLITEQFP-DTAANIASIVVDPDVVSLDGR +RDAIETETEVKEDGRIHVTVRRSNASRSDIYS-----RRSMGFSSTTPRPSNLTNAEIYS +LQSSRNPTPRGSSFNHTDFY---------------SMV----GRSSNFGAADA------- +--------FGVRTGATPRPSNYEDDASKPKYPLPASNAAPMAGHYPAPNPAVSSAPKGAK +KAATNGQAKGEDLHMFVWSS-------------------------------SASPVSDVF +GGGAPDYNDAAAVKSPRKMDGAKDREDYVERDDFSFGNRGVMDRDAEAGDEKAAAAAGAD +PSKAMAAPTAMPPTSVMTRLILIMVWRKLIRNPNTYSSLIGLIWSLV-CFRWNFEMP--- +---AIVLKSISILSDAGLGMAMFSL--------GL------------------------- +---FMALQPHIIACGNKVATYA--------MAVRFLAGPAVMAAASFAVGLRGT--LLHV +AIVQ------------AALPQGIVPFVFAKEYSVHPSILSTAVI---------------- +-FG-MLI-A-LPITL--------------------------------------------- +-------------------------------------------------------VYY +>_seed_PIN6_ARATH/9-565 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------TVMCAMAPLYFAMFVA- +YGSVKWCKIFTPAQCSGINRFVSVFA-----------VPVLSFHFISQNNPYK------- +---MDTMFILADTLSKIFVFVLLSLWAVFFK---AGGLDWLITLFSIATLPNTLVMGIPL +LQAMYGD----------------------------------YTQTLMVQLVVLQCIIWYT +LLL------------------FLFELRAARLLIRAEFPGQAAGSIAKIQVDDDVISLDGM +D-PLRTETETDVNGRIRLRIRRSVSSVPDSVMSSSLC--------LTPRASNLSNAEIFS +VN----------TPNNRFFHGGGGSGTLQFYNGSNEIMF-CNGDLGGFGFTRPGLGASPR +RLSGYASSDAYSLQPTPRASNFNELDVNGNGTPVWMKSPAAGRIYRQSSPKMMWESGQRH +AAK--------------------------------------------------------- +---------DINGSVPEKEISFRDALKAAPQATAAGGGASMEEGAAGKDTTPVA-AIG-K +-QE-------MPSAIVMMRLILTVVGRKLSRNPNTYSSLLGLVWSLI-SFKWNIPMP--- +---NIVDFSIKIISDAGLGMAMFSL--------GL------------------------- +---FMALQPKMIPCGAKKATMG--------MLIRFISGPLFMAGASLLVGLRGS--RLHA +AIVQ------------AALPQGIVPFVFAREYNLHPDLLSTLVI---------------- +-FG-MIV-S-LPVTI--------------------------------------------- +-------------------------------------------------------LYY +>_seed_YFDV_ECOLI/4-307 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------FFIGDLLPIIVIMLLG- +YFSGRR-ETFSEDQARAFNKLVLNYA-----------LPAALFVSITRANREM------- +---IFADTRLTLVSLVVIVGCFFFSWFGCYK-FFKRTHAEAAVCALIAGSPTIGFLGFAV +LDPIYGD----------------------SV---------STGLVVAIISIIVNAITIPI +GLY------------------LLNPSSGADGKK--------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +-------------------NSNLSALISAAKEPVVWAPVLATILVLV-GVKIP------- +---AAWDPTFNLIAKANSGVAVFAA--------GL------------------------- +---TLAAHKFEFSAEIAYN-----------TFLKLILMPLALLLVGMACHLNSE--HLQM +MVLA------------GALPPAFSGIIIASRFNVYTRTGTASLA---------------- +-VS-VLG-F-VVTAP--------------------------------------------- +-------------------------------------------------------LWI +>_seed_YWKB_BACSU/5-315 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------DILILLAPIFFVIVLG- +WFAGHF-GSYDAKSAKGVSTLVTKYA-----------LPAHFIAGILTTSRSE------- +---FLSQVPLMISLIIGIVGFYIIILLVCRF-IFKYDLTNSSVFSLNSAQPTFAFMGIPV +LGSLFGA----------------------------------NEVAIPIAVTGIVVNAILD +PLA------------------IIIATVGESSKKNEESGD--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------SFWKMTGKSILHGLCEPLAAAPLISMILVLVFNFTLP------- +---ELGVKMLDQLGSTTSGVALFAV--------GV------------------------- +---TVGIRKIKLSMPAIG-----------IALLKVAVQPALMFLIALAIGLPAD-QTTKA +ILL-------------VAFPGSAVAAMIATRFEKQEEETATAFV---------------- +-VS-AIL-S-LISLP--------------------------------------------- +-------------------------------------------------------III +>_seed_P71425_KLEPN/4-313 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------VIIHALAPIFVIMLLG- +FWAGKA-GMVDNKNVSLLNIFVMDFA-----------LPATLFSATVQTPWAG------- +---IVAQSPLVLVLTGAMWITYAAIYFLATS-VFKRTPQDGAVLTLTVALPNYAALGLPI +LGSVLGE---------------------------------GASTSLSVAVSIACGSVLMT +PFC------------------LLILEREKARAAGENSG---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------STLAMLPVLMWRSVKKPIVWGPLLGVVLSAI-GIKMP------- +---DLLLASIKPLGLAATAAALFLT--------GV------------------------- +---ILSARKLQLNALIAAS-----------TIVKLLVQPFIAWGLVMLLGLHGS-IAITA +ILM-------------IALAAGFFGVVFGNRFGVQSPDAEAVLL---------------- +-LS-SVL-C-ILSLP--------------------------------------------- +-------------------------------------------------------LFI +>_seed_Q98L58_RHILO/3-308 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------PLTETVLFVFSLVALG- +YLAGLT-GYLRPASGEGISDFAVSVA-----------MPLLLFQTMVKADFHG------- +-----VAPWPLWGAYFTAVAITWAAGHLVTTRIFGRDARAGVVGGVSSAYSNVVLLGAPF +ILGIFGP-----------------------S---------GFEVLSLLVSVHLPVMMMAS +IVL------------------FEMFGRGGGEHV--------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------HPLRVLRSFLRRLFINPLIIGILLGLAWRLS-GVPLP------- +---SLVMRLVDALANTAGPVALFAM--------GL------------------------- +---SLRRFGVSGNVRPALA----------LSALKLFLMPALVLAFVLLLGLPPL--TAKV +AVVV------------AALPSGINSYLIAVQFNTGQALASNQMT---------------- +-IA-TAC-A-AVTTA--------------------------------------------- +-------------------------------------------------------FWL +>_seed_O67397_AQUAE/2-289 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------FIYEKVFFILLIIAFA- +YTLKRG-GIFKEEHALPFINYVIYFA-----------LPFTIFKNLRF---LE------- +---IGKEVLGVVLIAWGAIFLSILFAFLFGK-FLKLEEKTLRAFLLVSSFGNTAFMGYPF +LYALEGN----------------------------------EGLKYAILYDQLGSFLMVI +TLG--------------------------------------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------LFLAIGKFDLKELILFPPFIALVLSFLLHGV-RFP--------- +---QFFEHSVEIISGSLIPVILFSL--------GL------------------------- +---RLNFTDMKSDYRTLFSA----------LFIKMFLVPLLILVFLKIFGLTSL--PYRV +ALIE------------SAMPPMVFAGVLALKYELDFRLAFSAIT---------------- +-LG-IVI-S-LFTVP--------------------------------------------- +-------------------------------------------------------VFR +>_seed_Q97M34_CLOAB/2-296 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------YVFEQIVILFLIMGIG- +YYAAKS-KIIDDDTTSHLSNFIVSIT-----------LPLMILTSFNVEYSRK------- +---TVITIINLLVFSVAAFIISIVIGKII---SFKFAMDKRDILMFMSIFSNCGFIGFPV +LKVVYGN----------------------------------KGVLYTSIFNLVYNVFIWT +IGI------------------VIINDKREKIDY--------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +--------------------------KKILFNHNIIAVIVGVFLMLL-SIKIP------- +---YVMSSAFNLIGSMTAPLSMIVI--------GS------------------------- +---ILA--------GVDFNDIFKDWSLYYIAILRLIIIPLIIYFALKPFQINKI--VIGV +IIIC------------EAMPGGTLCPILAKSCNRNFKYASKIVL---------------- +-IT-TIL-S-MMTIP--------------------------------------------- +-------------------------------------------------------FMT +>_seed_YB8B_YEAST/13-413 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------LVFESVLQVVIIALAG- +FWSASS-GLLPKQSQKIISLLNVDLF-----------TPCLIFSKLAKSLSMA------- +---KIFEIAIIPIFFGLTTGISFISGKIMSR-ILDLDKDETNFVVANSVFGNSNSLPVSL +TLSLAYTLPNLTW-D-----QIPNDNRDNVA---------SRGILYLLIFQQIGQMLRWS +WGY------------------NKLMKWSGENTQHMPPSQVQSLLERTPNIDNEELVNEEQ +EEQELLEEENNRMNSSFLSSSSIGDKIWQKSCTVFER----------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +--------------------------IRANLNPPLYSMIFAVVVAAI-GPLQRELFMEDG +FINNTFAEAVTQLGSVSIPLILVVL--------GS------------------------- +---NLYPSA-----EVFPKTVHHSKLLIGSIIGRMILPSCFLLPIIAIAV------KYIN +VSILDDPIFLVVGFLLTVSPPAIQLTQITQLNEFFEAEMADILF---------------- +-WG-YAV-L-SLPVS--------------------------------------------- +-------------------------------------------------------IIV +>_seed_YDQ4_SCHPO/18-440 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------PIIESDLEVIVIALGG- +YVLAKK-GFLPRDAQKVISSLNVYFF-----------TPCLVFEKVGNGLNLK------- +---MLIDLSLLPVFYVIISAASILISFLLAK-LFRLTPRQRNFATACITFQNSNSLPLAL +VSSLATTVKDLLW-D-----KIPDDTPDKVA---------SRGIMYLLIFSQLGQALRWS +YGY------------------RILLSPNQPEDPLPIGNRSWSHSDVNEEEIQNLLASSAN +VDGVQNSVQANEGSTVQTDSSAISKNDNVQVETSNEEVGGFGAASSKISK---------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------------FIVLLLDFFSPPLYSLFIALFIAVV-PPLQRFFFEEGS +FVEGSITSGIRMAGQVAVPMILVVL--------GA------------------------- +---SLATDISKTEPTQEVRKNNDTRVIIVCLLGRMVVVPLALLPAFSLLS------YFSE +ISTVDDPVFVVVIFLLVGSPTAIQLTQICQLNGVFERECAKVLW---------------- +-WS-YAV-F-TPPNS--------------------------------------------- +-------------------------------------------------------LLL +>_seed_PILS4_ARATH/9-407 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------ASSKPVVETLLITSVGF +YLALDTVNLLGHDARKHLNNIVFYVF-----------SPSLIGSRLADSVTYE------- +---SLVKMWFMPVNVLLTFMIGSLLGWIVIV-ITKPPSQLRGLIISCCASGNLGTMPLII +IPAICKE-------K-----GGPFGDSESCE---------KYGMGYVTLSMT--AFFISV +YKHDTNWYVSGGNGLLMDLYINLMR------VLSNSPVETHTHSIESNYDDSCKVQLISS +K------------------------------------------EEEKEEDNHQVGRWEEV +KQ---------------------------------------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------RVVSLSKKVNLGSIFAPATIAAIIALVIGLI-TPLRNLIIGTVA +PF-RVIQDSLTLLGDGAIPAMTLIL--------GG------------------------- +---NLLKGMRRSEVRSSEMKNSCIIGV---LVARYILLPVSGVLLVRGAY-------KLD +LVTS-EPLYQFVLLLQYAVPPAMNLGTKTQLFGAGESECSVIML---------------- +-WT-YSL-A-AVSLT--------------------------------------------- +-------------------------------------------------------VWP +>_seed_PILS5_ARATH/9-388 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------VASMPVIQVLFMSLVGA +FMASDRCKLFPVEARNSMNKVVFVLF-----------APALMFANLAQTVTLE------- +---DIISWWFMPVNMGLTFLIGGLLGWLVVK-ILKPPPYLEGLIVATCSAGNMGNLPIIL +VPAICDE-------D-----KSPFGNRSVCR---------TVGLSYASFSMALGGFYIWT +YTF------------------RLIKGSAMKVQAIEESEKIAIKSSNSDLEADHKTHLLGA +P-----------------------------------------EDKENKVVKEKTGFWRKG +VD---------------------------------------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------FLHEI-----LEELLAPPTLGAIIGFIFGAV-RWLRNLIIGDDA +PL-RIVQSTAKLLGDGTIPCMTIIL--------GG------------------------- +---NLIQG-----LRSSAVKPMVVLGI---VCVRYIAMPIIGIGIVLTAA-------NLG +FLPA-DPLFQYVLMLQFTLPPAMNIGTMTQLYNVAQDECSVLML---------------- +-WT-YLV-A-ILALT--------------------------------------------- +-------------------------------------------------------VWS +>_seed_PILS2_ARATH/18-441 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------SGVVPLLKLICLTVIGL +LLAHPKTQLVPRATFRLLSKLVFALF-----------LPCLIFTELGESITLD------- +---NIVQWWFIPVNVLLSAVVGSLIGYLVVL-ICRPPPEFNRFTIVMTAFGNTGNLLLAI +VSSVCHT--------------KTNPFGPNCN---------SRGVSYVSFAQWVAVILVYT +VVY------------------HMMEPPLEYYEVVEEEG-VEIEEINVENHDASRPLLVEA +EWPGIEDKETEHCKTPFIARVFNSISSFSQTSFPEVDLGGEYGGESSSPRSIQCLAEPRV +MR---------------------------------------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------RIRVVAEQTPVKHILQPPTIASLLAIIIGSV-PQLKSVVFGYDA +PL-SFITDSLNIMGSAMVPSVMLVL--------GG------------------------- +---MLSEGPNESTLGLRTTIGI--------SVARLLVLPLVGIGIVMSAD-------KLG +LISSADPMFKFVLLLQYSTPSAILLGAIASLRGYAVREASALLF---------------- +-WQ-HIF-A-LLSLT--------------------------------------------- +-------------------------------------------------------FYI +>_seed_PILS6_ARATH/30-423 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------IAVMPIAKVFTMCFLGL +LMASKYVNILPPSGRKLLNGLVFSLL-----------LPCLIFSQLGQAVTLQ------- +---KMLQWWFIPVNVVLGTISGSIIGFIVAS-IVRPPYPYFKFTIIQIGVGNIGNVPLVL +LAALCRD-------T-----SNPFGDSEKCS---------IDGTAYISFGQWVGAIILYT +YVY------------------QMFAPPPEGFDAEEENLALKTLPVDAAPEQVPLLTQNFP +KDFSPTQDL--------------------------------LPVQSTEPRGRGVSRKGKI +AQ---------------------------------------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------IFVFLYEKLKLKQIVQPAIVASILAMILGAI-PFTKKLIFTNGA +PL-FFFTDSCMILGDAMIPCILLAL--------GG------------------------- +---NLINGPGSSKLGFKTTAAI--------IIGRLVLVPPVGLGIVTVAD-------KLG +FLPADDKMFRFVLLLQHTMPTSVLSGAVANLRGCG-RESAAVLF---------------- +-WV-HIF-A-IFSMA--------------------------------------------- +-------------------------------------------------------GWM +>_seed_PIN4_ARATH/9-611 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------TVLTAVVPLYVAMILA- +YGSVQWWKIFSPDQCSGINRFVAIFA-----------VPLLSFHFISTNDPYA------- +---MNFRFVAADTLQKIIMLVLLALWANLTK---NGSLEWMITIFSLSTLPNTLVMGIPL +LIAMYGT----------------------------------YAGSLMVQVVVLQCIIWYT +LLL------------------FLFEYRGAKLLIMEQFP-ETGASIVSFKVESDVVSLDGH +D-FLETDAEIGNDGKLHVTVRKSNASRRSLMM--------------TPRPSNLTGAEIYS +LS----STPRGSNFNHSDFY---------------SVMGFPGGRLSNFGPADLY------ +-------SVQSSRGPTPRPSNFEENNAVKYGFYNNTNSSVPAAGSYPAPNPEFSTGTGVS +TKPNKIPKENQQQLQEKDSKASHDAKELHMFVWSSSASPVSDVFGGGAGDNVATEQSEQG +AKEIRMVVSDQPRKSNARGGGDDIGGLDSGEGEREIEKATAGLNKMGSNSTAELEAAG-G +-DGGGNNGTHMPPTSVMTRLILIMVWRKLIRNPNTYSSLIGLIWALV-AYRWHVAMP--- +---KILQQSISILSDAGLGMAMFSL--------GL------------------------- +---FMALQPKIIACGNSVATFA--------MAVRFITGPAIMAVAGIAIGLHGD--LLRI +AIVQ------------AALPQGIVPFVFAKEYNVHPTILSTGVI---------------- +-FG-MLI-A-LPITL--------------------------------------------- +-------------------------------------------------------VYY +>_seed_PIN7_ARATH/9-614 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------TVLTAVIPLYVAMILA- +YGSVRWWKIFSPDQCSGINRFVAIFA-----------VPLLSFHFISSNNPYA------- +---MNLRFIAADTLQKLIMLTLLIIWANFTR---SGSLEWSITIFSLSTLPNTLVMGIPL +LIAMYGE----------------------------------YSGSLMVQIVVLQCIIWYT +LLL------------------FLFEYRGAKILIMEQFP-ETGASIVSFKVESDVVSLDGH +D-FLETDAQIGDDGKLHVTVRKSNASRRSFYG--------GGGTNMTPRPSNLTGAEIYS +L----NTTPRGSNFNHSDFY---------------SMMGFPGGRLSNFGPADMY------ +-------SVQSSRGPTPRPSNFEESCAMASSPRFGYYPGGAPGSYPAPNPEFSTGNKTGS +KAPKENHHHVGKSNSNDAKELHMFVWGSNGSPV-----SDRAGLQVDNGANEQVGKSDQG +GAKEIRMLISDHTQNGENKAGPMNGDYGGEEESERVKEVPNGLHKLRCNSTAELNPKEAI +ETGETVPVKHMPPASVMTRLILIMVWRKLIRNPNTYSSLIGLIWALV-AFRWDVAMP--- +---KIIQQSISILSDAGLGMAMFSL--------GL------------------------- +---FMALQPKLIACGNSTATFA--------MAVRFFTGPAVMAVAAMAIGLRGD--LLRV +AIVQ------------AALPQGIVPFVFAKEYNVHPAILSTGVI---------------- +-FG-MLI-A-LPITL--------------------------------------------- +-------------------------------------------------------VYY +>_seed_PINI_ARATH/9-617 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------HVMTAMVPLYVAMILA- +YGSVKWWKIFTPDQCSGINRFVALFA-----------VPLLSFHFIAANNPYA------- +---MNLRFLAADSLQKVIVLSLLFLWCKLSR---NGSLDWTITLFSLSTLPNTLVMGIPL +LKGMYGN----------------------------------FSGDLMVQIVVLQCIIWYT +LML------------------FLFEYRGAKLLISEQFP-DTAGSIVSIHVDSDIMSLDGR +Q-PLETEAEIKEDGKLHVTVRRSNASRSDIYS-----RRSQGL-SATPRPSNLTNAEIYS +LQSSRNPTPRGSSFNHTDFY---------------SMMASGGGRNSNFGPGEA------- +--------VFGSKGPTPRPSNYEEDGGPAKPTAAGTAAGAGRFHYQSGGSGGGGGAHYPA +PNPGMFSPNTGGGGGTAAKGNAPVVGGKRQDGN------GRDLHMFVWSSSASPVSDVFG +GGGGNHHADYSTATNDHQKDVKISVPQGNSNDNQYVEREEFSFGNKDDDSKVLATDGGNN +ISNKTTQAKVMPPTSVMTRLILIMVWRKLIRNPNSYSSLFGITWSLI-SFKWNIEMP--- +---ALIAKSISILSDAGLGMAMFSL--------GL------------------------- +---FMALNPRIIACGNRRAAFA--------AAMRFVVGPAVMLVASYAVGLRGV--LLHV +AIIQ------------AALPQGIVPFVFAKEYNVHPDILSTAVI---------------- +-FG-MLI-A-LPITL--------------------------------------------- +-------------------------------------------------------LYY +>_seed_Q9FVF6_POPPZ/9-609 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------HVMTAMVPLYVAMILA- +YGSVKWWKIFTPDQCSGINRFVALFA-----------VPLLSFHFISTNDPYN------- +---MNLRFITADSLQKVIVLVVLALWTKLSK---RGCLEWTITLFSLSTLPNTLVMGIPL +LKGMYGD----------------------------------YSGSLMVQVVVLQCIIWYT +LML------------------FMFEYRGAKLLISEQFP-DTAGSIVSIHVDSDIMSLDGR +Q-PLETEAAIKEDGKLHVTVRKSNASRSDIFS-----RRSQGLSSTTPRPSNLTNAEIYS +LQSSRNPTPRGSSFNHTDFY---------------SMMA--AGRNSNFGASDVY------ +-------GLSASRGPTPRPSNFEEEHGGSNKPRFHHYHAPGGATHYPAPNPGMFSPTTAA +SKGVSANANNAAAAAAKKPNGQAQQKAED-------------GRDLHMFVWSSSASPVSD +VFGGHDYGAHDLKDVRVAVSPGKVEGQRENQEDYNLERDDFSFGNRGLDRERNSHEGEKG +GFD--GKPKAMPPTSVMTRLILIMVWRKLIRNPNTYSSLIGLIWSLV-SFRWNVKMP--- +---LIIAKSISILSDAGLGMAMFSL--------GL------------------------- +---FMALQPRIIACGNSIATFS--------MAVRFLTGPAIMAAASIAVGIRGT--LLHI +AIVQ------------AALPQGIVPFVFAKEYNVHPEILSTGVI---------------- +-FG-MLI-A-LPITL--------------------------------------------- +-------------------------------------------------------VYY +>_seed_B8AIF2_ORYSI/9-590 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------HVMTAMVPLYVAMILA- +YGSVKWWRIFTPDQCSGINRFVALFA-----------VPLLSFHFISTNNPYT------- +---MNLRFIAADTLQKLMVLAMLTAWSHLSR---RGSLEWTITLFSLSTLPNTLVMGIPL +LKGMYGE----------------------------------FSGSLMVQIVVLQCIIWYT +LML------------------FMFEYRGARMLITEQFP-DTAANIASIVVDPDVVSLDGR +RDAIETETEVKEDGRIHVTVRRSNASRSDIYS-----RRSMGFSSTTPRPSNLTNAEIYS +LQSSRNPTPRGSSFNHTDFY---------------SMV----GRSSNFGAADA------- +--------FGVRTGATPRPSNYEDDASKPKYPLPASNAAPMAGHYPAPNPAVSSAPKGAK +KAATNGQAKGEDLHMFVWSS-------------------------------SASPVSDVF +GGGAPDYNDAAAVKSPRKMDGAKDREDYVERDDFSFGNRGVMDRDAEAGDEKAAAAAGAD +PSKAMAAPTAMPPTSVMTRLILIMVWRKLIRNPNTYSSLIGLIWSLV-CFRWNFEMP--- +---AIVLKSISILSDAGLGMAMFSL--------GL------------------------- +---FMALQPHIIACGNKVATYA--------MAVRFLAGPAVMAAASFAVGLRGT--LLHV +AIVQ------------AALPQGIVPFVFAKEYSVHPSILSTAVI---------------- +-FG-MLI-A-LPITL--------------------------------------------- +-------------------------------------------------------VYY +>_seed_PIN6_ARATH/9-565 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------TVMCAMAPLYFAMFVA- +YGSVKWCKIFTPAQCSGINRFVSVFA-----------VPVLSFHFISQNNPYK------- +---MDTMFILADTLSKIFVFVLLSLWAVFFK---AGGLDWLITLFSIATLPNTLVMGIPL +LQAMYGD----------------------------------YTQTLMVQLVVLQCIIWYT +LLL------------------FLFELRAARLLIRAEFPGQAAGSIAKIQVDDDVISLDGM +D-PLRTETETDVNGRIRLRIRRSVSSVPDSVMSSSLC--------LTPRASNLSNAEIFS +VN----------TPNNRFFHGGGGSGTLQFYNGSNEIMF-CNGDLGGFGFTRPGLGASPR +RLSGYASSDAYSLQPTPRASNFNELDVNGNGTPVWMKSPAAGRIYRQSSPKMMWESGQRH +AAK--------------------------------------------------------- +---------DINGSVPEKEISFRDALKAAPQATAAGGGASMEEGAAGKDTTPVA-AIG-K +-QE-------MPSAIVMMRLILTVVGRKLSRNPNTYSSLLGLVWSLI-SFKWNIPMP--- +---NIVDFSIKIISDAGLGMAMFSL--------GL------------------------- +---FMALQPKMIPCGAKKATMG--------MLIRFISGPLFMAGASLLVGLRGS--RLHA +AIVQ------------AALPQGIVPFVFAREYNLHPDLLSTLVI---------------- +-FG-MIV-S-LPVTI--------------------------------------------- +-------------------------------------------------------LYY +>_seed_YFDV_ECOLI/4-307 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------FFIGDLLPIIVIMLLG- +YFSGRR-ETFSEDQARAFNKLVLNYA-----------LPAALFVSITRANREM------- +---IFADTRLTLVSLVVIVGCFFFSWFGCYK-FFKRTHAEAAVCALIAGSPTIGFLGFAV +LDPIYGD----------------------SV---------STGLVVAIISIIVNAITIPI +GLY------------------LLNPSSGADGKK--------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +-------------------NSNLSALISAAKEPVVWAPVLATILVLV-GVKIP------- +---AAWDPTFNLIAKANSGVAVFAA--------GL------------------------- +---TLAAHKFEFSAEIAYN-----------TFLKLILMPLALLLVGMACHLNSE--HLQM +MVLA------------GALPPAFSGIIIASRFNVYTRTGTASLA---------------- +-VS-VLG-F-VVTAP--------------------------------------------- +-------------------------------------------------------LWI +>_seed_YWKB_BACSU/5-315 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------DILILLAPIFFVIVLG- +WFAGHF-GSYDAKSAKGVSTLVTKYA-----------LPAHFIAGILTTSRSE------- +---FLSQVPLMISLIIGIVGFYIIILLVCRF-IFKYDLTNSSVFSLNSAQPTFAFMGIPV +LGSLFGA----------------------------------NEVAIPIAVTGIVVNAILD +PLA------------------IIIATVGESSKKNEESGD--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------SFWKMTGKSILHGLCEPLAAAPLISMILVLVFNFTLP------- +---ELGVKMLDQLGSTTSGVALFAV--------GV------------------------- +---TVGIRKIKLSMPAIG-----------IALLKVAVQPALMFLIALAIGLPAD-QTTKA +ILL-------------VAFPGSAVAAMIATRFEKQEEETATAFV---------------- +-VS-AIL-S-LISLP--------------------------------------------- +-------------------------------------------------------III +>_seed_P71425_KLEPN/4-313 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------VIIHALAPIFVIMLLG- +FWAGKA-GMVDNKNVSLLNIFVMDFA-----------LPATLFSATVQTPWAG------- +---IVAQSPLVLVLTGAMWITYAAIYFLATS-VFKRTPQDGAVLTLTVALPNYAALGLPI +LGSVLGE---------------------------------GASTSLSVAVSIACGSVLMT +PFC------------------LLILEREKARAAGENSG---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------STLAMLPVLMWRSVKKPIVWGPLLGVVLSAI-GIKMP------- +---DLLLASIKPLGLAATAAALFLT--------GV------------------------- +---ILSARKLQLNALIAAS-----------TIVKLLVQPFIAWGLVMLLGLHGS-IAITA +ILM-------------IALAAGFFGVVFGNRFGVQSPDAEAVLL---------------- +-LS-SVL-C-ILSLP--------------------------------------------- +-------------------------------------------------------LFI +>_seed_Q98L58_RHILO/3-308 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------PLTETVLFVFSLVALG- +YLAGLT-GYLRPASGEGISDFAVSVA-----------MPLLLFQTMVKADFHG------- +-----VAPWPLWGAYFTAVAITWAAGHLVTTRIFGRDARAGVVGGVSSAYSNVVLLGAPF +ILGIFGP-----------------------S---------GFEVLSLLVSVHLPVMMMAS +IVL------------------FEMFGRGGGEHV--------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------HPLRVLRSFLRRLFINPLIIGILLGLAWRLS-GVPLP------- +---SLVMRLVDALANTAGPVALFAM--------GL------------------------- +---SLRRFGVSGNVRPALA----------LSALKLFLMPALVLAFVLLLGLPPL--TAKV +AVVV------------AALPSGINSYLIAVQFNTGQALASNQMT---------------- +-IA-TAC-A-AVTTA--------------------------------------------- +-------------------------------------------------------FWL +>_seed_O67397_AQUAE/2-289 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------FIYEKVFFILLIIAFA- +YTLKRG-GIFKEEHALPFINYVIYFA-----------LPFTIFKNLRF---LE------- +---IGKEVLGVVLIAWGAIFLSILFAFLFGK-FLKLEEKTLRAFLLVSSFGNTAFMGYPF +LYALEGN----------------------------------EGLKYAILYDQLGSFLMVI +TLG--------------------------------------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------LFLAIGKFDLKELILFPPFIALVLSFLLHGV-RFP--------- +---QFFEHSVEIISGSLIPVILFSL--------GL------------------------- +---RLNFTDMKSDYRTLFSA----------LFIKMFLVPLLILVFLKIFGLTSL--PYRV +ALIE------------SAMPPMVFAGVLALKYELDFRLAFSAIT---------------- +-LG-IVI-S-LFTVP--------------------------------------------- +-------------------------------------------------------VFR +>_seed_Q97M34_CLOAB/2-296 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------YVFEQIVILFLIMGIG- +YYAAKS-KIIDDDTTSHLSNFIVSIT-----------LPLMILTSFNVEYSRK------- +---TVITIINLLVFSVAAFIISIVIGKII---SFKFAMDKRDILMFMSIFSNCGFIGFPV +LKVVYGN----------------------------------KGVLYTSIFNLVYNVFIWT +IGI------------------VIINDKREKIDY--------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +--------------------------KKILFNHNIIAVIVGVFLMLL-SIKIP------- +---YVMSSAFNLIGSMTAPLSMIVI--------GS------------------------- +---ILA--------GVDFNDIFKDWSLYYIAILRLIIIPLIIYFALKPFQINKI--VIGV +IIIC------------EAMPGGTLCPILAKSCNRNFKYASKIVL---------------- +-IT-TIL-S-MMTIP--------------------------------------------- +-------------------------------------------------------FMT +>_seed_YB8B_YEAST/13-413 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------LVFESVLQVVIIALAG- +FWSASS-GLLPKQSQKIISLLNVDLF-----------TPCLIFSKLAKSLSMA------- +---KIFEIAIIPIFFGLTTGISFISGKIMSR-ILDLDKDETNFVVANSVFGNSNSLPVSL +TLSLAYTLPNLTW-D-----QIPNDNRDNVA---------SRGILYLLIFQQIGQMLRWS +WGY------------------NKLMKWSGENTQHMPPSQVQSLLERTPNIDNEELVNEEQ +EEQELLEEENNRMNSSFLSSSSIGDKIWQKSCTVFER----------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +--------------------------IRANLNPPLYSMIFAVVVAAI-GPLQRELFMEDG +FINNTFAEAVTQLGSVSIPLILVVL--------GS------------------------- +---NLYPSA-----EVFPKTVHHSKLLIGSIIGRMILPSCFLLPIIAIAV------KYIN +VSILDDPIFLVVGFLLTVSPPAIQLTQITQLNEFFEAEMADILF---------------- +-WG-YAV-L-SLPVS--------------------------------------------- +-------------------------------------------------------IIV +>_seed_YDQ4_SCHPO/18-440 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------PIIESDLEVIVIALGG- +YVLAKK-GFLPRDAQKVISSLNVYFF-----------TPCLVFEKVGNGLNLK------- +---MLIDLSLLPVFYVIISAASILISFLLAK-LFRLTPRQRNFATACITFQNSNSLPLAL +VSSLATTVKDLLW-D-----KIPDDTPDKVA---------SRGIMYLLIFSQLGQALRWS +YGY------------------RILLSPNQPEDPLPIGNRSWSHSDVNEEEIQNLLASSAN +VDGVQNSVQANEGSTVQTDSSAISKNDNVQVETSNEEVGGFGAASSKISK---------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------------FIVLLLDFFSPPLYSLFIALFIAVV-PPLQRFFFEEGS +FVEGSITSGIRMAGQVAVPMILVVL--------GA------------------------- +---SLATDISKTEPTQEVRKNNDTRVIIVCLLGRMVVVPLALLPAFSLLS------YFSE +ISTVDDPVFVVVIFLLVGSPTAIQLTQICQLNGVFERECAKVLW---------------- +-WS-YAV-F-TPPNS--------------------------------------------- +-------------------------------------------------------LLL +>_seed_PILS4_ARATH/9-407 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------ASSKPVVETLLITSVGF +YLALDTVNLLGHDARKHLNNIVFYVF-----------SPSLIGSRLADSVTYE------- +---SLVKMWFMPVNVLLTFMIGSLLGWIVIV-ITKPPSQLRGLIISCCASGNLGTMPLII +IPAICKE-------K-----GGPFGDSESCE---------KYGMGYVTLSMT--AFFISV +YKHDTNWYVSGGNGLLMDLYINLMR------VLSNSPVETHTHSIESNYDDSCKVQLISS +K------------------------------------------EEEKEEDNHQVGRWEEV +KQ---------------------------------------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------RVVSLSKKVNLGSIFAPATIAAIIALVIGLI-TPLRNLIIGTVA +PF-RVIQDSLTLLGDGAIPAMTLIL--------GG------------------------- +---NLLKGMRRSEVRSSEMKNSCIIGV---LVARYILLPVSGVLLVRGAY-------KLD +LVTS-EPLYQFVLLLQYAVPPAMNLGTKTQLFGAGESECSVIML---------------- +-WT-YSL-A-AVSLT--------------------------------------------- +-------------------------------------------------------VWP +>_seed_PILS5_ARATH/9-388 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------VASMPVIQVLFMSLVGA +FMASDRCKLFPVEARNSMNKVVFVLF-----------APALMFANLAQTVTLE------- +---DIISWWFMPVNMGLTFLIGGLLGWLVVK-ILKPPPYLEGLIVATCSAGNMGNLPIIL +VPAICDE-------D-----KSPFGNRSVCR---------TVGLSYASFSMALGGFYIWT +YTF------------------RLIKGSAMKVQAIEESEKIAIKSSNSDLEADHKTHLLGA +P-----------------------------------------EDKENKVVKEKTGFWRKG +VD---------------------------------------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------FLHEI-----LEELLAPPTLGAIIGFIFGAV-RWLRNLIIGDDA +PL-RIVQSTAKLLGDGTIPCMTIIL--------GG------------------------- +---NLIQG-----LRSSAVKPMVVLGI---VCVRYIAMPIIGIGIVLTAA-------NLG +FLPA-DPLFQYVLMLQFTLPPAMNIGTMTQLYNVAQDECSVLML---------------- +-WT-YLV-A-ILALT--------------------------------------------- +-------------------------------------------------------VWS +>_seed_PILS2_ARATH/18-441 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------SGVVPLLKLICLTVIGL +LLAHPKTQLVPRATFRLLSKLVFALF-----------LPCLIFTELGESITLD------- +---NIVQWWFIPVNVLLSAVVGSLIGYLVVL-ICRPPPEFNRFTIVMTAFGNTGNLLLAI +VSSVCHT--------------KTNPFGPNCN---------SRGVSYVSFAQWVAVILVYT +VVY------------------HMMEPPLEYYEVVEEEG-VEIEEINVENHDASRPLLVEA +EWPGIEDKETEHCKTPFIARVFNSISSFSQTSFPEVDLGGEYGGESSSPRSIQCLAEPRV +MR---------------------------------------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------RIRVVAEQTPVKHILQPPTIASLLAIIIGSV-PQLKSVVFGYDA +PL-SFITDSLNIMGSAMVPSVMLVL--------GG------------------------- +---MLSEGPNESTLGLRTTIGI--------SVARLLVLPLVGIGIVMSAD-------KLG +LISSADPMFKFVLLLQYSTPSAILLGAIASLRGYAVREASALLF---------------- +-WQ-HIF-A-LLSLT--------------------------------------------- +-------------------------------------------------------FYI +>_seed_PILS6_ARATH/30-423 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------IAVMPIAKVFTMCFLGL +LMASKYVNILPPSGRKLLNGLVFSLL-----------LPCLIFSQLGQAVTLQ------- +---KMLQWWFIPVNVVLGTISGSIIGFIVAS-IVRPPYPYFKFTIIQIGVGNIGNVPLVL +LAALCRD-------T-----SNPFGDSEKCS---------IDGTAYISFGQWVGAIILYT +YVY------------------QMFAPPPEGFDAEEENLALKTLPVDAAPEQVPLLTQNFP +KDFSPTQDL--------------------------------LPVQSTEPRGRGVSRKGKI +AQ---------------------------------------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------IFVFLYEKLKLKQIVQPAIVASILAMILGAI-PFTKKLIFTNGA +PL-FFFTDSCMILGDAMIPCILLAL--------GG------------------------- +---NLINGPGSSKLGFKTTAAI--------IIGRLVLVPPVGLGIVTVAD-------KLG +FLPADDKMFRFVLLLQHTMPTSVLSGAVANLRGCG-RESAAVLF---------------- +-WV-HIF-A-IFSMA--------------------------------------------- +-------------------------------------------------------GWM +>_seed_PIN4_ARATH/9-611 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------TVLTAVVPLYVAMILA- +YGSVQWWKIFSPDQCSGINRFVAIFA-----------VPLLSFHFISTNDPYA------- +---MNFRFVAADTLQKIIMLVLLALWANLTK---NGSLEWMITIFSLSTLPNTLVMGIPL +LIAMYGT----------------------------------YAGSLMVQVVVLQCIIWYT +LLL------------------FLFEYRGAKLLIMEQFP-ETGASIVSFKVESDVVSLDGH +D-FLETDAEIGNDGKLHVTVRKSNASRRSLMM--------------TPRPSNLTGAEIYS +LS----STPRGSNFNHSDFY---------------SVMGFPGGRLSNFGPADLY------ +-------SVQSSRGPTPRPSNFEENNAVKYGFYNNTNSSVPAAGSYPAPNPEFSTGTGVS +TKPNKIPKENQQQLQEKDSKASHDAKELHMFVWSSSASPVSDVFGGGAGDNVATEQSEQG +AKEIRMVVSDQPRKSNARGGGDDIGGLDSGEGEREIEKATAGLNKMGSNSTAELEAAG-G +-DGGGNNGTHMPPTSVMTRLILIMVWRKLIRNPNTYSSLIGLIWALV-AYRWHVAMP--- +---KILQQSISILSDAGLGMAMFSL--------GL------------------------- +---FMALQPKIIACGNSVATFA--------MAVRFITGPAIMAVAGIAIGLHGD--LLRI +AIVQ------------AALPQGIVPFVFAKEYNVHPTILSTGVI---------------- +-FG-MLI-A-LPITL--------------------------------------------- +-------------------------------------------------------VYY +>_seed_PIN7_ARATH/9-614 +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------------------TVLTAVIPLYVAMILA- +YGSVRWWKIFSPDQCSGINRFVAIFA-----------VPLLSFHFISSNNPYA------- +---MNLRFIAADTLQKLIMLTLLIIWANFTR---SGSLEWSITIFSLSTLPNTLVMGIPL +LIAMYGE----------------------------------YSGSLMVQIVVLQCIIWYT +LLL------------------FLFEYRGAKILIMEQFP-ETGASIVSFKVESDVVSLDGH +D-FLETDAQIGDDGKLHVTVRKSNASRRSFYG--------GGGTNMTPRPSNLTGAEIYS +L----NTTPRGSNFNHSDFY---------------SMMGFPGGRLSNFGPADMY------ +-------SVQSSRGPTPRPSNFEESCAMASSPRFGYYPGGAPGSYPAPNPEFSTGNKTGS +KAPKENHHHVGKSNSNDAKELHMFVWGSNGSPV-----SDRAGLQVDNGANEQVGKSDQG +GAKEIRMLISDHTQNGENKAGPMNGDYGGEEESERVKEVPNGLHKLRCNSTAELNPKEAI +ETGETVPVKHMPPASVMTRLILIMVWRKLIRNPNTYSSLIGLIWALV-AFRWDVAMP--- +---KIIQQSISILSDAGLGMAMFSL--------GL------------------------- +---FMALQPKLIACGNSTATFA--------MAVRFFTGPAVMAVAAMAIGLRGD--LLRV +AIVQ------------AALPQGIVPFVFAKEYNVHPAILSTGVI---------------- +-FG-MLI-A-LPITL--------------------------------------------- +-------------------------------------------------------VYY +> 1== M63632 1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91] +----------MN-------------------GTEGDNFYV---------------P---- +-------------------------FSNKTGLARSPYEYPQY------------------ +----------------YLAEPW-------------------KYSALAAYMFFLILVGFPV +NFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLF-GFTVTMYTSMN-GYFV--FGPTMC +SIEGFFATLGGEVALWSLVVLAIERYIVICKPMGNF-RFGNTHAIMGVAFTWIMALACAA +P-PLVG------WSR-----YIPEGMQCSCGPDYYTLNPNFNNESYVVYMFVVHFLVPFV +IIF--------------FCYGRLLCTVKEAAAAQQESA---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---------STQKAEKEVTRMV----VLMVIGFLVCWVPYASVAFYIFTHQGS---DFGA +TFMT--------LPAFFAKSSALYNPVIYILMNKQFRNCMITTL-----CC---GKNPLG +DDE-SGA-S-TSK-TEVSSVS-TSPVSPA------------------------------- +---------------------------------------------------------- +> 2== U22180 1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94] +----------MN-------------------GTEGPNFYV---------------P---- +-------------------------FSNITGVVRSPFEQPQY------------------ +----------------YLAEPW-------------------QFSMLAAYMFLLIVLGFPI +NFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFG-GFTTTLYTSLH-GYFV--FGPTGC +NLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSNF-RFGENHAIMGVAFTWVMALACAA +P-PLVG------WSR-----YIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMI +VIF--------------FCYGQLVFTVKEAAAQQQESA---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---------TTQKAEKEVTRMV----IIMVIFFLICWLPYASVAMYIFTHQGS---NFGP +IFMT--------LPAFFAKTASIYNPIIYIMMNKQFRNCMLTSL-----CC---GKNPLG +DDE-ASA-T-ASK-TETSQVA-PA------------------------------------ +---------------------------------------------------------- +> 3== M92038 1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9 +----------MN-------------------GTEGINFYV---------------P---- +-------------------------MSNKTGVVRSPFEYPQY------------------ +----------------YLAEPW-------------------KYRLVCCYIFFLISTGLPI +NLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACF-GFTVTFYTAWN-GYFV--FGPVGC +AVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGNF-RFSATHAMMGIAFTWVMAFSCAA +P-PLFG------WSR-----YMPEGMQCSCGPDYYTHNPDYHNESYVLYMFVIHFIIPVV +VIF--------------FSYGRLICKVREAAAQQQESA---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---------TTQKAEKEVTRMV----ILMVLGFMLAWTPYAVVAFWIFTNKGA---DFTA +TLMA--------VPAFFSKSSSLYNPIIYVLMNKQFRNCMITTI-----CC---GKNPFG +DEDVSSTVS-QSK-TEVSSVS-SSQVSPA------------------------------- +---------------------------------------------------------- +> 4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish +----------MN-------------------GTEGKNFYV---------------P---- +-------------------------MSNRTGLVRSPFEYPQY------------------ +----------------YLAEPW-------------------QFKILALYLFFLMSMGLPI +NGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCF-GFTVTFYTAIN-GYFV--LGPTGC +AVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSSHAFAGIAFTWVMALACAA +P-PLFG------WSR-----YIPEGMQCSCGPDYYTLNPDYNNESYVIYMFVCHFILPVA +VIF--------------FTYGRLVCTVKAAAAQQQDSA---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---------STQKAEREVTKMV----ILMVFGFLIAWTPYATVAAWIFFNKGA---DFSA +KFMA--------IPAFFSKSSALYNPVIYVLLNKQFRNCMLTTI-----FC---GKNPLG +DDE-SSTVS-TSK-TEVSSVS-PA------------------------------------ +---------------------------------------------------------- +> 5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish +----------MN-------------------GTEGNNFYV---------------P---- +-------------------------LSNRTGLVRSPFEYPQY------------------ +----------------YLAEPW-------------------QFKLLAVYMFFLICLGLPI +NGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCF-GFTVTFYTAIN-GYFA--LGPTGC +AVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSTHASAGIAFTWVMAMACAA +P-PLVG------WSR-----YIPEGIQCSCGPDYYTLNPEYNNESYVLYMFICHFILPVT +IIF--------------FTYGRLVCTVKAAAAQQQDSA---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---------STQKAEREVTKMV----ILMVLGFLVAWTPYATVAAWIFFNKGA---AFSA +QFMA--------IPAFFSKTSALYNPVIYVLLNKQFRSCMLTTL-----FC---GKNPLG +DEE-SSTVS-TSK-TEVSSVS-PA------------------------------------ +---------------------------------------------------------- +> 6== L11864 1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208- +----------MKQVPE-----------------FHEDFYI---------------P---- +-----------------------IPLDINNLSAYSPFLVPQD------------------ +----------------HLGNQG-------------------IFMAMSVFMFFIFIGGASI +NILTILCTIQFKKLRSHLNYILVNLSIANLFVAIF-GSPLSFYSFFN-RYFI--FGATAC +KIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGNF-TFKTPHAIAGCILPWISALAASL +P-PLFG------WSR-----YIPEGLQCSCGPDWYTTNNKYNNESYVMFLFCFCFAVPFG +TIV--------------FCYGQLLITLKLAAKAQADSA---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---------STQKAEREVTKMV----VVMVLGFLVCWAPYASFSLWIVSHRGE---EFDL +RMAT--------IPSCLSKASTVYNPVIYVLMNKQFRSCMMKMV-----C----GKN-IE +EDE-AST-S-SQV-TQVSSVA-PEK----------------------------------- +---------------------------------------------------------- +> 7== M13299 1 human BCP <>[Science232(4747),193-202'86] +----------MRKMS-------------------EEEFYL-------------------- +---------------------------FKNISSVGPWDGPQY------------------ +----------------HIAPVW-------------------AFYLQAAFMGTVFLIGFPL +NAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIF-SVFPVFVASCN-GYFV--FGRHVC +ALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNF-RFSSKHALTVVLATWTIGIGVSI +P-PFFG------WSR-----FIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLS +LIC--------------FSYTQLLRALKAVAAQQQESA---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---------TTQKAEREVSRMV----VVMVGSFCVCYVPYAAFAMYMVNNRNH---GLDL +RLVT--------IPSFFSKSACIYNPIIYCFMNKQFQACIMKMV-----C----GKA-MT +DES-DTC-S-SQK-TEVSTVS-STQVGPN------------------------------- +---------------------------------------------------------- +> 8=opsin, greensensitive human (fragment) S07060 +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +----------------------------DLAETVI-ASTISIVNQVS-GYFV--LGHPMC +VLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIVGIAFSWIWAAVWTA +P-PIFG------WSR-----YWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLS +IIV--------------LCYLQVWLAIRAVAKQQKESE---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---------STQKAEKEVTRMV----VVMVLAFC-------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +---------------------------------------------------------- +> 9== K03494 1 human GCP <>[Science232(4747),193-202'86] +----------MAQQWSLQRLAGRHPQDSYEDSTQSSIFTY-------------------- +---------------------------TNSNSTRGPFEGPNY------------------ +----------------HIAPRW-------------------VYHLTSVWMIFVVIASVFT +NGLVLAATMKFKKLRHPLNWILVNLAVADLAETVI-ASTISVVNQVY-GYFV--LGHPMC +VLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNV-RFDAKLAIVGIAFSWIWAAVWTA +P-PIFG------WSR-----YWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLS +IIV--------------LCYLQVWLAIRAVAKQQKESE---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---------STQKAEKEVTRMV----VVMVLAFCFCWGPYAFFACFAAANPGY---PFHP +LMAA--------LPAFFAKSATIYNPVIYVFMNRQFRNCILQLF----------GKK-VD +DGS-ELS-S-ASK-TEVSSVS---SVSPA------------------------------- +---------------------------------------------------------- +> 10== Z68193 1 human Red Opsin <>[] +----------MAQQWSLQRLAGRHPQDSYEDSTQSSIFTY-------------------- +---------------------------TNSNSTRGPFEGPNY------------------ +----------------HIAPRW-------------------VYHLTSVWMIFVVTASVFT +NGLVLAATMKFKKLRHPLNWILVNLAVADLAETVI-ASTISIVNQVS-GYFV--LGHPMC +VLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIVGIAFSWIWSAVWTA +P-PIFG------WSR-----YWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLA +IIM--------------LCYLQVWLAIRAVAKQQKESE---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---------STQKAEKEVTRMV----VVMIFAYCVCWGPYTFFACFAAANPGY---AFHP +LMAA--------LPAYFAKSATIYNPVIYVFMNRQFRNCILQLF----------GKK-VD +DGS-ELS-S-ASK-TEVSSVS---SVSPA------------------------------- +---------------------------------------------------------- +> 11== M92036 1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92] +----------MTEAWNVAVFAARRSRDD-DDTTRGSVFTY-------------------- +---------------------------TNTNNTRGPFEGPNY------------------ +----------------HIAPRW-------------------VYNLVSFFMIIVVIASCFT +NGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLV-ASTISVFNQIF-GYFI--LGHPLC +VIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGNI-KFDSKLAIIGIVFSWVWAWGWSA +P-PIFG------WSR-----YWPHGLKTSCGPDVFSGSVELGCQSFMLTLMITCCFLPLF +III--------------VCYLQVWMAIRAVAAQQKESE---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---------STQKAEREVSRMV----VVMIVAFCICWGPYASFVSFAAANPGY---AFHP +LAAA--------LPAYFAKSATIYNPVIYVFMNRQFRNCIMQLF----------GKK-VD +DGS-EAS-T-TSR-TEVSSVS-NSSVAPA------------------------------- +---------------------------------------------------------- +> 12== M62903 1 chicken visual pigment <>[BBRC173,1212-1217'90] +----------MA-AWE-AAFAARRRHEE-EDTTRDSVFTY-------------------- +---------------------------TNSNNTRGPFEGPNY------------------ +----------------HIAPRW-------------------VYNLTSVWMIFVVAASVFT +NGLVLVATWKFKKLRHPLNWILVNLAVADLGETVI-ASTISVINQIS-GYFI--LGHPMC +VVEGYTVSACGITALWSLAIISWERWFVVCKPFGNI-KFDGKLAVAGILFSWLWSCAWTA +P-PIFG------WSR-----YWPHGLKTSCGPDVFSGSSDPGVQSYMVVLMVTCCFFPLA +III--------------LCYLQVWLAIRAVAAQQKESE---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---------STQKAEKEVSRMV----VVMIVAYCFCWGPYTFFACFAAANPGY---AFHP +LAAA--------LPAYFAKSATIYNPIIYVFMNRQFRNCILQLF----------GKK-VD +DGS-EVS-T--SR-TEVSSVS-NSSVSPA------------------------------- +---------------------------------------------------------- +> 13== S75720 1 chicken P-opsin <>[Science267(5203),1502-1506'95] +---------------------------------MSSNSSQ-------------------- +---------------------------APPNGTPGPFDGPQW------------------ +---------------PYQAPQS-------------------TYVGVAVLMGTVVACASVV +NGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLC-GSSVSLSNNIN-GFFV--FGRRMC +ELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGDF-QFQRRHAVSGCAFTWGWALLWSA +P-PLLG------WSS-----YVPEGLRTSCGPNWYTGGSN--NNSYILSLFVTCFVLPLS +LIL--------------FSYTNLLLTLRAAAAQQKEAD---------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---------TTQRAEREVTRMV----IVMVMAFLLCWLPYSTFALVVATHKGI---IIQP +VLAS--------LPSYFSKTATVYNPIIYVFMNKQFQSCLLEML-----CCGYQPQR-TG +KAS-PGT-P-GPH-ADVTAAGLRNKVMPAH------------------------------ +-----------P---------------------------------------------V +> 14== M17718 1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87] +----------MESGN------------------VSSSLF--------------------- +-------------------------------GNVSTALRPEA------------RLSA-- +-ETRLLGWNVPPEELRHIPEHWLTYP----------EPPESMNYLLGTLYIFFTLMSMLG +NGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIFIYNSFH-QGYA--LGHLGC +QIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIAMIIFIYMYATPWVV +A-CYTET-----WGR-----FVPEGYLTSCTFDYLTDN--FDTRLFVACIFFFSFVCPTT +MIT--------------YYYSQIVGHVFSHEKALRDQAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---KMNVESLRS------------------------------------------------ +-----NVDKNKETAEIRIAKAA----ITICFLFFCSWTPYGVMSLIGAFGDKT---LLTP +GATM--------IPACACKMVACIDPFVYAISHPRYRMELQKRCPWL--ALNEKAPE--- +-SS-AVA-S-TSTTQEP-----QQTTAA-------------------------------- +---------------------------------------------------------- +> 15== X65879 1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92 +----------MEYHN------------------VSSVL---------------------- +-------------------------------GNVSSVLRPDA------------RLSA-- +-ESRLLGWNVPPDELRHIPEHWLIYP----------EPPESMNYLLGTLYIFFTVISMIG +NGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIFIYNSFH-QGYA--LGHLGC +QIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIAMIIFIYLYATPWVV +A-CYTES-----WGR-----FVPEGYLTSCTFDYLTDN--FDTRLFVACIFFFSFVCPTT +MIT--------------YYYSQIVGHVFSHEKALRDQAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---KMNVDSLRS------------------------------------------------ +-----NVDKSKEAAEIRIAKAA----ITICFLFFASWTPYGVMSLIGAFGDKT---LLTP +GATM--------IPACTCKMVACIDPFVYAISHPRYRMELQKRCPWL--AISEKAPE--- +-SR-AAI-S-TSTTQEQ-----QQTTAA-------------------------------- +---------------------------------------------------------- +> 16== M17730 1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87] +----------MEPLC--------------------------------------------- +-------------------------------NASEPPLRPEA------------R-SSGN +GDLQFLGWNVPPDQIQYIPEHWLTQL----------EPPASMHYMLGVFYIFLFCASTVG +NGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF--NSFH-RGFAIYLGNTWC +QIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPWVV +L-PLTQF-----WDR-----FVPEGYLTSCSFDYLSDN--FDTRLFVGTIFFFSFVCPTL +MIL--------------YYYSQIVGHVFSHEKALREQAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---KMNVESLRS------------------------------------------------ +-----NVDKSKETAEIRIAKAA----ITICFLFFVSWTPYGVMSLIGAFGDKS---LLTQ +GATM--------IPACTCKLVACIDPFVYAISHPRYRLELQKRCPWL--GVNEKSGE--- +-IS-SAQ-S-TTTQEQQ-----QTTAA--------------------------------- +---------------------------------------------------------- +> 17== X65880 1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92 +----------MDALC--------------------------------------------- +-------------------------------NASEPPLRPEA------------RMSSGS +DELQFLGWNVPPDQIQYIPEHWLTQL----------EPPASMHYMLGVFYIFLFFASTLG +NGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIFIYNSFH-RGFA--LGNTWC +QIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPWVV +L-PLTQF-----WDR-----FVPEGYLTSCSFDYLSDN--FDTRLFVGTIFLFSFVVPTL +MIL--------------YYYSQIVGHVFNHEKALREQAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---KMNVESLRS------------------------------------------------ +-----NVDKSKETAEIRIAKAA----ITICFLFFVSWTPYGVMSLIGAFGDKS---LLTP +GATM--------IPACTCKLVACIEPFVYAISHPRYRMELQKRCPWL--GVNEKSGE--- +-AS-SAQ-S-TTTQEQT-----QQTSAA-------------------------------- +---------------------------------------------------------- +> 18== D50584 1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1 +----------MTNAT-------------------GPQMAY-------------------- +-----------------------------YGAASMDFGYPE-------------GVSIVD +--------FVRPEIKPYVHQHWYNYP----------PVNPMWHYLLGVIYLFLGTVSIFG +NGLVIYLFNKSAALRTPANILVVNLALSDLIMLTT-NVPFFTYNCFSGGVWM--FSPQYC +EIYACLGAITGVCSIWLLCMISFDRYNIICNGFNGP-KLTTGKAVVFALISWVIAIGCAL +P-PFFG------WGN-----YILEGILDSCSYDYLTQD--FNTFSYNIFIFVFDYFLPAA +IIV--------------FSYVFIVKAIFAHEAAMRAQAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---KMNVSTLRS------------------------------------------------ +------NEADAQRAEIRIAKTA----LVNVSLWFICWTPYALISLKGVMGDTS---GITP +LVST--------LPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWF--CVHETETK-SN +DDS-QSN-S-TVAQDKA------------------------------------------- +---------------------------------------------------------- +> 19== D50583 1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1 +----------MANVT-------------------GPQMAF-------------------- +-----------------------------YGSGAATFGYPE-------------GMTVAD +--------FVPDRVKHMVLDHWYNYP----------PVNPMWHYLLGVVYLFLGVISIAG +NGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTT-NFPPFCYNCFSGGRWM--FSGTYC +EIYAALGAITGVCSIWTLCMISFDRYNIICNGFNGP-KLTQGKATFMCGLAWVISVGWSL +P-PFFG------WGS-----YTLEGILDSCSYDYFTRD--MNTITYNICIFIFDFFLPAS +VIV--------------FSYVFIVKAIFAHEAAMRAQAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---KMNVTNLRS------------------------------------------------ +------NEAETQRAEIRIAKTA----LVNVSLWFICWTPYAAITIQGLLGNAE---GITP +LLTT--------LPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWF--CVHEKDPN-DV +EEN-QSS-N-TQTQEKS------------------------------------------- +---------------------------------------------------------- +> 20== K02320 1 D.melanogaster opsin <>[Cell40,851-858'85] +----------MESFA--------------------------------------------- +--------------------------------VAAAQLGPHFAPLS--------NGSVVD +--------KVTPDMAHLISPYWNQFP----------AMDPIWAKILTAYMIMIGMISWCG +NGVVIYIFATTKSLRTPANLLVINLAISDFGIMIT-NTPMMGINLYF-ETWV--LGPMMC +DIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKM------------ +--------------------YVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLF +LIC--------------YSYWFIIAAVSAHEKAMREQAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---KMNVKSLRS------------------------------------------------ +------SEDAEKSAEGKLAKVA----LVTITLWFMAWTPYLVINCMGLFKF-E---GLTP +LNTI--------WGACFAKSAACYNPIVYGISHPKYRLALKEKCPCC--VFGKVDDG-KS +SDA-QSQ-A-TASEAES-----KA------------------------------------ +---------------------------------------------------------- +> 21== K02315 1 D.melanogaster ninaE <>[Cell40,839-850'85] +----------MESFA--------------------------------------------- +--------------------------------VAAAQLGPHFAPLS--------NGSVVD +--------KVTPDMAHLISPYWNQFP----------AMDPIWAKILTAYMIMIGMISWCG +NGVVIYIFATTKSLRTPANLLVINLAISDFGIMIT-NTPMMGINLYF-ETWV--LGPMMC +DIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYIWFMSSIWCL +A-PAFG------WSR-----YVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLF +LIC--------------YSYWFIIAAVSAHEKAMREQAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---KMNVKSLRS------------------------------------------------ +------SEDAEKSAEGKLAKVA----LVTITLWFMAWTPYLVINCMGLFKF-E---GLTP +LNTI--------WGACFAKSAACYNPIVYGISHPKYRLALKEKCPCC--VFGKVDDG-KS +SDA-QSQ-A-TASEAES-----KA------------------------------------ +---------------------------------------------------------- +> 22== X65877 1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204' +----------MDSFA--------------------------------------------- +--------------------------------AVATQLGPQFAAPS--------NGSVVD +--------KVTPDMAHLISPYWDQFP----------AMDPIWAKILTAYMIIIGMISWCG +NGVVIYIFATTKSLRTPANLLVINLAISDFGIMIT-NTPMMGINLYF-ETWV--LGPMMC +DIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYIWFMSTIWCC +LAPVFG------WSR-----YVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLF +LIC--------------YSYWFIIAAVSAHEKAMREQAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---KMNVKSLRS------------------------------------------------ +------SEDADKSAEGKLAKVA----LVTISLWFMAWTPYLVINCMGLFKF-E---GLTP +LNTI--------WGACFAKSAACYNPIVYGISHPKYRLALKEKCPCC--VFGKVDDG-KS +SEA-QSQ-A-TTSEAES-----KA------------------------------------ +---------------------------------------------------------- +> 23== M12896 1 D.melanogaster Rh2 <>[Cell44,705-710'86] +----------MERSH--------------------------------------------- +---------------------------LPETPFDLAHSGPRFQAQSSG------NGSVLD +--------NVLPDMAHLVNPYWSRFA----------PMDPMMSKILGLFTLAIMIISCCG +NGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMAS-QSPVMIINFYY-ETWV--LGPLWC +DIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKILFIWMMAVFWTV +M-PLIG------WSA-----YVPEGNLTACSIDYMTRM--WNPRSYLITYSLFVYYTPLF +LIC--------------YSYWFIIAAVAAHEKAMREQAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---KMNVKSLRS------------------------------------------------ +------SEDCDKSAEGKLAKVA----LTTISLWFMAWTPYLVICYFGLFKI-D---GLTP +LTTI--------WGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMC--VFGNTDEP-KP +DAP-ASD-TETTSEADS-----KA------------------------------------ +---------------------------------------------------------- +> 24== X65878 1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92 +----------MERSL--------------------------------------------- +---------------------------LPEPPLAMALLGPRFEAQTGG------NRSVLD +--------NVLPDMAPLVNPHWSRFA----------PMDPTMSKILGLFTLVILIISCCG +NGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMAS-QSPVMIINFYY-ETWV--LGPLWC +DIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKIAFIWMMAVFWTI +M-PLIG------WSS-----YVPEGNLTACSIDYMTRQ--WNPRSYLITYSLFVYYTPLF +MIC--------------YSYWFIIATVAAHEKAMRDQAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---KMNVKSLRS------------------------------------------------ +------SEDCDKSAENKLAKVA----LTTISLWFMAWTPYLIICYFGLFKI-D---GLTP +LTTI--------WGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMC--VCGTTDEP-KP +DAP-PSD-TETTSEAES-----KD------------------------------------ +---------------------------------------------------------- +> 25== U26026 1 Apis mellifera long-wavelength rhodopsin <>[] +----------M------------------------------------------------- +----------------------------------IAVSGPSYEAFSYGGQARFNNQTVVD +--------KVPPDMLHLIDANWYQYP----------PLNPMWHGILGFVIGMLGFVSAMG +NGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFC-MSPPMVINCYY-ETWV--LGPLFC +QIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSGK-PLSINGALIRIIAIWLFSLGWTI +A-PMFG------WNR-----YVPEGNMTACGTDYFNRG--LLSASYLVCYGIWVYFVPLF +LII--------------YSYWFIIQAVAAHEKNMREQAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---KMNVASLRS------------------------------------------------ +------SENQNTSAECKLAKVA----LMTISLWFMAWTPYLVINFSGIFNL-V---KISP +LFTI--------WGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSL--AC-AAEPS-SD +AVS-TTS-G-TTTVTDN-----EKSNA--------------------------------- +---------------------------------------------------------- +> 26== L03781 1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93] +----------MANQL--------------------------------------------- +---------------------------------SYSSLGWPYQP----------NASVVD +--------TMPKEMLYMIHEHWYAFP----------PMNPLWYSILGVAMIILGIICVLG +NGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAF-MMPTMTSNCFA-ETWI--LGPFMC +EVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAAA-PLTHKKATLLLLFVWIWSGGWTI +L-PFFG------WSR-----YVPEGNLTSCTVDYLTKD--WSSASYVVIYGLAVYFLPLI +TMI--------------YCYFFIVHAVAEHEKQLREQAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---KMNVASLRA------------------------------------------------ +-----NADQQKQSAECRLAKVA----MMTVGLWFMAWTPYLIISWAGVFSSGT---RLTP +LATI--------WGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSL--ACGSGESG-SD +VKS-EAS-A-TTTMEEK-----PKIPEA-------------------------------- +---------------------------------------------------------- +> 27== X07797 1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88] +----------MVESTTL----------------VNQTWWY-------------------- +------------------------------------------------------NPTV-- +----------------DIHPHWAKFD----------PIPDAVYYSVGIFIGVVGIIGILG +NGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISAFM-KKWI--FGKVAC +QLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMIIFVWMWSIVWSV +G-PVFN------WGA-----YVPEGILTSCSFDYLSTD--PSTRSFILCMYFCGFMLPII +IIA--------------FCYFNIVMSVSNHEKEMAAMAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---RLNAKELRK------------------------------------------------ +-------AQAGASAEMKLAKIS----MVIITQFMLSWSPYAIIALLAQFGPAE---WVTP +YAAE--------LPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKE-CE +DAN-DAE-E-EVVASER--GG-ESRDAAQMKEMMAMMQKMQAQQAAYQP---PPPPQGYP +PQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA +> 28== X70498 1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93] +----------MGRDLR-----------------DNETWWY-------------------- +------------------------------------------------------NPSI-- +----------------VVHPHWREFD----------QVPDAVYYSLGIFIGICGIIGCGG +NGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFL-KKWI--FGFAAC +KVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAI +G-PIFG------WGA-----YTLEGVLCNCSFDYISRD--STTRSNILCMFILGFFGPIL +IIF--------------FCYFNIVMSVSNHEKEMAAMAK--------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---RLNAKELRK------------------------------------------------ +-------AQAGANAEMRLAKIS----IVIVSQFLLSWSPYAVVALLAQFGPLE---WVTP +YAAQ--------LPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKE-TE +DDK-DAE-T-EIPAGESSDAA-PSADAAQMKEMMAMMQKMQQQQAAYPPQGYAPPPQGYP +PQGYPPQGY--PPQGYPPQGYPP---PPQGAPPQGAPP------AAPPQGVDNQAYQA +> 29== L21195 1 human serotonin 5-HT7 receptor protein <placenta and fetal bra +M---------MDVNS------------------SGRPDLYGHLRSFLLPEVGRGLPDLSP +DG------------GADPVAGSW---------------APHLLS----------EVTAS- +-----------------PAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAG +NCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVA-VMPFVSVTDLIGGKWI--FGHFFC +NVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITL +P-PLFG------WAQ-----NVNDDKVCLIS----------QDFGYTIYSTAVAFYIPMS +VML--------------FMYYQIYKAARKSAAKHKFPGF--------------------- +------------------------------------------------------------ +--------PR----------------------VEPDSVIALNG----------------- +------------------------------------------------------------ +-----------------------------------IV----------------------- +------------------------------------------------------------ +------------------------------------------------------------ +---KLQKE-------------------VEECA-NL-----------------SRLL---- +--KHERKNISIFKREQKAATTL----GIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPL +WVER--------TFLWLGYANSLINPFIYAFFNRDLRTTYRSLL-----QCQYRNINRKL +SAA-GMH-E-ALKLAER-----PERPEFVL------------QNADYCR----------- +-----KKGH--------------------------------------------DS--- +> 30== L15228 1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93] +------------------------------------------------------------ +--------------------------------------MPHLLSGF-------LEVTAS- +-----------------PAPTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIAG +NCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVA-VMPFVSVTDLIGGKWI--FGHFFC +NVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITL +P-PLFG------WAQ-----NVNDDKVCLIS----------QDFGYTIYSTAVAFYIPMS +VML--------------FMYYQIYKAARKSAAKHKFPGF--------------------- +------------------------------------------------------------ +--------PR----------------------VQPESVISLNG----------------- +------------------------------------------------------------ +-----------------------------------VV----------------------- +------------------------------------------------------------ +------------------------------------------------------------ +---KLQKE-------------------VEECA-NL-----------------SRLL---- +--KHERKNISIFKREQKAATTL----GIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPL +WVER--------TCLWLGYANSLINPFIYAFFNRDLRPTSRSLL-----QCQYRNINRKL +SAA-GMH-E-ALKLAER-----PERSEFVL------------QNSDHCG----------- +-----KKGH--------------------------------------------DT--- +> 31=p A47425 serotonin receptor 5HT-7 - rat +------------------------------------------------------------ +--------------------------------------MPHLLSGF-------LEVTAS- +-----------------PAPTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIAG +NCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVA-VMPFVSVTDLIGGKWI--FGHFFC +NVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITL +P-PLFG------WAQ-----NVNDDKVCLIS----------QDFGYTIYSTAVAFYIPMS +VML--------------FMYYQIYKAARKSAAKHKFPGF--------------------- +------------------------------------------------------------ +--------PR----------------------VQPESVISLNG----------------- +------------------------------------------------------------ +-----------------------------------VV----------------------- +------------------------------------------------------------ +------------------------------------------------------------ +---KLQKE-------------------VEECA-NL-----------------SRLL---- +--KHERKNISIFKREQKAATTL----GIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPL +WVER--------TCLWLGYANSLINPFIYAFFNRDLRTTYRSLL-----QCQYRNINRKL +SAA-GMH-E-ALKLAER-----PERSEFVL------------QNSDHCG----------- +-----KKGH--------------------------------------------DT--- +> 32== M83181 1 human serotonin receptor <>[JBC267(11),7553-7562'92] +----------MDVLS--------------------------------------------- +-----------------------------PGQGNNTTSPPAPFETG-------GNTTGIS +------------------------------------DVTVSYQVITSLLLGTLIFCAVLG +NACVVAAIALERSLQNVANYLIGSLAVTDLMVSVL-VLPMAALYQVL-NKWT--LGQVTC +DLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISI +P-PMLG------WRTPE---DRSDPDACTIS----------KDHGYTIYSTFGAFYIPLL +LML--------------VLYGRIFRAARFRIRKTVKKVE--------------------- +----------------------------------KTGADTRHGASPAPQPKK-------- +---------------------------------------SVNG-ESGSRNWRLGVESK-- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---AGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCA--PASFERKN +ERNAEAKRKMALARERKTVKTL----GIIMGTFILCWLPFFIVALVLPFCESS--CHMPT +LLGA--------IINWLGYSNSLLNPVIYAYFNKDFQNAFKKII-----KCKFCRQ---- +------------------------------------------------------------ +---------------------------------------------------------- +> 33=p A35181 serotonin receptor class 1A - rat +----------MDVFS--------------------------------------------- +-----------------------------FGQGNNTTASQEPFGTG-------GNVTSIS +------------------------------------DVTFSYQVITSLLLGTLIFCAVLG +NACVVAAIALERSLQNVANYLIGSLAVTDLMVSVL-VLPMAALYQVL-NKWT--LGQVTC +DLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISI +P-PMLG------WRTPE---DRSDPDACTIS----------KDHGYTIYSTFGAFYIPLL +LML--------------VLYGRIFRAARFRIRKTVRKVE--------------------- +----------------------------------KKGAGTSLGTSSAPPPKK-------- +---------------------------------------SLNG-QPGSGDWRRCAENR-- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +---AVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESGSNSYA--PACLERKN +ERNAEAKRKMALARERKTVKTL----GIIMGTFILCWLPFFIVALVLPFCESS--CHMPA +LLGA--------IINWLGYSNSLLNPVIYAYFNKDFQNAFKKII-----KCKFCRR---- +------------------------------------------------------------ +---------------------------------------------------------- +> 34== L06803 1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93] +MANFTFGDLALDVARM-----------------GGLASTPSGLRS-----TGLTTPGLSP +TGLVTSDFNDSYGLTGQFINGSHSSRSRDNASANDT------------------SATNM- +-----------------TDDRYWSLT----------VYSHEHLVLTSVILGLFVLCCIIG +NCFVIAAVMLERSLHNVANYLILSLAVADLMVAVL-VMPLSVVSEIS-KVWF--LHSEVC +DMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFISI +P-PLFG------WRDPN--NDPDKTGTCIIS----------QDKGYTIFSTVGAFYLPML +VMM--------------IIYIRIWLVARSRIRKDKFQMT-------KARLKTEETTLVAS +P---------KTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKK-------- +--------NRAKKL------------------PENANGVNSNS----------------- +--SS-------------------------------------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------SERLK------- +---QIQIETAEAFANGCAEEASIAML-ERQCNNGKKISSNDTPY---------------- +---SRTREKLELKRERKAARTL----AIITGAFLICWLPFFIIALIGPFVDPE---GIPP +FARS--------FVLWLGYFNSLLNPIIYTIFSPEFRSAFQKIL-----FGKYRRGHR-- +------------------------------------------------------------ +---------------------------------------------------------- +> 35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail +MANFTFGDLALDVARM-----------------GGLASTPSGLRS-----TGLTTPGLSP +TGLVTSDFNDSYGLTGQFINGSHSSRSRDNASANDT------------------SATNM- +-----------------TDDRYWSLT----------VYSHEHLVLTSVILGLFVLCCIIG +NCFVIAAVMLERSLHNVANYLILSLAVADLMVAVL-VMPLSVVSEIS-KVWF--LHSEVC +DMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFISI +P-PLFG------WRDPN--NDPDKTGTCIIS----------QDKGYTIFSTVGAFYLPML +VMM--------------IIYIRIWLVARSRIRKDKFQMT-------KARLKTEETTLVAS +P---------KTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKK-------- +--------NRAKKL------------------PENANGVNSNS----------------- +--SS-------------------------------------------------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------SERLK------- +---QIQIETAEAFANGCAEEASIAML-ERQCNNGKKISSNDTPY---------------- +---SRTREKLELKRERKAARTL----AIITGAFLICWLPFFIIALIGPFVDPE---GIPP +FARS--------FVLWLGYFNSLLNPIIYTIFSPEFRSAFQKIL-----FGKYRRGHR-- +------------------------------------------------------------ +---------------------------------------------------------- +> 36== X95604 1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi +----------MEGAE-------------------GQEEL--DWEA-----LYLRLP---- +---------------------------LQNCSWNSTGWEPNW------------NVTVV- +-----------------PNTTWWQAS-----APFDTPAALVRAAAKAVVLGLLILATVVG +NVFVIAAILLERHLRSAANNLILSLAVADLLVACL-VMPLGAVYEVV-QRWT--LGPELC +DMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRVGMMIACVWTVSFFVCI +A-QLLG------WKDPDWNQRVSEDLRCVVS----------QDVGYQIFATASSFYVPVL +IIL--------------ILYWRIYQTARKRIRRRRGATA--------------------- +----------------------------------------RGGVGPPPVPAG-------- +-----------------------------------GALVAGGG----------------- +------------------------------------------------------------ +------------------------------------------------------------ +------------------------------------------------------------ +-------------------------------SGGIAAAVVAVI-----GRPLP------- +---TISETTTTGFTNVSSNNTSPE---KQSCANGLEADPPTTGYGAVAAAYYPSLV---- +--RRKPKEAADSKRERKAAKTL----AIITGAFVACWLPFFVLAILVPTCD----CEVSP +VLTS--------LSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLL-----CGRRVRRRRA- +----------------------PQ------------------------------------ +----------------------------------------------------------
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/seed.aln Mon Jul 14 18:16:36 2025 +0000 @@ -0,0 +1,216 @@ +>PINI_ARATH/9-617 +HVMTAMVPLYVAMILA-YGSVKWWKIFTPDQCSGINRFVALFAVPLLSFHFIAANNPYAMNLRFLAADSLQK +VIVLSLLFLWCKLSR---NGSLDWTITLFSLSTLPNTLVMGIPLLKGMYGN-------------------FS +GDLMVQIVVLQCIIWYTLML------------------FLFEYRGAKLLISEQFP-DTAGSIVSIHVDSDIM +SLDGRQ-PLETEAEIKEDGKLHVTVRRSNASRSDIYS-----RRSQGL-SATPRPSNLTNAEIYSLQSSRNP +TPRGSSFNHTDFY---------------SMMASGGGRNSNFGPGEA---------------VFGSKGPTPRP +SNYEEDGGPAKPTAAGTAAGAGRFHYQSGGSGGGGGAHYPAPNPGMFSPNTGGGGGTAAKGNAPVVGGKRQD +GN------GRDLHMFVWSSSASPVSDVFGGGGGNHHADYSTATNDHQKDVKISVPQGNSNDNQYVEREEFSF +GNKDDDSKVLATDGGNNISNKTTQAKVMPPTSVMTRLILIMVWRKLIRNPNSYSSLFGITWSLI-SFKWNIE +MP------------ALIAKSISILSDAGLGMAMFSLGLFMALNPRIIACGNRRAAFA--------AAMRFVV +GPAVMLVASYAVGLRGV-LLHVAIIQ------------AALPQGIVPFVFAKEYNVHPDILSTAVIFGMLIA +LPITLLYY +>Q9FVF6_POPPZ/9-609 +HVMTAMVPLYVAMILA-YGSVKWWKIFTPDQCSGINRFVALFAVPLLSFHFISTNDPYNMNLRFITADSLQK +VIVLVVLALWTKLSK---RGCLEWTITLFSLSTLPNTLVMGIPLLKGMYGD-------------------YS +GSLMVQVVVLQCIIWYTLML------------------FMFEYRGAKLLISEQFP-DTAGSIVSIHVDSDIM +SLDGRQ-PLETEAAIKEDGKLHVTVRKSNASRSDIFS-----RRSQGLSSTTPRPSNLTNAEIYSLQSSRNP +TPRGSSFNHTDFY---------------SMMA--AGRNSNFGASDVY-------------GLSASRGPTPRP +SNFEEEHGGSNKPRFHHYHAPGGATHYPAPNPGMFSPTTAASKGVSANANNAAAAAAKKPNGQAQQKAED-- +-----------GRDLHMFVWSSSASPVSDVFGGHDYGAHDLKDVRVAVSPGKVEGQRENQEDYNLERDDFSF +GNRGLDRERNSHEGEKGGFD--GKPKAMPPTSVMTRLILIMVWRKLIRNPNTYSSLIGLIWSLV-SFRWNVK +MP------------LIIAKSISILSDAGLGMAMFSLGLFMALQPRIIACGNSIATFS--------MAVRFLT +GPAIMAAASIAVGIRGT-LLHIAIVQ------------AALPQGIVPFVFAKEYNVHPEILSTGVIFGMLIA +LPITLVYY +>B8AIF2_ORYSI/9-590 +HVMTAMVPLYVAMILA-YGSVKWWRIFTPDQCSGINRFVALFAVPLLSFHFISTNNPYTMNLRFIAADTLQK +LMVLAMLTAWSHLSR---RGSLEWTITLFSLSTLPNTLVMGIPLLKGMYGE-------------------FS +GSLMVQIVVLQCIIWYTLML------------------FMFEYRGARMLITEQFP-DTAANIASIVVDPDVV +SLDGRRDAIETETEVKEDGRIHVTVRRSNASRSDIYS-----RRSMGFSSTTPRPSNLTNAEIYSLQSSRNP +TPRGSSFNHTDFY---------------SMV----GRSSNFGAADA---------------FGVRTGATPRP +SNYEDDASKPKYPLPASNAAPMAGHYPAPNPAVSSAPKGAKKAATNGQAKGEDLHMFVWSS----------- +--------------------SASPVSDVFGGGAPDYNDAAAVKSPRKMDGAKDREDYVERDDFSFGNRGVMD +RDAEAGDEKAAAAAGADPSKAMAAPTAMPPTSVMTRLILIMVWRKLIRNPNTYSSLIGLIWSLV-CFRWNFE +MP------------AIVLKSISILSDAGLGMAMFSLGLFMALQPHIIACGNKVATYA--------MAVRFLA +GPAVMAAASFAVGLRGT-LLHVAIVQ------------AALPQGIVPFVFAKEYSVHPSILSTAVIFGMLIA +LPITLVYY +>PIN6_ARATH/9-565 +TVMCAMAPLYFAMFVA-YGSVKWCKIFTPAQCSGINRFVSVFAVPVLSFHFISQNNPYKMDTMFILADTLSK +IFVFVLLSLWAVFFK---AGGLDWLITLFSIATLPNTLVMGIPLLQAMYGD-------------------YT +QTLMVQLVVLQCIIWYTLLL------------------FLFELRAARLLIRAEFPGQAAGSIAKIQVDDDVI +SLDGMD-PLRTETETDVNGRIRLRIRRSVSSVPDSVMSSSLC--------LTPRASNLSNAEIFSVN----- +-----TPNNRFFHGGGGSGTLQFYNGSNEIMF-CNGDLGGFGFTRPGLGASPRRLSGYASSDAYSLQPTPRA +SNFNELDVNGNGTPVWMKSPAAGRIYRQSSPKMMWESGQRHAAK---------------------------- +--------------------------------------DINGSVPEKEISFRDALKAAPQATAAGGGASMEE +GAAGKDTTPVA-AIG-K-QE-------MPSAIVMMRLILTVVGRKLSRNPNTYSSLLGLVWSLI-SFKWNIP +MP------------NIVDFSIKIISDAGLGMAMFSLGLFMALQPKMIPCGAKKATMG--------MLIRFIS +GPLFMAGASLLVGLRGS-RLHAAIVQ------------AALPQGIVPFVFAREYNLHPDLLSTLVIFGMIVS +LPVTILYY +>YFDV_ECOLI/4-307 +FFIGDLLPIIVIMLLG-YFSGRR-ETFSEDQARAFNKLVLNYALPAALFVSITRANREMIFADTRLTLVSLV +VIVGCFFFSWFGCYK-FFKRTHAEAAVCALIAGSPTIGFLGFAVLDPIYGD----------------SVSTG +LVVAIISIIVNAITIPIGLY------------------LLNPSSGADGKK---------------------- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------NSNLSALISAAKEPVVWAPVLATILVLV-GVKIP-- +--------------AAWDPTFNLIAKANSGVAVFAAGLTLAAHKFEFSAEIAYN-----------TFLKLIL +MPLALLLVGMACHLNSE-HLQMMVLA------------GALPPAFSGIIIASRFNVYTRTGTASLAVSVLGF +VVTAPLWI +>YWKB_BACSU/5-315 +DILILLAPIFFVIVLG-WFAGHF-GSYDAKSAKGVSTLVTKYALPAHFIAGILTTSRSEFLSQVPLMISLII +GIVGFYIIILLVCRF-IFKYDLTNSSVFSLNSAQPTFAFMGIPVLGSLFGA-------------------NE +VAIPIAVTGIVVNAILDPLA------------------IIIATVGESSKKNEESGD---------------- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------SFWKMTGKSILHGLCEPLAAAPLISMILVLVFNFTLP-- +--------------ELGVKMLDQLGSTTSGVALFAVGVTVGIRKIKLSMPAIG-----------IALLKVAV +QPALMFLIALAIGLPADQTTKAILL-------------VAFPGSAVAAMIATRFEKQEEETATAFVVSAILS +LISLPIII +>P71425_KLEPN/4-313 +VIIHALAPIFVIMLLG-FWAGKA-GMVDNKNVSLLNIFVMDFALPATLFSATVQTPWAGIVAQSPLVLVLTG +AMWITYAAIYFLATS-VFKRTPQDGAVLTLTVALPNYAALGLPILGSVLGE------------------GAS +TSLSVAVSIACGSVLMTPFC------------------LLILEREKARAAGENSG----------------- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------STLAMLPVLMWRSVKKPIVWGPLLGVVLSAI-GIKMP-- +--------------DLLLASIKPLGLAATAAALFLTGVILSARKLQLNALIAAS-----------TIVKLLV +QPFIAWGLVMLLGLHGSIAITAILM-------------IALAAGFFGVVFGNRFGVQSPDAEAVLLLSSVLC +ILSLPLFI +>Q98L58_RHILO/3-308 +PLTETVLFVFSLVALG-YLAGLT-GYLRPASGEGISDFAVSVAMPLLLFQTMVKADFHG--VAPWPLWGAYF +TAVAITWAAGHLVTTRIFGRDARAGVVGGVSSAYSNVVLLGAPFILGIFGP-----------------SGFE +VLSLLVSVHLPVMMMASIVL------------------FEMFGRGGGEHV---------------------- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------HPLRVLRSFLRRLFINPLIIGILLGLAWRLS-GVPLP-- +--------------SLVMRLVDALANTAGPVALFAMGLSLRRFGVSGNVRPALA----------LSALKLFL +MPALVLAFVLLLGLPPL-TAKVAVVV------------AALPSGINSYLIAVQFNTGQALASNQMTIATACA +AVTTAFWL +>O67397_AQUAE/2-289 +FIYEKVFFILLIIAFA-YTLKRG-GIFKEEHALPFINYVIYFALPFTIFKNLRF---LEIGKEVLGVVLIAW +GAIFLSILFAFLFGK-FLKLEEKTLRAFLLVSSFGNTAFMGYPFLYALEGN-------------------EG +LKYAILYDQLGSFLMVITLG---------------------------------------------------- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------LFLAIGKFDLKELILFPPFIALVLSFLLHGV-RFP---- +--------------QFFEHSVEIISGSLIPVILFSLGLRLNFTDMKSDYRTLFSA----------LFIKMFL +VPLLILVFLKIFGLTSL-PYRVALIE------------SAMPPMVFAGVLALKYELDFRLAFSAITLGIVIS +LFTVPVFR +>Q97M34_CLOAB/2-296 +YVFEQIVILFLIMGIG-YYAAKS-KIIDDDTTSHLSNFIVSITLPLMILTSFNVEYSRKTVITIINLLVFSV +AAFIISIVIGKII---SFKFAMDKRDILMFMSIFSNCGFIGFPVLKVVYGN-------------------KG +VLYTSIFNLVYNVFIWTIGI------------------VIINDKREKIDY---------------------- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +-------------------------------------------KKILFNHNIIAVIVGVFLMLL-SIKIP-- +--------------YVMSSAFNLIGSMTAPLSMIVIGSILA--------GVDFNDIFKDWSLYYIAILRLII +IPLIIYFALKPFQINKI-VIGVIIIC------------EAMPGGTLCPILAKSCNRNFKYASKIVLITTILS +MMTIPFMT +>YB8B_YEAST/13-413 +LVFESVLQVVIIALAG-FWSASS-GLLPKQSQKIISLLNVDLFTPCLIFSKLAKSLSMAKIFEIAIIPIFFG +LTTGISFISGKIMSR-ILDLDKDETNFVVANSVFGNSNSLPVSLTLSLAYTLPNLTWDQIPNDNRDNVASRG +ILYLLIFQQIGQMLRWSWGY------------------NKLMKWSGENTQHMPPSQVQSLLERTPNIDNEEL +VNEEQEEQELLEEENNRMNSSFLSSSSIGDKIWQKSCTVFER------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +-------------------------------------------IRANLNPPLYSMIFAVVVAAI-GPLQREL +F------MEDGFINNTFAEAVTQLGSVSIPLILVVLGSNLYPSA-----EVFPKTVHHSKLLIGSIIGRMIL +PSCFLLPIIAIAV-----KYINVSILDDPIFLVVGFLLTVSPPAIQLTQITQLNEFFEAEMADILFWGYAVL +SLPVSIIV +>YDQ4_SCHPO/18-440 +PIIESDLEVIVIALGG-YVLAKK-GFLPRDAQKVISSLNVYFFTPCLVFEKVGNGLNLKMLIDLSLLPVFYV +IISAASILISFLLAK-LFRLTPRQRNFATACITFQNSNSLPLALVSSLATTVKDLLWDKIPDDTPDKVASRG +IMYLLIFSQLGQALRWSYGY------------------RILLSPNQPEDPLPIGNRSWSHSDVNEEEIQNLL +ASSANVDGVQNSVQANEGSTVQTDSSAISKNDNVQVETSNEEVGGFGAASSKISK----------------- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------------FIVLLLDFFSPPLYSLFIALFIAVV-PPLQRFF +F------EEGSFVEGSITSGIRMAGQVAVPMILVVLGASLATDISKTEPTQEVRKNNDTRVIIVCLLGRMVV +VPLALLPAFSLLS-----YFSEISTVDDPVFVVVIFLLVGSPTAIQLTQICQLNGVFERECAKVLWWSYAVF +TPPNSLLL +>PILS4_ARATH/9-407 +ASSKPVVETLLITSVGFYLALDTVNLLGHDARKHLNNIVFYVFSPSLIGSRLADSVTYESLVKMWFMPVNVL +LTFMIGSLLGWIVIV-ITKPPSQLRGLIISCCASGNLGTMPLIIIPAICKE------KGGPFGDSESCEKYG +MGYVTLSMT--AFFISVYKHDTNWYVSGGNGLLMDLYINLMR------VLSNSPVETHTHSIESNYDDSCKV +QLISSK------------------------------------------EEEKEEDNHQVGRWEEVKQ----- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------RVVSLSKKVNLGSIFAPATIAAIIALVIGLI-TPLRNLI +IGTVAPF-------RVIQDSLTLLGDGAIPAMTLILGGNLLKGMRRSEVRSSEMKNSCIIGV---LVARYIL +LPVSGVLLVRGAY------KLDLVTS-EPLYQFVLLLQYAVPPAMNLGTKTQLFGAGESECSVIMLWTYSLA +AVSLTVWP +>PILS5_ARATH/9-388 +VASMPVIQVLFMSLVGAFMASDRCKLFPVEARNSMNKVVFVLFAPALMFANLAQTVTLEDIISWWFMPVNMG +LTFLIGGLLGWLVVK-ILKPPPYLEGLIVATCSAGNMGNLPIILVPAICDE------DKSPFGNRSVCRTVG +LSYASFSMALGGFYIWTYTF------------------RLIKGSAMKVQAIEESEKIAIKSSNSDLEADHKT +HLLGAP-----------------------------------------EDKENKVVKEKTGFWRKGVD----- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------FLHEI-----LEELLAPPTLGAIIGFIFGAV-RWLRNLI +IGDDAPL-------RIVQSTAKLLGDGTIPCMTIILGGNLIQG-----LRSSAVKPMVVLGI---VCVRYIA +MPIIGIGIVLTAA------NLGFLPA-DPLFQYVLMLQFTLPPAMNIGTMTQLYNVAQDECSVLMLWTYLVA +ILALTVWS +>PILS2_ARATH/18-441 +SGVVPLLKLICLTVIGLLLAHPKTQLVPRATFRLLSKLVFALFLPCLIFTELGESITLDNIVQWWFIPVNVL +LSAVVGSLIGYLVVL-ICRPPPEFNRFTIVMTAFGNTGNLLLAIVSSVCHT--------KTNPFGPNCNSRG +VSYVSFAQWVAVILVYTVVY------------------HMMEPPLEYYEVVEEEG-VEIEEINVENHDASRP +LLVEAEWPGIEDKETEHCKTPFIARVFNSISSFSQTSFPEVDLGGEYGGESSSPRSIQCLAEPRVMR----- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------RIRVVAEQTPVKHILQPPTIASLLAIIIGSV-PQLKSVV +FGYDAPL-------SFITDSLNIMGSAMVPSVMLVLGGMLSEGPNESTLGLRTTIGI--------SVARLLV +LPLVGIGIVMSAD------KLGLISSADPMFKFVLLLQYSTPSAILLGAIASLRGYAVREASALLFWQHIFA +LLSLTFYI +>PILS6_ARATH/30-423 +IAVMPIAKVFTMCFLGLLMASKYVNILPPSGRKLLNGLVFSLLLPCLIFSQLGQAVTLQKMLQWWFIPVNVV +LGTISGSIIGFIVAS-IVRPPYPYFKFTIIQIGVGNIGNVPLVLLAALCRD------TSNPFGDSEKCSIDG +TAYISFGQWVGAIILYTYVY------------------QMFAPPPEGFDAEEENLALKTLPVDAAPEQVPLL +TQNFPKDFSPTQDL--------------------------------LPVQSTEPRGRGVSRKGKIAQ----- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------IFVFLYEKLKLKQIVQPAIVASILAMILGAI-PFTKKLI +FTNGAPL-------FFFTDSCMILGDAMIPCILLALGGNLINGPGSSKLGFKTTAAI--------IIGRLVL +VPPVGLGIVTVAD------KLGFLPADDKMFRFVLLLQHTMPTSVLSGAVANLRGCG-RESAAVLFWVHIFA +IFSMAGWM +>PIN4_ARATH/9-611 +TVLTAVVPLYVAMILA-YGSVQWWKIFSPDQCSGINRFVAIFAVPLLSFHFISTNDPYAMNFRFVAADTLQK +IIMLVLLALWANLTK---NGSLEWMITIFSLSTLPNTLVMGIPLLIAMYGT-------------------YA +GSLMVQVVVLQCIIWYTLLL------------------FLFEYRGAKLLIMEQFP-ETGASIVSFKVESDVV +SLDGHD-FLETDAEIGNDGKLHVTVRKSNASRRSLMM--------------TPRPSNLTGAEIYSLS----S +TPRGSNFNHSDFY---------------SVMGFPGGRLSNFGPADLY-------------SVQSSRGPTPRP +SNFEENNAVKYGFYNNTNSSVPAAGSYPAPNPEFSTGTGVSTKPNKIPKENQQQLQEKDSKASHDAKELHMF +VWSSSASPVSDVFGGGAGDNVATEQSEQGAKEIRMVVSDQPRKSNARGGGDDIGGLDSGEGEREIEKATAGL +NKMGSNSTAELEAAG-G-DGGGNNGTHMPPTSVMTRLILIMVWRKLIRNPNTYSSLIGLIWALV-AYRWHVA +MP------------KILQQSISILSDAGLGMAMFSLGLFMALQPKIIACGNSVATFA--------MAVRFIT +GPAIMAVAGIAIGLHGD-LLRIAIVQ------------AALPQGIVPFVFAKEYNVHPTILSTGVIFGMLIA +LPITLVYY +>PIN7_ARATH/9-614 +TVLTAVIPLYVAMILA-YGSVRWWKIFSPDQCSGINRFVAIFAVPLLSFHFISSNNPYAMNLRFIAADTLQK +LIMLTLLIIWANFTR---SGSLEWSITIFSLSTLPNTLVMGIPLLIAMYGE-------------------YS +GSLMVQIVVLQCIIWYTLLL------------------FLFEYRGAKILIMEQFP-ETGASIVSFKVESDVV +SLDGHD-FLETDAQIGDDGKLHVTVRKSNASRRSFYG--------GGGTNMTPRPSNLTGAEIYSL----NT +TPRGSNFNHSDFY---------------SMMGFPGGRLSNFGPADMY-------------SVQSSRGPTPRP +SNFEESCAMASSPRFGYYPGGAPGSYPAPNPEFSTGNKTGSKAPKENHHHVGKSNSNDAKELHMFVWGSNGS +PV-----SDRAGLQVDNGANEQVGKSDQGGAKEIRMLISDHTQNGENKAGPMNGDYGGEEESERVKEVPNGL +HKLRCNSTAELNPKEAIETGETVPVKHMPPASVMTRLILIMVWRKLIRNPNTYSSLIGLIWALV-AFRWDVA +MP------------KIIQQSISILSDAGLGMAMFSLGLFMALQPKLIACGNSTATFA--------MAVRFFT +GPAVMAVAAMAIGLRGD-LLRVAIVQ------------AALPQGIVPFVFAKEYNVHPAILSTGVIFGMLIA +LPITLVYY
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/seed2.aln Mon Jul 14 18:16:36 2025 +0000 @@ -0,0 +1,216 @@ +>PINI_ARATH/9-617 +HVMTAMVPLYVAMILA-YGSVKWWKIFTPDQCSGINRFVALFAVPLLSFHFIAANNPYAMNLRFLAADSLQK +VIVLSLLFLWCKLSR---NGSLDWTITLFSLSTLPNTLVMGIPLLKGMYGN-------------------FS +GDLMVQIVVLQCIIWYTLML------------------FLFEYRGAKLLISEQFP-DTAGSIVSIHVDSDIM +SLDGRQ-PLETEAEIKEDGKLHVTVRRSNASRSDIYS-----RRSQGL-SATPRPSNLTNAEIYSLQSSRNP +TPRGSSFNHTDFY---------------SMMASGGGRNSNFGPGEA---------------VFGSKGPTPRP +SNYEEDGGPAKPTAAGTAAGAGRFHYQSGGSGGGGGAHYPAPNPGMFSPNTGGGGGTAAKGNAPVVGGKRQD +GN------GRDLHMFVWSSSASPVSDVFGGGGGNHHADYSTATNDHQKDVKISVPQGNSNDNQYVEREEFSF +GNKDDDSKVLATDGGNNISNKTTQAKVMPPTSVMTRLILIMVWRKLIRNPNSYSSLFGITWSLI-SFKWNIE +MP------------ALIAKSISILSDAGLGMAMFSLGLFMALNPRIIACGNRRAAFA--------AAMRFVV +GPAVMLVASYAVGLRGV-LLHVAIIQ------------AALPQGIVPFVFAKEYNVHPDILSTAVIFGMLIA +LPITLLYY +>Q9FVF6_POPPZ/9-609 +HVMTAMVPLYVAMILA-YGSVKWWKIFTPDQCSGINRFVALFAVPLLSFHFISTNDPYNMNLRFITADSLQK +VIVLVVLALWTKLSK---RGCLEWTITLFSLSTLPNTLVMGIPLLKGMYGD-------------------YS +GSLMVQVVVLQCIIWYTLML------------------FMFEYRGAKLLISEQFP-DTAGSIVSIHVDSDIM +SLDGRQ-PLETEAAIKEDGKLHVTVRKSNASRSDIFS-----RRSQGLSSTTPRPSNLTNAEIYSLQSSRNP +TPRGSSFNHTDFY---------------SMMA--AGRNSNFGASDVY-------------GLSASRGPTPRP +SNFEEEHGGSNKPRFHHYHAPGGATHYPAPNPGMFSPTTAASKGVSANANNAAAAAAKKPNGQAQQKAED-- +-----------GRDLHMFVWSSSASPVSDVFGGHDYGAHDLKDVRVAVSPGKVEGQRENQEDYNLERDDFSF +GNRGLDRERNSHEGEKGGFD--GKPKAMPPTSVMTRLILIMVWRKLIRNPNTYSSLIGLIWSLV-SFRWNVK +MP------------LIIAKSISILSDAGLGMAMFSLGLFMALQPRIIACGNSIATFS--------MAVRFLT +GPAIMAAASIAVGIRGT-LLHIAIVQ------------AALPQGIVPFVFAKEYNVHPEILSTGVIFGMLIA +LPITLVYY +>B8AIF2_ORYSI/9-590 +HVMTAMVPLYVAMILA-YGSVKWWRIFTPDQCSGINRFVALFAVPLLSFHFISTNNPYTMNLRFIAADTLQK +LMVLAMLTAWSHLSR---RGSLEWTITLFSLSTLPNTLVMGIPLLKGMYGE-------------------FS +GSLMVQIVVLQCIIWYTLML------------------FMFEYRGARMLITEQFP-DTAANIASIVVDPDVV +SLDGRRDAIETETEVKEDGRIHVTVRRSNASRSDIYS-----RRSMGFSSTTPRPSNLTNAEIYSLQSSRNP +TPRGSSFNHTDFY---------------SMV----GRSSNFGAADA---------------FGVRTGATPRP +SNYEDDASKPKYPLPASNAAPMAGHYPAPNPAVSSAPKGAKKAATNGQAKGEDLHMFVWSS----------- +--------------------SASPVSDVFGGGAPDYNDAAAVKSPRKMDGAKDREDYVERDDFSFGNRGVMD +RDAEAGDEKAAAAAGADPSKAMAAPTAMPPTSVMTRLILIMVWRKLIRNPNTYSSLIGLIWSLV-CFRWNFE +MP------------AIVLKSISILSDAGLGMAMFSLGLFMALQPHIIACGNKVATYA--------MAVRFLA +GPAVMAAASFAVGLRGT-LLHVAIVQ------------AALPQGIVPFVFAKEYSVHPSILSTAVIFGMLIA +LPITLVYY +>PIN6_ARATH/9-565 +TVMCAMAPLYFAMFVA-YGSVKWCKIFTPAQCSGINRFVSVFAVPVLSFHFISQNNPYKMDTMFILADTLSK +IFVFVLLSLWAVFFK---AGGLDWLITLFSIATLPNTLVMGIPLLQAMYGD-------------------YT +QTLMVQLVVLQCIIWYTLLL------------------FLFELRAARLLIRAEFPGQAAGSIAKIQVDDDVI +SLDGMD-PLRTETETDVNGRIRLRIRRSVSSVPDSVMSSSLC--------LTPRASNLSNAEIFSVN----- +-----TPNNRFFHGGGGSGTLQFYNGSNEIMF-CNGDLGGFGFTRPGLGASPRRLSGYASSDAYSLQPTPRA +SNFNELDVNGNGTPVWMKSPAAGRIYRQSSPKMMWESGQRHAAK---------------------------- +--------------------------------------DINGSVPEKEISFRDALKAAPQATAAGGGASMEE +GAAGKDTTPVA-AIG-K-QE-------MPSAIVMMRLILTVVGRKLSRNPNTYSSLLGLVWSLI-SFKWNIP +MP------------NIVDFSIKIISDAGLGMAMFSLGLFMALQPKMIPCGAKKATMG--------MLIRFIS +GPLFMAGASLLVGLRGS-RLHAAIVQ------------AALPQGIVPFVFAREYNLHPDLLSTLVIFGMIVS +LPVTILYY +>YFDV_ECOLI/4-307 +FFIGDLLPIIVIMLLG-YFSGRR-ETFSEDQARAFNKLVLNYALPAALFVSITRANREMIFADTRLTLVSLV +VIVGCFFFSWFGCYK-FFKRTHAEAAVCALIAGSPTIGFLGFAVLDPIYGD----------------SVSTG +LVVAIISIIVNAITIPIGLY------------------LLNPSSGADGKK---------------------- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------NSNLSALISAAKEPVVWAPVLATILVLV-GVKIP-- +--------------AAWDPTFNLIAKANSGVAVFAAGLTLAAHKFEFSAEIAYN-----------TFLKLIL +MPLALLLVGMACHLNSE-HLQMMVLA------------GALPPAFSGIIIASRFNVYTRTGTASLAVSVLGF +VVTAPLWI +>YWKB_BACSU/5-315 +DILILLAPIFFVIVLG-WFAGHF-GSYDAKSAKGVSTLVTKYALPAHFIAGILTTSRSEFLSQVPLMISLII +GIVGFYIIILLVCRF-IFKYDLTNSSVFSLNSAQPTFAFMGIPVLGSLFGA-------------------NE +VAIPIAVTGIVVNAILDPLA------------------IIIATVGESSKKNEESGD---------------- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------SFWKMTGKSILHGLCEPLAAAPLISMILVLVFNFTLP-- +--------------ELGVKMLDQLGSTTSGVALFAVGVTVGIRKIKLSMPAIG-----------IALLKVAV +QPALMFLIALAIGLPADQTTKAILL-------------VAFPGSAVAAMIATRFEKQEEETATAFVVSAILS +LISLPIII +>P71425_KLEPN/4-313 +VIIHALAPIFVIMLLG-FWAGKA-GMVDNKNVSLLNIFVMDFALPATLFSATVQTPWAGIVAQSPLVLVLTG +AMWITYAAIYFLATS-VFKRTPQDGAVLTLTVALPNYAALGLPILGSVLGE------------------GAS +TSLSVAVSIACGSVLMTPFC------------------LLILEREKARAAGENSG----------------- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------STLAMLPVLMWRSVKKPIVWGPLLGVVLSAI-GIKMP-- +--------------DLLLASIKPLGLAATAAALFLTGVILSARKLQLNALIAAS-----------TIVKLLV +QPFIAWGLVMLLGLHGSIAITAILM-------------IALAAGFFGVVFGNRFGVQSPDAEAVLLLSSVLC +ILSLPLFI +>Q98L58_RHILO/3-308 +PLTETVLFVFSLVALG-YLAGLT-GYLRPASGEGISDFAVSVAMPLLLFQTMVKADFHG--VAPWPLWGAYF +TAVAITWAAGHLVTTRIFGRDARAGVVGGVSSAYSNVVLLGAPFILGIFGP-----------------SGFE +VLSLLVSVHLPVMMMASIVL------------------FEMFGRGGGEHV---------------------- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------HPLRVLRSFLRRLFINPLIIGILLGLAWRLS-GVPLP-- +--------------SLVMRLVDALANTAGPVALFAMGLSLRRFGVSGNVRPALA----------LSALKLFL +MPALVLAFVLLLGLPPL-TAKVAVVV------------AALPSGINSYLIAVQFNTGQALASNQMTIATACA +AVTTAFWL +>O67397_AQUAE/2-289 +FIYEKVFFILLIIAFA-YTLKRG-GIFKEEHALPFINYVIYFALPFTIFKNLRF---LEIGKEVLGVVLIAW +GAIFLSILFAFLFGK-FLKLEEKTLRAFLLVSSFGNTAFMGYPFLYALEGN-------------------EG +LKYAILYDQLGSFLMVITLG---------------------------------------------------- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------LFLAIGKFDLKELILFPPFIALVLSFLLHGV-RFP---- +--------------QFFEHSVEIISGSLIPVILFSLGLRLNFTDMKSDYRTLFSA----------LFIKMFL +VPLLILVFLKIFGLTSL-PYRVALIE------------SAMPPMVFAGVLALKYELDFRLAFSAITLGIVIS +LFTVPVFR +>Q97M34_CLOAB/2-296 +YVFEQIVILFLIMGIG-YYAAKS-KIIDDDTTSHLSNFIVSITLPLMILTSFNVEYSRKTVITIINLLVFSV +AAFIISIVIGKII---SFKFAMDKRDILMFMSIFSNCGFIGFPVLKVVYGN-------------------KG +VLYTSIFNLVYNVFIWTIGI------------------VIINDKREKIDY---------------------- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +-------------------------------------------KKILFNHNIIAVIVGVFLMLL-SIKIP-- +--------------YVMSSAFNLIGSMTAPLSMIVIGSILA--------GVDFNDIFKDWSLYYIAILRLII +IPLIIYFALKPFQINKI-VIGVIIIC------------EAMPGGTLCPILAKSCNRNFKYASKIVLITTILS +MMTIPFMT +>YB8B_YEAST/13-413 +LVFESVLQVVIIALAG-FWSASS-GLLPKQSQKIISLLNVDLFTPCLIFSKLAKSLSMAKIFEIAIIPIFFG +LTTGISFISGKIMSR-ILDLDKDETNFVVANSVFGNSNSLPVSLTLSLAYTLPNLTWDQIPNDNRDNVASRG +ILYLLIFQQIGQMLRWSWGY------------------NKLMKWSGENTQHMPPSQVQSLLERTPNIDNEEL +VNEEQEEQELLEEENNRMNSSFLSSSSIGDKIWQKSCTVFER------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +-------------------------------------------IRANLNPPLYSMIFAVVVAAI-GPLQREL +F------MEDGFINNTFAEAVTQLGSVSIPLILVVLGSNLYPSA-----EVFPKTVHHSKLLIGSIIGRMIL +PSCFLLPIIAIAV-----KYINVSILDDPIFLVVGFLLTVSPPAIQLTQITQLNEFFEAEMADILFWGYAVL +SLPVSIIV +>YDQ4_SCHPO/18-440 +PIIESDLEVIVIALGG-YVLAKK-GFLPRDAQKVISSLNVYFFTPCLVFEKVGNGLNLKMLIDLSLLPVFYV +IISAASILISFLLAK-LFRLTPRQRNFATACITFQNSNSLPLALVSSLATTVKDLLWDKIPDDTPDKVASRG +IMYLLIFSQLGQALRWSYGY------------------RILLSPNQPEDPLPIGNRSWSHSDVNEEEIQNLL +ASSANVDGVQNSVQANEGSTVQTDSSAISKNDNVQVETSNEEVGGFGAASSKISK----------------- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------------FIVLLLDFFSPPLYSLFIALFIAVV-PPLQRFF +F------EEGSFVEGSITSGIRMAGQVAVPMILVVLGASLATDISKTEPTQEVRKNNDTRVIIVCLLGRMVV +VPLALLPAFSLLS-----YFSEISTVDDPVFVVVIFLLVGSPTAIQLTQICQLNGVFERECAKVLWWSYAVF +TPPNSLLL +>PILS4_ARATH/9-407 +ASSKPVVETLLITSVGFYLALDTVNLLGHDARKHLNNIVFYVFSPSLIGSRLADSVTYESLVKMWFMPVNVL +LTFMIGSLLGWIVIV-ITKPPSQLRGLIISCCASGNLGTMPLIIIPAICKE------KGGPFGDSESCEKYG +MGYVTLSMT--AFFISVYKHDTNWYVSGGNGLLMDLYINLMR------VLSNSPVETHTHSIESNYDDSCKV +QLISSK------------------------------------------EEEKEEDNHQVGRWEEVKQ----- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------RVVSLSKKVNLGSIFAPATIAAIIALVIGLI-TPLRNLI +IGTVAPF-------RVIQDSLTLLGDGAIPAMTLILGGNLLKGMRRSEVRSSEMKNSCIIGV---LVARYIL +LPVSGVLLVRGAY------KLDLVTS-EPLYQFVLLLQYAVPPAMNLGTKTQLFGAGESECSVIMLWTYSLA +AVSLTVWP +>PILS5_ARATH/9-388 +VASMPVIQVLFMSLVGAFMASDRCKLFPVEARNSMNKVVFVLFAPALMFANLAQTVTLEDIISWWFMPVNMG +LTFLIGGLLGWLVVK-ILKPPPYLEGLIVATCSAGNMGNLPIILVPAICDE------DKSPFGNRSVCRTVG +LSYASFSMALGGFYIWTYTF------------------RLIKGSAMKVQAIEESEKIAIKSSNSDLEADHKT +HLLGAP-----------------------------------------EDKENKVVKEKTGFWRKGVD----- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------FLHEI-----LEELLAPPTLGAIIGFIFGAV-RWLRNLI +IGDDAPL-------RIVQSTAKLLGDGTIPCMTIILGGNLIQG-----LRSSAVKPMVVLGI---VCVRYIA +MPIIGIGIVLTAA------NLGFLPA-DPLFQYVLMLQFTLPPAMNIGTMTQLYNVAQDECSVLMLWTYLVA +ILALTVWS +>PILS2_ARATH/18-441 +SGVVPLLKLICLTVIGLLLAHPKTQLVPRATFRLLSKLVFALFLPCLIFTELGESITLDNIVQWWFIPVNVL +LSAVVGSLIGYLVVL-ICRPPPEFNRFTIVMTAFGNTGNLLLAIVSSVCHT--------KTNPFGPNCNSRG +VSYVSFAQWVAVILVYTVVY------------------HMMEPPLEYYEVVEEEG-VEIEEINVENHDASRP +LLVEAEWPGIEDKETEHCKTPFIARVFNSISSFSQTSFPEVDLGGEYGGESSSPRSIQCLAEPRVMR----- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------RIRVVAEQTPVKHILQPPTIASLLAIIIGSV-PQLKSVV +FGYDAPL-------SFITDSLNIMGSAMVPSVMLVLGGMLSEGPNESTLGLRTTIGI--------SVARLLV +LPLVGIGIVMSAD------KLGLISSADPMFKFVLLLQYSTPSAILLGAIASLRGYAVREASALLFWQHIFA +LLSLTFYI +>PILS6_ARATH/30-423 +IAVMPIAKVFTMCFLGLLMASKYVNILPPSGRKLLNGLVFSLLLPCLIFSQLGQAVTLQKMLQWWFIPVNVV +LGTISGSIIGFIVAS-IVRPPYPYFKFTIIQIGVGNIGNVPLVLLAALCRD------TSNPFGDSEKCSIDG +TAYISFGQWVGAIILYTYVY------------------QMFAPPPEGFDAEEENLALKTLPVDAAPEQVPLL +TQNFPKDFSPTQDL--------------------------------LPVQSTEPRGRGVSRKGKIAQ----- +------------------------------------------------------------------------ +------------------------------------------------------------------------ +------------------------------------------------------------------------ +---------------------------------IFVFLYEKLKLKQIVQPAIVASILAMILGAI-PFTKKLI +FTNGAPL-------FFFTDSCMILGDAMIPCILLALGGNLINGPGSSKLGFKTTAAI--------IIGRLVL +VPPVGLGIVTVAD------KLGFLPADDKMFRFVLLLQHTMPTSVLSGAVANLRGCG-RESAAVLFWVHIFA +IFSMAGWM +>PIN4_ARATH/9-611 +TVLTAVVPLYVAMILA-YGSVQWWKIFSPDQCSGINRFVAIFAVPLLSFHFISTNDPYAMNFRFVAADTLQK +IIMLVLLALWANLTK---NGSLEWMITIFSLSTLPNTLVMGIPLLIAMYGT-------------------YA +GSLMVQVVVLQCIIWYTLLL------------------FLFEYRGAKLLIMEQFP-ETGASIVSFKVESDVV +SLDGHD-FLETDAEIGNDGKLHVTVRKSNASRRSLMM--------------TPRPSNLTGAEIYSLS----S +TPRGSNFNHSDFY---------------SVMGFPGGRLSNFGPADLY-------------SVQSSRGPTPRP +SNFEENNAVKYGFYNNTNSSVPAAGSYPAPNPEFSTGTGVSTKPNKIPKENQQQLQEKDSKASHDAKELHMF +VWSSSASPVSDVFGGGAGDNVATEQSEQGAKEIRMVVSDQPRKSNARGGGDDIGGLDSGEGEREIEKATAGL +NKMGSNSTAELEAAG-G-DGGGNNGTHMPPTSVMTRLILIMVWRKLIRNPNTYSSLIGLIWALV-AYRWHVA +MP------------KILQQSISILSDAGLGMAMFSLGLFMALQPKIIACGNSVATFA--------MAVRFIT +GPAIMAVAGIAIGLHGD-LLRIAIVQ------------AALPQGIVPFVFAKEYNVHPTILSTGVIFGMLIA +LPITLVYY +>PIN7_ARATH/9-614 +TVLTAVIPLYVAMILA-YGSVRWWKIFSPDQCSGINRFVAIFAVPLLSFHFISSNNPYAMNLRFIAADTLQK +LIMLTLLIIWANFTR---SGSLEWSITIFSLSTLPNTLVMGIPLLIAMYGE-------------------YS +GSLMVQIVVLQCIIWYTLLL------------------FLFEYRGAKILIMEQFP-ETGASIVSFKVESDVV +SLDGHD-FLETDAQIGDDGKLHVTVRKSNASRRSFYG--------GGGTNMTPRPSNLTGAEIYSL----NT +TPRGSNFNHSDFY---------------SMMGFPGGRLSNFGPADMY-------------SVQSSRGPTPRP +SNFEESCAMASSPRFGYYPGGAPGSYPAPNPEFSTGNKTGSKAPKENHHHVGKSNSNDAKELHMFVWGSNGS +PV-----SDRAGLQVDNGANEQVGKSDQGGAKEIRMLISDHTQNGENKAGPMNGDYGGEEESERVKEVPNGL +HKLRCNSTAELNPKEAIETGETVPVKHMPPASVMTRLILIMVWRKLIRNPNTYSSLIGLIWALV-AFRWDVA +MP------------KIIQQSISILSDAGLGMAMFSLGLFMALQPKLIACGNSTATFA--------MAVRFFT +GPAVMAVAAMAIGLRGD-LLRVAIVQ------------AALPQGIVPFVFAKEYNVHPAILSTGVIFGMLIA +LPITLVYY